No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
265 |
4. Check minimum number of eventsNone |
265 |
5. Include endpointsNone |
265 |
6. Filter based on genotype QC (FinnGen only) |
237 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Osteochondrosis of ankle, juvenile
based on the number of shared cases.
Similar with more cases:
- Juvenile osteochondrosis
- Chondropathies
- Other disorders of bone
- Osteopathies and chondropathies
- Diseases of the musculoskeletal system and connective tissue
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 237 | 173 | 64 |
| Unadjusted period prevalence (%) | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | 14.96 | 14.58 | 15.98 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 245
- Matched controls
- 2450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M92.6
ICD-10 Finland
Juvenile osteochondrosis of tarsus
+∞
289.5
217
*
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
67.2
101.8
57
11
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
54.4
35.0
41
9
7325X
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of foot
+∞
29.8
28
*
M79.6
ICD-10 Finland
Pain in limb
2.9
15.4
136
731
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
6.2
14.5
26
46
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
36.9
11.4
14
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
8.9
97
540
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
11.3
8.9
16
15
M25.5
ICD-10 Finland
Pain in joint
2.3
8.6
96
540
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
28.7
8.6
11
*
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
7.3
8.2
19
28
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.3
7.8
32
108
N02BE01
ATC
paracetamol; systemic, rectal
3.1
7.5
218
1776
M93.2
ICD-10 Finland
Osteochondritis dissecans
82.5
7.5
8
*
M85.8
ICD-10 Finland
Other specified disorders of bone density and structure
82.5
7.5
8
*
M01AH05
ATC
etoricoxib; oral
2.0
6.6
140
979
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
6.3
28
99
NHF30
NOMESCO Finland
Fixation of loose fragment from ankle joint
+∞
6.3
6
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.4
6.2
46
213
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
85
563
1.78
4.22
2.3
2.5
64.05
55.62
u/l
0.26
77
526
32
162
2.12
3.49
1.3
1.3
268.61
310.95
u/ml
0.08
32
152
48
302
1.73
2.75
1.5
1.5
455.10
24815251.60
pmol/l
0.50
42
270
84
615
1.56
2.64
3.1
3.4
0.00
0.00
estimate
0.50
31
239
5
7
7.26
2.56
1.0
6.1
21.78
12.63
ug/l
—
5
7
31
178
1.85
2.40
1.5
1.6
374.38
310.77
mu/l
0.21
26
158
5
10
5.08
2.08
2.0
1.3
232.60
190.10
u/l
—
5
10
61
445
1.49
1.89
1.5
2.1
0.94
0.94
mg/l
0.00
43
318
134
1145
1.38
1.68
3.1
3.5
0.00
0.00
estimate
-0.00
32
250
135
1155
1.38
1.68
3.3
3.5
0.00
0.00
estimate
-0.00
33
245
8
31
2.63
1.67
1.4
1.5
12.54
13.15
%
—
8
31
135
1161
1.36
1.60
3.4
3.6
0.00
0.00
estimate
-0.00
32
239
49
354
1.48
1.59
3.2
3.0
327.39
322.94
umol/l
0.12
44
325
226
2136
1.75
1.55
9.9
9.0
25.16
25.52
u/l
0.13
220
2080
12
58
2.12
1.52
1.8
3.8
54.40
45.07
%
0.87
12
58
6
21
2.90
1.51
1.0
1.0
—
—
—
0
0
196
1800
1.44
1.50
3.6
3.5
5.85
5.52
mmol/l
1.50
178
1657
123
1053
1.34
1.45
4.2
5.5
6.16
6.10
mmol/l
0.16
114
936
6
22
2.77
1.44
