optic neuritis: Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.The conditionmay cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis , drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1833 |
4. Check minimum number of eventsNone |
1833 |
5. Include endpointsNone |
1833 |
6. Filter based on genotype QC (FinnGen only) |
1652 |
Control definitions (FinnGen only)
- Control exclude
- H7_OPTNERVE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H46-H48
- Name in latin
- Neuritis optica
Similar endpoints
↥List of similar endpoints to
Optic neuritis
based on the number of shared cases.
Similar with more cases:
- Disorders of optic nerve and visual pathways
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10403 | 6920 | 3413 |
| Only index persons | 9515 | 6484 | 3031 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.20 | 0.10 |
| Only index persons | 0.20 | 0.24 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 36.47 | 35.70 | 38.00 |
| Only index persons | 35.76 | 35.17 | 37.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1652 | 1247 | 405 |
| Unadjusted period prevalence (%) | 0.38 | 0.44 | 0.19 |
| Median age at first event (years) | 36.73 | 35.84 | 39.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1739
- Matched controls
- 17390
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AA27
ATC
[U] fingolimod
146.7
320.7
160
12
G35
ICD-10 Finland
Multiple sclerosis
199.1
307.7
899
93
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
174.5
307.7
627
56
TAB00
NOMESCO Finland
Lumbar puncture
15.7
307.7
463
392
N86
ICPC
Multiple sclerosis
145.4
307.7
301
25
H46
ICD-10 Finland
Optic neuritis
4503599627370496.0
307.7
1514
*
164
Kela drug reimbursment
Fingolimod
120.4
307.7
221
21
L03AB07
ATC
interferon beta-1a; parenteral
172.8
307.7
379
28
353
Kela drug reimbursment
Cladribine and fingolimod
124.0
307.7
198
18
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
12.6
307.7
668
822
N04BB01
ATC
amantadine; oral
36.1
307.7
213
67
L04AX07
ATC
dimethyl fumarate; oral
102.1
307.7
215
24
XCK00
NOMESCO Finland
Perimetry
23.0
307.7
527
323
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
66.6
307.7
266
47
L04AA31
ATC
[U] teriflunomide
154.9
307.7
168
12
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
201.4
307.7
678
55
L03AX13
ATC
glatiramer acetate; parenteral
131.5
307.7
286
26
109
Kela drug reimbursment
Multiple sclerosis
203.9
307.7
747
64
L03AB08
ATC
interferon beta-1b; parenteral
134.7
294.4
148
12
N07XX09
ATC
[U] dimethyl fumarate
100.3
250.8
130
14
XCD10
NOMESCO Finland
Electrophysiological examination of eye
18.3
235.9
195
119
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
12.2
226.9
240
225
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.0
215.8
635
1781
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
15.1
200.6
183
134
M03BX01
ATC
baclofen; systemic
14.6
196.4
183
139
2AB04, ,
NOMESCO Finland
78.1
179.2
96
13
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
11.0
177.0
198
200
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
36.3
168.8
106
31
H53.1
ICD-10 Finland
Subjective visual disturbances
6.0
161.3
323
636
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.1
158.3
400
967
XA800
NOMESCO Finland
Neuropsychological investigation
7.7
150.1
227
334
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.3
148.4
348
787
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
5.3
136.8
310
678
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
15.4
136.8
122
85
XKD06
NOMESCO Finland
Physiologic investigation of micturition
10.4
129.2
149
156
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
+∞
123.4
117
*
36703
ICD-8 Finland
Inflammation of optic nerve and retina, Neuritis optica, retrobulbaris
+∞
122.4
116
*
N06BA07
ATC
modafinil; oral
28.9
118.9
80
29
H53.4
ICD-10 Finland
Visual field defects
11.7
115.4
121
110
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.4
103.4
294
766
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
10.2
97.8
113
118
H47.2
ICD-10 Finland
Optic atrophy
+∞
93.6
89
*
G04BD09
ATC
trospium; oral
10.0
90.9
106
112
XKD00
NOMESCO Finland
Uroflowmetry
4.0
87.5
279
787
ZX120
NOMESCO Finland
Intravenous
4.0
86.8
278
786
H48.1*G35
ICD-10 Finland
Retrobulbar neuritis in multiple sclerosis
+∞
84.0
80
*
F02.89*G35
ICD-10 Finland
Dementia in multiple sclerosis
220.5
82.1
84
*
L04AG12
ATC
ofatumumab; parenteral
280.1
79.2
80
*
H47.1
ICD-10 Finland
Papilloedema, unspecified
803.7
79.0
77
*
H57.1
ICD-10 Finland
Ocular pain
4.9
77.2
184
413
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
16.4
76.4
65
41
3773B
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic neuritis[NEURITIS RETROBULBARIS]
+∞
74.5
71
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
8.3
74.2
100
127
XCK10
NOMESCO Finland
Photography of fundus of eye
4.0
74.0
232
643
CS494
NOMESCO Finland
Other visual field testing
7.9
72.2
101
134
H53.9
ICD-10 Finland
Visual disturbance, unspecified
5.4
71.0
146
288
G04BD12
ATC
mirabegron; oral
3.5
67.8
271
883
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
14.9
65.8
59
41
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
11.6
65.1
68
61
G36.0
ICD-10 Finland
Neuromyelitis optica [Devic]
334.2
64.9
65
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
10.5
64.7
72
71
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.3
63.5
176
444
XKC03
NOMESCO Finland
Water cystometry
6.4
63.3
108
178
Z3231
NOMESCO Finland
Registered nurse
2.5
63.1
576
2908
L04AK02
ATC
teriflunomide; oral
88.5
61.4
68
8
UKC02
NOMESCO Finland
Cystoscopy
3.1
61.1
291
1051
R1250
NOMESCO Finland
Evaluation of functional capability
6.2
61.1
107
181
L03AB13
ATC
peginterferon beta-1a; parenteral
608.5
60.1
59
*
L04AE01
ATC
fingolimod; oral
307.4
58.7
59
*
