subacute thyroiditis: Spontaneously remitting inflammatory condition of the THYROID GLAND, characterized by FEVER; MUSCLE WEAKNESS; SORE THROAT; severe thyroid PAIN; and an enlarged damaged gland containing GIANT CELLS. The disease frequently follows a viral infection.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1614 |
4. Check minimum number of eventsNone |
1614 |
5. Include endpointsNone |
1614 |
6. Filter based on genotype QC (FinnGen only) |
1459 |
Control definitions (FinnGen only)
- Control exclude
- E4_THYROID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF10
- Parent code in ICD-10
- E06
- Name in latin
- Thyreoiditis subacuta
Similar endpoints
↥List of similar endpoints to
Subacute thyroiditis
based on the number of shared cases.
Similar with more cases:
- Thyroiditis
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8817 | 6740 | 2008 |
| Only index persons | 8221 | 6380 | 1841 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.19 | 0.06 |
| Only index persons | 0.20 | 0.23 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 48.24 | 47.71 | 50.24 |
| Only index persons | 47.78 | 47.28 | 49.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1459 | 1209 | 250 |
| Unadjusted period prevalence (%) | 0.38 | 0.43 | 0.11 |
| Median age at first event (years) | 48.49 | 48.08 | 50.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1515
- Matched controls
- 15150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
99.6
307.7
316
40
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
307.7
1269
*
H03AA01
ATC
levothyroxine sodium; systemic
49.4
307.7
586
191
H03BB01
ATC
carbimazole; oral
137.9
275.0
138
11
E03
ICD-10 Finland
Other hypothyroidism
110.2
255.3
131
13
T86
ICPC
Hypothyroidism/myxoedema
71.5
173.0
94
14
E03.89
ICD-10 Finland
Other specified hypothyroidism
94.5
170.3
89
10
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
50.6
164.0
95
20
104
Kela drug reimbursment
Thyroid insufficiency
342.6
153.8
153
5
H02AB06
ATC
prednisolone; systemic
4.2
147.2
1056
5403
2451A
ICD-9 Finland
Thyroiditis, Subacute thyroiditis
+∞
136.6
129
*
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
26.1
110.3
77
31
E06.9
ICD-10 Finland
Thyroiditis, unspecified
230.0
105.0
107
5
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
279.2
103.2
104
*
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
876.0
85.5
83
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.6
84.7
171
334
24500
ICD-8 Finland
Thyroiditis, Subacuta de Quervain
+∞
77.8
74
*
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
18.8
72.8
58
32
E06.0
ICD-10 Finland
Acute thyroiditis
+∞
71.4
68
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
666.0
65.4
64
*
BAA60
NOMESCO Finland
Total thyroidectomy
666.0
65.4
64
*
BA1AE, ,
SPAT
12.1
64.8
66
57
H02AB07
ATC
prednisone; oral
3.1
61.4
314
1189
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
25.0
55.1
39
16
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
12.1
54.3
55
47
R07.0
ICD-10 Finland
Pain in throat
3.5
51.5
196
617
C07AA05
ATC
propranolol; systemic
2.5
51.1
427
2061
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
20.0
50.3
39
20
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
+∞
50.3
48
*
24501
ICD-8 Finland
Thyroiditis, Subacuta alia
+∞
49.2
47
*
E06
ICD-10 Finland
Thyroiditis
482.4
47.6
47
*
R50.9
ICD-10 Finland
Fever, unspecified
2.5
39.7
293
1318
E06.3
ICD-10 Finland
Autoimmune thyroiditis
63.2
37.3
43
7
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
55.2
36.5
43
8
R53
ICD-10 Finland
Malaise and fatigue
2.1
34.2
461
2645
R21
ICPC
Throat symptom/complaint
2.1
34.0
416
2301
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
42.0
33.2
41
10
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
10.8
32.3
35
33
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
30.8
465
2761
A02BC02
ATC
pantoprazole; systemic
2.0
29.9
1098
8660
EP1AE, ,
SPAT
4.4
29.1
74
174
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
28.5
633
4242
R52.9
ICD-10 Finland
Pain, unspecified
2.4
27.1
200
890
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
52.7
26.3
31
6
E03.82
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
+∞
25.1
24
*
R51.80
ICD-10 Finland
Headache
2.0
24.5
306
1682
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
24.1
449
2818
A03
ICPC
Fever
2.0
23.6
310
1733
A02BC05
ATC
esomeprazole; systemic
1.7
23.3
661
4679
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
+∞
21.9
21
*
M79.6
ICD-10 Finland
Pain in limb
1.7
19.9
724
5403
T85
ICPC
Hyperthyroidism/thyrotoxicosis
36.3
19.9
25
7
G44.2
ICD-10 Finland
Tension-type headache
1.9
18.6
258
1460
