optic papillitis: Swelling of the optic disk, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause optic atrophy and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1005 |
4. Check minimum number of eventsNone |
1005 |
5. Include endpointsNone |
1005 |
6. Filter based on genotype QC (FinnGen only) |
893 |
Control definitions (FinnGen only)
- Control exclude
- H7_OPTNERVE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H47
- Name in latin
- Oedema papillae non specificatum
Similar endpoints
↥List of similar endpoints to
Papilloedema, unspecified
based on the number of shared cases.
Similar with more cases:
- Other disorders of optic [2nd] nerve and visual pathways
- Disorders of optic nerve and visual pathways
- Diseases of the eye and adnexa
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5484 | 3197 | 2258 |
| Only index persons | 4991 | 2970 | 2021 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.09 | 0.06 |
| Only index persons | 0.10 | 0.11 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 42.25 | 38.70 | 47.19 |
| Only index persons | 41.63 | 37.90 | 47.11 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 893 | 568 | 325 |
| Unadjusted period prevalence (%) | 0.18 | 0.20 | 0.15 |
| Median age at first event (years) | 47.50 | 41.60 | 57.81 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 930
- Matched controls
- 9300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01EC01
ATC
acetazolamide; systemic
34.5
314.4
208
77
H47.1
ICD-10 Finland
Papilloedema, unspecified
4503599627370496.0
307.7
898
*
XCK00
NOMESCO Finland
Perimetry
16.0
248.5
236
193
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
13.5
232.0
247
242
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
10.3
218.6
295
400
G93.2
ICD-10 Finland
Benign intracranial hypertension
871.3
217.1
205
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
17.0
182.7
161
113
TAB00
NOMESCO Finland
Lumbar puncture
12.1
178.4
198
203
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
16.2
162.2
146
106
Z01.0
ICD-10 Finland
Examination of eyes and vision
6.1
159.4
402
1026
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
+∞
148.0
138
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
18.7
135.1
111
67
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.9
128.9
235
432
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.4
116.1
231
460
XCK10
NOMESCO Finland
Photography of fundus of eye
6.6
111.9
210
394
H47.3
ICD-10 Finland
Other disorders of optic disc
1080.0
101.1
97
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
46.6
96.4
57
13
CS494
NOMESCO Finland
Other visual field testing
12.5
84.7
86
75
H46
ICD-10 Finland
Optic neuritis
+∞
83.6
79
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
11.2
69.1
75
72
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
11.6
67.7
72
67
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
21.5
64.9
49
24
H47.2
ICD-10 Finland
Optic atrophy
+∞
63.3
60
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.2
58.1
183
518
H53.4
ICD-10 Finland
Visual field defects
10.3
56.0
64
66
H53.1
ICD-10 Finland
Subjective visual disturbances
4.8
53.7
135
320
R51.80
ICD-10 Finland
Headache
3.0
43.6
256
1059
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.1
42.0
58
76
AA1AD
NOMESCO Finland
CT of head and brain
2.7
41.5
322
1535
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
15.1
39.2
35
24
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
9.4
36.2
44
49
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
8.8
30.7
