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Tetraplegia

DOID EFO Endpoint Browser PheWeb

G6_TETRAPLE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G82.3, G82.4, G82.5
  • Hospital discharge: ICD-8 — 34403
  • Cause of death: ICD-10 — G82.3, G82.4, G82.5
  • Cause of death: ICD-8 — 34403

2 out of 7 registries used, show all original rules.

299

4. Check minimum number of events

None

299

5. Include endpoints

None

299

6. Filter based on genotype QC (FinnGen only)

274

Control definitions (FinnGen only)

Control exclude
G6_CPETAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4087 1500 2554
Only index persons 3242 1232 2010
Unadjusted period prevalence (%)
Whole population 0.06 0.04 0.07
Only index persons 0.06 0.05 0.08
Median age at first event (years)
Whole population 50.34 49.30 50.77
Only index persons 48.83 47.36 49.72

-FinnGen-

Key figures

All Female Male
Number of individuals 274 108 166
Unadjusted period prevalence (%) 0.06 0.04 0.08
Median age at first event (years) 55.15 48.20 59.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
280
Matched controls
2800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G82.5
ICD-10 Finland
Tetraplegia, unspecified
+∞
234.7
191
*
M03BX01
ATC
baclofen; systemic
105.9
208.6
110
17
G82.4
ICD-10 Finland
Spastic tetraplegia
+∞
122.0
108
*
L89
ICD-10 Finland
Decubitus ulcer and pressure area
40.4
99.7
63
20
N18
ICPC
Paralysis/weakness
36.9
94.0
61
21
XKD06
NOMESCO Finland
Physiologic investigation of micturition
24.5
94.0
72
39
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
+∞
90.7
82
*
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
22.9
77.3
60
33
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
45.7
76.1
46
12
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
37.8
66.1
42
13
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
7.8
65.8
138
309
XKC03
NOMESCO Finland
Water cystometry
23.9
64.0
48
24
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
16.4
62.4
57
43
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
12.2
61.3
69
73
R33
ICD-10 Finland
Retention of urine
8.8
59.3
92
147
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
10.1
58.8
78
103
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
7.5
55.9
106
210
R4120
NOMESCO Finland
Occupational therapy
10.0
55.5
73
95
SPAT1229
SPAT
Assessment of need for aid
9.7
51.7
69
91
L28
ICPC
Limited function/disability (L)
6.6
51.6
118
279
G82.2
ICD-10 Finland
Paraplegia, unspecified
+∞
50.6
47
*
S14.0
ICD-10 Finland
Concussion and oedema of cervical spinal cord
+∞
49.5
46
*
A28
ICPC
Limited function/disability NOS
6.3
49.0
115
277
TKC20
NOMESCO Finland
Catheterisation of bladder
8.7
46.4
68
100
N03AE01
ATC
clonazepam; systemic
10.0
45.8
58
71
SPAT1167
SPAT
Insertion of urinary catheter
13.6
44.0
44
38
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
62.4
41.0
47
9
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
433.6
39.1
38
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
5.7
37.8
89
210
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
5.5
37.6
97
248
R1250
NOMESCO Finland
Evaluation of functional capability
12.4
37.3
39
36
KA1AE
NOMESCO Finland
Kidney ultrasound examination
14.7
37.2
35
27
N30.0
ICD-10 Finland
Acute cystitis
5.7
37.0
88
209
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
5.5
36.4
90
221
S12.2
ICD-10 Finland
Fracture of other specified cervical vertebra
59.7
35.5
41
8
J01EA01
ATC
trimethoprim; systemic
4.7
34.5
117
371
UKC02
NOMESCO Finland
Cystoscopy
5.0
34.3
99
276
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
33.7
102
295
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
6.6
33.1
61
113
N03AX16
ATC
[U] pregabalin
4.5
32.6
116
379
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
40.9
31.5
39
11
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
30.6
77
190
NA1AD
NOMESCO Finland
Cervical spine CT examination
7.6
30.4
47
72
R5110, ,
SPAT
6.3
30.4
58
111
U29
ICPC
Urinary symptom/complaint other
10.7
30.4
35
37
WX408
NOMESCO Finland
General anesthesy, balanced
4.2
30.2
122
434
N03AX12
ATC
[U] gabapentin; oral
4.6
30.1
93
271
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.1
29.2
58
115
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.7
28.1
82
227
U05
ICPC
Urination problems other
7.1
28.1
46
75
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
42.7
27.8
34
9
AA1AD
NOMESCO Finland
CT of head and brain
3.9
27.6
134
535
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.8
27.0
36
46
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
8.3
27.0
38
52
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
26.4
26.9
37
16
U07
ICPC
Urine symptom/complaint other
5.7
26.1
55
115
Z43.5
ICD-10 Finland
Attention to cystostomy
64.4
25.5
29
5
J01MA12
ATC
levofloxacin; systemic
4.0
25.1
98
334
N06AX21
ATC
duloxetine; oral
5.0
25.0
63
154
J01MA02
ATC
ciprofloxacin; systemic
3.6
24.4
162
778
A06AD11
ATC
lactulose; oral
4.3
24.3
78
230
A46
ICD-10 Finland
Erysipelas
4.2
24.3
82
251
ZXD05
NOMESCO Finland
Urgent procedure
3.5
23.8
131
557
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
59.4
23.5
27
5
N99
ICPC
Neurological disease other
44.1
23.1
28
7
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
22.2
21
*
GBB00
NOMESCO Finland
Tracheostomy
47.6
21.8
26
6
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
65.3
21.2
24
*
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
40.7
21.2
26
7
