Congenital malformations of breast, including avohilmo

Q17_CONGEN_MALFO_BREAST_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 Q83
  • Hospital discharge: ICD-10 Q83
  • Cause of death: ICD-10 Q83

3 out of 7 registries used, show all original rules.

800

4. Check minimum number of events

None

800

5. Include endpoints

None

800

6. Filter based on genotype QC (FinnGen only)

725

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13
Parent code in ICD-10
Q8
Name in latin
Malformationes congenitae mammae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 725 714 11
Unadjusted period prevalence (%) 0.25 0.25 0.01
Median age at first event (years) 33.40 33.23 44.00

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
760
Matched controls
7600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q83.8
ICD-10 Finland
Other congenital malformations of breast
+∞
307.7
377
*
Q83.1
ICD-10 Finland
Accessory breast
+∞
298.2
266
*
HAD40
NOMESCO Finland
Mastopexy
80.7
160.7
86
12
HAD99
NOMESCO Finland
Other plastic operation on breast
40.4
134.8
83
23
HAD10
NOMESCO Finland
Augmentation of breast using prosthesis
177.1
128.9
132
9
ZZF00
NOMESCO Finland
Graft of adipose tissue
33.0
122.6
80
27
HAC30
NOMESCO Finland
Excision of supernumerary mammary gland or mamilla
1108.4
101.6
97
*
Q83.9
ICD-10 Finland
Congenital malformation of breast, unspecified
+∞
88.3
83
*
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
43.4
74.7
45
11
HAE99
NOMESCO Finland
Other reconstruction of breast
23.2
70.7
52
24
Q83.3
ICD-10 Finland
Accessory nipple
+∞
57.0
54
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
4.8
53.3
139
342
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
6.0
51.7
98
182
N64.8
ICD-10 Finland
Other specified disorders of breast
14.6
42.8
39
28
N64.9
ICD-10 Finland
Disorder of breast, unspecified
8.9
33.8
43
51
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.5
33.7
88
214
ZXA10
NOMESCO Finland
Bilateral
3.1
32.9
168
641
N62
ICD-10 Finland
Hypertrophy of breast
4.5
31.5
83
203
HAD00
NOMESCO Finland
Augmentation mammoplasty
86.2
30.0
33
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
28.6
287
1526
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
104.0
27.8
30
*
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
5.4
25.8
53
105
HA1AA
NOMESCO Finland
X-ray mammography
3.5
25.2
95
299
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
24.2
203
984
QBJ00
NOMESCO Finland
Liposuction in trunk
23.0
21.8
31
14
N64.2
ICD-10 Finland
Atrophy of breast
49.5
20.3
24
5
WX402
NOMESCO Finland
General anaesthesia
2.2
19.3
215
1161
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
18.7
281
1698
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
53.9
18.0
21
*
Q83
ICD-10 Finland
Congenital malformations of breast
