No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
972 |
4. Check minimum number of eventsNone |
972 |
5. Include endpoints |
1003 |
6. Filter based on genotype QC (FinnGen only) |
894 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H49-H52
- Name in latin
- Aliae perturbationes motus binocularis
Similar endpoints
↥List of similar endpoints to
Other disorders of binocular movement
based on the number of shared cases.
Similar with more cases:
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6549 | 3902 | 2630 |
| Only index persons | 5992 | 3644 | 2348 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.07 |
| Only index persons | 0.12 | 0.13 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 26.83 | 27.34 | 25.99 |
| Only index persons | 28.28 | 28.58 | 27.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 894 | 632 | 262 |
| Unadjusted period prevalence (%) | 0.19 | 0.22 | 0.12 |
| Median age at first event (years) | 37.79 | 33.89 | 47.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 925
- Matched controls
- 9250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
307.7
550
*
H53.3
ICD-10 Finland
Other disorders of binocular vision
86.9
228.6
121
16
H50.52
ICD-10 Finland
Exophoria
107.5
203.8
105
11
H53.2
ICD-10 Finland
Diplopia
23.2
191.1
144
73
H51.2
ICD-10 Finland
Internuclear ophthalmoplegia
+∞
149.1
139
*
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
116.1
109
*
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
+∞
86.9
82
*
H50.31
ICD-10 Finland
Intermittent exotropia
+∞
71.8
68
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.9
64.3
162
387
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.6
63.0
170
429
H50.1
ICD-10 Finland
Divergent concomitant strabismus
+∞
55.8
53
*
G35
ICD-10 Finland
Multiple sclerosis
10.2
55.4
64
67
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.9
49.3
166
490
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
46.2
240
930
AA1AD
NOMESCO Finland
CT of head and brain
2.9
45.4
301
1334
TAB00
NOMESCO Finland
Lumbar puncture
5.0
42.5
98
215
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
11.8
42.5
44
39
H53.1
ICD-10 Finland
Subjective visual disturbances
4.3
40.4
114
294
XA800
NOMESCO Finland
Neuropsychological investigation
5.0
39.8
91
198
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.9
39.6
130
374
109
Kela drug reimbursment
Multiple sclerosis
9.8
39.2
46
49
R51.80
ICD-10 Finland
Headache
2.8
38.4
260
1151
XCK00
NOMESCO Finland
Perimetry
5.1
37.9
83
174
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
36.5
192
741
H50.2
ICD-10 Finland
Vertical strabismus
187.1
35.0
36
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.8
34.4
65
119
H51.0
ICD-10 Finland
Palsy of conjugate gaze
+∞
33.5
32
*
WX704
NOMESCO Finland
Intubation
3.6
33.1
121
373
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
32.5
31
*
M03BX01
ATC
baclofen; systemic
6.9
30.4
48
73
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
30.4
29
*
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
9.0
30.3
38
44
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
29.3
28
*
H52.1
ICD-10 Finland
Myopia
7.2
29.1
44
64
H52.0
ICD-10 Finland
Hypermetropia
8.9
28.5
36
42
WX725
NOMESCO Finland
Noninvasive ventilation
3.9
28.5
88
241
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.6
28.1
98
292
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.6
27.6
69
161
N03AX12
ATC
[U] gabapentin; oral
2.6
27.3
180
774
3788X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other disorders of binocular eye movements
+∞
26.2
25
*
H52.5
ICD-10 Finland
Disorders of accommodation
138.9
25.7
27
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
25.6
230
1139
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
23.4
25.4
36
16
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
25.1
24
*
WX720
NOMESCO Finland
Own respiration
3.9
24.7
75
203
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.3
24.3
219
1083
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
23.6
243
1269
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
23.0
22
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.2
21.9
92
308
N03AG01
ATC
valproic acid; systemic, rectal
3.2
21.0
90
305
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.6
20.6
128
531
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.0
20.2
97
351
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
19.9
19
*
H50.8
ICD-10 Finland
Other specified strabismus
+∞
19.9
19
*
R42
ICD-10 Finland
Dizziness and giddiness
2.1
19.7
220
1177
L03AX13
ATC
glatiramer acetate; parenteral
18.2
19.7
30
17
R20.2
ICD-10 Finland
Paraesthesia of skin
2.9
19.2
97
360
XKC03
NOMESCO Finland
Water cystometry
5.0
19.1
42
88
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.0
18.5
33
57
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