39
46
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
38.5
29.5
37
10
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
11.4
29.5
31
28
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
11.4
28.6
30
27
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
11.0
27.9
30
28
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
26.9
116
395
37791
ICD-8 Finland
Other diseases of retina and optic nerve, Papilloedema. Stasis papillae
+∞
24.1
23
*
L04AA06
ATC
mycophenolic acid; systemic
6.1
23.2
41
70
N03AX11
ATC
topiramate; oral
4.8
22.9
53
116
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
22.5
229
1187
H02AB06
ATC
prednisolone; systemic
2.0
22.3
461
3098
Z3229
NOMESCO Finland
Other healthcare associate professional
3.0
21.1
100
359
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
21.1
440
2950
L04AX01
ATC
azathioprine; systemic
3.9
20.3
62
168
H34.8
ICD-10 Finland
Other retinal vascular occlusions
5.8
20.0
37
66
A02BC02
ATC
pantoprazole; systemic
1.9
19.7
622
4736
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.5
19.1
68
205
PAW37
NOMESCO Finland
Biopsy of temporal artery
39.3
18.6
23
6
127
Kela drug reimbursment
Transplant complication
6.0
18.0
32
55
E66.8
ICD-10 Finland
Other obesity
3.1
18.0
81
282
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.7
17.9
58
164
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
14.0
17.8
30
22
XCD20
NOMESCO Finland
Photoangiography of eye
7.2
17.4
26
37
L04AD02
ATC
tacrolimus; systemic
7.2
17.4
26
37
XCH00
NOMESCO Finland
Eye pressure measurement
3.6
17.4
58
167
N03AX14
ATC
levetiracetam; systemic
4.7
17.4
41
91
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.6
17.2
33
61
C03CA01
ATC
furosemide; systemic
2.0
16.8
238
1381
H02AB09
ATC
hydrocortisone; systemic
4.7
16.7
39
86
E66.01
ICD-10 Finland
Obesity due to excess calories
2.4
16.5
127
580
Z94.0
ICD-10 Finland
Kidney transplant status
7.2
16.2
24
34
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
48.4
16.1
19
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
13.9
16.1
27
20
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
21.4
16.0
23
11
B03XA02
ATC
darbepoetin alfa; parenteral
5.6
15.3
29
53
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
15.3
147
736
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
23.8
15.2
21
9
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
3.5
15.1
54
163
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.4
14.3
52
159
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
19.5
14.3
21
11
Z3231
NOMESCO Finland
Registered nurse
1.8
14.1
262
1646
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
14.1
72
269
ZXA10
NOMESCO Finland
Bilateral
2.0
14.0
172
944
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
54.2
13.8
16
*
N18.8
ICD-10 Finland
Other chronic renal failure
5.2
13.7
28
55
G47.3
ICD-10 Finland
Sleep apnoea
1.9
13.5
211
1253
H53.2
ICD-10 Finland
Diplopia
3.6
13.3
44
126
G44.2
ICD-10 Finland
Tension-type headache
2.0
13.3
157
847
TK800
NOMESCO Finland
Hemodialysis
5.0
13.2
28
57
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
12.8
213
1288
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
10.7
12.8
24
23
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
12.5
147
791
XCW12
NOMESCO Finland
Assessment of colour vision
131.7
12.5
13
*
C08CA01
ATC
amlodipine; oral
1.7
12.2
295
1986
H43.1
ICD-10 Finland
Vitreous haemorrhage
4.3
12.1
31
74
N02AX02
ATC
tramadol; systemic, rectal
1.7
12.0
364
2599
N02BE01
ATC
paracetamol; systemic, rectal
2.1
11.8
818
7251
