No definition available.
Benign neoplasm: Long bones of lower limb
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_BONE_LONG_LOWER
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1420 |
4. Check minimum number of eventsNone |
1420 |
5. Include endpointsNone |
1420 |
6. Filter based on genotype QC (FinnGen only) |
1301 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D16
- Name in latin
- Neoplasma benignum ossium longorum membri inferioris
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Long bones of lower limb
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of bone and articular cartilage
- Benign neoplasms
- Neoplasms
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10196 | 4557 | 5600 |
| Only index persons | 9666 | 4381 | 5285 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.13 | 0.16 |
| Only index persons | 0.18 | 0.16 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 23.26 | 27.03 | 20.08 |
| Only index persons | 23.02 | 26.68 | 19.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1301 | 744 | 557 |
| Unadjusted period prevalence (%) | 0.26 | 0.26 | 0.26 |
| Median age at first event (years) | 37.43 | 38.60 | 35.87 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1338
- Matched controls
- 13380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
57.2
307.7
244
52
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
14349.5
307.7
977
*
9102
FHL
Trepanation or removal of the local bone process
91.4
251.5
132
16
21306
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium longorum extremitatis inferioris
+∞
223.4
208
*
2137A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Long bones of lower limb
+∞
184.8
173
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
69.8
155.7
85
13
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
219.4
117.7
120
6
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
10.2
116.4
137
148
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
49.7
82.5
48
10
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
9.6
73.5
89
99
NF3AA
NOMESCO Finland
Femur X-ray examination
8.7
58.7
76
92
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.3
58.3
254
878
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
3.8
37.8
124
353
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.7
37.3
89
199
NFK10
NOMESCO Finland
Fenestration or partial or total excision of bone of femur
298.2
28.9
29
*
M79.6
ICD-10 Finland
Pain in limb
1.9
28.3
648
4435
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
31.7
28.2
37
12
NF1AA
NOMESCO Finland
Hip X-ray examination
2.9
27.4
135
492
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
25.6
25.3
35
14
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.9
24.5
75
203
NGK05
NOMESCO Finland
Partial or total excision of bone of lower leg
88.4
23.7
26
*
NHR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of ankle or foot
42.3
23.7
29
7
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.0
21.9
272
1495
D16.3
ICD-10 Finland
Benign neoplasm: Short bones of lower limb
61.0
20.9
24
*
WX320
NOMESCO Finland
Spinalanesthesy
1.9
20.7
333
1993
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
8.8
20.7
26
30
ZZH40
NOMESCO Finland
Substitute of bone
7.4
20.0
29
40
9101
FHL
Bone biopsy
40.7
19.5
24
6
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
34.9
18.9
24
7
M25.5
ICD-10 Finland
Pain in joint
1.7
18.9
494
3401
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
101.5
18.6
20
*
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
19.6
16.9
25
13
N02AX02
ATC
tramadol; systemic, rectal
1.6
15.1
537
3942
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
4.1
14.9
41
103
NG1AD
NOMESCO Finland
Knee CT examination
4.3
14.6
37
87
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
14.5
587
4431
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.1