+∞
17.8
17
*
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
17.9
17.0
26
15
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
17.0
199
1089
N64.5
ICD-10 Finland
Other signs and symptoms in breast
3.7
16.3
52
146
Q83.0
ICD-10 Finland
Congenital absence of breast with absent nipple
+∞
15.7
15
*
M03AX01
ATC
botulinum toxin; parenteral
4.3
14.7
38
91
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
5.4
14.3
28
53
ZXA05
NOMESCO Finland
Left side
2.2
14.1
135
679
6114A
ICD-9 Finland
Other disorders of breast, Atrophy of breast
50.9
12.9
15
*
N63
ICD-10 Finland
Unspecified lump in breast
2.3
12.2
96
443
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.3
11.7
44
138
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
11.6
354
2568
9729
FHL
Other measure in this category
28.5
10.8
14
5
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
9.7
10.3
20
21
N02BE01
ATC
paracetamol; systemic, rectal
2.2
10.1
677
6012
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
5.2
9.9
20
39
ZXE00
NOMESCO Finland
One hour or less
1.6
9.7
304
2192
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
17.8
9.4
14
8
HAB99
NOMESCO Finland
Other partial excision of mammary gland
4.1
9.3
25
62
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
9.2
354
2674
P01AB01
ATC
metronidazole; oral, rectal
1.6
9.0
337
2528
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
12.7
8.9
15
12
ZXA00
NOMESCO Finland
Right side
1.9
8.5
129
756
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
4.4
8.4
21
49
J01DB01
ATC
cefalexin; oral
1.8
8.4
643
5694
J02AC01
ATC
fluconazole; systemic
1.6
8.2
383
2998
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
8.2
327
2474
HA1AE, ,
SPAT
2.3
8.2
60
269
X21
ICPC
Breast sympt/compl female other
2.9
8.1
38
136
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.6
8.1
46
183
R4110
NOMESCO Finland
Physiotherapy
1.7
8.0
176
1148
N64.4
ICD-10 Finland
Mastodynia
2.4
8.0
54
233
J01AA02
ATC
doxycycline; systemic
1.6
7.6
526
4463
S59
ICPC
Skin, Other therap proced/minor surg NEC
3.6
7.6
25
72
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.9
7.5
92
503
C05AA08
ATC
fluocortolone; rectal, topical
2.0
7.4
78
405
WX702
NOMESCO Finland
Supraglottic ventilation device
2.5
7.3
47
199
Z2221
NOMESCO Finland
Medical doctor
1.6
7.2
218
1537
QBJ99
NOMESCO Finland
Other aesthetic correction of skin of trunk
30.3
7.2
9
*
Z41.1
ICD-10 Finland
Other plastic surgery for unacceptable cosmetic appearance
8.9
7.1
14
16
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
7.1
278
2078
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
7.1
295
2234
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
5.7
6.8
18
32
N05BA04
ATC
oxazepam; oral
1.6
6.8
204
1435
C07AA05
ATC
propranolol; systemic
1.6
