No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
543 |
4. Check minimum number of eventsNone |
543 |
5. Include endpointsNone |
543 |
6. Filter based on genotype QC (FinnGen only) |
503 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H15
- Name in latin
- Scleritis
Similar endpoints
↥List of similar endpoints to
Scleritis
based on the number of shared cases.
Similar with more cases:
- Scleritis and episcleritis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2446 | 1435 | 995 |
| Only index persons | 2329 | 1379 | 950 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 51.11 | 53.37 | 48.04 |
| Only index persons | 50.92 | 53.12 | 47.73 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 503 | 345 | 158 |
| Unadjusted period prevalence (%) | 0.11 | 0.12 | 0.07 |
| Median age at first event (years) | 53.97 | 52.58 | 57.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 520
- Matched controls
- 5200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H15.0
ICD-10 Finland
Scleritis
+∞
307.7
509
*
H15.1
ICD-10 Finland
Episcleritis
331.2
198.9
190
9
H57.1
ICD-10 Finland
Ocular pain
17.4
143.5
130
98
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
356.2
137.4
133
5
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
4.8
70.8
282
1021
H16.0
ICD-10 Finland
Corneal ulcer
14.0
63.4
61
49
S01BC03
ATC
diclofenac; ophthalmic
17.6
60.6
51
32
H02AB06
ATC
prednisolone; systemic
4.6
57.8
369
1811
L04AX03
ATC
methotrexate; systemic
5.4
51.9
120
272
S01BA01
ATC
dexamethasone; ophthalmic
10.0
50.8
61
68
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.9
50.2
320
1518
H04.10
ICD-10 Finland
Dry eye syndrome
4.6
47.8
141
389
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.9
44.9
116
287
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.8
40.5
165
569
L04AX01
ATC
azathioprine; systemic
7.7
39.4
58
83
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
114.0
39.3
42
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
5.1
37.8
88
198
S01BA04
ATC
prednisolone; ophthalmic
13.9
36.0
34
26
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
35.8
34
*
F01
ICPC
Eye pain
8.0
35.4
50
68
H16.9
ICD-10 Finland
Keratitis, unspecified
99.4
34.2
37
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.4
32.7
93
245
A02BC02
ATC
pantoprazole; systemic
3.8
31.6
428
2875
A07EC01
ATC
sulfasalazine; oral, rectal
4.7
30.1
76
182
H02AB07
ATC
prednisone; oral
3.4
26.7
114
395
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
26.3
294
1707
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.4
26.2
73
188
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.3
24.6
68
174
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.7
24.1
60
141
XCD10
NOMESCO Finland
Electrophysiological examination of eye
8.1
24.1
33
43
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.8
23.8
81
241
S01ED51
ATC
timolol, combinations; ophthalmic
4.4
21.5
58
145
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
21.3
213
1143
S01ED01
ATC
timolol; ophthalmic
7.3
20.1
30
43
S01AD03
ATC
aciclovir; ophthalmic
6.4
20.1
34
56
F02