6.6
18.5
30
47
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.5
18.4
45
103
N86
ICPC
Multiple sclerosis
16.6
18.4
29
18
UKC02
NOMESCO Finland
Cystoscopy
2.5
18.1
126
551
SPAT1301
SPAT
No procedures
1.9
17.9
306
1897
N28
ICPC
Limited function/disability (N)
6.9
17.5
27
40
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
5.4
17.1
34
65
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
16.7
16
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
16.5
114
495
SPAT1263
SPAT
Sampling
1.8
16.5
412
2859
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
16.4
68
225
K07.60
ICD-10 Finland
Snapping jaw
2.8
16.3
85
321
XLD10
NOMESCO Finland
Gynaecological examination
6.9
16.2
25
37
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
16.2
132
618
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.4
15.8
116
518
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.4
15.7
31
59
OAB47, ,
SPAT
2.8
15.5
83
318
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.1
15.4
68
234
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.8
15.2
82
315
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.0
14.9
43
112
N03AE01
ATC
clonazepam; systemic
3.2
14.9
62
206
WX702
NOMESCO Finland
Supraglottic ventilation device
2.9
14.8
70
250
H50.51
ICD-10 Finland
Esophoria
57.6
14.8
17
*
A02BC03
ATC
lansoprazole; oral
1.9
14.7
236
1419
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
14.6
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
14.4
380
2648
N03AX16
ATC
[U] pregabalin
1.9
14.2
199
1142
XKD06
NOMESCO Finland
Physiologic investigation of micturition
4.7
14.1
33
73
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
13.9
110
507
G51.0
ICD-10 Finland
Bell palsy
4.5
13.9
34
78
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
13.8
347
2381
A04
ICPC
Weakness/tiredness general
2.0
13.6
177
990
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
13.6
13
*
H50.9
ICD-10 Finland
Strabismus, unspecified
142.0
13.5
14
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
13.4
429
3134
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.5
13.2
84
350
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.4
13.2
33
77
L28
ICPC
Limited function/disability (L)
2.0
13.2
151
806
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
13.1
147
780
A28
ICPC
Limited function/disability NOS
2.1
13.0
128
646
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
5.7
12.9
24
43
L03AB07
ATC
interferon beta-1a; parenteral
10.7
12.8
24
23
N02BF01
ATC
gabapentin; oral
2.3
12.7
103
479
N06AX21
ATC
duloxetine; oral
2.1
12.7
130
665
SPAT1260
SPAT
Consultation of another employee
2.0
12.6
166
930
G43.9
ICD-10 Finland
Migraine, unspecified
2.3
12.6
99
455
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
12.5
111
537
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
12.3
255
1645
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.9
12.3
58
207
N06AA09
ATC
amitriptyline; systemic
2.5
12.3
82
350
H53.4
ICD-10 Finland
Visual field defects
5.2
12.3
25
49
N03AF01
ATC
carbamazepine; oral, rectal
3.1
12.2
52
175
XKD03
NOMESCO Finland
Urethral pressure profilometry
5.0
12.2
26
53
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.1
12.2
21
35
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
12.1
163
920
N03AX14
ATC
levetiracetam; systemic
3.9
12.0
35
92
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
11.9
231
1460
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
11.9
376
2715
N01
ICPC
Headache
1.9
11.8
169
973
XKD00
NOMESCO Finland
Uroflowmetry
2.3
11.6
96
451
N06AX11
ATC
mirtazapine; oral
1.7
11.6
315
2184
S06.0
ICD-10 Finland
Concussion
2.1
11.5
124
646
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
11.5
11
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
11.5
88
400
G20
ICD-10 Finland
Parkinson disease
5.0
11.3
24
49
N29
ICPC
Neurological sympt/complt other
4.7
11.2
26
57
N03AF02
ATC
oxcarbazepine; oral
3.2
11.1
45
147
H46
ICD-10 Finland
Optic neuritis
8.2
11.1
24
30
N07AA02
ATC
pyridostigmine; systemic
14.1
11.0
18
13
M35.7
ICD-10 Finland
Hypermobility syndrome
4.2
10.9
29
71
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
8.4
10.8
23
28
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
4.5
10.8
26
59
N05BA01
ATC
diazepam; systemic, rectal
2.1
10.7
115
598
M50.3
ICD-10 Finland
Other cervical disc degeneration
4.4
10.6
26
60
SPAT1324
SPAT
Screening procedure
1.8
10.5
194
1205
3503
FHL
Single muscle retroposition
+∞
10.4
10
*
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.2
10.4
95
465
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.1
10.3
43
143
WX402
NOMESCO Finland
General anaesthesia
1.7
10.3
216
1389
Z2445
NOMESCO Finland
Psychologist
2.6
10.3
60
240
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
10.2
75
334
