No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
941 |
4. Check minimum number of eventsNone |
941 |
5. Include endpointsNone |
941 |
6. Filter based on genotype QC (FinnGen only) |
849 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Ventricular septal defect, a heart condition
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of cardiac septa
- Congenital malformations of heart and great arteries
- Congenital malformations of the circulatory system
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 849 | 525 | 324 |
| Unadjusted period prevalence (%) | 0.17 | 0.19 | 0.15 |
| Median age at first event (years) | 11.67 | 12.58 | 10.20 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 891
- Matched controls
- 8883
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
307.7
342
*
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
307.7
532
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
307.7
375
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
25.3
206.6
151
71
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
8.7
205.1
342
593
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
12.9
203.6
222
223
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
16.7
194.2
175
128
201
Kela drug reimbursment
Chronic cardiac insufficiency
17.3
194.0
171
120
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.9
181.6
435
1079
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
159.1
148
*
31
HP
Congenital heart failure surgery
65.0
129.8
72
12
Q21.19
ICD-10 Finland
Atrial septal defect NOS
50.1
104.6
61
13
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
13.1
101.9
102
87
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
39.0
100.0
62
17
XF400
NOMESCO Finland
ECG with 12 standard connections
4.8
97.9
293
823
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
513.8
95.1
93
*
B01AA03
ATC
warfarin; systemic
6.4
93.8
179
338
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.6
93.0
169
304
Q25.1
ICD-10 Finland
Coarctation of aorta
25.3
92.7
66
28
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
17.3
92.3
78
49
XF404
NOMESCO Finland
Ambulatory ECG
6.8
91.7
162
283
C01AA05
ATC
digoxin; systemic
10.7
85.2
97
100
FM2CE, ,
NOMESCO Finland
7.2
82.5
133
210
Q25.0
ICD-10 Finland
Patent ductus arteriosus
15.3
78.9
71
50
61
HP
Catheterization and pressure measurement of the left side of the heart
24.2
78.8
57
25
C03CA01
ATC
furosemide; systemic
4.4
75.1
238
685
C03DA01
ATC
spironolactone; oral
5.8
75.0
154
309
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.5
73.3
160
339
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
9.0
71.5
93
114
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
13.9
69.5
66
51
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
18.0
68.1
56
33
XF402
NOMESCO Finland
ECG with work load test
6.2
68.0
127
232
XF620
NOMESCO Finland
Examination of circulation with color method
89.4
67.0
74
9
TPH07
NOMESCO Finland
Cathetrisation of artery
4.6
65.0
181
468
XF640, ,
NOMESCO Finland
13.7
60.0
57
44
XFE00
NOMESCO Finland
Epicardial ultrasonography
13.1
59.3
58
47
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
57.2
456
2290
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.7
56.6
221
725
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
18.7
53.5
43
24
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
17.7
53.2
44
26
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
275.2
51.6
52
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.7
49.8
185
583
XF600
NOMESCO Finland
Bloodpressure measurement
4.0
49.0
157
446
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
48.3
46
*
Q23.11
ICD-10 Finland
Bicuspid aortic valve
12.4
44.7
45
38
I50.9
ICD-10 Finland
Heart failure, unspecified
4.9
44.7
106
238
TFP20
NOMESCO Finland
Cardiodefibrillation
6.5
44.3
75
123
Z2221
NOMESCO Finland
Medical doctor
2.8
43.3
326
1538
ZXD10
NOMESCO Finland
Scheduled procedure
2.6
43.3
401
2098
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
230.4
43.3
44
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
43.2
328
1554
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
64.5
42.6
49
8
I48
ICD-10 Finland
Atrial fibrillation and flutter
4.0
42.3
134
376
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
6.8
41.3
67
105
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
40.7
352
1769
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
9.8
39.0
46
49
62
HP
Catheterization and pressure measurement of the right side of the heart
65.8
38.4
44
7
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
7.7
38.4
55
75
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
37.7
36
*
C01BD01
ATC
amiodarone; systemic
10.9