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
8.1
57.7
79
102
3400A
ICD-9 Finland
Multiple sclerosis[SCLEROSIS MULTIPLEX (DISSEMINATA)]
203.4
57.4
59
*
N03AX12
ATC
[U] gabapentin; oral
2.7
57.3
377
1618
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
14.3
54.6
50
36
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
22.7
54.5
40
18
G36.9
ICD-10 Finland
Acute disseminated demyelination, unspecified
77.8
53.3
60
8
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.3
53.1
219
723
H02AB04
ATC
methylprednisolone; systemic
2.7
52.9
342
1450
L04AA40
ATC
cladribine; oral
115.7
52.1
56
5
TKC22
NOMESCO Finland
Catheterisation instruction
7.8
51.2
72
96
R20.2
ICD-10 Finland
Paraesthesia of skin
3.1
50.1
227
792
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
12.2
49.8
50
42
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.6
48.6
175
529
36702
ICD-8 Finland
Inflammation of optic nerve and retina, Neuritis optica. Papillitis
+∞
48.1
46
*
G04BD04
ATC
oxybutynin; oral, transdermal
4.2
47.6
135
345
N03AE01
ATC
clonazepam; systemic
3.7
47.2
157
450
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
46.6
187
605
4AA23, ,
NOMESCO Finland
87.6
46.1
51
6
L04AA52
ATC
[U] ofatumumab; parenteral
459.4
45.5
45
*
G04BD08
ATC
solifenacin; oral
3.8
44.9
145
407
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
11.2
43.4
46
42
H53.2
ICD-10 Finland
Diplopia
4.8
43.4
101
221
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
4.8
40.3
93
202
3773A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic neuritis[PAPILLITIS OPTICA]
+∞
39.7
38
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.7
39.7
133
382
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.9
39.6
89
189
R4150
NOMESCO Finland
Neuropsychological rehabilitation
8.4
38.2
50
61
G04BD07
ATC
tolterodine; oral
4.1
38.1
109
280
R33
ICD-10 Finland
Retention of urine
3.5
37.2
132
394
N03AX16
ATC
[U] pregabalin
2.1
35.9
436
2392
Z3226
NOMESCO Finland
Physiotherapist
2.2
35.8
357
1813
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
35.0
281
1302
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.1
33.9
147
497
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
7.4
33.6
49
68
TKC20
NOMESCO Finland
Catheterisation of bladder
3.4
33.5
128
400
L28
ICPC
Limited function/disability (L)
2.2
32.8
315
1572
A02BC02
ATC
pantoprazole; systemic
1.9
31.7
1201
9429
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
48.5
31.6
38
8
N02BF01
ATC
gabapentin; oral
2.4
31.5
238
1070
Z2445
NOMESCO Finland
Psychologist
3.3
31.1
120
377
34099
ICD-8 Finland
Multiple sclerosis
162.9
30.8
32
*
L04AX01
ATC
azathioprine; systemic
3.4
30.4
113
347
N28
ICPC
Limited function/disability (N)
6.2
29.8
51
84
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
45.9
29.7
36
8
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.3
29.7
50
81
SPAT1229
SPAT
Assessment of need for aid
3.1
28.6
129
445
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
28.6
312
1630
C10AC01
ATC
colestyramine; oral
4.2
28.4
78
194
N05CF01
ATC
zopiclone; oral
1.8
28.3
548
3482
XKD03
NOMESCO Finland
Urethral pressure profilometry
5.1
27.1
58
118
R35
ICD-10 Finland
Polyuria
2.9
27.1
135
493
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
5.2
26.9
56
111
H53.8
ICD-10 Finland
Other visual disturbances
5.5
26.7
52
97
G04BD11
ATC
fesoterodine; oral
5.0
26.6
58
120
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
6.1
25.2
44
74
J01EA01
ATC
trimethoprim; systemic
1.8
25.1
494
3134
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.8
24.3
38
57
R4110
NOMESCO Finland
Physiotherapy
1.8
24.3
476
3011
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
9.0
24.2
30
34
N06AX16
ATC
venlafaxine; oral
2.0
24.1
331
1869
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
23.8
722
5151
H47.3
ICD-10 Finland
Other disorders of optic disc
243.2
23.7
24
*
AA1AD
NOMESCO Finland
CT of head and brain
1.8
23.6
425
2616
H02AB06
ATC
prednisolone; systemic
1.7
23.6
823
6088
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
8.1
23.1
31
39
H02AB07
ATC
prednisone; oral
2.1
22.6
247
1283
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
7.4
22.1
32
44
F05
ICPC
Visual disturbance other
3.4
22.0
82
252
G50.0
ICD-10 Finland
Trigeminal neuralgia
4.3
21.5
55
130
G04CA02
ATC
tamsulosin; oral
2.1
21.1
227
1171
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
20.9
231
1203
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.5
20.9
135
562
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
20.2
164
756
R5110, ,
SPAT
2.4
20.2
148
653
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
27.4
20.0
27
10
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
7.7
20.0
28
37
N03AF01
ATC
carbamazepine; oral, rectal
2.8
19.8
102
379
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
15.5
19.8
32
21
ZXA10
NOMESCO Finland
Bilateral
1.9
19.7
290
1668
R42
ICD-10 Finland
Dizziness and giddiness
1.8
19.6
376
2342
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
19.6
254
1399
RF120, ,
NOMESCO Finland
5.8
19.3
35
61
U13
ICPC
Bladder symptom/complaint other
3.5
18.9
66
195
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.9
18.6
90
323
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
7.9
18.3
25
32
R51.80
ICD-10 Finland
Headache
1.8
18.2
348
2161
N99
ICPC
Neurological disease other
5.2
17.9
37
73
A28
ICPC
Limited function/disability NOS
2.0
17.8
219
1184
N03AF02
ATC
oxcarbazepine; oral
3.1
17.7
77
260
Z2446
NOMESCO Finland
Social worker
2.3
17.6
134
600
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
5.0
17.6
38
78
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
17.4
664
4911
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
5.7
17.3
32
57
R4120
NOMESCO Finland
Occupational therapy
2.3
17.2
129
575
G81.9