6.6
186
1287
F41.1
ICD-10 Finland
Generalized anxiety disorder
1.9
6.4
88
499
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.4
215
1547
F51.0
ICD-10 Finland
Nonorganic insomnia
1.6
6.4
192
1347
HAD41
NOMESCO Finland
Transposition of areola
+∞
6.3
6
*
Q79.8
ICD-10 Finland
Other congenital malformations of musculoskeletal system
+∞
6.3
6
*
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
3.5
6.2
21
62
J01EA01
ATC
trimethoprim; systemic
1.5
6.2
217
1575
X22
ICPC
Concern breast appearance fema
12.6
6.1
10
8
S18
ICPC
Laceration/cut
1.5
6.1
290
2240
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.3
6.0
22
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
158
844
2.10
14.14
1.3
1.2
—
—
—
0
0
223
1457
1.75
10.46
2.9
3.2
100.40
97.38
%
1.31
217
1414
366
2792
1.60
9.12
2.2
1.9
—
—
—
0
0
544
4617
1.63
8.22
6.7
6.5
70.48
71.99
u/l
0.55
519
4390
302
2276
1.54
7.50
3.7
4.2
37.78
37.40
g/l
0.67
280
2157
417
3423
1.48
6.58
2.8
2.7
—
—
estimate
—
0
0
369
2994
1.45
5.95
4.8
4.9
9.40
9.46
umol/l
0.05
345
2818
288
2232
1.47
5.89
2.0
1.9
—
—
—
0
0
16
41
3.96
5.74
1.1
1.0
—
—
—
0
0
664
6105
1.69
5.51
15.6
13.3
13.21
13.26
%
0.57
659
6033
175
1243
1.53
5.42
2.5
2.4
96.13
80.39
ug/g
0.43
138
968
240
1823
1.46
5.34
2.6
2.3
58.41
58.50
u/l
0.01
219
1699
389
3243
1.41
5.12
6.0
5.4
55.23
56.44
%
1.53
366
3117
393
3299
1.40
4.88
6.1
5.5
30.93
29.84
%
1.55
370
3153
317
2566
1.40
4.88
5.4
5.4
1.22
1.22
mmol/l
0.31
283
2204
558
4982
1.45
4.83
3.1
2.9
32.04
30.50
u/l
0.32
535
4809
126
863
1.55
4.56
1.5
1.4
19.86
23.07
iu/l
0.59
104
742
376
3157
1.38
4.54
6.4
5.6
0.69
0.68
%
0.14
347
2969
46
237
2.00
4.50
1.3
1.2
—
—
—
0
0
370
3103
1.37
4.48
2.7
2.5
73.90
73.78
nmol/l
0.03
344
2925
375
3157
1.37
4.41
6.4
5.6
8.02
8.10
%
0.25
348
2987
638
5884
1.53
4.38
5.0
4.9
14.18
14.25
pmol/l
0.33
605
5544
374
3155
1.37
4.31
6.3
5.6
2.73
2.66
%
0.21
346
2976
681
6395
1.62
4.07
11.2
10.2
3.87
3.88
mmol/l
0.59
668
6228
258
2067
1.38
4.05
2.2
2.2
—
—
—
0
0
363
3070
1.35
4.01
2.9
3.0
6.22
6.25
ph
0.20
196
1760
440
3834
1.35
3.98
8.0
8.1
3.80
3.95
e9/l
0.88
383
3375
679
6384
1.60
3.89
11.1
10.2
139.48
139.52
mmol/l
0.22
667
6235
710
6763
1.76
3.71
12.5
10.8
18.78
18.07
mg/l
0.24
575
5411
273
2235
1.35
3.66
4.9
4.8
1.22
1.22
mmol/l
0.65
254
2072
53
308
1.77
3.64
1.7
1.4
0.81
0.40
nmol/l
0.44
40
264
397
3445
1.32
3.51
6.1
5.7
0.04
0.04
e9/l
0.10
346
3045
396
3440
1.32
3.45
6.1
5.6
0.52
0.52
e9/l
0.09
345
3046
410
3587
1.31
3.35
6.3
5.9
0.18
0.17
e9/l
0.24
364
3216
432
3811
1.31
3.30
3.5
3.3
0.01
0.00
estimate
0.42
90
848
201
1600
1.35
3.18
2.9
2.5
0.19
0.33
e6/l
0.66
145
1117
406
3564
1.30
3.17
6.1
5.6
2.02
2.01
e9/l
0.13
363
3228
501
4528
1.31
3.12
3.5
3.3
61.78
57.31
ug/l
0.69
477
4322
22
99
2.26
3.08
2.7
2.2
8.45
6.70
pmol/l
0.45
22
99
288
2423
1.30