14.2
149
764
Q78.6
ICD-10 Finland
Multiple congenital exostoses
53.9
13.8
16
*
L15
ICPC
Knee symptom/complaint
1.7
13.8
340
2270
N02BE01
ATC
paracetamol; systemic, rectal
1.9
13.7
1173
10541
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
13.7
568
4295
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
141.4
13.5
14
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
141.4
13.5
14
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
13.0
375
2597
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.0
13.0
58
200
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.4
12.9
90
390
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.0
12.8
156
842
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.8
494
3660
N03AX16
ATC
[U] pregabalin
1.7
12.8
286
1856
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
12.5
12
*
N06AX21
ATC
duloxetine; oral
1.9
12.2
175
997
X58
ICD-10 Finland
Exposure to other specified factors
1.7
12.2
232
1440
NFK99
NOMESCO Finland
Other operation on bone of femur
47.1
11.9
14
*
ZXA05
NOMESCO Finland
Left side
1.7
11.9
268
1741
9104
FHL
Autogenous bone graft
65.5
11.6
13
*
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
5.4
11.4
22
41
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.0
11.2
127
668
M85.4
ICD-10 Finland
Solitary bone cyst
17.2
11.2
17
10
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
11.0
551
4277
M54.5
ICD-10 Finland
Low back pain
1.5
11.0
496
3771
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
3.0
10.8
46
155
M12.2
ICD-10 Finland
Villonodular synovitis (pigmented)
28.3
10.7
14
5
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
28.3
10.7
14
5
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
3.1
10.5
43
141
9103
FHL
Partial or complete bone removal
14.3
10.5
17
12
NFA20
NOMESCO Finland
Exploration of hip joint or femur
110.9
10.4
11
*
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
110.9
10.4
11
*
NFR99
NOMESCO Finland
Other operation for tumour of hip or thigh
+∞
10.4
10
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.6
10.4
34
97
M01AH05
ATC
etoricoxib; oral
1.5
10.3
817
6903
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.5
10.2
35
103
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
9.9
310
2170
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
9.9
321
2267
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
26.2
9.8
13
5
D16.8
ICD-10 Finland
Benign neoplasm: Pelvic bones, sacrum and coccyx
20.2
9.8
14
7
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
9.8
113
599
L13
ICPC
Hip symptom/complaint
1.6
9.6
222
1444
M01AE02
ATC
naproxen; oral, rectal
1.4
9.5
740
6187
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
9.4
141
814
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
13.8
9.2
15
11
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
8.8
133
768
B01AB05
ATC
enoxaparin; parenteral
1.5
8.7
342
2504
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
8.7
221
1472
M01AE01
ATC
ibuprofen; systemic, rectal
1.8
8.6
1212
11296
J01AA02
ATC
doxycycline; systemic
1.5
8.6
953
8424
SPAT1153
SPAT
Removal of sutures
1.5
8.6
344
2528
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
8.5
402
3053
NGK99
NOMESCO Finland
Other operation on bone of knee or lower leg
20.2
8.5
12
6
M85.0
ICD-10 Finland
Fibrous dysplasia (monostotic)
90.6
8.4
9
*
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
90.6
8.4
9
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
90.6
8.4
9
*
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
8.3
8
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.0
8.2
84
426
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
14.6
8.2
13
9
M22.4
ICD-10 Finland
Chondromalacia patellae
2.5
8.1
50
206
S18
ICPC
Laceration/cut
1.4
8.1
563
4573
N02BF02
ATC
pregabalin; oral
2.0
7.9
90
475
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.6