ZX120
NOMESCO Finland
Intravenous
2.3
11.8
94
435
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.7
11.7
63
242
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.3
11.6
23
44
JN4AD
NOMESCO Finland
Body CT examination
2.2
11.5
102
493
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
11.4
115
585
J01FF01
ATC
clindamycin; systemic
1.7
11.2
245
1599
E23.06
ICD-10 Finland
Empty sella
43.9
10.9
13
*
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
43.9
10.9
13
*
A02BC01
ATC
omeprazole; systemic
1.7
10.9
245
1611
PA2AD
NOMESCO Finland
CT angiography of brain
9.7
10.8
21
22
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
9.7
10.8
21
22
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
11.4
10.6
19
17
A10AB05
ATC
insulin aspart; parenteral
2.3
10.4
81
370
AAF10
NOMESCO Finland
Lumboperitoneal shunt
+∞
10.4
10
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.5
10.4
20
37
H52.0
ICD-10 Finland
Hypermetropia
4.0
10.4
29
74
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.2
10.3
21
41
G03.9
ICD-10 Finland
Meningitis, unspecified
19.0
10.3
15
8
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
10.2
353
2577
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
10.2
354
2589
F05
ICPC
Visual disturbance other
3.0
10.0
45
157
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
40.5
10.0
12
*
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
40.5
10.0
12
*
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
7.7
9.9
22
29
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
9.9
453
3520
R42
ICD-10 Finland
Dizziness and giddiness
1.7
9.9
199
1265
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
9.8
261
1785
G35
ICD-10 Finland
Multiple sclerosis
5.0
9.8
21
43
H02AB02
ATC
dexamethasone; systemic
2.1
9.7
100
511
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
15.2
9.5
15
10
H57.1
ICD-10 Finland
Ocular pain
2.7
9.5
51
196
R4190
NOMESCO Finland
Nutritional therapy
2.7
9.5
52
202
CKC12
NOMESCO Finland
Photocoagulation of retina
2.9
9.5
45
162
PH4YT
NOMESCO Finland
Dilatation of vein of head or brain
101.0
9.4
10
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
17.7
9.4
14
8
3770A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Papilloedema
+∞
9.4
9
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
12.5
9.4
16
13
WX704
NOMESCO Finland
Intubation
2.2
9.2
78
370
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
9.1
136
790
WX872
NOMESCO Finland
Intensive care
2.7
9.1
48
183
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
9.1
677
5821
CS2P4
NOMESCO Finland
Optic nerve head imaging
8.1
8.9
19
24
H02AB04
ATC
methylprednisolone; systemic
1.9
8.9
125
713
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
4.7
8.9
20
43
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.8
8.8
26
69
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.4
8.8
61
265
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
8.8
364
2747
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
7.7
8.7
19
25
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
8.6
111
616
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
20.2
8.5
12
6
XA800
NOMESCO Finland
Neuropsychological investigation
2.6
8.4
47
184
WX882
NOMESCO Finland
High dependency care
3.4
8.4
30
91
H36.01
ICD-10 Finland
Diabetic maculopathy
4.5
8.4
20
45
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
8.4
115
650
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
4.7
8.4
19
41
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
8.4
96
511