3.07
1.8
1.8
100.13
97.62
pmol/l
0.50
146
1364
193
1535
1.34
3.06
3.7
3.4
7.39
7.40
ph
0.66
130
1068
270
2253
1.31
3.06
1.4
1.4
0.91
1.97
u/ml
1.38
76
633
61
388
1.62
3.05
1.4
1.4
9.94
10.33
u/l
0.09
44
319
93
652
1.49
3.03
1.5
1.7
—
—
—
0
0
755
7424
3.58
3.00
20.0
17.2
4.44
4.46
e12/l
1.13
744
7317
5
180
0.27
2.99
3.6
6.8
—
—
—
0
0
755
7420
3.66
2.99
20.1
17.2
268.13
267.97
e9/l
0.02
745
7325
92
650
1.47
2.89
1.5
1.7
—
—
—
0
0
112
822
1.43
2.88
1.2
1.1
—
—
—
0
0
517
4716
1.30
2.87
4.8
4.1
45.00
1612.51
e6/l
—
6
53
755
7425
3.56
2.85
20.0
17.2
6.68
6.76
e9/l
0.60
744
7312
719
6927
1.70
2.84
13.3
11.9
65.08
65.40
umol/l
0.25
710
6851
433
3865
1.28
2.83
3.7
3.4
0.00
0.01
estimate
1.08
88
828
92
654
1.46
2.80
1.5
1.7
—
—
—
0
0
86
606
1.47
2.74
2.6
2.0
6.29
6.29
ph
0.00
59
387
92
658
1.45
2.72
1.5
1.7
—
—
—
0
0
115
860
1.40
2.66
2.8
2.3
2.18
5.04
e6/l
4.89
49
367
429
3850
1.26
2.58
3.6
3.4
0.00
7.58
estimate
1.33
90
849
85
606
1.45
2.56
1.5
1.7
—
—
—
0
0
43
263
1.67
2.53
2.1
2.0
20.64
20.08
s
0.59
36
223
102
756
1.40
2.49
2.2
2.3
24.82
23.78
%
0.32
96
694
49
313
1.60
2.45
1.7
1.6
11.74
8.69
u/ml
0.25
14
79
20
97
2.09
2.39
3.6
2.3
—
—
—
0
0
115
879
1.36
2.34
3.2
2.8
62.11
300.09
ng/l
1.26
55
422
75
532
1.45
2.34
1.5
1.7
—
—
—
0
0
236
1993
1.27
2.33
5.7
6.2
1.05
1.06
inr
0.35
202
1665
52
342
1.56
2.31
3.4
3.8
11.07
6.52
ug/l
0.31
36
243
58
391
1.52
2.31
1.1
1.1
—
—
—
0
0
222
1865
1.27
2.28
3.1
2.7
401.88
66.08
e6/l
0.43
166
1376
269
2314
1.25
2.26
2.8
2.9
32.21
26.53
u/l
0.59
255
2201
718
6955
1.59
2.24
10.1
9.1
23.87
23.06
u/l
0.80
700
6803
191
1579
1.28
2.23
1.9
1.8
0.86
0.82
mg/l
0.10
151
1184
225
1900
1.26
2.21
1.5
1.4
2.04
2.04
g/l
0.02
144
1241
156
1258
1.30
2.21
2.4
2.4
9.93
10.59
e6/l
0.12
144
1134
76
550
1.42
2.14
1.3
1.3
—
—
—
0
0
602
5686
1.28
2.07
4.4
4.4
35.90
36.63
mmol/mol
1.84
576
5456
146
1177
1.30
2.07
3.8
3.2
—
—
—
0
0
107
827
1.34
2.04
2.4
2.8
3.76
4.86
e9/l
1.72
97
758
56
387
1.48
2.01
1.2
1.2
—
—
—
0
0
102
785
1.35
2.00
1.9
1.8
—
—
—
0
0
36
225
1.63
2.00
1.3
1.3
—
—
—
0
0
40
257
1.59
1.99
1.0
1.1
0.72
5.57
eliau/ml
—
10
49
25
141
1.80
1.99
1.0
1.1
—
—
—
0
0
136
1093
1.30
1.97
2.6
2.4
535.92
519.65
mosm/kgh2o
0.21
122
967
280
2451
1.23
1.95
3.8
3.2
75.08
55.27
e6/l
0.31
180
1523
95
729
1.35
1.91
1.8
2.1
380.76
385.85
nmol/l
0.09
86
681
318
2827
1.21
1.88
1.9
1.9
—
—
—
0
0
15
72
2.11
1.87
1.3
1.3
—
—
—
0
0
64
462
1.42
1.85
1.2
1.2
—
—
—
0
0
228
1963
1.23
1.84
2.7
2.8
2.36
2.35
mmol/l
0.84
217
1839
197
1673
1.24
1.81
2.9
3.3
1.02
2.86
kg/l
0.80
119
1093
680
6562
1.34
1.74
6.1
5.7
1.61
1.72
mu/l
1.22
660
6311
109
867
1.30
1.72
2.2
2.2
2.48
2.49
g/l
0.08
99
790
175
1478
1.24
1.68
2.4
2.5
—
—
—
0
0
78
593
1.35
1.68
2.1
2.2
33.42
35.59
u/l
0.16
66
493
333
3000
1.20
1.66
2.4
2.3
—
—
—
0
0
8
31
2.60
1.66
1.1
1.5