ICPC
Red eye
4.7
18.8
45
102
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
6.1
18.6
33
57
L04AA13
ATC
[U] leflunomide
7.9
18.0
25
33
L01BA01
ATC
methotrexate; systemic
6.0
17.8
32
56
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
25.4
16.1
22
9
K50.8
ICD-10 Finland
Other Crohn disease
7.5
15.8
23
32
M25.5
ICD-10 Finland
Pain in joint
2.1
15.6
225
1366
S01BC05
ATC
ketorolac; ophthalmic
5.1
15.4
33
68
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.4
15.1
57
180
R51.80
ICD-10 Finland
Headache
2.4
14.9
120
571
F29
ICPC
Eye symptom/complaint other
2.8
14.7
84
338
L88
ICPC
Rheumatoid/seropositive arthritis
4.5
14.5
36
84
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
14.3
173
975
H11.3
ICD-10 Finland
Conjunctival haemorrhage
4.0
14.2
41
108
H20
ICD-10 Finland
Iridocyclitis
31.0
14.0
18
6
H20.8
ICD-10 Finland
Other iridocyclitis
+∞
13.6
13
*
P01BA02
ATC
hydroxychloroquine; oral
3.0
13.4
64
233
XCH00
NOMESCO Finland
Eye pressure measurement
4.2
13.3
36
90
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
13.3
74
293
H10
ICD-10 Finland
Conjunctivitis
3.1
13.3
59
206
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.2
13.0
27
54
L04AB04
ATC
adalimumab; parenteral
5.1
12.3
26
53
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
27.4
12.1
16
6
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.1
12.0
53
184
R51
ICD-10 Finland
Headache
3.3
11.9
47
153
36904
ICD-8 Finland
Other inflammatory diseases of eye, Scleritis
+∞
11.5
11
*
M13.9
ICD-10 Finland
Arthritis, unspecified
3.0
11.1
52
187
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.5
11.0
72
309
XCK10
NOMESCO Finland
Photography of fundus of eye
2.7
10.9
60
236
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
5.3
10.9
22
43
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
10.6
131
732
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
10.6
63
257
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
10.6
159
954
M05BA04
ATC
alendronic acid; oral
2.9
10.6
50
181
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.5
10.5
37
112
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
+∞
10.4
10
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
+∞
10.4
10
*
UJF32
NOMESCO Finland
Coloscopy
2.0
10.3
139
801
J01FA09
ATC
clarithromycin; systemic
1.9
10.2
187
1195
S01XA18
ATC
ciclosporin; ophthalmic
17.1
9.9
15
9
J01MA12
ATC
levofloxacin; systemic
2.1
9.8
102
534
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
9.7
56
226
J01MA02
ATC
ciprofloxacin; systemic
1.8
9.5
198
1310
UJF30
NOMESCO Finland
Ileoscopy through colon
2.4
9.4
69
311
CF2S4
NOMESCO Finland
Photography of conjunctiva
101.8
9.4
10
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.3
9.4
19
37
CS494
NOMESCO Finland
Other visual field testing
4.7
9.1
21
46
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
9.1
51
202
H53.2
ICD-10 Finland
Diplopia
4.0
9.1
26
68
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
8.9
128
750
J01AA02
ATC
doxycycline; systemic
2.0
8.8
414
3460
H16.2
ICD-10 Finland
Keratoconjunctivitis
50.9
8.7
10
*
N02AX02
ATC