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
8.3
113
637
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
8.3
61
273
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.1
8.2
33
108
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
8.2
8.1
17
21
SPAT1153
SPAT
Removal of sutures
1.6
7.9
250
1768
ZXC95
NOMESCO Finland
Use of surgical navigator
4.7
7.9
18
39
XCW10
NOMESCO Finland
Assessment of vision
4.7
7.9
18
39
L01AX03
ATC
temozolomide; systemic
13.2
7.9
13
10
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
7.9
85
443
G91.0
ICD-10 Finland
Communicating hydrocephalus
10.9
7.8
14
13
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.4
7.7
27
81
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
7.7
288
2114
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
7.7
215
1478
WX402
NOMESCO Finland
General anaesthesia
1.6
7.7
203
1377
D33.30
ICD-10 Finland
Acoustic neuroma
8.9
7.6
15
17
ZXD05
NOMESCO Finland
Urgent procedure
1.5
7.5
266
1926
SFA30
NOMESCO Finland
Three-surface restoration
1.5
7.5
360
2779
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.6
7.5
24
68
A10AE04
ATC
insulin glargine; parenteral
2.0
7.4
87
466
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.7
7.4
16
21
SPAT1263
SPAT
Sampling
1.5
7.4
373
2907
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
7.3
189
1273
N03AF02
ATC
oxcarbazepine; oral
2.8
7.3
37
138
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
11.0
7.3
13
12
JL9AE
NOMESCO Finland
Ultrasound examination of pancreas transplant
+∞
7.3
7
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
9.5
7.3
14
15
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.4
7.3
25
74
C07AB07
ATC
bisoprolol; oral
1.5
7.3
355
2745
WX725
NOMESCO Finland
Noninvasive ventilation
2.3
7.2
54
243
R01AD09
ATC
mometasone; nasal
1.5
7.2
412
3281
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.2
228
1610
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
4.0
7.2
20
51
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
7.2
190
1288
J01AA02
ATC
doxycycline; systemic
1.5
7.1
647
5625
AAF15
NOMESCO Finland
Ventriculoatrial shunt
20.2
7.1
10
5
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
8.0
7.1
15
19
B05DA
ATC
Isotonic solutions
8.0
7.1
15
19
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.8
7.1
21
56
R50.9
ICD-10 Finland
Fever, unspecified
1.7
7.1
145
921
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
8.9
7.1
14
16
B01AB05
ATC
enoxaparin; parenteral
1.5
7.1
243
1747
J01MA12
ATC
levofloxacin; systemic
1.7
7.0
143
906
SPAT1260
SPAT
Consultation of another employee
1.7
7.0
153
987
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.2
7.0
18
43
137
Kela drug reimbursment
Uraemia requiring dialysis
7.1
7.0
16
23
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
7.0
67
334
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
7.0
72
369
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.9
336
2588
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
6.9
202
1400
V03AE02
ATC
sevelamer; oral
13.9
6.9
11
8
H26.4
ICD-10 Finland
After-cataract
2.0
6.9
69
350
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.8
6.8
20
53
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
6.8
6.8
16
24
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
6.8
184
1251
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.2
6.8
17
28
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.5
6.8
41
168
G91.8
ICD-10 Finland
Other hydrocephalus
40.4
6.8
8
*
E66.9
ICD-10 Finland
Obesity, unspecified
2.4
6.7
44
187