199.63
164.70
mmol/24h
—
8
31
16
83
1.95
1.65
1.4
1.4
—
—
—
0
0
725
7080
1.52
1.65
11.6
10.0
—
—
—
0
0
86
669
1.32
1.60
1.4
1.3
—
—
—
0
0
340
3077
1.19
1.59
9.1
8.7
0.00
0.00
e9/l
1.02
271
2534
189
1619
1.22
1.59
1.6
1.6
—
—
—
0
0
94
742
1.30
1.58
1.6
1.5
—
—
—
0
0
629
6031
1.25
1.53
3.8
3.7
5.52
5.53
mmol/l
0.06
589
5708
23
138
1.69
1.53
2.0
2.8
0.75
1.63
index
0.78
12
67
262
2324
1.19
1.53
3.0
2.7
0.02
0.02
estimate
0.05
83
720
84
658
1.31
1.50
3.6
3.2
—
—
—
0
0
12
58
2.09
1.49
1.1
1.0
—
—
—
0
0
38
260
1.49
1.49
1.1
1.1
1.09
0.74
u/ml
0.32
16
106
116
950
1.26
1.47
2.2
2.2
15.68
14.60
umol/l
0.75
109
875
21
125
1.70
1.45
1.1
1.2
—
—
—
0
0
12
59
2.05
1.44
1.2
1.1
127.67
115.58
pmol/l
0.46
12
59
25
157
1.61
1.42
2.1
2.1
1.26
1.27
g/l
0.02
20
139
77
604
1.31
1.37
3.0
3.7
4.48
4.65
pmol/l
1.05
72
545
93
750
1.27
1.35
1.1
1.2
—
—
—
0
0
71
553
1.31
1.34
3.6
5.3
1.02
1.06
mmol/l
0.62
66
513
47
343
1.39
1.33
2.2
3.8
77.60
69.45
ng/l
0.34
42
313
207
1820
1.19
1.31
2.3
2.1
2.30
2.52
mg/l
1.13
173
1578
103
844
1.25
1.31
1.6
1.5
—
—
—
0
0
375
3462
1.16
1.30
4.0
4.0
5.90
6.16
mmol/l
2.37
344
3101
79
629
1.29
1.27
1.3
1.3
143.63
331.43
u/ml
0.68
73
590
44
321
1.39
1.26
2.3
2.1
7.03
4.67
umol/l
0.48
36
238
16
92
1.76
1.25
1.1
1.0
0.20
2.36
u/ml
—
5
35
116
969
1.23
1.25
1.9
2.1
2.42
2.41
mmol/l
0.54
107
863
17
100
1.72
1.24
1.0
1.1
—
—
—
0
0
189
1658
1.19
1.23
1.9
1.9
—
—
—
0
0
15
87
1.74
1.15
3.5
2.3
3.29
2.42
mmol/l
—
10
55
0
35
0.00
1.15
0.0
1.7
—
—
—
0
0
54
415
1.32
1.14
1.4
1.4
—
—
—
0
0
39
286
1.38
1.11
1.9
2.3
2.70
3.73
iu/l
0.78
19
132
5
21
2.39
1.09
1.8
1.9
—
—
—
0
0
191
1696
1.17
1.07
2.4
3.1
7.38
7.97
mmol/l
0.99
175
1485
18
113
1.61
1.06
1.9
1.6
5742.25
10477.76
e6/l
0.42
12
84
90
747
1.23
1.05
2.4
2.0
—
—
—
0
0
166
1461
1.17
1.04
1.4
1.3
2.06
9.91
u/ml
4.29
66
609
41
307
1.35
1.04
1.2
1.2
2.36
3.27
u/ml
0.33
22
160
25
171
1.48
1.03
3.6
3.3
57.54
58.26
%
0.15
25
171
173
1529
1.17
1.03
1.5
1.5
20.68
20.46
nmol/l
0.08
149
1367
19
122
1.57
1.03
3.1
3.1
21.94
25.22
mg/l
0.20
11
80
211
1896
1.16
1.01
5.9
5.3
—
—
—
0
0
44
336
1.33
0.99
7.1
6.9
—
—
—
0
0
207
1863
1.15
0.97
3.5
3.9
—
—
—
0
0
55
435
1.28
0.97
2.6
3.2
7.38
7.33
ph
3.19
41
308
7
36
1.95
0.97
3.3
2.6
—
—
—
0
0
22
149
1.49
0.96
1.3
1.4
25.10
5.66
u/ml
—
10
64
23
158
1.47
0.94
1.0
1.1
1.34
2.56
eliau/ml
1.00
12
87
317
2942
1.13
0.94
3.2
3.1
0.00
0.03
estimate
2.36
79
708
7
37
1.90
0.94
2.7
1.3
62114.00
13667.00
e6/l
—
7
25
21
142
1.49
0.93
2.7
2.7
—
20.94
—
0
8
60
484
1.26
0.92
1.5
2.1
—
—
—
0
0
196
1765
1.15
0.91
2.4
2.7
13.18
79.64
ng/l
0.65
79
739
32
236
1.37
0.91
2.1
2.1
—
—
—
0
0
103
881
1.20
0.91
1.2
1.3
139.39
150.16
u/ml
0.10
39
362
36
271
1.34
0.90
1.1
1.1
2.61
5.31
u/ml
1.19
19
146
79
659
1.22
0.90
1.8
1.7
—
—
—
0
0
6
29
2.08
0.89
2.0
2.8
264.50
161.07
e6/l
—
6