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
+∞
21.1
20
*
S97
ICPC
Chronic ulcer skin
5.3
21.0
47
103
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.2
20.7
65
187
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.2
20.0
120
527
J01CA08
ATC
pivmecillinam; oral
3.2
20.0
121
534
N81
ICPC
Injury nervous system other
113.1
19.8
21
*
K59.09
ICD-10 Finland
Constipation, unspecified
5.1
19.8
46
104
J01MA06
ATC
norfloxacin; oral
4.2
19.6
61
174
N28
ICPC
Limited function/disability (N)
22.0
19.5
28
14
U04
ICPC
Incontinence urine
6.4
19.3
34
59
W17
ICD-10 Finland
Other fall from one level to another
7.0
19.3
31
49
WX872
NOMESCO Finland
Intensive care
6.0
19.1
36
67
G82.3
ICD-10 Finland
Flaccid tetraplegia
+∞
19.0
18
*
N05BA01
ATC
diazepam; systemic, rectal
3.9
19.0
66
204
R13
ICD-10 Finland
Dysphagia
5.0
18.5
44
101
Z3226
NOMESCO Finland
Physiotherapist
3.5
18.5
81
292
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.8
18.0
35
67
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
6.9
17.9
29
46
NAJ10
NOMESCO Finland
Anterior reduction of fracture of cervical spine
+∞
17.9
17
*
S14.1
ICD-10 Finland
Other and unspecified injuries of cervical spinal cord
+∞
17.9
17
*
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
6.6
17.2
29
48
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.9
17.0
122
583
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
67.6
17.0
19
*
W19
ICD-10 Finland
Unspecified fall
4.1
16.9
53
151
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
5.2
16.9
37
79
ABD40
NOMESCO Finland
Implantation of spinal injection device
+∞
16.8
16
*
U13
ICPC
Bladder symptom/complaint other
7.9
16.8
24
33
QBG10
NOMESCO Finland
Excision and repair of bedsore of trunk
95.9
16.8
18
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.2
16.5
50
139
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.4
16.5
74
269
X58
ICD-10 Finland
Exposure to other specified factors
3.4
16.0
72
262
S12.7
ICD-10 Finland
Multiple fractures of cervical spine
63.8
16.0
18
*
N02BF02
ATC
pregabalin; oral
4.7
15.9
40
96
XKD03
NOMESCO Finland
Urethral pressure profilometry
15.0
15.9
26
19
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
15.0
15.9
26
19
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.8
15.8
120
586
NF1AA
NOMESCO Finland
Hip X-ray examination
4.2
15.4
46
126
R4110
NOMESCO Finland
Physiotherapy
2.8
15.4
110
519
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.2
15.2
44
118
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
5.1
15.2
34
74
J01XX05
ATC
methenamine; oral
60.1
15.0
17
*
T91.1
ICD-10 Finland
Sequelae of fracture of spine
60.1
15.0
17
*
XG466
NOMESCO Finland
Sleep oxymetry
6.6
14.9
25
41
N30.9
ICD-10 Finland
Cystitis, unspecified
4.9
14.7
35
80
G82.1
ICD-10 Finland
Spastic paraplegia
+∞
14.7
14
*
9072A
ICD-9 Finland
Late effects of injuries to the nervous system, Late effect of spinal cord injury
+∞
14.7
14
*
Z3231
NOMESCO Finland
Registered nurse
2.8
14.7
109
522
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.7
14.6
54
172
SPAT1215
SPAT
Assessment of need for medical rehabilitation
6.4
14.6
25
42
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
18.2
14.6
22
13
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
14.5
91
399
R52.2
ICD-10 Finland
Other chronic pain
6.1
14.4
26
46
EBA15
NOMESCO Finland
Extraction of multiple teeth
6.5
14.1
24
40
JDB10
NOMESCO Finland
Percutaneous gastrostomy
21.4
14.0
20
10
NAG41
NOMESCO Finland
Anterior fusion of cervical spine with fixation
56.3
14.0
16
*
Y86
ICD-10 Finland
Sequelae of other accidents
56.3
14.0
16
*
U71
ICPC
Cystitis/urinary infection other
5.4
13.9
29
59
TAB00
NOMESCO Finland
Lumbar puncture
5.1
13.9
31
67
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.6
13.9
35
84
A41.9
ICD-10 Finland
Sepsis, unspecified
5.6
13.7
27
52
G04BD08
ATC
solifenacin; oral
4.4
13.7
37
94
G82.0
ICD-10 Finland
Flaccid paraplegia
+∞
13.6
13
*
QBG00
NOMESCO Finland
Debridement of bedsore of trunk
146.8
13.6
14
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
13.5
61
221
X59
ICD-10 Finland
Exposure to unspecified factor
2.9
13.4
82
352
M48.0
ICD-10 Finland
Spinal stenosis
3.3
13.0
56
196
J96.1
ICD-10 Finland
Chronic respiratory failure
11.3
13.0
24
23
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.4
13.0
52
174
T90.5
ICD-10 Finland
Sequelae of intracranial injury
16.5
12.8
20
13
SPAT1262
SPAT
Handing over of treatment supplies
3.0
12.8
69
276
SPAT1211
SPAT
Application of soft bandage
3.9
12.8
41
118
N29
ICPC
Neurological sympt/complt other
18.4
12.7
19
11
R5140
NOMESCO Finland
Monitoring the use of the aid
3.3
12.6
55
194
P85
ICPC
Mental retardation
+∞
12.6
12
*
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
+∞
12.6
12
*
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
135.8
12.5
13
*
N39.4
ICD-10 Finland
Other specified urinary incontinence
4.2
12.5
36
96
G99.2*M47.9
ICD-10 Finland
Myelopathy in spondylosis
39.5
12.3
15
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
10.0
12.3
24
26
N03AX09
ATC
lamotrigine; oral
4.9
12.2
28
62
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
3.3
12.1
53
187
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.5
12.1
46
149
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
11.8
57
213
WX882
NOMESCO Finland
High dependency care
5.9
11.8
22
40
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.6
11.7
23
44
OAB50, ,
SPAT
3.7
11.7
40
120
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