ICD-10 Finland
Hemiplegia, unspecified
5.6
17.0
32
58
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
16.9
145
684
N29
ICPC
Neurological sympt/complt other
4.0
16.9
48
123
Z2221
NOMESCO Finland
Medical doctor
1.6
16.9
494
3427
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
16.1
482
3357
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
16.0
346
2217
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
15.9
222
1250
M03BX02
ATC
tizanidine; oral
1.5
15.8
1121
9411
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.7
15.7
84
318
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.5
15.6
54
159
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
15.5
198
1083
N06AA09
ATC
amitriptyline; systemic
2.1
15.4
156
785
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
11.4
15.3
28
25
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
14.9
678
5165
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.6
14.8
28
51
N30.0
ICD-10 Finland
Acute cystitis
1.7
14.6
325
2093
H48.1
ICD-10 Finland
Retrobulbar neuritis in diseases classified elsewhere
+∞
14.6
14
*
H51.2
ICD-10 Finland
Internuclear ophthalmoplegia
151.2
14.5
15
*
XCH00
NOMESCO Finland
Eye pressure measurement
2.7
14.5
78
297
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
14.4
461
3246
N02AX02
ATC
tramadol; systemic, rectal
1.5
14.3
655
4983
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.4
14.3
35
80
G04CA01
ATC
alfuzosin; oral
2.2
14.2
126
602
J01MA02
ATC
ciprofloxacin; systemic
1.5
14.2
577
4281
OAB50, ,
SPAT
2.1
14.1
133
651
U07
ICPC
Urine symptom/complaint other
2.1
14.0
142
715
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
14.0
205
1171
H30.2
ICD-10 Finland
Posterior cyclitis
12.8
13.9
24
19
R39.1
ICD-10 Finland
Other difficulties with micturition
3.3
13.6
51
158
36709
ICD-8 Finland
Inflammation of optic nerve and retina, Unspecified
+∞
13.6
13
*
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.6
13.4
43
120
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
9.4
13.0
26
28
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
28.6
13.0
17
6
U05
ICPC
Urination problems other
2.5
12.9
81
333
SPAT1216
SPAT
Assessment of functional ability
1.8
12.7
193
1114
L04AX09
ATC
diroximel fumarate; oral
70.4
12.6
14
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
12.5
188
1081
N03AX09
ATC
lamotrigine; oral
2.1
12.5
119
585
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
3.4
12.4
43
127
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.5
12.1
77
319
N06AB04
ATC
citalopram; systemic
1.6
12.0
351
2408
H54.7
ICD-10 Finland
Unspecified visual loss
8.7
12.0
25
29
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.2
12.0
46
145
RF420, ,
NOMESCO Finland
4.0
11.9
33
83
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
11.9
412
2933
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
11.9
536
4032
N06AX21
ATC
duloxetine; oral
1.7
11.7
227
1404
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
11.7
327
2219
J01CA08
ATC
pivmecillinam; oral
1.4
11.5
770
6224
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
11.5
151
832
H54.0
ICD-10 Finland
Blindness, binocular
120.8
11.4
12
*
G51.0
ICD-10 Finland
Bell palsy
3.0
11.4
51
176
N30.9
ICD-10 Finland
Cystitis, unspecified
2.0
11.4
122
627
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
11.3
191
1136
R50.9
ICD-10 Finland
Fever, unspecified
1.6
11.3
256
1649
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.3
11.3
29
69
J01AA02
ATC
doxycycline; systemic
1.5
11.2
1276
11327
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
5.0
11.2
24
49
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
11.2
394
2811
A02BC01
ATC
omeprazole; systemic
1.5
11.1
406
2923
RS221, ,
NOMESCO Finland
3.8
11.0
33
88
N18
ICPC
Paralysis/weakness
3.9
10.9
32
84
U08
ICPC
Urinary retention
4.2
10.8
28
67
G97.1
ICD-10 Finland
Other reaction to spinal and lumbar puncture
17.9
10.7
16
9
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
10.7
99
482
L01BB04
ATC
cladribine; systemic
60.4
10.6
12
*
U04
ICPC
Incontinence urine
2.3
10.6
83
377
S01EC01
ATC
acetazolamide; systemic
3.5
10.6
36
105
A04
ICPC
Weakness/tiredness general
1.6
10.6
273
1815
A06AD11
ATC
lactulose; oral
1.8
10.4
177
1055
H54.4
ICD-10 Finland
Blindness, monocular
12.1
10.3
18
15
WW400
NOMESCO Finland
Plasmaferesis
18.9
10.3
15
8
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.1
10.2
41
133
U02
ICPC
Urinary frequency/urgency
1.6
10.0
248
1631
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
9.9
144
819
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
9.8
366
2635
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
9.8
85
403
F01
ICPC
Eye pain
2.4
9.8
64
269
G04BD01
ATC
emepronium; systemic
5.3
9.6
19
36
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
4.3
9.6
24
56
WX892
NOMESCO Finland
Monitored bed care
2.0
9.6
104
537
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.1
9.5
39
128
A02BA02
ATC
ranitidine; systemic
1.6
9.5
255
1708
ABD40
NOMESCO Finland
Implantation of spinal injection device
100.6
9.4
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
9.4
379
2769
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.8
9.2
45
164
M05BA04
ATC
alendronic acid; oral
2.0
9.1
97
497
U28
ICPC
Limited function/disability (U)
5.0
9.1
19
38
D12
ICPC
Constipation
2.5
9.1
57
235
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
4.6
9.1
21
46
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.0
395
2929
A02BC03
ATC
lansoprazole; oral
1.4
9.0
401
2983
PAW37
NOMESCO Finland
Biopsy of temporal artery
10.1
9.0
17
17
R51.81
ICD-10 Finland
Facial pain NOS
2.5
9.0
53
212
N02BE01
ATC
paracetamol; systemic, rectal
1.5
9.0
1495
13885
RF410, ,
NOMESCO Finland
3.9
9.0
26
68
H53
ICD-10 Finland
Visual disturbances
3.9
9.0
26
68
