Anisometropia and aniseikonia

H7_ANISOMETROPIA

obsolete_refractive error: ['Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus.']

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H52.3
  • Hospital discharge: ICD-9 3673
  • Hospital discharge: ICD-8 37002
  • Cause of death: ICD-10 H52.3
  • Cause of death: ICD-9 3673
  • Cause of death: ICD-8 37002

2 out of 7 registries used, show all original rules.

1390

4. Check minimum number of events

None

1390

5. Include endpoints

None

1390

6. Filter based on genotype QC (FinnGen only)

1250

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H52
Name in latin
Anisometropia sive aniseiconia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13920 7671 6203
Only index persons 10627 5992 4635
Unadjusted period prevalence (%)
Whole population 0.20 0.22 0.17
Only index persons 0.20 0.22 0.18
Median age at first event (years)
Whole population 13.02 16.52 8.40
Only index persons 23.43 30.46 14.34

-FinnGen-

Key figures

All Female Male
Number of individuals 1250 805 445
Unadjusted period prevalence (%) 0.26 0.29 0.20
Median age at first event (years) 54.16 52.30 57.51

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1291
Matched controls
12908
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
11528.4
307.7
1125
7
H52.1
ICD-10 Finland
Myopia
35.1
307.7
227
78
H53.0
ICD-10 Finland
Amblyopia ex anopsia
52.7
237.6
137
29
H52.2
ICD-10 Finland
Astigmatism
34.5
194.7
125
40
H52.0
ICD-10 Finland
Hypermetropia
23.5
168.8
124
58
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
164.1
154
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.4
154.1
393
976
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.3
94.1
564
2450
H25.0
ICD-10 Finland
Senile incipient cataract
5.6
88.1
182
365
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.2
78.7
239
656
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.6
58.7
536
2766
H26.4
ICD-10 Finland
After-cataract
3.7
58.1
210
645
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.9
53.3
176
507
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
49.3
47
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.4
44.6
412
2087
H50.31
ICD-10 Finland
Intermittent exotropia
232.9
44.2
45
*
H26.02
ICD-10 Finland
Presenil cataract
6.3
44.0
76
127
H52.4
ICD-10 Finland
Presbyopia
6.3
42.2
73
122
H50.1
ICD-10 Finland
Divergent concomitant strabismus
+∞
40.8
39
*
S01BA07
ATC
fluorometholone; ophthalmic
8.5
39.1
51
62
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
108.5
38.9
42
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
37.4
611
3846
H25.8
ICD-10 Finland
Other senile cataract
3.0
36.5
182
672
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
35.6
34
*
CGD20
NOMESCO Finland
Laser-assisted in situ keratomileusis
+∞
34.5
33
*
WX140
NOMESCO Finland
Parabulbar anesthesy
3.9
33.0
100
269
XCK00
NOMESCO Finland
Perimetry
3.6
32.1
110
322
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
31.4
30
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
31.4
30
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
4.8
31.4
73
160
H50.2
ICD-10 Finland
Vertical strabismus
276.5
26.8
27
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
25.3
275
1446
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
4.5
22.8
56
128
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.3
22.6
183
851
CG2T4
NOMESCO Finland
Topography assessment of cornea
8.0
21.3
29
37
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
18.2
20.9
32
18
H50.52
ICD-10 Finland
Exophoria
21.9
20.9
30
14
H53.2
ICD-10 Finland
Diplopia
4.4
20.8
53
125
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
18.3
111
450
H50.51
ICD-10 Finland
Esophoria
67.6
17.8
20
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
16.7
16
*
H44.2
ICD-10 Finland
Degenerative myopia
38.5
15.4
19
5
ZXE00
NOMESCO Finland
One hour or less
1.6
15.0
494
3567
3673A
ICD-9 Finland
Disorders of refraction and accommodation, Anisometropia and aniseikonia
+∞
14.6
14
*
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
43.0
14.1
17
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
4.0
13.8
39
100
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.1
13.6
58
195
H26.2
ICD-10 Finland
Complicated cataract
5.3
13.5
27
52
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
13.1
160
865
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
4.3
12.7
33
79
S01ED51
ATC
timolol, combinations; ophthalmic
2.2
12.6
105
492
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
11.6
114
569
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
11.5
11
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
11.5
11
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
121.0
11.4
12
*
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
+∞
10.4
10
*
H50.8
ICD-10 Finland
Other specified strabismus
+∞
10.4
10
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.0
10.3
114
595
37600
ICD-8 Finland
Detachment of retina, Primaria
23.6
10.2
14
6
ZXD20
NOMESCO Finland
Day surgery
1.8
10.2
158
921
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.2
10.2
84
392
CKC12
NOMESCO Finland
Photocoagulation of retina
2.6
9.7
56
222
H40.0
ICD-10 Finland
Glaucoma suspect
2.0
9.5
98
499
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
3.9
9.4
27
70
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
9.4
152
898
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
9.4
9
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
9.4
9
*
Z3231
NOMESCO Finland
Registered nurse
1.5
8.8
333
2422
CKD40
NOMESCO Finland
Endophotocoagulation of retina
4.0
8.6
24
61
CS494
NOMESCO Finland
Other visual field testing
2.9
8.5
38
132
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.8
8.5
120
681
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
2.1
8.4
79
388
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
8.3
8
*
3503
FHL
Single muscle retroposition
+∞
8.3
8
*
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
8.3
8
*
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
8.3
8
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
2.5
8.3
49
197
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
33.6
8.1
10
*
S01EE01
ATC
latanoprost; ophthalmic
2.1
8.1
74
361
ZXA10
NOMESCO Finland
Bilateral
1.6
7.9
216
1460
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.1
7.7
31
101
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.8
7.6
121
710
H54.7
ICD-10 Finland
Unspecified visual loss
6.7
7.6
18
27
WX002
NOMESCO Finland
Sedation and analgesia
1.6
7.6
220
1509
SPAT1260
SPAT
Consultation of another employee
1.6
7.3
207
1410
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
7.3
7
*
H52.5
ICD-10 Finland
Disorders of accommodation
+∞
7.3
7
*
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
7.3
7
*
Z2221
NOMESCO Finland
Medical doctor
1.5
7.2
317
2365
H50.9
ICD-10 Finland
Strabismus, unspecified
30.2
7.2
9
*
S01ED01
ATC
timolol; ophthalmic
2.6
7.1
41
163
H53.8
ICD-10 Finland
Other visual disturbances
3.5
7.1
24
70
ZXA05
NOMESCO Finland
Left side
1.5
7.1
265
1916
H17.8
ICD-10 Finland
Other corneal scars and opacities
13.9
6.9
11
8
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
40.3
6.8
8
*
114
Kela drug reimbursment
Glaucoma
1.8
6.7
96
547
ZXA00
NOMESCO Finland
Right side
1.4
6.6
289
2150
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
12.3
6.6
11
9
H26.9
ICD-10 Finland
Cataract, unspecified
3.4
6.6
23
69
F43
ICPC
Eye, Other diagnostic procedure
3.0
6.6
28
95
F29
ICPC
Eye symptom/complaint other
1.6
6.5
138
877
J20
ICD-10 Finland
Acute bronchitis
1.7
6.5
123
759
S01EC01
ATC
acetazolamide; systemic
2.9
6.5
29
101
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.5
896
8023
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
70.2
6.4
7
*
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.4
301
2267
S01AA01
ATC
chloramphenicol; ophthalmic
2.1
6.3
55
263
H54.5
ICD-10 Finland
Severe visual impairment, monocular
6.6
6.3
15
23
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
3.9
6.3
18
47
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
6.3
6
*
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.1
6.2
55
266
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.5
6.2
20
57
Z31.5
ICD-10 Finland
Genetic counselling
2.0
6.2
67
349
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
3.2
6.2
23
72
N03AG01
ATC
valproic acid; systemic, rectal
1.9
6.1
72
385
J45
ICD-10 Finland
Asthma
1.6
6.1
128
811
S01EA05
ATC
brimonidine; ophthalmic
2.7
6.1
31
116
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.7
6.0
30
111
S01BC03
ATC
diclofenac; ophthalmic
3.0
6.0
26
89