M54.5
ICD-10 Finland
Low back pain
1.6
17.9
595
4307
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
17.6
831
6536
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
17.5
446
3012
A02BC03
ATC
lansoprazole; oral
1.7
17.2
438
2958
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
16.7
16
*
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
48.0
16.0
19
*
R06.0
ICD-10 Finland
Dyspnoea
1.7
16.0
394
2627
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
16.0
203
1112
J01AA02
ATC
doxycycline; systemic
1.7
15.7
1185
10289
J02AC01
ATC
fluconazole; systemic
1.6
15.3
694
5341
A02BC01
ATC
omeprazole; systemic
1.6
15.3
404
2738
N03AX16
ATC
[U] pregabalin
1.7
15.0
347
2273
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.0
15.0
174
923
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
14.5
422
2925
R42
ICD-10 Finland
Dizziness and giddiness
1.7
14.4
347
2294
K30
ICD-10 Finland
Functional dyspepsia
1.9
14.3
200
1130
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
14.0
347
2309
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
30.3
13.9
18
6
N01
ICPC
Headache
1.9
13.9
200
1140
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
+∞
13.6
13
*
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
+∞
13.6
13
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
13.6
13
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.9
13.4
63
223
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
13.4
472
3410
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.8
13.4
213
1251
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
13.4
300
1943
P01AB01
ATC
metronidazole; oral, rectal
1.5
13.3
646
4998
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
13.2
300
1948
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.2
13.1
107
495
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
13.1
644
4994
R03AC02
ATC
salbutamol; inhalant
1.5
12.8
845
6939
M79.7
ICD-10 Finland
Fibromyalgia
2.6
12.8
73
287
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
12.7
210
1248
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
2.4
12.6
85
362
J01DA01
ATC
[U] cefalexin
1.5
12.5
912
7627
C07AB07
ATC
bisoprolol; oral
1.5
12.3
621
4821
A04
ICPC
Weakness/tiredness general
1.7
12.3
238
1478
R51
ICD-10 Finland
Headache
2.2
12.2
102
476
R01AD09
ATC
mometasone; nasal
1.5
12.1
707
5643
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.4
12.1
43
129
R13
ICD-10 Finland
Dysphagia
2.2
12.0
106
506
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
12.0
391
2764
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
11.9
498
3713
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
2.6
11.9
71
285
R00.2
ICD-10 Finland
Palpitations
1.9
11.7
144
779
SPAT1283
SPAT
Restricted health certificate
1.6
11.5
271
1770
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
11.5
11
*
D01
ICPC
Abdominal pain/cramps general
1.8
11.4
204
1237
R01AD08
ATC
fluticasone; nasal
1.5
11.3
440
3227
J01FA10
ATC
azithromycin; systemic
1.5
11.2
882
7410
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.1
11.1
114
577
UJF32
NOMESCO Finland
Coloscopy
1.5
10.8
358
2531
L17
ICPC
Foot/toe symptom/complaint
1.5
10.8
462
3447
N06AX11
ATC
mirtazapine; oral
1.5
10.7
498
3776
M03BX02
ATC
tizanidine; oral
1.4
10.7
948
8114
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
10.5
230
1474
M25.5
ICD-10 Finland
Pain in joint
1.5
10.4
526
4049
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
110.8
10.4
11
*
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
10.4
349
2472
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
2.2
10.4
93
447
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
10.3
196
1208
R83
ICPC
Respiratory infection other
1.5
10.2
402
2943
SPAT1301
SPAT
No procedures
1.5
10.2
416
3067
Z01.2
ICD-10 Finland
Dental examination
1.4
10.2
706
5752
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
10.2
161
941
R01AD58
ATC
fluticasone, combinations; nasal
1.5
10.2
397
2901
R03DC03
ATC
montelukast; oral
1.6
10.2
263
1755
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
10.2
262
1747
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
10.1
293
2007
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
10.1
200
1246
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
10.0
251
1662
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
10.0
141
796
L04
ICPC
Chest symptom/complaint
2.0
9.9
112
587
D11
ICPC
Diarrhoea
1.7
9.8
190
1177
L02
ICPC
Back symptom/complaint
1.7
9.8
169
1015
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
9.7
285
1959
G43.9
ICD-10 Finland
Migraine, unspecified
2.0
9.7
111
586
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.4
