Torticollis

M13_TORTICOLLIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M43.6
  • Hospital discharge: ICD-9 7235
  • Hospital discharge: ICD-8 7172
  • Cause of death: ICD-10 M43.6
  • Cause of death: ICD-9 7235
  • Cause of death: ICD-8 7172

2 out of 7 registries used, show all original rules.

748

4. Check minimum number of events

None

748

5. Include endpoints

None

748

6. Filter based on genotype QC (FinnGen only)

677

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M43
Name in latin
Torticollis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9116 4207 4879
Only index persons 7518 3531 3987
Unadjusted period prevalence (%)
Whole population 0.13 0.12 0.14
Only index persons 0.14 0.13 0.15
Median age at first event (years)
Whole population 10.56 12.33 8.83
Only index persons 12.61 14.72 10.74

-FinnGen-

Key figures

All Female Male
Number of individuals 677 394 283
Unadjusted period prevalence (%) 0.14 0.14 0.13
Median age at first event (years) 25.24 26.58 23.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
700
Matched controls
7000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M43.6
ICD-10 Finland
Torticollis
734.1
307.7
458
18
71720
ICD-8 Finland
Other nonarticular rheumatism, Torticollis not specified as congential, pyschogenic or traumatic
+∞
198.7
181
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
18.6
109.0
90
55
G24.3
ICD-10 Finland
Spasmodic torticollis
28.0
75.8
52
20
7235A
ICD-9 Finland
Other disorders of cervical region, Torticollis, unspecified
+∞
75.4
71
*
M48.0
ICD-10 Finland
Spinal stenosis
23.9
67.4
49
22
N03AX16
ATC
[U] pregabalin
4.7
60.8
172
457
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
12.3
55.8
57
50
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
21.7
54.3
41
20
N03AX12
ATC
[U] gabapentin; oral
5.3
52.3
118
258
N03AE01
ATC
clonazepam; systemic
7.5
51.5
78
115
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
14.5
48.9
45
33
M54.5
ICD-10 Finland
Low back pain
3.2
45.7
261
1093
M54.4
ICD-10 Finland
Lumbago with sciatica
4.5
43.8
121
311
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
5.7
41.9
84
164
M03BX02
ATC
tizanidine; oral
3.0
41.7
470
2821
M03BC01
ATC
orphenadrine (citrate); systemic
3.3
39.8
189
702
N02AX02
ATC
tramadol; systemic, rectal
2.9
39.5
284
1333
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
7.5
36.9
55
79
M54.9
ICD-10 Finland
Dorsalgia, unspecified
4.4
35.4
97
246
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
9.0
34.7
44
52
M54.2
ICD-10 Finland
Cervicalgia
5.0
33.5
76
165
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
52.5
29.6
35
7
M54.3
ICD-10 Finland
Sciatica
7.0
25.7
40
60
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
9.5
24.9
30
33
L01
ICPC
Neck symptom/complaint
2.8
24.0
139
564
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
20.9
20
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
19.9
183
919
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
19.9
19
*
L03
ICPC
Low back symptom/complaint
2.3
19.3
197
1033
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
18.7
272
1635
N06AA09
ATC
amitriptyline; systemic
3.7
18.4
60
171
N02AJ06
ATC
codeine and paracetamol; systemic
2.1
18.3
286
1761
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
18.3
265
1588
N02BF01
ATC
gabapentin; oral
3.6
18.2
64
192
N06AX21
ATC
duloxetine; oral
3.1
17.7
80
281
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
29.7
17.5
23
8
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
16.8
171
889
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.3
16.7
155
776
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.9
16.7
86
325
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
20.7
16.5
24
12
M01AE02
ATC
naproxen; oral, rectal
2.0
16.4
417
3004
R51.80
ICD-10 Finland
Headache
2.4
16.2
134
638
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
25.2
16.1
22
9
M54.6
ICD-10 Finland
Pain in thoracic spine
3.6
15.9
55
163
A02BC02
ATC
pantoprazole; systemic
1.9
15.6
418
3044
G44.2
ICD-10 Finland
Tension-type headache
2.5
15.6
106
461
N02BF02
ATC
pregabalin; oral
4.0
15.3
45
119
A02BC01
ATC
omeprazole; systemic
2.1
14.9
166
890
M03BC51
ATC
orphenadrine, combinations; systemic
2.1
14.9
170
921
M01AB05
ATC
diclofenac; systemic, rectal
1.9
14.8
411
3006
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
14.3
60
201
M79.1
ICD-10 Finland
Myalgia
2.3
14.3
119
566
M47.9
ICD-10 Finland
Spondylosis, unspecified
43.4
14.2
17
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
14.2
180
1013
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
5.9
13.8
25
44
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
76.7
13.6
15
*
R52.9
ICD-10 Finland
Pain, unspecified
2.7
13.5
78
312
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.0