tramadol; systemic, rectal
1.7
8.7
231
1633
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.5
8.7
55
232
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
11.8
8.6
15
13
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.5
8.6
30
90
S01FA04
ATC
cyclopentolate; ophthalmic
16.6
8.6
13
8
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
8.5
153
963
A02BC03
ATC
lansoprazole; oral
1.8
8.4
154
974
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
8.2
111
637
C10AC01
ATC
colestyramine; oral
4.1
8.1
22
55
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
8.1
118
692
S01EA05
ATC
brimonidine; ophthalmic
7.0
8.1
19
28
J02AC01
ATC
fluconazole; systemic
1.7
8.1
231
1655
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
8.1
201
1386
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
13.3
7.9
13
10
E0000UV, ,
ATC
1.7
7.9
226
1618
XCK00
NOMESCO Finland
Perimetry
3.0
7.9
35
122
N02BE01
ATC
paracetamol; systemic, rectal
2.4
7.8
473
4201
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.0
7.8
91
495
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.9
7.8
36
129
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.0
7.7
35
124
D07AC01
ATC
betamethasone; topical
1.7
7.7
196
1359
M45
ICD-10 Finland
Ankylosing spondylitis
6.9
7.6
18
27
L04AA06
ATC
mycophenolic acid; systemic
6.3
7.6
19
31
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.1
7.6
31
103
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.1
7.6
31
103
ZXA05
NOMESCO Finland
Left side
1.8
7.5
122
740
S01EE01
ATC
latanoprost; ophthalmic
3.1
7.5
32
109
M01AE02
ATC
naproxen; oral, rectal
1.7
7.5
313
2464
H18.8
ICD-10 Finland
Other specified disorders of cornea
81.2
7.4
8
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.2
7.4
69
344
J01DB01
ATC
cefalexin; oral
2.0
7.4
437
3787
A02BC05
ATC
esomeprazole; systemic
1.7
7.4
216
1548
H18.4
ICD-10 Finland
Corneal degeneration
+∞
7.3
7
*
L04AD01
ATC
ciclosporin; systemic
6.4
7.3
18
29
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.6
7.2
17
38
J01FA10
ATC
azithromycin; systemic
1.7
7.2
319
2540
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.3
7.1
18
43
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
7.0
55
256
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.3
6.9
54
250
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
7.7
6.9
15
20
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
6.9
78
419
M54.5
ICD-10 Finland
Low back pain
1.7
6.9
202
1444
R06AE07
ATC
cetirizine; oral
1.6
6.9
238
1773
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.4
6.9
50
225
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
6.8
104
617
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.6
6.8
22
63
G44.2
ICD-10 Finland
Tension-type headache
1.9
6.7
87
489
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
6.7
238
1779
K50.9
ICD-10 Finland
Crohn disease, unspecified
6.0
6.7
17
29
S01EC04
ATC
brinzolamide; ophthalmic
3.7
6.7
21
59
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
6.6
97
568
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
6.6
57
276
L04AA01
ATC
