Anorexia

R18_ANOREXIA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 R63.0
  • Hospital discharge: ICD-9 7830|3071
  • Hospital discharge: ICD-8 78400
  • Cause of death: ICD-10 R63.0
  • Cause of death: ICD-9 7830|3071
  • Cause of death: ICD-8 78400

2 out of 7 registries used, show all original rules.

635

4. Check minimum number of events

None

635

5. Include endpoints

None

635

6. Filter based on genotype QC (FinnGen only)

578

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6577 4584 1950
Only index persons 5178 3786 1392
Unadjusted period prevalence (%)
Whole population 0.11 0.13 0.05
Only index persons 0.12 0.14 0.05
Median age at first event (years)
Whole population 21.18 18.99 25.35
Only index persons 19.50 18.42 22.42

-FinnGen-

Key figures

All Female Male
Number of individuals 578 451 127
Unadjusted period prevalence (%) 0.14 0.16 0.06
Median age at first event (years) 30.02 20.41 64.15

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
601
Matched controls
6010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R63.0
ICD-10 Finland
Anorexia
1834.2
307.7
333
*
F50.0
ICD-10 Finland
Anorexia nervosa
82.7
192.5
103
15
3071A
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Anorexia nervosa
+∞
151.7
139
*
78400
ICD-8 Finland
Symptoms referable to upper gastro-intestinal tract, Anorexia
+∞
105.4
98
*
F50.9
ICD-10 Finland
Eating disorder, unspecified
25.0
98.3
71
32
F50.1
ICD-10 Finland
Atypical anorexia nervosa
43.5
97.7
59
15
R63.4
ICD-10 Finland
Abnormal weight loss
8.4
53.3
74
99
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
5.8
51.7
105
210
E87.6
ICD-10 Finland
Hypokalaemia
7.8
41.9
61
86
7830A
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Anorexia
+∞
40.0
38
*
N05AH03
ATC
olanzapine; systemic
4.8
36.1
90
213
N05AA02
ATC
levomepromazine; systemic
6.6
35.6
60
99
N06AB03
ATC
fluoxetine; oral
3.7
35.4
137
448
N05AH04
ATC
quetiapine; oral
3.2
34.4
185
741
N91.1
ICD-10 Finland
Secondary amenorrhoea
8.7
32.9
43
53
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.4
32.1
144
515
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.6
31.1
122
400
R53
ICD-10 Finland
Malaise and fatigue
2.7
30.0
241
1185
N05AX08
ATC
risperidone; systemic
3.9
29.3
98
288
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.1
29.2
65
139
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
9.1
28.7
36
42
E86
ICD-10 Finland
Volume depletion
9.2
28.3
35
40
N03AX09
ATC
lamotrigine; oral
4.6
28.2
73
177
P86
ICPC
Anorexia nervosa/bulimia
65.2
27.2
31
5
R11
ICD-10 Finland
Nausea and vomiting
3.4
25.6
105
352
N06AX11
ATC
mirtazapine; oral
2.5
24.8
263
1448
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
24.4
206
1020
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.8
23.3
79
233
F50.2
ICD-10 Finland
Bulimia nervosa
21.1
23.3
34
17
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
22.5
238
1296
N05BA04
ATC
oxazepam; oral
2.4
22.3
214
1116
N05BA01
ATC
diazepam; systemic, rectal
3.0
21.9
110
414
K59.09
ICD-10 Finland
Constipation, unspecified
3.8
21.0
68
194
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.5
20.7
53
127
N06AX16
ATC
venlafaxine; oral
2.7
20.5
132
567
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.1
20.0
58
153
N05CD07
ATC
temazepam; oral
3.1
20.0
92
329
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.9
19.9
62
172
N05AX12
ATC
aripiprazole; systemic
4.2
19.8
55
140
N03AG01
ATC
valproic acid; systemic, rectal
3.6
19.6
68
203
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
19.3
85
296
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.0
18.5
41
87
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.0
18.3
89
328
N06AB05
ATC
paroxetine; oral
3.7
18.1
60
174
F50.8
ICD-10 Finland
Other eating disorders
23.6
17.9
25
11
N03AE01
ATC
clonazepam; systemic
3.9
17.7
55
152
N06AB04
ATC
citalopram; systemic
2.4
17.4
157
785
N06AX03
ATC
mianserin; oral
4.1
17.2
49
127
N03AX16
ATC
[U] pregabalin
2.3
17.2
161
817
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.1
17.0
48
124
P99
ICPC
Psychological disorders other
4.6
16.9
41
94
N05AF03
ATC
chlorprothixene; systemic
5.2
16.1
34
69
N05AB03
ATC
perphenazine; systemic, rectal
4.7
16.1
38
85
G03FB06
ATC
medroxyprogesterone and estrogen; systemic
3.3
16.0
64
209
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
16.0
170
907
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.3
15.7
62
201
30650
ICD-8 Finland
Special symptoms not elsewhere classified, Feeding disturbance
+∞
15.7
15
*
N05BA06
ATC
lorazepam; systemic, sublingual
3.7
15.6
52
151
K59.0
ICD-10 Finland
Constipation
3.6
15.4
53
157
N05AH02
ATC
clozapine; systemic
5.7
15.4
29
53
P29
ICPC
Psychological sympt/compl other
2.8
15.3
83
324
N06AB10
ATC