9.6
63
265
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
9.6
119
645
J01MA02
ATC
ciprofloxacin; systemic
1.4
9.5
504
3900
N03AX12
ATC
[U] gabapentin; oral
1.6
9.5
235
1550
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
9.5
229
1501
R06AX27
ATC
desloratadine; oral
1.5
9.5
455
3457
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
9.5
84
403
H53.1
ICD-10 Finland
Subjective visual disturbances
2.0
9.5
109
576
M79.1
ICD-10 Finland
Myalgia
1.6
9.4
243
1618
J45
ICD-10 Finland
Asthma
1.7
9.4
168
1018
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
+∞
9.4
9
*
R74
ICPC
Upper respiratory infection acute
1.4
9.4
523
4085
D06
ICPC
Abdominal pain localized other
1.8
9.3
146
851
Z71.8
ICD-10 Finland
Other specified counselling
1.4
9.2
523
4094
M54.3
ICD-10 Finland
Sciatica
2.0
9.2
94
476
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
9.2
109
582
C07AB02
ATC
metoprolol; systemic
1.6
9.1
236
1572
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
9.1
142
827
N17
ICPC
Vertigo/dizziness
1.7
9.1
189
1194
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
9.1
283
1969
J01FA06
ATC
roxithromycin; oral
1.4
9.0
571
4551
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
9.0
622
5032
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
36.9
9.0
11
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.8
9.0
134
771
H02AB04
ATC
methylprednisolone; systemic
1.6
8.9
203
1311
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
8.9
195
1248
R12
ICD-10 Finland
Heartburn
1.8
8.9
136
788
J01FA09
ATC
clarithromycin; systemic
1.4
8.9
452
3465
N30.0
ICD-10 Finland
Acute cystitis
1.5
8.7
279
1949
L03
ICPC
Low back symptom/complaint
1.4
8.7
441
3376
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
8.6
110
602
R05
ICPC
Cough
1.5
8.6
379
2825
N02AX02
ATC
tramadol; systemic, rectal
1.4
8.6
575
4617
S04
ICPC
Lump/swelling localized
1.7
8.5
167
1037
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.8
8.5
119
671
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
8.5
265
1842
E06.5
ICD-10 Finland
Other chronic thyroiditis
90.6
8.4
9
*
UJD02
NOMESCO Finland
Gastroscopy
2.2
8.4
68
315
N89
ICPC
Migraine
2.2
8.3
68
316
A02BC04
ATC
rabeprazole; oral
1.7
8.3
141
842
R01AD12
ATC
fluticasone furoate; nasal
1.4
8.3
475
3712
J35.0
ICD-10 Finland
Chronic tonsillitis
2.0
8.2
82
413
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
8.1
122
703
L01
ICPC
Neck symptom/complaint
1.5
8.1
261
1825
WZC00, ,
SPAT
1.6
8.0
208
1385
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
7.9
330
2430
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.8
1073
9614
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
7.8
378
2862
M54
ICD-10 Finland
Dorsalgia
1.6
7.8
185
1208
E04.8
ICD-10 Finland
Other specified nontoxic goitre
45.2
7.7
9
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
7.7
204
1365
SPAT1263
SPAT
Sampling
1.4
7.7
564
4576
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
7.7
132
791
N02BE01
ATC
paracetamol; systemic, rectal
1.6
7.7
1328
12403
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
7.7
120
700
R02
ICPC
Shortness of breath/dyspnoea
1.6
7.6
182
1188
J01
ICD-10 Finland
Acute sinusitis
1.9
7.6
93
502
M01AH05
ATC
etoricoxib; oral
1.4
7.6
925
8112
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
7.6
154
966
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
7.6
362
2732
N05CF01
ATC
zopiclone; oral
1.4
7.5
425
3305
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
7.4
388
2975
SFA20
NOMESCO Finland
Two-surface restoration
1.3
7.4
867
7544
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.1
7.4
67
325
J01DB01
ATC
cefalexin; oral
1.4
7.3
1208
11093
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.4
7.3
48
203
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
7.3
81
423
R39.1
ICD-10 Finland
Other difficulties with micturition
2.8
7.3
36
132
D02
ICPC
Abdominal pain epigastric
1.8
7.3
99
553
T81
ICPC
Goitre
10.9
7.3
13
12
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
7.3
7
*
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
7.3
7
*
G50.1
ICD-10 Finland
Atypical facial pain
2.8
7.2
34
122
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
7.1
95
528
R52
ICD-10 Finland
Pain, not elsewhere classified
3.8
7.1
21
56
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
7.1
774
6649
R07.3
ICD-10 Finland
Other chest pain
1.6
7.1
147
928
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.8
7.0
107
620
R05
ICD-10 Finland
Cough
1.4
7.0
306
2269
R49.01
ICD-10 Finland
Functional dysphonia
2.3
7.0
52
233
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.0
186
1247
K11.2