[U] ciclosporin
10.2
6.6
12
12
G51.0
ICD-10 Finland
Bell palsy
4.0
6.5
18
46
R01AD09
ATC
mometasone; nasal
1.6
6.4
251
1917
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
6.7
6.4
15
23
A01
ICPC
Pain general/multiple sites
2.1
6.3
62
315
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.4
6.3
42
181
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
11.2
6.3
11
10
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
6.3
120
761
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
6.3
6
*
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
27.0
6.2
8
*
R07.3
ICD-10 Finland
Other chest pain
2.1
6.2
61
310
TAB00
NOMESCO Finland
Lumbar puncture
2.6
6.2
34
134
J01FF01
ATC
clindamycin; systemic
1.7
6.1
144
966
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
6.1
102
621
M79.6
ICD-10 Finland
Pain in limb
1.6
6.1
237
1799
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.7
6.1
19
53
R03DC03
ATC
montelukast; oral
1.8
6.1
97
583
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.3
6.1
22
68
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.5
6.1
20
58
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.4
6.1
21
63
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
166
200
11.72
135.59
1.7
2.6
35.42
39.46
u/l
1.57
159
183
144
175
11.00
115.82
2.5
1.4
8.23
12.08
iu/ml
—
11
5
48
18
29.28
70.72
1.3
4.6
423.40
753.61
u/ml
0.93
48
18
144
339
5.49
60.25
2.6
2.5
29.87
14.86
au/ml
1.01
15
30
61
71
9.60
49.20
1.5
1.3
156.00
—
titre
—
5
0
245
1001
3.74
47.69
1.6
1.3
56.70
29.92
iu/ml
0.55
73
317
80
154
5.96
40.92
1.7
1.6
0.10
0.04
iu/ml
0.26
13
19
92
221
4.84
36.50
1.7
1.6
6.04
5.53
iu/ml
0.08
20
49
73
158
5.21
32.62
1.9
1.4
0.24
0.24
g/l
0.19
68
152
74
166
5.03
31.70
1.9
1.4
1.24
1.23
g/l
0.11
69
160
405
2656
3.37
30.59
13.8
9.6
4.20
4.01
e9/l
1.06
375
2325
193
929
2.71
24.98
1.4
1.3
6.09
9.21
u/ml
0.45
63
371
33
43
8.13
24.06
1.3
1.2
—
—
—
0
0
33
45
7.76
23.15
1.3
1.2
—
—
—
0
0
33
45
7.76
23.15
1.3
1.2
—
—
—
0
0
36
55
6.96
22.85
1.4
1.2
—
—
—
0
0
32
43
7.86
22.73
1.3
1.2
—
—
—
0
0
32
45
7.51
21.85
1.1
1.2
—
—
—
0
0
33
49
7.12
21.48
1.3
1.2
—
—
—
0
0
452
3439
3.40
21.27
8.3
4.1
13.01
10.81
mm/h
2.45
444
3235
25
31
8.42
18.91
1.2
1.1
—
—
—
0
0
68
212
3.54
18.50
1.2
1.2
1.14
1.16
u/ml
—
5
10
355
2473
2.37
18.49
6.3
3.5
0.00
0.63
estimate
0.51
61
484
351
2434
2.36
18.47
6.2
3.5
0.00
0.00
estimate
0.50
65
509
47
113
4.47
18.30
1.2
1.2
0.96
9.63
u/ml
—
5
9
353
2459
2.36
18.30
6.3
3.5
0.00
6.56
estimate
0.80
66
514
96
374
2.92
18.01
4.8
2.6
10.14
10.36
g/l
0.23
91
346
53
149
3.85
16.75
1.3
1.3
1.96
5.74
u/ml
—
9
28
20
6
34.57
15.84
1.4
1.0
—
—
—
0
0
51
149
3.69
15.23
1.2
1.2
3.91
2.60
u/ml
—
8
18
437
3489
2.58
14.52
12.2
7.8
73.55
78.60
u/l
2.07
429
3309
284
1936
2.03
13.90
8.3
6.0
1.21
1.22
mmol/l
0.79
272
1786
139
733
2.22
13.46
4.2
2.8
0.64
0.98
e6/l
1.42
84
370
77
323
2.62
12.34
1.7
3.0
67.72
67.72
g/l
0.00
71
303
25
49
5.31
12.33
1.3
1.2
—
—
—
0
0
275
1910
1.93
12.16
6.3
4.6
36.36
36.38
g/l
0.03
260
1801
215
1390
1.93
11.66
5.1
3.2
26.53
116.74
e6/l
1.12
171
1043
29
71
4.27
11.01
1.0
1.2
—
—
—
0