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
149
881
1.78
9.17
4.9
3.9
1.23
1.23
mmol/l
0.33
117
763
153
939
1.71
8.26
5.9
3.9
—
—
—
0
0
1120
10368
1.60
7.59
6.0
5.4
1.79
1.92
mu/l
3.57
1027
9645
982
8914
1.42
6.68
4.9
4.4
14.91
14.73
pmol/l
1.47
883
8192
623
5297
1.34
6.21
2.9
2.6
77.64
76.53
nmol/l
0.45
551
4809
49
228
2.19
6.06
4.7
4.0
2.51
2.37
mmol/l
0.15
31
146
621
5294
1.33
6.01
14.0
11.6
0.02
0.00
e9/l
0.47
491
4310
51
250
2.08
5.56
5.2
3.7
—
—
—
0
0
488
4066
1.32
5.36
7.1
6.7
—
—
—
0
0
45
215
2.13
5.25
6.5
3.2
8.04
8.05
pmol/l
0.00
45
215
499
4225
1.29
4.72
3.3
3.1
—
—
—
0
0
144
1003
1.49
4.57
4.0
5.3
0.27
0.17
%
0.16
37
255
132
906
1.51
4.50
2.4
3.1
65.73
66.65
g/l
0.81
119
840
923
8486
1.31
4.45
8.2
8.1
83.66
80.86
u/l
0.56
854
8061
289
2292
1.34
4.34
4.0
2.9
493.08
532.95
mosm/kgh2o
2.58
250
2016
173
1267
1.42
4.23
1.3
1.3
—
—
—
0
0
826
7508
1.28
4.23
3.6
3.4
47.87
46.31
u/l
0.12
762
7122
284
2255
1.33
4.22
1.9
1.7
479.06
26324586.49
pmol/l
1.96
205
1888
1064
10012
1.36
4.16
6.4
6.2
38.39
38.96
mmol/mol
1.49
971
9431
405
3383
1.29
4.14
4.6
3.3
0.01
0.03
estimate
0.33
147
1050
650
5760
1.26
4.04
7.9
7.5
1.22
1.22
mmol/l
0.08
525
5014
633
5600
1.26
3.96
7.3
6.8
0.68
0.68
%
0.03
591
5262
139
993
1.45
3.90
3.9
4.7
0.62
0.68
%
0.19
39
304
1163
11133
1.45
3.87
19.9
18.1
139.49
139.62
mmol/l
0.97
1137
10919
115
793
1.49
3.86
1.2
1.2
—
—
—
0
0
638
5665
1.25
3.81
6.9
6.6
55.97
56.49
%
0.52
611
5436
138
991
1.44
3.77
4.0
4.9
0.08
0.10
%
0.11
37
273
631
5604
1.25
3.74
7.2
6.7
2.96
2.86
%
0.50
592
5271
30
141
2.15
3.72
1.7
2.3
32.07
32.86
pg
0.51
30
141
143
1039
1.42
3.67
4.0
4.8
1.05
0.99
%
0.10
41
323
41
219
1.90
3.62
1.6
1.5
0.32
0.37
nmol/l
0.21
33
169
688
6183
1.24
3.61
4.8
4.0
0.04
0.25
estimate
0.40
178
1253
588
5195
1.24
3.61
8.6
6.9
1.22
1.21
mmol/l
0.36
531
4818
179
1357
1.37
3.58
1.8
1.7
—
—
—
0
0
478
4130
1.25
3.58
4.0
3.8
38.35
60.46
ng/l
0.67
319
2856
630
5613
1.24
3.56
7.3
6.8
8.88
8.75
%
0.42
587
5285
214
1670
1.34
3.55
2.4
2.6
102.69
124.63
ug/g
0.51
151
1318
1162
11154
1.42
3.48
20.1
18.3
3.96
3.96
mmol/l
0.17
1133
10917
122
870
1.44
3.47
1.4
1.3
204.84
334.93
u/ml
0.55
114
807
681
6140
1.23
3.37
4.7
3.9
9.46
3.69
estimate
0.26
183
1330
643
5773
1.23
3.28
7.1
6.7
29.26
28.65
%
0.72
611
5499
688
6224
1.23
3.25
7.0
7.0
0.20
0.19
e9/l
0.64
590
5410
102
713
1.47
3.23
1.3
1.3
48.10
51.37
au/ml
—
5
54
416
3572
1.24
3.23
2.8
2.6
53.90
82.88
u/l
0.71
366
3322
381
3241
1.25
3.21
1.7
1.7
21.38
20.54
nmol/l
0.49
300
2749
673
6083
1.22
3.18
4.8
3.9
0.00
0.00
estimate
0.50
180
1304
667
6035
1.22
3.08
6.8
6.6
0.04
0.04
e9/l
0.29
567
5150
66
425
1.58
3.06
14.8
7.7
1.38
1.36
mg/l
0.08
60
389
316
2646
1.26
3.04
4.8
4.8
—
—
—
0
0
389
3341
1.23
2.97
4.6
4.0
0.00
0.01
estimate
1.34
171
1219
57
357
1.62
2.97
1.4
1.2
26.88
28.37
u/ml
—
5
17
494
4350
1.22
2.97
2.1
2.2
—
—
—
0
0
665
6031
1.21
2.95
6.8
6.6
0.57
0.58
e9/l