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.9
6.7
89
498
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
22.7
6.7
9
*
N06AA09
ATC
amitriptyline; systemic
2.0
6.6
74
390
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.2
6.6
55
259
N03AX16
ATC
[U] pregabalin
1.6
6.6
180
1225
H02AB07
ATC
prednisone; oral
1.8
6.6
108
643
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.0
6.6
29
100
E23.00
ICD-10 Finland
Panhypopituitarism
12.3
6.6
11
9
B05DB
ATC
Hypertonic solutions
8.8
6.6
13
15
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
10.1
6.5
12
12
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
3.2
6.5
25
80
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.8
6.5
17
30
R01AD08
ATC
fluticasone; nasal
1.5
6.4
245
1794
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
70.3
6.4
7
*
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
14.4
6.4
10
7
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.7
6.4
34
131
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.4
276
2075
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
8.2
6.3
13
16
XX3DW
NOMESCO Finland
Time consuming IT work
1.9
6.3
86
485
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
2.7
6.3
32
120
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.3
6.3
47
212
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
9.3
6.3
12
13
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
6.3
94
546
M31.6
ICD-10 Finland
Other giant cell arteritis
18.2
6.3
9
5
G97.1
ICD-10 Finland
Other reaction to spinal and lumbar puncture
18.2
6.3
9
5
T82
ICPC
Obesity
2.3
6.3
46
206
SPAT1262
SPAT
Handing over of treatment supplies
1.7
6.3
133
852
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
26.9
6.2
8
*
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.9
6.1
28
99
M03BX02
ATC
tizanidine; oral
1.4
6.1
518
4384
H52.1
ICD-10 Finland
Myopia
2.3
6.1
45
202
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
6.1
103
620
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.6
6.1
19
53
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
6.0
122
771
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
6.0
45
203
V03AE01
ATC
polystyrene sulfonate; oral
5.2
6.0
17
33
KH1AD
NOMESCO Finland
CT of urinary organs
2.5
6.0
35
141
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.5
6.0
35
141
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
237
214
14.52
234.55
1.4
1.4
457.58
464.57
mg/l
0.04
229
205
219
195
14.38
217.96
1.4
1.3
3.64
3.69
mmol/l
0.22
205
186
202
195
12.96
189.96
1.6
1.4
276.19
671.36
e6/l
0.31
161
154
196
194
12.53
180.97
1.5
1.3
21.40
15.07
e6/l
0.22
150
147
110
71
17.44
129.42
1.2
1.1
53.25
40.16
mg/l
0.38
89
58
108
68
17.84
128.66
1.2
1.0
341.57
229.27
mg/l
0.58
90
60
97
54
19.94
122.47
1.3
1.0
1.14
1.08
u/l
0.24
41
25
98
66
16.48
112.52
1.2
1.0
—
—
—
0
0
90
55
18.01
108.51
1.4
1.2
0.61
0.54
ratio
0.58
47
32
107
92
13.01
106.69
1.1
1.1
—
—
—
0
0
98
81
13.41
100.00
1.1
1.1
—
—
—
0
0
164
331
5.80
79.70
2.8
2.2
39.14
38.96
u/l
0.04
148
303
202
519
4.69
73.83
1.5
1.3
118.72
36.33
au/ml
—
5
41
211
569
4.50
72.41
2.8
2.4
19.76
17.13
au/ml
0.22
18
60
66
5
141.89
62.74
1.2
1.0
—
—
—
0
0
100
203
5.40
47.53
2.5
2.3
11.17
11.83
mg/l
0.34
94
191
193
681
3.31
43.25
3.0
2.6
9.65
10.51
g/l
2.73
173
629
60
83
7.66
41.53
1.4
1.2
—
—
—
0
0
535
3319
2.44
38.30
7.5
5.0
35.92
36.34
g/l
1.01
510
3123
260
1158
2.73
37.90
2.7
2.2
29.63
29.42
s
0.12
251
1133
669
4619
2.60
37.48
7.8
5.2
6.65
6.51
mmol/l
0.86
644
4300
38
36
10.96
35.07
2.3
2.7
582.37
686.36
u/ml
0.32
38
36
570
3764
2.33