0
297
2173
1.86
10.63
9.2
6.8
1.21
1.21
mmol/l
0.14
269
1878
157
939
1.96
10.52
4.0
2.6
3.71
6.92
e6/l
2.47
147
857
125
694
2.05
10.30
2.0
1.9
—
—
—
0
0
288
2100
1.83
10.29
3.7
2.5
75.68
76.13
nmol/l
0.10
274
1912
117
638
2.08
10.11
4.2
2.3
132.82
120.01
ug/g
0.20
95
505
187
1199
1.87
10.08
4.8
3.0
0.14
0.36
e6/l
2.85
138
855
58
235
2.65
9.92
1.6
1.5
—
—
—
0
0
96
495
2.15
9.56
2.0
1.9
—
—
—
0
0
98
514
2.12
9.33
1.9
1.8
—
—
—
0
0
198
1324
1.80
9.12
6.5
3.6
0.00
0.01
estimate
0.69
64
488
67
303
2.39
9.10
1.4
1.6
—
—
—
0
0
20
27
7.66
9.01
1.2
1.1
—
—
—
0
0
234
1663
1.74
8.61
4.3
3.4
33.35
66.64
ng/l
0.41
158
1093
330
2589
1.75
8.44
6.1
4.6
6.40
6.55
mmol/l
0.79
319
2438
163
1054
1.80
8.25
1.7
1.4
2.46
2.25
g/l
0.69
109
662
199
1364
1.74
8.24
2.5
2.1
211.09
170.94
u/l
0.20
192
1297
19
28
7.00
8.13
1.3
1.2
—
—
—
0
0
477
4267
2.43
7.49
6.4
5.5
1.88
1.84
mu/l
0.16
451
3983
100
573
1.92
7.35
7.5
6.7
104.68
104.20
mmol/l
0.52
100
573
32
111
3.01
7.30
2.4
1.5
7364.15
13371.84
e6/l
0.51
26
82
497
4544
3.12
7.26
24.9
13.8
17.77
22.56
mg/l
4.15
445
3677
169
1140
1.71
7.22
2.9
2.2
2.60
2.92
mg/l
1.17
157
988
257
1943
1.64
7.04
15.7
10.3
1.16
1.17
inr
0.17
213
1588
250
1879
1.64
6.99
6.1
3.3
0.00
0.01
estimate
0.78
54
423
112
678
1.83
6.91
4.2
2.9
4.53
3.22
e6/l
0.31
52
316
173
1189
1.68
6.83
3.5
3.1
858.44
964.41
ng/l
0.25
148
994
160
1077
1.70
6.83
2.0
1.7
0.83
1.05
mg/l
0.96
124
838
12
11
11.13
6.82
1.0
1.0
—
—
—
0
0
38
152
2.62
6.68
1.4
1.3
—
—
—
0
0
30
106
2.94
6.64
1.1
1.1
2.32
3.58
e6/l
0.61
22
79
169
1166
1.67
6.53
3.5
2.6
338.08
332.29
umol/l
0.34
157
1050
297
2360
1.60
6.40
3.8
3.0
110.50
102.04
ug/l
0.47
282
2226
30
109
2.86
6.33
1.1
1.2
77.43
139.56
e6/l
0.40
23
85
81
454
1.93
6.32
4.7
4.6
245.37
240.58
u/l
0.08
76
439
210
1542
1.61
6.27
2.7
3.5
2.36
2.35
mmol/l
0.04
190
1407
30
110
2.83
6.22
2.6
3.0
1.63
2.48
index
0.35
19
59
28
99
2.93
6.20
1.5
1.2
274.07
216.11
u/ml
0.52
19
53
161
1111
1.65
6.16
2.4
2.2
—
—
—
0
0
148
1001
1.67
6.11
1.8
1.6
—
—
—
0
0
29
106
2.84
6.06
2.3
1.3
—
—
—
0
0
104
640
1.78
6.03
2.3
1.9
29.17
29.35
s
0.13
104
626
35
143
2.55
5.91
1.2
1.3
—
—
—
0
0
299
2408
1.57
5.86
6.5
6.4
9.71
10.89
umol/l
1.91
290
2294
197
1449
1.58
5.72
3.3
2.5
54.86
64.38
u/l
1.45
181
1348
32
128
2.60
5.65
1.1
1.3
371.72
456.33
mg/l
1.43
32
122
417
3653
1.71
5.63
5.4
4.5
14.78
14.59
pmol/l
0.93
391
3388
58
303
2.03
5.52
2.6
2.4
4.37
6.40
ug/l
1.30
51
275
23
78
3.04
5.48
1.3
1.2
8.80
2.60
u/ml
—
5
25
47
228
2.17
5.42
4.5
2.3
0.68
0.60
%
1.06
47
228
246
1928
1.52
5.24
2.4
2.0
98.74
96.34
pmol/l
0.29
132
1022
123
825
1.64
5.15
2.3
2.7
2.45
2.44
mmol/l
0.40
108
743
9
9
10.15
5.04
1.0
1.1
107.00
106.78
%
—
9
9
50
256
2.05
5.03
8.3
9.7
0.70
0.62
%
0.72
50
256
176
1292
1.55
5.02
1.7
1.6
18.91
21.03
nmol/l
1.12
160
1108
24
88
2.81
5.01
1.7
1.3
148.63
165.28
au/ml
—
8
30
164
1186
1.56
5.00
1.4
1.3
1.18
1.80
u/ml
0.64
38
358
365
3135
1.55
4.91
3.3
3.3
—
—
—
0
0
25
95
2.71
4.89
1.4
1.5
—
—
—
0
0
14
29
4.93
4.84
2.0
1.6
0.88
0.66
e9/l
0.75
14
29
97
624
1.68
4.75
1.7
1.7
1342.00
1205.81
nmol/l
0.61
79
468
28
115
2.52
4.71
1.1
1.2
3.88