N07AA03
ATC
distigmine; systemic
24.1
8.9
12
5
N05BA01
ATC
diazepam; systemic, rectal
1.6
8.9
194
1237
U29
ICPC
Urinary symptom/complaint other
2.5
8.8
52
208
NA7CM
NOMESCO Finland
Spine and spinal cord extensive MRI examination with 3 Tesla magnet
50.2
8.7
10
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
8.6
150
900
H52.1
ICD-10 Finland
Myopia
2.1
8.6
84
418
Z50.1
ICD-10 Finland
Other physical therapy
2.1
8.6
81
398
G93.2
ICD-10 Finland
Benign intracranial hypertension
27.7
8.5
11
*
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.9
8.5
113
626
R15
ICD-10 Finland
Faecal incontinence
2.7
8.4
45
172
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.3
8.4
62
276
Z71.8
ICD-10 Finland
Other specified counselling
1.4
8.4
602
4855
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
3.8
8.4
25
67
G37.0
ICD-10 Finland
Diffuse sclerosis
+∞
8.3
8
*
3773X
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic neuritis[NEURITIS OPTICA ALIA SEU NUD]
+∞
8.3
8
*
NA1BM
NOMESCO Finland
Cervical spine MRI examination with 3 Tesla magnet
10.8
8.3
15
14
Z43.5
ICD-10 Finland
Attention to cystostomy
10.8
8.3
15
14
6BA02, ,
NOMESCO Finland
9.5
8.3
16
17
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
3.5
8.3
27
77
ZXE00
NOMESCO Finland
One hour or less
1.4
8.2
612
4958
H25.8
ICD-10 Finland
Other senile cataract
1.9
8.2
95
503
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
8.2
182
1166
H54.5
ICD-10 Finland
Severe visual impairment, monocular
7.6
8.2
18
24
S06.0
ICD-10 Finland
Concussion
1.6
8.1
175
1111
H02AB09
ATC
hydrocortisone; systemic
2.6
8.1
45
175
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.1
8.1
32
103
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
8.1
81
407
4AA36, ,
NOMESCO Finland
33.5
8.1
10
*
F43.21
ICD-10 Finland
Adaptation disorder with prolonged depression
3.8
8.1
24
64
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
8.0
148
904
J01MA12
ATC
levofloxacin; systemic
1.5
8.0
239
1640
J01XE01
ATC
nitrofurantoin; oral
3.0
7.9
34
115
ZXY02
NOMESCO Finland
Neuropsychologist
4.7
7.9
18
39
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
7.8
86
448
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
7.0
7.8
18
26
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.7
454
3534
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.3
7.7
56
247
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
7.7
116
667
KCW98
NOMESCO Finland
Other transluminal endoscopic operation on bladder
45.2
7.7
9
*
W19
ICD-10 Finland
Unspecified fall
1.7
7.6
144
884
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
7.6
245
1706
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.0
7.6
75
375
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
7.5
191
1262
NA1CM
NOMESCO Finland
Cervical spine extensive MRI examination with 3 Tesla magnet
10.1
7.5
14
14
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
7.5
161
1023
G37.3
ICD-10 Finland
Acute transverse myelitis in demyelinating disease of central nervous system
80.4
7.4
8
*
G04BD10
ATC
darifenacin; oral
7.7
7.4
16
21
U71
ICPC
Cystitis/urinary infection other
1.8
7.3
117
686
RS222, ,
NOMESCO Finland
3.6
7.3
23
64
34109
ICD-8 Finland
Other demyelinating diseases of central nervous system, Unspecified
+∞
7.3
7
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
7.3
491
3903
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.0
7.3
73
368
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
7.2
130
788
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.7
7.2
135
827
SPAT1262
SPAT
Handing over of treatment supplies
1.5
7.2
212
1448
R31
ICD-10 Finland
Unspecified haematuria
1.8
7.2
105
599
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
4.5
7.2
17
38
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
7.1
931
8132
N05CD07
ATC
temazepam; oral
1.7
7.1
129
784
S29
ICPC
Skin symptom/complaint other
1.4
7.1
303
2229
N06AX11
ATC
mirtazapine; oral
1.3
7.1
541
4381
J05AB01
ATC
aciclovir; systemic
1.4
6.9
358
2722
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.1
6.9
66
326
G50.1
ICD-10 Finland
Atypical facial pain
2.7
6.9
36
136
C03CA01
ATC
furosemide; systemic
1.4
6.9
284
2075
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
8.3
6.8
14
17
S01EA05
ATC
brimonidine; ophthalmic
3.0
6.8
29
98
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.0
6.8
29
98
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
11.0
6.8
12
11
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
9.3
6.8
13
14
U01
ICPC
Dysuria/painful urination
1.7
6.8
136
849
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
5.7
6.8
18
32
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.7
6.8
128
787
G37.8
ICD-10 Finland
Other specified demyelinating diseases of central nervous system
22.6
6.7
9
*
XCD20
NOMESCO Finland
Photoangiography of eye
3.7
6.6
20
54
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.6
662
5556
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
6.6
114
684
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
12.3
6.6
11
9
R02
ICPC
Shortness of breath/dyspnoea
1.5
6.6
189
1285
R4110, ,
SPAT
1.5
6.5
189
1287
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
6.5
316
2377
R60.0
ICD-10 Finland
Localized oedema
1.6
6.4
165
1093
SPAT1301
SPAT
No procedures
1.3
6.4
425
3362
G44.0
ICD-10 Finland
Cluster headache syndrome
3.1
6.4
26
86
R52.9
ICD-10 Finland
Pain, unspecified
1.6
6.4
162
1072
H34.2
ICD-10 Finland
Other retinal artery occlusions
8.2
6.3
13
16
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
8.2
6.3
13
16
H34.1
ICD-10 Finland
Central retinal artery occlusion
11.1
6.3
11
10
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
2.8
6.3
31
114
ZXD05
NOMESCO Finland
Urgent procedure
1.3
6.3
480
3874
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.3