7.8
43
167
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
2.0
7.8
86
449
D16
ICD-10 Finland
Benign neoplasm of bone and articular cartilage
45.2
7.7
9
*
NK6DT
NOMESCO Finland
Bone biopsy with MRI guidance
45.2
7.7
9
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
45.2
7.7
9
*
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.2
7.7
30
96
M03BX02
ATC
tizanidine; oral
1.4
7.7
793
6850
NG1AA, ,
SPAT
1.8
7.7
120
701
SPAT1312
SPAT
General health counselling
1.4
7.6
385
2947
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
11.9
7.6
13
11
NG1BG, ,
SPAT
2.1
7.5
73
364
S83.4
ICD-10 Finland
Sprain and strain involving (fibular)(tibial) collateral ligament of knee
2.3
7.5
53
232
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.5
153
964
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
7.4
237
1659
AA1AD
NOMESCO Finland
CT of head and brain
1.5
7.4
300
2205
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.4
419
3274
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.4
245
1729
Q78.1
ICD-10 Finland
Polyostotic fibrous dysplasia
+∞
7.3
7
*
NGR99
NOMESCO Finland
Other operation for tumour of knee or lower leg
+∞
7.3
7
*
Q78.48
ICD-10 Finland
Enchondromatosis
+∞
7.3
7
*
M02AA07
ATC
piroxicam; topical
1.4
7.3
371
2843
A02BC02
ATC
pantoprazole; systemic
1.4
7.3
816
7116
M01AB05
ATC
diclofenac; systemic, rectal
1.4
7.2
817
7127
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.0
7.2
72
363
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.2
312
2321
NF3BA
NOMESCO Finland
Femur extensive X-ray examination
12.1
7.1
12
10
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
12.1
7.1
12
10
Z47.8
ICD-10 Finland
Other specified orthopaedic follow-up care
6.1
7.1
18
30
S83.2
ICD-10 Finland
Tear of meniscus, current
1.9
7.0
93
516
NG4AD
NOMESCO Finland
Lower leg CT
10.1
7.0
13
13
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
7.0
719
6165
J01DB01
ATC
cefalexin; oral
1.5
7.0
1067
9765
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.9
397
3102
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
2.1
6.9
66
328
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
6.9
286
2108
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.1
6.9
62
301
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.7
6.8
128
788
J01FF01
ATC
clindamycin; systemic
1.4
6.8
313
2353
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.7
114
683
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.7
129
800
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.6
6.7
168
1114
R93.7
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
12.3
6.6
11
9
Z00.0
ICD-10 Finland
General medical examination
1.5
6.5
235
1686
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
3.5
6.4
21
60
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
3.2
6.4
24
75
NJ3DG
NOMESCO Finland
Very extensive MRI examination of extremities with high intensity magnet
70.2
6.4
7
*
M93.8
ICD-10 Finland
Other specified osteochondropathies
+∞
6.3
6
*
NF3AA, ,
SPAT
+∞
6.3
6
*
M23.8
ICD-10 Finland
Other internal derangements of knee
2.1
6.2
53
252
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
6.2
222
1587
L16
ICPC
Ankle symptom/complaint
1.6
6.2
154
1018
M01AH01
ATC
celecoxib; oral
1.5
6.1
183
1260
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
3.5
6.0
20
58
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
668
5431
1.46
10.33
2.8
2.7
—
—
estimate
—
0
0
205
1285
1.70
10.28
4.4
4.4
31.95
31.45
%
0.24
137
894
973
8540
1.51
9.97
5.2
4.2
10.09
10.39
mm/h
0.30
909
8059
182
1142
1.69
9.05
7.1
6.1
—
—
—
0
0
645
5371
1.39
7.90
8.5
7.4
1.21
1.21
mmol/l
0.32
553
4677
366
2792
1.43
7.36
2.4
2.3
—
—
—
0
0
577
4769
1.37
7.17
11.9
11.8
1.18
1.18
inr
0.14
465
3953
962
8695
1.38
6.35
9.3
8.1
77.89
77.50
u/l
0.10
923
8310
569
4785
1.33
5.96
7.7
6.8
1.21
1.21
mmol/l
0.26
522
4455
1219
11552