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
10.2
209
1336
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.7
10.2
55
212
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.3
10.1
78
355
R02
ICPC
Shortness of breath/dyspnoea
2.0
10.1
126
692
WX234
NOMESCO Finland
Paracervical blockade
2.7
10.0
55
214
M79.7
ICD-10 Finland
Fibromyalgia
3.0
9.9
43
147
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.7
9.9
31
86
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
12.3
9.9
17
14
KMAK, ,
NOMESCO Finland
1.6
9.9
499
3968
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
9.9
177
1089
N03AX11
ATC
topiramate; oral
3.2
9.8
38
121
C07AA05
ATC
propranolol; systemic
1.7
9.7
206
1328
R96
ICPC
Asthma
2.1
9.5
97
494
H57.1
ICD-10 Finland
Ocular pain
2.6
9.5
54
213
U07
ICPC
Urine symptom/complaint other
2.2
9.5
81
385
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
7.6
9.4
21
28
G23.1
ICD-10 Finland
Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
101.0
9.4
10
*
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.1
9.4
91
455
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
9.4
9
*
2AB04, ,
NOMESCO Finland
21.9
9.4
13
6
G44.2
ICD-10 Finland
Tension-type headache
1.8
9.3
153
915
N05BA09
ATC
clobazam; oral
9.6
9.3
18
19
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
9.3
267
1860
N03AX09
ATC
lamotrigine; oral
2.3
9.2
69
310
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
9.2
444
3475
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
9.2
126
713
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
4.3
9.2
23
54
R1250
NOMESCO Finland
Evaluation of functional capability
3.6
9.1
30
86
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.3
9.1
73
338
N02AX02
ATC
tramadol; systemic, rectal
1.6
9.1
337
2486
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
9.1
214
1417
G70.0
ICD-10 Finland
Myasthenia gravis
18.8
8.9
13
7
R06.0
ICD-10 Finland
Dyspnoea
1.6
8.9
222
1491
SPAT1229
SPAT
Assessment of need for aid
2.6
8.9
52
209
N99
ICPC
Neurological disease other
7.3
8.8
20
28
F83
ICD-10 Finland
Mixed specific developmental disorders
7.3
8.8
20
28
R03BA05
ATC
fluticasone; inhalant
1.7
8.7
180
1149
P85
ICPC
Mental retardation
14.2
8.7
14
10
L12
ICPC
Hand/finger symptom/complaint
1.7
8.7
174
1102
N89
ICPC
Migraine
2.4
8.6
62
274
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.1
8.6
35
115
N04BB01
ATC
amantadine; oral
4.8
8.6
19
40
H02AB06
ATC
prednisolone; systemic
1.5
8.5
388
2983
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.5
8.5
53
219
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.9
8.5
40
143
B80
ICPC
Iron deficiency anaemia
3.1
8.5
35
116
XMA22
NOMESCO Finland
General examination of pregnant woman
2.1
8.5
79
389
A06AD11
ATC
lactulose; oral
2.0
8.5
101
545
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.9
8.5
24
62
F95
ICPC
Strabismus
90.9
8.4
9
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.9
8.4
38
133
164
Kela drug reimbursment
Fingolimod
12.9
8.4
14
11
N06AB04
ATC
citalopram; systemic
1.7
8.4
175
1120
WX400
NOMESCO Finland
Inhalation anesthesy
2.5
8.4
51
209
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
8.3
113
636
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
8.3
8
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
8.3
214
1444
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.4
8.3
58
253
G04BD09
ATC
trospium; oral
4.1
8.3
22
54
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
8.3
298
2175
A45
ICPC
General and Unspecified, Observ/health educat/advice/diet
3.4
8.3
29
87
R03CC03
ATC
terbutaline; systemic
2.9
8.3
39
140
K90
ICPC
Stroke/cerebrovascular accident
4.3
8.2
21
50
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
8.2
82
415
Z3231
NOMESCO Finland
Registered nurse
1.6
8.1
235
1631
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
8.1
111
627
4AA23, ,
NOMESCO Finland
33.7
8.1
10
*
A01
ICPC
Pain general/multiple sites
2.0
8.1
96
517
R52.2
ICD-10 Finland
Other chronic pain
2.7
8.1
42
159
G04BD12
ATC
mirabegron; oral
2.0
8.1
84
432
M03AX01
ATC
botulinum toxin; parenteral
3.7
8.1
25
69
SPAT1097
SPAT
Recording of ECG
1.9
8.0
103
569
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
22.2
8.0
11
5
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
22.2
8.0
11
5
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
3.9
8.0
23
60
R4110
NOMESCO Finland
Physiotherapy
1.6
8.0
226
1561
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.8
7.9
24
65
R41.3
ICD-10 Finland
Other amnesia
3.6
7.9
25
70
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
7.9
94
507
-1, ,
NOMESCO Finland
1.5
7.9
347
2639
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
7.9
74
366
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.4
7.9
53
228
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.8
7.8
23
61
JAETT, ,
NOMESCO Finland