escitalopram; oral
2.2
15.2
168
908
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
4.0
14.9
44
117
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
6.3
14.8
25
41
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.3
14.7
30
59
N05CF01
ATC
zopiclone; oral
2.0
14.6
211
1259
A04
ICPC
Weakness/tiredness general
2.3
14.3
127
625
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
4.8
13.9
32
70
N05AN01
ATC
lithium; oral
4.5
13.8
34
79
P15
ICPC
Chronic alcohol abuse
5.4
13.5
27
52
A03FA02
ATC
cisapride; oral, rectal
3.2
13.4
57
193
AA400
NOMESCO Finland
Electroconvulsive therapy
14.2
13.3
22
16
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.4
13.3
49
152
N06AX12
ATC
bupropion; oral
2.8
12.6
66
252
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.3
12.5
49
158
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.0
12.2
57
204
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
12.1
257
1720
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
6.0
11.9
21
36
N04AA02
ATC
biperiden; systemic
5.3
11.8
24
47
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
11.8
96
453
SPAT1240
SPAT
Therapeutic discussion
2.4
11.8
90
413
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.6
11.7
39
113
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
5.7
11.7
22
40
N06AB06
ATC
sertraline; oral
2.3
11.6
103
505
T08
ICPC
Weight loss
5.2
11.6
24
48
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
11.5
102
500
N06AX26
ATC
vortioxetine; oral
2.6
11.3
67
272
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.5
11.3
39
116
A03FA01
ATC
metoclopramide; systemic, rectal
2.0
10.9
157
921
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.1
10.9
30
76
A28
ICPC
Limited function/disability NOS
2.2
10.9
108
553
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
3.3
10.8
42
135
A06AD11
ATC
lactulose; oral
2.3
10.7
92
444
SPAT1301
SPAT
No procedures
1.9
10.7
195
1235
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
10.7
97
479
Z29
ICPC
Social problem NOS
4.4
10.7
27
64
P76
ICPC
Depressive disorder
2.6
10.6
65
269
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
5.6
10.5
20
37
SPAT1307
SPAT
Psychosocial counselling and guidance
2.7
10.3
59
236
R33
ICD-10 Finland
Retention of urine
3.0
10.2
45
156
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
10.1
89
434
Z2446
NOMESCO Finland
Social worker
2.7
10.0
57
227
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
3.7
9.9
32
91
M05BA04
ATC
alendronic acid; oral
2.6
9.6
59
244
N06AX21
ATC
duloxetine; oral
2.2
9.6
90
449
3075B
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Other and unspecified disorders of eating[AHMIMISHÄIRIÖ]
+∞
9.4
9
*
P01
ICPC
Feeling anxious/nervous/tense
2.0
9.4
117
650
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.0
9.4
42
147
IHZ05, ,
SPAT
2.9
9.3
45
164
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.6
9.3
31
90
F32.8
ICD-10 Finland
Other depressive episodes
4.9
9.1
20
42
F50.3
ICD-10 Finland
Atypical bulimia nervosa
10.3
9.1
17
17
UJF32
NOMESCO Finland
Coloscopy
1.9
9.0
140
837
F34.1
ICD-10 Finland
Dysthymia
3.2
9.0
36
118
N05BA12
ATC
alprazolam; oral
2.4
9.0
67
304
G03DB01
ATC
dydrogesterone; oral
2.0
8.8
102
551
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.6
8.8
51
205
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
8.8
161
1013
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
8.7
58
249
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.0
8.7
38
131
F61.0
ICD-10 Finland
Mixed personality disorders
4.7
8.6
20
44
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.9
8.6
25
66
N06AA04
ATC
clomipramine; systemic
6.6
8.5
21
33
ZY010
NOMESCO Finland
Hospital outpatient
2.7
8.5
48
190
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.9
8.5
40
144
F20.9
ICD-10 Finland
Schizophrenia, unspecified
4.4
8.5
21
49
E44.0
ICD-10 Finland
Moderate protein-energy malnutrition
91.3
8.4
9
*
2768A
ICD-9 Finland
Disorders of fluid, electrolyte and acid-base balance, Hypopotassaemia[HYPOKALAEMIA]
91.3
8.4
9
*
N05AD01
ATC
haloperidol; systemic
3.8
8.4
25
67
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
8.0
8.4
18
23
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.8
8.4
19
41
K59.1
ICD-10 Finland
Functional diarrhoea
2.7
8.4
44
168
7830C, ,
ICD-9 Finland
+∞
8.3
8
*
UKC02
NOMESCO Finland
Cystoscopy
2.1
8.2
78
391
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
8.1
250
1809
62600
ICD-8 Finland
Disorders of menstruation, Absent
22.4
8.0
11
5
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
7.9
34
116
SPAT1167
SPAT
Insertion of urinary catheter
4.7
7.9
18
39
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
7.9
7.9
17
22
F60.9
ICD-10 Finland
Personality disorder, unspecified
6.2
7.9
20
33