67.9
11.7
13
*
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
8.9
11.6
24
29
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
+∞
11.5
11
*
W16
ICD-10 Finland
Diving or jumping into water causing injury other than drowning or submersion
+∞
11.5
11
*
A82
ICPC
Secondary effect of trauma
124.9
11.5
12
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
11.5
74
324
N06AA09
ATC
amitriptyline; systemic
3.7
11.5
40
122
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.1
11.4
33
88
K59.0
ICD-10 Finland
Constipation
4.1
11.4
33
88
WX725
NOMESCO Finland
Noninvasive ventilation
4.4
11.3
30
75
N02AA05
ATC
oxycodone; systemic
2.7
11.2
74
328
SPAT1216
SPAT
Assessment of functional ability
2.9
11.2
60
238
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.1
11.2
20
35
N02AX02
ATC
tramadol; systemic, rectal
2.4
11.1
143
861
JN4BD
NOMESCO Finland
Extensive body CT
3.3
11.1
46
157
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
4.6
11.0
27
63
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
45.2
11.0
13
*
SPAT1254
SPAT
Administration of medicine
3.0
10.8
55
212
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
62.4
10.7
12
*
G99.2
ICD-10 Finland
Myelopathy in diseases classified elsewhere
62.4
10.7
12
*
R5130, ,
SPAT
62.4
10.7
12
*
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
15.0
10.6
17
12
WX892
NOMESCO Finland
Monitored bed care
3.6
10.6
37
113
XKD00
NOMESCO Finland
Uroflowmetry
2.7
10.5
69
304
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.3
10.5
28
70
M41.4
ICD-10 Finland
Neuromuscular scoliosis
+∞
10.5
10
*
J01FF01
ATC
clindamycin; systemic
2.4
10.5
96
496
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
10.2
10.4
20
21
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.8
10.4
33
94
L29
ICPC
Musculoskeletal sympt/complt other
3.5
10.3
38
120
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
10.3
116
655
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
10.3
100
530
ZXE00
NOMESCO Finland
One hour or less
2.3
10.2
119
682
C03CA01
ATC
furosemide; systemic
2.4
10.1
102
548
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.4
10.1
26
63
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
10.1
58
238
XF400
NOMESCO Finland
ECG with 12 standard connections
2.7
10.0
64
278
NG4AA
NOMESCO Finland
Lower leg X-ray examination
5.4
10.0
20
39
M03BX02
ATC
tizanidine; oral
2.3
9.9
183
1260
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.4
9.9
38
123
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
9.9
56
228
NFL22
NOMESCO Finland
Myotomy or tenotomy of hip or thigh
57.0
9.7
11
*
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
10.6
9.7
18
18
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.3
9.7
40
136
WX730
NOMESCO Finland
Conventional respirator
15.8
9.6
15
10
R50.9
ICD-10 Finland
Fever, unspecified
2.6
9.6
65
290
Z50.1
ICD-10 Finland
Other physical therapy
4.0
9.6
28
75
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.0
9.6
46
171
R60.0
ICD-10 Finland
Localized oedema
2.9
9.5
50
195
R2110
NOMESCO Finland
Giving the first information
4.6
9.5
23
53
SPAT1255
SPAT
Intravenous administration of medicine
3.8
9.5
30
85
TJD20
NOMESCO Finland
Change of gastrostomy tube
31.2
9.5
12
*
V89
ICD-10 Finland
Motor- or nonmotor-vehicle accident, type of vehicle unspecified
103.4
9.5
10
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
103.4
9.5
10
*
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
22.6
9.4
13
6
S13.1
ICD-10 Finland
Dislocation of cervical vertebra
+∞
9.4
9
*
G82
ICD-10 Finland
Paraplegia and tetraplegia
+∞
9.4
9
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.5
9.4
35
111
B01AB05
ATC
enoxaparin; parenteral
2.3
9.3
101
558
R39.1
ICD-10 Finland
Other difficulties with micturition
5.1
9.2
20
42
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
9.2
38
129
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
10.6
9.2
17
17
G99.2*M50.0
ICD-10 Finland
Cervical disc disorder with myelopathy
16.3
9.1
14
9
R25.2
ICD-10 Finland
Cramp and spasm
7.9
9.1
20
27
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
38.0
9.1
11
*
S72.4
ICD-10 Finland
Fracture of lower end of femur
25.0
9.0
12
5
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.2
9.0
38
131
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
9.1
8.9
18
21
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
11.2
8.9
16
15
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
8.9
118
704
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.5
8.8
22
52
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.7
8.8
29
85
G04AA01, ,
ATC
51.6
8.7
10
*
NAG42
NOMESCO Finland
Posterior fusion of cervical spine with or without fixation
51.6
8.7
10
*
SPAT1231
SPAT
Assessment of adjustments needed in living environment
8.7
8.7
18
22
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
8.7
8.7
18
22
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
9.4
8.7
17
19
ZZR10
NOMESCO Finland
Flap of skin and muscle
17.0
8.6
13
8
ZXD10
NOMESCO Finland
Scheduled procedure
2.2
8.6
112
662
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.2
8.5
23
58
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.9
8.5
26
72
A08
ICPC
Swelling
3.6
8.5
29
87
Z93.5
ICD-10 Finland
Cystostomy status
92.7
8.5
9
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
7.5
8.4
19
27
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
11.2
8.4
15
14
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