10.9
7.8
14
13
B01AC07
ATC
dipyridamole; systemic
3.7
7.8
24
66
A02BC01
ATC
omeprazole; systemic
1.6
7.7
218
1502
L04AA27
ATC
[U] fingolimod
15.2
7.7
12
8
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
45.4
7.7
9
*
A02BC02
ATC
pantoprazole; systemic
1.5
7.7
552
4620
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.8
7.7
23
62
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
7.6
272
1975
G81.9
ICD-10 Finland
Hemiplegia, unspecified
6.8
7.6
18
27
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
7.6
124
739
A78
ICPC
Infectious disease other/NOS
3.0
7.6
33
113
H54.7
ICD-10 Finland
Unspecified visual loss
12.0
7.6
13
11
108
Kela drug reimbursment
Myasthenia gravis
25.2
7.6
10
*
CE2W4
NOMESCO Finland
Eye movement mapping
25.2
7.6
10
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
7.6
172
1123
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.9
7.5
34
119
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
7.4
169
1103
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
80.7
7.4
8
*
C03CA01
ATC
furosemide; systemic
1.7
7.4
165
1073
A03FA02
ATC
cisapride; oral, rectal
2.3
7.3
55
248
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
7.3
89
483
G43.3
ICD-10 Finland
Complicated migraine
3.2
7.3
28
89
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.5
7.3
24
69
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
7.3
7
*
H52.2
ICD-10 Finland
Astigmatism
5.9
7.2
19
33
MBA20
NOMESCO Finland
Expression of placenta
5.9
7.2
19
33
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.6
7.2
23
65
M01AB16
ATC
aceclofenac; oral
3.3
7.1
26
80
N02CC06
ATC
eletriptan; oral
2.4
7.1
47
200
M54.5
ICD-10 Finland
Low back pain
1.5
7.1
338
2596
N06AB10
ATC
escitalopram; oral
1.6
7.1
217
1519
H53.0
ICD-10 Finland
Amblyopia ex anopsia
8.0
7.1
15
19
TKC22
NOMESCO Finland
Catheterisation instruction
4.1
7.1
19
47
R03AC02
ATC
salbutamol; inhalant
1.5
7.1
510
4240
-45
ICPC
Observ/health educat/advice/diet
3.0
7.1
31
107
A02BA02
ATC
ranitidine; systemic
1.7
7.1
133
826
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
10.1
7.0
13
13
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
7.0
47
202
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.1
7.0
29
97
A02BC05
ATC
esomeprazole; systemic
1.5
7.0
322
2459
N05CF01
ATC
zopiclone; oral
1.5
7.0
236
1691
SPAT1231
SPAT
Assessment of adjustments needed in living environment
5.5
6.9
19
35
C07AB07
ATC
bisoprolol; oral
1.5
6.9
313
2379
N05CD07
ATC
temazepam; oral
2.0
6.9
71
363
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
6.9
165
1090
R3120
NOMESCO Finland
Training in mobility skills
13.9
6.9
11
8
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.9
240
1729
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.5
6.9
43
179
J01DA09
ATC
[U] cefadroxil
1.5
6.9
225
1600
M48.0
ICD-10 Finland
Spinal stenosis
1.9
6.9
82
443
N02CC03
ATC
zolmitriptan; nasal, oral
2.1
6.8
65
323
R13
ICD-10 Finland
Dysphagia
2.1
6.8
61
296
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
3.8
6.8
20
53
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
6.8
75
394
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.4
6.8
47
205
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.8
144
923
RS222, ,
NOMESCO Finland
4.3
6.8
17
40
H50.50
ICD-10 Finland
Alternating hyperphoria
40.4
6.8
8
*
G36.9
ICD-10 Finland
Acute disseminated demyelination, unspecified
16.8
6.8
10
6
RS142, ,
NOMESCO Finland
16.8
6.8
10
6
N03AX22
ATC
perampanel; oral
22.7
6.7
9
*
183
Kela drug reimbursment
Lamotrigin and topiramate
5.5
6.6
18
33
CS494
NOMESCO Finland
Other visual field testing
3.5
6.6
22
64
353
Kela drug reimbursment
Cladribine and fingolimod
12.4
6.6
11
9
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
6.6
167
1119
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
8.8
6.6
13
15
N05AH04
ATC
quetiapine; oral
1.6
6.5
177
1204
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.0
6.5
65
329
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.9
6.5
84
466
SAA04
NOMESCO Finland
Special examination of mouth
2.1
6.5
59
289
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
3.4
6.4
22
65
181
Kela drug reimbursment
Retigabine and vigabatrin
70.3
6.4
7
*
N02CC05
ATC
almotriptan; oral
2.3
6.4
49
223
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
7.5
6.4
14
19
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
6.4
116
712
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
14.4
6.4
10
7
H02.2
ICD-10 Finland
Lagophthalmos
14.4
6.4
10
7
X01
ICPC
Genital pain female
4.1
6.4
17
42
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.7
6.4
34
131
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
6.6
6.3
15
23
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
6.3
52
244
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
6.3
496
4153
XQ855, ,