557
4591
F43.29
ICD-10 Finland
Adaptation disorder UNS
2.1
6.3
54
257
SPAT1167
SPAT
Insertion of urinary catheter
2.7
6.3
32
120
G36.8
ICD-10 Finland
Other specified acute disseminated demyelination
+∞
6.3
6
*
S82.1
ICD-10 Finland
Fracture of upper end of tibia
2.7
6.2
33
126
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
1.9
6.2
69
361
N02BF02
ATC
pregabalin; oral
1.7
6.2
108
650
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
4.0
6.2
17
43
R13
ICD-10 Finland
Dysphagia
1.7
6.2
99
582
N04BC05
ATC
pramipexole; oral
1.7
6.1
97
569
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
3.8
6.1
18
48
G44.2
ICD-10 Finland
Tension-type headache
1.4
6.1
247
1798
N30
ICD-10 Finland
Cystitis
1.6
6.1
154
1018
R32
ICD-10 Finland
Unspecified urinary incontinence
2.4
6.1
38
158
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.0
673
5715
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
249
133
21.68
322.40
1.1
1.1
—
—
—
0
0
280
12
277.92
307.65
1.3
1.0
—
—
—
0
0
258
141
21.31
307.65
1.2
1.2
42.58
35.72
mg/l
1.04
202
114
188
22
95.69
307.65
3.2
1.9
—
—
—
0
0
254
136
21.70
307.65
1.1
1.0
206.98
217.22
mg/l
0.42
219
116
212
115
20.86
271.75
1.3
1.2
0.80
0.57
ratio
5.32
98
67
309
400
9.18
230.82
1.2
1.4
407.98
477.24
mg/l
2.32
291
382
533
1237
5.77
227.48
4.0
2.8
9.85
10.60
g/l
4.85
494
1164
200
156
14.36
211.67
1.1
1.1
—
—
—
0
0
271
352
8.94
200.97
1.3
1.5
8.88
14.42
e6/l
0.79
197
272
271
357
8.81
198.59
1.3
1.5
441.80
1798.38
e6/l
0.85
207
285
167
107
17.16
196.62
1.1
1.0
0.99
1.06
u/l
0.76
59
51
329
552
7.12
194.49
1.8
1.5
0.06
0.20
iu/ml
0.59
22
91
169
125
14.87
183.99
3.6
2.3
1314.24
1345.50
e6/l
0.11
144
115
143
94
16.49
165.77
3.8
2.4
238.74
218.35
e6/l
0.43
119
86
244
362
7.68
160.48
1.2
1.3
3.56
3.67
mmol/l
0.75
227
345
135
91
16.00
154.30
3.6
2.3
473.93
608.37
e6/l
0.68
107
79
138
7
213.93
134.83
1.2
1.1
—
—
—
0
0
89
32
29.26
132.74
1.1
1.0
4.90
5.46
mg/g
0.56
84
32
125
99
13.53
130.20
1.1
1.1
1683.55
1569.14
miu/ml
0.38
125
99
403
1167
4.19
124.51
2.7
2.4
22.04
20.70
au/ml
0.12
28
156
380
1086
4.20
119.15
1.5
1.3
69.07
40.18
au/ml
—
8
68
114
97
12.51
113.47
3.2
2.2
—
—
—
0
0
341
969
4.13
106.99
3.6
1.7
1.08
1.36
g/l
4.17
333
911
1280
8009
3.27
105.51
13.6
6.4
0.56
0.55
e9/l
1.40
1173
7020
1281
8020
3.27
105.46
13.6
6.4
0.04
0.04
e9/l
0.06
1172
7028
1232
7590
3.14
103.40
13.3
6.4
26.60
28.81
%
11.99
1199
7257
1295
8212
3.26
103.13
13.6
6.4
1.70
1.94
e9/l
15.15
1199
7382
1219
7487
3.10
102.44
13.0
6.3
58.97
56.87
%
9.50
1194
7193
1294
8298
3.19
99.04
13.7
6.7
0.19
0.18
e9/l
0.37
1192
7384
1329
8886
3.10
89.66
14.4
9.5
3.84
4.02
e9/l
2.58
1221
7823
611
3077
2.52
68.20
4.0
2.5
4.80
7.16
e6/l
5.64
573
2799
776
4514
2.30
60.90
5.4
3.1
19.86
87.70
e6/l
2.33
651
3372
882
5451
2.25
59.30
6.4
3.7
115.06
86.82
e6/l
0.40
689
3641
686
3887
2.26
56.25
5.2
3.0
0.13
0.37
e6/l
7.95
562
2776
1034
6917
2.22
55.89
16.8
10.3
0.00
0.00
e9/l
0.96
897
5682
68
78
9.03
54.62
1.3
1.4
78.22
79.90
%
—
9
10
1044
7082
2.19
53.51
2.9
2.5
85.92
75.12
nmol/l
21.55
990
6602
213
693
3.36
52.84
1.9
2.1
38.61
40.08
u/l
0.54
208
638
936
6146
2.13
51.40
4.7
4.8
37.15
36.64
g/l
2.18
897
5812
1143
8303
2.10
45.50
6.0
3.6
0.00
0.19
estimate
0.53
296
1632
1138
8268
2.09
45.08
6.0
3.6
4.58
6.48
estimate
0.15
304
1722
1129
8184
2.08
44.93
6.0
3.6
0.00
0.00
estimate
0.38
297
1707
50
50
10.27
44.38
1.2
1.1
19.44
15.00
%
—
9
6
1301
9973
2.21
44.36
8.5
4.2
308.24
2038.26
e6/l
1.43
21
119
1108
8348
1.90
34.96
4.8
4.8
6.24
6.45
mmol/l
3.82
1057
7774
43
50
8.79
34.10
1.2
1.1
109.28
47.55
ng/l
0.48
18
11
55
91
6.21
32.00
4.3
3.1
51.92
44.38
%
2.11
39
49
1018
7588
1.82
31.86
6.2
6.1
10.24
10.69
umol/l
0.56
976
7248
1366
11248
2.00
30.44
8.6
7.8
77.00
75.36
u/l
0.38
1311
10741
409
2359
1.96
28.46
4.8
2.6
0.85
1.25
e6/l
0.89
234
1174
380
2189
1.94
26.30
4.9
2.8
3.22
3.37
e6/l
0.12
200
1003
122
439
2.91
25.11
1.7
2.2
9.83
11.27
mg/l
1.67
116
415
348
1990
1.94
24.44
2.2
2.1
29.34
29.22
s
0.18
336
1931
154
670
2.42
21.67
1.5
1.4
—
—
—
0
0
539
3669
1.68
20.55
4.7
3.8
96.41
94.51
%
1.19
531
3586
770
5783
1.59
19.48
9.4
10.7
1.12
1.16
inr
1.47
657
4775
679
4964
1.60
19.15
2.5
3.3
2.35
2.35
mmol/l
0.27
631
4588
619
4440
1.61
18.82
6.9
3.7
0.00
0.01
estimate
1.74
285
1619
1315
11283
1.68
18.55
4.7
4.2
10.66
10.24
mm/h
0.59
1244
10698
34
60
5.76
18.55
1.2
2.1
—
—
—
0
0
533
3712
1.63
18.15
2.2
1.5
2.06
2.25
g/l
2.35
381
2435
575
4171
1.57
16.09
2.3
2.1
119.81
183.32
u/l
2.69
548
3993
1634
15139
2.31
16.05
19.3
13.5
20.53
20.85
mg/l
0.15
1373
12327
1579
14447
2.01
15.97
17.1
12.2
91.37
88.45
ml/min/173m2
6.91
1466
13221
147
719
2.14
15.61
2.5
2.0
0.00
0.98
estimate
0.51
41
260
1620
14992
2.18
15.38
18.3
14.5
3.91
3.93
mmol/l
2.50
1594
14682
1617
14958
2.15
15.30
18.2
14.4
139.66
139.62
mmol/l
0.30
1596
14684
27
50
5.47
14.02
1.0
1.0
—
—
—
0
0
212
1223
1.84
14.00
2.9
2.2
5076.75
6228.06
u/l
0.17
55
503
176
965
1.92
13.60
1.9
2.8
68.38
67.55
g/l
0.82
167
905
24
20
12.15
13.59
1.0
1.1
—
—
—
0
0
841
6790
1.46
13.32
6.7
6.7
1.21
1.21
mmol/l
0.05
716
5923
758
6008
1.46
13.17
6.0
6.1
1.21
1.21
mmol/l
0.45
705
5604
624
4763
1.48
13.13
5.7
3.0
0.01
0.07
estimate
0.84
271
1391
47
143
3.35
12.91
1.2
1.7
—
—
—
0
0
86
365
2.43
12.79
2.3
3.0
1.83
2.00
index
0.13
46
199
32
79
4.11
11.87
1.1
1.1
—
—
—
0
0
785
6353
1.43
11.75
6.4
3.4
0.01
0.03
estimate
1.61
265
1426
26
55
4.78
11.67
1.1
1.2
—
—
—
0
0
1678
15955
2.47
11.53
22.6
16.2
70.02
71.46
umol/l
1.53
1669
15801
1271
11269
1.48
11.31
4.6
3.2
43.39
40.04
u/l
0.76
1219
10809
180
1077
1.75
10.45
4.6
2.4
0.23
0.41
e6/l
1.00
173
1024
682
5480
1.40
10.18
4.0
3.2
29.06
29.90
u/l
0.32
650
5215
19
36
5.33
9.64
1.2
1.1
—
—
—
0
0
19
36
5.33
9.64
1.2
1.1
—
—
—
0
0
627
5002
1.40
9.62
3.6
3.2
35.15
56.84
ng/l
0.60
383
2885
1668
15933
2.15
9.40
17.8
10.9
26.14