13.4
38
98
M79.6
ICD-10 Finland
Pain in limb
1.8
13.4
281
1864
R25.2
ICD-10 Finland
Cramp and spasm
5.5
12.8
25
47
H02AB06
ATC
prednisolone; systemic
1.8
12.8
292
1982
N06AX11
ATC
mirtazapine; oral
1.9
12.6
220
1372
N05BA01
ATC
diazepam; systemic, rectal
2.4
12.5
90
400
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
12.5
46
142
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
132.3
12.5
13
*
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
12.3
205
1258
AA1AD
NOMESCO Finland
CT of head and brain
2.0
12.3
159
896
R42
ICD-10 Finland
Dizziness and giddiness
2.1
12.2
134
710
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
12.2
141
762
R06.0
ICD-10 Finland
Dyspnoea
2.0
12.1
166
953
N02AA05
ATC
oxycodone; systemic
2.4
12.1
88
393
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
12.0
127
663
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
11.8
272
1838
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.7
11.7
67
267
R07.3
ICD-10 Finland
Other chest pain
2.6
11.5
69
282
M54
ICD-10 Finland
Dorsalgia
2.4
11.4
85
384
C07AA05
ATC
propranolol; systemic
2.0
11.4
151
856
M01AC06
ATC
meloxicam; systemic, rectal
1.9
11.4
193
1187
M54.1
ICD-10 Finland
Radiculopathy
9.8
11.3
22
23
N05BA04
ATC
oxazepam; oral
1.9
11.2
170
1007
M50.3
ICD-10 Finland
Other cervical disc degeneration
20.4
11.2
16
8
M47.82
ICD-10 Finland
Other spondylosis, cervical region
14.2
11.0
18
13
G43.9
ICD-10 Finland
Migraine, unspecified
2.7
11.0
61
239
R03AC02
ATC
salbutamol; inhalant
1.7
10.9
380
2866
M25.5
ICD-10 Finland
Pain in joint
1.8
10.9
212
1358
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
3.5
10.8
37
109
XA402
NOMESCO Finland
ENMG
9.8
10.8
21
22
N06AX16
ATC
venlafaxine; oral
2.2
10.8
105
530
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
10.7
107
546
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
13.2
10.7
18
14
N02BE01
ATC
paracetamol; systemic, rectal
2.0
10.6
585
5021
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
10.4
10
*
A07AA02
ATC
nystatin; oral
3.4
10.4
38
117
N03AX09
ATC
lamotrigine; oral
3.1
10.4
45
154
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
10.4
151
881
R20.2
ICD-10 Finland
Paraesthesia of skin
2.9
10.2
49
178
J01FF01
ATC
clindamycin; systemic
1.8
10.1
170
1038
S80.0
ICD-10 Finland
Contusion of knee
2.5
10.1
66
281
N06AB04
ATC
citalopram; systemic
2.0
9.9
126
701
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.2
9.9
20
39
M01AH05
ATC
etoricoxib; oral
1.7
9.9
373
2845
NF1AA
NOMESCO Finland
Hip X-ray examination
3.0
9.8
44
154
A02BC05
ATC
esomeprazole; systemic
1.7
9.7
226
1516
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
9.6
131
747
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.7
9.5
30
84
SPAT1229
SPAT
Assessment of need for aid
3.2
9.5
37
119
N05AH04
ATC
quetiapine; oral
1.9
9.5
131
750
G43.3
ICD-10 Finland
Complicated migraine
4.3
9.4
24
57
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
9.7
9.3
18
19
J45.1
ICD-10 Finland
Nonallergic asthma
2.6
9.3
53
211
A01
ICPC
Pain general/multiple sites
2.4
9.2
65
286
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
9.2
127
726
B01AA03
ATC
warfarin; systemic
2.2
9.1
80
387
M35.7
ICD-10 Finland
Hypermobility syndrome
10.2
9.1
17
17
R06AE07
ATC
cetirizine; oral
1.6
8.9
298
2187
L28
ICPC
Limited function/disability (L)
2.1
8.8
90
462
TAB00
NOMESCO Finland
Lumbar puncture
3.2
8.8
35
114
M01AH01
ATC
celecoxib; oral
2.2
8.8
81
400
JAH01
NOMESCO Finland
Laparoscopy
3.2
8.8
34
109
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
8.7
124
715
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.9
8.6
41
148
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.4
8.6
31
95
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
8.6
289
2119
W19
ICD-10 Finland
Unspecified fall
2.3
8.4
67
311
R03BA05
ATC
fluticasone; inhalant
1.8
8.4
132
785
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
8.4
55
234
R52.2
ICD-10 Finland
Other chronic pain
3.8
8.4
25
67
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.3
8.4
65
299
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
8.3
8
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.0
8.3
37
129
J01AA02
ATC
doxycycline; systemic
1.6
8.3
458
3768
N05AF03
ATC
chlorprothixene; systemic
3.8
8.2
25
68
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
8.2
159
1006
C03CA01
ATC
furosemide; systemic
1.8
8.2
126
745
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
2.6
8.2
48
194
3007
Kela drug reimbursment
Erenumab and fremanezumab
4.8
8.2
18
38
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.4
8.1
58
257
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
10.2
8.1
15
15
N05CF01
ATC
zopiclone; oral
1.7
8.0
172
1119
T81.9
ICD-10 Finland
Unspecified complication of procedure