29
19
127
1.51
0.89
1.4
1.3
—
—
—
0
0
271
2498
1.13
0.89
1.8
1.8
1.26
1.28
mmol/l
0.17
239
2231
12
71
1.70
0.89
1.4
1.4
331.67
446.98
pmol/l
0.59
12
63
82
688
1.22
0.89
2.1
2.2
5.97
5.07
umol/l
0.24
64
564
8
42
1.91
0.88
1.8
1.9
43.11
47.68
%
—
8
42
15
95
1.59
0.88
1.2
1.0
0.53
1.39
u/ml
—
5
27
8
43
1.87
0.87
1.1
1.1
—
—
—
0
0
6
30
2.01
0.87
1.0
1.1
6.00
6.26
nmol/l
—
6
30
25
179
1.41
0.85
1.1
1.3
288.07
216.34
u/ml
0.81
15
113
6
32
1.88
0.82
1.2
1.1
—
—
—
0
0
175
1579
1.14
0.80
1.4
1.3
15.64
23.16
iu/ml
1.16
56
451
148
1321
1.15
0.79
1.7
1.6
—
—
—
0
0
6
34
1.77
0.76
3.5
2.0
—
—
—
0
0
10
59
1.70
0.76
1.3
1.1
—
—
—
0
0
11
67
1.65
0.75
1.0
1.1
1.04
1.05
ratio
0.26
11
55
64
534
1.22
0.75
2.5
2.4
13.95
17.60
au/ml
0.41
14
71
65
544
1.21
0.74
1.3
1.2
—
—
—
0
0
7
38
1.85
0.73
1.9
3.0
—
—
—
0
0
7
38
1.85
0.73
3.3
2.0
—
—
—
0
0
115
1014
1.16
0.73
1.3
1.3
—
—
—
0
0
33
256
1.30
0.71
2.0
2.9
7.42
7.41
ph
0.12
28
215
5
26
1.93
0.70
1.0
1.1
—
—
—
0
0
25
187
1.35
0.69
1.4
1.3
—
—
—
0
0
12
77
1.57
0.69
1.0
1.2
—
—
—
0
0
42
340
1.25
0.66
6.1
7.4
97.17
96.05
%
0.91
42
333
13
86
1.52
0.66
1.7
1.7
—
—
—
0
0
248
2313
1.11
0.65
2.0
1.9
—
—
—
0
0
8
128
0.62
0.64
1.6
1.8
432.88
140.08
ug/l
—
8
113
17
121
1.41
0.62
1.5
2.1
10.04
10.15
g/l
0.04
17
115
10
63
1.60
0.62
1.0
1.1
—
—
—
0
0
88
772
1.16
0.61
1.4
1.3
—
—
—
0
0
26
201
1.30
0.59
1.0
1.0
0.04
0.21
u/ml
—
8
57
36
291
1.25
0.59
1.7
1.9
—
—
—
0
0
16
219
0.72
0.58
1.8
2.1
12.87
4.79
ug/l
0.40
16
191
10
65
1.55
0.55
2.3
3.8
—
—
—
0
0
22
168
1.32
0.55
1.2
1.3
—
—
—
0
0
66
572
1.17
0.55
1.3
1.3
212.67
245.16
miu/ml
0.38
33
306
266
2509
1.09
0.54
1.9
1.8
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
18
135
1.34
0.51
4.1
3.4
3.89
4.25
e9/l
0.37
18
135
32
261
1.24
0.50
1.5
1.4
—
—
—
0
0
6
41
1.47
0.50
1.2
1.0
—
—
—
0
0
80
710
1.14
0.50
1.7
1.6
1364.90
1148.06
nmol/l
0.50
71
545
17
127
1.35
0.50
1.1
1.1
—
—
—
0
0
7
45
1.56
0.49
1.0
1.0
—
—
—
0
0
126
1153
1.11
0.48
1.5
1.4
702.61
558.67
titre
0.26
23
241
7
49
1.43
0.46
1.3
1.4
94.81
92.29
%
—
7
49
5
84
0.59
0.45
1.6
1.1
—
—
—
0
0
71
630
1.14
0.45
1.5
1.5
1.31
1.27
mm
0.33
51
467
35
293
1.20
0.44
1.5
1.7
—
—
—
0
0
12
86
1.40
0.44
1.6
2.1
—
—
—
0
0
72
641
1.14
0.44
1.5
1.5
—
—
—
0
0
32
266
1.21
0.44
1.2
1.1
0.84
2.06
u/ml
1.38
18
134
19
148
1.29
0.44
5.1
2.9
1.35
1.23
mg/l
0.22
19
132
6
92
0.65
0.42
2.5
6.7
309.17
377.25
umol/l
—
6
81
143
1329
1.09
0.41
2.0
2.2
295.81
295.95
umol/l
0.01
129
1219
73
655
1.13
0.40
1.6
1.6
—
—
—
0
0
8
60
1.34
0.40
1.5
1.6
7.41
9.85
umol/l
—
8
55
74
666
1.12
0.39
1.5
1.7
248.22
303.27
mu/l
1.97
69
589
8
61
1.31
0.39
1.8
1.4
—
—
—
0
0
5
35
1.43
0.39
1.8
1.1
12.00
12.85
pmol/l
—
5
30
14
106
1.33
0.39
1.1
1.0
—
—
—
0
0
14
180
0.77
0.37
1.1
1.3
3.51
3.60
mmol/l
0.24
14
170
5
37
1.35
0.37
1.8
2.7
—
—
—
0
0
25
209
1.20
0.34