1.5
1.2
—
—
—
0
0
163
1457
1.35
1.43
4.3
3.7
8.35
8.27
mm/h
0.04
152
1367
155
1378
1.34
1.39
6.8
6.7
72.80
76.05
u/l
0.54
147
1300
0
37
0.00
1.35
0.0
1.1
—
17.25
—
0
15
43
314
1.45
1.33
3.6
2.5
1414.61
4133.41
u/l
0.84
12
130
103
873
1.31
1.26
2.9
3.2
0.00
0.01
estimate
0.80
27
209
8
36
2.26
1.25
1.0
1.1
—
—
—
0
0
99
836
1.31
1.24
2.2
1.9
—
—
—
0
0
8
40
2.03
1.13
1.1
1.2
—
—
—
0
0
179
1648
1.32
1.12
4.7
4.2
37.14
36.60
mmol/mol
0.35
172
1562
202
1894
1.38
1.11
3.8
4.1
—
—
—
0
0
32
233
1.43
1.02
1.2
1.3
233.08
131.33
u/ml
0.60
17
90
7
35
2.03
1.01
1.1
1.2
—
—
—
0
0
0
30
0.00
0.98
0.0
4.2
—
8.05
—
0
30
13
79
1.68
0.90
3.5
2.3
4.70
6.32
iu/l
—
7
35
19
129
1.51
0.86
1.2
1.3
—
—
—
0
0
10
57
1.79
0.85
1.1
1.4
—
—
—
0
0
16
105
1.56
0.84
1.1
1.2
0.98
2.73
u/ml
—
10
66
109
974
1.21
0.77
2.6
2.9
—
—
estimate
—
0
0
32
247
1.34
0.75
1.8
1.8
—
—
—
0
0
80
695
1.22
0.74
2.5
2.9
0.00
0.00
estimate
0.50
28
206
16
109
1.50
0.73
2.1
2.8
1.23
1.22
mmol/l
0.07
16
88
205
1961
1.28
0.70
6.5
5.2
1.77
1.76
mu/l
0.03
197
1854
23
304
0.73
0.70
2.7
3.0
8.16
184.43
ng/l
—
8
153
26
337
0.74
0.69
1.8
1.7
3.41
3.40
ratio
0.01
21
242
5
27
1.87
0.69
1.2
1.1
—
—
—
0
0
18
128
1.44
0.68
5.1
16.0
1.51
0.69
mmol/l
0.66
13
101
12
78
1.57
0.67
1.7
4.0
0.73
0.60
%
0.75
12
78
15
211
0.69
0.65
1.7
1.5
1.01
0.94
ratio
—
7
139
15
211
0.69
0.65
1.7
1.5
1.07
1.22
ratio
—
7
139
15
211
0.69
0.65
1.7
1.5
0.83
1.18
ratio
—
7
139
21
156
1.38
0.63
5.6
5.3
—
—
—
0
0
83
735
1.20
0.63
1.3
1.4
1.26
1.56
u/ml
0.19
30
190
5
30
1.68
0.62
1.4
1.2
—
—
—
0
0
181
1717
1.21
0.61
5.7
4.4
14.28
14.55
pmol/l
0.78
167
1571
84
746
1.19
0.61
2.6
2.4
—
—
—
0
0
15
206
0.71
0.58
1.7
1.5
—
—
—
0
0
65
567
1.20
0.58
3.7
2.7
16.32
21.80
ng/l
0.53
31
259
20
260
0.75
0.56
1.6
1.6
3.46
3.35
mmol/l
0.21
14
169
41
344
1.23
0.53
1.8
1.8
1.45
1.36
%
0.35
34
312
12
83
1.47
0.53
1.9
1.6
—
—
—
0
0
62
544
1.19
0.52
2.2
2.2
3.30
2.47
mg/l
1.76
53
469
10
67
1.51
0.50
1.0
1.2
—
—
—
0
0
10
67
1.51
0.50
1.0
1.2
—
—
—
0
0
25
200
1.28
0.49
1.4
1.7
—
—
—
0
0
22
275
0.78
0.47
1.3
1.5
—
—
—
0
0
14
103
1.38
0.46
1.6
2.8
3.97
6.47
umol/l
—
7
80
9
127
0.70
0.44
1.0
1.5
—
—
—
0
0
8
56
1.44
0.43
1.4
2.2
—
—
—
0
0
77
700
1.15
0.41
1.7
1.7
95.39
94.83
pmol/l
0.03
40
360
35
298
1.20
0.41
2.4
2.8
1.37
0.93
e6/l
0.27
19
147
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
21
256
0.80
0.38
4.7
4.2
0.82
0.81
mmol/l
0.15
21
244
189
1827
1.15
0.38
9.4
9.9
96.69
98.63
ml/min/173m2
0.68
169
1615
87
804
1.13
0.36
2.8
2.6
—
—
—
0
0
16
200
0.79
0.36
1.5
2.6
27.25
30.05
u/l
0.38
16
165
6
42
1.44
0.36
1.5
1.3
—
—
—
0
0
6
42
1.44
0.36
1.3
1.1
—
—
—
0
0
11
82
1.36
0.34
1.3
1.4
—
—
—
0
0
215
2102
1.19
0.34
13.1
11.2
18.50
19.84
mg/l
0.26
174
1653
51
458
1.14
0.33
2.0
2.3
—
—
—
0
0
10
74
1.37
0.33
1.6
2.1
—
—
—
0
0
45
402
1.15
0.31
1.4
1.3
11.91
20.33
iu/ml
—
10
102
191
1857
1.13
0.30
4.2
3.9
2.82
2.75
mmol/l
0.50
181
1766
113
1191
0.90
0.30
10.3
8.9
4.19
3.95
e9/l
0.58
107
1052
21
176
1.21
0.30
2.0
1.7
—
—
—
0
0
52
472
1.13
0.29
1.9
2.1
—
—
—
0
0
15
122
1.24
0.27
1.3
1.7
—
—
—
0
0
21
179
1.19
0.26
1.5
1.8
—
—
—
0
0
21
179
1.19
0.26
2.0
1.7
—
—
—
0
0
9
75
1.21
0.25
8.2
17.0
0.86
1.12
%
—
9
75
13
106
1.24
0.23
1.7
1.3
—
—
—
0
0
5
38
1.32
0.23
1.6