0.50
568
5146
1192
11541
1.43
2.93
12.6
11.8
26.33
25.39
u/l
0.80
1140
11233
32
170
1.90
2.92
1.8
1.8
—
—
—
0
0
679
6178
1.21
2.89
6.9
6.6
1.88
1.98
e9/l
1.42
592
5412
108
781
1.42
2.88
2.6
2.5
6.79
23.13
au/ml
—
8
74
54
337
1.63
2.86
1.4
1.2
1.88
2.14
u/ml
—
5
28
383
3302
1.23
2.80
3.9
3.2
0.70
0.44
e6/l
0.41
270
2419
360
3084
1.23
2.80
1.4
1.4
3.50
1.84
u/ml
0.71
95
831
128
960
1.37
2.77
4.2
3.2
10.18
10.50
g/l
0.44
116
892
155
1200
1.33
2.73
2.5
2.2
356.06
385.40
nmol/l
1.02
141
1107
29
153
1.92
2.72
2.3
2.3
1.21
0.88
%
0.82
19
103
235
1928
1.27
2.67
3.1
2.6
13.48
13.13
umol/l
0.30
215
1807
319
2712
1.23
2.65
1.5
1.6
2.14
2.27
g/l
0.70
187
1644
119
889
1.37
2.64
1.3
1.2
140.72
148.29
u/ml
0.08
40
344
632
5743
1.20
2.63
3.7
3.1
116.82
108.92
ug/l
0.18
570
5388
388
3372
1.22
2.60
4.3
4.1
7.40
7.40
ph
0.49
255
2439
23
114
2.04
2.57
1.2
1.3
0.13
2.33
u/ml
2.33
11
58
26
135
1.94
2.56
4.3
2.8
23.92
21.78
nmol/l
0.23
26
128
643
5865
1.19
2.53
6.3
6.8
12.24
12.15
umol/l
0.04
590
5587
168
1330
1.30
2.53
3.5
3.0
1.78
1.79
%
0.06
132
1203
75
520
1.47
2.53
1.1
1.1
—
—
—
0
0
1198
11644
1.40
2.52
21.8
19.7
74.11
74.35
umol/l
0.08
1182
11519
549
4941
1.19
2.51
2.2
2.1
100.89
95.23
pmol/l
1.55
287
2588
139
1075
1.33
2.48
1.2
1.2
—
—
—
0
0
360
3119
1.21
2.47
2.5
2.4
2.81
2.84
mg/l
0.07
281
2691
1237
12099
1.53
2.47
26.5
23.6
6.69
6.78
e9/l
0.86
1201
11821
85
607
1.43
2.46
1.7
1.5
22.65
26.05
iu/l
0.47
69
494
218
1791
1.26
2.45
1.9
1.7
1253.92
1195.05
nmol/l
0.35
131
1342
729
6737
1.19
2.43
10.0
9.8
3.96
4.08
e9/l
0.69
630
5835
131
1008
1.33
2.42
4.4
4.2
7.39
7.35
ph
4.49
88
724
341
2946
1.21
2.40
4.2
4.4
91.35
90.04
%
0.47
330
2882
99
730
1.39
2.40
2.2
2.7
—
—
—
0
0
441
3904
1.20
2.40
3.4
3.5
2.36
2.36
mmol/l
0.17
397
3556
14
58
2.43
2.37
2.6
2.6
896.57
745.09
u/ml
0.19
14
58
101
753
1.37
2.30
3.4
3.3
4.49
4.59
pmol/l
0.48
91
662
1175
11409
1.33
2.28
16.1
13.7
—
—
—
0
0
124
958
1.33
2.24
1.4
1.5
—
—
—
0
0
57
384
1.51
2.24
1.6
1.6
9.12
9.66
u/l
0.13
45
279
1235
12094
1.48
2.23
26.4
23.5
90.70
90.61
fl
0.30
1218
11983
1235
12097
1.48
2.19
26.4
23.5
30.22
30.17
pg
0.47
1218
11985
1235
12097
1.48
2.19
26.5
23.6
4.46
4.48
e12/l
0.99
1200
11825
1235
12097
1.48
2.19
27.6
24.1
39.91
40.41
%
0.92
1218
11980
119
918
1.33
2.18
6.4
5.0
5.23
5.11
kpa
0.74
112
888
188
1541
1.26
2.16
1.3
1.2
—
—
—
0
0
11
42
2.63
2.14
2.1
2.1
—
—
—
0
0
1235
12102
1.47
2.13
26.7
23.8
133.67
134.29
g/l
0.82
1218
11986
1234
12093
1.46
2.09
26.5
23.6
260.10
254.70
e9/l
1.98
1204
11852
1096
10572
1.24
2.08
5.0
5.0
4.62
4.62
mmol/l
0.03
989
9923
78
568
1.40
2.07
1.6
1.7
—
—
—
0
0
116
901
1.32
2.04
6.4
5.0
7.41
7.41
ph
0.84
96
744
541
4926
1.17
2.04
3.9
3.5
6.22
6.24
ph
0.09
262
2776
199
1654
1.24
2.03
3.2
2.5
22.46
22.65
%
0.07
179
1555
129
1018
1.30
2.02
4.2
3.0
69.59
70.90
e9/l
0.14
92
742
13
57
2.29
1.98
2.6
3.9
0.25
0.30
e9/l
—
7
31
44
289
1.54
1.97
1.3
1.2
—
—
—
0
0
213