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.6
7.9
46
186
N06AG02
ATC
moclobemide; oral
3.1
7.9
32
106
AA1AD
NOMESCO Finland
CT of head and brain
1.8
7.8
153
978
Z72.8
ICD-10 Finland
Other problems related to lifestyle
15.3
7.7
12
8
R50.9
ICD-10 Finland
Fever, unspecified
1.9
7.7
101
569
SPAT1254
SPAT
Administration of medicine
2.0
7.7
93
510
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.8
7.6
39
147
N03AF02
ATC
oxcarbazepine; oral
3.3
7.6
29
92
F60.0
ICD-10 Finland
Paranoid personality disorder
18.6
7.6
11
6
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
7.5
182
1230
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
7.4
225
1614
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
9.5
7.3
14
15
R13
ICD-10 Finland
Dysphagia
2.4
7.3
49
212
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
4.4
7.3
18
42
F21
ICD-10 Finland
Schizotypal disorder
16.0
7.2
11
7
2961D
ICD-9 Finland
Affective psychoses, Manic disorder, recurrent episode[VAKAVA MASENNUSTILA,VAIKEA-ASTEINEN]
16.0
7.2
11
7
P03
ICPC
Feeling depressed
2.0
7.2
81
433
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
7.1
112
668
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.9
7.1
33
118
UJD02
NOMESCO Finland
Gastroscopy
2.9
7.1
33
118
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
12.2
7.1
12
10
IGY99
NOMESCO Finland
Other psychiatric treatment contact
3.2
7.1
28
91
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.6
7.1
42
171
SPAT1260
SPAT
Consultation of another employee
1.9
7.0
105
616
C07AA05
ATC
propranolol; systemic
1.7
7.0
136
864
RD210, ,
NOMESCO Finland
4.1
6.9
19
48
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
6.9
182
1253
A27
ICPC
Fear of other disease NOS
2.7
6.9
37
143
JN4AD
NOMESCO Finland
Body CT examination
2.2
6.9
61
297
R55
ICD-10 Finland
Syncope and collapse
2.1
6.9
66
332
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
6.9
85
469
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
8.4
6.9
14
17
F33.8
ICD-10 Finland
Other recurrent depressive disorders
8.4
6.9
14
17
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.5
6.8
41
169
F42.9
ICD-10 Finland
Obsessive-compulsive disorder, unspecified
7.3
6.7
15
21
L28
ICPC
Limited function/disability (L)
1.8
6.7
108
649
IHZ04, ,
SPAT
3.8
6.7
20
54
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
6.7
170
1160
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
4.1
6.7
18
45
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
6.6
120
746
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.0
6.6
28
95
P80
ICPC
Personality disorder
12.4
6.6
11
9
F60.5
ICD-10 Finland
Anankastic personality disorder
6.3
6.5
16
26
TKC20
NOMESCO Finland
Catheterisation of bladder
2.6
6.5
38
154
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
6.5
62
312
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
6.4
41
173
IFA99, ,
SPAT
14.5
6.4
10
7
F39
ICD-10 Finland
Unspecified mood [affective] disorder
3.8
6.4
19
51
P72
ICPC
Schizophrenia
3.8
6.4
19
51
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
6.4
104
626
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.6
6.4
37
149
SPAT1241
SPAT
Extensive assessment of psychosocial situation
6.7
6.4
15
23
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
6.4
59
293
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
6.3
214
1560
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
3.3
6.3
23
71
F31.8
ICD-10 Finland
Other bipolar affective disorders
3.4
6.3
22
66
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
9.4
6.3
12
13
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
9.4
6.3
12
13
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.3
128
822
E46
ICD-10 Finland
Unspecified protein-energy malnutrition
+∞
6.3
6
*
3075A
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Other and unspecified disorders of eating[TARKEMMIN MÄÄRITTELEMÄTÖN SYÖMISHÄIRIÖ]
+∞
6.3
6
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
6.2
58
288
L04AX01
ATC
azathioprine; systemic
2.9
6.2
29
104
F50
ICD-10 Finland
Eating disorders
27.0
6.2
8
*
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.9
6.2
83
469
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.2
6.2
24
77
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
6.2
230
1711
N02AA05
ATC
oxycodone; systemic
1.8
6.2
94
554
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
6.2
89
516
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
7.8
6.1
13
17
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
6.1
68
361
ZY000
NOMESCO Finland
Hospital inpatient
4.2
6.1
16
39
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
6.1
78
435
P73
ICPC
Affective psychosis
12.7
6.1
10
8
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
6.0
45
204