36.7
40
38
5207
FHL
VSD closure
+∞
36.7
35
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.5
35.8
94
228
Z98.8
ICD-10 Finland
Other specified postsurgical states
9.7
34.6
41
44
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
6.5
33.7
57
93
G04BE03
ATC
sildenafil; oral
12.2
32.6
33
28
WX872
NOMESCO Finland
Intensive care
6.3
31.8
55
92
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.2
30.3
137
481
XF622
NOMESCO Finland
Measurement of minute volume of heart
29.5
27.7
37
13
WX882
NOMESCO Finland
High dependency care
3.5
27.5
105
331
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
9.5
27.4
33
36
Q20.1
ICD-10 Finland
Double outlet right ventricle
77.4
26.9
30
*
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
9.2
26.9
33
37
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
24.9
25.8
36
15
WX892
NOMESCO Finland
Monitored bed care
3.3
25.7
105
345
C07AB07
ATC
bisoprolol; oral
2.2
25.0
285
1556
I35.0
ICD-10 Finland
Aortic (valve) stenosis
5.6
24.4
47
87
K84
ICPC
Heart disease other
8.4
24.4
32
39
Z3231
NOMESCO Finland
Registered nurse
2.1
23.3
325
1909
207
Kela drug reimbursment
Chronic arrhythmias
3.4
22.5
86
271
RS224, ,
NOMESCO Finland
6.6
22.2
36
56
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
7.2
22.1
33
47
ZXE00
NOMESCO Finland
One hour or less
2.0
21.8
381
2415
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
19.4
21.4
32
17
Q21.30
ICD-10 Finland
Tetralogy of Fallot
19.4
21.4
32
17
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
21.3
21.3
31
15
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
19.8
234
1279
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.9
19.7
60
162
I37.0
ICD-10 Finland
Pulmonary valve stenosis
107.1
19.6
21
*
C07AA07
ATC
sotalol; systemic
6.8
19.6
31
47
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
17.1
19.2
30
18
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
6.8
19.2
30
45
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
15.2
19.0
31
21
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
+∞
18.8
18
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
71.2
18.7
21
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
101.9
18.6
20
*
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
22.2
18.2
26
12
I34.1
ICD-10 Finland
Mitral (valve) prolapse
6.2
18.1
31
51
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
17.7
17
*
90492, ,
NOMESCO Finland
96.7
17.6
19
*
I44.2
ICD-10 Finland
Atrioventricular block, complete
6.5
17.6
29
46
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.6
17.0
109
457
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
16.7
211
1173
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
15.4
16.7
27
18
Q20.48
ICD-10 Finland
Single ventricle
28.1
16.5
22
8
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
28.1
16.5
22
8
WX402
NOMESCO Finland
General anaesthesia
1.9
16.5
253
1506
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
40.8
16.4
20
5
Q26.1
ICD-10 Finland
Persistent left superior vena cava
40.8
16.4
20
5
R4110
NOMESCO Finland
Physiotherapy
1.9
16.3
264
1599
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
48.3
16.0
19
*
I50.0
ICD-10 Finland
Congestive heart failure
4.1
16.0
44
110
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
12.5
15.9
28
23
FHB00
NOMESCO Finland
Transatrial suture of VSD
+∞
15.6
15
*
Q21.80
ICD-10 Finland
Communication from left ventricle to right atrium
162.3
15.5
16
*
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
162.3
15.5
16
*
ZXD05
NOMESCO Finland
Urgent procedure
1.9
15.5
253
1532
C07AB02
ATC
metoprolol; systemic
2.4
15.5
116
522
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.1
15.3
42
105
ZX199
NOMESCO Finland
Other rote
6.8
15.3
24
36
UGC02
NOMESCO Finland
Rigid bronchoscopy
7.1
15.3
23
33
WX704
NOMESCO Finland
Intubation
2.7
15.0
83
322
5253
FHL
Cardiac lung machine
32.2
14.8
19
6
I50.1
ICD-10 Finland
Left ventricular failure
5.0
14.8
32
66
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.9
14.6
44
118
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
30.5
13.9
18
6
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.1
13.6
58
195
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
13.6
13
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
34.5
13.5
17
5
Q21.21
ICD-10 Finland
Atrioventricular duct
34.5
13.5
17
5
Q22.0
ICD-10 Finland
Pulmonary valve atresia
34.5
13.5
17
5
Q21.1
ICD-10 Finland
Atrial septal defect
141.7
13.5
14
*
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.3
13.4
27
52
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
13.4
181
1023
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
21.5
13.3
19
9
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