1.62
5.94
16.8
14.2
20.87
22.49
mg/l
1.12
1022
9389
56
282
2.03
5.67
1.5
1.7
24863.87
10997.28
e6/l
0.90
45
202
415
3357
1.34
5.59
2.4
2.1
195.37
211.10
u/l
0.18
399
3202
825
7370
1.31
5.35
5.0
4.3
117.33
1512.62
e6/l
—
6
101
152
1042
1.52
5.19
2.8
2.4
0.22
0.22
g/l
0.16
147
979
681
5949
1.29
5.13
6.8
6.6
10.98
11.38
umol/l
0.28
647
5685
562
4789
1.30
5.11
5.3
5.1
36.56
36.46
g/l
0.17
517
4528
16
45
3.59
5.05
3.3
2.1
76.81
72.01
ug/l
0.07
16
45
488
4088
1.30
5.02
3.7
3.4
17.67
55.52
ng/l
1.70
314
2587
57
306
1.90
4.85
1.5
1.4
—
—
—
0
0
27
107
2.55
4.81
1.3
1.4
16721.69
187969.44
e6/l
1.22
13
79
743
6603
1.28
4.73
5.4
5.3
6.47
6.58
mmol/l
0.88
704
6213
144
996
1.50
4.72
2.7
2.8
10.52
10.58
g/l
0.08
136
923
304
2402
1.34
4.68
1.4
1.3
24.69
27.60
iu/ml
0.21
97
714
363
2944
1.32
4.67
2.8
2.6
331.80
337.07
umol/l
0.47
331
2653
116
773
1.55
4.52
3.4
4.2
68.74
84.51
ng/l
1.61
104
698
118
793
1.54
4.43
2.7
2.9
67.05
67.28
g/l
0.15
108
744
751
6728
1.26
4.29
10.1
9.6
3.98
4.04
e9/l
0.26
668
5896
404
3358
1.29
4.28
4.3
3.7
0.01
0.01
estimate
0.02
128
1211
87
552
1.62
4.19
2.3
2.0
6.43
7.24
iu/ml
0.12
26
136
137
965
1.47
4.12
4.1
4.7
32.36
27.18
ug/l
0.06
112
784
705
6291
1.26
4.08
4.0
3.6
2.21
0.01
estimate
0.49
136
1203
428
3614
1.27
3.94
2.8
2.7
53.96
60.64
u/l
2.23
389
3379
277
2217
1.31
3.85
1.4
1.3
7.40
9.96
u/ml
0.45
115
895
920
8499
1.26
3.80
4.0
3.3
45.74
46.34
u/l
0.09
871
8118
691
6189
1.24
3.73
4.0
3.5
0.00
0.00
estimate
0.50
134
1280
158
1172
1.39
3.60
4.3
4.6
229.97
245.44
u/l
0.84
153
1120
696
6254
1.24
3.59
4.0
3.6
0.01
5.01
estimate
1.32
135
1286
1202
11538
1.41
3.57
18.9
15.9
139.65
139.67
mmol/l
0.12
1178
11316
1155
11044
1.33
3.27
15.2
13.2
87.66
87.33
ml/min/173m2
0.22
1067
10108
1202
11567
1.39
3.24
19.0
16.0
3.95
3.95
mmol/l
0.11
1176
11319
64
405
1.61
3.18
2.3
1.7
1.15
1.20
g/l
0.71
59
385
20
85
2.37
3.16
2.3
2.1
—
—
—
0
0
62
392
1.61
3.10
2.4
1.7
0.21
0.23
g/l
1.81
56
373
59
369
1.63
3.08
1.5
1.2
2.48
2.63
u/ml
—
6
35
332
2793
1.25
3.05
3.1
3.2
1039.30
1051.32
ng/l
0.02
274
2334
59
370
1.62
3.05
1.5
1.3
3.66
9.64
u/ml
—
9
63
39
219
1.80
2.99
1.7
1.6
—
—
—
0
0
80
544
1.50
2.92
2.1
2.1
40.46
39.18
u/l
0.23
71
497
977
9201
1.23
2.83
4.7
4.3
14.73
14.57
pmol/l
1.27
909
8562
213
1722
1.28
2.72
1.8
1.9
—
—
—
0
0
16
66
2.44
2.71
1.4
3.2
755.75
775.32
u/ml
0.03
16
66
84
588
1.46
2.68
1.7
1.6
—
—
—
0
0
108
792
1.40
2.67
2.8
3.5
4.53
4.61
pmol/l
0.39
95
709
152
1180
1.33
2.62
2.3
2.4
14.04
13.40
nmol/l
0.44
138
1083
325
2771
1.23
2.61
1.7
1.5
2.14
2.32
g/l
1.40
225
1783
1118
10714
1.26
2.60
6.4
5.7
38.13
38.51
mmol/mol
0.93
1052
10180
1139
10944
1.27
2.56
5.1
4.6
5.80
5.85
mmol/l
0.86
1046
10217
59
388
1.54
2.55
2.1
2.3
490.73
312.17
ug/l
0.23
54
364
116
870
1.36
2.52
1.4
1.5
—
—
—
0
0
39
232
1.70
2.51
1.7
1.7
—
—
—
0
0
55
358
1.56
2.49
1.4
1.8
—
—
—
0
0
7
16
4.39
2.47
2.1
1.7
—
—
—
0
0
339
2918
1.22
2.47
4.1
4.1
91.50
92.62
%
0.38
329
2855
26
138
1.90
2.42
1.5
1.3
—
—
—
0
0
1256
12250
1.41
2.41
20.9
17.5
74.89
74.70
umol/l
0.07
1250
12127
181
1459
1.28
2.38
6.8
6.3
1.04
1.03
mmol/l
0.02
172
1364
53
349
1.54
2.30
1.5
1.5
251.95
287.21
ug/g
0.68
32
206
423
3742
1.19
2.28
3.3
3.4
2.35
2.35
mmol/l
0.00
385
3451
6
13
4.63
2.27
2.2
1.8
—
—
—
0
0
579
5267
1.18
2.23
2.9
2.5
77.87
74.71
nmol/l
1.37
524
4849
23
121
1.92
2.21
1.7
1.7
48.31
56.85
%
0.45
16
86
16
73
2.21
2.21
1.3
1.3
—
—
—
0
0
207
1711
1.25
2.21
2.6
2.4
2.44
2.37
g/l
1.02
195
1588
526
4758
1.17
2.16
2.1
2.0
101.89
96.77
pmol/l
1.33
280
2591
115
885
1.33
2.14
2.5
2.4
75.73
72.69
ml/min/173m2
0.40
62
368
258
2194
1.22
2.11
1.7
1.7
424.46
31818608.06
pmol/l
2.14
217
1892
91
678
1.37
2.10
1.9
1.7
0.28
0.32
mg/l
0.33
41
333
889
8397
1.17
2.07
3.5
3.3
—
—
—
0
0
648
5974
1.16
2.06
3.2
3.1
115.29
110.78
ug/l
0.22
611
5642
46
302
1.54
2.05
2.0
3.6
33.89
64.41
mg/l
0.84
41
258
46
302
1.54
2.05
2.0
3.6
37.12
46.08
mg/l
0.29