33.59
12.0
7.3
1.21
1.21
mmol/l
1.05
503
3268
397
2266
2.31
32.99
2.5
2.1
248.48
254.42
u/l
0.02
380
2153
518
3309
2.28
32.73
12.3
12.0
1.18
1.20
inr
0.35
435
2753
202
854
2.74
32.06
2.7
2.1
389.16
387.21
nmol/l
0.04
196
800
34
34
10.34
30.19
1.5
1.4
—
—
—
0
0
508
3372
2.12
27.28
11.3
7.0
1.20
1.21
mmol/l
2.59
477
3124
173
756
2.58
25.24
6.6
4.4
0.60
1.77
mmol/l
3.18
134
646
31
35
9.13
25.18
1.1
1.0
—
—
—
0
0
32
15
22.04
22.24
1.2
1.1
—
—
—
0
0
628
4710
2.03
21.92
13.1
9.3
4.43
4.04
e9/l
3.30
561
4092
202
1026
2.24
20.72
10.9
6.3
1.05
1.06
mmol/l
0.18
192
960
416
2755
1.92
20.52
3.6
3.6
42.21
70.48
ng/l
0.44
281
1768
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
32
49
6.73
20.12
1.2
1.1
—
—
—
0
0
32
50
6.59
19.75
1.2
1.1
—
—
—
0
0
28
13
22.16
19.58
1.2
1.0
14.60
5.83
mg/g
0.62
28
13
25
30
8.54
19.33
1.1
1.3
—
—
—
0
0
129
553
2.55
19.32
1.6
2.8
65.43
66.90
g/l
1.25
121
516
376
2449
1.90
19.16
4.9
2.6
56.67
61.28
u/l
0.65
353
2282
102
395
2.78
18.68
10.2
12.5
16.62
15.75
%
1.95
97
380
727
5896
2.07
18.47
6.1
4.2
12.58
10.77
mm/h
3.03
697
5529
727
5918
2.05
17.96
13.0
7.8
80.11
77.94
u/l
0.41
707
5612
49
123
4.15
17.83
2.3
2.6
22.76
25.63
iu/ml
—
5
10
227
1276
2.03
17.59
5.4
3.7
0.83
0.82
mmol/l
0.49
221
1210
159
786
2.23
17.18
9.8
9.5
0.28
0.79
mmol/l
0.69
116
656
148
718
2.26
16.71
10.2
10.0
96.98
95.66
%
2.84
140
697
160
803
2.20
16.63
9.8
9.4
13.48
12.49
kpa
1.90
152
778
160
803
2.20
16.63
9.8
9.4
4.95
5.10
kpa
1.23
152
774
541
4062
1.79
16.49
9.5
6.4
10.99
11.81
umol/l
0.50
520
3867
139
667
2.27
16.08
16.0
7.5
9.42
8.85
mmol/l
0.42
134
642
31
60
5.31
15.41
2.6
2.4
458.04
605.87
e6/l
0.72
24
46
31
60
5.31
15.41
2.7
2.6
197.04
225.37
e6/l
0.30
24
49
493
3662
1.74
15.04
3.5
2.5
72.83
74.39
nmol/l
0.64
464
3352
304
1983
1.79
14.52
7.1
4.1
94.43
91.78
%
1.08
297
1939
97
415
2.49
14.48
6.3
8.0
22.93
24.50
mmol/l
2.57
91
397
119
559
2.29
14.42
5.2
4.3
104.89
82.19
ng/l
0.79
100
503
213
1247
1.92
14.36
2.2
1.9
—
—
—
0
0
379
2641
1.73
14.34
3.8
3.2
2.35
2.35
mmol/l
0.38
352
2420
118
556
2.29
14.19
5.2
4.8
4.97
5.09
kpa
0.83
112
537
79
309
2.70
14.15
4.0
6.1
1.57
1.53
%
0.16
74
288
105
478
2.35
13.66
5.1
5.1
0.60
1.47
mmol/l
1.29
65
345
155
827
2.05
13.58
4.9
4.4
244.90
249.57
u/l
0.10
147
796
50
155
3.35
13.44
1.1
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
57
194
3.06
13.15
5.3
4.5
0.38
0.35
iu/ml
0.19
27
102
192
1121
1.90
12.92
3.8
2.5
22.72
23.24
%
0.20
183
1051
562
4435
1.68
12.79
5.4
3.7
9.99
4.84
estimate
0.21
136
937
22
37
6.07
12.63
1.2
1.2
—
—
—
0
0
335
2327
1.69
12.38
6.1
4.3
18.37
9.49
mg/mmol
1.34
236
1491
288
1924
1.72
12.28
3.7
2.8
348.29
333.99
umol/l
1.56
263
1717
214
1318
1.81
12.07
3.8
2.5
12.44
13.55
umol/l
1.55
203
1229
68
268
2.66
12.00
2.0
1.5
1.02
0.03
iu/ml
0.53
11
42
868
7874
2.54
11.90
28.2
16.3
139.63
139.60
mmol/l
0.20
860
7709
52
179
3.02
11.78
10.0
6.8
1288.60
345.82
iu/ml
—
10
22
868
7882
2.52
11.73
28.4
16.4
3.94
3.95
mmol/l
0.26
859
7698
202
1234
1.81
11.67
3.8
2.4
2.29
2.36
g/l
0.98
191
1147
294
2000
1.69
11.61
3.6
3.3
1468.44
1121.89
ng/l
0.81
247
1665
560
4481
1.63
11.48
5.5
3.7
0.00
0.34
estimate
0.50
132
879
316
2209
1.65
11.15
2.8
2.2
3.06
2.78
mg/l
1.35
288
1927
279
1894
1.68
11.00
2.1
1.8
1.89
1.14
mg/l
0.57
219
1438
548
4398
1.60
10.79
5.4
3.7
0.00
0.00
estimate
0.50
130
925
364
2654
1.61
10.75
5.4
3.4
7.49
7.95
mmol/l
1.14
323
2282
351
2543
1.61
10.60
5.9
3.2
31.59
83.00
e6/l
1.18
276
1915
111
577
2.05
10.34
7.3
3.6
1.21
1.23
mmol/l
1.52
100
492
143
812
1.90
10.33
7.6
6.3
—
—
—
0
0
24
53
4.62
10.29
2.0
3.3
