This is a non-core endpoint: only basic statistics are computed.
Frostbite with tissue necrosis
ST19_FROST_W_TISSUE_NECROS
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
127 |
4. Check minimum number of eventsNone |
127 |
5. Include endpointsNone |
127 |
6. Filter based on genotype QC (FinnGen only) |
113 |
Control definitions (FinnGen only)
- Control exclude
- ST19_FROSTBITE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- T3[3-5]
- Name in latin
- Congelatio cum necrosi textus
Similar endpoints
↥List of similar endpoints to
Frostbite with tissue necrosis
based on the number of shared cases.
Similar with more cases:
- Frostbite
- Injury, poisoning and certain other consequences of external causes
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 113 | 36 | 77 |
| Unadjusted period prevalence (%) | 0.03 | 0.01 | 0.04 |
| Median age at first event (years) | 50.29 | 40.56 | 54.84 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 119
- Matched controls
- 1190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X31
ICD-10 Finland
Exposure to excessive natural cold
+∞
67.2
58
*
T34.8
ICD-10 Finland
Frostbite with tissue necrosis of ankle and foot
+∞
50.7
45
*
T34.5
ICD-10 Finland
Frostbite with tissue necrosis of wrist and hand
+∞
39.8
36
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
17.3
37.5
35
28
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
9.3
24.9
36
53
N07BB01
ATC
disulfiram; oral
9.0
18.1
25
34
T68
ICD-10 Finland
Hypothermia
196.4
17.0
17
*
N05AH03
ATC
olanzapine; systemic
7.3
15.5
26
44
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
19.3
14.1
21
13
N05AH04
ATC
quetiapine; oral
4.7
14.0
44
132
T33.5
ICD-10 Finland
Superficial frostbite of wrist and hand
+∞
13.8
13
*
T34.4
ICD-10 Finland
Frostbite with tissue necrosis of arm
+∞
13.8
13
*
NDQ20
NOMESCO Finland
Amputation of finger
157.2
13.8
14
*
X59
ICD-10 Finland
Exposure to unspecified factor
4.4
13.3
46
148
T36
ICD-10 Finland
Poisoning by systemic antibiotics
14.7
13.3
22
18
T33.8
ICD-10 Finland
Superficial frostbite of ankle and foot
+∞
12.7
12
*
X58
ICD-10 Finland
Exposure to other specified factors
4.4
12.1
39
118
T34.9
ICD-10 Finland
Frostbite with tissue necrosis of other and unspecified sites
+∞
11.6
11
*
ZZA00
NOMESCO Finland
Split skin graft
22.8
11.5
16
8
NHQ40
NOMESCO Finland
Amputation of toe
18.2
10.7
16
10
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
+∞
10.6
10
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
10.2
10.3
20
23
P15
ICPC
Chronic alcohol abuse
10.5
10.0
19
21
S97
ICPC
Chronic ulcer skin
5.8
9.5
19
38
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
12.1
9.1
16
15
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.1
9.1
29
86
J01FF01
ATC
clindamycin; systemic
3.2
8.7
49
211
A46
ICD-10 Finland
Erysipelas
3.8
8.6
31
100
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
36.1
8.2
10
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.7
8.2
21
52
N05CD07
ATC
temazepam; oral
4.5
8.1
22
57
X39
ICD-10 Finland