41
258
524
4754
1.17
2.05
4.1
3.4
0.05
0.02
estimate
0.32
125
1079
1118
10781
1.23
2.04
5.7
5.2
1.78
1.84
mu/l
1.14
1043
10146
58
401
1.47
2.03
1.4
1.3
—
—
—
0
0
1189
11550
1.26
1.97
5.6
5.3
2.77
2.78
mmol/l
0.14
1115
10925
7
21
3.35
1.96
1.1
1.1
4.64
5.62
nmol/l
—
7
21
200
1673
1.23
1.92
2.0
2.2
30.02
29.33
s
0.53
190
1627
1122
10840
1.22
1.91
4.3
4.0
1.26
1.30
mmol/l
1.19
1043
10185
210
1768
1.22
1.90
2.4
2.6
87.56
110.08
ug/g
0.67
166
1421
242
2069
1.21
1.88
3.3
3.7
423.21
514.61
ng/l
0.14
158
1454
428
3845
1.17
1.86
3.8
3.5
8.05
8.17
mmol/l
0.17
366
3328
56
392
1.45
1.86
1.7
1.9
—
—
—
0
0
23
129
1.80
1.86
1.3
1.9
22.37
21.85
nmol/l
0.06
23
122
1174
11404
1.24
1.84
5.1
4.7
1.44
1.44
mmol/l
0.34
1098
10777
110
862
1.30
1.83
2.5
2.4
22.25
20.78
au/ml
—
8
99
310
2721
1.18
1.79
2.0
1.8
0.98
1.08
mg/l
0.40
242
2054
186
1557
1.23
1.79
2.7
2.5
24.50
23.61
%
0.35
172
1461
19
102
1.88
1.76
1.1
1.1
—
—
—
0
0
6
18
3.34
1.74
1.3
1.1
—
—
—
0
0
1177
11449
1.23
1.73
5.1
4.8
4.66
4.69
mmol/l
0.48
1107
10878
356
3173
1.17
1.70
1.4
1.3
0.84
1.56
u/ml
1.86
101
896
45
308
1.48
1.70
1.5
1.2
47.28
39.44
u/ml
—
6
30
24
141
1.71
1.69
1.3
1.4
—
—
—
0
0
24
141
1.71
1.69
1.3
1.4
—
—
—
0
0
17
90
1.90
1.65
1.2
1.7
—
—
—
0
0
24
142
1.70
1.65
1.3
1.4
—
—
—
0
0
337
3000
1.16
1.63
1.7
1.6
18.97
20.27
nmol/l
0.88
285
2592
208
1780
1.20
1.61
1.9
1.9
1.48
1.46
%
0.15
183
1592
22
128
1.73
1.61
1.3
1.3
—
—
—
0
0
143
1181
1.24
1.58
10.3
10.1
12.64
12.51
kpa
0.11
136
1142
143
1181
1.24
1.58
10.3
10.1
5.14
5.12
kpa
0.11
136
1138
153
1274
1.23
1.56
1.8
1.8
—
—
—
0
0
54
390
1.40
1.56
6.2
3.5
1.30
1.40
mg/l
0.54
49
357
47
331
1.44
1.56
2.9
2.7
—
—
—
0
0
10
44
2.28
1.55
2.0
2.3
—
—
—
0
0
19
107
1.79
1.55
1.2
1.1
—
—
—
0
0
369
3321
1.15
1.54
5.4
4.7
1.82
1.99
ug/l
0.45
334
3046
44
307
1.45
1.53
1.7
1.7
—
—
—
0
0
212
1828
1.19
1.51
2.6
2.5
14.33
13.87
umol/l
0.36
202
1713
24
146
1.66
1.51
1.3
1.3
—
—
—
0
0
1245
12213
1.28
1.51
13.5
11.3
28.05
27.21
u/l
0.85
1212
11937
102
816
1.27
1.49
4.9
3.8
1.22
1.23
mmol/l
0.15
86
710
20
116
1.74
1.49
1.8
2.2
17.38
19.54
mg/l
—
8
47
81
629
1.31
1.48
4.1
3.2
1.58
1.58
mmol/l
0.00
67
466
65
489
1.35
1.48
1.7
1.6
16.82
10.94
u/ml
0.19
12
123
9
37
2.44
1.48
2.0
1.8
40.82
41.78
g/l
—
9
37
140
1165
1.23
1.45
10.3
10.3
1.17
0.92
mmol/l
0.44
116
970
182
1555
1.20
1.44
1.7
1.7
1139.83
1169.81
nmol/l
0.18
133
1202
5
16
3.13
1.44
1.6
2.2
—
—
—
0
0
19
110
1.74
1.43
1.1
1.1
—
—
—
0
0
19
110
1.74
1.43
1.1
1.1
—
—
—
0
0
24
149
1.62
1.41
1.3
1.3
—
—
—
0
0
24
149
1.62
1.41
1.3
1.3
—
—
—
0
0
222
1934
1.18
1.41
2.4
2.1
—
—
—
0
0
15
81
1.86
1.40
2.1
3.1
438.40
1394.41
mg
2.14
15
81
119
978
1.24
1.39
1.3
1.2
84.95
141.80
u/ml
1.66
46
388
39
272
1.45
1.38
1.9
3.4
1.17
2.26
ratio
2.44
26
153
52
383
1.37
1.37
1.7
2.1
3.30
3.71
g/l
1.59
45
362
23
143
1.62
1.35
1.4
1.3
0.21
0.17
nmol/l
0.91
18
110
52
384
1.37
1.35
1.8
2.1
7.18
7.20
g/l
0.03
45
362
52
384
1.37
1.35
1.8
2.1
4.09
4.26
g/l
0.86
45
362
213
1858
1.17
1.34
4.5
3.5
0.83
0.82
mmol/l
0.63
194
1770
327
2952
1.14
1.30
2.3
2.2
2.82
2.72
mg/l
0.40
277
2570
56
422
1.34
1.29
1.9
1.9
0.97
1.98
ug/l
0.68
49
379
86
688
1.27
1.29
2.7
2.4
5111.99
5856.34
u/l
0.11
29
286
12
63
1.91
1.23
1.0
1.1
581.09
216.39
iu/ml
0.35
12
63
19
116
1.65
1.21
1.1
1.1
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
5.38
7.11
u/ml
—
5
19
25
165
1.52
1.18
1.3
1.2
—
—
—
0
0
17
102
1.68
1.16
1.6
1.5
—
—
—
0
0
48
360
1.35
1.16
1.3
1.3
—
—
—
0
0
15
87
1.73
1.15
2.3
2.2
453.70
637.36
e6/l
—
10
70
388
3568
1.12
1.15
3.5
3.0
0.25
0.01
estimate
0.58
120
1045
27
183
1.49
1.14
1.1
1.3
—
—
—
0
0
39
284
1.38
1.13
4.1
3.0
8.22
8.33
kpa
0.13
39
279
18
111
1.63
1.12
1.1
1.1
27.44
42.54
mg/l
2.16
18
86
8
40
2.01
1.12
1.4
1.4
9.78
8.42
ug/l
—
8
40
125
1061
1.20
1.10
10.8
10.8
96.61
95.90
%
1.37
119
1028
37
269
1.39
1.09
1.7
2.4
1.00
0.88
nmol/l
0.31
29
236
40
535
0.74
1.09
1.5
1.5
—
—
—
0
0