ICD-10 Finland
Sialoadenitis
2.4
7.0
48
208
M01AB05
ATC
diclofenac; systemic, rectal
1.3
7.0
945
8369
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.2
6.9
54
247
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.9
575
4740
Z01.7
ICD-10 Finland
Laboratory examination
1.5
6.9
243
1730
M54.6
ICD-10 Finland
Pain in thoracic spine
1.7
6.8
120
724
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
6.8
436
3448
H92.0
ICD-10 Finland
Otalgia
1.8
6.8
102
588
A11
ICPC
Chest pain NOS
1.7
6.8
114
679
XQ800
NOMESCO Finland
Prick test
1.7
6.8
116
695
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
2.0
6.7
73
379
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.7
736
6304
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.9
6.7
19
49
H57.1
ICD-10 Finland
Ocular pain
2.1
6.7
64
317
R06AX13
ATC
loratadine; oral
1.5
6.7
227
1603
M01AE02
ATC
naproxen; oral, rectal
1.3
6.6
821
7149
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.0
6.6
66
332
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.6
848
7419
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
6.6
423
3342
R03AC03
ATC
terbutaline; inhalant
1.5
6.6
195
1338
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
6.6
608
5080
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.3
6.5
45
195
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
6.5
140
891
A29
ICPC
General symptom/complaint other
1.5
6.5
176
1185
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.4
476
3844
A05
ICPC
Feeling ill
1.8
6.3
85
474
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
6.3
293
2193
P06
ICPC
Sleep disturbance
1.5
6.3
182
1242
D73
ICPC
Gastroenteritis presumed infection
2.2
6.3
53
251
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
+∞
6.3
6
*
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
6.3
6
*
N06AX21
ATC
duloxetine; oral
1.5
6.1
169
1140
M35.7
ICD-10 Finland
Hypermobility syndrome
2.9
6.1
28
99
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.1
590
4945
N64.4
ICD-10 Finland
Mastodynia
2.0
6.1
62
315
T74.1
ICD-10 Finland
Physical abuse
2.8
6.1
29
105
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.1
787
6864
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.1
665
5670
R06AE09
ATC
levocetirizine; oral
1.5
6.0
204
1437
H01
ICPC
Ear pain/earache
1.5
6.0
173
1179
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
299
152
24.26
307.65
1.9
1.2
2.68
1.60
iu/l
4.21
109
37
498
741
9.52
307.65
1.5
1.2
165.96
71.74
u/ml
3.72
229
237
344
461
9.36
252.24
3.4
1.4
4.77
4.45
pmol/l
2.79
314
401
1385
10512
4.70
72.20
8.7
2.8
15.17
14.34
pmol/l
22.83
1331
9689
1282
9990
2.84
48.76
6.3
4.3
12.41
11.72
mm/h
1.07
1233
9395
48
41
12.06
47.36
2.6
1.1
186.43
53.46
u/ml
—
20
5
1434
12441
3.85
34.71
10.2
3.9
1.81
1.86
mu/l
0.56
1380
11604
473
2832
1.97
30.52
1.9
1.6
—
—
—
0
0
994
7767
1.81
25.68
9.0
9.6
3.99
4.02
e9/l
0.18
898
6754
92
284
3.38
24.61
1.4
1.2
—
—
—
0
0
241
1222
2.16
23.86
2.0
1.9
373.96
379.60
nmol/l
0.19
227
1129
846
6412
1.72
23.22
6.4
6.6
1.22
1.22
mmol/l
1.09
745
5587
554
3912
1.66
18.54
2.3
2.1
121.02
206.21
u/l
2.66
527
3733
748
5717
1.61
18.00
5.8
6.0
1.22
1.22
mmol/l
0.32
699
5318
1440
13231
2.78
17.79
18.5
14.3
19.43
22.43
mg/l
3.67
1288
10764
426
2848
1.69
17.37
1.4
1.3
30.22
33.60
iu/ml
0.20
127
859
1187
10235
1.74
17.08
8.4
8.0
76.30
77.52
u/l
0.30
1136
9734
574
4198
1.59
16.08
2.7
2.5
58.04
62.24
u/l
0.67
544
3913
627
4694
1.57
15.81
3.8
3.4
25.23
41.34
ng/l
1.02
375
3031
449
3107
1.63
15.75
1.7
1.7
0.75
1.05
mg/l
3.00
345
2399
168
883
2.02
14.82
1.4
1.3
29.35
39.49
au/ml
0.48
12
59
843
6805
1.54
14.77
3.7
3.0
102.77
101.85
ug/l
0.03
790
6434
421
2916
1.61
14.51
1.5
1.5
2.13
2.33
g/l
2.03
259
1817
476
3395
1.59
14.51
1.4
1.3
0.87
1.46
u/ml
1.28
124
894
178
965
1.96
14.37
2.6
2.4
18.81
20.70
au/ml
0.15
29
103
917
7597
1.52
13.80
4.6
4.6
6.35
6.52
mmol/l
2.28
881
7143
383
2630
1.61
13.54
1.4
1.3
8.40
11.27
u/ml
0.52
171
1009
872
7211
1.49
12.77
4.5
3.9
0.01
0.00
estimate
0.34
172
1434
292
1904
1.66
12.60
2.3
2.5
87.40
107.42
ug/g
1.02
223
1506
884
7356
1.48
12.36
4.6
3.9
0.00
0.22
estimate
0.53
168
1414
877
7288
1.48
12.33
4.6
3.9
0.03
4.32
estimate
1.32
176
1487
725
5804
1.48
12.31
4.5
4.7
36.78
36.04
g/l
3.59
665
5474
742
6016
1.46
11.52
11.6
10.4
0.00
0.00
e9/l
0.34
619
4895
161
907
1.87
11.52
3.5
3.7
72.96
84.01
ng/l
1.18
138
788
1030
8910
1.49
11.32
5.4
4.6
1718.33
2560.19
e6/l
0.19
15
110
843
7027
1.45
11.15
6.0
6.4
9.98
10.80
umol/l
1.92
804
6721
772
6332
1.45
11.13
2.7
2.5
79.74
77.98
nmol/l
1.02
717
5816
1424
13378
2.07
10.56
18.2
16.0
139.75
139.69
mmol/l
0.45
1406
13122
1425
13408
2.06
10.24
18.4
16.1
3.94
3.94
mmol/l