25.64
u/l
0.55
1642
15601
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
28
75
3.78
9.34
1.0
1.1
—
—
—
0
0
256
1763
1.53
8.41
3.0
2.6
6.18
7.10
umol/l
0.51
218
1527
131
780
1.73
7.75
2.1
2.0
6.46
8.11
iu/ml
0.21
27
189
7
0
+∞
7.29
1.4
0.0
—
—
—
0
0
213
1457
1.53
7.19
3.3
2.4
37.16
41.10
u/l
0.39
177
1220
17
38
4.51
7.18
1.2
1.1
—
—
—
0
0
307
2280
1.42
6.81
3.3
3.4
0.83
0.82
mmol/l
0.37
297
2180
56
263
2.17
6.71
1.3
1.3
180.00
271.00
titre
—
8
20
715
6079
1.30
6.45
2.1
2.0
98.65
98.10
pmol/l
0.11
378
3318
86
479
1.84
6.40
1.4
2.1
1.55
1.44
g/l
0.49
75
426
186
1271
1.52
6.31
2.5
2.3
0.22
0.22
g/l
0.04
178
1205
27
94
2.90
6.06
1.1
1.1
—
—
—
0
0
271
2015
1.41
5.93
2.5
2.4
22.66
23.50
%
0.48
251
1886
233
1690
1.44
5.85
4.9
5.8
1.04
1.03
mmol/l
0.09
212
1577
194
1364
1.48
5.73
3.0
4.7
221.90
244.81
u/l
1.68
183
1303
1411
13228
1.35
5.65
27.0
16.3
13.40
13.43
%
0.34
1402
13070
293
2229
1.38
5.59
2.5
2.3
2.40
2.40
g/l
0.03
272
2085
49
237
2.10
5.51
1.8
1.5
—
—
—
0
0
471
3857
1.30
5.44
1.7
1.6
18.95
20.34
nmol/l
1.48
404
3388
283
2153
1.38
5.39
2.0
1.9
—
—
—
0
0
26
96
2.73
5.28
1.4
1.1
—
—
—
0
0
32
132
2.45
5.22
1.1
1.5
—
—
—
0
0
1343
14207
0.76
5.22
3.8
3.9
1.25
1.25
mmol/l
0.03
1259
13428
65
355
1.86
5.20
2.2
1.6
—
—
—
0
0
558
4693
1.28
5.20
2.7
2.6
58.77
58.95
u/l
0.02
523
4402
16
36
4.48
5.05
1.3
1.1
—
—
—
0
0
1516
14432
1.39
5.04
6.3
5.6
1.76
1.80
mu/l
0.60
1446
13716
16
37
4.35
4.93
1.3
1.1
—
—
—
0
0
402
3262
1.30
4.91
2.7
3.0
854.97
915.29
ng/l
0.20
339
2718
307
2410
1.33
4.74
2.5
2.4
13.62
14.01
umol/l
0.38
288
2256
263
2018
1.36
4.73
1.8
1.7
1162.59
1177.92
nmol/l
0.10
198
1577
110
724
1.55
4.48
1.8
1.6
—
—
—
0
0
179
1304
1.42
4.40
3.6
2.9
—
—
—
0
0
10
17
5.91
4.13
1.2
1.0
—
—
—
0
0
445
3740
1.26
4.01
1.9
1.8
0.78
0.98
mg/l
2.11
333
2822
7
7
10.03
4.01
1.1
1.0
—
—
—
0
0
10
18
5.58
3.97
1.0
1.4
—
—
—
0
0
10
18
5.58
3.97
1.2
1.0
—
—
—
0
0
146
1050
1.43
3.87
4.4
3.4
1.22
1.23
mmol/l
0.72
134
904
205
1564
1.35
3.83
2.0
1.8
—
—
—
0
0
20
77
2.62
3.81
1.4
3.4
0.75
0.81
index
0.13
20
77
68
415
1.66
3.81
2.4
2.6
24.79
24.81
mmol/l
0.01
68
410
311
2534
1.28
3.61
3.4
3.4
747.69
381.28
ng/l
0.56
184
1621
48
271
1.79
3.55
1.3
1.7
—
—
—
0
0
8
13
6.18
3.50
1.0
1.2
—
—
—
0
0
137
994
1.41
3.48
1.7
1.7
—
—
—
0
0
25
113
2.23
3.42
1.9
3.1
23.30
12.86
index
0.84
20
77
144
1071
1.38
3.18
7.4
7.8
8.03
8.35
mmol/l
0.25
137
1036
1331
12645
1.22
3.17
5.1
4.7
14.60
14.47
pmol/l
1.17
1251
11907
209
1645
1.31
3.17
2.9
2.1
367.17
376.09
nmol/l
0.17
196
1538
458
3949
1.22
3.17
2.5
2.2
2.74
2.68
mg/l
0.22
403
3457
12
35
3.45
3.10
1.0
1.1
—
—
—
0
0
31
160
1.95
3.05
1.5
1.1
—
—
—
0
0
35
189
1.87
3.02
1.5
1.2
—
—
—
0
0
12
36
3.35
3.02
1.1
1.2
—
—
—
0
0
1445
14959
0.80
3.00
4.3
4.5
1.48
1.49
mmol/l
0.26
1352
14225
30
154
1.96
3.00
1.5
1.1
—
—
—
0
0
32
169
1.91
2.96
1.5
1.1
—
—
—
0
0
28
141
2.00
2.96
1.0
1.1
115.50
113.01
pmol/l
0.08
28
141
95
667
1.45
2.93
4.4
3.0
1.02
1.02
ratio
0.07
83
605
11
292
0.37
2.91
2.1
3.9
183.27
26.01
u/ml
0.70
11
284
31
163
1.92
2.91
1.5
1.1
—
—
—
0
0
31
163
1.92
2.91
1.5
1.1
—
—
—
0
0
41
236
1.76
2.90
1.3
1.3
—
—
—
0
0
41
236
1.76
2.90
1.3
1.3
—
—
—
0
0
86
595
1.47
2.87
1.2
1.3
13.16
28.01
u/ml
—
5
31
58
368
1.60
2.86
2.4
2.9
—
—
—
0
0
54
339
1.61
2.79
3.6
5.7
1204.57
261.98
iu/ml
—
7
40
1691
16629
1.61
2.76
32.0
20.5
90.89
90.51
fl
3.41
1683
16522
27
138
1.97
2.75
1.1
1.2
—
42.29
—
0
7
190
1507
1.29
2.74
2.0
1.8
—
—
—
0
0
1691
16632
1.61
2.72
32.4
20.9
40.50
40.71
%
0.32
1682
16517
1691
16633
1.60
2.70
32.0
20.6
4.49
4.51
e12/l
0.98
1672
16359
1691
16636
1.60
2.66
32.1
20.6
6.61
6.71
e9/l
1.03
1670
16353
1690
16625
1.59
2.64
32.1
20.6
262.63
260.95
e9/l
0.53
1675
16389
1691
16640
1.59
2.60
32.3
20.7
135.04
135.30
g/l
0.36
1682
16529
42
252
1.68
2.60
2.7
2.2
16.04
16.52
%
0.48
42
246
78
541
1.46
2.59
4.0
6.0
1.64
1.55
%
0.35
73
511
74
508
1.48
2.59
1.2
1.1
5.01
4.00
—
9
81
8
20
4.01
2.57
1.3
1.1
—
—
—
0
0
12
42
2.87
2.54
1.2
2.1
39.95
41.87
g/l
0.41
12
42
53
342
1.57
2.48
3.1
3.7
37.37
36.31
mg/l
0.04
44
295
21
102
2.07
2.47
1.5
1.3
70.57
72.10
umol/l
0.13
21
102
7
16
4.39
2.47
1.0
1.3
—
—
—
0
0
54
351
1.56
2.45
1.7
2.3
0.00
0.00
g/l
-0.00
49
316
37
219
1.70
2.42
1.6
1.4
—
—
—
0
0
97
710
1.39
2.42
1.5
1.5
—
—
—
0
0
6
12
5.01
2.40
1.3
1.2
—
—
—
0
0
52
342
1.54
2.26
3.2
3.7
42.75
61.26
mg/l
0.49
43
296
149
1177
1.29
2.25
3.7
3.7
4.54
4.57
pmol/l
0.19
134
1063
1458
15004
0.83
2.24
4.4
4.6
4.73
4.75
mmol/l
0.40
1372
14333
128
991
1.31
2.24
2.4
1.7
355.46
294.23
mu/l
1.03
113
897
5
9
5.57
2.21
1.4
1.1
—
—
—
0
0
77
555
1.41
2.13
1.1
1.3
3.39
9.71
u/ml
—
10
92
13
55
2.37
2.12
2.1
3.1
24.70
30.66
umol/l
—
8
43
44
665
0.65
2.10
1.8
1.8
—
—
—
0
0
410
3623
1.17
2.09
5.9
3.6
1.02
1.44
kg/l
0.50
281
2409
311
2690
1.19
2.04
2.3
2.6
2.43
2.43
mmol/l
0.02
279
2411
76
553
1.39
2.01
1.1
1.3
1.96
2.38
u/ml
—
7
58
46
305
1.52
1.96
1.3
1.2
6.00
4.14
u/ml
0.21
21
104
125
1572
0.78
1.96
1.5
1.6
1126.19
1020.75
mu/l
0.55
102
1298
328
2866
1.18
1.91
1.8
1.7
432.98
36829892.48
pmol/l
3.32
288
2498
1476
15135
0.84
1.90
4.8
5.0
2.78
2.82
mmol/l
0.78
1378
14406
58
813
0.70
1.90
1.5
1.5
—
—
—
0
0
164
1341
1.25
1.90
6.5
8.9
0.60
0.87
mmol/l
0.43
125
1099
5
12
4.18
1.82
1.0
1.2
1.60
7.75
u/l
—
5
12
481
4344
1.15
1.81
1.4
1.3
1.42
1.61
u/ml
0.14
134
1244
44
295
1.50
1.81
1.5
1.4
—
—
—
0
0
53
747
0.70
1.80
1.6
1.6
—
—
—
0
0
108
845
1.30
1.80
1.2
1.3
186.58
226.74
miu/ml
0.53
36
428
9
35
2.58
1.80
1.6
3.6
4.64
4.84
kpa
—
9
35
9
35
2.58
1.80
1.6
3.6
9.53
10.56
kpa
—
9
35
283
2457
1.18
1.78
2.3
2.6
116.70
106.02
ug/g
0.22
212
1981
6
18
3.34
1.74
1.2
1.2
—
—
—
0
0
90
690
1.32
1.74
3.7
3.0
1.84
1.63
mmol/l
0.18
67
501
197
2325
0.83
1.74
1.8
1.9
3.30
3.44
ratio
0.95
141
1726
38
566
0.66
1.74
1.6
1.5
45.61
60.03
ug/l
2.20
38
566
161
1328
1.23
1.74
1.5
1.3
344.37
212.56
u/ml
0.36
148