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
168
614
3.41
36.63
8.1
6.4
1.06
1.06
mmol/l
0.14
156
566
146
554
3.16
29.29
2.3
2.0
396.84
384.62
nmol/l
0.32
138
515
257
1375
2.52
26.13
2.9
2.3
2.64
2.87
mg/l
0.87
229
1170
332
2087
2.32
22.43
7.8
4.7
35.27
36.42
g/l
2.78
318
1967
290
1743
2.28
21.54
4.6
3.1
2.35
2.36
mmol/l
0.50
258
1599
114
443
2.94
21.45
3.1
2.6
0.21
0.22
g/l
0.64
98
418
362
2419
2.25
20.34
10.6
7.2
1.21
1.22
mmol/l
0.39
328
2086
121
506
2.74
19.74
3.9
3.1
1.59
1.82
%
1.72
110
453
329
2153
2.17
19.00
9.8
6.9
1.21
1.22
mmol/l
0.40
313
1987
260
1556
2.18
18.84
3.9
2.5
60.17
60.58
u/l
0.04
244
1446
375
2595
2.18
18.60
7.9
6.0
9.78
10.85
umol/l
1.93
360
2470
322
2105
2.14
18.46
2.4
2.0
96.58
97.58
pmol/l
0.13
185
1097
416
3008
2.24
18.35
17.0
9.0
3.84
4.02
e9/l
0.91
369
2617
239
1400
2.17
18.13
2.1
1.7
19.67
20.59
nmol/l
0.43
211
1190
245
1451
2.16
18.05
5.7
3.9
7.39
7.40
ph
0.24
182
1009
258
1585
2.10
17.03
4.2
2.9
—
—
—
0
0
210
1194
2.17
16.96
6.0
4.0
—
—
—
0
0
241
1446
2.11
16.91
2.7
2.1
154.61
207.71
u/l
0.58
231
1377
149
737
2.36
16.85
2.7
2.4
2.25
2.38
g/l
1.54
131
680
158
805
2.31
16.66
2.7
2.5
13.37
13.42
umol/l
0.02
142
749
272
1718
2.07
16.53
9.8
6.2
—
—
—
0
0
380
2711
2.09
16.52
10.8
6.2
0.56
0.55
e9/l
0.46
334
2343
379
2721
2.06
15.94
10.9
6.2
0.04
0.04
e9/l
0.84
336
2349
148
751
2.29
15.65
2.1
1.6
1174.73
1180.39
nmol/l
0.03
131
564
387
2814
2.05
15.53
11.6
6.5
0.17
0.18
e9/l
0.54
350
2470
382
2774
2.03
15.27
11.0
6.2
1.78
1.97
e9/l
2.88
347
2460
136
700
2.22
13.73
1.3
1.2
—
—
—
0
0
346
2490
1.92
13.46
10.7
6.3
8.74
8.53
%
0.74
331
2342
345
2486
1.91
13.31
10.7
6.2
0.64
0.68
%
0.70
326
2325
336
2411
1.89
13.02
3.5
2.6
79.86
76.60
nmol/l
1.18
312
2201
87
378
2.52
12.86
3.0
2.8
67.19
72.56
e9/l
0.67
62
275
438
3438
2.01
12.85
7.0
4.6
820.13
2922.35
e6/l
—
8
48
343
2490
1.88
12.68
10.6
6.2
2.60
2.77
%
0.75
328
2336
295
2058
1.85
12.22
12.2
11.2
1.16
1.18
inr
0.32
255
1699
344
2521
1.85
12.12
10.5
6.1
57.34
56.76
%
0.39
330
2404
347
2550
1.85
12.12
10.5
6.2
27.90
28.83
%
0.89
334
2428
127
666
2.15
12.11
2.8
2.5
25.54
22.41
%
0.53
116
624
470
3817
2.06
12.06
11.4
7.4
77.76
77.48
u/l
0.04
457
3612
95
455
2.29
11.26
5.6
9.6
7.41
7.41
ph
0.11
57
255
41
127
3.39
11.16
3.7
1.7
—
—
—
0
0
94
451
2.29
11.09
5.6
9.5
1.38
0.85
mmol/l
0.49
83
379
371
2842
1.80
10.72
4.8
3.2
110.01
85.83
ug/l
1.36
355
2674
162
966
1.93
10.70
3.6
2.5
2.44
2.44
mmol/l
0.08
139
868
376
2894
1.80
10.66
7.0
5.1
6.44
6.47
mmol/l
0.11
351
2691
313
2292
1.76
10.46
4.4
3.3
6.46
6.23
ph
3.27
181
1297
255
1762
1.78
10.41
4.8
3.1
27.38
29.97
u/l
0.81
244
1681
83
392
2.30
10.13
7.5
10.3
—
—
—
0
0
220
1492
1.75
9.35
1.5
1.4
0.60
1.95
u/ml
2.52
69
402
436
3572
1.80
9.33
6.1
4.4
—
3.26
—
0
6
120
675
1.97
9.28
2.1
2.1
—
—
—
0
0
108
595
1.99
8.84
7.0
7.9
103.69
104.28
mmol/l
0.60
108
595
359
2813
1.69
8.72
5.3
3.7
0.00
0.00
estimate
0.50
69
583
363
2863
1.68
8.51
5.3
3.8
0.00
0.01
estimate
0.79
71
558
87
450
2.09
8.44
7.7
5.6
2.39
1.62
mmol/l
0.78
77
375
52
216
2.54
8.40
4.2
1.8
—
—
—
0
0
228
1601
1.68
8.32
5.2
3.1
37.32
91.54
e6/l
0.68
182
1199
169
1093
1.76
8.32
4.3
2.5
8.46
7.41
e6/l
0.26
156
989
247
1773
1.67
8.28
4.3
3.5
68.80
93.87
ng/l
0.17
166
1092
81
412
2.12
8.21
7.5
5.0
4.07
4.56
kpa
2.09
81
400
360
2848
1.66
8.20
5.3
3.7
0.08
5.14
estimate
0.78
74
590
88
468
2.03
7.91
7.6
5.5