8.2
47
192
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
12.2
8.2
14
12
R30.0
ICD-10 Finland
Dysuria
4.4
8.1
21
51
G61.0
ICD-10 Finland
Guillain-Barré syndrome
34.4
8.1
10
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.2
8.0
17
22
N03AF02
ATC
oxcarbazepine; oral
4.9
8.0
18
39
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.9
8.0
40
152
RF120, ,
NOMESCO Finland
13.6
8.0
13
10
R4120, ,
SPAT
13.6
8.0
13
10
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
4.3
8.0
21
52
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
8.9
7.9
16
19
WX002
NOMESCO Finland
Sedation and analgesia
2.4
7.9
65
316
Z2446
NOMESCO Finland
Social worker
3.3
7.9
31
102
TKC22
NOMESCO Finland
Catheterisation instruction
6.7
7.9
19
30
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.3
7.8
20
34
SPAT1301
SPAT
No procedures
2.1
7.8
96
551
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.2
7.8
21
53
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.8
7.8
24
67
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
7.7
31
103
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.1
7.7
33
114
N02BF01
ATC
gabapentin; oral
2.9
7.7
38
143
A29
ICPC
General symptom/complaint other
2.6
7.7
51
224
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.3
7.7
20
49
G04BD12
ATC
mirabegron; oral
2.7
7.6
44
180
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
10.5
7.6
14
14
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.8
7.6
42
168
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
8.0
7.5
16
21
RF310, ,
NOMESCO Finland
82.2
7.5
8
*
N21.0
ICD-10 Finland
Calculus in bladder
13.9
7.5
12
9
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
13.9
7.5
12
9
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
7.4
39
152
SPAT1125
SPAT
Stoma care and guidance
11.3
7.4
13
12
G04BE03
ATC
sildenafil; oral
9.8
7.4
14
15
ZXD35
NOMESCO Finland
Usual procedure
4.5
7.3
18
42
34302
ICD-8 Finland
Cerebral spastic infantile paralysis, Tetraplegia spastica
+∞
7.3
7
*
A123_, ,
NOMESCO Finland
+∞
7.3
7
*
80690
ICD-8 Finland
Fracture and fracture dislocation of vertebral column with spinal cord lesion, Cervicalis, Sequelae
+∞
7.3
7
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
7.2
55
258
Z02.7
ICD-10 Finland
Issue of medical certificate
3.2
7.2
29
97
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
12.5
7.1
12
10
J01XE01
ATC
nitrofurantoin; oral
10.4
7.1
13
13
R60.9
ICD-10 Finland
Oedema, unspecified
3.6
7.0
24
72
N05CD07
ATC
temazepam; oral
2.7
6.9
39
158
U28
ICPC
Limited function/disability (U)
11.3
6.9
12
11
R47.1
ICD-10 Finland
Dysarthria and anarthria
11.3
6.9
12
11
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
9.7
6.9
13
14
OAB43, ,
SPAT
0.3
6.8
18
540
R53
ICD-10 Finland
Malaise and fatigue
2.1
6.8
85
487
KH1AT
NOMESCO Finland
Urinary tract cathetrisation with ultrasound guidance
41.1
6.8
8
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
6.7
72
388
U08
ICPC
Urinary retention
6.7
6.7
16
25
M54.1
ICD-10 Finland
Radiculopathy
4.2
6.7
18
45
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
23.2
6.7
9
*
SPAT1234
SPAT
Support of social functional capacity
3.6
6.7
22
64
R4130
NOMESCO Finland
Speech therapy
4.0
6.7
19
50
KCE02
NOMESCO Finland
Transluminal endoscopic extraction of calculus from bladder
12.7
6.6
11
9
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
12.7
6.6
11
9
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
9.0
6.6
13
15
J01CF05
ATC
flucloxacillin; systemic
2.9
6.6
32
119
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
6.0
6.6
17
30
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.1
6.5
18
46
J01MA14
ATC
moxifloxacin; systemic
2.7
6.5
36
144
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
7.7
6.5
14
19
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.9
6.5
19
51
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
71.4
6.5
7
*
NDT99
NOMESCO Finland
Other operation on wrist or hand
71.4
6.5
7
*
S24.0
ICD-10 Finland
Concussion and oedema of thoracic spinal cord
71.4
6.5
7
*
G04BD07
ATC
tolterodine; oral
3.8
6.4
20
56
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.5
6.4
22
66
JN4AD
NOMESCO Finland
Body CT examination
2.5
6.4
44
196
OAA80, ,
SPAT
0.0
6.4
*
154
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
11.4
6.3
11
10
D17
ICPC
Incontinence of bowel
18.5
6.3
9
5
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.7
6.3
20
57
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.7
6.3
20
57
P21.0
ICD-10 Finland
Severe birth asphyxia
+∞
6.3
6
*
RT274, ,
NOMESCO Finland
+∞
6.3
6
*
AEA30
NOMESCO Finland
Replacement of implanted pump of injection device in the nervous system
+∞
6.3
6
*
3432A
ICD-9 Finland
Infantile cerebral palsy, Quadriplegic[CP-OIREYHTYMÄ,TETRAPLEGIA SPASTICA]
+∞
6.3
6
*
34403
ICD-8 Finland
Other cerebral paralysis, Laesia medullaris non traumatica, sequelae
+∞
6.3
6
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
+∞
6.3
6
*
Y85.0
ICD-10 Finland
Sequelae of motor-vehicle accident
+∞
6.3
6
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
4.1
6.3
17
43
SPAT1127
SPAT
Enema
27.3
6.3
8
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.0
6.2
16
28
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.4
6.2
47
219
OAA65, ,
SPAT
0.2
6.2
7
303
K90
ICPC
Stroke/cerebrovascular accident
5.4
6.1
17
33
S82.1
ICD-10 Finland
Fracture of upper end of tibia
10.4
6.1
11
11
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.0
6.1
17
44