3.73
mmol/l
0.28
28
108
64
366
1.85
4.69
2.3
2.3
69.63
67.58
ml/min/173m2
0.13
27
149
492
4599
2.30
4.61
23.7
15.8
3.94
3.95
mmol/l
0.48
487
4494
491
4589
2.25
4.54
23.4
15.7
139.68
139.74
mmol/l
0.21
486
4498
13
27
4.91
4.52
4.9
3.4
1627.31
930.07
mg
0.58
13
27
13
27
4.91
4.52
1.0
1.1
1503.23
1517.70
miu/ml
0.02
13
27
60
342
1.85
4.44
1.8
2.0
—
—
—
0
0
13
28
4.73
4.39
1.0
1.0
—
—
—
0
0
7
6
11.80
4.28
3.0
2.0
1.68
1.34
ratio
—
7
6
21
79
2.73
4.21
1.3
1.2
6.00
6.29
u/ml
—
5
35
12
25
4.89
4.21
2.6
2.2
—
—
—
0
0
506
4810
2.93
4.18
19.5
11.2
26.41
26.42
u/l
0.00
498
4698
25
106
2.43
3.97
4.4
4.3
3.87
3.83
mmol/l
0.14
25
106
116
817
1.54
3.87
4.1
3.5
476.49
395.23
ng/l
0.07
82
571
51
289
1.85
3.86
1.5
1.9
—
—
—
0
0
69
428
1.71
3.85
3.8
2.3
26.48
35.51
u/l
1.81
58
364
30
140
2.21
3.85
3.0
2.9
—
—
—
0
0
143
1057
1.49
3.79
7.4
3.4
1.02
1.02
kg/l
0.06
97
702
72
455
1.68
3.76
2.1
2.0
340.52
383.52
nmol/l
1.21
66
431
34
169
2.08
3.74
3.3
2.1
1.80
1.50
g/l
0.60
28
148
21
87
2.47
3.51
1.3
1.5
—
—
—
0
0
14
47
3.03
3.43
1.4
1.9
—
—
—
0
0
15
53
2.88
3.38
1.7
2.1
12.71
21.67
mg/l
—
7
26
19
77
2.52
3.33
2.9
3.0
—
895.43
—
0
7
7
11
6.43
3.19
1.7
2.6
0.63
0.60
mmol/l
—
7
11
21
92
2.34
3.14
1.5
1.7
—
—
—
0
0
18
75
2.45
3.00
1.5
2.0
—
—
—
0
0
29
149
2.00
2.96
2.4
2.4
24.33
25.27
mmol/l
0.95
29
149
11
32
3.49
2.91
1.0
1.8
—
—
—
0
0
24
116
2.12
2.87
1.2
1.2
—
—
—
0
0
24
117
2.10
2.81
5.1
3.9
1.47
2.19
ratio
0.66
14
71
43
256
1.74
2.81
5.5
3.0
127.74
130.71
g/l
0.43
43
250
15
59
2.59
2.81
1.3
1.3
—
—
—
0
0
15
59
2.59
2.81
1.3
1.3
—
—
—
0
0
15
59
2.59
2.81
1.3
1.3
—
—
—
0
0
10
28
3.62
2.79
1.0
1.1
—
—
—
0
0
32
174
1.89
2.79
1.7
1.6
9.16
7.76
u/ml
—
10
36
458
4292
1.56
2.78
6.8
5.8
38.92
38.68
mmol/mol
0.23
439
4067
49
305
1.67
2.74
2.7
3.9
4.28
4.56
pmol/l
1.30
39
271
10
29
3.50
2.70
1.0
1.1
1.09
1.12
u/l
—
5
14
8
19
4.26
2.68
1.0
1.0
—
—
—
0
0
72
495
1.53
2.67
9.8
6.1
—
—
—
0
0
11
36
3.10
2.58
1.2
1.2
112.09
115.64
pmol/l
0.08
11
36
12
42
2.90
2.56
1.5
2.0
—
—
—
0
0
5
7
7.20
2.55
1.0
1.0
—
—
—
0
0
14
56
2.54
2.55
1.3
1.3
—
—
—
0
0
14
56
2.54
2.55
1.3
1.3
—
—
—
0
0
469
4436
1.58
2.53
21.1
13.2
83.67
84.82
ml/min/173m2
0.59
449
4070
14
57
2.50
2.47
1.3
1.3
—
—
—
0
0
38
228
1.72
2.44
2.6
2.9
1.19
1.89
mmol/l
0.62
30
168
32
183
1.80
2.42
1.4
1.6
—
—
—
0
0
5
8
6.30
2.37
1.0
1.3
—
—
—
0
0
13
52
2.54
2.37
1.0
1.1
—
—
—
0
0
18
84
2.18
2.37
1.6
1.3
—
—
—
0
0
18
84
2.18
2.37
1.6
1.3
—
—
—
0
0
200
1677
1.31
2.33
2.9
3.2
37.62
31.66
u/l
0.42
189
1589
65
451
1.50
2.32
7.6
8.0
0.41
0.93
mmol/l
0.62
59
385
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
28
3.25
2.31
1.0
1.1
—
—
—
0
0
9
28
3.25
2.31
1.2
1.1
—
—
—
0
0
24
127
1.93
2.30
1.6
1.4
251.42
300.52
ug/g
0.44
12
75
185
1537
1.32
2.30
4.3
3.3
7.81
7.62
mmol/l
0.22
164
1317
10
34
2.98
2.29
3.0
4.6
—
—
—
0
0
7
18
3.93
2.26
1.0
1.5
—
—
—
0
0
25
136
1.88
2.22
2.9
2.0
187.80
244.33
ug/l
0.19
20
126
5
9
5.60
2.22
1.0
2.8
—
—
—
0
0
7
19
3.72
2.15
1.3
2.0
—
—
—
0
0
26
145
1.83
2.14
1.2
1.3
—
—
—
0
0
13
55
2.40
2.13
1.0
1.1
—
—
—
0
0
25
138
1.85
2.13
1.4
1.6
—
—
—
0
0
462
4386
1.48
2.10
5.6
4.8
5.78