0.44
1404
13113
593
4688
1.44
10.12
3.3
3.5
2.36
2.36
mmol/l
0.46
538
4279
117
637
1.91
9.30
1.7
2.1
6.37
8.72
iu/ml
0.39
32
156
529
4165
1.42
8.97
3.4
3.1
82.11
78.66
e6/l
0.02
413
3080
350
2555
1.48
8.88
1.7
1.7
17466210.57
39350781.63
pmol/l
0.52
292
2155
163
995
1.72
8.88
1.4
1.3
122.77
179.89
u/ml
0.93
154
921
463
3576
1.42
8.69
3.1
3.0
0.32
0.45
e6/l
0.86
352
2527
167
1037
1.69
8.54
2.7
2.7
10.11
10.65
g/l
1.12
150
959
422
3215
1.43
8.51
4.8
4.0
1.02
1.49
kg/l
0.50
283
2120
333
2428
1.48
8.46
4.2
3.5
101.71
365.27
ng/l
2.51
215
1716
679
5622
1.38
8.37
11.2
12.4
1.14
1.19
inr
2.61
570
4584
104
565
1.90
8.33
1.8
2.1
38.34
40.05
u/l
0.38
94
513
498
3929
1.40
8.17
4.8
4.0
0.00
0.01
estimate
1.54
168
1382
1326
12348
1.59
8.14
6.2
5.7
38.31
38.46
mmol/mol
0.30
1257
11639
666
5514
1.37
8.14
4.2
3.7
0.01
0.13
estimate
0.80
135
1187
1458
13957
2.19
8.03
13.6
11.5
24.67
24.76
u/l
0.08
1431
13614
1358
12732
1.64
7.95
5.2
4.7
5.71
5.80
mmol/l
2.68
1285
11777
685
5712
1.36
7.93
2.1
2.0
101.55
97.57
pmol/l
1.22
332
2930
434
3362
1.41
7.87
2.3
2.3
2.48
2.81
mg/l
2.99
377
2928
86
454
1.95
7.52
1.5
1.3
—
—
—
0
0
438
3423
1.39
7.48
2.9
2.9
786.16
1114.27
ng/l
1.41
380
2892
1460
14015
2.15
7.45
21.0
18.1
72.06
71.13
umol/l
0.72
1454
13867
1404
13312
1.75
7.44
6.0
5.4
2.84
2.80
mmol/l
1.08
1323
12492
1000
8895
1.37
7.38
3.7
3.2
—
—
—
0
0
351
2649
1.42
7.31
2.8
2.8
2.43
2.45
mmol/l
2.84
314
2390
1389
13141
1.69
7.30
5.3
4.8
4.80
4.78
mmol/l
0.29
1314
12369
1384
13082
1.67
7.29
5.1
4.7
1.53
1.54
mmol/l
0.35
1307
12252
369
2817
1.41
7.19
2.7
2.5
6.16
6.72
e6/l
0.28
333
2538
102
582
1.81
7.03
1.3
1.3
0.28
1.68
u/ml
1.25
16
37
1219
11242
1.43
6.97
20.9
17.5
13.51
13.55
%
0.49
1211
11092
76
396
1.97
6.92
1.3
1.1
2.11
5.14
—
7
53
1353
12763
1.56
6.66
15.7
13.6
82.88
83.48
ml/min/173m2
0.54
1261
11716
413
3271
1.36
6.33
2.3
2.5
317.75
321.50
umol/l
0.32
370
2925
90
517
1.79
6.10
1.7
1.4
282.57
279.30
mu/l
0.04
78
468
449
3626
1.34
6.00
1.7
1.6
21.25
20.95
nmol/l
0.17
384
3079
148
981
1.56
5.82
2.5
2.8
67.18
67.13
g/l
0.03
136
911
67
356
1.92
5.81
1.7
2.1
9.99
12.41
mg/l
1.32
60
332
148
984
1.56
5.75
3.2
3.3
1.23
1.23
mmol/l
0.24
121
861
32
126
2.57
5.72
1.3
1.3
39.38
22.49
ng/l
0.51
32
126
81
462
1.80
5.64
1.4
1.5
0.02
0.18
iu/ml
0.71
17
81
13
20
6.55
5.56
1.2
1.1
95.77
98.05
%
0.07
13
20
192
1361
1.47
5.51
3.8
4.6
227.41
249.29
u/l
1.26
186
1292
187
1322
1.47
5.44
2.3
2.3
53.74
39.67
u/l
0.35
159
1105
138
920
1.55
5.30
1.3
1.4
25.78
28.74
iu/l
0.48
116
797
212
1559
1.42
5.00
2.5
2.8
4.76
7.44
umol/l
3.97
178
1370
1311
12419
1.41
4.98
4.4
4.0
1.23
1.25
mmol/l
0.44
1235
11517
83
496
1.71
4.95
1.7
1.7
—
—
—
0
0
1482
14446
2.19
4.95
27.4
21.7
261.58
259.16
e9/l
0.81
1470
14172
548
4646
1.28
4.93
3.1
3.2
28.32
31.08
u/l
1.75
529
4405
1482
14447
2.19
4.93
27.2
21.7
90.60
91.00
fl
3.25
1474
14310
19
61
3.14
4.92
1.6
3.2
656.95
810.36
u/ml
0.27
19
61
1482
14449
2.18
4.89
27.6
22.1
40.21
39.96
%
1.49
1474
14305
1482
14450
2.18
4.87
27.3
21.7
4.47
4.45
e12/l
1.11
1465
14130
1482
14450
2.18
4.87
27.3
21.8
6.68
6.66
e9/l
0.14
1467
14123
75
439
1.75
4.82
1.4
1.3
—
—
—
0
0
1482
14456
2.16
4.77
27.5
21.9
133.92
133.58
g/l
0.49
1475
14319
272
2102
1.36
4.75
2.7
3.3
0.83
0.82
mmol/l
0.55
254
1999
62
347
1.82
4.64
1.2
1.3
0.92
4.97
u/ml
—
5
27
286
2237
1.34
4.61
2.8
2.8
1.01
1.25
e6/l
0.36
163
1128
257
1979
1.36
4.59
2.5
2.3
2.41
2.35
g/l
0.99
240
1843
73
432
1.72
4.54
2.6
2.3
9.97
10.40
g/l
0.40
63
390
505
4280
1.27
4.46
3.2
3.2
7.24
7.25
mmol/l
0.02
432
3643
65
375
1.77
4.42
2.9
2.2
0.00
0.00
g/l
0.50
56
339
44
225
1.98
4.33
1.1
1.1
2.13
4.10
—
6
37
82
508
1.65
4.31
2.6
2.3
7.56
7.43
g/l
0.23
73
468
470
3962
1.27
4.31
3.3
3.3
0.45
0.25
estimate
0.19
133
1158
78
479
1.66
4.25
2.7
2.3
2.87
2.95
g/l
0.33
69
439
72
435
1.69
4.17
2.8
2.4
0.51
1.01
g/l
0.77
59
381
273
2151
1.33
4.17
2.5
2.3
13.89
13.33
umol/l
0.57
254
2012
40
201
2.02
4.14
1.4
1.3
—
—
—
0
0
143
1013
1.45
4.14
1.5
1.5
—
—
—
0
0
81
508
1.63
4.08
2.6
2.3
4.18
4.27
g/l
0.54
72
467
81
508
1.63
4.08
2.6
2.3
3.64
3.76
g/l
0.39
71
468
207
1570
1.37
4.06
2.2
2.1
—
—
—
0
0
15
47
3.21
4.06
1.0
1.0
—
—
—
0
0
22
86
2.58
4.06
2.0
2.3
—
—
—
0
0
144
1026
1.45
4.05
2.7
2.2
0.16
0.57
e6/l
2.74
126
968
31
144
2.18
3.94
1.5
1.6
567.04
315.80
mu/l
0.37
24
119
61
359
1.73
3.90
2.9
2.3
0.00
0.00
g/l
-0.00
51
315
128
899
1.46
3.88
1.7
1.7
—
—
—
0
0
224
1733
1.34
3.87
2.3
2.2
—
—
—
0
0
84
541
1.59
3.81
2.6
2.1
10.83
11.39
nmol/l
0.22
77
487
233
1818
1.33
3.80
2.5
2.4
23.07
22.83
%
0.08
215
1708
30
141
2.15
3.72
1.2
1.1
—
—
—
0
0
55
319
1.75
3.72
1.9
1.3
11.05
11.97
u/l
0.19
48
255
50
282
1.80
3.71
1.0
1.1
3.29
3.77
u/ml
0.14
23
152
49
275