SPAT
5.2
6.3
18
35
SPAT1050
SPAT
Extensive neurological examination
3.2
6.3
24
76
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
9.3
6.3
12
13
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.1
6.3
55
265
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.0
6.3
65
334
L03AB08
ATC
interferon beta-1b; parenteral
18.2
6.3
9
5
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
6.3
6
*
3507
FHL
Retroposition and resection
+∞
6.3
6
*
G80.8
ICD-10 Finland
Other cerebral palsy
+∞
6.3
6
*
0148, ,
NOMESCO Finland
+∞
6.3
6
*
3789X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Unspecified disorder of eye movements
+∞
6.3
6
*
J01DA01
ATC
[U] cefalexin
1.4
6.3
516
4357
F02.89*G35
ICD-10 Finland
Dementia in multiple sclerosis
26.9
6.2
8
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
6.2
47
213
J01EA01
ATC
trimethoprim; systemic
1.5
6.2
216
1551
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.8
6.2
87
495
N87
ICPC
Parkinsonism
6.3
6.2
15
24
HAMTE, ,
NOMESCO Finland
5.4
6.2
17
32
PA7BD
NOMESCO Finland
CT angiography of neck and brain
5.8
6.2
16
28
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
6.1
178
1230
SPAT1101
SPAT
Orthostatic test
2.8
6.1
29
105
ZXA10
NOMESCO Finland
Bilateral
1.6
6.0
133
860
N05BA04
ATC
oxazepam; oral
1.5
6.0
221
1604
-, ,
ICD-10 Finland
3.5
6.0
20
58
N05CD08
ATC
midazolam; nasal, systemic
3.5
6.0
20
58
L04AX01
ATC
azathioprine; systemic
2.4
6.0
38
159
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
6.0
75
411
F05
ICPC
Visual disturbance other
2.6
6.0
34
135
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
395
2062
2.60
42.53
2.5
2.0
185.00
183.51
u/l
0.01
380
1964
48
51
9.87
40.96
1.2
1.1
1.18
0.11
nmol/l
—
14
8
90
197
4.95
39.10
1.6
1.6
1868.11
677.27
e6/l
0.29
72
150
88
194
4.91
37.89
1.6
1.6
172.14
18.19
e6/l
0.50
66
140
87
192
4.90
37.40
1.3
1.6
3.47
3.65
mmol/l
1.07
81
182
56
84
7.03
36.02
1.1
1.0
—
—
—
0
0
56
89
6.63
34.11
1.1
1.0
—
—
—
0
0
51
78
6.86
32.19
1.2
1.2
35.83
41.21
mg/l
0.31
42
62
49
73
7.03
31.68
1.1
1.1
219.34
240.71
mg/l
0.30
44
62
45
62
7.58
31.18
1.2
1.2
0.77
0.64
ratio
0.32
25
35
50
81
6.47
29.87
1.1
1.1
—
—
—
0
0
226
1070
2.47
28.09
2.3
2.3
28.39
29.47
s
2.61
216
1039
45
70
6.71
27.93
1.1
1.1
—
—
—
0
0
473
3090
2.09
26.19
5.5
4.7
36.84
36.72
g/l
0.20
451
2926
39
58
6.98
25.22
1.1
1.1
0.98
1.09
u/l
0.66
16
26
115
418
3.00
23.80
3.0
3.1
154.59
162.59
ng/l
0.07
109
373
42
72
6.06
23.71
1.9
1.3
—
—
—
0
0
324
1957
2.01
21.11
4.4
3.4
1.02
1.02
kg/l
1.88
219
1284
596
4427
1.97
21.00
7.1
4.9
6.26
6.45
mmol/l
1.73
534
4064
504
3548
1.92
20.76
9.8
6.8
1.21
1.21
mmol/l
0.26
454
3102
150
669
2.48
20.73
2.9
2.8
10.31
10.39
g/l
0.10
138
623
458
3164
1.89
19.59
8.6
6.4
1.21
1.21
mmol/l
0.28
438
2950
95
358
2.84
18.31
8.0
11.3
16.66
15.95
%
1.67
90
341
169
838
2.24
18.20
2.2
1.8
—
—
—
0
0
234
1328
2.02
17.68
4.2
3.6
75.48
453.58
ng/l
3.35
152
872
161
804
2.21
16.97
2.3
1.8
—
—
—
0
0
360
2384
1.84
16.91
3.3
2.5
61.05
61.09
u/l
0.00
338
2227
664
5350
1.85
15.59
6.3
4.2
66.29
1024.52
e6/l
—
7
63
92
372
2.64
15.45
6.8
7.7
23.81
24.21
mmol/l
0.53
86
351
124
590
2.27
14.59
8.0
9.2
123.05
121.49
g/l
0.38
119
577
139
699
2.16
14.27
7.7
9.1
0.95
0.78
mmol/l
0.22
104
577
141
714
2.15
14.22
7.7
8.9
13.07
12.75
kpa
0.29
133
685
141
714
2.15
14.22
7.7
8.9
4.91
5.10
kpa
1.68
132
684
179
996
1.99
13.98
1.7
1.7
1092.73
1164.41
nmol/l
0.51
143
773
414
2997
1.69
13.37
13.6
10.2
1.15
1.16
inr
0.15
354
2465
391
2793
1.69
13.24
4.1
3.2
27.42
30.34
u/l
1.21
368
2644
563
4440
1.68
12.96
4.6
3.5
0.00
3.08
estimate
0.80
90
945
25
27
9.48
12.53
2.1
1.3
—
—
—
0
0
163
910
1.96
12.52
5.2
6.2
1.06
1.08
mmol/l
0.45
155
846
192
1135
1.87
12.40
2.3
1.9
—
—
—
0
0
195
1170
1.84
11.98
3.4
3.5
0.83
0.82
mmol/l
0.65
186
1123
583
4712
1.64
11.53
11.3
9.0
4.02
4.02
e9/l
0.01
529
4107
102
495
2.19
11.38
2.1
1.7
—
—
—
0
0
21
38
5.63
11.21
1.2
1.1
—
—
—
0
0
555
4468
1.61
10.83
4.6
3.5
0.03
0.35
estimate
0.45
88
895
412
3132
1.57
9.99
2.2
2.0
96.38
96.30
pmol/l
0.01
218
1697
492
3896
1.56
9.94
6.5
6.1
9.75
10.99
umol/l
2.91
470
3708
286
2012
1.61
9.57
1.7
1.6
21.94
20.22
nmol/l
1.01
262
1753
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
21
44
4.86
9.57
1.3
1.1
—
—
—
0
0
854
7822
2.20
9.53
21.9
14.2
139.78
139.59
mmol/l
1.75
844
7663
682
5852
1.63
9.51
4.6
4.0
10.10
10.10
mm/h
0.00
657
5508
540
4404
1.54
9.28
4.6
3.5
0.00
0.00
estimate
0.50
88
938
674
5785
1.61
9.20
8.5
7.4
78.98
77.55
u/l
0.26
644
5499
853
7832
2.14
9.09
22.0
14.3
3.92
3.93
mmol/l
0.55
842
7656
46
174
2.73
8.83
1.2
1.1
—
—
—
0
0
105
568
1.96
8.73
2.5
2.4
9.20
18.91
au/ml
—
9
64
17
19
9.09
8.55
6.1
2.8
—
—
—
0
0
141
852
1.77
8.27
2.3
2.1
379.91
384.53
nmol/l
0.10
130
798
288
2111
1.53
7.77
2.6
2.2
2.41
2.69
mg/l
1.37
262
1832
25
72
3.54
7.58
2.8
3.0
—
—
—
0
0
95
522
1.91
7.54
4.3
4.0
82.94
72.68
ng/l
0.51