1791
1.23
1.95
3.1
2.5
2.41
2.34
g/l
1.00
191
1670
541
4940
1.16
1.94
5.1
5.3
35.91
35.89
g/l
0.02
487
4634
486
4402
1.17
1.93
4.8
4.0
224.04
94.04
e6/l
0.93
318
3047
1041
10009
1.21
1.93
4.3
4.2
1.25
1.27
mmol/l
0.41
933
9254
67
482
1.41
1.92
1.7
1.7
2.38
6.91
iu/ml
—
10
103
196
1643
1.23
1.86
1.5
1.3
895.79
526.65
titre
0.93
38
337
714
6671
1.16
1.85
6.0
5.3
6.50
6.62
mmol/l
0.79
664
6294
87
658
1.35
1.85
6.8
5.3
—
—
—
0
0
1142
11094
1.25
1.85
17.2
15.5
22.25
23.87
mg/l
0.88
926
9056
31
191
1.64
1.82
1.5
1.8
1.60
1.67
mmol/l
0.16
31
186
7
23
3.05
1.80
2.6
1.4
1.42
1.27
umol/l
—
7
16
58
416
1.41
1.72
2.9
2.1
—
—
—
0
0
1086
10512
1.21
1.71
5.1
4.9
1.49
1.47
mmol/l
0.73
983
9803
544
5004
1.15
1.71
14.8
14.3
1.24
1.23
inr
0.08
444
4170
52
367
1.43
1.68
2.7
2.6
—
—
—
0
0
76
573
1.35
1.67
3.1
2.3
4673.00
4756.69
u/l
0.01
26
223
415
3749
1.16
1.67
2.9
2.4
—
—
—
0
0
18
317
0.56
1.67
3.3
5.8
1.22
1.27
mmol/l
0.11
13
272
98
768
1.30
1.66
2.5
1.8
1.52
1.29
g/l
0.35
88
713
51
361
1.43
1.63
1.4
1.4
281.34
292.61
ug/g
0.17
30
218
1068
10333
1.19
1.63
5.1
4.9
5.79
5.89
mmol/l
2.16
940
9514
508
4664
1.15
1.62
1.9
1.9
1.30
1.35
mmol/l
0.71
390
3971
419
3795
1.15
1.62
3.9
3.3
31.89
76.05
e6/l
1.57
305
2889
24
143
1.69
1.61
1.8
2.2
—
—
—
0
0
293
2584
1.17
1.61
2.2
1.9
1.19
1.24
mg/l
0.09
213
1986
82
631
1.32
1.59
1.2
1.3
—
—
—
0
0
1103
10709
1.20
1.59
5.6
5.6
2.70
2.70
mmol/l
0.00
995
10015
314
2789
1.17
1.57
2.9
2.9
335.62
336.21
umol/l
0.03
265
2471
239
2734
0.85
1.57
3.8
3.9
1.02
1.57
kg/l
0.50
162
1838
500
4602
1.14
1.52
4.8
3.8
0.02
0.03
estimate
0.15
147
1093
221
1916
1.18
1.49
5.4
4.0
0.81
0.82
mmol/l
0.51
203
1820
63
472
1.35
1.47
3.1
1.9
1.43
1.52
g/l
0.31
51
426
379
3430
1.15
1.47
2.3
2.2
280.95
219.91
u/l
0.34
350
3274
169
1433
1.21
1.46
1.3
1.3
—
—
—
0
0
144
1205
1.22
1.42
2.0
1.9
3.22
3.47
ratio
1.79
111
922
6
139
0.43
1.39
1.3
2.2
12.73
13.22
%
—
6
139
17
96
1.78
1.39
1.4
1.7
—
—
—
0
0
248
2187
1.17
1.36
2.7
2.9
2.45
2.45
mmol/l
0.01
213
1962
115
951
1.23
1.29
1.6
1.4
—
—
—
0
0
10
48
2.09
1.28
1.3
1.3
172.15
183.25
pmol/l
—
10
48
218
1914
1.17
1.27
3.3
3.1
3.88
2.92
e6/l
0.46
93
933
21
130
1.63
1.27
1.4
1.3
—
—
—
0
0
9
44
2.05
1.27
1.0
1.1
149.33
196.72
iu/ml
—
9
44
394
3615
1.13
1.22
4.3
3.1
—
—
—
0
0
5
19
2.64
1.21
1.2
1.2
—
—
—
0
0
37
263
1.42
1.21
1.6
1.9
—
—
—
0
0
367
3355
1.13
1.21
3.9
3.1
0.00
0.03
—
10
70
39
283
1.39
1.15
1.1
1.1
—
—
—
0
0
55
422
1.32
1.15
1.7
1.9
—
—
—
0
0
26
175
1.50
1.13
2.7
4.0
1.17
1.55
%
0.42
18
162
419
3877
1.12
1.12
2.9
3.4
31.37
32.29
u/l
0.13
391
3687
43
320
1.36
1.10
1.0
1.1
1.50
8.29
eliau/ml
—
5
42
7
31
2.26
1.10
1.4
2.2
13.51
15.79
umol/l
—
7
31
271
2448
1.14
1.08
2.3
2.0
—
—
—
0
0
16
97
1.66
1.07
1.7
1.1
104.75
107.68
pmol/l
0.10
16
97
109
917
1.21
1.06
1.7
1.7
3.39
3.47
mmol/l
0.26
74
634
23
153
1.51
1.06
1.4
1.6
273.94
279.06
mosm/kgh2o
0.57
17
112
130
1115
1.18
1.03
2.6
2.6
0.20
0.21
g/l