1237
5
13
3.85
1.71
1.0
1.2
—
—
—
0
0
21
119
1.77
1.66
1.1
1.1
2.37
0.54
nmol/l
—
6
18
164
1364
1.22
1.65
6.6
8.8
12.98
12.85
kpa
0.11
157
1317
164
1364
1.22
1.65
6.6
8.8
5.01
5.09
kpa
0.65
157
1315
418
3764
1.15
1.64
1.6
1.5
—
—
—
0
0
5
14
3.58
1.61
1.0
1.1
—
—
—
0
0
44
304
1.46
1.59
1.3
1.2
5.77
4.91
u/ml
0.10
22
135
19
107
1.78
1.55
1.2
1.3
5.95
6.51
u/l
0.25
13
92
18
101
1.79
1.49
2.2
2.2
4.30
2.24
u/field
—
10
63
144
1197
1.22
1.48
6.7
9.4
96.65
95.97
%
1.58
138
1164
5
16
3.13
1.44
1.2
1.3
—
—
—
0
0
57
760
0.74
1.43
1.7
1.7
3.29
3.74
mg/l
0.24
34
554
67
509
1.33
1.43
2.2
1.9
—
—
—
0
0
9
40
2.26
1.40
1.2
1.2
—
—
—
0
0
14
74
1.90
1.39
1.1
1.1
114.57
206.48
iu/ml
1.65
14
74
81
1024
0.78
1.39
1.5
1.5
—
—
—
0
0
47
339
1.40
1.38
1.5
1.4
—
—
—
0
0
61
460
1.34
1.37
2.0
1.8
—
—
—
0
0
34
232
1.47
1.34
1.2
1.9
—
1496.00
—
0
10
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
44
317
1.40
1.32
3.1
3.5
0.31
0.36
iu/ml
0.51
23
166
77
607
1.28
1.28
1.2
1.3
—
—
—
0
0
5
118
0.42
1.24
1.0
1.2
7.60
8.05
mm/h
—
5
118
66
842
0.78
1.24
1.0
1.1
1.58
1.55
g/l
0.45
66
842
29
417
0.69
1.18
1.2
1.2
—
—
—
0
0
62
481
1.30
1.18
1.2
1.2
40.47
43.90
u/ml
—
6
51
12
211
0.57
1.16
1.4
1.6
7.53
7.60
mmol/l
0.09
12
201
10
50
2.01
1.16
1.1
2.2
17.95
16.70
umol/l
—
10
50
22
142
1.56
1.14
2.0
1.7
52.75
52.25
%
0.02
12
93
7
31
2.26
1.10
1.4
1.2
—
—
—
0
0
12
66
1.82
1.09
1.5
1.5
81.20
94.56
%
—
5
39
8
41
1.96
1.09
10.4
4.4
—
—
—
0
0
84
1022
0.81
1.08
1.3
1.4
—
—
—
0
0
26
373
0.69
1.07
2.1
2.3
4.26
4.96
umol/l
0.26
16
283
23
153
1.51
1.06
1.5
1.3
—
—
titre
—
0
0
80
651
1.24
1.06
1.5
1.3
11.02
10.66
u/l
0.06
65
534
58
454
1.29
1.06
1.9
1.8
0.67
2.19
ug/l
1.47
53
409
171
1497
1.16
1.03
1.3
1.2
204.02
154.10
u/ml
0.58
62
603
69
853
0.80
1.03
1.4
1.5
1.18
1.15
ratio
0.09
33
505
69
853
0.80
1.03
1.4
1.5
1.03
0.95
ratio
0.68
33
505
69
853
0.80
1.03
1.4
1.5
1.23
1.19
ratio
0.09
34
508
12
68
1.77
1.00
1.4
1.2
86.20
93.28
%
—
5
40
41
309
1.33
0.99
2.5
2.8
1.00
0.94
nmol/l
0.20
34
264
41
309
1.33
0.99
1.6
1.6
265.50
354.96
mu/l
2.76
36
257
114
970
1.19
0.98
2.7
2.3
12.42
12.06
nmol/l
0.16
103
890
155
1769
0.86
0.98
1.5
1.6
3.37
3.49
mmol/l
0.71
104
1195
9
50
1.80
0.96
2.9
2.2
—
—
—
0
0
69
845
0.81
0.96
1.3
1.4
—
—
—
0
0
12
69
1.74
0.96
1.8
2.9
7.18
8.77
mmol/l
1.43
12
69
22
149
1.48
0.95
2.2
2.1
27.36
20.11
mg/l
0.29
11
65
13
77
1.69
0.95
1.1
1.5
95.15
168.35
mmol/24h
5.32
13
77
9
51
1.77
0.94
1.9
1.9
48.44
50.46
ug/l
—
9
51
18
117
1.54
0.93
1.5
1.5
—
—
—
0
0
22
151
1.46
0.90
1.1
1.0
—
—
—
0
0
76
914
0.82
0.90
1.4
1.5
64.60
59.42
ug/l
0.37
61
755
17
254
0.67
0.89
1.4
1.4
6.41
7.12
mmol/l
0.62
17
225
137
1196
1.16
0.89
4.8
3.4
1.72
1.80
mmol/l
0.09
124
1031
46
360
1.29
0.87
1.6
1.2
—
—
—
0
0
36
272
1.33
0.87
1.5
1.4
—
—
—
0
0
150
1699
0.87
0.87
2.0
1.9
—
—
—
0
0
15
96
1.57
0.84
1.5
1.5
—
—
—
0
0
16
106
1.51
0.79
1.0
1.1
—
—
—
0
0
13
199
0.65
0.78
1.1
1.1
—
—
—
0
0
1312
13380
0.92
0.77
26.2
16.9
332.17
332.45
g/l
0.58
1307
13301
82
696
1.19
0.77
1.6
1.7
—
—
—
0
0
1140
11687
0.93
0.77
3.7
3.6
—
—
—
0
0
11
67
1.65
0.75
1.5
1.3
—
—
—
0
0
67
797
0.83
0.74
1.0
1.1
0.48
0.63
ratio
—
8
81
391
3667
1.09
0.73
2.8
2.2
—
—
—
0
0
201
2206
0.90
0.72
1.9
1.8
1.55
1.42
%
1.40
186
1971
38
299
1.28
0.72
3.0
2.8
1.42
1.53
mmol/l
0.42
38
288
440
4151
1.08
0.72
1.8
1.7
—
—
—
0
0
11
68
1.62
0.71
1.5
1.3
—
—
—
0
0
306
2845
1.09
0.71
2.0
2.1
—
—
—
0
0
7
41
1.71
0.70
1.4
1.3
—
83.33
—
0
12
54
446
1.22
0.69
1.4
1.4
314.62
308.81
ug/g
0.06
31
246
751
7231
1.07
0.69
3.0
2.7
—
—
estimate
—
0
0
259
2394
1.10
0.68
5.2
4.8
2.17
2.29
ug/l
0.15
232
2178
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
7
42
1.67
0.68
1.4
1.3
—
72.17
—
0
12
336
3143
1.09
0.68
2.1
2.2
—
—
—
0
0
7
43
1.63
0.67
1.1
1.4
—
—
—
0
0
38
303
1.26
0.66
3.8
3.6
2.09
2.48
ratio
0.16
17
174
43
349
1.24
0.65
1.4
1.4
—
—
—
0
0
63
533
1.19
0.64
2.1
2.2
5.47
4.04
iu/l
0.29
22
233
82
710
1.16
0.64
6.3
7.8
23.88
24.33
mmol/l
0.51
77
680
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
8
51
1.57
0.60
3.8
2.5
—
1376.50
—
0
6
70
602
1.17
0.60
4.4
3.7
46.51
48.64
%
0.30
70
590
12
80
1.50
0.59
1.2
1.2
371.25
377.19
u/l
0.01
12
72
48
400
1.21
0.58
1.4
1.4
26.90
23.24
u/l
0.34
42
339
889
8639
1.06
0.58
3.3
3.2
102.72
90.18
ug/l
1.20
851
8236
0
23
0.00
0.58
0.0
1.8
—
1.21
—
0
23
13
89
1.46
0.58
1.9
1.9
1.74
4.28
nmol/l
—
7
69
8
54
1.48
0.57
1.0
1.1
—
—
—
0
0
61
523
1.17
0.55
3.1
2.2
97.13
95.19
%
0.29
61
504
43
357
1.21
0.55
1.1
1.1
17.64
15.44
au/ml
—
7
106
389
3692
1.07
0.55
2.1
2.4
318.47
321.40
umol/l
0.22
352
3317
46
385
1.20
0.55
1.2
1.3
350.28
246.59
u/ml
1.33
29
238
121
1093
1.12
0.53
1.4
1.4
—
—
—
0
0
23
179
1.29
0.51
1.4
1.5
—
—
—
0
0
30
242
1.24
0.51
3.2
2.9
7.16
7.33
mmol/l
0.16
30
234
45
380
1.19
0.50
1.8
1.5
—
—
—
0
0
28
225
1.25
0.49
1.3
1.3
—
—
—
0
0
7
45
1.56
0.49
5.4
3.0
0.65
0.61
mmol/l
—
7
45
15
110
1.37
0.48
1.1
1.6
—
—
—
0
0
20
154
1.30
0.48
2.2
1.8
—
—
—
0
0
11
76
1.45
0.48
1.8
1.4
—
—
—
0
0
39
327
1.20
0.47
1.8
1.8
—
—
—
0
0
34
408
0.83
0.47
1.6
1.5
—
—
—
0
0
110
998
1.11
0.46
3.8
3.8
75.49
79.25
ng/l
0.22
97
892
13
94
1.39
0.46
2.5
1.2
—
—
—
0
0
84
751
1.12
0.46
8.9
10.8
0.68
0.64
%
0.30
84
746
50
431
1.16
0.45
3.0
3.3
1.54
1.36
mg/l
0.71
42
395
82
733
1.12
0.45
4.8
3.4
24.27
24.32
mmol/l
0.04
82
725
37
311
1.19
0.44
3.1
2.1
121.88
130.38
g/l
1.51
32
250
10
69
1.45
0.44
2.5
2.6
54.20
48.78
umol/l
—
10
59
42
360
1.17
0.41
1.4
1.3
—
18.87
—
0
5
29
240
1.21
0.41
1.9
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
46.63
—
0
6
11
79
1.39
0.40
1.8
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
10.1
—
10.05
—
0
17
8
61
1.31
0.39
1.3
1.3
—
—
—
0
0
26
214
1.22
0.39
1.0
1.1
102.81
97.08
%
0.68
26
201
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
360
3451
1.05
0.39
1.3
1.3
25.35
25.68
iu/ml
0.02
83
1028
21
169
1.25
0.38