4.7
7.9
18
39
UJF32
NOMESCO Finland
Coloscopy
1.8
7.9
125
745
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
8.6
7.8
16
19
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
7.8
135
825
R60.9
ICD-10 Finland
Oedema, unspecified
3.0
7.8
33
112
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
7.8
86
455
N03AG01
ATC
valproic acid; systemic, rectal
2.6
7.7
43
169
3AX01, ,
NOMESCO Finland
15.2
7.7
12
8
R53
ICD-10 Finland
Malaise and fatigue
1.7
7.7
166
1080
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.9
7.7
36
129
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
7.7
99
552
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.6
7.6
44
176
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.2
7.6
67
324
J01DA01
ATC
[U] cefalexin
1.6
7.6
379
3018
S18
ICPC
Laceration/cut
1.6
7.5
273
2021
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
7.5
308
2345
N06AX03
ATC
mianserin; oral
3.0
7.5
32
109
X57
ICD-10 Finland
Unspecified privation
4.5
7.5
18
41
3338X
ICD-9 Finland
Other extrapyramidal disease and abnormal movement disorders, Fragments of torsion dystonia
80.9
7.4
8
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
7.4
82
433
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.4
7.4
49
210
A01AB04
ATC
amphotericin B; local oral
3.5
7.3
25
74
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
7.2
115
685
L86
ICPC
Back syndrome with radiating pain
3.3
7.2
27
85
M54.8
ICD-10 Finland
Other dorsalgia
3.5
7.2
24
70
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
30.3
7.2
9
*
R52.1
ICD-10 Finland
Chronic intractable pain
20.3
7.1
10
5
K30
ICD-10 Finland
Functional dyspepsia
2.1
7.1
71
361
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
7.1
246
1796
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
4.1
7.1
19
47
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.7
7.1
37
141
U07
ICPC
Urine symptom/complaint other
2.3
7.0
51
228
R96
ICPC
Asthma
2.2
7.0
59
281
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
6.9
128
797
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.9
358
2853
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
6.9
71
366
C07AB07
ATC
bisoprolol; oral
1.6
6.9
228
1647
R50.9
ICD-10 Finland
Fever, unspecified
1.8
6.8
103
604
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.3
6.7
15
21
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
6.7
80
434
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.7
133
844
G24.8
ICD-10 Finland
Other dystonia
22.8
6.7
9
*
R06AX11
ATC
astemizole; oral
3.1
6.7
27
89
J45
ICD-10 Finland
Asthma
2.1
6.7
67
342
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.7
6.6
36
140
A02BC03
ATC
lansoprazole; oral
1.7
6.6
137
879
N04BC05
ATC
pramipexole; oral
2.6
6.6
38
152
M13.9
ICD-10 Finland
Arthritis, unspecified
2.4
6.6
47
208
L17
ICPC
Foot/toe symptom/complaint
1.6
6.6
188
1308
F01
ICPC
Eye pain
2.9
6.6
30
106
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
3.9
6.6
19
50
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
6.5
84
468
N02CC04
ATC
rizatriptan; oral
2.4
6.5
45
197
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.9
6.5
87
491
M03AX01
ATC
botulinum toxin; parenteral
4.0
6.5
18
46
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
6.5
60
297
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.6
6.5
37
148
S89.9
ICD-10 Finland
Unspecified injury of lower leg
2.8
6.5
31
113
M53.2
ICD-10 Finland
Spinal instabilities
70.5
6.4
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
6.4
143
935
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
14.5
6.4
10
7
UJF92
NOMESCO Finland
Capsular endoscopy
3.8
6.4
19
51
R55
ICD-10 Finland
Syncope and collapse
2.1
6.4
60
299
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.6
6.3
167
1140
M45
ICD-10 Finland
Ankylosing spondylitis
18.2
6.3
9
5
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
+∞
6.3
6
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.7
6.2
19
52
N89
ICPC
Migraine
2.5
6.2
39
163
L12
ICPC
Hand/finger symptom/complaint
1.7
6.2
116
723
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
2.5
6.2
37
151
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.6
6.2
35
139
R05
ICPC
Cough
1.6
6.2
165
1128
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
12.7
6.1
10
8
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
3.2
6.1
24
78
G47.3
ICD-10 Finland
Sleep apnoea
1.7
6.1
129
833
M22.4
ICD-10 Finland
Chondromalacia patellae
3.2
6.1
23
73
R4110
NOMESCO Finland
Physiotherapy
1.6
6.0
151
1016
K59.0
ICD-10 Finland
Constipation
2.6
6.0
33
129
R03DC03
ATC
montelukast; oral
1.7
6.0
106
650
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.9
6.0
77
428
R02
ICPC
Shortness of breath/dyspnoea
1.9
6.0
74
406
M02AA07
ATC
piroxicam; topical
1.6
6.0
166
1144