373
3432
1.12
1.09
4.2
4.2
6.07
9.56
mg/mmol
1.63
234
2185
15
89
1.69
1.07
1.5
1.5
—
—
—
0
0
91
751
1.23
1.07
1.1
1.1
—
—
—
0
0
231
2067
1.14
1.06
1.5
1.5
—
—
—
0
0
48
367
1.32
1.04
1.6
2.1
2.53
2.90
g/l
2.08
41
345
17
106
1.61
1.03
1.0
1.1
225.82
255.30
mg/l
0.52
17
92
1288
12739
1.30
1.02
25.9
21.3
90.59
90.57
fl
0.05
1283
12634
1288
12741
1.29
1.00
26.0
21.4
4.54
4.56
e12/l
0.86
1272
12511
1288
12741
1.29
1.00
26.5
21.9
40.77
41.24
%
0.66
1282
12627
17
107
1.60
1.00
1.1
1.1
—
—
—
0
0
1287
12731
1.29
0.99
26.1
21.4
257.02
254.19
e9/l
0.90
1274
12526
233
2096
1.14
0.99
2.5
2.3
—
—
—
0
0
271
2463
1.13
0.98
2.8
2.6
6.27
6.04
e6/l
0.09
247
2250
1288
12745
1.28
0.96
26.0
21.4
6.74
6.69
e9/l
0.24
1272
12506
26
182
1.44
0.96
1.5
2.0
—
1751.11
—
0
9
1288
12746
1.28
0.95
26.1
21.5
136.42
137.14
g/l
1.08
1283
12637
44
338
1.31
0.94
1.7
2.2
0.82
0.89
g/l
0.04
34
309
303
2778
1.12
0.94
1.7
1.6
—
—
—
0
0
45
347
1.31
0.94
1.1
1.1
3.85
3.02
u/ml
0.11
22
198
6
27
2.23
0.93
1.0
1.1
111.67
97.81
%
—
6
27
54
428
1.27
0.93
1.5
1.5
0.05
0.05
iu/ml
0.04
11
59
12
70
1.72
0.92
1.3
1.1
—
—
—
0
0
37
278
1.34
0.92
4.7
5.9
1511.80
284.14
iu/ml
—
5
35
57
455
1.26
0.92
1.6
1.5
—
—
—
0
0
15
232
0.64
0.92
1.6
1.5
—
—
—
0
0
39
296
1.33
0.91
1.0
1.1
0.81
1.59
u/ml
0.53
14
136
45
349
1.30
0.91
1.2
1.1
4.63
3.87
—
7
54
140
1223
1.16
0.91
1.9
1.9
—
—
—
0
0
40
305
1.32
0.91
1.0
1.1
4.82
5.82
u/ml
0.20
17
175
97
823
1.19
0.89
1.6
1.5
21.16
24.51
iu/l
0.49
84
694
38
293
1.31
0.82
1.3
1.5
—
10.15
—
0
5
65
536
1.22
0.82
1.9
1.8
—
—
—
0
0
33
250
1.33
0.80
2.5
2.3
132.93
130.77
g/l
0.19
27
204
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
8
48
1.67
0.78
1.3
1.1
53.91
42.84
u/ml
—
8
48
8
48
1.67
0.78
1.3
1.2
—
—
—
0
0
8
48
1.67
0.78
1.3
1.2
—
—
—
0
0
383
3589
1.09
0.78
3.5
3.2
27.14
67.34
e6/l
1.34
303
2733
16
234
0.68
0.78
1.3
1.7
—
—
—
0
0
209
1899
1.12
0.78
3.1
2.8
0.79
1.05
e6/l
1.01
118
990
42
332
1.27
0.77
1.7
2.0
9.98
10.29
g/l
0.16
34
308
57
468
1.23
0.76
7.1
5.9
2.03
1.56
%
0.52
52
439
10
59
1.70
0.76
1.2
1.3
—
—
—
0
0
10
59
1.70
0.76
1.2
1.3
—
—
—
0
0
20
141
1.42
0.74
3.2
1.5
282.13
280.71
mosm/kgh2o
0.06
15
111
5
24
2.09
0.74
1.0
1.3
—
—
—
0
0
19
133
1.43
0.73
1.1
1.1
—
—
—
0
0
7
38
1.85
0.73
1.0
1.1
—
—
—
0
0
7
39
1.80
0.72
1.1
2.0
12.44
16.84
umol/l
—
7
39
10
60
1.67
0.72
1.9
1.5
206.00
179.83
mmol/24h
—
10
60
17
241
0.70
0.71
2.8
2.4
107.70
130.88
ug/min
0.09
11
144
15
101
1.49
0.70
1.1
1.1
3.18
5.16
iu/ml
—
5
28
7
41
1.71
0.70
1.3
1.0
—
—
—
0
0
66
556
1.20
0.69
1.1
1.1
0.58
0.69
ratio
—
6
57
12
181
0.66
0.69
1.7
1.6
—
—
—
0
0
28
213
1.32
0.68
9.0
9.3
106.00
105.32
mmol/l
0.44
23
190
78
669
1.18
0.68
2.7
2.8
164.96
156.21
ng/l
0.07
70
603
31
240
1.30
0.68
1.0
1.1
5.85
5.55
u/ml
—
10
111
26
197
1.33
0.66
2.7
2.2
5.09
5.01
umol/l
0.02
17
145
32
250
1.29
0.66
1.2
1.1
20.52
18.56
au/ml
0.10
13
76
120
1067
1.14
0.65
3.5
3.1
—
—
—
0
0
192
1756
1.11
0.65
3.2
2.9
2.41
2.52
e6/l
0.09
103
846
47
386
1.23
0.65
1.0
1.1
0.64
4.73
eliau/ml
—
5
54
330
3101
1.09
0.63
3.6
3.1
0.30
0.36
e6/l
0.33
256
2254
25
325
0.76
0.63
1.8
1.6
—
—
—
0
0
114
1014
1.14
0.62
3.6
3.7
2.13
1.80
mmol/l
0.68
105
875
49
407
1.21
0.61
1.8
2.4
91.80
94.79
%
0.46
49
395
34
423
0.80
0.61
1.4
1.5
—
—
—
0
0
8
51
1.57
0.60
1.0
1.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
151
1371
1.11
0.60
3.3
2.8
5.76
8.10
umol/l
1.59
130
1210
134
1209
1.12
0.59
2.1
2.2
374.50
377.47
nmol/l
0.05
125
1141
0
22
0.00
0.59
0.0
2.0
—
2.18
—
0
12
109
972
1.13
0.58
9.2
9.7
1.28
1.32
mmol/l
0.19
109
956
35
431
0.81
0.58
1.3
1.5
1.16
1.19
ratio
0.07
26
272
35
431
0.81
0.58
1.3
1.5
1.05
0.95
ratio
0.24
26
272
35
431
0.81
0.58
1.3
1.5
1.47
1.19
ratio
0.77
26
272
16
219
0.73
0.58
1.3
1.5
—
—
—
0
0
25
319
0.78
0.56
1.8
1.6
—
—
—
0
0
54
458
1.19
0.56
1.3
1.5
—
—
—
0
0
15
206
0.73
0.55
1.6
1.8
—
—
—
0
0
18
133
1.36
0.55
1.1
1.1
—
—
—
0
0
20
151
1.33
0.54
1.1
1.1