1.6
1.2
2.32
0.81
u/ml
0.61
14
86
9
71
1.27
0.36
1.0
1.2
40.90
49.91
u/ml
—
9
71
9
124
0.72
0.35
2.6
1.6
—
—
—
0
0
9
124
0.72
0.35
2.6
1.6
—
—
—
0
0
9
124
0.72
0.35
2.6
1.6
—
—
—
0
0
85
777
1.10
0.34
8.9
10.5
1.17
1.33
%
1.53
85
772
129
1202
1.08
0.34
3.4
4.4
5.43
25.22
ug/l
1.71
108
943
45
398
1.13
0.32
1.9
1.6
—
—
—
0
0
7
52
1.35
0.31
1.1
1.3
—
—
—
0
0
7
56
1.25
0.29
3.6
2.8
0.71
1.20
%
—
7
56
37
326
1.14
0.28
1.4
1.4
163.89
155.74
au/ml
—
9
90
11
85
1.30
0.28
1.8
1.4
—
—
—
0
0
111
1039
1.07
0.28
1.1
1.1
—
—
—
0
0
22
187
1.18
0.26
1.2
1.3
0.16
0.27
nmol/l
0.56
14
135
8
67
1.19
0.26
2.3
1.6
61.13
100.17
ng/l
—
8
67
5
71
0.70
0.26
1.0
1.1
—
—
—
0
0
34
301
1.13
0.25
1.1
1.1
—
—
—
0
0
9
73
1.23
0.25
1.2
1.3
—
—
—
0
0
84
782
1.08
0.25
2.8
3.1
201.35
148.84
ng/l
0.62
77
704
9
76
1.19
0.24
1.3
2.3
17.10
125.98
ug/l
—
9
67
31
274
1.13
0.24
2.6
2.5
19.78
111.34
ug/min
2.90
22
177
6
81
0.74
0.24
1.0
1.1
101.33
91.55
%
—
6
67
198
2064
0.95
0.24
2.0
2.1
—
—
—
0
0
27
307
0.88
0.23
1.1
1.0
2.03
2.12
eliau/ml
0.03
12
154
96
902
1.07
0.23
2.3
2.2
7.49
7.37
ug/l
0.02
77
810
42
463
0.90
0.23
1.0
1.1
4.60
5.37
u/ml
0.15
23
256
163
1558
1.05
0.23
1.5
1.4
24.52
25.46
iu/l
0.14
144
1346
21
181
1.16
0.22
1.6
1.2
—
31.83
—
0
6
24
210
1.14
0.21
1.1
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
8.14
—
0
11
75
801
0.93
0.21
1.5
1.7
0.33
0.29
mg/l
0.22
27
369
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
15
176
0.85
0.20
1.1
1.1
26.36
15.02
u/ml
—
9
78
51
471
1.09
0.20
1.2
1.1
—
—
—
0
0
6
50
1.20
0.19
1.3
1.2
72.33
72.96
ug/l
—
6
50
1416
14244
0.97
0.19
4.3
4.4
5.68
5.75
mmol/l
1.45
1314
13412
31
279
1.11
0.19
1.1
1.1
128.71
118.21
%
0.75
31
258
6
52
1.15
0.19
1.3
1.3
—
—
—
0
0
6
52
1.15
0.19
1.3
1.3
—
—
—
0
0
6
53
1.13
0.18
3.3
2.1
—
—
—
0
0
6
53
1.13
0.18
3.3
2.1
—
—
—
0
0
6
53
1.13
0.18
3.5
2.1
—
—
—
0
0
31
280
1.11
0.18
1.3
1.2
—
—
—
0
0
31
281
1.11
0.17
1.3
1.2
20.57
1891.08
iu/ml
—
7
69
18
157
1.15
0.17
1.3
1.1
—
—
—
0
0
51
475
1.08
0.17
1.2
1.1
—
—
—
0
0
71
670
1.06
0.17
3.1
2.7
1.36
1.30
%
0.16
71
665
137
1422
0.96
0.16
5.8
6.0
—
—
—
0
0
41
442
0.93
0.16
1.0
1.1
0.19
1.13
u/ml
2.15
17
190
6
76
0.79
0.15
1.3
1.2
—
—
—
0
0
36
332
1.09
0.15
1.7
1.7
6034.48
10210.06
e6/l
1.00
27
238
165
1598
1.04
0.15
4.2
4.2
32.09
31.95
%
0.06
122
1146
43
401
1.07
0.14
1.0
1.1
2.32
3.24
u/ml
0.44
30
200
17
151
1.13
0.13
1.2
1.9
—
—
—
0
0
20
180
1.11
0.13
1.5
1.5
—
—
—
0
0
10
117
0.85
0.13
1.0
1.3
—
—
—
0
0
67
703
0.95
0.13
1.7
1.6
40.54
11.02
u/ml
0.66
12
188
49
462
1.06
0.13
1.3
1.3
—
—
—
0
0
16
179
0.89
0.12
1.4
1.5
—
—
—
0
0
16
179
0.89
0.12
1.4
1.5
—
—
—
0
0
37
346
1.07
0.12
1.1
1.0
0.05
0.27
u/ml
1.60
14
109
13
114
1.14
0.11
2.9
2.4
—
—
—
0
0
16
177
0.90
0.10
1.4
1.5
—
—
—
0
0
5
45
1.11
0.09
1.0
1.1
—
—
—
0
0
5
45
1.11
0.09
1.0
1.1
—
—
—
0
0
36
381
0.94
0.09
1.2
1.2
—
—
—
0
0
13
145
0.90
0.09
1.1
1.1
—
—
—
0
0
455
4601
0.98
0.09
4.0
3.5
7.65
7.79
mmol/l
0.26
384
4009
639
6337
1.01
0.09
1.8
1.9
1.35
1.36
mmol/l
0.02
537
5546
46
481
0.96
0.08
1.7
1.4
0.59
0.46
nmol/l
0.30
34
387
8
76
1.05
0.07
6.6
1.5
24.38
28.93
umol/l
—
8
68
8
78
1.03
0.07
1.1
1.4
155.00
152.43
pmol/l
—
8
78
24
226
1.06
0.06
1.2
1.4
—
0.44
nmol/l
—
0
12
13
142
0.91
0.06
2.4
1.8
—
—
—
0
0
11
121
0.91
0.06
3.1
3.8
—
—
—
0
0
17
182
0.93
0.05
4.2
5.3
15.48
87.61
u/ml
—
5
58
114
1120
1.02
0.05
2.2
2.5
77.61
74.02
ml/min/173m2
0.36
48
460
30
287
1.05
0.05
4.4
3.7
32.99
24.27
mg/l
0.60
20
200
49
505
0.97
0.05
1.1
1.1
0.92
4.93
eliau/ml
—
6
79
13
120
1.08
0.05
1.2
1.1
1.09
1.05
ratio
0.77
13
101
46
446
1.03
0.04
1.0
1.1
3.95
1.64
u/ml
0.43
24
218
38
367
1.04
0.04
1.1
1.1
7.70
4.88
u/ml
0.23
20
158
408
4054
1.01
0.04
4.7
4.2
9.43
8.64
mg/mmol
0.12
247
2546
19
200
0.95
0.03
1.3
1.5
—
—
—
0
0
1382
13840
0.99
0.03
5.3
5.4
37.72
38.02
mmol/mol
0.65
1302
13218
319
3171
1.01
0.03
1.3
1.3
5.71
10.13
u/ml
1.12
119
1325
25
241
1.04
0.02
1.5
1.4
—
—
—
0
0
89
901
0.99
0.02
1.5
1.5
—
—
—
0
0
21
218
0.96
0.02
1.1
1.3
—
—
—
0
0
10
93
1.08
0.02
1.6
1.8
—
—
—
0
0
29
298
0.97
0.02
1.1
1.1
3.70
2.57
—
6
54
14
134
1.05
0.00
2.1
2.4
52.13
30.56
mg/l
—
8
100
145
1443
1.01
0.00
2.9
3.0
0.72
0.75
ug/l
0.15
85
830
14
135
1.04
0.00
1.1
1.3
—
—
—
0
0
14
135
1.04
0.00
1.1
1.3
—
—
—
0
0
18
185
0.97
0.00
1.3
1.5
—
—
—
0
0
18
185
0.97
0.00
1.3
1.5
—
—
—
0
0
52
519
1.00
0.00
1.1
1.1
2.11
2.80
u/ml
0.32
33
280
11
106
1.04
0.00
1.1
1.3
6.85
6.29
mmol/l
0.20
11
97
191
1908
1.00
0.00
4.6
4.0
23.63
21.61
%
0.87
83
801
45
452
1.00
0.00
4.0
3.5
48.32
1229.92
u/ml
2.10
39
388
14
142
0.99
0.00
1.4
1.7
—
—
—
0
0
18
183
0.98
0.00
1.3
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
3.75
—
0
8
9
92
0.98
-0.00
2.1
1.8
—
—
—
0
0
7
71
0.99
-0.00
3.0
1.9
—
—
—
0
0
7
71
0.99
-0.00
3.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
7.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
1.54
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
0.07
—
0
9
7
71
0.99
-0.00
3.0
1.9
—
—
—
0
0
7
71
0.99
-0.00
3.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_OPTNEURITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_OPTNEURITIS | 1.515 [1.3, 1.76] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.525 |
During the follow-up period (1.1.1998 — 31.12.2019), 352 out of 4881 females with H7_OPTNEURITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_OPTNEURITIS | 1.457 [1.25, 1.69] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 331 out of 2288 males with H7_OPTNEURITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_OPTNEURITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.204% | 0.266% |
| 5 | 0.939% | 1.733% |
| 10 | 2.566% | 4.544% |
| 15 | 4.917% | 8.48% |
| 20 | 8.402% | 13.804% |
Relationships between endpoints
↥Index endpoint: H7_OPTNEURITIS – Optic neuritis
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data