0.61
119
1043
13
75
1.74
1.03
1.2
1.2
—
—
—
0
0
19
287
0.66
1.03
1.4
1.7
10440.54
13459.87
e6/l
0.20
13
212
69
850
0.80
1.02
2.1
2.4
6.68
7.14
ug/l
0.11
53
762
184
1626
1.15
1.01
8.5
6.2
1.12
1.08
mmol/l
1.04
171
1499
10
53
1.89
1.01
1.9
2.3
28.25
167.16
ug/l
—
10
48
186
1647
1.15
1.00
3.3
3.2
0.75
0.77
ug/l
0.18
125
1056
19
123
1.55
1.00
1.4
1.3
—
—
—
0
0
69
558
1.25
0.99
2.1
2.2
10.42
0.01
estimate
0.48
24
178
11
61
1.81
0.98
1.0
1.1
1213.45
1744.44
miu/ml
1.29
11
61
160
1403
1.16
0.98
1.4
1.5
—
—
—
0
0
28
199
1.42
0.96
1.3
1.7
0.60
0.82
g/l
0.62
22
161
160
1406
1.16
0.96
2.0
1.8
—
—
—
0
0
22
149
1.48
0.95
1.6
2.5
—
—
—
0
0
9
51
1.77
0.94
1.1
1.5
105.98
163.41
mmol/24h
—
9
51
331
3051
1.11
0.94
4.1
4.4
—
—
—
0
0
17
109
1.57
0.93
1.1
1.1
—
—
—
0
0
6
29
2.07
0.89
2.5
3.2
—
—
—
0
0
787
7588
1.09
0.86
4.4
4.0
—
6313.81
—
0
16
67
810
0.82
0.86
3.0
3.2
104.53
196.34
ng/l
4.37
59
750
57
461
1.25
0.84
1.8
1.6
371.83
302.46
mu/l
0.91
52
413
16
104
1.54
0.84
1.4
1.5
—
—
—
0
0
308
2848
1.11
0.83
2.9
2.4
—
—
—
0
0
21
146
1.45
0.82
2.3
2.5
—
—
—
0
0
34
258
1.33
0.82
3.3
2.0
—
—
—
0
0
6
32
1.88
0.82
1.0
1.0
26.17
32.43
iu/ml
—
6
32
15
97
1.55
0.81
1.1
1.2
27.00
39.56
mg/l
—
10
80
19
130
1.47
0.81
4.0
4.4
—
—
—
0
0
50
401
1.26
0.80
1.5
1.2
—
—
—
0
0
151
1342
1.14
0.79
2.7
3.3
11.40
7.69
umol/l
0.66
127
1166
235
2151
1.11
0.77
1.3
1.3
27.68
32.25
iu/ml
0.23
60
629
111
1268
0.86
0.77
11.1
8.0
7.43
7.41
ph
1.88
46
692
106
922
1.16
0.76
4.8
4.1
92.88
81.05
ng/l
0.26
82
824
14
91
1.54
0.75
1.1
1.0
—
—
—
0
0
24
175
1.38
0.75
1.0
1.1
1.95
4.75
eliau/ml
0.60
11
68
110
1254
0.87
0.74
11.1
8.0
0.26
0.80
mmol/l
0.77
94
1042
5
24
2.09
0.74
1.4
1.6
4.74
7.52
mmol/l
—
5
24
9
54
1.67
0.74
1.1
1.0
—
—
—
0
0
294
2729
1.10
0.74
5.5
5.5
2.73
2.85
ug/l
0.06
257
2472
6
109
0.55
0.72
1.0
2.4
—
—
—
0
0
36
282
1.28
0.71
1.7
1.9
11.48
36.66
e6/l
0.55
25
199
41
327
1.26
0.71
2.1
2.0
2.37
20.62
iu/l
0.55
14
138
5
26
1.93
0.70
1.6
2.0
—
—
—
0
0
15
101
1.49
0.70
1.3
1.4
155200.00
101939.11
e6/l
—
5
54
5
27
1.85
0.68
3.4
7.1
5.72
4.91
kpa
—
5
27
7
42
1.67
0.68
2.4
1.7
—
—
—
0
0
221
2033
1.10
0.67
1.9
1.7
—
—
—
0
0
57
476
1.21
0.66
2.8
3.0
21.38
21.09
s
0.20
48
434
94
821
1.16
0.66
2.4
2.3
13.48
11.98
nmol/l
0.79
86
738
36
286
1.27
0.65
1.8
1.9
1492.62
625.95
e6/l
0.39
26
214
343
3225
1.09
0.65
3.5
3.3
1400.38
1245.91
ng/l
0.27
286
2740
7
44
1.59
0.65
6.9
3.0
—
—
—
0
0
10
62
1.62
0.65
1.0
1.3
154.60
143.81
nmol/l
—
10
62
29
226
1.29
0.61
1.0
1.1
3.71
10.50
u/ml
1.30
14
106
30
235
1.28
0.61
1.0
1.1
2.09
6.39
u/ml
1.40
14
118
113
1265
0.88
0.61
10.9
4.7
1.46
1.71
mmol/l
0.28
98
1071
38
307
1.24
0.61
1.8
1.8
48.68
41.03
nmol/l
1.09
38
295
21
156
1.35
0.61
1.2
1.6
—
2640.00
—
0
5
27
209
1.30
0.60
1.0
1.1
2.55
0.36
u/ml
—
10
76
279
2610
1.09
0.60
3.4
2.6
7.03
6.76
e6/l
0.14
248
2375
117
1305
0.89
0.60
10.7
4.8
7.39
7.38
ph
0.95
69
766
57
482
1.19
0.60
2.6
1.7
—
—
—
0
0