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
173
645
5.40
43.37
8.4
3.1
—
—
—
0
0
161
720
3.91
28.16
8.5
4.4
—
—
—
0
0
82
303
3.41
17.91
3.2
1.7
—
—
—
0
0
28
44
6.96
17.45
5.2
3.2
—
—
—
0
0
71
246
3.53
17.09
3.2
2.7
0.18
0.22
g/l
2.05
66
226
31
56
6.10
16.90
3.5
2.8
44.79
3.64
e6/l
0.61
24
39
110
498
2.99
16.87
5.0
3.0
482.85
545.82
mosm/kgh2o
2.63
103
434
31
57
5.99
16.59
3.6
2.9
2312.17
2203.00
e6/l
0.01
24
42
119
573
2.87
16.16
4.6
2.7
5.02
5.32
e6/l
0.06
112
520
135
709
2.75
15.33
7.0
3.2
0.45
0.37
e6/l
0.20
117
515
60
204
3.47
14.72
7.8
5.4
7.41
7.42
ph
0.72
53
167
64
227
3.36
14.69
2.7
2.1
0.00
0.00
estimate
—
10
61
114
564
2.72
14.37
3.8
2.7
—
—
—
0
0
49
151
3.72
13.91
7.4
5.4
—
—
—
0
0
181
1150
2.62
13.29
14.2
12.8
1.21
1.23
inr
0.29
160
959
138
774
2.54
13.18
4.4
2.6
—
—
—
0
0
41
121
3.80
12.34
2.8
2.3
0.00
0.00
estimate
-0.00
13
50
142
827
2.45
12.25
7.7
3.4
26.85
132.39
e6/l
0.73
126
627
182
1195
2.49
11.90
11.4
8.4
1.21
1.21
mmol/l
0.32
161
1038
81
368
2.69
11.74
3.2
2.2
—
—
—
0
0
135
782
2.40
11.62
3.6
2.7
46.20
60.49
u/l
1.84
124
733
89
429
2.58
11.40
3.7
4.3
0.81
0.81
mmol/l
0.27
82
412
151
926
2.37
11.32
9.3
4.2
85.84
89.49
e6/l
0.04
125
662
168
1081
2.39
11.25
11.7
8.1
1.21
1.21
mmol/l
0.22
155
999
165
1067
2.33
10.73
6.1
5.1
32.53
35.80
g/l
6.80
155
1007
138
829
2.31
10.67
9.1
7.3
—
—
—
0
0
17
15
11.98
9.70
4.3
1.1
1.88
1.70
mmol/l
0.32
17
15
79
387
2.45
9.58
1.9
1.7
1080.31
1218.59
nmol/l
0.72
60
284
184
1288
2.25
9.34
7.3
3.9
29.38
0.00
estimate
0.49
56
268
50
198
2.86
9.27
3.8
4.2
7.37
7.34
ph
0.30
42
142
108
623
2.19
8.83
2.7
2.2
3.09
2.87
mg/l
0.36
89
545
185
1319
2.19
8.68
8.6
7.2
11.24
12.62
umol/l
0.63
176
1259
65
308
2.45
8.38
13.5
10.2
7.41
7.41
ph
0.00
38
176
168
1166
2.10
8.30
9.9
7.2
2.71
2.83
%
0.27
160
1097
168
1167
2.10
8.27
9.9
7.3
8.58
8.95
%
0.98
161
1100
153
1028
2.08
8.23
5.8
3.4
6.55
6.19
ph
3.18
79
578
168
1169
2.09
8.21
9.7
7.2
59.43
57.11
%
1.40
163
1112
179
1279
2.11
8.10
7.4
3.8
0.00
0.00
estimate
-0.00
51
268
160
1097
2.07
8.10
4.5
2.9
—
—
estimate
—
0
0
64
306
2.41
8.07
13.5
10.2
2.34
0.90
mmol/l
1.58
56
257
181
1304
2.10
7.94
7.4
3.9
0.00
0.02
estimate
0.50
55
246
77
403
2.26
7.87
7.2
3.2
2.90
1.59
e6/l
0.30
52
196
166
1162
2.05
7.84
10.3
7.3
0.54
0.68
%
2.56
157
1088
169
1195
2.04
7.71
9.4
7.2
25.85
27.49
%
0.89
163
1133
49
950
0.41
7.50
2.9
3.1
—
—
—
0
0
177
1286
2.02
7.32
9.4
7.2
1.87
1.97
e9/l
0.38
156
1143
175
1273
2.00
7.13
9.1
7.1
0.04
0.04
e9/l
0.12
151
1093
174
1269
1.98
6.97
8.9
7.1
0.61
0.59
e9/l
0.42
150
1089
178
1310
1.98
6.93
9.3
7.5
0.20
0.19
e9/l
0.35
160
1149
12
12
10.39
6.60
1.5
1.2
0.59
0.45
ratio
—
7
7
186
1404
1.97
6.55
11.3
11.2
4.42
4.17
e9/l
0.81
162
1232
57
283
2.27
6.51
5.7
5.4
7.38
7.39
ph
0.45
36
169
40
170
2.58
6.41
6.5
5.8
25.13
24.22
mmol/l
0.95
40
170
110
708
1.91
6.21
7.7
3.9
0.00
0.00
estimate
-0.00
51
249
43
198
2.38
5.81
17.1
12.0
26.31
24.90
mmol/l
1.36
43
198
223
1827
2.08
5.80
11.6
8.7
86.99
80.89
u/l
0.77
212
1734
59
311
2.14
5.79
1.7
2.6
128.10
126.24
ug/g
0.02
42
258
142
1037
1.75
5.02
3.7
2.5
85.42
75.21
nmol/l
2.86
125
935
48
247
2.14
4.98
15.4
10.6
—
—
—
0
0
14
30
4.86
4.75
3.6
4.1
—
—
—
0
0
203
2321
0.54
4.63
5.0
5.8
2.49
2.69
mmol/l
2.51
181