—
—
—
0
0
439
4197
1.07
0.53
3.6
3.4
33.96
31.86
u/l
0.51
423
3987
218
2030
1.09
0.53
2.9
2.8
2.44
2.44
mmol/l
0.04
195
1827
90
799
1.14
0.53
1.9
2.3
5.77
7.53
ug/l
0.71
77
725
11
157
0.70
0.51
1.4
1.6
—
—
—
0
0
27
215
1.26
0.51
1.1
1.2
2.71
4.75
u/ml
0.85
17
92
9
65
1.39
0.50
1.0
1.1
—
—
—
0
0
33
270
1.23
0.50
1.4
1.5
152.00
152.59
au/ml
0.01
12
77
21
268
0.78
0.49
1.5
1.5
—
—
—
0
0
35
289
1.22
0.49
2.7
2.9
1.29
2.12
index
0.51
21
170
22
279
0.78
0.49
1.4
1.3
—
—
—
0
0
67
587
1.15
0.49
1.5
1.5
—
—
—
0
0
7
46
1.52
0.48
1.7
1.8
—
—
—
0
0
7
46
1.52
0.48
1.7
1.8
—
—
—
0
0
7
47
1.49
0.47
1.7
1.7
—
—
—
0
0
7
47
1.49
0.47
1.7
1.6
—
—
—
0
0
7
47
1.49
0.47
1.0
1.3
—
—
—
0
0
58
504
1.16
0.47
1.6
1.5
7.62
8.64
u/l
0.33
47
413
10
68
1.47
0.47
1.1
1.0
1581.60
1471.66
miu/ml
—
10
68
67
590
1.14
0.46
1.1
1.1
1.52
1.52
g/l
0.00
67
590
116
1270
0.91
0.45
1.6
1.7
3.40
3.48
mmol/l
0.45
82
886
32
265
1.21
0.45
1.0
1.1
2.04
3.37
u/ml
0.67
13
141
36
302
1.20
0.44
1.0
1.1
3.06
1.99
u/ml
0.22
16
162
113
1031
1.10
0.44
1.7
2.0
—
—
—
0
0
46
395
1.17
0.44
3.5
3.8
738.68
3628.72
u/ml
0.60
39
349
62
547
1.14
0.42
1.4
1.3
216.22
222.80
miu/ml
0.05
32
267
8
57
1.41
0.42
1.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
2.5
—
0.88
—
0
17
125
1153
1.09
0.40
2.8
2.6
36.28
82.30
u/l
0.56
103
979
17
132
1.29
0.40
1.1
1.1
—
—
—
0
0
8
60
1.34
0.40
1.6
1.8
68.26
104.11
ng/l
—
8
60
5
35
1.43
0.39
1.0
1.1
32.76
43.59
iu/ml
—
5
35
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
9
68
1.33
0.37
1.3
1.2
—
—
—
0
0
27
225
1.20
0.37
1.0
1.0
0.92
0.37
u/ml
—
6
78
15
117
1.29
0.35
3.8
5.2
21.76
94.16
u/ml
—
5
39
290
2778
1.06
0.34
4.1
3.6
1.02
1.02
kg/l
0.07
200
1854
24
286
0.84
0.34
1.5
1.4
858.56
1691.28
e6/l
0.27
18
220
12
155
0.77
0.33
1.3
1.7
—
—
—
0
0
56
502
1.12
0.32
4.0
3.1
1.02
1.02
ratio
0.26
50
470
54
483
1.12
0.32
1.6
1.7
—
—
—
0
0
277
2658
1.05
0.31
4.6
4.0
21.68
21.35
%
0.13
129
1113
7
96
0.73
0.31
3.0
3.9
—
—
—
0
0
7
53
1.32
0.31
1.0
2.8
15.54
174.58
ug/l
—
7
45
7
54
1.30
0.30
1.4
1.1
—
—
—
0
0
131
1230
1.07
0.30
1.9
2.1
—
—
—
0
0
24
282
0.85
0.30
1.5
1.4
12.75
14.71
e6/l
0.07
16
207
7
55
1.27
0.30
2.0
2.1
—
—
—
0
0
7
55
1.27
0.30
2.0
2.1
—
—
—
0
0
987
9986
0.96
0.29
19.7
17.3
13.49
13.45
%
0.40
981
9869
8
106
0.75
0.29
1.0
1.6
9.65
12.10
umol/l
—
8
98
8
107
0.75
0.29
2.0
1.5
—
—
—
0
0
8
107
0.75
0.29
2.0
1.5
—
—
—
0
0
8
107
0.75
0.29
2.0
1.5
—
—
—
0
0
23
195
1.18
0.28
2.9
3.2
7.03
7.38
mmol/l
0.37
23
189
18
216
0.83
0.28
1.3
1.3
—
—
—
0
0
10
129
0.77
0.28
1.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
66
1.21
0.26
1.0
1.2
—
—
—
0
0
10
77
1.30
0.26
1.3
1.2
—
—
—
0
0
18
213
0.84
0.25
1.1
1.1
—
—
—
0
0
13
159
0.82
0.25
1.5
1.3
7.09
7.32
mmol/l
0.11
13
140
6
83
0.72
0.24
1.5
1.4
85.17
76.05
umol/l
—
6
83
13
106
1.23
0.23
1.1
1.3
—
88.20
—
0
5
30
337
0.89
0.22
1.9
1.8
—
—
—
0
0
5
40
1.25
0.22
1.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
8.89
—
0
12
12
98
1.23
0.21
2.0
2.3
—
—
—
0
0
5
43
1.16
0.21
1.8
3.0
—
38.65
—
0
10
6
50
1.20
0.19
1.2
1.1
—
—
—
0
0
15
127
1.18
0.19
2.1
2.3
31.47
32.75
pg
0.32
15
127
18
207
0.87
0.19
1.1
1.1
—
—
—
0
0
73
686
1.07
0.19
13.7
12.8
1.53
1.32
%
1.03
73
681
503
4942
1.03
0.18
1.9
1.9
1.35
1.40
mmol/l
0.62
427
4287
51
549
0.93
0.18
1.5
1.7
4.48
3.68
mg/l
0.34
42
401
40
367
1.09
0.18
1.7
2.1
4.60
3.88
iu/l
0.12
14
156
46
497
0.92
0.18
1.2
1.4
—
—
—
0
0
100
952
1.05
0.18
1.5
1.3
138.87
234.74
u/ml
1.46
94
895
11
91
1.21
0.17
1.2
1.3
5.42
6.29
mmol/l
0.39
11
86
7
63
1.11
0.17
1.7
1.7
—
—
—
0
0
7
63
1.11
0.17
1.7
1.7
—
—
—
0
0
7
63
1.11
0.17
1.7
1.7
—
—
—
0
0
7
63
1.11
0.17
1.7
1.7
—
—
—
0
0
5
66
0.76
0.17
1.4
3.7
1.20
0.89
index
—
5
66
17
194
0.87
0.16
1.1
1.2
—
—
—
0
0
8
69
1.16
0.16
1.9
1.6
0.49
0.50
e9/l
—
8
69
14
120
1.17
0.16
1.1
1.1
—
—
—
0
0
26
235
1.11
0.15
1.3
1.4
22.88
21.45
u/l
0.06
18
199
45
419
1.08
0.15
2.1
2.2
1.47
1.44
g/l
0.09
40
373
6