15.3
13.1
21
14
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.8
12.8
67
253
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
17.6
12.5
19
11
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
12.5
12
*
Q21.8
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
12.5
12
*
FHB96
NOMESCO Finland
Other closure of congenital ventricular septal defect
+∞
12.5
12
*
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
+∞
12.5
12
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
131.4
12.4
13
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.7
12.1
69
272
Q25.40
ICD-10 Finland
Aortic hypoplasia
18.3
12.1
18
10
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
27.0
12.1
16
6
ZX120
NOMESCO Finland
Intravenous
2.3
12.0
91
411
C09AA05
ATC
ramipril; oral
2.1
11.9
116
580
C09AA02
ATC
enalapril; systemic
2.3
11.9
97
451
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
47.2
11.9
14
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
9.8
11.8
23
24
Z3226
NOMESCO Finland
Physiotherapist
1.8
11.6
193
1163
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
23.2
11.6
16
7
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
11.6
149
826
I42.0
ICD-10 Finland
Dilated cardiomyopathy
5.8
11.5
21
37
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
11.5
11
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
11.5
193
1167
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
121.2
11.4
12
*
7AX01, ,
NOMESCO Finland
12.0
11.3
20
17
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
35.4
11.3
14
*
I49.5
ICD-10 Finland
Sick sinus syndrome
5.0
11.2
24
49
Q90.9
ICD-10 Finland
Down syndrome, unspecified
25.3
11.1
15
6
ZX108
NOMESCO Finland
Inhalation
5.3
11.1
22
42
I47.2
ICD-10 Finland
Ventricular tachycardia
5.0
10.7
23
47
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
21.7
10.7
15
7
Q20.00
ICD-10 Finland
Common arterial trunk
60.6
10.6
12
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.3
10.6
21
40
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
10.5
157
914
AF1
HP
Surgery of congenital heart defect
110.9
10.4
11
*
51
HP
Other heart surgery
+∞
10.4
10
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.3
10.3
38
117
I48.4
ICD-10 Finland
Atypical atrial flutter
23.6
10.2
14
6
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.9
10.2
49
177
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
10.0
161
957
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
40.4
10.0
12
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
26.3
9.8
13
5
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
20.2
9.8
14
7
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.1
9.7
102
525
Z50.1
ICD-10 Finland
Other physical therapy
3.2
9.7
39
127
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.9
9.7
46
165
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
55.4
9.6
11
*
Q21.3
ICD-10 Finland
Tetralogy of Fallot
55.4
9.6
11
*
B01AB05
ATC
enoxaparin; parenteral
1.8
9.6
169
1030
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
10.1
9.5
18
18
Z2446
NOMESCO Finland
Social worker
1.9
9.5
121
667
C02KX01
ATC
bosentan; oral
100.8
9.4
10
*
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
100.8
9.4
10
*
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
100.8
9.4
10
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
100.8
9.4
10
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
9.4
170
1045
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
+∞
9.4
9
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
9.4
9
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
+∞
9.4
9
*
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
21.9
9.4
13
6
I48.1
ICD-10 Finland
Persistent atrial fibrillation
4.6
9.3
22
49
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
13.8
9.2
15
11
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
9.1
274
1927
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.0
187
1193
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
9.0
93
475
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
37.0
9.0
11
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.1
9.0
24
59
K83
ICPC
Heart valve disease NOS
18.8
8.9
13
7
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
18.8
8.9
13
7
J01CA04
ATC
amoxicillin; systemic
2.0
8.9
801
7258
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
4.5
8.8
21
47
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
4.7
8.8
20
43
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.6
8.7
51
204
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
14.2
8.7
14
10
Q22.5
ICD-10 Finland
Ebstein anomaly
50.3
8.7
10
*
FM1BD
NOMESCO Finland
Extensive CT of heart
16.4