1.81
3.70
1.2
1.1
38.99
19.08
au/ml
—
7
71
56
330
1.72
3.59
3.0
2.3
0.00
0.00
g/l
-0.00
51
314
31
153
2.05
3.42
1.2
1.2
—
—
—
0
0
43
238
1.83
3.41
2.2
1.6
—
—
—
0
0
88
589
1.52
3.40
1.6
1.6
10.21
11.77
u/ml
0.18
17
132
239
1904
1.30
3.36
1.6
1.7
1287.62
1203.41
nmol/l
0.69
180
1440
25
115
2.19
3.29
1.1
1.1
—
—
—
0
0
647
5776
1.21
3.28
2.0
1.9
1.31
1.35
mmol/l
0.69
533
4966
252
2032
1.29
3.23
3.1
2.9
3.07
3.53
e6/l
0.40
133
930
26
124
2.12
3.15
1.1
1.1
—
—
—
0
0
200
1569
1.32
3.15
4.8
5.4
1.02
1.04
mmol/l
0.38
188
1456
25
118
2.14
3.11
1.1
1.1
—
—
—
0
0
25
118
2.14
3.11
1.1
1.1
—
—
—
0
0
38
209
1.84
3.10
1.2
1.1
—
2.88
—
0
8
67
435
1.57
3.00
1.3
1.3
2.23
7.79
u/ml
—
7
72
234
1889
1.28
2.97
1.7
2.0
29.35
29.22
s
0.10
228
1828
46
273
1.71
2.93
1.0
1.1
0.58
1.29
u/ml
0.72
20
119
24
115
2.10
2.89
1.1
1.1
—
—
—
0
0
15
58
2.60
2.87
1.3
2.4
23.67
155.33
ug/l
0.47
15
51
60
385
1.58
2.84
3.0
3.6
30.02
56.63
mg/l
1.33
53
339
60
385
1.58
2.84
3.0
3.6
802.09
71.10
mg/l
0.46
53
340
46
276
1.69
2.83
1.0
1.1
2.27
1.06
u/ml
0.24
19
136
93
661
1.43
2.72
2.8
2.1
4631.14
6203.95
u/l
0.21
42
276
151
1166
1.33
2.67
2.4
2.0
—
—
—
0
0
122
912
1.37
2.67
2.1
2.2
4.46
6.64
ug/l
1.57
109
811
39
229
1.72
2.61
1.0
1.1
2.94
5.69
u/ml
0.53
14
98
25
127
1.98
2.61
1.1
1.2
0.01
0.32
u/ml
1.83
14
58
36
207
1.76
2.59
1.3
1.2
0.51
9.29
nmol/l
0.51
36
196
17
74
2.31
2.58
1.5
1.5
33.21
35.96
nmol/l
0.17
17
62
96
698
1.40
2.50
6.2
7.4
24.64
24.47
mmol/l
0.22
91
664
53
342
1.57
2.48
2.8
3.3
46.94
3.21
ratio
0.46
24
190
18
82
2.21
2.48
1.7
1.2
9.33
9.09
mm/h
0.05
18
82
699
6396
1.17
2.45
2.7
2.7
—
—
estimate
—
0
0
52
336
1.57
2.43
1.1
1.1
0.23
2.07
u/ml
3.82
24
177
11
38
2.91
2.41
1.2
1.2
—
—
—
0
0
23
117
1.98
2.41
1.2
1.1
8.60
13.47
u/ml
—
7
52
72
502
1.46
2.37
1.6
2.0
1.44
1.51
g/l
0.24
62
439
107
803
1.36
2.32
1.1
1.0
—
—
—
0
0
390
3412
1.19
2.31
3.4
3.9
97.22
93.80
%
2.52
383
3339
245
2049
1.23
2.31
1.9
1.9
—
—
—
0
0
9
28
3.23
2.31
6.7
3.4
10.19
10.30
kpa
—
9
28
9
28
3.23
2.31
6.7
3.4
5.70
4.72
kpa
—
9
28
57
382
1.51
2.28
1.1
1.1
0.66
5.13
eliau/ml
—
7
51
40
248
1.63
2.23
1.1
1.0
4.37
2.49
u/ml
0.21
15
120
12
48
2.51
2.18
1.3
2.2
6.30
10.72
mg/l
2.70
12
41
109
829
1.34
2.18
2.2
2.7
100.21
169.20
ng/l
1.69
101
747
33
196
1.70
2.16
1.5
1.4
—
—
—
0
0
38
236
1.63
2.12
5.7
8.1
104.09
105.06
mmol/l
0.47
33
211
51
340
1.52
2.11
1.4
1.5
—
—
—
0
0
41
260
1.59
2.10
1.5
1.4
—
—
—
0
0
47
311
1.53
2.02
1.5
1.3
—
—
—
0
0
352
3088
1.18
2.01
1.6
1.5
—
—
—
0
0
38
240
1.60
2.00
2.6
2.5
44.92
84.43
ug/min
0.58
28
142
15
70
2.15
1.98
1.3
1.1
—
—
—
0
0
16
77
2.09
1.97
1.1
1.1
—
—
—
0
0
58
404
1.45
1.96
1.4
1.3
—
—
—
0
0
5
11
4.56
1.94
1.0
1.0
0.07
0.27
u/ml
—
5
11
450
4041
1.16
1.91
4.0
3.9
5.98
8.14
mg/mmol
0.54
259
2408
72
528
1.38
1.85
3.9
5.4
1.60
1.53
%
0.33
66
496
21
115
1.84
1.83
1.1
1.1
122.81
113.77
pmol/l
0.43
21
115
9
35
2.58
1.80
1.1
1.1
—
—
—
0
0
37
240
1.56
1.77
1.4
1.2
2.13
2.94
u/ml
0.35
16
80
35
226
1.56
1.71
1.7
1.3
22.11
27.60
u/l
0.48
27
193
33
211
1.58
1.69
1.1
1.0
0.03
0.16
u/ml
0.98
11
69
15
76
1.98
1.64
1.1
1.0
2409.34
1550.00
miu/ml
1.74
15
76
33
213
1.56
1.63
1.2
1.2
—
0.41
nmol/l
—
0
8
5
14
3.58
1.61
1.4
1.4
1.17
1.24
mmol/l
—
5
14
12
56
2.15
1.61
1.6
2.1
—
—
—
0
0
10
43
2.33
1.59
5.9
4.1
—
—
—
0
0
969
9244
1.13
1.57
3.5
3.2
37.59
43.39
u/l
2.24
926
8758
34
224
1.53
1.55
2.0
2.2
3.82
5.42
umol/l
1.16
28
159
118
955
1.26
1.55
2.2
1.9
—
—
—
0
0
72
546
1.33
1.54
1.3
1.6
0.21
0.36
mg/l
2.36
19
242
18
100
1.81
1.53
1.1
1.3
—
—
—
0
0
81
626
1.31
1.52
1.4
1.5
—
—
—
0
0
6
21
2.86
1.50
1.0
1.2
—
—
—
0
0
128
1051
1.24
1.48
2.2
2.3
70.39
71.02
ml/min/173m2
0.07
48
443
50
361
1.40
1.46
1.6
1.5
—
—
—
0
0
179
1527
1.20
1.43
1.9
1.8
—
—
—
0
0
39
271
1.45
1.40
1.3
1.5
0.37
0.45
nmol/l
0.36
34
212
7
29
2.42
1.39
1.0
1.6
119.86
105.38
%
—
7
29
172
1467
1.19
1.38
1.9
1.8
—
—
—
0
0
15
82
1.84
1.36
1.8
1.4
10.37
11.54
umol/l
0.31
15
76
49
358
1.38
1.35
1.5
1.4
—
—
—
0
0
168
1433
1.19
1.35
5.6
4.6
20.49
21.14
%
0.26
90
676
13
68
1.92
1.33
1.2
1.1
—
—
—
0
0
9
43
2.10
1.30
1.3
1.3
—
—
—
0
0
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
17
99
1.73
1.27
1.3
1.5
—
—
—
0
0
9
44
2.05
1.27
1.4
1.3
—
—
—
0
0
21
131
1.61
1.23
1.3
1.6
—
—
—
0
0
9
45
2.01
1.23
2.1
1.5
7.60
8.57
ug/l
—
9
45
36
254
1.43
1.22
1.4
1.4
140.78
160.69
au/ml
—
9
67
19
116
1.65
1.21
1.2
1.1
7.62
7.87
iu/ml
—
5
36
27
181
1.50
1.18
1.2
1.2
0.19
0.18
nmol/l
0.10
21
139
5
20
2.50
1.15
1.2
1.1
—
—
—
0
0
50
379
1.33
1.13
1.5
1.4
322.19
303.77
ug/g
0.22
27
220
19
119
1.60
1.12
1.6
1.8
—
—
—
0
0
31
219
1.42
1.07
1.1
1.1
—
—
—
0
0
27
186
1.46
1.06
1.6
1.3
6.23
7.21
mmol/l
1.29
21
160
17
105
1.63
1.06
1.9
1.5
45.08
29.85
%
0.73