2141
47
250
2.06
4.46
4.4
3.0
64.23
68.73
e9/l
0.36
34
182
21
77
2.87
4.46
1.3
1.3
287.62
309.25
ug/g
0.15
13
45
83
536
1.78
4.39
2.0
2.2
1.63
1.44
mg/l
0.17
66
433
132
970
1.68
4.37
6.9
4.2
26.02
36.19
ng/l
1.32
119
710
34
160
2.28
4.37
8.6
6.8
—
—
—
0
0
110
773
1.70
4.29
3.5
3.8
1114.32
1285.60
ng/l
0.30
96
655
199
2275
0.57
4.21
4.7
5.0
1.36
1.42
mmol/l
1.24
176
2093
52
293
1.95
4.20
3.3
3.6
9.12
9.40
umol/l
0.02
38
268
30
136
2.35
4.20
1.2
1.4
—
22.72
—
0
12
0
98
0.00
3.94
0.0
1.1
—
1.52
—
0
98
48
270
1.94
3.89
16.4
10.3
117.67
122.75
g/l
1.10
48
263
25
108
2.44
3.89
2.4
2.3
—
—
—
0
0
8
11
7.45
3.88
3.6
2.1
—
—
—
0
0
25
109
2.42
3.81
1.9
1.9
1.51
5.40
iu/ml
—
7
28
0
95
0.00
3.75
0.0
1.1
—
0.78
—
0
11
54
322
1.84
3.66
4.6
3.0
1.80
1.78
%
0.05
49
292
11
25
4.54
3.66
1.4
1.2
1749.00
1724.93
e6/l
—
6
14
15
52
2.99
3.52
9.1
3.2
—
—
—
0
0
22
95
2.43
3.43
4.3
1.9
—
—
—
0
0
139
1088
1.55
3.25
19.8
13.3
0.00
0.00
e9/l
0.17
110
899
30
152
2.09
3.24
19.0
13.5
15.95
15.81
%
0.10
30
145
11
29
3.90
3.22
1.1
1.6
—
—
—
0
0
132
1024
1.55
3.20
2.7
2.0
81.47
95.23
pmol/l
3.29
83
535
139
1092
1.54
3.18
3.8
2.9
133.89
134.68
ug/l
0.02
120
1018
32
168
2.02
3.15
1.3
1.3
278.61
289.47
u/ml
0.02
27
156
30
156
2.03
3.03
1.6
2.2
—
—
—
0
0
17
69
2.56
3.02
4.9
6.1
71.11
63.42
%
0.63
17
69
10
26
3.95
3.01
1.5
1.4
—
—
—
0
0
205
2282
0.62
2.97
4.6
5.1
4.33
4.57
mmol/l
2.40
183
2105
9
23
4.01
2.80
1.0
1.3
—
—
—
0
0
20
92
2.26
2.74
2.3
2.7
—
—
—
0
0
94
698
1.52
2.69
2.0
1.7
23.36
20.75
nmol/l
0.81
82
590
33
187
1.87
2.63
8.6
3.4
—
—
—
0
0
81
585
1.54
2.62
6.6
3.7
—
0.00
—
0
6
19
88
2.24
2.57
1.3
1.2
—
—
—
0
0
31
174
1.88
2.54
4.9
3.1
—
—
—
0
0
37
220
1.79
2.54
4.8
5.2
0.27
0.50
%
0.73
11
79
195
2174
0.66
2.50
4.1
4.3
1.22
1.30
mmol/l
0.74
169
1995
8
21
3.89
2.48
1.0
1.3
—
—
—
0
0
6
12
5.08
2.41
1.3
2.0
117.50
109.33
ug/l
—
6
12
62
429
1.57
2.41
3.4
2.3
9.73
13.95
umol/l
4.51
57
404
63
444
1.54
2.26
2.6
2.8
2.45
2.45
mmol/l
0.05
57
402
13
277
0.44
2.24
1.4
1.6
—
—
—
0
0
27
152
1.86
2.21
4.9
4.5
0.55
0.63
%
0.82
27
152
16
74
2.23
2.19
3.5
4.5
454.00
170.13
mg/l
—
6
40
50
337
1.59
2.17
1.4
1.4
445.71
448.00
titre
—
7
75
35
215
1.72
2.16
5.8
5.5
0.00
0.14
%
—
9
70
12
49
2.51
2.13
1.4
1.3
—
—
—
0
0
37
232
1.69
2.13
5.8
5.7
0.00
0.23
%
1.17
11
73
7
20
3.56
2.07
3.4
2.1
—
—
—
0
0
27
157
1.80
2.01
4.9
4.5
1.40
1.27
%
0.16
27
157
16
77
2.14
2.01
7.8
3.4
7.42
7.41
ph
0.23
16
77
102
808
1.41
2.00
2.8
3.5
2.30
2.35
mmol/l
3.56
92
733
13
263
0.47
1.96
1.2
1.6
—
—
—
0
0
5
11
4.61
1.95
1.2
1.5
—
—
—
0
0
66
485
1.47
1.93
1.7
1.8
455.00
27924083.04
pmol/l
0.50
54
419
9
34
2.70
1.88
1.2
1.2
—
—
nmol/l
—
0
0
36
232
1.63
1.88
5.8
5.3
0.50
0.85
%
—
10
87
5
12
4.22
1.83
1.2
1.0
—
—
—
0
0
20
109
1.90
1.82
1.5
1.6
—
11.78
—
0
5
75
572
1.43
1.80
1.3
1.3
1.06
1.70
u/ml
0.53
21
149
28
171
1.71
1.78
4.9
4.9
132.04
129.37
g/l
0.24
28
166
63
466
1.45
1.78
4.0
3.7
61.99
318.67
ng/l
2.05
49
366
91
720
1.39
1.77
5.5
4.3
7.40
7.40
ph
0.97
71
523
69
521
1.43
1.75
1.6
1.5
2.26
2.57
g/l
0.61
43
310
119
986
1.36
1.74
8.3
3.6
0.06
0.00
estimate
0.49
36
224
7
24
2.96
1.73
1.6
1.2
—
—
—
0
0
43
297
1.53
1.69
1.7
1.5
—
—
—
0
0
82
645
1.38
1.64
2.9
3.0
321.64
352.12
umol/l
1.44
64
567
14
70
2.05
1.62
1.4
1.2
—
—