Exposure to other and unspecified forces of nature
85.2
7.5
8
*
T34.7
ICD-10 Finland
Frostbite with tissue necrosis of knee and lower leg
+∞
7.4
7
*
T34.0
ICD-10 Finland
Frostbite with tissue necrosis of head
+∞
7.4
7
*
T35.4
ICD-10 Finland
Unspecified frostbite of upper limb
+∞
7.4
7
*
N05AA02
ATC
levomepromazine; systemic
8.0
7.0
15
21
AA1AD
NOMESCO Finland
CT of head and brain
2.9
6.9
46
213
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
9.6
6.7
13
15
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.3
6.5
18
47
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
10.1
6.5
12
13
F10.25
ICD-10 Finland
Alcohol dependence continuous use
10.1
6.5
12
13
N05BA04
ATC
oxazepam; oral
2.9
6.4
40
178
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
19.3
6.4
9
5
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
+∞
6.3
6
*
T35.5
ICD-10 Finland
Unspecified frostbite of lower limb
+∞
6.3
6
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.5
6.2
24
80
SPAT1254
SPAT
Administration of medicine
3.4
6.2
25
86
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
6.1
31
123
EBA00
NOMESCO Finland
Extraction of tooth
2.6
6.0
55
296
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.9
6.0
19
55
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
146
2.74
5.25
2.5
2.0
1.84
1.44
%
1.20
28
128
25
98
2.96
4.94
6.0
4.7
1.37
1.27
mmol/l
0.03
18
78
27
112
2.82
4.82
13.4
14.6
-0.62
0.78
mmol/l
0.46
20
96
20
70
3.23
4.77
2.8
1.6
0.42
0.29
mg/l
0.47
15
33
40
232
2.09
3.33
5.0
3.3
1.02
1.02
kg/l
0.67
30
148
30
160
2.17
3.07
1.7
1.6
946.54
1195.48
nmol/l
1.12
24
127
19
86
2.44
2.82
10.8
11.4
1.34
1.28
mmol/l
0.11
19
86
31
178
2.00
2.60
1.7
2.0
—
—
—
0
0
26
147
1.98
2.26
12.7
8.8
104.27
104.41
mmol/l
0.04
26
147
24
135
1.97
2.11
1.6
1.8
—
—
—
0
0
23
130
1.95
1.99
1.6
2.0
—
—
—
0
0
8
30
2.78
1.76
1.1
1.2
—
—
—
0
0
14
71
2.10
1.61
1.5
1.6
—
—
—
0
0
14
71
2.10
1.61
17.9
13.6
1.42
1.35
%
0.08
14
71
14
73
2.04
1.51
2.9
2.7
85.33
58.21
ml/min/173m2
—
6
29
13
68
2.02
1.39
19.1
14.0
0.56
0.71
%
1.06
13
68
28
394
0.62
1.37
3.5
4.4
30.20
22.19
%
1.13
12
173
51
395
1.51
1.36
2.7
2.0
90.71
95.89
pmol/l
0.50
36
198
20
305
0.59
1.36
3.1
3.1
0.63
0.76
ug/l
0.44
14
192
28
193
1.59
1.24
1.4
1.7
517.29
451.32
pmol/l
0.36
21
174
57
460
1.46
1.21
3.0
3.1
—
—
estimate
—
0
0
5
110
0.43
1.20
1.4
1.9
424.00
401.43
nmol/l
—
5
102
10
50
2.09
1.20
1.5
1.3
—
—
—
0
0
6
26
2.37
1.20
13.8
4.7
3.58
4.02
mmol/l
—
6
26
11
58
1.99
1.16
1.6
1.8
—
—
—
0
0
7
30
2.41
1.14
1.7
1.9
—
—
—
0
0
7
31
2.33
1.12
1.7
2.1
—
—
—
0
0
5
21
2.44
1.10
1.0
1.3
—
—
—
0
0
5
21
2.44
1.10
1.0
1.3
—
—
—
0
0
7
35
2.06
1.02
2.6
1.9
223.29
212.46
%
—
7
35
0
30
0.00
0.99
0.0
1.6
—
—
—
0
0
0
32
0.00
0.96
0.0
1.5
—
0.12
—
0
6
82
900
0.71
0.88
5.7
4.6
2.01
1.92
mu/l
0.15
77
824
57
661
0.74
0.88
3.2
3.3
—
—
—
0
0
87
945
0.70
0.86
20.0
15.1
88.42
84.97
ml/min/173m2
0.60
80
868
16
107
1.57
0.81
6.8
7.1
—
—
—
0
0
25
185
1.44
0.81
2.4
2.8
1.03
0.78
e6/l
0.27
11
98
0
24
0.00
0.80
0.0
1.9
—
—
—
0
0
0
25
0.00
0.80
0.0
1.1
—