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
403
3047
1.76
11.85
6.2
4.8
6.53
6.61
mmol/l
0.28
393
2831
361
2646
1.75
11.84
7.0
6.5
10.02
11.95
umol/l
3.40
345
2523
260
1743
1.78
11.58
3.9
3.1
18.63
60.00
ng/l
1.11
155
1059
297
2076
1.75
11.39
18.9
10.1
1.26
1.17
inr
1.73
254
1723
301
2120
1.74
11.18
4.8
5.0
37.26
36.59
g/l
1.29
279
2006
495
4010
1.80
11.09
9.1
7.4
80.54
78.96
u/l
0.28
484
3809
393
2987
1.72
11.00
8.3
6.1
2.10
1.97
e9/l
0.83
356
2656
384
2916
1.70
10.65
8.3
6.1
0.59
0.56
e9/l
0.96
338
2527
267
1840
1.73
10.58
7.3
6.2
—
—
—
0
0
383
2916
1.69
10.43
8.4
6.1
0.04
0.04
e9/l
0.10
335
2533
331
2432
1.68
10.26
8.3
7.3
1.21
1.21
mmol/l
0.48
297
2133
416
3249
1.69
10.19
11.4
9.6
4.17
3.98
e9/l
0.66
363
2822
212
1383
1.76
10.11
2.9
2.0
155.82
207.30
u/l
0.92
207
1317
391
3011
1.68
10.05
8.6
6.5
0.19
0.18
e9/l
0.32
354
2651
196
1258
1.78
9.85
2.1
2.6
326.41
338.17
umol/l
0.92
172
1153
229
1541
1.72
9.72
2.9
2.4
50.62
63.08
u/l
2.30
221
1439
297
2148
1.66
9.58
8.8
6.8
1.21
1.21
mmol/l
1.51
276
2015
358
2740
1.63
9.06
7.8
6.1
56.13
56.31
%
0.10
338
2637
190
1242
1.73
8.82
4.2
4.1
—
—
—
0
0
67
306
2.32
8.75
4.7
2.9
—
—
—
0
0
360
2793
1.59
8.37
7.8
6.2
29.45
29.07
%
0.26
340
2676
287
2110
1.61
8.37
2.2
1.8
91.68
97.69
pmol/l
1.40
165
1136
91
479
2.03
8.33
5.9
4.5
1.72
1.54
mmol/l
0.17
80
395
350
2703
1.59
8.26
7.8
6.2
2.74
2.81
%
0.27
325
2556
187
1237
1.70
8.24
4.3
3.2
—
0.15
—
0
13
164
1047
1.74
8.22
2.9
2.5
6.94
7.35
e6/l
0.10
149
948
350
2707
1.59
8.18
7.8
6.3
8.46
8.70
%
1.02
328
2563
349
2698
1.59
8.17
7.9
6.3
0.68
0.68
%
0.05
326
2545
228
1592
1.64
8.15
3.8
3.0
299.60
100.61
e6/l
0.38
175
1176
313
2361
1.59
8.12
3.9
2.9
6.25
6.20
ph
0.35
178
1350
93
498
2.00
8.11
5.9
4.4
7.38
7.38
ph
0.04
50
300
176
1154
1.70
7.98
3.4
3.3
1242.14
1123.36
ng/l
0.11
141
968
266
1938
1.60
7.95
4.2
3.5
78.11
113.95
e6/l
0.45
186
1274
374
2950
1.58
7.94
4.1
3.2
0.00
5.26
estimate
0.79
80
631
200
1361
1.66
7.87
3.8
2.9
0.24
0.37
e6/l
0.88
149
959
113
661
1.85
7.56
1.7
1.6
1097.04
1136.19
nmol/l
0.16
91
505
139
868
1.75
7.47
1.3
1.2
7.89
10.75
u/ml
0.22
67
350
368
2928
1.54
7.27
4.2
3.2
0.00
0.00
estimate
0.50
84
633
452
3767
1.56
7.21
4.9
3.8
—
2.86
—
0
7
324
2512
1.54
7.17
3.6
2.6
—
—
estimate
—
0
0
371
2963
1.54
7.16
4.3
3.3
0.01
0.01
estimate
0.02
77
584
148
953
1.70
7.10
1.3
1.3
31.72
29.13
iu/ml
0.06
39
282
425
3500
1.55
7.10
5.7
3.8
14662.65
478.00
e6/l
—
6
46
130
808
1.75
7.08
2.7
2.4
13.27
13.82
umol/l
0.35
117
758
235
1716
1.56
6.72
3.4
2.1
—
—
—
0
0
186
1288
1.60
6.68
3.5
2.1
—
—
—
0
0
194
1357
1.59
6.67
2.5
2.1
2.60
2.79
mg/l
0.56
168
1163
185
1280
1.61
6.66
4.2
3.2
1.02
1.02
kg/l
0.04
121
827
127
800
1.72
6.57
1.5
1.4
433.10
472.28
titre
0.12
29
171
201
1425
1.58
6.51
3.6
2.5
—
—
—
0
0
85
480
1.88
6.33
7.7
9.7
5.20
5.15
kpa
0.18
80
466
85
480
1.88
6.33
7.7
9.7
12.44
12.78
kpa
0.25
80
466
135
876
1.67
6.24
4.4
3.1
464.52
624.99
ng/l
0.25
91
594
41
176
2.41
6.19
2.0
1.6
0.22
0.24
g/l
0.81
36
166
628
5756
1.89
6.16
18.8
11.8
21.10
22.62
mg/l
0.59
543
4532
187
1321
1.57
6.10
1.9
1.6
20.24
20.19
nmol/l
0.01
162
1137
313
2474
1.48
5.97
2.7
2.4
74.85
73.53
nmol/l
0.33
288
2302
110
684
1.72
5.94
2.9
2.5
22.61
23.40
%
0.20
100
645
238
1782
1.51
5.92
3.2
3.6
8.14
8.29
mmol/l
0.16
208
1550
329
2630
1.47