8.6
13
8
FM1AD
NOMESCO Finland
CT of heart
27.7
8.5
11
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
90.6
8.4
9
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
90.6
8.4
9
*
AP3
HP
Catheterization of the right and left side of the heart
90.6
8.4
9
*
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.6
8.4
49
196
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
12.9
8.4
14
11
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
6.8
8.4
20
30
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
6.8
8.4
20
30
5609
FHL
Other measure in this category
+∞
8.3
8
*
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
+∞
8.3
8
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.9
8.2
39
140
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
14.6
8.2
13
9
AP2
HP
Catheterization of the right side of the heart
33.6
8.1
10
*
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
33.6
8.1
10
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
6.9
8.1
19
28
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.4
8.0
57
250
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.3
8.0
58
257
602
Kela drug reimbursment
Children's severe malnutrition
2.8
7.9
39
143
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
4.7
7.9
18
39
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
10.9
7.8
14
13
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.6
7.7
44
174
1EA01, ,
NOMESCO Finland
15.1
7.7
12
8
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
15.1
7.7
12
8
APK
HP
ASD closure
45.2
7.7
9
*
AA1AD
NOMESCO Finland
CT of head and brain
1.7
7.6
154
973
R62.0
ICD-10 Finland
Delayed milestone
2.4
7.6
51
218
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
25.2
7.6
10
*
WZC30
NOMESCO Finland
Teaching
1.8
7.6
114
662
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
6.2
7.5
19
31
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
80.5
7.4
8
*
Q22.41
ICD-10 Finland
Tricuspid atresia
80.5
7.4
8
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
80.5
7.4
8
*
FDB20
NOMESCO Finland
Arterial switch operation for other congenital heart defect
80.5
7.4
8
*
Q76.48
ICD-10 Finland
Congenital anomalies of other vertebrae, not associated with scoliosis
80.5
7.4
8
*
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
80.5
7.4
8
*
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
80.5
7.4
8
*
TK800
NOMESCO Finland
Hemodialysis
4.1
7.3
20
50
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
+∞
7.3
7
*
4168X
ICD-9 Finland
Chronic pulmonary heart disease, Other chronic pulmonary heart diseases
+∞
7.3
7
*
5501
FHL
Pulmonary artery stenosis
+∞
7.3
7
*
Q21.88
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
7.3
7
*
Q25.3
ICD-10 Finland
Stenosis of aorta
15.8
7.2
11
7
Z31.5
ICD-10 Finland
Genetic counselling
2.0
7.2
80
420
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
30.2
7.1
9
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
20.1
7.1
10
5
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
20.1
7.1
10
5
I44.1
ICD-10 Finland
Atrioventricular block, second degree
7.0
7.0
16
23
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
7.0
172
1143
205
Kela drug reimbursment
Chronic hypertension
1.8
6.8
96
547
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
5.7
6.8
18
32
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
6.8
82
444
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
40.2
6.8
8
*
I27.0
ICD-10 Finland
Primary pulmonary hypertension
40.2
6.8
8
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
40.2
6.8
8
*
Q87.14
ICD-10 Finland
Noonan's syndrome
16.8
6.7
10
6
K78
ICPC
Atrial fibrillation/flutter
2.8
6.7
33
121
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
22.6
6.7
9
*
AN1
HP
Coronary angiography
2.5
6.7
42
175
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.0
6.6
29
100
F83
ICD-10 Finland
Mixed specific developmental disorders
2.5
6.5
41
171
GD1LA
NOMESCO Finland
GD
6.2
6.5
16
26
Q17.2
ICD-10 Finland
Microtia
70.1
6.4
7
*
4302
FHL
Tooth patching under general anesthesia
70.1
6.4
7
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
70.1
6.4
7
*
7454X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[VSD ALIA DEFINITA]
70.1
6.4
7
*
5205
FHL
ASD blockage, secondary defect
70.1
6.4
7
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.4
6.4
22
65
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.6
6.3
15
23
XG460
NOMESCO Finland
Short time oxymetry
5.2
6.3
18
35
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.2
6.3
24
76
7456C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[ASD CANALIS ATRIOVENTRICULARIS COMMUNIS]
+∞
6.2
6
*
FGE10
NOMESCO Finland
Replacement of tricuspid valve using biological prosthesis