—
—
0
0
0
26
0.00
0.79
0.0
1.1
—
—
—
0
0
12
75
1.67
0.78
1.5
2.2
6.52
12.15
ug/l
0.57
12
67
15
101
1.56
0.74
2.7
3.3
—
—
—
0
0
31
244
1.37
0.71
3.0
2.6
—
—
—
0
0
5
28
1.82
0.67
1.0
1.1
—
—
—
0
0
46
389
1.30
0.65
3.0
3.2
25.61
34.39
ng/l
0.56
31
264
61
536
1.28
0.64
4.2
3.5
0.00
0.04
estimate
—
6
104
60
530
1.27
0.59
4.3
3.5
0.00
0.00
estimate
—
7
113
6
35
1.75
0.58
1.5
2.8
—
15131.86
—
0
11
9
59
1.57
0.56
5.7
3.0
1.96
1.29
%
—
9
59
59
525
1.25
0.53
4.3
3.4
0.00
0.00
estimate
—
7
112
10
67
1.54
0.51
8.6
9.9
22.50
24.54
mmol/l
—
10
67
88
933
0.78
0.50
4.4
4.2
1.37
1.30
mmol/l
0.43
82
863
16
206
0.74
0.46
1.6
1.7
—
—
—
0
0
93
975
0.79
0.43
4.8
4.9
1.33
1.37
mmol/l
0.63
88
907
24
197
1.27
0.42
5.9
4.0
70.41
328.05
ng/l
0.91
17
154
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
171.41
—
0
16
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
91
953
0.81
0.38
5.4
4.7
6.25
5.96
mmol/l
0.61
86
879
62
575
1.16
0.31
9.2
11.5
4.57
4.19
e9/l
0.45
55
500
20
167
1.24
0.31
2.4
2.9
4.33
2.00
e6/l
—
6
81
7
57
1.24
0.29
1.1
1.0
—
—
—
0
0
34
302
1.18
0.29
3.5
3.2
0.02
0.41
e6/l
4.40
23
217
9
73
1.25
0.26
3.2
2.1
—
—
—
0
0
32
288
1.15
0.23
5.8
3.7
0.00
0.01
estimate
—
5
105
5
40
1.26
0.22
1.8
1.3
—
—
—
0
0
11
89
1.26
0.21
1.5
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
6.2
—
870.25
—
0
12
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
9.54
—
0
14
35
320
1.13
0.20
4.4
4.5
8.80
11.68
mg/mmol
0.33
27
214
22
246
0.87
0.18
1.6
1.3
3.69
0.87
u/ml
—
7
63
10
82
1.24
0.17
3.4
2.1
—
—
—
0
0
80
828
0.90
0.17
27.1
20.1
13.59
13.57
%
0.06
80
821
5
66
0.75
0.17
1.0
1.2
—
120.25
—
0
17
72
748
0.91
0.16
4.2
3.7
14.83
14.80
pmol/l
0.03
66
674
20
178
1.15
0.16
1.1
1.2
15.50
29.33
iu/ml
—
6
56
14
157
0.88
0.12
2.5
2.2
—
—
—
0
0
25
237
1.07
0.06
1.9
1.6
1.57
1.35
mg/l
0.18
20
183
27
283
0.94
0.06
2.9
3.3
1634.38
1414.82
ng/l
0.08
21
230
75
742
1.03
0.02
4.0
4.0
12.89
10.37
mm/h
0.57
70
688
41
417
0.97
0.01
2.0
2.0
1.21
1.39
mmol/l
1.15
35
354
14
139
1.01
0.00
2.4
2.1
—
—
—
0
0
16
161
0.99
0.00
2.1
2.9
10.28
14.38
umol/l
1.42
16
156
10
102
0.98
0.00
1.4
1.4
—
—
—
0
0
99
995
0.97
0.00
24.1
15.7
30.22
25.05
mg/l
0.96
88
806
40
404
0.99
0.00
4.9
3.3
0.20
0.00
estimate
—
5
99
0
6
0.00
0.00
0.0
1.0
—
0.31
—
0
6
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
193.83
—
0
6
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.5
—
59.67
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
8.8
—
200.14
—
0
5
0
5
0.00
0.00
0.0
3.0
—
38.80
—
0
5
0
9
0.00
-0.00
0.0
1.7
—
7.57
—
0
9
0
7
0.00
-0.00
0.0
2.7
—
13.39
—
0
7
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.7
—
10.01
—
0
8
5
50
1.00
-0.00
1.2
1.8
35.20
42.50
u/l
—
5
44
0
9
0.00
-0.00
0.0
2.7
—
769.67
—
0
9
0
8
0.00
-0.00
0.0
1.0
—
1879.13
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
16
160
1.00
-0.00
1.2
1.3
1.08
6.43
u/ml
—
6
57
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ST19_FROST_W_TISSUE_NECROS – Frostbite with tissue necrosis
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).