5.91
10.9
9.9
0.00
0.00
e9/l
0.62
273
2140
119
758
1.69
5.88
2.8
2.4
2.45
2.36
g/l
1.02
111
704
84
484
1.84
5.87
7.6
9.7
0.77
0.89
mmol/l
0.08
71
407
84
486
1.83
5.79
7.8
9.7
7.42
7.41
ph
0.18
39
272
41
182
2.33
5.76
2.0
1.6
1.17
1.19
g/l
0.15
36
172
34
140
2.50
5.62
1.6
1.3
360.26
288.15
ug/g
1.00
22
83
193
1405
1.52
5.41
5.3
4.0
7.40
7.40
ph
0.01
134
985
45
216
2.16
5.27
1.0
1.1
—
—
—
0
0
163
1153
1.54
5.20
2.1
1.8
0.72
1.09
mg/l
1.98
117
875
285
2256
1.44
5.19
4.1
3.1
0.01
0.03
estimate
0.50
73
530
254
1969
1.46
5.16
3.2
3.4
31.89
31.92
u/l
0.00
246
1875
207
1551
1.48
4.98
1.5
1.4
2.27
1.76
u/ml
0.16
62
417
208
1560
1.47
4.98
4.4
3.3
0.00
0.01
estimate
0.88
72
600
18
56
3.27
4.92
1.2
1.5
—
—
—
0
0
29
119
2.50
4.85
1.1
1.3
3.99
3.66
mmol/l
0.64
29
113
40
190
2.17
4.83
1.3
1.2
—
—
—
0
0
100
643
1.65
4.75
4.2
3.7
3.99
4.42
e9/l
0.66
88
582
75
446
1.76
4.73
10.3
10.6
—
—
—
0
0
116
778
1.59
4.64
3.5
2.8
4.00
3.64
e6/l
0.12
54
361
123
838
1.57
4.60
3.2
2.6
158.70
115.83
ug/g
0.74
104
666
510
4542
1.45
4.56
4.7
4.1
14.59
14.54
pmol/l
0.19
467
4216
136
950
1.54
4.55
2.9
2.7
533.95
541.15
mosm/kgh2o
0.12
118
825
73
436
1.75
4.54
2.0
2.1
—
—
—
0
0
60
338
1.85
4.53
2.0
2.8
—
—
—
0
0
219
1690
1.43
4.43
3.0
3.4
2.36
2.36
mmol/l
0.29
191
1563
61
349
1.82
4.39
2.7
2.2
28.65
20.07
au/ml
—
10
36
39
195
2.06
4.16
1.7
2.6
—
—
—
0
0
76
472
1.68
4.12
2.0
2.1
—
—
—
0
0
76
473
1.68
4.09
1.7
2.1
—
—
—
0
0
76
475
1.67
4.03
2.0
2.1
—
—
—
0
0
609
5665
1.58
4.00
20.1
13.5
139.62
139.62
mmol/l
0.02
601
5546
610
5678
1.58
3.98
20.4
13.6
3.95
3.94
mmol/l
0.31
601
5538
78
493
1.66
3.97
2.7
2.2
31.89
41.22
u/l
0.48
66
424
75
474
1.65
3.82
2.0
2.0
—
—
—
0
0
29
134
2.21
3.78
1.2
1.4
554.07
474.82
mg/l
0.28
29
129
24
102
2.40
3.78
1.8
1.2
—
—
—
0
0
42
224
1.93
3.77
3.9
4.6
—
—
—
0
0
25
109
2.34
3.73
1.3
1.5
—
—
—
0
0
580
5363
1.48
3.68
5.8
4.9
1.77
1.84
mu/l
0.97
544
5045
60
362
1.72
3.63
2.1
2.1
—
—
—
0
0
647
6135
1.72
3.61
21.4
14.7
74.76
73.24
umol/l
0.32
640
6067
93
630
1.55
3.56
1.3
1.2
—
—
—
0
0
66
415
1.65
3.44
3.3
4.4
7.37
7.34
ph
0.45
50
309
101
709
1.50
3.29
2.0
1.9
—
—
—
0
0
571
5303
1.42
3.17
4.9
4.1
5.88
5.80
mmol/l
0.64
532
4928
41
232
1.81
3.11
2.2
2.0
4.48
8.39
iu/ml
0.58
13
50
90
624
1.51
3.11
1.8
1.5
—
—
—
0
0
15
56
2.72
3.07
1.5
1.6
—
—
—
0
0
639
6077
1.59
3.04
15.1
10.7
—
—
—
0
0
24
113
2.16
3.03
1.3
1.4
6.39
17.05
e6/l
0.55
18
83
24
114
2.14
2.97
1.3
1.5
20.74
802.63
e6/l
0.61
19
87
463
4183
1.32
2.94
3.6
3.1
44.15
41.60
u/l
0.32
448
4000
32
172
1.90
2.86
1.2
1.1
3.47
9.23
eliau/ml
—
8
29
84
585
1.50
2.85
1.5
1.4
—
—
—
0
0
31
165
1.92
2.85
1.6
1.9
0.54
3.08
ug/l
0.88
23
150
29
153
1.93
2.74
8.1
5.7
—
—
—
0
0
104
763
1.43
2.71
3.3
2.2
29.33
29.47
s
0.09
104
747
201
1640
1.32
2.68
6.9
5.9
—
—
—
0
0
74
509
1.51
2.67
5.0
3.1
1.67
1.75
%
0.25
66
459
65
436
1.54
2.64
3.7
4.8
0.47
0.64
%
0.25
17
121
340
2978
1.28
2.61
3.8
3.0
103.41
97.13
ug/l
0.29
318
2812
192
1563
1.31
2.60
3.8
3.0
—
0.83
—
0
6
65
438
1.53
2.59
3.6
4.9
0.19
0.14
%
0.12
16
113
76
530
1.49
2.58
1.3
1.2
—
—
—
0
0
114
858
1.39
2.57
3.2
2.7
2.43
2.43
mmol/l
0.04
94
778
48
302
1.63
2.55
2.9
2.2
6.78
8.97
ug/l
0.45
41
274
172
1383
1.32
2.53
1.6
1.5
2.11
2.22
g/l
0.41
109
878
47
295
1.64
2.52
1.4
1.2
—
—
—
0
0
176
1424
1.32
2.48
5.6
4.5
—
—
—
0
0
7
16
4.41