46
381
1.21
0.60
2.9
2.5
10.48
10.76
g/l
0.17
40
345
8
52
1.54
0.59
1.0
1.0
3.75
3.30
kpa
—
8
41
8
53
1.51
0.58
1.0
1.0
6.24
7.78
kpa
—
8
42
8
53
1.51
0.58
1.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
2.2
—
—
—
0
0
7
114
0.61
0.58
1.1
1.1
—
—
—
0
0
24
184
1.31
0.58
1.3
3.0
13.68
9.33
umol/l
0.16
15
139
159
1453
1.11
0.57
1.9
1.6
—
—
—
0
0
554
5332
1.07
0.56
3.2
2.8
—
—
estimate
—
0
0
160
1465
1.10
0.55
2.5
3.4
3.96
5.06
e9/l
1.61
132
1284
15
205
0.73
0.54
1.1
1.1
—
—
—
0
0
30
240
1.26
0.54
1.0
1.1
—
—
—
0
0
17
125
1.36
0.53
1.1
1.2
—
—
—
0
0
17
126
1.35
0.51
21.5
7.5
11.04
10.83
%
0.09
17
126
220
2053
1.09
0.51
3.2
3.0
1.18
1.11
e6/l
0.09
96
1070
30
242
1.25
0.51
1.0
1.1
—
—
—
0
0
9
65
1.39
0.50
1.2
1.2
—
—
—
0
0
20
153
1.31
0.50
2.5
2.4
—
—
—
0
0
6
41
1.47
0.50
2.3
3.3
32.67
32.38
umol/l
—
6
30
32
261
1.23
0.50
1.1
1.1
7.31
16.91
au/ml
—
7
60
80
709
1.14
0.49
8.8
4.1
131.03
128.41
g/l
0.49
75
691
7
46
1.52
0.48
1.1
1.7
1.05
2.57
u/ml
—
7
46
42
355
1.19
0.47
1.7
4.1
43.96
63.08
mg/l
0.51
31
302
12
85
1.42
0.47
2.0
1.9
3.00
1.96
u/field
—
5
51
25
200
1.25
0.46
1.1
1.2
64.30
30.72
u/l
0.64
20
175
7
49
1.43
0.46
6.9
2.8
—
—
—
0
0
60
526
1.15
0.44
2.7
2.3
—
—
—
0
0
101
916
1.11
0.44
3.0
2.6
5.95
6.14
ph
1.34
55
621
19
148
1.29
0.43
1.5
1.3
—
—
—
0
0
108
985
1.11
0.43
1.5
1.3
—
—
—
0
0
363
3477
1.06
0.42
1.6
1.5
—
—
—
0
0
8
58
1.38
0.41
1.0
1.2
8.13
8.90
mm/h
—
8
58
0
15
0.00
0.41
0.0
1.3
—
1.73
—
0
15
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.02
—
0
17
0
17
0.00
0.40
0.0
3.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
36
306
1.18
0.40
2.5
2.3
124.89
130.31
g/l
0.54
28
250
8
61
1.31
0.39
1.0
1.0
20.00
19.22
mmol/l
—
8
54
0
19
0.00
0.39
0.0
3.3
—
—
—
0
0
48
547
0.87
0.38
2.1
1.9
—
—
—
0
0
38
326
1.17
0.38
1.7
3.8
1.95
3.59
ratio
0.69
24
180
48
420
1.15
0.38
1.1
1.2
0.82
0.90
g/l
1.72
48
420
50
439
1.14
0.38
2.0
1.9
0.80
2.10
ug/l
0.97
41
391
9
68
1.33
0.37
1.0
1.7
13.03
12.24
umol/l
—
9
61
41
355
1.16
0.37
1.7
4.1
27.02
45.71
mg/l
1.36
30
303
67
601
1.12
0.37
2.3
1.7
—
—
—
0
0
5
37
1.35
0.37
7.4
3.8
—
—
—
0
0
20
161
1.25
0.37
1.2
1.2
—
—
—
0
0
77
698
1.11
0.36
14.4
10.3
0.63
0.64
%
0.06
77
693
9
71
1.27
0.36
1.0
1.0
9.78
9.72
mu/l
—
9
57
965
9515
1.06
0.36
21.6
19.2
13.51
13.56
%
0.56
951
9392
31
263
1.18
0.36
8.1
4.8
—
—
—
0
0
15
117
1.29
0.35
1.1
1.1
21.88
14.04
u/ml
—
5
44
46
405
1.14
0.34
1.1
1.1
1.51
1.54
g/l
0.50
46
405
35
304
1.16
0.32
1.4
1.2
—
—
—
0
0
14
110
1.28
0.31
2.6
2.8
—
—
—
0
0
7
52
1.35
0.31
1.1
1.2
—
—
—
0
0
35
305
1.15
0.31
1.0
1.1
3.77
5.60
u/ml
0.43
21
180
7
56
1.25
0.29
60.0
32.8
6.79
7.11
ug/l
—
7
50
79
728
1.09
0.29
14.1
9.9
1.16
1.26
%
0.53
79
722
66
603
1.10
0.28
1.8
1.7
—
—
—
0
0
59
536
1.11
0.28
1.6
1.6
0.32
0.33
mg/l
0.03
21
250
20
167
1.20
0.28
1.6
1.6
—
—
—
0
0
20
167
1.20
0.28
1.6
1.6
—
—
—
0
0
20
167
1.20
0.28
1.6
1.6
—
—
—
0
0
20
167
1.20
0.28
1.6
1.6
—
—
—
0
0
24
280