7.37
7.38
ph
0.46
52
268
118
694
1.87
7.90
3.2
2.1
29.63
29.17
s
0.43
113
678
154
988
1.75
7.73
2.3
1.7
468.66
23709350.98
pmol/l
1.05
140
852
428
3573
1.69
7.62
5.0
3.3
35.97
37.98
u/l
0.38
411
3401
41
159
2.69
7.61
1.4
1.4
271.66
316.08
ug/g
0.84
29
86
128
787
1.80
7.40
2.9
2.5
146.69
94.89
ug/g
0.63
105
619
45
186
2.53
7.36
1.3
2.1
1.37
1.40
g/l
0.10
38
162
101
581
1.89
7.21
2.0
1.7
—
—
—
0
0
65
323
2.14
6.98
2.2
2.5
2.73
5.25
ug/l
3.07
59
280
182
1251
1.65
6.98
5.1
3.7
1.02
1.02
kg/l
0.33
128
821
188
1310
1.63
6.80
1.9
1.5
2.07
2.20
g/l
0.46
113
812
194
1368
1.62
6.67
5.0
3.0
0.44
0.43
e6/l
0.03
145
975
45
197
2.39
6.53
1.8
1.5
8.06
10.08
u/l
0.53
37
159
71
376
2.01
6.44
3.8
4.2
92.05
76.10
ng/l
0.43
64
331
64
330
2.05
6.25
6.5
4.7
7.40
7.41
ph
0.90
57
269
18
36
5.12
6.22
1.6
1.3
7921.08
1972.60
e6/l
0.68
13
25
36
146
2.56
6.14
1.9
2.2
210.01
339.96
ug/l
0.71
36
133
213
1562
1.56
6.10
10.4
5.8
—
—
—
0
0
252
1919
1.54
6.09
6.2
3.8
71.16
71.33
e6/l
0.00
186
1282
179
1262
1.60
6.07
2.7
2.2
—
—
—
0
0
86
496
1.86
6.06
2.8
2.4
45.59
33.63
u/l
0.58
75
414
154
2108
0.64
5.40
3.1
2.9
—
—
—
0
0
14
28
5.09
4.97
1.8
1.3
—
—
—
0
0
45
223
2.10
4.90
2.4
2.3
—
—
—
0
0
72
421
1.81
4.86
3.9
4.8
0.18
0.17
%
0.01
28
103
178
1309
1.51
4.84
7.1
4.6
—
—
—
0
0
54
288
1.96
4.82
3.4
2.4
—
—
—
0
0
15
34
4.50
4.77
1.4
1.3
35031.11
40073.72
e6/l
—
9
18
172
1261
1.51
4.73
3.0
3.3
1885.98
1063.39
ng/l
1.65
150
1045
474
4247
1.55
4.57
6.6
4.6
14.57
14.53
pmol/l
0.13
453
3942
15
36
4.25
4.54
1.7
1.5
1.35
1.35
promille
—
10
28
114
773
1.59
4.43
4.0
2.9
4.27
3.25
e6/l
0.44
56
354
73
441
1.75
4.42
3.8
4.7
0.79
1.06
%
0.47
29
124
70
418
1.76
4.41
3.8
4.5
1.21
0.79
%
0.29
29
112
39
192
2.10
4.34
4.5
3.8
36.91
36.91
°c
0.01
39
192
12
24
5.08
4.33
1.4
1.7
—
—
—
0
0
180
1357
1.47
4.25
2.2
2.0
—
—
—
0
0
14
41
3.47
4.20
1.5
1.2
6.42
6.03
mmol/l
0.16
14
36
267
2169
1.42
4.19
5.5
3.6
0.03
0.02
estimate
0.12
61
489
14
42
3.39
4.06
5.1
4.5
—
—
—
0
0
134
962
1.51
4.01
3.9
2.7
512.31
523.57
mosm/kgh2o
0.21
116
839
94
627
1.59
3.90
4.6
3.3
4.89
4.57
e9/l
0.14
84
561
16
54
3.02
3.87
2.5
3.0
—
—
—
0
0
294
2451
1.39
3.87
3.1
2.7
—
—
estimate
—
0
0
45
244
1.91
3.86
2.3
1.6
0.39
0.29
mg/l
0.37
23
95
49
274
1.86
3.84
3.5
1.6
—
—
—
0
0
214
1693
1.41
3.82
2.8
2.2
—
—
—
0
0
197
1536
1.42
3.82
6.5
3.8
0.00
0.00
estimate
0.50
66
554
44
238
1.92
3.81
3.5
1.6
—
—
—
0
0
27
121
2.29
3.79
4.0
3.7
1.36
2.49
ratio
0.84
17
67
21
84
2.55
3.75
6.9
2.3
—
—
—
0
0
13
34
3.88
3.71
1.5
1.5
1.80
1.99
umol/l
0.58
13
29
19
73
2.66
3.67
1.9
1.5
20.53
27.09
ng/l
0.58
19
73
20
79
2.58
3.66
5.1
2.1
16.79
16.32
%
0.36
20
79
13
35
3.77
3.61
1.2
1.1
—
—
—
0
0
15
51
2.99
3.59
1.8
2.0
—
—
—
0
0
49
280
1.82
3.59
2.9
2.9
260.08
161.61
ng/l
0.63
43
255
55
326
1.76
3.58
13.5
10.9
25.31
24.62
mmol/l
0.56
55
326
10
21
4.82
3.57
5.8
5.8
116.80
134.18
umol/l
—
5
11
540
5058
1.67
3.55
29.1
15.5
3.92
3.94
mmol/l
1.36
534
4939
51
297
1.78
3.52
3.4
1.6
—
—
—
0
0
51
298
1.78
3.48
3.4
1.6
—
—
—
0
0
14
47
3.03
3.43
2.9
1.6
91.54
90.72
%
0.25
14
47
51
300
1.76
3.41
3.4
1.6
—
—
—
0
0
75
490
1.61
3.40
1.7
1.4
18.96
24.43
iu/l
1.00
66
422
13
38
3.47
3.33
1.5
1.3
—
—
—
0
0
77
509
1.59
3.33
1.3
1.2
—
—
—
0
0
114
825
1.47
3.25
1.4
1.4
233.04
546.89
titre
6.45
23
183
43
244
1.82
3.24
6.4
5.2
—
—
—
0
0
50
299
1.73
3.17
1.4
1.3
—
—
—
0
0
119
875
1.45
3.12
4.6
3.4
304.82
226.68