85
477
70
347
2.10
7.41
1.3
2.2
34.58
40.42
u/l
1.96
65
315
119
717
1.76
7.02
8.0
4.6
2.01
1.67
mmol/l
0.63
109
613
418
3361
1.44
6.88
4.5
3.3
0.05
0.03
estimate
0.26
75
798
178
1206
1.59
6.70
2.4
2.3
13.15
14.12
umol/l
1.15
171
1125
734
6593
1.55
6.65
5.6
4.5
14.61
14.48
pmol/l
0.76
702
6144
467
3869
1.42
6.34
3.4
2.7
—
—
estimate
—
0
0
85
488
1.82
5.90
2.8
2.6
66.63
67.14
g/l
0.29
79
459
649
5737
1.44
5.90
3.9
3.1
35.93
38.45
u/l
0.49
620
5503
30
113
2.71
5.87
1.4
1.3
—
—
—
0
0
163
1116
1.56
5.82
2.4
2.3
2.47
2.39
g/l
0.95
157
1029
103
634
1.70
5.63
8.7
4.1
4.72
4.65
kpa
0.13
103
614
85
496
1.79
5.60
1.8
1.6
—
—
—
0
0
385
3135
1.39
5.53
1.9
1.9
1.39
1.33
mmol/l
0.79
361
2725
319
2516
1.41
5.53
3.3
3.2
2.33
2.35
mmol/l
2.26
297
2333
303
2382
1.40
5.31
1.4
1.4
0.53
2.01
u/ml
4.69
76
670
56
291
1.98
5.27
2.4
2.2
1.98
4.00
iu/l
3.07
31
119
320
2558
1.38
5.03
3.6
2.9
0.04
0.05
estimate
0.07
77
787
813
7594
1.58
4.94
6.7
5.3
1.71
1.81
mu/l
2.15
787
7192
194
1427
1.45
4.86
1.8
1.6
438.73
20870689.19
pmol/l
1.32
168
1241
520
4507
1.35
4.79
3.9
3.2
86.68
87.14
ug/l
0.02
498
4276
15
34
4.47
4.76
1.3
1.1
—
—
—
0
0
88
545
1.68
4.72
1.5
1.4
—
—
—
0
0
11
18
6.17
4.61
1.0
1.1
—
—
—
0
0
875
8354
1.88
4.60
22.6
15.6
70.54
71.23
umol/l
0.25
870
8266
143
1002
1.51
4.56
2.4
2.4
21.85
23.61
%
0.86
137
942
94
601
1.63
4.47
3.2
3.7
4.58
4.65
pmol/l
0.32
83
545
106
700
1.58
4.41
8.0
5.8
—
—
—
0
0
430
3655
1.33
4.36
2.8
2.5
75.79
74.13
nmol/l
0.60
395
3391
214
1640
1.40
4.23
1.4
1.3
17.60
30.24
iu/ml
2.23
61
465
843
8003
1.60
4.06
19.6
13.0
20.83
20.91
mg/l
0.02
693
6445
175
1307
1.42
4.00
2.3
2.5
69.48
99.69
ug/g
1.56
134
1021
196
1494
1.40
3.98
1.3
1.3
1.72
10.52
u/ml
6.61
69
613
871
8343
1.75
3.97
13.3
10.3
24.81
25.52
u/l
0.75
854
8146
108
735
1.53
3.95
3.4
2.3
5089.42
5760.53
u/l
0.10
48
322
86
556
1.60
3.93
1.8
1.7
285.31
301.78
mu/l
0.17
81
495
32
152
2.14
3.88
3.0
3.4
1.41
1.80
ratio
0.34
18
86
34
166
2.09
3.85
1.8
2.0
—
—
—
0
0
59
347
1.75
3.85
11.3
3.5
0.63
0.62
%
0.12
59
347
31
146
2.16
3.84
2.3
1.9
13.68
13.08
%
0.98
31
146
51
289
1.81
3.77
1.5
1.6
190.92
0.28
iu/ml
0.47
11
40
96
645
1.54
3.72
2.1
2.7
0.22
0.22
g/l
0.03
90
607
14
40
3.54
3.61
1.9
4.4
94.00
140.96
umol/l
—
6
23
100
684
1.52
3.58
1.4
1.3
149.40
240.41
u/ml
0.89
88
640
65
404
1.65
3.49
1.6
1.6
54.95
57.51
ug/l
0.19
65
404
234
1871
1.34
3.48
1.6
1.6
—
—
—
0
0
24
106
2.30
3.48
1.3
1.6
18.74
25.45
ng/l
1.15
24
106
238
1913
1.33
3.40
4.7
4.0
94.50
92.96
%
0.49
229
1866
8
14
5.75
3.34
1.1
1.1
—
—
—
0
0
144
1072
1.41
3.34
2.2
1.9
—
—
—
0
0
235
1895
1.32
3.27
2.3
2.0
0.80
1.11
mg/l
2.27
186
1461
59
364
1.66
3.27
1.3
1.2
0.18
1.35
u/ml
—
9
23
8
15
5.37
3.19
1.1
1.1
—
—
—
0
0
41
231
1.81
3.13
1.3
1.6
—
—
—
0
0
52
316
1.68
3.07
5.1
3.5
48.16
49.89
%
0.20
52
308
165
1277
1.36
3.02
2.4
2.1
—
—
—
0
0
259
2147
1.29
2.90
4.2
3.0
0.21
0.31
e6/l
1.17
189
1512
24
115
2.12
2.90
1.2
1.6
—
—
—
0
0
14
52
2.72
2.89
1.3
1.1
1733.71
1570.58
miu/ml
0.16
14
52
10
27
3.73
2.88
1.2
1.3
—
—
—
0
0
7
13
5.42
2.87
1.1
1.1
—
—
—
0
0
7
13
5.42
2.87
1.1
1.1
—
—
—
0
0
12
38
3.19
2.85
1.3
3.1
324.50
562.32
u/ml
1.59
12
38
68
451
1.55
2.84
1.7
1.8
—
—
—
0
0
57
363
1.61
2.83
1.6
1.9
3.49
6.58
iu/ml
—
10
89
42
247
1.73
2.80
1.7
2.2
1.35
1.32
g/l
0.07
31
221
9
23
3.94
2.78
1.4
1.1
—
—
—
0
0
9
23
3.94
2.78
1.3
1.0
—
—
—
0
0
9
23
3.94
2.78
1.3
1.0
—
—
—
0
0
33
181
1.85
2.77
1.8
1.8
177.88
197.99
pmol/l
0.50
33
169
120
897
1.39
2.73
2.9
2.9
8.17
6.85
umol/l
0.22
99
764
10
29
3.47
2.69
1.1
1.0
—
—
—
0
0
12
43
2.81
2.65
1.4
1.8
0.98
1.21
nmol/l
0.65
12
31
19
86
2.23
2.65
1.5
1.2
0.16
0.17
nmol/l
0.33
14
59
38
221
1.75
2.65
1.4
1.6
—
—
—
0
0
37
609
0.59
2.57
1.7
1.5
68.64
60.97
ug/l
0.44
32
516
12
42
2.88
2.55
2.3
3.2
81.25
137.36
nmol/l
0.70
12
42
248
2075
1.27
2.55
1.6
1.5
2.05
2.17
g/l
0.75
164
1320
163
1296
1.31
2.48
3.7
2.7
0.77
0.91
e6/l
0.33
79
633
289
2468
1.25
2.48
4.3
3.1
29.34
95.96
e6/l
1.48
223
1824
203
1665
1.28
2.44
3.5
2.5
4.18
7.18
e6/l
4.66
190
1499
8
22
3.66
2.36
1.5
1.0
—
—
—
0
0
8
22
3.66
2.36
1.5
1.1
—
—
—
0
0
31
177
1.78
2.32
4.4
6.0
168.00
423.60
iu/ml
—
5
20
96
713
1.39
2.29
1.5
1.4
29.83
22.06
iu/l
1.03
82
595
29
164
1.79
2.25
1.1
1.2
1.42
4.24
u/ml
1.07
12
55
283
2436
1.23
2.23
3.2
3.5
7.71
8.07
mmol/l
0.55
253
2122
33
195
1.72
2.22
1.2
1.4
—
—
—
0
0
42
267
1.60
2.15
1.9
1.8
37.48
40.97
nmol/l
0.46
42
260
9
30
3.02
2.15
1.0
1.0
—
—
—
0
0
9
30
3.02
2.15
2.0
1.8
20.67
16.05
umol/l
—
9
30
899
8804
1.75
2.15
29.5
20.0
4.49
4.52
e12/l
1.28
893
8652
10
36
2.80
2.14
1.0
1.0
871.00
623.42
ng/l
—
5
26
29
167
1.76
2.13
1.1
1.3
4.23
5.60
u/ml
0.29
13
68
35
554
0.62
2.11
1.6
1.5
—
—
—
0
0
767
7324
1.28
2.09
4.9
4.2
5.63
5.74
mmol/l
2.11
726
6856
36
563
0.62
2.07
1.6
1.5
1.12
1.21
ratio
0.15
22
351
36
563
0.62
2.07
1.6
1.5
1.09
0.95
ratio
0.49
21
350
36
563
0.62
2.07
1.6
1.5
1.16
1.15