5.85
mmol/l
0.60
447
4085
16
75
2.17
2.10
1.1
1.1
—
—
—
0
0
173
1440
1.30
2.09
5.1
4.1
19.63
9.34
mg/mmol
1.12
120
886
13
56
2.36
2.06
1.5
1.8
—
—
—
0
0
22
118
1.90
2.04
1.5
1.8
—
—
—
0
0
5
11
4.58
1.94
1.4
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
18
92
1.99
1.92
2.1
2.6
0.35
0.34
iu/ml
—
10
48
363
3343
1.28
1.86
3.5
3.2
43.55
44.19
u/l
0.06
349
3177
21
115
1.86
1.85
1.5
1.7
—
—
—
0
0
244
2145
1.26
1.85
3.0
2.7
—
—
estimate
—
0
0
6
17
3.56
1.84
1.0
1.1
—
—
—
0
0
6
17
3.56
1.84
3.3
5.9
—
—
—
0
0
20
108
1.89
1.84
1.4
1.5
—
—
—
0
0
18
94
1.95
1.82
1.6
2.0
138.18
130.05
g/l
0.51
11
76
6
18
3.36
1.75
1.5
1.9
1.31
1.00
nmol/l
—
6
13
509
4971
2.13
1.75
36.2
21.4
91.21
90.87
fl
0.92
509
4929
166
1402
1.27
1.75
5.1
3.0
0.04
0.07
estimate
0.20
55
417
509
4972
2.12
1.73
36.9
21.8
48.61
40.55
%
0.51
509
4927
509
4974
2.10
1.69
36.6
21.6
135.11
135.68
g/l
0.44
509
4929
6
19
3.18
1.66
1.3
1.1
—
—
—
0
0
10
41
2.47
1.65
1.4
1.6
—
—
—
0
0
10
41
2.47
1.65
1.4
1.6
—
—
—
0
0
10
41
2.47
1.65
1.4
1.6
—
—
—
0
0
24
143
1.71
1.64
2.7
3.3
24.70
25.03
mmol/l
0.23
24
137
10
42
2.41
1.62
1.3
1.2
59.50
53.10
u/l
—
10
37
10
42
2.41
1.62
1.5
1.1
—
—
—
0
0
17
91
1.90
1.62
2.0
1.5
—
—
—
0
0
5
14
3.60
1.62
1.6
3.0
117.00
130.64
%
—
5
14
20
114
1.78
1.58
1.1
1.1
0.47
3.05
u/ml
1.93
12
61
69
525
1.36
1.54
2.8
2.4
5.27
6.78
umol/l
1.11
58
457
13
65
2.03
1.50
1.4
1.2
—
—
—
0
0
17
95
1.82
1.44
3.7
3.0
6.04
8.41
pmol/l
1.11
17
95
24
149
1.64
1.43
1.5
1.7
—
—
—
0
0
7
29
2.43
1.39
1.1
1.1
—
—
—
0
0
80
637
1.30
1.33
1.9
2.1
—
—
—
0
0
45
328
1.41
1.31
4.2
3.9
1.24
1.23
mmol/l
0.88
38
291
9
43
2.11
1.31
1.0
1.0
—
—
—
0
0
6
24
2.52
1.30
1.3
2.0
81.77
54.70
ug/l
—
6
24
30
202
1.51
1.30
1.5
1.4
—
—
—
0
0
13
69
1.91
1.29
1.5
1.3
—
—
—
0
0
5
18
2.79
1.28
1.2
2.7
187.40
194.44
u/l
—
5
18
11
55
2.02
1.28
1.6
1.7
—
—
—
0
0
72
570
1.31
1.25
1.8
2.0
—
—
—
0
0
17
100
1.72
1.25
1.5
2.2
8.67
8.12
kpa
0.70
17
100
6
25
2.42
1.24
1.0
1.2
163.57
157.45
iu/ml
—
6
25
10
49
2.06
1.22
1.0
1.1
—
—
—
0
0
5
19
2.65
1.22
1.2
1.6
—
—
—
0
0
5
19
2.65
1.22
1.2
1.6
—
—
—
0
0
6
26
2.32
1.19
2.2
2.7
1.58
1.62
%
—
6
26
13
73
1.80
1.11
1.5
1.5
—
—
—
0
0
29
203
1.45
1.08
1.8
1.9
2653.95
4236.94
u/l
—
6
80
15
90
1.69
1.05
1.1
1.1
4.73
1.52
eliau/ml
—
6
42
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
23
2.18
0.98
1.6
2.2
109.60
119.48
%
—
5
23
474
4613
1.31
0.98
6.3
5.5
2.83
2.80
mmol/l
0.34
453
4347
449
4343
1.25
0.96
4.7
4.1
1.39
1.29
mmol/l
2.46
425
4054
15
93
1.63
0.94
1.5
1.5
—
—
—
0
0
20
134
1.51
0.93
1.2
1.2
—
—
—
0
0
20
134
1.51
0.93
1.2
1.2
—
—
—
0
0
14
214
0.64
0.84
1.0
1.1
1.01
0.91
g/l
0.78
14
214
8
45
1.79
0.84
1.4
1.8
—
—
—
0
0
12
73
1.66
0.82
1.1
1.0
0.18
0.52
u/ml
—
5
19
102
887
1.19
0.80
1.8
1.6
92222664.33
51444008.48
pmol/l
0.17
90
762
46
368
1.27
0.79
1.6
1.5
—
—
—
0
0
218
2013
1.14
0.78
2.1
1.9
1.45
1.37
mmol/l
0.69
183
1737
65
543
1.23
0.77
4.4
4.6
30.48
31.68
%
0.39
48
350
14
209
0.66
0.77
1.0
1.1
1.51
1.55
g/l
0.18
14
209
6
34
1.77
0.76
1.5
1.5
—
—
—
0
0
9
53
1.71
0.75
1.6
1.2
—
—
—
0
0
30
231
1.32
0.69
2.0
1.5
—
—
—
0
0
5
27
1.86
0.68
1.8
1.4
—
—