ng/l
0.17
83
584
26
126
2.11
3.07
3.0
3.1
1.01
2.15
index
1.04
13
68
41
235
1.80
3.01
1.6
2.0
7.81
10.64
nmol/l
1.10
34
217
40
665
0.57
2.97
2.4
1.9
—
—
—
0
0
33
179
1.89
2.88
4.0
3.3
1502.55
273.17
mg/l
0.48
20
70
89
629
1.49
2.85
1.9
1.4
—
—
—
0
0
65
429
1.58
2.84
4.5
5.1
0.05
0.21
%
0.75
22
96
58
373
1.61
2.82
2.4
2.1
22230.12
4097.35
u/l
0.76
14
159
26
131
2.03
2.79
6.3
2.5
7.41
7.41
ph
0.27
26
131
84
591
1.49
2.75
3.8
2.8
4.39
5.45
umol/l
1.48
71
515
5
6
8.39
2.75
2.0
1.0
—
—
—
0
0
5
6
8.39
2.75
1.6
3.0
—
—
—
0
0
48
296
1.68
2.75
2.7
1.6
—
—
—
0
0
7
14
5.04
2.73
1.6
1.8
—
—
—
0
0
539
5107
1.54
2.65
26.4
13.6
23.72
20.96
mg/l
1.35
438
4128
14
55
2.58
2.63
3.9
1.9
—
—
—
0
0
58
381
1.58
2.60
1.2
1.2
—
—
—
0
0
11
36
3.09
2.57
1.6
2.8
—
—
—
0
0
192
1573
1.32
2.57
4.5
3.3
6.51
7.60
mmol/l
2.88
175
1351
193
1583
1.32
2.56
3.1
3.0
0.00
0.06
—
5
32
20
95
2.14
2.51
4.0
3.6
4.33
4.16
e9/l
0.10
20
95
18
82
2.23
2.49
1.8
1.6
—
—
—
0
0
40
242
1.70
2.48
1.2
1.2
0.18
1.95
u/ml
—
5
15
279
2416
1.29
2.45
17.7
10.4
0.00
0.00
e9/l
1.04
231
1971
52
338
1.59
2.45
1.2
1.1
—
86.78
—
0
9
22
110
2.04
2.44
11.6
7.9
56.16
61.69
%
0.60
22
110
62
421
1.53
2.42
7.3
3.8
7.38
7.34
ph
1.78
56
300
6
12
5.04
2.40
1.8
1.8
—
—
—
0
0
15
65
2.34
2.33
4.3
1.7
—
—
—
0
0
18
85
2.15
2.31
7.1
2.3
9.05
8.66
kpa
0.35
18
85
18
85
2.15
2.31
7.1
2.3
5.04
4.94
kpa
0.29
18
85
62
426
1.51
2.30
4.8
2.6
9.32
10.16
g/l
0.83
56
393
6
13
4.65
2.27
1.0
1.2
3.04
1.38
u/ml
—
6
13
45
289
1.60
2.24
2.8
1.7
—
—
—
0
0
9
29
3.13
2.23
1.9
2.8
1265.33
601.93
u/ml
—
9
29
5
9
5.59
2.21
1.6
1.4
—
—
—
0
0
12
48
2.53
2.19
1.8
1.4
—
—
—
0
0
553
5302
1.54
2.18
16.9
10.8
22.81
24.60
u/l
2.17
547
5165
20
101
2.01
2.18
7.2
2.4
11.48
7.94
pmol/l
0.65
20
101
14
61
2.33
2.16
1.4
1.8
0.67
0.87
%
—
9
36
56
382
1.51
2.16
6.8
3.8
1.21
1.23
mmol/l
0.93
45
327
10
36
2.81
2.14
1.5
1.6
—
—
—
0
0
12
49
2.48
2.11
1.8
2.6
0.28
1.15
g/24h
—
7
35
8
25
3.23
2.10
1.6
2.2
211.38
166.96
nmol/l
—
8
25
15
301
0.49
2.10
1.1
1.1
—
—
—
0
0
21
110
1.94
2.08
2.2
1.4
5546.50
16240.63
e6/l
0.91
14
75
29
169
1.75
2.08
1.3
1.3
—
—
—
0
0
27
154
1.79
2.07
10.9
2.4
24.28
24.61
mmol/l
0.14
27
154
146
1184
1.31
2.06
4.5
2.8
287.49
320.25
umol/l
3.54
130
1065
94
717
1.37
2.00
1.7
1.6
—
—
—
0
0
23
127
1.84
1.96
4.0
3.3
59.93
58.69
%
0.16
23
127
14
64
2.22
1.95
5.9
1.9
—
—
—
0
0
515
4893
1.37
1.95
8.0
5.5
1.74
1.82
mu/l
0.85
493
4593
10
39
2.59
1.95
2.1
1.6
64.60
53.32
%
—
5
25
368
3352
1.25
1.94
4.5
3.6
—
0.20
—
0
5
39
583
0.65
1.90
1.2
1.3
—
—
—
0
0
34
214
1.62
1.86
1.3
1.2
—
—
—
0
0
573
5561
1.65
1.85
39.3
21.0
4.27
4.47
e12/l
19.96
564
5460
21
115
1.86
1.85
4.2
1.7
—
—
—
0
0
573
5563
1.64
1.82
39.4
21.1
6.49
6.71
e9/l
1.82
564
5457
17
87
1.98
1.81
1.4
1.2
—
—
—
0
0
135
1102
1.29
1.81
1.4
1.3
19.88
27.51
iu/ml
0.60
35
333
139
1139
1.29
1.81
1.8
1.7
—
—
—
0
0
11
48
2.32
1.71
1.5
1.3
—
—
—
0
0
572
5559
1.60
1.70
39.4
21.1
259.34
259.20
e9/l
0.02
564
5471
24
142
1.72
1.67
3.8
1.5
481.17
451.39
mg/l
0.14
24
135
8
31
2.60
1.66
1.3
1.2
224.63
139.15
iu/ml
—
8
31
34
221
1.57
1.66
4.8
2.3
20.00
20.59
s
0.47
28
199
14
69
2.05
1.65
2.3
1.6
—
—
—
0
0
14
69
2.05
1.65
2.3
1.6
—
—
—
0
0
14
69
2.05
1.65
2.3
1.6
—
—
—
0
0
14
69
2.05
1.65
2.3
1.6
—
—
—
0
0
11
49
2.27
1.64
1.2
1.1
0.23
0.22
u/ml
—
5
22
15
77
1.97
1.60
1.3
1.4
—
—
—
0
0
32
207
1.58
1.60
1.5
1.7
8.32
6.70
u/ml
—
5
55
58
425
1.40