ratio
0.03
21
350
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
30
177
1.72
2.04
3.2
5.0
0.39
0.34
iu/ml
0.33
15
94
28
162
1.75
2.04
1.2
1.5
—
—
—
0
0
10
38
2.65
2.01
1.5
1.3
—
—
—
0
0
10
39
2.58
1.94
1.5
1.3
—
—
—
0
0
57
398
1.46
1.94
1.4
1.5
16.07
9.34
u/l
0.44
48
317
8
27
2.98
1.94
1.1
1.4
183.88
88.53
ng/l
—
8
27
13
58
2.26
1.91
2.2
2.3
—
—
—
0
0
290
2547
1.20
1.82
4.4
3.3
16.01
78.10
ng/l
1.33
173
1505
76
568
1.37
1.79
1.1
1.1
—
—
—
0
0
35
224
1.58
1.78
1.5
1.3
236.14
324.27
ug/g
2.42
21
128
6
152
0.39
1.77
1.8
1.4
—
—
—
0
0
14
67
2.11
1.76
3.4
2.6
1.21
1.19
mmol/l
0.48
14
67
25
147
1.72
1.75
2.2
3.6
—
572.56
—
0
9
8
30
2.68
1.72
1.1
1.0
71.75
90.93
%
—
8
30
14
68
2.08
1.71
3.4
2.6
3.98
3.99
mmol/l
0.04
14
68
14
68
2.08
1.71
3.4
2.6
106.93
105.16
mmol/l
0.87
14
68
22
127
1.75
1.65
1.6
1.9
—
2160.00
—
0
7
31
197
1.59
1.64
1.5
1.2
—
—
—
0
0
27
166
1.65
1.63
1.1
1.1
—
—
—
0
0
22
128
1.74
1.61
1.2
1.3
—
—
—
0
0
22
128
1.74
1.61
1.2
1.3
—
—
—
0
0
146
1215
1.24
1.56
3.9
2.9
3.54
2.85
e6/l
0.25
62
559
94
744
1.29
1.53
2.4
2.3
58.98
101.89
u/l
0.27
82
613
169
1438
1.21
1.47
5.0
5.1
19.36
2.29
ug/l
0.95
155
1302
15
80
1.89
1.45
1.1
1.4
—
—
—
0
0
36
245
1.49
1.44
1.3
1.4
0.19
0.42
nmol/l
5.17
26
204
13
67
1.95
1.38
2.4
1.2
7.34
5.93
ug/l
0.16
13
58
27
174
1.57
1.38
2.4
2.7
1.20
1.84
index
0.42
15
95
11
54
2.05
1.33
1.5
1.1
10.73
8.26
mm/h
0.49
11
54
47
343
1.39
1.33
1.8
1.6
12.47
8.05
u/ml
0.32
18
89
11
55
2.01
1.27
1.3
1.4
28.06
26.01
umol/l
0.07
11
50
22
138
1.61
1.27
1.6
1.4
6.00
7.15
mmol/l
2.17
22
124
730
7037
1.18
1.24
5.7
5.3
37.24
37.90
mmol/mol
1.45
700
6707
15
85
1.78
1.23
1.5
1.7
—
—
—
0
0
96
786
1.25
1.22
1.2
1.3
134.83
152.41
u/ml
0.16
42
324
34
238
1.44
1.22
1.4
1.3
—
—
—
0
0
24
156
1.55
1.21
4.7
3.0
1.44
1.55
mmol/l
0.23
24
149
20
125
1.61
1.18
1.4
1.5
—
—
—
0
0
41
300
1.38
1.16
8.3
5.5
24.76
24.70
mmol/l
0.08
41
288
229
2046
1.16
1.14
3.9
4.3
9.05
8.72
mg/mmol
0.04
135
1313
8
40
2.01
1.12
1.3
1.2
283.50
483.46
u/l
—
8
35
37
268
1.40
1.12
1.1
1.2
—
37.63
—
0
11
50
381
1.33
1.11
1.4
1.7
—
—
—
0
0
34
243
1.41
1.11
3.1
1.9
0.72
2.94
ug/l
1.15
28
220
191
1687
1.17
1.10
3.2
3.3
1313.27
1037.88
ng/l
0.35
148
1409
7
31
2.27
1.10
2.3
2.6
179.57
187.48
u/l
—
7
31
37
269
1.39
1.10
7.0
5.0
9.54
8.78
kpa
2.85
37
264
7
32
2.20
1.08
1.4
1.2
184.86
94.73
nmol/l
—
7
22
31
219
1.43
1.08
1.6
1.3
232.31
227.17
u/ml
0.04
16
126
9
46
1.97
1.03
3.0
1.8
—
—
—
0
0
133
1147
1.19
1.03
1.7
1.7
1.33
1.41
%
0.98
124
1031
30
414
0.72
1.02
1.7
1.7
4.41
3.19
mg/l
0.35
25
295
55
435
1.28
0.96
2.4
2.2
4.74
7.30
ug/l
1.23
47
390
719
7399
0.87
0.95
15.0
11.9
90.75
89.78
ml/min/173m2
0.59
672
6692
7
37
1.90
0.94
2.4
3.7
0.57
0.84
index
—
7
37
258
2355
1.13
0.94
1.9
1.8
—
—
—
0
0
16
101
1.59
0.94
1.1
1.4
—
—
—
0
0
30
218
1.39
0.92
1.1
1.1
6.87
7.56
u/ml
0.08
16
97
47
369
1.29
0.88
1.9
1.5
—
—
—
0
0
13
79
1.65
0.88
1.6
1.8
—
—
—
0
0
83
697
1.21
0.88
1.5
1.4
—
—
—
0
0
11
180
0.61
0.87
1.2
1.2
—
—
—
0
0
67
552
1.23
0.85
3.6
4.4
6.58
28.64
ug/l
0.81
47
440
52
416
1.26
0.85
12.2
10.8
1.18
1.34
%
0.69
52
411
15
227
0.66
0.85
1.0
1.3
—
—
—
0
0
781
7627
1.15
0.85
4.7
4.4
4.65
4.66
mmol/l
0.10
750
7267
6
31
1.94
0.84
1.0
1.0
10.50
36.89
iu/ml
—
6
31
11
65
1.70
0.82
1.9
1.8
0.81
5.43
u/ml
—
6
21
50
402
1.26
0.80
1.4
1.5
—
—
—
0
0
49
394
1.26
0.78
1.8
1.9
—
—
—
0
0
68
808
0.83
0.77
5.2
4.0
32.27
31.73
%
0.19
51
566
11
173
0.63
0.75
1.9
1.4
—
—
—
0
0
18
124
1.46
0.75
5.3
3.2
6.46
7.60
mmol/l
2.03
18
118
5
24
2.09
0.74
1.2
1.9
—
—
—
0
0
5
24
2.09
0.74
1.2
1.9
—
—
—
0
0
5
24
2.09
0.74
1.4
1.5
—
—
—
0
0
5
25
2.01
0.72
1.2
1.8
—
—
—
0
0
9
56
1.61
0.72
1.7
1.7
—
1020574.83
—
0
6
12
77
1.57
0.68
1.0
1.1
—
—
—
0
0
12
77
1.57
0.68
1.0
1.1
—
—
—
0
0
11
69
1.60
0.68
1.0
1.1
109.64
113.20
pmol/l
0.10
11
69
7
42
1.67
0.68
2.6
2.7
59.00
48.50
umol/l
—
7
37
26
196
1.34
0.68
5.4
4.3
1.35
1.37
mmol/l
0.07
26
190
19
136
1.41
0.67
2.8
2.5
190.66
113.16
ug/min
0.21
14
79
54
449
1.22
0.66
7.0
4.8
1.27
1.63
mmol/l
0.60
43
331
78
901
0.85
0.66
1.5
1.7
3.49
3.40
mmol/l
0.31
47
615
12
78
1.55
0.65
1.0
1.2
—
—
—
0
0
24
180
1.34
0.65
1.5
1.5
—
—
—
0
0
18
246
0.73
0.63
1.6
1.3
46.58
132.09
pmol/l
1.09
18
239
12
79
1.53
0.62
1.0
1.1
—
—
—
0
0
12
79
1.53
0.62
1.0
1.3
—
—
—
0
0
12
79
1.53
0.62
1.0
1.1
—
—
—
0
0
15
104
1.45
0.62
1.2
1.5
—
—
—
0
0
10
152
0.65
0.61
3.1
3.3
26.20
26.65
mg/l
—
5
99
26
200
1.31
0.61
1.4
1.5
141.20
143.16
au/ml
—
5
59
145
1315
1.12
0.61
2.5
2.5
2.42
2.43
mmol/l
0.89
134
1176
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
127
1144
1.13
0.60
4.6
4.4
20.60
21.45
%
0.26
54
512
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
182
1969
0.91
0.57
2.3
2.3
—
—
—
0
0
39
320
1.23
0.56
1.4
1.3
—
—
—
0
0
643
6262
1.09
0.56
4.1
3.7
—
—
—
0
0
29
231
1.26
0.54
1.2
1.1
8.33
3.99
u/ml
0.37
17
113
18
237
0.75
0.52
1.6
1.7
—
—
—
0
0
9
64
1.41
0.51