12
65
186
1640
1.15
1.03
6.2
7.0
104.70
104.22
mmol/l
0.81
186
1640
18
114
1.59
1.02
1.8
1.7
7.00
7.88
mmol/l
1.07
18
109
18
114
1.59
1.02
1.3
1.7
—
—
—
0
0
54
422
1.29
1.01
1.4
2.3
400.30
442.80
ug/l
0.06
48
395
9
48
1.88
1.00
1.1
1.1
241.00
193.66
iu/ml
—
9
48
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
45
345
1.31
0.97
1.6
1.7
8821.88
10764.09
e6/l
0.24
34
245
7
36
1.95
0.97
1.4
1.1
—
—
—
0
0
33
241
1.38
0.97
1.8
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
69
1.75
0.96
1.3
1.1
—
—
—
0
0
134
1160
1.17
0.96
7.1
8.7
123.22
119.79
g/l
1.19
129
1133
7
37
1.90
0.94
1.4
1.1
—
—
—
0
0
7
37
1.90
0.94
1.4
1.1
—
—
—
0
0
32
234
1.38
0.94
1.3
1.2
3.58
2.66
u/ml
0.39
12
93
10
55
1.82
0.92
1.4
1.3
—
—
—
0
0
34
257
1.33
0.83
3.0
3.5
21.23
25.56
mg/l
0.36
24
179
81
681
1.20
0.83
3.0
3.3
1.02
1.02
ratio
0.27
73
615
40
310
1.30
0.83
1.6
1.5
3851.69
1286.43
e6/l
0.29
35
237
6
32
1.88
0.82
1.0
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
42
330
1.28
0.79
2.3
3.2
0.49
0.38
iu/ml
0.44
24
172
62
746
0.82
0.77
10.0
9.3
24.58
24.33
mmol/l
0.28
62
738
86
734
1.18
0.76
1.6
1.7
—
—
—
0
0
137
1213
1.14
0.76
7.1
8.4
96.09
95.82
%
0.20
130
1176
18
124
1.46
0.75
1.1
1.2
—
—
—
0
0
11
67
1.65
0.75
1.5
1.6
—
632799.86
—
0
7
11
67
1.65
0.75
2.1
1.2
3.84
5.52
umol/l
1.42
11
59
159
1424
1.13
0.74
6.4
6.1
—
—
—
0
0
22
158
1.40
0.74
1.6
1.4
—
—
—
0
0
13
84
1.55
0.72
1.7
2.8
0.69
0.73
e9/l
0.16
13
79
12
76
1.58
0.71
1.3
1.3
—
1308.33
—
0
6
38
300
1.27
0.71
1.5
1.4
85.10
33.46
e6/l
0.27
31
211
7
41
1.71
0.70
2.4
1.2
186.73
143.23
pmol/l
—
7
41
5
27
1.85
0.68
1.0
1.2
—
—
—
0
0
22
161
1.37
0.68
1.6
1.5
—
—
—
0
0
46
375
1.23
0.67
2.2
2.5
—
—
—
0
0
54
449
1.21
0.66
2.1
1.9
2.05
1.98
ug/l
0.03
43
397
63
532
1.19
0.65
1.5
1.3
273.84
239.96
miu/ml
0.29
29
265
97
1103
0.87
0.64
7.3
7.4
1.23
1.29
mmol/l
0.32
97
1086
14
95
1.48
0.64
1.3
1.3
—
—
—
0
0
5
30
1.67
0.61
1.2
1.2
—
—
—
0
0
44
362
1.22
0.60
1.2
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.9
—
7.38
—
0
11
8
54
1.48
0.57
1.0
1.1
—
—
—
0
0
33
265
1.25
0.57
1.5
1.7
—
—
—
0
0
6
37
1.62
0.55
1.5
1.5
44.00
28.73
%
—
6
26
120
1081
1.12
0.55
3.5
3.2
0.66
0.74
ug/l
0.99
81
693
18
133
1.36
0.55
1.1
1.3
116973.92
122165.76
e6/l
0.02
12
90
21
160
1.32
0.53
1.7
1.5
—
—
—
0
0
34
277
1.23
0.53
1.3
1.2
364.87
260.40
u/ml
0.36
23
168
9
63
1.43
0.52
1.0
1.0
—
—
—
0
0
20
152
1.32
0.52
1.7
1.5
—
—
—
0
0
6
40
1.50
0.51
1.2
1.4
—
—
—
0
0
20
153
1.31
0.50
1.7
1.5
—
—
—
0
0
20
153
1.31
0.50
1.7
1.5
—
—
—
0
0
16
118
1.36
0.50
1.1
1.1
—
—
—
0
0
7
45
1.56
0.49
1.4
1.2
—
—
—
0
0
83
739
1.13
0.48
1.7
1.5
—
—
—
0
0
53
457
1.17
0.47
1.8
1.9
—
—
—
0
0
20
155
1.29
0.47
1.9
2.3
13.43
23.15
mg/l
—
7
62
133
1219
1.10
0.46
1.7
1.7
3.35
3.51
mmol/l
0.78
93
834
5
81
0.62
0.46
1.8
1.6
1.37
1.37
nmol/l
—
5
59
5
84
0.59
0.45
2.0
1.6
—
—
—
0
0
14
103
1.36
0.45
1.4
1.2
—
—
—
0
0
191
1783
1.08
0.45
6.4
5.4
3.53
2.26
ug/l
0.40
177
1601
43
369
1.17
0.42
1.7
3.9
25.19
24.91
mmol/l
0.34
38
342
10
70
1.43
0.41
1.1
1.1
—
—
—
0
0
13
96
1.36
0.41
1.4
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
8
59
1.36
0.41
1.4
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
7.8
—
10.08
—
0
18
148
1378
1.08
0.38
7.1
7.9
1.06
1.03
mmol/l
0.03
125
1136
21
169
1.25
0.38
2.5
2.6
35.80
47.48
iu/ml
—
5
19
16
124
1.29
0.38
1.4
1.6
—
—
—
0
0
9
66
1.37
0.38
1.0
1.6
—
—
—
0
0
9
66
1.37
0.38
1.0
1.6
—
—
—
0
0
9
66
1.37
0.38
1.0
1.6
—
—
—
0
0
9
66
1.37
0.38
1.0
1.6
—
—
—
0
0
40
345
1.16
0.38
1.9
3.4
2.52
2.12
index
0.20
23
184
12
89
1.35
0.38
1.3
1.3
75.17
75.13
umol/l
0.00
12
89
125
1157
1.09
0.38
3.9
3.6
1.85
1.84
mmol/l
0.01
113
1010
47
411
1.15
0.37
1.9
1.8
—
—
—
0
0
5
37
1.35
0.37
1.6
1.1
—
—
—
0
0
59
658
0.89
0.35
1.6
1.5
—
—
—
0
0
48
542
0.88
0.34
1.6
1.4
—
—
—
0
0
25
209
1.20
0.34
1.2
1.1
139.67
2980.03
iu/ml
—
9
43
6
45
1.33
0.33
1.8
1.6
0.60
0.46
e9/l
—
6
45
13
101
1.29
0.31
1.4
1.2
—
—
—
0
0
45
399
1.13
0.31
1.2
1.2
—
—
—
0
0
65
592
1.10
0.29
3.9
3.5
44.23
46.72
%
0.36
65
580
7
56
1.25
0.29
1.4
1.4
—
—
—
0
0
7
57
1.23
0.29
1.4
1.4
—
—
—
0
0
10
129
0.77
0.28
1.8
1.5
8.53
8.50
mmol/l
—
10
123
12
94
1.28
0.28
1.2
1.4
—
—
—
0
0
39
347
1.13
0.27
1.8
1.7
—
—
—
0
0
147
1393
1.06
0.26
7.1
8.0
13.05
12.76
kpa
0.21
141
1344
147
1393
1.06
0.26
7.1
8.0
5.00
5.11
kpa
0.83
141
1343
344
3334
1.04
0.26
2.4
2.2
—
—
—
0
0
20
169
1.19
0.26
2.9
4.1
16.94
65.77
u/ml
2.19
20
169
27
235
1.15
0.25
1.2
1.3
—
—
—
0
0
27
235
1.15
0.25
1.2
1.3
—
—
—
0
0
14
114
1.23
0.25
1.4
1.5
—
—
—
0
0
14
114
1.23
0.25
1.4
1.5
—
—
—
0
0
14
114
1.23
0.25
1.4
1.5
—
—
—
0
0
17
142
1.20
0.24
1.1
1.1
—
49.20
—
0
10
19
161
1.18
0.24
1.2
1.4
—
—
—
0
0
29
256
1.14
0.23
1.4
1.4
—
—
—
0
0
170