2.48
3.3
1.3
350.71
84.75
nmol/24h
—
7
16
127
979
1.36
2.47
1.6
1.6
417.32
36461229.61
pmol/l
1.22
111
842
67
460
1.50
2.45
3.5
4.8
0.67
1.04
%
0.86
18
135
672
6516
1.78
2.39
27.7
18.4
263.11
254.36
e9/l
3.01
667
6385
49
317
1.59
2.34
1.8
1.5
0.32
0.31
mg/l
0.08
27
154
672
6522
1.76
2.29
27.7
18.4
4.57
4.58
e12/l
0.17
663
6379
8
23
3.51
2.27
1.1
1.3
139.00
140.83
nmol/l
—
8
23
93
692
1.40
2.25
1.6
1.8
—
—
—
0
0
199
1656
1.28
2.25
3.1
2.6
0.00
0.00
—
7
29
672
6525
1.75
2.24
27.7
18.4
7.06
6.68
e9/l
4.39
663
6376
637
6114
1.47
2.22
13.6
9.8
27.43
26.84
u/l
0.38
628
5965
24
129
1.89
2.19
1.2
1.1
6.02
24.51
au/ml
—
6
36
178
1466
1.29
2.18
3.6
3.7
46.03
60.30
mg/l
0.39
111
983
14
61
2.32
2.16
1.2
1.1
17.45
15.01
u/ml
—
6
34
12
49
2.47
2.11
1.2
1.1
—
—
—
0
0
26
146
1.81
2.09
1.4
1.1
—
—
—
0
0
66
470
1.45
2.05
2.1
2.6
0.24
0.22
g/l
1.20
61
444
32
193
1.69
2.03
2.2
2.3
—
—
—
0
0
54
370
1.50
2.03
5.6
3.2
71.56
70.47
e9/l
0.07
38
256
81
600
1.40
2.02
3.2
3.2
5.05
6.81
umol/l
1.45
72
524
36
225
1.63
2.00
3.6
3.1
1.02
1.02
ratio
0.27
31
203
58
406
1.47
1.97
3.6
5.3
2.71
17.91
ug/l
0.81
44
328
58
407
1.46
1.95
1.4
1.5
20.52
23.14
iu/l
0.32
51
346
5
11
4.57
1.94
3.0
2.5
—
—
—
0
0
5
11
4.57
1.94
1.4
1.0
—
—
—
0
0
5
11
4.57
1.94
1.4
1.0
10.92
5.36
mg/g
—
5
11
6
16
3.77
1.94
1.0
1.1
—
469.00
—
0
7
11
45
2.47
1.93
1.2
1.1
280.00
232.51
mg/l
0.21
11
39
546
5151
1.27
1.90
5.9
5.2
38.44
38.23
mmol/mol
0.23
517
4892
42
277
1.55
1.89
2.9
1.8
—
—
—
0
0
6
17
3.55
1.84
1.2
1.2
31.33
26.12
s
—
6
17
7
23
3.06
1.80
3.7
2.1
14.83
16.93
umol/l
—
7
23
33
208
1.62
1.80
1.9
1.7
17.72
8.27
u/ml
—
5
62
8
29
2.78
1.79
1.3
1.0
—
—
—
0
0
11
47
2.36
1.78
1.4
1.1
41.82
51.64
mg/l
0.25
11
35
61
441
1.42
1.77
4.0
5.3
0.00
0.19
%
1.44
14
104
19
103
1.87
1.73
1.3
2.5
134.17
129.98
g/l
0.28
12
92
61
444
1.41
1.71
2.2
1.9
0.00
0.05
estimate
0.78
15
110
178
1507
1.24
1.71
4.2
4.4
6.97
8.75
mg/mmol
0.29
111
983
20
112
1.81
1.66
4.6
3.8
—
—
—
0
0
19
106
1.81
1.60
1.2
1.1
1.24
2.75
eliau/ml
1.41
11
54
6
20
3.02
1.58
1.2
1.1
—
—
—
0
0
7
26
2.71
1.58
1.3
1.1
393.71
208.32
iu/ml
—
7
26
5
15
3.35
1.52
2.8
1.9
—
—
—
0
0
199
1726
1.21
1.50
3.1
2.8
0.00
0.01
estimate
1.71
68
505
112
915
1.27
1.46
1.6
1.7
—
—
—
0
0
21
126
1.69
1.41
1.3
2.3
—
17.20
—
0
5
9
40
2.27
1.40
3.9
4.0
667.89
619.85
u/ml
—
9
40
10
46
2.19
1.40
1.3
1.1
—
—
—
0
0
5
17
2.95
1.36
2.8
1.9
—
—
—
0
0
51
679
0.73
1.35
1.3
1.7
3.56
3.42
mmol/l
0.28
30
471
31
208
1.51
1.35
2.9
4.6
240.83
316.95
mg/l
0.37
12
110
18
105
1.73
1.34
1.3
1.2
4.00
3.89
u/ml
—
7
54
10
47
2.14
1.34
3.2
2.4
—
—
—
0
0
583
5617
1.23
1.23
4.8
4.3
4.64
4.65
mmol/l
0.15
555
5329
28
188
1.51
1.23
1.4
1.3
—
—
—
0
0
238
2133
1.18
1.23
2.3
2.0
—
—
—
0
0
587
5662
1.23
1.21
5.3
4.8
2.77
2.77
mmol/l
0.01
557
5355
78
626
1.28
1.20
1.4
1.4
—
—
—
0
0
83
672
1.27
1.19
1.2
1.2
—
—
—
0
0
580
5592
1.22
1.17
4.7
4.3
1.39
1.45
mmol/l
3.21
550
5281
61
477
1.31
1.15
1.2
1.3
52.03
154.04
u/ml
5.63
28
195
17
103
1.67
1.13
1.4
1.1
—
—
—
0
0
241
2654
0.86
1.12
2.7
2.8
—
—
—
0
0
124
1060
1.21
1.09
1.9
1.8
—
—
—
0
0
5
21
2.39
1.09
2.0
1.1
7.47
7.43
ph
—
5
13
8
41
1.96
1.09
1.1
1.1
—
—
—
0
0
13
74
1.77
1.07
1.3
1.4
—
—
—
0
0
13
74
1.77
1.07
1.3
1.4
—
—
—
0
0
13
74
1.77
1.07
1.3
1.4
—
—
—
0
0
13
74
1.77
1.07
1.3
1.4
—
—
—
0
0
7
33
2.13
1.05
1.7