+∞
6.2
6
*
FM2FN
NOMESCO Finland
Intra cardiac shunt isotope imaging
+∞
6.2
6
*
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
+∞
6.2
6
*
7454E
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[VSD MULTIPLEX]
+∞
6.2
6
*
Q24.0
ICD-10 Finland
Dextrocardia
26.8
6.2
8
*
1201, ,
NOMESCO Finland
26.8
6.2
8
*
RS220, ,
NOMESCO Finland
3.1
6.2
25
82
81
HP
Angiography of the heart and coronary arteries
3.1
6.2
25
82
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.8
6.2
98
578
250, ,
Kela drug reimbursment
5.4
6.2
17
32
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
6.2
552
6223
R04.0
ICD-10 Finland
Epistaxis
2.1
6.1
53
254
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
423
1270
5.42
136.15
7.4
4.3
1159.39
965.51
ng/l
0.47
393
1051
190
346
6.69
103.76
5.0
4.5
183.79
189.98
ng/l
0.06
176
309
37
30
12.79
37.60
4.7
6.8
4.94
4.89
kpa
0.12
37
30
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
79
164
5.17
36.32
18.2
15.9
0.32
0.37
iu/ml
0.85
50
91
417
2365
2.42
36.15
28.6
8.6
1.48
1.14
inr
19.31
347
1949
237
1078
2.62
32.50
5.7
3.5
1263.70
695.00
ng/l
1.78
197
666
103
330
3.39
26.29
34.5
13.9
16.12
15.80
%
0.56
103
320
226
1130
2.33
24.41
10.5
9.0
0.82
0.82
mmol/l
0.40
219
1084
137
545
2.78
23.94
28.5
12.1
95.46
95.46
%
0.00
137
534
144
601
2.66
22.86
27.3
11.5
0.22
0.31
mmol/l
0.11
130
500
145
609
2.64
22.72
27.0
11.3
13.76
13.86
kpa
0.07
145
589
145
609
2.64
22.72
27.0
11.3
5.26
5.21
kpa
0.22
145
587
124
493
2.75
21.60
25.0
11.3
121.60
121.32
g/l
0.05
124
485
32
21
15.71
19.82
2.3
2.0
100.09
96.57
g/l
0.59
32
21
198
1024
2.19
19.24
3.6
2.9
21.50
22.76
%
0.79
190
976
300
1813
1.98
19.14
3.2
2.9
—
—
—
0
0
176
872
2.26
18.97
18.1
10.7
105.61
104.92
mmol/l
1.21
176
872
315
1944
1.95
18.85
9.9
6.9
74.53
89.44
%
17.23
309
1915
89
330
2.88
17.58
2.4
2.5
19.99
6.59
ug/l
3.74
77
288
205
1113
2.09
17.40
3.6
2.8
2.45
2.45
g/l
0.04
196
1039
214
1199
2.03
16.58
3.7
2.9
13.02
13.96
umol/l
1.31
205
1134
93
381
2.60
15.13
7.5
11.1
0.65
0.60
%
0.81
93
381
282
1825
1.79
13.67
4.0
3.1
48.28
37.92
ng/l
0.38
180
1001
55
184
3.11
13.01
1.5
1.4
—
—
—
0
0
435
3208
1.69
13.00
3.8
3.2
—
—
estimate
—
0
0
184
1084
1.87
11.91
12.9
10.0
1.89
0.77
mmol/l
6.55
154
793
439
3324
1.62
11.27
10.3
7.3
19.06
16.52
umol/l
0.89
410
3131
93
436
2.26
11.21
9.2
11.4
129.56
128.81
g/l
0.10
93
428
432
3296
1.60
10.48
21.3
11.3
1.21
1.22
mmol/l
4.46
413
3097
461
3576
1.59
10.39
16.5
10.9
1.21
1.22
mmol/l
2.48
413
3220
199
1253
1.75
10.20
9.2
10.1
5.92
5.77
kpa
1.48
194
1228
196
1237
1.74
9.94
9.4
10.1
1.21
1.07
mmol/l
0.24
174
1021
369
2764
1.56
9.36
8.4
6.7
36.56
37.31
g/l
1.48
350
2627
186
1178
1.73
9.25
9.0
10.1
5.03
4.93
kpa
0.24
181
1155
519
4202
1.55
9.24
14.3
6.9
6.15
6.25
mmol/l
0.67
493
3910
792
7158
1.93
8.77
27.4
15.0
139.40
139.54
mmol/l
1.05
783
6993
57
242
2.44
8.62
1.6
2.5
1.20
1.29
g/l
0.27
41
217
791
7159
1.90
8.53
27.5
15.1
3.97
3.94
mmol/l
2.44
781
6972
223
1525
1.61
8.16
4.4
3.3
1.47
1.40
mg/l
0.09
171
1143
36
125
2.95
8.05
1.5
1.4
—
—
—
0
0
120
700
1.82
7.85
4.2
6.4
308.64
280.25
u/l
0.48
115
677
21
54
3.95
7.43
1.8
1.8
164.19
123.17
%
1.32
21
54
282
2085
1.51
7.16
3.1
2.8
3.01
2.57
mg/l
1.19
252
1842
133
834
1.69
6.75
2.4
2.0
—
—
—
0
0
161
1067
1.62
6.58
2.4
2.0
—
—
—
0
0
33
123
2.74
6.53
3.0
3.3
16.50
17.11
%
0.59
33
118
17
42
4.09
6.34
2.1
1.3
994.42
3622.52
e6/l
1.01
12
25
127
809
1.66
6.06
2.5
2.0
—
—
—
0
0
314
2445
1.43
5.89
5.1
4.1
34.88
32.11
u/l
0.38
306
2335
574
4973
1.42
5.82
9.1
7.2
94.32
95.50
u/l
0.15
554
4709
498
4235
1.39
5.47
3.9
3.5
79.52
75.07
ug/l
0.32
476
4024
85
503
1.76
5.30
2.8
2.7
—
—
—
0
0
23
80
2.92
5.19
4.3
4.2
0.78
0.80
index
0.04
23
80
224
1684
1.44
4.95
3.1
2.3
383.18
267.40
u/l
0.59
214
1614
38
174
2.23
4.93
2.3
2.8
131.72
132.38
g/l
0.06
32
146
70
408
1.77
4.62
2.5
3.1
65.55
66.14
g/l
0.19
65
384
44
220
2.05
4.60
4.3
3.3
7.65
5.00
index
0.23
31
137
54
295
1.88
4.40
2.5
1.9
—
—
—
0
0
94
604
1.62
4.34
6.2
7.5
73.14
60.97
ng/l
0.84
86
570
35
164
2.17
4.33
1.8
1.4
—
—
—
0
0
15
38
3.98
4.30
2.0
1.3
58893.90
45830.00
e6/l
—
10
19
301
2448
1.34
4.02
5.0
4.1
27.22
61.10
e6/l
0.60
235
1792
54
306
1.81
3.94
2.9
2.0
—
—
—
0
0
22
89
2.50
3.80
2.2
2.0
—
—
—
0
0
39
203
1.96
3.70
2.1
2.0
—
—
—
0
0
47
261
1.84
3.68
10.4
7.7
23.69
24.37
mmol/l
0.43
47
250
42
226
1.89
3.62
2.1
1.5
—
—
—
0
0
269
2186
1.32
3.53
4.7
4.0
0.66
0.31
e6/l
0.74
204
1544
29
138
2.13
3.50
1.5
1.8
9.64
10.28
g/l
0.47
24
129
52
304
1.75
3.45
9.3
7.3
47.02
51.43
%
0.65
52
298
65
405
1.65
3.43
4.9
4.6
1.22
1.23
mmol/l
0.39
60
346
203
1592
1.35
3.38
4.3
3.1
6.62
7.30
e6/l
0.26
186
1420
29
141
2.09
3.32
1.2
1.2
1.25
4.15
u/ml
1.27
12
60
15
54
2.80
3.24
1.5
1.3
—
—
—
0
0
26
124
2.12
3.14