—
0
0
7
44
1.60
0.65
1.1
1.4
—
—
—
0
0
8
51
1.58
0.60
1.3
1.2
—
—
—
0
0
90
798
1.15
0.58
4.0
4.2
25.90
21.88
%
1.60
43
340
40
330
1.23
0.56
2.6
2.4
13.94
13.38
nmol/l
0.15
35
308
466
4572
1.19
0.54
5.7
4.9
4.75
4.75
mmol/l
0.03
445
4320
69
605
1.16
0.52
2.9
2.9
0.79
0.73
ug/l
0.30
43
347
24
189
1.28
0.50
1.3
1.6
—
—
—
0
0
6
41
1.47
0.50
1.0
1.1
—
—
—
0
0
6
41
1.47
0.50
1.0
1.1
—
—
—
0
0
15
110
1.37
0.49
1.3
1.8
227.27
223.13
pmol/l
0.06
15
103
40
468
0.84
0.45
1.9
1.8
3.55
3.54
mmol/l
0.01
30
341
12
163
0.73
0.44
1.5
1.5
—
—
—
0
0
5
31
1.62
0.43
1.0
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
2.2
—
—
—
0
0
15
115
1.31
0.39
2.3
1.6
—
—
—
0
0
15
115
1.31
0.39
1.2
1.2
—
—
—
0
0
49
430
1.15
0.39
4.1
4.5
3.87
19.37
ug/l
0.89
38
350
8
113
0.70
0.37
1.4
1.7
—
—
—
0
0
463
4563
1.13
0.37
5.5
4.8
1.46
1.49
mmol/l
0.72
440
4287
15
189
0.79
0.35
1.3
1.4
199.24
234.35
miu/ml
—
7
100
49
437
1.13
0.32
2.8
3.1
—
—
—
0
0
6
47
1.28
0.32
2.5
2.5
101.50
105.11
mmol/l
—
6
47
6
47
1.28
0.32
2.5
2.5
1.22
1.19
mmol/l
—
6
47
26
221
1.19
0.31
1.6
1.8
5.55
3.69
mg/l
0.65
26
169
30
261
1.16
0.28
1.4
1.4
—
—
—
0
0
6
81
0.74
0.24
1.3
1.6
62.37
47.44
ug/l
—
6
81
43
390
1.11
0.23
1.3
1.2
62.69
157.70
u/ml
2.43
19
170
5
41
1.22
0.22
1.2
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
9
78
1.16
0.15
1.8
1.6
—
—
—
0
0
12
139
0.86
0.14
1.2
1.5
1.01
0.96
ratio
—
7
89
12
139
0.86
0.14
1.2
1.5
1.27
1.12
ratio
—
7
89
12
139
0.86
0.14
1.2
1.5
1.53
1.11
ratio
—
7
89
16
141
1.14
0.14
1.4
1.8
56.50
39.33
nmol/l
0.77
16
135
8
96
0.83
0.14
1.9
1.8
—
—
—
0
0
12
138
0.87
0.13
1.2
1.5
—
—
—
0
0
62
647
0.95
0.11
1.4
1.8
1.33
1.44
%
0.93
55
578
60
626
0.95
0.10
1.9
2.0
3.37
3.48
ratio
0.29
46
501
28
262
1.07
0.09
1.2
1.0
—
—
—
0
0
6
72
0.83
0.07
1.0
1.0
—
—
—
0
0
8
78
1.03
0.07
1.4
1.6
—
—
—
0
0
9
85
1.06
0.07
3.9
3.8
20.09
3310.67
u/ml
—
9
80
29
302
0.96
0.04
2.0
2.7
17.07
47.02
u/ml
1.93
29
293
93
917
1.02
0.03
1.5
1.5
—
—
—
0
0
18
177
1.02
0.00
1.3
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.54
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
0.13
—
0
6
0
5
0.00
-0.00
0.0
11.2
—
10.98
—
0
5
0
7
0.00
-0.00
0.0
2.4
—
0.71
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
52.50
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_SCLERITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_SCLERITIS | 1.084 [0.86, 1.37] | 0.504 |
| Birth year | 1.001 [0.99, 1.01] | 0.834 |
During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 1178 females with H7_SCLERITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_SCLERITIS | 1.021 [0.79, 1.31] | 0.872 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 823 males with H7_SCLERITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_SCLERITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.093% | 0.155% |
| 5 | 0.755% | 1.052% |
| 10 | 1.801% | 2.761% |
| 15 | 3.691% | 5.513% |
| 20 | 6.633% | 9.676% |
Relationships between endpoints
↥Index endpoint: H7_SCLERITIS – Scleritis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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