1627
1.05
0.23
2.0
1.9
3.35
3.35
ratio
0.00
127
1234
5
39
1.28
0.23
1.2
1.2
—
—
—
0
0
62
573
1.09
0.23
1.8
1.7
5.55
4.30
mg/l
0.24
49
431
18
153
1.18
0.22
1.6
2.1
30.50
31.90
pg
0.47
18
153
149
1560
0.95
0.22
1.8
1.7
1.33
1.40
%
1.23
139
1373
11
135
0.81
0.22
6.0
3.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
27
302
0.89
0.19
2.5
2.1
132.57
129.31
g/l
0.47
21
235
14
165
0.85
0.19
1.2
1.5
—
—
—
0
0
15
128
1.17
0.18
1.1
1.1
—
—
—
0
0
7
60
1.17
0.17
1.6
1.7
—
—
—
0
0
7
60
1.17
0.17
1.6
1.6
—
—
—
0
0
36
329
1.10
0.17
1.9
1.6
—
—
—
0
0
7
61
1.15
0.17
1.7
1.7
—
—
—
0
0
43
397
1.09
0.17
1.2
1.2
—
—
—
0
0
42
454
0.92
0.17
1.6
1.5
0.92
1.18
ratio
1.58
25
282
42
454
0.92
0.17
1.6
1.5
1.15
1.16
ratio
0.03
25
281
42
454
0.92
0.17
1.6
1.5
1.08
0.95
ratio
0.98
25
281
130
1249
1.04
0.16
2.8
3.1
—
—
—
0
0
10
120
0.83
0.16
2.1
2.7
—
—
—
0
0
8
70
1.14
0.16
1.3
1.2
67.88
76.12
u/l
—
8
59
6
78
0.77
0.15
1.5
1.4
—
—
—
0
0
42
451
0.93
0.15
1.6
1.4
—
—
—
0
0
7
90
0.78
0.14
1.3
1.0
—
—
—
0
0
24
218
1.10
0.13
1.5
1.2
—
—
—
0
0
23
209
1.10
0.13
1.1
1.0
1.39
2.28
eliau/ml
0.77
11
95
14
123
1.14
0.12
1.1
1.1
—
37.50
—
0
6
65
681
0.95
0.12
4.2
3.9
24.88
24.25
mmol/l
1.14
65
675
72
689
1.05
0.12
9.6
10.1
16.17
15.81
%
0.61
67
660
62
591
1.05
0.12
2.4
3.4
1.64
1.84
mmol/l
0.22
50
450
80
769
1.04
0.11
8.2
9.8
0.69
0.65
%
0.41
80
764
5
44
1.14
0.10
1.6
1.4
—
—
—
0
0
5
44
1.14
0.10
1.6
1.4
—
—
—
0
0
5
48
1.04
0.09
1.0
1.8
—
—
—
0
0
11
97
1.14
0.09
1.2
1.4
—
—
—
0
0
155
1583
0.98
0.08
5.0
4.7
32.70
32.63
%
0.03
119
1050
73
754
0.97
0.08
1.5
1.4
—
—
—
0
0
8
76
1.05
0.07
1.6
3.6
0.75
0.78
index
—
8
76
16
147
1.09
0.07
3.5
3.2
2.60
43.23
nmol/l
0.55
16
142
7
81
0.86
0.07
1.1
1.6
—
—
—
0
0
47
487
0.96
0.06
1.6
1.5
69.61
61.80
ug/l
0.41
39
404
13
141
0.92
0.05
1.1
1.1
—
—
—
0
0
41
396
1.04
0.05
1.6
1.6
—
—
—
0
0
81
794
1.02
0.04
8.4
9.6
1.35
1.30
%
0.14
81
787
20
211
0.95
0.04
3.2
3.6
0.95
0.81
nmol/l
0.43
15
185
81
795
1.02
0.04
8.4
9.7
93.98
94.07
%
0.04
81
789
52
507
1.03
0.04
1.1
1.1
0.62
0.62
ratio
—
6
73
19
181
1.05
0.03
1.1
1.2
—
—
—
0
0
82
831
0.99
0.02
1.6
1.6
831.89
1030.22
mu/l
1.40
68
675
55
541
1.02
0.02
1.2
1.1
1.54
1.59
g/l
0.75
55
541
28
288
0.97
0.02
1.7
1.5
48.09
59.18
ug/l
0.89
28
288
137
1379
0.99
0.01
3.5
4.3
7.17
23.65
ug/l
1.51
111
1101
72
712
1.01
0.01
2.9
3.3
5.30
5.17
kpa
0.73
65
684
10
94
1.06
0.01
1.3
1.5
—
—
—
0
0
23
224
1.03
0.00
1.3
1.6
—
—
—
0
0
55
556
0.99
0.00
1.2
1.2
0.84
0.89
g/l
0.73
55
556
17
174
0.98
0.00
1.1
1.1
—
—
—
0
0
25
254
0.98
0.00
1.7
1.4
—
—
—
0
0
10
102
0.98
0.00
1.4
1.5
—
—
—
0
0
50
501
1.00
0.00
2.7
3.5
73.44
691.26
u/ml
1.43
42
431
11
105
1.05
0.00
1.3
1.4
7281.00
94121.62
e6/l
—
5
47
5
49
1.02
0.00
1.0
1.8
—
—
—
0
0
5
54
0.93
0.00
1.0
1.1
85.20
94.17
%
—
5
47
5
49
1.02
0.00
1.0
1.8
—
—
—
0
0
5
54
0.93
0.00
1.6
3.6
1.40
1.31
%
—
5
54
7
76
0.92
0.00
3.6
5.7
—
82.38
—
0
13
6
68
0.88
0.00
1.5
1.5
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.2
9.00
11.21
u/l
—
6
56
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
21.90
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
37.43
—
0
7
7
71
0.99
-0.00
1.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
7
69
1.01
-0.00
1.1
1.2
22.00
15.55
u/l
—
7
56
28
280
1.00
-0.00
1.3
1.6
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.9
30.67
32.24
umol/l
—
6
62
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
8.67
—
0
7
6
69
0.87
-0.00
1.3
1.2
86.00
409.22
u/l
—
6
63
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.9
42.80
40.76
g/l
—
5
52
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
3.27
—
0
9
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
2.88
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
1.17
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint E4_THYROIDITSUBAC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYROIDITSUBAC | 0.833 [0.71, 0.98] | 0.025 |
| Birth year | 0.993 [0.98, 1.0] | 0.139 |
During the follow-up period (1.1.1998 — 31.12.2019), 208 out of 4418 females with E4_THYROIDITSUBAC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYROIDITSUBAC | 0.597 [0.48, 0.74] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 91 out of 1239 males with E4_THYROIDITSUBAC died.
Mortality risk
Mortality risk for people of age
years, who have E4_THYROIDITSUBAC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.066% | 0.092% |
| 5 | 0.527% | 0.625% |
| 10 | 1.263% | 1.65% |
| 15 | 2.331% | 3.15% |
| 20 | 4.065% | 5.585% |
Relationships between endpoints
↥Index endpoint: E4_THYROIDITSUBAC – Subacute thyroiditis
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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