1.3
1.8
0.00
0.00
g/l
-0.00
20
114
740
6941
1.37
3.12
27.2
17.6
13.54
13.28
%
5.38
734
6874
36
195
1.88
3.08
2.2
1.9
—
—
—
0
0
26
127
2.07
2.97
1.3
1.8
0.00
0.04
g/l
0.50
21
121
81
551
1.51
2.97
6.0
4.9
—
—
—
0
0
28
141
2.01
2.95
1.0
1.1
—
—
—
0
0
260
2150
1.29
2.93
3.3
3.0
2.37
2.37
mmol/l
0.55
245
1971
54
829
0.63
2.84
1.0
1.1
—
—
—
0
0
30
158
1.92
2.81
1.5
1.8
3.51
3.58
g/l
0.13
25
150
30
158
1.92
2.81
1.5
1.8
4.09
4.25
g/l
0.34
25
150
30
158
1.92
2.81
1.5
1.8
6.75
7.39
g/l
1.42
25
150
25
124
2.04
2.76
2.3
1.3
—
—
—
0
0
29
152
1.93
2.75
1.5
1.8
3.23
3.00
g/l
0.64
24
144
527
4763
1.25
2.74
11.8
11.3
3.96
3.75
e9/l
1.33
457
4013
796
7591
1.43
2.74
20.6
13.2
25.39
22.10
mg/l
2.09
674
5886
32
174
1.86
2.73
1.8
1.9
—
—
—
0
0
23
111
2.09
2.73
2.0
1.6
—
—
—
0
0
6
10
6.01
2.69
16.5
16.3
11.18
11.28
%
—
6
10
41
242
1.72
2.69
13.0
9.8
845.00
312.23
iu/ml
—
6
30
27
140
1.95
2.65
1.2
1.3
5.68
4.34
u/ml
0.25
19
68
27
141
1.94
2.60
1.3
2.0
0.47
0.70
g/l
0.25
22
131
45
276
1.66
2.58
8.0
6.2
24.71
24.32
mmol/l
0.35
45
267
125
949
1.36
2.55
7.6
5.6
10.47
7.04
umol/l
1.00
110
799
50
316
1.61
2.55
2.6
2.1
114.00
111.92
au/ml
0.04
20
126
626
5797
1.26
2.51
17.1
10.8
94.01
95.12
ml/min/173m2
0.48
551
4966
37
217
1.73
2.49
3.2
2.2
2.90
4.46
iu/l
0.86
12
95
9
26
3.48
2.47
1.8
2.3
213.22
195.58
u/l
—
9
26
9
26
3.48
2.47
1.6
1.2
206.56
738.36
u/l
—
9
26
6
176
0.34
2.42
1.7
1.9
—
—
—
0
0
22
113
1.96
2.25
2.6
1.6
14365.81
16621.48
e6/l
0.10
16
84
29
164
1.79
2.23
1.9
1.5
—
—
—
0
0
518
4732
1.22
2.21
5.3
4.2
635.55
1117.28
e6/l
0.21
11
58
23
121
1.92
2.20
2.1
1.9
—
—
—
0
0
29
165
1.78
2.19
2.6
2.3
—
—
—
0
0
21
109
1.94
2.10
2.4
1.4
—
—
—
0
0
229
1935
1.24
2.09
3.5
2.8
59.40
61.27
u/l
0.18
210
1821
247
2850
0.81
2.07
1.6
1.7
1.37
2.83
u/ml
1.35
65
636
12
50
2.41
2.02
3.4
2.7
4.10
4.03
mmol/l
0.22
12
50
9
32
2.82
1.99
1.3
1.8
—
—
—
0
0
9
32
2.82
1.99
1.3
1.8
—
—
—
0
0
9
32
2.82
1.99
1.3
1.8
—
—
—
0
0
9
32
2.82
1.99
1.3
1.8
—
—
—
0
0
236
2012
1.23
1.97
4.4
3.6
0.00
0.00
estimate
0.50
81
729
23
390
0.58
1.87
2.1
1.6
0.29
0.26
mg/l
—
7
162
21
115
1.84
1.82
7.8
5.7
8.06
7.67
pmol/l
0.10
21
115
16
299
0.52
1.82
1.0
1.1
0.81
0.86
g/l
0.40
16
299
66
479
1.40
1.81
1.7
1.6
—
—
—
0
0
61
439
1.41
1.76
2.2
1.8
—
—
—
0
0
48
330
1.48
1.76
1.6
1.4
—
—
—
0
0
28
170
1.66
1.73
2.6
2.0
1.09
2.99
ug/l
0.58
28
150
163
1354
1.25
1.73
4.9
3.7
335.39
317.22
umol/l
1.24
152
1227
22
125
1.77
1.71
4.8
5.0
1.45
1.40
mmol/l
0.11
22
120
16
292
0.54
1.70
1.0
1.1
1.46
1.52
g/l
0.46
16
292
28
171
1.65
1.70
3.6
4.1
—
—
—
0
0
231
2638
0.83
1.69
1.7
1.7
1.85
1.85
g/l
0.02
156
1501
19
104
1.84
1.67
1.0
1.0
166.74
162.99
g/l
0.37
19
104
32
204
1.58
1.65
8.1
7.6
1.42
1.55
%
0.52
32
191
11
49
2.25
1.63
3.6
2.7
1.20
1.20
mmol/l
0.05
11
49
11
49
2.25
1.63
3.6
2.7
104.09
105.88
mmol/l
0.53
11
49
163
1366
1.23
1.60
4.0
3.8
2.03
2.60
e6/l
0.57
83
681
7
26
2.70
1.57
1.9
1.7
—
—
—
0
0
28
176
1.61
1.54
4.1
3.9
353.75
180.63
e6/l
1.31
20
119
8
33
2.43
1.53
1.0
1.6
—
—
—
0
0
6
144
0.41
1.52
1.5
1.5
—
—
—
0
0
859
8410
1.51
1.50
30.9
20.1
88.85
88.44
fl
1.61
853
8338
33
218
1.53
1.49
1.5
3.1
—
—
—
0
0
32
210
1.54
1.48
1.4
1.6
—
—
—
0
0
52
377
1.40
1.47
3.0
4.2
9.77
19.47
ug/l
0.34
38
286
859
8413
1.50
1.46
31.0
20.1
4.55
4.57
e12/l
0.59
840
8162
859
8413
1.50
1.46
35.7
21.0
39.83
40.55
%
0.97
853
8335
47
336
1.42
1.45
1.6
1.7
—
—
—
0
0
46
630
0.71
1.44
4.0
3.7
33.12
32.08
%
0.28
33
441
34
228
1.51
1.44
1.7
1.4
—
—
—
0
0
34
228
1.51
1.44
1.7
1.4
—
—
—
0
0
24
148
1.63
1.44
2.1
1.7
—
—
—
0
0
167
1419
1.21
1.44
3.8
3.6
0.64
0.84
e6/l
0.74
89
732
16
88
1.83
1.41
1.5
1.6
—
—
—
0
0
859
8417
1.49
1.41
32.3
20.4
133.56
134.62
g/l
1.15
854
8342
858
8408
1.47
1.37
31.1
20.2
247.64
263.84
e9/l
10.86
841
8179
6
23
2.61
1.36
1.3
2.0
—
—
—
0
0
6
23
2.61
1.36
1.3
2.0
—
—
—
0
0
6
23
2.61
1.36
1.3
2.0
—
—
—
0
0
53
392
1.37
1.35
1.9
1.8
—
—
—
0
0
19
112
1.71
1.35
1.4
1.2
—
—
—
0
0
99
801
1.26
1.34
1.3
1.5
144.27
390.37
u/ml
1.49
91
749
21
331
0.62
1.34
1.0
1.1
0.05
1.13
u/ml
1.41
11
159
0
39
0.00
1.34
0.0
1.1
—
—
—
0
0
0
39
0.00
1.34
0.0
1.1
—
—
—
0
0
0
39
0.00
1.34
0.0
1.2
—
—
—
0
0
0
39
0.00
1.34
0.0
1.1
—
—
—
0
0
0
39
0.00
1.34
0.0
1.1
—
—
—
0
0
0
40
0.00
1.32
0.0
1.2
—
—
—
0
0
0
40
0.00
1.32
0.0
1.4
—
—
—
0
0
30
202
1.50
1.27
1.8
2.1
—
—
—
0
0
23
347
0.65
1.22
1.0
1.1
3.09
10.30
u/ml
4.85
18
212
25
367
0.67
1.18
1.1
1.1
6.05
7.38
u/ml
0.20
20
234
12
64
1.88
1.17
1.2
1.7
—
—
—
0
0
12
64
1.88
1.17
1.2
1.7
—
—
—
0
0
12
64
1.88
1.17
1.2
1.7
—
—
—
0
0
128
1494
0.83
1.17
2.9
3.1
96.65
102.75
ug/g
0.12
107
1201
26
378
0.68
1.17
1.3
1.4
—
—
—
0
0
43
317
1.37
1.15
1.4
1.5
55.00
57.64
ug/l
0.18
43
317
89
726
1.25
1.15
2.0
2.4
3564.23
7297.23
u/l
1.08
26
265
88
1064
0.81
1.14
2.0
1.7