2.4
147.29
139.67
e6/l
—
7
33
34
246
1.40
1.05
2.9
2.4
—
—
—
0
0
551
5303
1.18
1.05
4.1
3.7
1.36
1.25
mmol/l
2.19
526
4984
5
22
2.28
1.03
1.0
1.1
142.80
166.55
mmol/24h
—
5
22
13
77
1.70
0.95
2.4
2.2
—
—
—
0
0
19
126
1.52
0.92
1.0
1.1
—
—
—
0
0
156
1383
1.16
0.91
1.9
1.8
—
—
—
0
0
13
79
1.66
0.88
1.5
1.6
—
—
—
0
0
8
43
1.87
0.87
2.1
1.3
—
—
—
0
0
6
30
2.01
0.87
1.8
1.1
—
—
—
0
0
53
425
1.27
0.86
3.3
2.3
6.00
6.13
ph
0.65
36
276
20
137
1.47
0.85
3.8
3.1
61.20
57.02
%
0.75
20
137
6
31
1.94
0.84
2.2
1.6
—
—
—
0
0
8
45
1.79
0.84
2.1
1.5
0.56
0.49
e9/l
—
8
45
67
801
0.82
0.82
1.2
1.3
—
—
—
0
0
21
148
1.43
0.78
1.1
1.1
1.05
5.57
u/ml
1.58
13
77
6
34
1.77
0.76
1.8
1.2
—
—
—
0
0
10
59
1.70
0.76
1.2
1.4
1.03
3.88
u/ml
—
5
31
5
25
2.01
0.73
3.2
3.9
14.28
16.38
%
—
5
25
7
39
1.80
0.72
1.4
1.1
—
—
—
0
0
13
84
1.56
0.72
4.5
4.5
668.54
525.04
u/ml
0.09
13
79
7
40
1.76
0.71
1.1
1.2
—
—
—
0
0
9
58
1.56
0.70
6.6
3.3
13.06
11.14
%
—
9
58
9
58
1.56
0.70
1.1
1.3
—
—
—
0
0
186
1702
1.13
0.70
2.2
2.1
—
—
—
0
0
19
135
1.42
0.69
1.9
3.3
2.55
2.64
index
0.02
11
71
11
69
1.60
0.68
1.3
1.8
—
—
—
0
0
11
69
1.60
0.68
1.3
1.2
—
—
—
0
0
7
42
1.67
0.68
1.1
1.0
1576.43
1405.50
miu/ml
—
7
42
45
366
1.25
0.68
4.1
3.7
4.27
4.73
pmol/l
2.36
40
334
15
102
1.48
0.68
2.1
2.4
34.50
133.75
ug/min
—
8
61
17
119
1.44
0.67
1.4
1.7
—
—
—
0
0
7
43
1.63
0.67
1.9
1.1
14.86
8.37
mm/h
—
7
43
32
250
1.29
0.67
2.3
1.9
0.00
0.01
estimate
—
10
87
7
44
1.60
0.65
4.9
2.3
—
—
—
0
0
7
44
1.60
0.65
1.3
1.5
—
—
nmol/l
—
0
0
7
44
1.60
0.65
1.1
1.1
—
—
—
0
0
13
87
1.50
0.63
1.2
1.1
—
—
—
0
0
5
30
1.67
0.61
1.0
1.4
—
—
—
0
0
13
89
1.47
0.58
1.2
1.2
—
—
—
0
0
26
202
1.30
0.58
1.5
1.2
—
—
—
0
0
34
276
1.24
0.55
6.1
4.9
—
—
—
0
0
9
60
1.51
0.54
1.1
1.3
0.43
0.38
g/l
—
9
45
9
60
1.51
0.54
1.1
1.3
2.67
2.88
g/l
—
9
45
9
60
1.51
0.54
1.1
1.3
6.08
6.46
g/l
—
9
45
15
108
1.40
0.53
1.7
1.5
10319.44
14122.07
e6/l
—
9
74
28
223
1.27
0.53
2.2
1.7
—
—
—
0
0
6
40
1.50
0.51
1.3
1.6
—
—
—
0
0
14
101
1.39
0.50
4.9
3.4
3.88
4.00
e9/l
0.10
14
101
77
684
1.14
0.48
8.7
6.8
1.06
1.08
mmol/l
0.13
70
636
147
1360
1.10
0.47
4.1
4.3
1.72
2.09
ug/l
0.55
136
1237
202
1900
1.09
0.45
1.7
1.6
—
—
—
0
0
7
51
1.38
0.44
4.0
1.9
2.70
0.64
mmol/l
—
7
51
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
15
194
0.77
0.41
1.1
1.3
—
504.00
—
0
5
0
17
0.00
0.40
0.0
1.1
—
14.99
—
0
12
0
17
0.00
0.40
0.0
1.5
—
1308.00
—
0
10
48
419
1.16
0.40
1.4
1.5
—
—
—
0
0
5
36
1.39
0.38
2.8
2.4
—
—
—
0
0
46
402
1.15
0.38
2.2
2.3
9260.88
5718.83
u/l
0.29
15
176
6
42
1.43
0.35
1.0
1.2
71.50
78.52
umol/l
—
6
42
11
82
1.35
0.34
1.5
1.3
—
—
—
0
0
40
352
1.14
0.31
1.8
1.7
277.94
300.20
mu/l
0.23
33
321
7
52
1.35
0.31
1.0
1.1
—
—
—
0
0
17
138
1.24
0.30
1.1
1.1
2.53
6.76
u/ml
—
10
69
7
54
1.30
0.30
1.6
1.3
147.41
162.76
pmol/l
—
7
54
40
354
1.14
0.29
1.1
1.2
—
—
—
0
0
24
204
1.18
0.29
1.2
1.2
6.57
3.96
u/ml
0.20
16
115
16
130
1.24
0.29
1.1
1.0
0.13
0.45
u/ml
—
9
47
40
355
1.13
0.29
1.2
1.1
—
—
—
0
0
70
644
1.10
0.28
1.3
1.4
—
—
—
0
0
29
256
1.14
0.23
1.7
1.8
39.28
36.86
nmol/l
0.31
29
248
5
38
1.32
0.23
5.0
3.0
—
—
—
0
0
7
94
0.74
0.22
8.1
3.2
16.26
7.41
pmol/l
—
7
94
21
182
1.16
0.21
1.2
1.1
1.98
2.56
u/ml
0.16
13
108
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
12.12
—
0
10
0
12
0.00
0.21
0.0
1.3
—
9.22
—
0
12