1.59
2.8
2.7
6.26
6.17
ph
0.31
36
279
146
1222
1.26
1.59
2.4
1.8
1.49
1.18
mg/l
0.35
104
933
547
5280
1.40
1.58
21.4
12.1
—
—
—
0
0
16
85
1.91
1.56
1.6
1.4
86.09
65.25
mmol/l
0.67
11
73
498
4748
1.29
1.53
5.3
4.5
5.81
5.77
mmol/l
0.20
467
4399
6
21
2.88
1.51
2.2
3.0
52.40
88.90
ug/l
—
6
21
61
456
1.38
1.50
1.5
1.4
—
—
—
0
0
26
164
1.61
1.45
1.4
1.2
—
—
—
0
0
5
16
3.14
1.44
1.0
1.5
—
—
—
0
0
5
16
3.14
1.44
1.6
1.2
0.00
0.00
estimate
—
5
16
10
46
2.19
1.40
7.5
2.2
44.56
44.05
%
—
10
46
32
215
1.52
1.38
1.7
1.2
—
—
—
0
0
35
498
0.68
1.38
1.5
1.7
3.34
3.36
mmol/l
0.03
20
354
36
250
1.47
1.34
1.4
1.9
4.26
9.61
iu/ml
—
7
61
26
169
1.56
1.31
1.6
2.1
3.51
4.45
iu/l
0.21
12
67
23
145
1.61
1.31
1.5
1.4
0.31
0.36
nmol/l
0.08
14
118
74
586
1.30
1.27
1.3
1.3
—
—
—
0
0
121
1020
1.23
1.24
1.5
1.3
5.21
8.54
u/ml
0.75
44
409
483
4622
1.23
1.22
4.1
3.9
1.14
1.22
mmol/l
2.03
454
4304
14
78
1.81
1.22
1.9
4.0
214.64
355.90
u/ml
0.17
14
73
21
132
1.61
1.22
1.2
1.2
—
—
—
0
0
5
19
2.64
1.22
1.8
2.1
—
—
—
0
0
8
37
2.18
1.22
1.1
1.1
480.75
417.56
nmol/l
—
8
32
66
829
0.77
1.20
1.8
1.5
—
—
—
0
0
55
422
1.33
1.18
3.5
4.0
23.81
19.00
ug/l
0.12
44
338
0
34
0.00
1.16
0.0
1.5
—
—
—
0
0
7
31
2.27
1.10
1.6
2.4
12.56
8.51
mmol/l
—
7
31
14
81
1.75
1.09
1.8
1.5
—
—
—
0
0
58
458
1.29
1.04
2.1
2.1
0.00
0.03
estimate
—
10
107
5
22
2.28
1.03
1.0
1.5
119.20
143.32
nmol/l
—
5
22
7
35
2.01
1.00
1.6
1.1
—
—
—
0
0
5
23
2.18
0.98
1.0
1.1
181.30
170.12
mmol/24h
—
5
23
19
124
1.55
0.98
2.7
1.4
—
—
—
0
0
182
1632
1.17
0.95
5.0
3.2
4.03
0.01
estimate
0.49
62
476
33
243
1.38
0.95
1.7
2.2
0.00
0.01
estimate
0.49
11
86
42
541
0.76
0.95
1.6
1.4
—
—
—
0
0
10
55
1.83
0.92
1.1
1.2
—
—
—
0
0
476
4585
1.18
0.92
6.1
5.6
37.98
38.22
mmol/mol
0.22
452
4352
8
43
1.87
0.87
1.1
1.1
—
—
—
0
0
460
4428
1.17
0.85
31.5
16.8
13.57
13.49
%
0.71
455
4381
53
427
1.26
0.84
7.5
3.7
—
—
—
0
0
31
233
1.35
0.81
1.7
1.8
—
—
—
0
0
8
47
1.71
0.81
1.0
1.1
86.63
113.04
pmol/l
—
8
47
58
476
1.24
0.80
1.4
1.3
82.95
159.39
u/ml
1.77
21
191
51
413
1.26
0.79
1.5
1.4
—
—
—
0
0
6
34
1.77
0.76
2.2
1.4
85.50
73.76
umol/l
—
6
34
101
880
1.18
0.76
1.9
1.8
—
—
—
0
0
5
24
2.09
0.74
1.2
2.6
13.46
16.07
%
—
5
24
9
55
1.65
0.73
1.2
1.2
—
—
—
0
0
15
101
1.50
0.70
1.0
1.0
1.62
2.10
eliau/ml
—
6
48
9
58
1.56
0.70
1.2
1.2
—
—
—
0
0
13
85
1.54
0.69
2.5
2.4
18.14
69.34
ug/min
—
7
49
11
69
1.61
0.68
1.2
1.1
—
—
—
0
0
5
94
0.53
0.67
3.0
3.0
6.08
7.62
mmol/l
—
5
89
508
4954
1.16
0.67
5.2
5.1
2.62
2.76
mmol/l
3.52
480
4661
5
28
1.79
0.66
1.2
1.3
—
—
—
0
0
14
95
1.48
0.64
1.1
1.1
—
—
—
0
0
6
104
0.57
0.62
1.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
2.9
—
1.18
—
0
21
10
65
1.55
0.55
1.5
1.2
—
—
—
0
0
6
37
1.63
0.55
1.7
2.9
—
—
—
0
0
20
151
1.34
0.54
14.2
7.8
—
—
—
0
0
6
38
1.58
0.54
1.0
1.7
—
—
—
0
0
74
650
1.16
0.53
1.4
1.2
—
—
—
0
0
6
40
1.50
0.51
1.2
1.0
210.33
217.09
mg/l
—
6
35
28
228
1.24
0.46
1.9
1.3
—
—
—
0
0
176
1651
1.09
0.43
1.5
1.6
—
—
—
0
0
5
32
1.57
0.42
5.8
3.3
0.20
0.78
index
—
5
32
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
27.47
—
0
17
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
173.19
—
0
18
499
4902
1.11
0.39
4.8
4.6
4.61
4.71
mmol/l
1.47
472
4626
12
89
1.36
0.38
1.1
1.0
—
—
—
0
0
6
42
1.43
0.35
1.5
1.1
36.17
32.77
mg/l
—
6
32
9
123
0.73
0.35
1.7
1.1
—
—
—
0
0
9
123
0.73
0.35
1.7
1.1
—
—
—
0
0
6
45
1.34
0.34
1.0
1.2
—
—
—
0
0
223