1.3
—
—
—
0
0
5
39
1.29
0.23
1.6
1.7
—
—
—
0
0
55
509
1.10
0.23
2.9
3.0
0.06
0.25
e6/l
3.87
40
370
41
374
1.12
0.22
1.3
1.3
1.54
4.96
u/ml
1.47
16
147
69
734
0.92
0.22
2.0
1.8
1.27
1.32
mmol/l
0.24
61
641
0
11
0.00
0.21
0.0
1.0
—
8.53
—
0
11
0
11
0.00
0.21
0.0
3.2
—
181.64
—
0
11
0
10
0.00
0.21
0.0
1.8
—
22.13
—
0
10
0
12
0.00
0.21
0.0
3.5
—
148.14
—
0
12
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
48.18
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
4.0
—
889.08
—
0
13
0
14
0.00
0.20
0.0
1.0
—
0.30
—
0
14
0
14
0.00
0.20
0.0
2.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
59
552
1.09
0.20
3.4
3.1
1.02
1.02
kg/l
0.15
29
339
17
146
1.18
0.20
1.8
1.6
0.41
0.21
mg/l
—
6
59
6
51
1.18
0.19
1.8
1.1
—
1.82
—
0
10
40
368
1.10
0.19
5.4
4.1
11.43
12.51
mg/mmol
0.05
28
249
23
205
1.13
0.17
1.8
1.6
1276.84
1099.53
nmol/l
0.29
18
155
52
487
1.09
0.17
1.6
1.5
—
—
—
0
0
5
67
0.74
0.17
1.4
1.3
—
10.06
—
0
10
6
79
0.75
0.15
1.3
1.5
—
—
—
0
0
20
179
1.13
0.14
6.5
10.3
106.90
105.05
mmol/l
1.63
20
179
10
118
0.84
0.14
5.0
11.8
24.67
25.06
mmol/l
—
10
118
18
160
1.13
0.14
3.7
2.7
—
—
—
0
0
187
1841
1.07
0.13
3.8
3.6
1.44
1.45
mmol/l
0.12
177
1751
174
1712
1.06
0.12
3.6
3.2
1.22
1.17
mmol/l
0.45
166
1622
80
773
1.05
0.11
4.5
8.2
1.22
1.21
mmol/l
0.19
66
677
6
54
1.11
0.09
1.2
1.4
—
—
—
0
0
6
57
1.05
0.08
1.2
2.1
—
—
—
0
0
6
58
1.04
0.08
1.0
1.1
—
—
—
0
0
5
62
0.80
0.08
2.6
2.8
86.40
100.82
ng/l
—
5
56
14
154
0.90
0.08
6.6
4.5
259.86
233.26
u/l
0.24
14
149
23
215
1.08
0.08
1.3
2.1
428.61
415.99
nmol/l
0.14
23
197
26
276
0.94
0.08
2.6
3.0
4.27
4.02
e6/l
0.04
11
127
8
78
1.03
0.07
1.0
2.1
52.38
37.19
u/l
—
8
73
7
85
0.82
0.07
1.3
1.2
—
—
—
0
0
152
1500
1.04
0.07
3.3
3.1
34.03
32.19
u/l
0.22
147
1447
187
1852
1.04
0.07
4.1
3.7
4.65
4.61
mmol/l
0.26
179
1765
9
105
0.85
0.06
1.6
1.5
—
—
—
0
0
29
303
0.95
0.05
2.9
3.2
521.96
776.44
ng/l
0.58
24
236
17
159
1.07
0.05
1.5
1.5
74.43
57.54
ug/l
0.56
17
159
45
464
0.96
0.05
2.2
2.1
147.20
289.92
u/l
0.51
45
448
56
549
1.03
0.03
2.6
2.2
—
—
—
0
0
24
231
1.04
0.03
1.7
3.1
30.37
29.39
s
0.33
24
226
19
182
1.05
0.02
1.2
1.3
202.75
250.60
miu/ml
—
8
88
21
217
0.96
0.01
1.1
1.3
—
—
—
0
0
11
116
0.95
0.01
2.5
4.9
50.49
66.24
ng/l
0.91
11
105
13
136
0.95
0.00
1.5
2.1
—
—
—
0
0
10
101
0.99
0.00
1.1
1.0
1.53
1.53
g/l
—
10
101
10
103
0.97
0.00
1.1
1.1
0.87
0.87
g/l
—
10
103
10
97
1.03
0.00
1.5
1.3
—
—
—
0
0
19
194
0.98
0.00
1.1
1.0
—
—
—
0
0
6
59
1.02
0.00
3.7
2.0
27.62
24.01
mmol/l
—
6
59
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
11.33
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
71
0.99
-0.00
10.1
17.8
0.64
0.64
%
—
7
71
7
69
1.01
-0.00
1.9
2.0
447.71
292.39
ug/l
—
7
63
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
1360.40
—
0
9
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
77
0.91
-0.00
1.6
3.9
94.57
94.86
%
—
7
77
0
8
0.00
-0.00
0.0
1.8
—
115.57
—
0
8
0
6
0.00
-0.00
0.0
3.5
—
4.76
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
99
0.91
-0.00
1.2
1.4
4.69
3.46
ug/l
—
9
91
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: M13_OSTEOCHONDROSIS_OF_ANKLE_JUVENILE – Osteochondrosis of ankle, juvenile
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).