—
0
0
31
203
1.59
1.54
1.1
1.2
—
—
—
0
0
10
45
2.27
1.48
1.5
3.1
—
—
—
0
0
34
230
1.54
1.48
2.6
3.0
26.19
34.72
u/l
1.53
26
190
81
990
0.74
1.43
2.0
2.0
1.45
1.38
mmol/l
0.29
69
833
9
40
2.29
1.41
1.8
1.7
—
—
—
0
0
9
40
2.29
1.41
1.8
1.7
—
—
—
0
0
9
40
2.29
1.41
1.8
1.7
—
—
—
0
0
9
40
2.29
1.41
1.8
1.6
—
—
—
0
0
146
1643
0.77
1.39
4.0
4.2
—
0.00
—
0
5
183
1649
1.32
1.38
5.0
3.5
49.11
49.82
u/l
0.06
170
1563
9
42
2.18
1.35
5.7
2.9
—
—
—
0
0
5
18
2.81
1.29
1.4
1.1
—
—
—
0
0
5
18
2.81
1.29
4.2
2.3
0.40
0.89
index
—
5
18
6
25
2.43
1.25
1.2
1.2
—
—
—
0
0
14
78
1.84
1.23
1.7
2.7
31.99
29.68
mg/l
0.18
14
66
14
78
1.84
1.23
1.7
2.7
39.86
41.91
mg/l
0.08
14
65
20
126
1.63
1.18
5.3
3.7
1.02
1.02
ratio
0.92
20
120
204
2180
0.76
1.17
6.6
6.5
39.67
39.55
mmol/mol
0.06
185
2045
8
39
2.08
1.16
4.9
4.4
—
—
—
0
0
43
322
1.40
1.15
4.8
3.4
4.64
5.06
e9/l
0.20
34
275
14
228
0.59
1.09
1.4
1.6
—
—
—
0
0
7
32
2.22
1.09
7.0
9.5
11.93
11.39
%
—
7
32
10
52
1.96
1.07
11.4
3.3
8.54
8.43
kpa
—
10
52
10
52
1.96
1.07
11.4
3.3
5.14
5.11
kpa
—
10
52
7
34
2.09
1.03
1.7
1.4
34.51
36.88
ng/l
—
7
34
5
23
2.19
0.98
4.8
4.5
14.80
17.33
%
—
5
23
7
36
1.97
0.97
2.6
2.9
3.79
4.96
e9/l
—
7
36
41
314
1.36
0.97
1.4
1.3
—
—
—
0
0
68
565
1.27
0.91
7.9
3.7
1.02
1.02
kg/l
0.43
47
378
35
268
1.35
0.84
1.8
2.4
13.07
13.99
nmol/l
0.22
29
247
84
723
1.23
0.83
10.4
7.0
—
—
—
0
0
243
2331
1.32
0.82
44.1
16.7
30.55
25.00
mg/l
1.90
229
1931
6
32
1.89
0.82
1.5
1.1
—
—
—
0
0
10
58
1.75
0.80
1.2
1.5
—
—
—
0
0
83
718
1.22
0.78
7.7
3.3
0.00
0.00
estimate
0.50
42
211
0
27
0.00
0.78
0.0
2.6
—
46.63
—
0
27
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
6
34
1.78
0.77
1.2
1.3
—
—
—
0
0
48
391
1.27
0.76
1.4
1.3
119.23
5.62
u/ml
0.46
14
154
11
67
1.67
0.76
6.0
5.1
—
—
—
0
0
5
25
2.02
0.73
1.4
1.2
—
—
—
0
0
5
25
2.02
0.73
4.2
2.4
21.40
12.44
index
—
5
18
26
195
1.37
0.72
1.3
1.6
—
—
—
0
0
18
126
1.46
0.72
6.3
4.8
37.03
36.92
°c
1.96
18
126
38
303
1.29
0.71
1.6
1.3
—
—
—
0
0
5
26
1.94
0.71
1.2
1.5
—
—
—
0
0
18
127
1.45
0.70
1.3
1.2
—
—
—
0
0
24
180
1.36
0.67
2.5
1.8
1.16
1.18
g/l
0.03
24
165
5
28
1.80
0.66
1.0
2.5
—
—
—
0
0
11
71
1.57
0.63
1.0
1.2
—
—
—
0
0
18
130
1.41
0.63
1.1
1.2
195.36
165.03
u/ml
—
7
41
0
23
0.00
0.58
0.0
14.7
—
1578.43
—
0
23
0
23
0.00
0.58
0.0
2.7
—
44.67
—
0
9
6
35
1.73
0.58
2.5
3.7
—
—
—
0
0
51
595
0.83
0.58
2.8
3.1
0.69
0.81
ug/l
0.58
36
381
184
1741
1.17
0.57
4.2
3.9
15.72
14.85
pmol/l
3.63
165
1596
6
39
1.55
0.53
1.5
1.9
—
—
—
0
0
6
97
0.61
0.53
1.0
1.1
—
—
—
0
0
7
48
1.47
0.47
4.1
3.1
5.76
9.42
pmol/l
—
7
48
50
435
1.18
0.45
1.7
1.8
—
—
—
0
0
7
50
1.41
0.45
1.1
1.0
—
—
—
0
0
69
767
0.87
0.44
3.5
3.5
54.18
52.63
mg/l
0.03
51
515
10
140
0.70
0.44
1.1
1.1
—
—
—
0
0
24
195
1.25
0.42
2.9
2.2
6.39
6.04
ph
1.16
18
126
5
33
1.52
0.41
2.8
3.2
107.20
105.39
mmol/l
—
5
33
5
33
1.52
0.41
2.8
3.2
3.84
4.09
mmol/l
—
5
33
5
33
1.52
0.41
2.8
3.2
1.21
1.19
mmol/l
—
5
33
247
2521
0.83
0.41
53.9
25.1
7.39
6.86
e9/l
2.94
241
2472
247
2521
0.83
0.41
53.7
25.0
4.36
4.53
e12/l
6.02
241
2475
8
60
1.34
0.40
1.0
1.1
—
—
—
0
0
247
2520
0.83
0.40
54.0
25.1
250.74
246.88
e9/l
0.33
242
2478
14
107
1.32
0.38
1.2
1.3
—
—
—
0
0
240
2449
0.86
0.34
18.0
12.3
28.88
26.96
u/l
0.70
233
2381
6
45
1.34
0.34
2.8
1.7