2134
1.07
0.33
2.2
2.1
—
—
—
0
0
21
253
0.82
0.33
1.2
1.3
100.94
261.20
miu/ml
—
8
134
146
1378
1.08
0.32
4.3
3.4
49.63
51.49
mg/l
0.05
104
871
496
4885
1.09
0.31
4.7
4.5
1.58
1.52
mmol/l
2.52
464
4588
8
63
1.27
0.28
1.3
2.1
5.53
64.71
u/ml
—
8
63
8
64
1.25
0.27
1.1
1.3
—
—
nmol/l
—
0
0
5
75
0.66
0.26
1.8
2.1
—
—
—
0
0
10
127
0.78
0.25
2.7
2.3
—
—
—
0
0
15
123
1.23
0.25
2.4
1.3
16.25
2.96
ug/l
0.81
15
108
9
76
1.19
0.24
1.1
1.4
0.56
0.52
nmol/l
—
9
70
147
1403
1.06
0.24
5.0
4.1
15.13
8.98
mg/mmol
0.60
104
852
11
88
1.25
0.22
1.1
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
10.01
—
0
12
5
43
1.16
0.21
1.0
1.0
—
—
—
0
0
9
112
0.80
0.20
2.6
4.1
—
—
—
0
0
24
268
0.89
0.17
1.1
1.1
—
—
—
0
0
16
184
0.87
0.17
1.1
1.3
—
—
—
0
0
8
68
1.18
0.16
1.0
1.3
—
—
—
0
0
10
83
1.21
0.15
1.9
1.1
—
6004.24
—
0
21
12
102
1.18
0.15
1.2
1.2
—
—
—
0
0
211
2062
1.04
0.14
2.0
1.9
1.27
1.32
mmol/l
0.22
178
1796
12
137
0.87
0.12
1.7
1.9
—
—
—
0
0
70
671
1.05
0.11
5.6
5.4
2.33
2.62
ug/l
0.15
63
593
37
393
0.94
0.11
2.4
3.1
0.55
0.77
ug/l
1.97
26
241
18
163
1.11
0.11
1.4
1.1
2.57
2.60
u/ml
0.01
12
85
6
72
0.83
0.07
1.0
1.2
19.55
17.37
u/l
—
6
61
16
174
0.92
0.07
1.3
1.4
206.00
155.29
pmol/l
0.18
16
169
9
87
1.04
0.07
1.1
1.8
2.89
4.90
mmol/24h
—
9
76
10
89
1.13
0.07
1.1
1.0
—
—
—
0
0
37
355
1.05
0.06
3.8
2.5
49.32
38.25
u/ml
0.22
37
339
48
496
0.96
0.05
1.6
1.6
960.79
975.32
mu/l
0.04
37
415
15
140
1.07
0.04
1.2
1.1
6.83
5.71
u/ml
—
8
70
22
230
0.95
0.03
1.8
1.5
—
—
—
0
0
17
161
1.06
0.03
1.5
1.1
—
—
—
0
0
29
300
0.96
0.03
1.7
1.6
74.24
59.41
ug/l
0.87
22
254
36
369
0.97
0.02
1.6
1.7
—
—
—
0
0
14
133
1.05
0.01
1.0
1.1
0.12
1.10
u/ml
—
7
65
11
116
0.95
0.00
2.9
2.8
1.35
1.54
mmol/l
0.26
11
111
22
226
0.97
0.00
1.7
1.5
1.16
1.31
mm
0.59
12
164
11
115
0.96
0.00
1.0
1.0
4.56
2.74
u/ml
—
6
48
23
235
0.98
0.00
1.8
1.6
—
—
—
0
0
13
133
0.98
0.00
1.2
1.1
0.15
0.92
u/ml
—
6
55
0
5
0.00
-0.00
0.0
4.0
—
10.60
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
59
1.02
-0.00
3.7
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
28.60
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
333.60
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
79.14
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
56.00
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.1
1.3
0.23
0.17
nmol/l
—
7
46
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
20.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
179.17
—
0
6
0
6
0.00
-0.00
0.0
4.5
—
7.22
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint R18_ANOREXIA and mortality.

Females

Parameter HR [95% CI] p-value
R18_ANOREXIA 2.716 [2.11, 3.49] < 0.001
Birth year 0.993 [0.98, 1.0] 0.099

During the follow-up period (1.1.1998 — 31.12.2019), 508 out of 2219 females with R18_ANOREXIA died.

Males

Parameter HR [95% CI] p-value
R18_ANOREXIA 3.85 [2.44, 6.09] < 0.001
Birth year 0.987 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 358 out of 1088 males with R18_ANOREXIA died.

Mortality risk

Mortality risk for people of age

years, who have R18_ANOREXIA.

N-year risk Females Males
1 0.251% 0.774%
5 1.631% 4.47%
10 3.628% 10.666%
15 6.819% 19.76%
20 11.606% 31.491%

Relationships between endpoints

Index endpoint: R18_ANOREXIA – Anorexia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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