80
0.75
0.15
1.2
1.2
—
—
—
0
0
6
80
0.75
0.15
1.7
1.2
6.00
8.75
mm/h
—
6
80
14
121
1.16
0.15
1.2
1.1
10.95
16.01
u/ml
—
8
55
7
89
0.79
0.14
3.3
2.0
—
1129.34
—
0
14
14
122
1.15
0.13
1.1
1.1
—
—
—
0
0
207
2018
1.03
0.13
3.2
3.0
0.68
0.72
ug/l
0.38
131
1163
35
326
1.08
0.12
1.4
1.3
—
42.39
—
0
7
20
220
0.91
0.12
1.4
1.4
—
—
—
0
0
10
115
0.87
0.10
2.0
1.7
—
—
—
0
0
11
96
1.15
0.10
1.5
2.5
29.33
32.42
mg/l
—
6
69
24
222
1.08
0.10
1.0
1.0
1.73
2.27
eliau/ml
—
10
104
5
46
1.09
0.09
3.6
2.4
10.92
9.73
mg/l
—
5
39
23
213
1.08
0.09
1.8
1.5
—
—
—
0
0
14
126
1.11
0.09
1.4
1.8
—
—
—
0
0
15
136
1.10
0.08
2.6
3.3
0.85
0.88
nmol/l
0.09
15
112
32
302
1.06
0.08
1.6
2.1
0.00
0.02
g/l
0.50
27
280
23
214
1.08
0.08
1.1
1.1
9.33
117.55
iu/ml
—
9
52
5
62
0.81
0.08
1.0
1.5
—
78.89
—
0
9
8
76
1.05
0.07
1.1
1.4
38.49
37.40
nmol/l
—
8
63
32
304
1.05
0.07
1.5
1.3
180.21
232.85
u/ml
0.93
24
190
7
85
0.82
0.07
1.0
1.8
—
—
—
0
0
37
386
0.96
0.06
1.6
1.7
—
—
—
0
0
33
315
1.05
0.06
1.2
1.2
—
—
—
0
0
33
315
1.05
0.06
1.2
1.2
—
—
—
0
0
21
197
1.07
0.06
1.1
1.1
—
1.57
—
0
12
69
672
1.03
0.05
1.2
1.1
—
1.06
—
0
5
20
188
1.06
0.05
1.3
1.4
—
—
—
0
0
20
188
1.06
0.05
1.3
1.4
—
—
—
0
0
21
221
0.95
0.04
3.1
3.5
25.22
26.28
mg/l
—
9
146
166
1679
0.99
0.04
2.0
1.9
3.48
3.54
ratio
0.27
127
1298
10
109
0.92
0.04
1.0
1.3
—
—
—
0
0
12
129
0.93
0.03
1.7
1.8
—
—
—
0
0
10
108
0.93
0.03
1.0
1.3
—
—
—
0
0
16
152
1.05
0.02
2.0
1.6
68.79
24.79
ng/l
0.81
16
152
11
103
1.07
0.02
1.3
1.3
82.54
162.85
pmol/l
1.95
11
103
11
103
1.07
0.02
1.3
1.1
116.55
109.64
pmol/l
0.10
11
103
17
163
1.04
0.01
1.1
1.1
—
—
—
0
0
23
223
1.03
0.01
6.6
3.0
7.39
8.24
pmol/l
0.16
23
223
30
293
1.02
0.01
1.4
1.3
—
—
—
0
0
96
952
1.01
0.01
8.0
8.0
8.23
8.73
mmol/l
0.37
91
920
78
773
1.01
0.01
1.6
1.6
—
—
—
0
0
29
296
0.98
0.00
1.8
1.6
49.16
56.45
ug/l
0.62
29
296
34
344
0.99
0.00
6.2
4.0
1.42
1.35
mmol/l
0.19
34
336
16
158
1.01
0.00
1.1
1.1
101.06
95.90
%
0.34
16
147
25
248
1.01
0.00
3.1
3.0
1.35
1.55
mmol/l
1.17
25
241
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
29
292
0.99
0.00
3.4
3.7
0.40
0.38
iu/ml
0.15
17
154
29
292
0.99
0.00
1.7
2.1
0.00
0.00
g/l
-0.00
24
261
69
688
1.00
0.00
1.5
1.4
—
—
—
0
0
22
219
1.00
0.00
1.1
1.2
1.43
4.25
u/ml
—
7
73
12
117
1.03
0.00
1.7
1.8
—
—
—
0
0
28
275
1.02
0.00
1.6
1.5
0.24
0.36
nmol/l
1.16
20
228
10
95
1.05
0.00
1.9
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
8.05
—
0
6
5
51
0.98
-0.00
1.2
1.3
147.28
102.82
nmol/l
—
5
38
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
272.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
1.48
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.3
—
401.86
—
0
7
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
9
99
0.91
-0.00
1.9
1.7
—
—
—
0
0
7
73
0.96
-0.00
3.9
8.9
—
58.68
u/ml
—
0
25
5
53
0.94
-0.00
1.2
1.2
—
—
—
0
0
7
69
1.01
-0.00
1.7
1.8
1.84
4.66
nmol/l
—
7
61
0
7
0.00
-0.00
0.0
1.0
—
0.01
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BONE_LONG_LOWER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_LONG_LOWER | 1.158 [0.95, 1.41] | 0.149 |
| Birth year | 0.994 [0.99, 1.0] | 0.166 |
During the follow-up period (1.1.1998 — 31.12.2019), 134 out of 2886 females with CD2_BENIGN_BONE_LONG_LOWER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_LONG_LOWER | 1.061 [0.88, 1.28] | 0.529 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 164 out of 3257 males with CD2_BENIGN_BONE_LONG_LOWER died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BONE_LONG_LOWER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.124% | 0.179% |
| 5 | 0.617% | 1.067% |
| 10 | 1.529% | 2.808% |
| 15 | 3.177% | 5.416% |
| 20 | 5.471% | 9.13% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BONE_LONG_LOWER – Benign neoplasm: Long bones of lower limb
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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