1.5
2.1
—
—
—
0
0
6
45
1.34
0.34
1.5
1.2
33.83
32.16
pg
—
6
45
600
5907
1.07
0.33
3.4
3.3
1.12
1.15
mmol/l
0.67
575
5641
26
219
1.19
0.33
1.1
1.1
0.70
6.49
u/ml
3.99
13
99
6
46
1.31
0.33
1.2
1.3
62.50
67.59
umol/l
—
6
46
33
285
1.17
0.32
1.8
1.9
—
—
—
0
0
35
401
0.87
0.32
1.1
1.1
1.62
1.58
g/l
0.53
35
401
69
628
1.11
0.32
2.6
1.9
0.17
0.03
estimate
0.36
12
159
11
83
1.33
0.32
1.2
1.7
31.08
22.87
ng/l
0.27
11
83
13
101
1.29
0.32
3.2
1.9
5.91
5.23
mmol/24h
0.35
13
90
214
2047
1.06
0.30
3.6
3.4
0.00
0.00
estimate
1.08
87
825
7
54
1.30
0.30
1.0
1.1
1195.71
1622.35
miu/ml
—
7
54
24
203
1.19
0.30
1.1
1.3
—
—
—
0
0
36
408
0.88
0.29
1.2
1.2
0.81
0.85
g/l
0.57
36
408
43
383
1.13
0.29
3.2
2.9
1.23
1.22
mmol/l
0.41
37
322
20
167
1.20
0.28
1.1
1.5
—
—
—
0
0
33
290
1.14
0.27
3.3
2.2
61.77
73.71
e9/l
1.79
22
197
28
243
1.16
0.27
1.2
1.1
—
—
—
0
0
47
425
1.11
0.26
1.1
1.1
—
—
—
0
0
19
160
1.19
0.25
1.2
1.3
133.40
170.87
au/ml
—
5
43
91
852
1.08
0.25
1.6
1.5
62.77
60.38
ug/l
0.15
73
731
27
236
1.15
0.24
1.1
1.1
0.60
5.39
u/ml
3.30
14
117
24
208
1.16
0.24
6.8
7.6
16.07
15.88
%
0.13
24
201
640
6335
1.06
0.24
4.0
3.9
4.78
4.75
mmol/l
0.42
623
6096
638
6315
1.06
0.23
3.9
3.8
1.56
1.53
mmol/l
1.15
617
6050
42
380
1.11
0.23
2.5
3.0
1.66
1.71
mmol/l
0.02
37
316
644
6377
1.06
0.23
4.3
4.1
2.84
2.82
mmol/l
0.33
621
6117
14
168
0.83
0.23
2.4
2.9
25.23
24.84
mmol/l
0.18
14
161
21
181
1.16
0.22
1.2
1.4
357.33
326.25
ug/g
—
9
98
21
182
1.16
0.21
3.1
4.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
15
177
0.84
0.21
1.5
3.1
208.60
334.17
mg/l
—
5
72
102
967
1.06
0.21
1.5
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
1.35
—
0
8
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
13
108
1.21
0.20
2.4
2.3
—
—
—
0
0
76
715
1.07
0.19
1.4
1.3
—
—
—
0
0
17
146
1.17
0.19
1.1
1.2
—
—
—
0
0
6
52
1.16
0.19
1.0
1.1
—
—
—
0
0
6
53
1.13
0.18
1.2
1.2
5.08
5.84
ug/l
—
6
47
42
386
1.09
0.18
2.5
3.0
5.99
5.76
kpa
0.56
42
376
134
1287
1.05
0.18
3.2
4.1
5.48
9.02
mg/mmol
0.71
77
804
7
59
1.19
0.18
1.1
1.7
—
—
—
0
0
11
91
1.21
0.17
1.5
1.3
—
—
—
0
0
85
895
0.94
0.17
1.6
1.6
3.41
3.35
mmol/l
0.17
53
590
5
69
0.72
0.17
3.8
2.1
10.84
10.37
u/ml
—
5
69
155
1498
1.04
0.16
1.5
1.6
1200.80
993.92
mu/l
1.66
130
1293
118
1134
1.05
0.16
1.6
1.6
45714714.52
40980820.23
pmol/l
0.03
105
1020
40
370
1.09
0.16
7.6
5.6
1.18
1.16
mmol/l
0.08
40
361
8
72
1.11
0.16
1.1
1.2
—
—
—
0
0
24
216
1.11
0.15
1.3
1.1
—
—
—
0
0
24
216
1.11
0.15
1.3
1.1
—
—
—
0
0
16
182
0.88
0.15
1.1
1.6
1.64
1520.87
e6/l
0.53
11
140
35
324
1.08
0.14
2.5
1.9
0.00
0.01
estimate
0.50
11
131
109
1050
1.04
0.14
2.3
2.3
5115.67
7129.32
u/l
0.32
48
455
42
393
1.07
0.13
7.7
7.0
1.08
0.97
mmol/l
0.06
34
319
42
393
1.07
0.13
2.5
3.0
7.38
7.38
ph
0.31
23
227
16
180
0.89
0.13
1.1
1.5
10.27
27.81
e6/l
0.59
11