1.9
2.1
-2.21
0.23
mmol/l
—
9
64
103
1140
0.89
0.50
1.8
1.8
3.69
3.42
ratio
1.14
70
851
25
198
1.27
0.50
1.2
1.3
—
—
—
0
0
7
109
0.64
0.48
1.1
1.2
20.44
14.45
u/l
—
7
92
12
85
1.42
0.47
1.0
1.1
—
—
—
0
0
772
7602
1.09
0.45
4.6
4.3
1.45
1.47
mmol/l
0.70
739
7210
45
386
1.17
0.44
2.1
1.6
—
—
—
0
0
7
51
1.38
0.44
2.3
3.5
1174.00
1137.53
mg
—
7
51
783
7718
1.09
0.43
5.3
4.8
2.74
2.76
mmol/l
0.22
752
7328
9
130
0.69
0.43
1.6
1.2
—
—
—
0
0
170
1817
0.92
0.42
2.1
2.2
—
—
—
0
0
13
96
1.36
0.41
2.2
1.7
—
—
—
0
0
5
33
1.52
0.41
2.4
2.8
2.20
1.30
%
—
5
33
0
15
0.00
0.41
0.0
5.1
—
1.20
—
0
15
5
34
1.47
0.40
1.4
1.7
—
—
—
0
0
5
34
1.47
0.40
1.4
1.7
—
—
—
0
0
5
34
1.47
0.40
1.4
1.7
—
—
—
0
0
5
34
1.47
0.40
1.4
1.7
—
—
—
0
0
37
432
0.85
0.40
1.4
1.6
0.16
0.30
mg/l
1.28
11
193
5
35
1.43
0.39
1.4
2.0
—
—
—
0
0
5
35
1.43
0.39
1.4
2.0
—
—
—
0
0
79
869
0.90
0.37
2.9
3.1
0.58
0.74
ug/l
1.89
49
528
62
690
0.89
0.36
3.9
2.9
—
—
—
0
0
6
42
1.43
0.35
1.0
1.4
—
—
—
0
0
16
126
1.27
0.35
1.1
1.3
—
190.00
—
0
8
6
44
1.37
0.34
1.2
1.3
445.00
486.08
u/l
—
6
44
21
254
0.82
0.34
1.5
1.9
—
—
—
0
0
17
137
1.25
0.32
1.9
2.6
7.78
7.23
pmol/l
0.11
17
137
728
7183
1.06
0.31
3.9
3.7
1.28
1.23
mmol/l
1.04
688
6778
7
100
0.70
0.30
2.9
3.6
39.54
3009.31
u/ml
—
7
91
27
231
1.17
0.30
1.3
1.2
—
—
—
0
0
12
93
1.29
0.30
1.0
1.1
—
—
—
0
0
7
56
1.25
0.29
1.0
1.4
—
—
—
0
0
5
74
0.67
0.26
1.0
1.0
—
—
—
0
0
245
2364
1.05
0.25
5.3
3.5
0.00
0.01
estimate
1.47
84
903
18
152
1.19
0.24
1.1
1.4
—
—
—
0
0
191
1835
1.05
0.23
2.5
2.6
302.51
324.37
umol/l
2.53
166
1653
5
39
1.28
0.23
1.0
1.3
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
16.18
58.62
u/ml
—
5
39
5
40
1.25
0.22
1.2
1.1
329.00
189.54
iu/ml
—
5
40
40
363
1.11
0.21
1.6
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
1.00
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
1.19
—
0
13
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
27
303
0.89
0.20
1.4
1.3
—
—
—
0
0
37
407
0.91
0.20
1.1
1.1
1.53
1.55
g/l
0.15
37
407
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.0
1.7
—
—
—
0
0
29
323
0.89
0.20
1.3
1.2
0.28
3.82
u/ml
5.35
19
177
26
231
1.13
0.19
1.3
1.2
—
—
—
0
0
23
204
1.13
0.18
1.2
1.1
0.09
0.36
u/ml
1.01
12
64
38
414
0.91
0.18
1.1
1.1
0.91
0.88
g/l
0.50
38
414
7
62
1.13
0.17
1.3
1.6
—
—
—
0
0
7
62
1.13
0.17
1.3
1.6
—
—
—
0
0
7
62
1.13
0.17
1.3
1.6
—
—
—
0
0
59
554
1.07
0.16
2.6
2.5
66.61
73.05
ml/min/173m2
0.75
28
220
27
244
1.11
0.16
2.8
2.5
4.68
6.06
umol/l
0.52
21
191
16
139
1.15
0.16
1.3
1.2
—
—
—
0
0
30
276
1.09
0.13
1.2
1.1
0.52
1.65
u/ml
1.03
18
127
22
241
0.91
0.12
1.4
1.6
—
—
—
0
0
31
288
1.08
0.12
1.2
1.1
3.09
6.15
u/ml
0.67
22
166
39
366
1.07
0.12
4.9
3.1
1.02
1.02
ratio
0.20
34
339
22
201
1.10
0.11
2.8
2.7
—
—
—
0
0
15
135
1.11
0.09
1.3
1.8
—
—
—
0
0
46
481
0.95
0.08
1.4
1.3
245.84
246.58
miu/ml
0.00
17
251
5
62
0.81
0.08
1.8
1.7
0.38
0.49
e9/l
—
5
62
12
108
1.11
0.07
1.3
2.2
—
—
—
0
0
109
1066
1.03
0.07
1.7
1.6
985.27
1022.58
mu/l
0.17
102
908
10
89
1.12
0.07
1.9
1.3
—
—
—
0
0
10
89
1.12
0.07
1.9
1.3
—
—
—
0
0
10
90
1.11
0.05
1.9
1.3
—
—
—
0
0
192
1944
0.98
0.05
2.6
2.1
—
—
—
0
0
56
545
1.03
0.05
1.3
1.4
—
—
—
0
0
29
278
1.04
0.04
1.3
1.1
3.61
1.68
u/ml
0.52
18
149
36
372
0.97
0.04
1.4
1.4
—
—
—
0
0
13
137
0.95
0.01
1.4
1.5
—
—
—
0
0
10
94
1.06
0.01
1.9
1.3
—
—
—
0
0
10
94
1.06
0.01
1.9
1.3
—
—
—
0
0
15
154
0.97
0.00
1.0
1.1
2.02
2.31
eliau/ml
—
8
71
12
118
1.02
0.00
1.2
1.2
—
18.00
—
0
7
14
137
1.02
0.00
1.6
1.8
—
—
—
0
0
11
105
1.05
0.00
1.1
1.1
10.38
16.40
u/ml
—
5
43
9
92
0.98
0.00
2.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
6
59
1.02
0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
6.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
6.2
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.3
—
—
—
0
0
7
77
0.91
-0.00
1.1
1.3
1.18
1.50
nmol/l
—
7
68
9
95
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
11
110
1.00
-0.00
1.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_BINOCUMOVOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_BINOCUMOVOTH | 1.212 [1.03, 1.43] | 0.023 |
| Birth year | 0.996 [0.99, 1.0] | 0.359 |
During the follow-up period (1.1.1998 — 31.12.2019), 225 out of 3488 females with H7_BINOCUMOVOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_BINOCUMOVOTH | 1.596 [1.34, 1.91] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 292 out of 2306 males with H7_BINOCUMOVOTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_BINOCUMOVOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.129% | 0.356% |
| 5 | 0.853% | 1.789% |
| 10 | 1.879% | 4.371% |
| 15 | 3.71% | 8.414% |
| 20 | 6.334% | 13.823% |
Relationships between endpoints
↥Index endpoint: H7_BINOCUMOVOTH – Other disorders of binocular movement
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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