1.50
1.41
%
0.74
81
960
65
813
0.78
1.13
1.2
1.2
—
48.20
—
0
7
55
426
1.31
1.08
3.7
3.0
56.94
74.82
ml/min/173m2
1.75
16
171
13
74
1.76
1.06
1.4
1.1
—
—
—
0
0
120
1020
1.20
1.05
1.6
1.6
494.48
36920030.06
pmol/l
1.28
102
883
634
6555
0.88
1.01
3.9
3.8
—
—
—
0
0
99
1166
0.83
1.01
1.3
1.3
2.44
10.09
u/ml
2.90
41
418
52
404
1.30
1.01
1.9
1.9
263.84
189.80
u/ml
0.95
32
196
271
2947
0.88
0.99
2.0
2.0
—
—
—
0
0
9
49
1.84
0.98
1.7
2.2
—
17.71
—
0
23
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
25
173
1.45
0.97
3.8
3.9
415.61
552.79
e6/l
1.31
18
113
0
31
0.00
0.96
0.0
1.7
—
—
—
0
0
118
1015
1.18
0.93
2.0
2.3
2.42
2.43
mmol/l
0.38
105
885
13
78
1.67
0.91
16.5
12.4
105.92
105.36
mmol/l
0.24
13
70
47
368
1.29
0.88
1.5
1.7
—
—
—
0
0
15
228
0.65
0.88
1.7
1.3
—
—
—
0
0
16
103
1.56
0.87
2.0
3.3
1.13
1.56
ratio
—
7
50
26
187
1.40
0.84
1.8
1.9
—
—
—
0
0
11
65
1.70
0.82
7.0
5.6
—
—
—
0
0
61
734
0.82
0.80
2.8
2.4
33.21
29.55
u/l
0.46
53
597
8
48
1.67
0.78
1.1
1.1
—
—
—
0
0
174
1918
0.88
0.78
2.2
2.4
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
—
—
0
0
13
82
1.59
0.77
1.5
1.3
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
56
675
0.82
0.76
1.7
1.5
3.32
3.32
mmol/l
0.01
46
451
162
1453
1.14
0.75
4.6
4.3
12.46
20.46
mg/mmol
0.26
112
967
5
24
2.08
0.74
2.0
1.2
—
—
—
0
0
186
2034
0.89
0.74
2.3
2.6
—
—
—
0
0
140
1249
1.14
0.71
1.6
1.5
—
—
—
0
0
52
426
1.23
0.71
1.4
1.3
165.33
244.48
miu/ml
0.86
18
206
31
397
0.77
0.71
1.5
1.5
1.24
1.15
ratio
0.25
20
253
31
397
0.77
0.71
1.5
1.5
1.31
1.21
ratio
0.23
20
253
31
397
0.77
0.71
1.5
1.5
1.01
0.94
ratio
0.67
20
253
20
273
0.72
0.70
1.8
3.6
340.00
433.23
mg/l
1.22
20
266
11
69
1.60
0.68
2.5
2.5
32.00
32.45
pg
0.16
11
69
409
3879
1.09
0.67
4.5
3.6
0.00
0.00
estimate
-0.00
91
764
415
3940
1.09
0.67
4.6
3.7
0.01
0.00
estimate
0.49
81
731
74
856
0.85
0.66
1.7
1.6
3.31
3.40
ratio
0.28
59
620
7
44
1.59
0.65
1.1
1.2
—
—
—
0
0
28
215
1.31
0.64
1.6
1.6
—
—
—
0
0
411
3905
1.09
0.64
4.6
3.7
14.80
0.00
estimate
0.49
91
759
8
49
1.63
0.62
1.0
1.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
616
5970
1.09
0.59
5.0
4.1
14.72
14.51
pmol/l
1.34
565
5477
31
386
0.79
0.59
1.5
1.5
—
—
—
0
0
11
72
1.53
0.58
2.8
4.0
5421.32
456.06
u/ml
0.42
11
65
22
285
0.76
0.57
1.6
1.6
27.06
7.23
u/ml
—
7
63
6
36
1.67
0.56
1.0
1.1
21.63
32.44
u/ml
—
6
36
39
320
1.22
0.55
2.5
2.5
24.44
31.41
u/ml
0.58
39
306
43
511
0.83
0.54
1.5
1.4
—
—
—
0
0
242
2568
0.92
0.54
1.9
2.0
1.29
1.32
mmol/l
0.21
215
2267
12
82
1.47
0.54
1.3
1.5
6.53
7.16
mmol/l
0.53
12
71
9
61
1.48
0.53
2.7
3.4
970.56
1099.31
u/ml
—
9
61
80
704
1.15
0.52
1.3
1.3
144.22
142.18
u/ml
0.02
35
259
41
486
0.83
0.51
1.1
1.2
2.99
3.05
u/ml
0.01
32
332
84
744
1.14
0.51
1.7
1.6
1105.38
1165.98
nmol/l
0.29
61
562
14
189
0.73
0.49
1.1
1.2
94.60
202.12
iu/ml
—
5
53
42
353
1.20
0.49
1.5
1.4
—
—
—
0
0
7
47
1.49
0.47
2.0
1.6
—
—
—
0
0
20
254
0.78
0.47
1.8
3.6
3.58
3.48
mmol/l
0.25
20
241
7
48
1.46
0.46
2.1
2.1
—
—
—
0
0
7
48
1.46
0.46
3.0
5.4
—
—
—
0
0
12
164
0.73
0.46
1.0
1.1
5.55
14.83
u/ml
—
6
42
7
49
1.43
0.46
1.9
1.2
172.37
209.56
pmol/l
—
7
49
7
51
1.37
0.44
1.0
1.1
987.71
1428.04
miu/ml
—
7
51
51
443
1.16
0.42
1.3
1.3
—
—
—
0
0
5
32
1.56
0.42
1.2
1.7
—
—
—
0
0
6
95
0.63
0.42
2.2
2.4
1.57
2.31
mmol/l
—
6
72
210
2216
0.93
0.41
4.4
4.0
7.17
8.29
mmol/l
2.57
190
1982
37
314
1.18
0.40
1.1
1.1
23.53
23.09
au/ml
—
8
54
5
34
1.47
0.40
1.4
1.1
—
—
—
0
0
14
182
0.76
0.40
1.4
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
6
41
1.46
0.36
1.2
1.2
—
—
—
0
0
6
41
1.46
0.36
2.7
4.5
82.20
157.07
ug/l
—
6
41
5
77
0.65
0.36
1.8
1.7
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
79
0.63
0.35
1.0
1.3
—
—
—
0
0
5
79
0.63
0.35
1.6
1.3
—
—
—
0
0
765
7536
1.09
0.35
13.8
10.7
25.43
26.01
u/l
0.41
748
7334
5
80
0.62
0.35
1.0
1.3
—
—
—
0
0
5
80
0.62
0.35
1.6
1.3
—
—
—
0
0
5
80
0.62
0.35
1.6
1.3
—
—
—
0
0
19
153
1.24
0.35
3.9
5.2
398.74
406.45
umol/l
0.09
19
145
28
236
1.19
0.34
1.9
1.9
25.28
21.35
ng/l
0.36
28
236
33
283
1.17
0.33
6.6
4.8
31.43
22.97
nmol/l
2.01
33
276
54
483
1.12
0.32
1.3
1.2
—
27.39
—
0
23
27
229
1.18
0.31
1.1
1.2
—
—
—
0
0
7
54
1.29
0.30
1.0
1.5
—
—
—
0
0
49
543
0.89
0.29
1.2
1.2
4.81
3.00
u/ml
0.30
36
364
7
56
1.25
0.29
1.1
1.7
—
—
—
0
0
8
106
0.75
0.29
3.6
5.9
4.10
2.20
ug/l
—
8
106
8
108
0.74
0.29
2.5
2.1
—
—
—
0
0
7
57
1.23
0.29
13.7
15.1
889.43
830.07
nmol/l
—
7
57
20
235
0.85
0.26
1.3
1.2
—
—
—
0
0
13
104
1.25
0.26
1.2
1.3
—
—
—
0
0
12
95
1.26
0.26
2.4
2.0
146.67
134.00
ng/l
0.21
12
88
5
75
0.66
0.26
1.0
1.3
—
—
—
0
0
119
1254
0.94
0.25
1.3
1.3
18.89
25.74
iu/ml
0.49
29
320
6
82
0.73
0.24
1.5
1.3
—
—
—
0
0
6
83
0.72
0.24
1.5
1.3
—
—
—
0
0
6
83
0.72
0.24
1.5
1.3
—
—
—
0
0
45
493
0.91
0.23
1.1
1.2
1.75
1.24