133
10
116
0.86
0.12
2.6
2.2
134.90
131.93
g/l
—
10
97
49
517
0.94
0.12
5.2
5.6
106.00
104.93
mmol/l
1.45
49
517
313
3085
1.02
0.11
2.5
2.4
—
—
—
0
0
115
1183
0.97
0.10
2.3
2.1
—
—
—
0
0
42
398
1.06
0.10
7.8
6.9
5.24
5.06
kpa
0.36
42
383
42
398
1.06
0.10
7.8
6.9
14.17
13.41
kpa
0.38
42
383
5
45
1.11
0.10
1.0
1.7
—
76.38
%
—
0
8
18
164
1.10
0.10
1.6
3.3
—
—
—
0
0
5
48
1.04
0.09
1.0
1.5
—
—
—
0
0
111
1139
0.97
0.09
1.8
1.7
3.25
3.24
ratio
0.03
77
825
23
214
1.08
0.08
4.0
6.0
24.63
24.38
mmol/l
0.15
23
206
22
205
1.08
0.08
8.7
8.0
24.59
24.43
mmol/l
0.09
22
199
7
81
0.86
0.07
1.1
1.6
—
—
—
0
0
16
173
0.92
0.06
1.1
1.2
—
—
—
0
0
16
148
1.08
0.06
3.1
4.7
0.94
0.90
%
0.18
16
142
51
527
0.97
0.06
4.7
4.3
0.92
0.95
%
0.04
12
122
28
292
0.96
0.04
1.8
2.2
67.89
67.47
g/l
0.09
28
276
41
398
1.03
0.04
8.0
7.0
7.44
7.42
ph
0.93
23
221
34
330
1.03
0.03
2.0
2.5
4.59
4.62
kpa
0.03
34
323
11
118
0.93
0.02
1.3
2.6
1.02
0.93
nmol/l
0.22
11
101
50
510
0.98
0.02
4.7
4.4
0.30
0.09
%
—
10
103
128
1270
1.01
0.01
2.8
3.5
28.24
49.02
mg/l
0.93
77
823
51
518
0.98
0.01
4.9
4.8
0.00
0.11
%
—
9
98
34
347
0.98
0.01
2.3
2.0
5.30
6.29
iu/ml
—
9
79
35
344
1.02
0.00
1.5
1.5
0.23
0.26
mg/l
0.09
11
140
11
115
0.96
0.00
1.9
2.0
—
—
—
0
0
12
124
0.97
0.00
1.1
1.1
—
—
—
0
0
15
147
1.02
0.00
1.2
1.5
34.54
33.40
nmol/l
0.05
15
133
51
505
1.01
0.00
4.4
4.2
0.27
0.75
%
1.20
11
114
16
159
1.01
0.00
3.1
4.6
1.43
1.63
%
0.60
16
152
19
191
0.99
0.00
1.1
1.1
13.22
14.82
au/ml
—
5
58
0
9
0.00
0.00
0.0
1.9
—
49.00
—
0
9
0
9
0.00
0.00
0.0
1.2
—
12.30
—
0
9
0
9
0.00
0.00
0.0
3.6
—
24.99
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
35.06
—
0
5
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
224.00
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.8
—
5.32
—
0
5
8
87
0.92
-0.00
1.1
1.3
—
—
—
0
0
9
97
0.93
-0.00
2.7
1.6
0.50
0.48
e9/l
—
9
97
0
5
0.00
-0.00
0.0
1.0
—
7300.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
0.07
—
0
7
8
87
0.92
-0.00
2.3
1.7
59.12
59.86
%
—
8
87
0
7
0.00
-0.00
0.0
1.3
—
1.47
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
92.48
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
27.90
—
0
6
0
7
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
3.00
—
0
8
0
6
0.00
-0.00
0.0
2.5
—
6.72
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
104.40
—
0
5
8
79
1.01
-0.00
1.0
1.5
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.3
108.60
66.88
ug/l
—
5
52
0
5
0.00
-0.00
0.0
1.6
—
302.20
—
0
5
8
89
0.90
-0.00
3.3
2.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
71.17
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
34.48
—
0
6

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_CONGEN_MALFO_BREAST_WIDE – Congenital malformations of breast, including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).