—
—
—
0
0
7
55
1.28
0.30
30.3
13.5
12.43
11.40
mmol/l
—
7
48
7
55
1.28
0.30
30.3
13.5
103.29
105.21
mmol/l
—
7
48
41
365
1.14
0.30
1.5
1.6
—
—
—
0
0
9
73
1.24
0.25
24.7
11.8
1.18
1.34
mmol/l
—
9
63
73
781
0.91
0.25
4.4
4.2
13.06
8.27
mg/mmol
0.44
53
504
95
1003
0.92
0.24
6.0
5.4
1.62
2.39
ug/l
2.11
88
896
5
38
1.32
0.23
1.4
1.3
—
—
—
0
0
5
38
1.32
0.23
3.4
2.0
39.36
37.25
%
—
5
38
15
125
1.21
0.23
3.5
3.2
4.70
4.48
pmol/l
0.27
15
114
7
91
0.76
0.23
1.4
1.5
—
—
—
0
0
7
94
0.74
0.22
1.4
1.5
—
—
—
0
0
7
94
0.74
0.22
1.4
1.5
—
—
—
0
0
7
94
0.74
0.22
1.4
1.5
—
—
—
0
0
7
95
0.73
0.22
1.7
1.8
153.29
243.85
pmol/l
—
7
87
216
2203
0.91
0.22
4.9
5.0
5.94
6.00
mmol/l
0.23
187
2021
5
42
1.19
0.21
1.2
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
40.64
—
0
11
0
11
0.00
0.21
0.0
43.9
—
6.78
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
1.23
—
0
10
95
904
1.08
0.21
2.6
2.1
—
—
—
0
0
21
184
1.15
0.19
1.1
1.7
—
—
—
0
0
19
217
0.87
0.19
1.4
1.5
—
—
—
0
0
54
578
0.92
0.19
6.4
5.2
—
—
—
0
0
15
129
1.17
0.17
15.9
7.9
1.67
1.49
%
0.64
15
119
7
63
1.11
0.17
2.6
2.4
53.71
58.76
%
—
7
63
7
63
1.11
0.17
1.3
1.2
—
—
—
0
0
7
86
0.81
0.15
1.4
1.5
—
—
—
0
0
72
688
1.06
0.14
1.5
1.4
—
—
—
0
0
32
297
1.09
0.13
1.6
1.5
—
—
—
0
0
13
115
1.14
0.10
18.2
8.5
0.96
0.86
%
0.60
13
103
31
294
1.06
0.07
1.3
1.4
—
—
—
0
0
8
90
0.89
0.07
1.3
1.6
—
—
—
0
0
13
142
0.91
0.06
2.0
1.5
0.27
0.33
mg/l
—
6
66
210
2113
0.98
0.04
5.4
4.8
1.79
1.94
mu/l
1.30
192
1933
239
2381
1.03
0.02
30.7
14.4
—
—
—
0
0
42
429
0.98
0.02
1.5
1.3
21.02
34.41
iu/ml
—
9
130
11
117
0.94
0.02
1.5
1.8
45.36
40.16
nmol/l
0.24
11
112
83
823
1.01
0.01
3.4
3.4
6.47
8.08
mmol/l
2.29
69
685
13
131
0.99
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
6.2
—
6.90
—
0
5
0
5
0.00
0.00
0.0
1.0
—
10.20
—
0
5
0
5
0.00
0.00
0.0
1.4
—
83.20
—
0
5
0
6
0.00
-0.00
0.0
9.2
—
4.58
—
0
6
7
75
0.93
-0.00
11.4
10.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.3
1.03
0.88
nmol/l
—
5
50
0
9
0.00
-0.00
0.0
3.4
—
37.78
—
0
9
0
9
0.00
-0.00
0.0
6.9
—
9.89
—
0
9
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
40.00
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.8
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
9126.50
—
0
6
7
72
0.97
-0.00
1.4
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
8
82
0.97
-0.00
1.5
1.6
231.38
308.95
mu/l
—
8
75
0
6
0.00
-0.00
0.0
2.7
—
2.33
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint G6_TETRAPLE and mortality.

Females

Parameter HR [95% CI] p-value
G6_TETRAPLE 4.524 [3.57, 5.73] < 0.001
Birth year 0.996 [0.99, 1.0] 0.319

During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 1131 females with G6_TETRAPLE died.

Males

Parameter HR [95% CI] p-value
G6_TETRAPLE 4.224 [3.6, 4.96] < 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 782 out of 1973 males with G6_TETRAPLE died.

Mortality risk

Mortality risk for people of age

years, who have G6_TETRAPLE.

N-year risk Females Males
1 0.438% 0.861%
5 2.374% 5.06%
10 6.461% 12.798%
15 11.992% 21.439%
20 20.747% 34.276%

Relationships between endpoints

↥

Index endpoint: G6_TETRAPLE – Tetraplegia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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