u/ml
0.28
31
315
5
38
1.31
0.23
2.4
1.8
0.97
1.39
mg/l
—
5
25
5
38
1.31
0.23
2.4
1.8
2.48
2.50
mg/l
—
5
30
5
38
1.31
0.23
2.4
1.8
0.11
1.71
mg/l
—
5
27
5
38
1.31
0.23
2.4
1.8
1.59
5.20
mg/l
—
5
28
5
38
1.31
0.23
2.4
1.8
1.61
2.40
mg/l
—
5
29
5
38
1.31
0.23
2.4
1.8
1.11
1.19
mg/l
—
5
30
5
38
1.31
0.23
2.4
1.8
1.10
2.91
mg/l
—
5
31
5
38
1.31
0.23
2.4
1.8
0.35
1.15
mg/l
—
5
28
168
1605
1.05
0.23
1.6
1.5
18.37
19.89
nmol/l
0.91
148
1383
5
39
1.28
0.23
5.8
10.1
—
—
—
0
0
22
251
0.87
0.21
1.0
1.1
—
2.07
—
0
24
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
1.21
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
46
500
0.91
0.21
1.1
1.2
6.75
6.18
u/ml
0.09
34
357
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
11
89
1.24
0.20
1.2
1.2
0.51
0.51
nmol/l
0.02
11
83
77
721
1.07
0.20
3.8
4.0
24.95
21.94
%
0.77
33
300
6
48
1.25
0.20
1.3
1.2
—
—
—
0
0
6
49
1.22
0.20
1.2
1.1
—
45.60
—
0
5
56
599
0.93
0.19
1.2
1.3
—
—
—
0
0
23
258
0.89
0.18
2.0
3.8
298.39
307.22
e6/l
0.01
18
180
58
540
1.08
0.18
2.4
2.1
8.52
7.39
u/l
0.28
39
353
588
5931
0.97
0.18
4.3
3.7
5.60
5.63
mmol/l
0.26
550
5493
7
60
1.16
0.17
1.1
1.1
—
83.75
—
0
8
7
60
1.16
0.17
1.1
1.6
—
1313.38
—
0
12
571
5623
1.03
0.17
4.0
3.6
1.18
1.20
mmol/l
0.26
539
5293
16
138
1.16
0.17
4.9
3.8
20.46
23.60
mg/l
0.19
16
96
23
256
0.89
0.17
2.0
3.8
5.28
8.33
e6/l
0.25
18
171
8
70
1.14
0.16
3.1
1.4
—
—
—
0
0
8
72
1.11
0.16
1.3
1.0
—
—
—
0
0
9
78
1.15
0.15
1.2
1.2
—
—
—
0
0
9
79
1.14
0.15
1.2
1.2
—
—
—
0
0
522
5267
0.97
0.15
4.8
4.4
9.12
8.95
mm/h
0.13
491
4938
7
86
0.81
0.14
1.1
1.2
—
—
—
0
0
205
2094
0.97
0.13
4.2
2.9
0.00
0.00
estimate
0.80
73
629
20
221
0.90
0.13
1.3
1.3
3.58
12.41
u/ml
—
5
35
52
548
0.94
0.13
2.7
2.9
0.61
0.75
ug/l
1.00
28
311
255
2492
1.03
0.13
2.0
1.9
92.56
97.28
pmol/l
0.84
155
1289
13
113
1.15
0.12
8.0
7.7
24.77
510.47
mg/mmol
0.60
13
103
23
250
0.92
0.11
1.3
1.9
—
—
—
0
0
37
391
0.94
0.10
1.5
1.8
—
—
—
0
0
43
452
0.95
0.10
1.7
1.7
—
—
—
0
0
5
44
1.13
0.10
5.4
4.3
152.80
84.13
u/ml
—
5
44
286
2810
1.02
0.09
4.3
3.2
0.00
0.00
estimate
0.80
74
639
613
6071
1.02
0.09
4.4
4.1
4.42
4.56
mmol/l
3.19
586
5768
120
1166
1.03
0.09
2.1
2.2
—
—
—
0
0
341
3359
1.02
0.09
3.5
3.2
74.01
71.10
nmol/l
1.07
308
3121
5
62
0.80
0.08
1.2
1.3
—
—
—
0
0
95
922
1.03
0.08
4.5
4.6
1.34
2.29
ug/l
1.65
85
830
83
804
1.03
0.08
1.5
1.6
1088.05
969.03
mu/l
0.60
72
716
8
74
1.08
0.07
1.0
1.2
118.50
114.88
pmol/l
—
8
74
557
5587
0.98
0.07
5.2
4.9
36.94
37.27
mmol/mol
0.40
526
5311
478
4732
1.02
0.07
4.7
3.8
46.56
35.68
u/l
2.31
457
4539
9
86
1.04
0.07
1.3
1.3
83.89
80.66
%
—
9
86
34
323
1.05
0.07
1.6
1.7
6.80
3.46
mg/l
0.58
19
228
608
6093
0.98
0.07
4.8
4.4
2.64
2.72
mmol/l
1.64
579
5769
13
142
0.91
0.07
1.6
1.8
—
2880.00
—
0
5
9
100
0.90
0.06
1.0
1.0
—
—
—
0
0
60
615
0.97
0.05
2.4
1.9
12.26
15.54
iu/l
0.68
44
433
23
217
1.06
0.05
1.3
1.2
—
—
—
0
0
180
1817
0.98
0.05
3.9
3.2
1.02
1.02
kg/l
0.49
109
1157
25
238
1.05
0.04
1.1
1.2
—
—
—
0
0
23
239
0.96
0.03
1.9
1.4
269.76
358.13
ug/g
1.40
17
133
35
339
1.03
0.03
1.3
1.8
2.35
4.90
iu/ml
—
10
66
23
221
1.04
0.02
1.5
1.5
2.94
4.37
ug/l
1.48
23
202
27
277
0.97
0.02
1.3
1.4
—
—
—
0
0
10
106
0.94
0.01
1.5
1.2
—
—
—
0
0
22
226
0.97
0.01
1.0
1.0
-1.07
-3.13
mmol/l
—
9
57
683
6802
1.00
0.00
6.0
4.9
1.98
1.88
mu/l
1.29
639
6410
26
257
1.01
0.00
2.2
1.7
43.65
38.84
nmol/l
0.35
26
248
134
1338
1.00
0.00
2.3
2.4
—
—
—
0
0
15
147
1.02
0.00
4.6
4.0
1.56
1.62
umol/l
0.14
15
142
603
6016
1.00
0.00
4.3
4.0
1.41
1.45
mmol/l
1.43
574
5688
24
234
1.02
0.00
1.1
1.2
—
—
—
0
0
8
89
0.90
0.00
1.1
4.8
—
—
—
0
0
8
89
0.90
0.00
1.1
4.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7532.00
—
0
5
9
91
0.99
-0.00
1.4
1.2
—
—
—
0
0
9
94
0.95
-0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.1
—
—
—
0
0
7
75
0.93
-0.00
1.4
1.5
0.50
0.49
e9/l
—
7
75
9
97
0.92
-0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
0.71
—
0
7
0
5
0.00
-0.00
0.0
10.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
2.8
2.2
—
1175.83
—
0
6
9
98
0.91
-0.00
1.0
1.1
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.2
508.00
226.62
iu/ml
—
5
49
0
8
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
16.09
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
95
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
97.40
—
0
5
9
90
1.00
-0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
93
0.96
-0.00
1.4
1.2
—
—
—
0
0
5
49
1.02
-0.00
4.0
7.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
221.33
—
0
6
6
68
0.88
-0.00
1.2
1.1
12.00
34.54
iu/ml
—
6
68
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_VENTRICULAR_SEPTAL_DEFECT – Ventricular septal defect, a heart condition
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).