28
314
0.89
0.21
1.6
1.6
62.08
60.06
ug/l
0.06
20
269
5
43
1.16
0.21
1.0
1.2
118.80
113.53
pmol/l
—
5
43
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
49
1.23
0.20
1.2
1.2
—
—
—
0
0
7
59
1.19
0.18
1.7
2.1
43.76
39.59
%
—
7
59
59
552
1.08
0.18
2.2
2.3
13.31
13.15
nmol/l
0.05
53
520
22
195
1.13
0.17
1.2
1.1
—
—
—
0
0
21
186
1.13
0.17
1.3
1.3
—
—
—
0
0
50
466
1.08
0.17
3.9
3.4
—
—
—
0
0
8
70
1.14
0.16
1.8
2.0
—
—
—
0
0
52
555
0.93
0.16
1.5
1.6
906.76
974.24
mu/l
0.27
37
477
64
604
1.07
0.16
1.4
1.6
—
—
—
0
0
15
130
1.16
0.15
2.2
2.5
—
—
—
0
0
15
131
1.15
0.14
1.5
3.1
2.67
9.24
umol/l
—
6
101
34
315
1.08
0.13
1.4
1.3
—
—
—
0
0
21
191
1.10
0.12
1.4
2.0
2.28
4.49
iu/l
—
8
77
234
2296
1.03
0.11
1.9
1.9
1.53
1.35
mmol/l
1.19
205
2005
99
1014
0.97
0.07
1.5
1.5
—
—
—
0
0
38
364
1.05
0.06
4.6
3.5
1.21
1.23
mmol/l
0.67
33
313
23
244
0.94
0.06
1.6
1.5
—
—
—
0
0
9
103
0.87
0.06
1.0
1.3
—
—
—
0
0
28
266
1.05
0.06
1.5
1.6
6.93
8.38
u/l
0.61
22
218
17
158
1.08
0.06
2.0
1.5
—
—
—
0
0
13
120
1.08
0.05
1.2
1.1
—
—
—
0
0
13
120
1.08
0.05
1.0
1.0
—
—
—
0
0
37
383
0.96
0.04
1.5
1.5
—
—
—
0
0
31
322
0.96
0.04
1.0
1.1
0.90
0.90
g/l
0.01
31
322
20
190
1.05
0.04
1.2
1.1
9.51
5.22
u/ml
0.23
11
122
85
839
1.01
0.02
2.7
2.6
0.60
0.75
ug/l
0.98
48
453
10
93
1.08
0.02
1.1
1.1
1.36
1.43
g/l
—
10
85
30
308
0.97
0.02
1.2
1.4
257.46
259.97
miu/ml
0.01
17
151
31
318
0.97
0.02
1.0
1.1
1.51
1.51
g/l
0.04
31
318
19
183
1.04
0.01
1.2
1.1
0.51
1.94
u/ml
1.01
11
92
18
174
1.04
0.00
1.7
1.3
329.00
243.24
u/ml
0.66
13
101
11
115
0.96
0.00
1.0
1.1
—
—
—
0
0
14
136
1.03
0.00
1.1
1.5
2.88
2.92
ug/l
0.01
14
124
17
174
0.98
0.00
1.1
1.1
—
—
—
0
0
17
174
0.98
0.00
1.1
1.1
—
—
—
0
0
13
127
1.02
0.00
1.4
1.3
—
—
—
0
0
24
238
1.01
0.00
1.6
1.5
1.27
1.27
mm
0.01
14
180
25
248
1.01
0.00
1.6
1.6
—
—
—
0
0
10
101
0.99
0.00
1.4
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
365.13
—
0
8
0
8
0.00
0.00
0.0
1.1
—
63.76
—
0
8
0
6
0.00
-0.00
0.0
2.8
—
7.00
—
0
6
9
94
0.96
-0.00
4.1
3.8
—
—
—
0
0
7
71
0.99
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
30.40
—
0
5
6
60
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
3.70
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.87
—
0
5
0
5
0.00
-0.00
0.0
2.4
—
31.00
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
62
0.97
-0.00
1.3
1.3
—
—
—
0
0
6
62
0.97
-0.00
1.8
2.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
6.9
—
0.40
—
0
9

Mortality – FinRegistry

Association

Association between endpoint M13_TORTICOLLIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_TORTICOLLIS 1.139 [0.93, 1.4] 0.219
Birth year 0.997 [0.99, 1.01] 0.44

During the follow-up period (1.1.1998 — 31.12.2019), 127 out of 2594 females with M13_TORTICOLLIS died.

Males

Parameter HR [95% CI] p-value
M13_TORTICOLLIS 1.233 [1.0, 1.51] 0.045
Birth year 0.983 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 149 out of 3021 males with M13_TORTICOLLIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_TORTICOLLIS.

N-year risk Females Males
1 0.114% 0.207%
5 0.744% 1.233%
10 1.772% 3.16%
15 3.443% 5.849%
20 6.289% 9.76%

Relationships between endpoints

Index endpoint: M13_TORTICOLLIS – Torticollis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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