0.85
0.28
6.2
4.0
3.86
3.92
mmol/l
0.22
24
275
66
605
1.10
0.27
2.4
1.7
—
—
—
0
0
39
347
1.13
0.27
1.1
1.2
0.12
3.29
u/ml
5.67
18
197
15
122
1.23
0.27
2.5
2.3
—
—
—
0
0
46
510
0.90
0.27
1.7
1.4
—
—
—
0
0
25
215
1.17
0.26
4.1
3.5
602.17
1470.19
u/ml
0.32
25
200
39
436
0.89
0.26
2.6
3.6
48.13
3447.78
u/ml
0.86
32
374
21
178
1.18
0.26
1.2
1.1
—
—
—
0
0
5
72
0.69
0.26
2.0
3.8
0.60
0.86
index
—
5
72
116
1092
1.07
0.26
2.1
2.1
0.00
0.02
estimate
0.78
27
226
5
75
0.67
0.26
1.4
1.4
4.06
6.73
u/l
—
5
63
22
188
1.17
0.25
1.2
1.2
3.18
6.27
u/ml
0.91
11
83
66
608
1.09
0.25
2.4
1.7
—
—
—
0
0
61
560
1.09
0.25
2.5
1.7
—
—
—
0
0
26
226
1.15
0.25
3.2
3.7
23.43
25.44
mg/l
0.17
16
152
348
3579
0.96
0.24
6.7
6.3
—
—
—
0
0
25
286
0.87
0.24
2.1
1.4
156.66
237.43
u/ml
2.22
16
157
47
427
1.10
0.24
4.1
4.2
400.26
319.66
mg/l
0.15
19
204
17
201
0.84
0.24
1.1
1.0
—
—
—
0
0
14
115
1.22
0.23
1.4
1.4
1165.00
1907.29
e6/l
—
7
73
27
237
1.14
0.23
1.4
1.7
—
—
—
0
0
5
38
1.32
0.23
1.0
2.0
41.52
41.03
g/l
—
5
38
13
106
1.23
0.23
1.2
1.1
—
—
—
0
0
24
274
0.87
0.22
1.5
1.4
118.25
216.37
pmol/l
0.59
24
266
5
40
1.25
0.22
1.0
1.1
—
38.22
—
0
22
21
242
0.87
0.22
2.2
2.4
93.40
137.38
ug/min
—
10
145
5
41
1.22
0.22
1.4
1.6
92.80
77.73
nmol/24h
—
5
41
13
107
1.22
0.21
1.2
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.21
—
0
5
33
296
1.12
0.21
1.0
1.1
1.73
2.03
u/ml
0.12
17
166
0
12
0.00
0.21
0.0
1.1
—
7.12
—
0
6
0
12
0.00
0.21
0.0
1.0
—
6.44
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
15
126
1.19
0.21
1.3
1.6
63.13
60.12
%
—
8
91
11
89
1.24
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
9.37
—
0
6
28
249
1.13
0.20
1.7
1.5
1.33
1.26
mm
0.33
23
181
118
1239
0.95
0.20
1.7
1.7
—
—
—
0
0
6
48
1.25
0.20
3.2
2.5
56.21
49.69
umol/l
—
6
42
13
108
1.21
0.20
1.1
1.2
—
—
—
0
0
13
108
1.21
0.20
1.2
1.1
—
—
—
0
0
207
2003
1.04
0.18
1.4
1.3
9.26
11.62
u/ml
0.23
77
737
5
70
0.71
0.16
2.2
3.0
17.00
16.52
%
—
5
70
29
263
1.10
0.16
1.8
1.6
—
—
—
0
0
48
447
1.08
0.16
1.8
1.6
13.23
12.28
u/ml
0.08
14
99
33
302
1.09
0.16
1.0
1.1
0.16
1.16
u/ml
2.09
15
147
42
452
0.93
0.15
1.1
1.1
—
—
—
0
0
210
2159
0.97
0.15
3.2
3.9
309.18
395.00
ng/l
0.30
149
1611
6
78
0.77
0.15
1.3
1.7
4.52
8.01
ug/l
—
6
67
116
1114
1.05
0.15
14.3
9.0
—
—
—
0
0
351
3577
0.97
0.15
4.5
4.1
6.00
8.94
mg/mmol
1.02
195
2242
115
1108
1.04
0.14
3.8
4.4
81.53
21.72
ug/l
0.38
94
909
27
247
1.09
0.13
2.1
1.6
135.90
139.06
au/ml
—
10
74
19
170
1.12
0.13
1.1
1.1
—
—
—
0
0
33
354
0.93
0.12
1.7
1.6
57.71
61.79
ug/l
0.27
27
306
150
1542
0.97
0.12
1.6
1.6
—
—
—
0
0
13
114
1.14
0.11
7.7
4.9
54.80
56.20
u/ml
—
7
35
28
259
1.08
0.11
1.8
1.5
—
—
—
0
0
40
376
1.07
0.11
1.1
1.1
0.69
0.69
ratio
—
5
41
28
261
1.07
0.10
1.6
1.8
1.20
0.84
nmol/l
0.53
22
219
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
31
330
0.94
0.09
1.2
1.2
—
—
—
0
0
20
184
1.09
0.09
1.6
1.8
—
—
—
0
0
34
321
1.06
0.09
8.7
10.2
—
—
—
0
0
22
204
1.08
0.08
1.1
1.2
—
—
—
0
0
6
58
1.03
0.08
1.8
1.8
—
—
—
0
0
6
58
1.03
0.08
1.2
1.4
6.35
6.09
mmol/l
—
6
58
12
133
0.90
0.07
2.3
2.3
—
—
—
0
0
8
75
1.07
0.07
2.5
1.4
74.25
78.08
umol/l
—
8
75
110
1123
0.98
0.06
2.6
2.4
40.65
39.26
u/l
0.07
89
935
11
99
1.11
0.06
1.3
1.1
—
—
—
0
0
33
344
0.96
0.05
1.1
1.2
—
—
—
0
0
69
674
1.02
0.05
14.4
10.0
23.79
24.21
mmol/l
0.55
69
662
160
1620
0.99
0.04
2.2
2.0
—
—
—
0
0
52
507
1.03
0.04
1.3
1.2
—
—
—
0
0
18
171
1.05
0.03
1.3
1.3
39.72
24.29
u/l
0.51
13
140
32
310
1.03
0.03
1.1
1.3
—
—
—
0
0
349
3505
0.99
0.02
3.4
3.5
32.08
47.31
mg/l
1.65
190
2245
394
3924
1.01
0.02
3.7
3.4
7.26
7.63
mmol/l
0.82
312
3363
22
212
1.04
0.02
3.7
3.4
0.65
0.84
nmol/l
1.93
13
178
46
452
1.02
0.01
1.7
1.3
189.33
249.61
miu/ml
0.76
24
225
278
2771
1.00
0.01
3.9
3.8
0.40
0.12
—
5
25
12
114
1.05
0.00
1.8
2.3
—
—
—
0
0
15
144
1.04
0.00
1.6
1.3
—
—
—
0
0
18
174
1.03
0.00
1.6
1.7
19.09
24.22
ng/l
0.79
18
174
27
264
1.02
0.00
2.1
1.6
—
—
—
0
0
56
566
0.99
0.00
5.9
3.6
1.02
1.02
ratio
0.02
49
525
11
111
0.99
0.00
1.1
1.2
—
—
—
0
0
17
174
0.98
0.00
1.5
1.2
—
—
—
0
0
20
195
1.03
0.00
1.5
1.4
—
—
—
0
0
32
322
0.99
0.00
2.3
3.3
0.88
1.93
index
1.13
17
168
17
166
1.02
0.00
1.6
1.7
—
—
—
0
0
17
166
1.02
0.00
1.8
1.3
47.73
11.23
nmol/l
0.34
17
160
18
178
1.01
0.00
1.3
1.2
—
—
—
0
0
65
651
1.00
0.00
1.6
1.6
886.84
957.97
mu/l
0.30
58
565
10
101
0.99
0.00
1.5
1.4
—
—
—
0
0
5
58
0.86
0.00
1.2
1.1
—
—
—
0
0
7
79
0.89
-0.00
1.3
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
4.34
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
68
0.88
-0.00
2.2
1.6
0.42
0.49
e9/l
—
6
68
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
0.03
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
74.99
—
0
7
0
7
0.00
-0.00
0.0
1.6
—
486.01
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.40
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
0.53
—
0
6
9
94
0.96
-0.00
1.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
166.00
—
0
7

Mortality – FinRegistry

Association

Association between endpoint H7_ANISOMETROPIA and mortality.

Females

Parameter HR [95% CI] p-value
H7_ANISOMETROPIA 0.844 [0.73, 0.97] 0.021
Birth year 0.992 [0.98, 1.0] 0.089

During the follow-up period (1.1.1998 — 31.12.2019), 417 out of 5603 females with H7_ANISOMETROPIA died.

Males

Parameter HR [95% CI] p-value
H7_ANISOMETROPIA 1.023 [0.85, 1.22] 0.807
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 288 out of 4430 males with H7_ANISOMETROPIA died.

Mortality risk

Mortality risk for people of age

years, who have H7_ANISOMETROPIA.

N-year risk Females Males
1 0.097% 0.203%
5 0.511% 1.122%
10 1.205% 2.815%
15 2.278% 5.208%
20 3.952% 8.999%

Relationships between endpoints

Index endpoint: H7_ANISOMETROPIA – Anisometropia and aniseikonia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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