879.08
1401.72
mg
0.75
24
53
19
19
10.18
10.04
1.1
1.2
—
—
—
0
0
19
19
10.18
10.04
1.1
1.1
—
—
—
0
0
254
1724
1.65
9.86
4.9
2.6
5.06
6.95
e6/l
1.35
233
1561
24
55
4.45
9.84
3.2
2.6
—
—
—
0
0
639
5397
1.59
9.46
6.4
4.4
1104.67
1670.68
e6/l
—
9
77
69
308
2.34
9.38
3.2
2.8
97.70
92.32
%
1.21
69
298
305
2192
1.58
9.26
5.2
3.1
0.30
0.38
e6/l
0.36
240
1578
102
535
2.02
9.26
1.9
1.6
—
—
—
0
0
865
7967
2.23
9.16
25.1
14.2
20.54
22.55
mg/l
1.13
773
6486
21
30
7.14
9.06
1.0
1.0
—
—
—
0
0
51
201
2.63
9.03
1.4
1.2
—
—
—
0
0
41
144
2.93
9.01
1.2
1.1
52.25
67.83
iu/ml
—
8
30
327
2403
1.56
8.95
5.8
3.7
0.00
0.01
estimate
1.15
118
872
155
942
1.77
8.94
2.1
1.8
—
—
—
0
0
149
896
1.79
8.91
2.1
1.9
—
—
—
0
0
41
147
2.87
8.69
1.5
1.5
—
—
—
0
0
17
19
9.09
8.55
1.2
1.3
—
—
—
0
0
17
19
9.09
8.55
1.2
1.1
—
—
—
0
0
17
19
9.09
8.55
1.2
1.2
—
—
—
0
0
21
50
4.27
8.23
1.1
1.1
1301.43
1471.76
miu/ml
0.28
21
50
16
18
9.02
8.06
1.1
1.3
—
—
—
0
0
481
3898
1.48
7.99
3.7
2.8
—
—
estimate
—
0
0
71
347
2.13
7.78
2.2
1.4
10.11
8.95
u/l
0.33
62
277
32
109
3.00
7.45
1.4
1.5
22.92
26.64
ng/l
0.41
32
109
121
723
1.77
7.35
1.3
1.3
136.50
141.27
u/ml
0.05
47
285
116
686
1.79
7.30
12.7
8.8
1.36
1.32
mmol/l
0.17
116
679
45
187
2.48
7.19
2.1
1.6
—
—
—
0
0
51
227
2.32
7.02
2.0
1.7
—
—
—
0
0
104
605
1.81
6.91
2.9
2.3
5002.60
6386.72
u/l
0.23
31
257
59
282
2.17
6.86
2.9
2.7
192.42
180.09
%
0.43
59
270
722
6446
1.54
6.81
5.4
4.4
14.78
14.61
pmol/l
1.16
683
5953
50
224
2.30
6.79
2.4
2.9
—
—
—
0
0
72
376
1.99
6.63
2.6
2.0
11.21
6.38
iu/ml
0.64
17
88
784
7145
1.62
6.61
7.9
5.8
39.94
38.42
mmol/mol
3.62
756
6754
54
253
2.20
6.60
1.8
2.0
905.12
456.56
ug/l
0.35
49
233
13
15
8.77
6.56
1.2
1.3
—
—
—
0
0
54
254
2.20
6.54
1.7
1.8
—
—
—
0
0
28
96
2.98
6.47
1.8
2.0
—
—
—
0
0
37
148
2.56
6.42
1.5
1.3
4.70
5.79
u/ml
0.16
23
66
807
7420
1.66
6.42
6.0
4.6
6.01
5.82
mmol/l
3.08
754
6881
37
149
2.54
6.34
1.4
1.3
2.11
4.46
u/ml
0.79
18
56
178
1223
1.56
6.28
3.1
2.5
105.98
112.17
ug/g
0.17
154
969
54
259
2.15
6.24
1.2
1.1
3.01
4.38
—
8
37
44
196
2.31
6.08
2.2
1.5
131.41
149.28
au/ml
0.35
14
53
215
1550
1.50
6.06
1.8
1.7
37989243.35
28831991.69
pmol/l
0.09
179
1318
40
171
2.40
6.06
9.9
2.0
1.11
0.88
nmol/l
0.98
35
142
196
1389
1.52
5.99
4.1
3.7
225.42
381.28
ng/l
0.90
143
989
409
3332
1.41
5.99
5.2
3.5
0.00
0.02
estimate
1.97
115
791
517
4385
1.40
5.97
4.2
3.2
126.28
98.76
ug/l
1.75
486
4143
62
322
1.99
5.82
6.2
5.8
24.28
24.59
mmol/l
0.34
56
309
77
432
1.85
5.76
1.7
1.6
—
—
—
0
0
82
471
1.81
5.69
1.5
1.6
282.19
303.70
mu/l
0.35
77
432
879
8329
2.01
5.69
30.8
17.6
78.69
73.97
umol/l
2.83
873
8237
42
189
2.28
5.68
1.4
3.5
13.82
2.49
ratio
0.43
22
106
876
8294
1.97
5.64
18.3
11.1
26.99
25.73
u/l
0.97
859
8078
166
1149
1.54
5.63
2.0
1.7
1251.82
1146.79
nmol/l
1.00
137
882
46
216
2.19
5.63
1.9
1.7
—
—
—
0
0
34
140
2.48
5.59
1.1
1.1
—
—
—
0
0
54
271
2.05
5.58
2.0
2.0
—
—
—
0
0
45
211
2.19
5.53
1.5
3.7
129.50
75.47
mg/l
0.23
34
180
45
211
2.19
5.53
1.4
3.8
26.53
51.13
mg/l
1.10
35
179
191
1372
1.49
5.43
4.2
2.8
1.29
0.85
e6/l
0.75
100
708
59
310
1.96
5.38
2.5
2.2
1.41
1.41
g/l
0.00
51
283
37
162
2.34
5.34
1.8
1.4
10.03
19.44
u/l
2.38
30
138
10
11
9.17
5.29
1.1
1.4
—
—
—
0
0
88
529
1.73
5.24
2.1
2.5
3.49
6.97
ug/l
3.97
82
473
53
274
1.99
5.07
1.5
1.9
1.49
2.54
ug/l
0.40
44
248
89
543
1.71
5.04
2.6
3.7
4.54
4.58
pmol/l
0.14
83
488
27
106
2.59
4.92
2.0
1.7
—
—
—
0
0
804
7500
1.53
4.72
6.6
5.3
1.87
1.87
mu/l
0.01
771
7025
196
1454
1.44
4.68
2.8
2.7
2.44
2.44
mmol/l
0.01
183
1302
177
1288
1.46
4.68
4.5
3.0
2.83
2.71
e6/l
0.07
86
629
345
2821
1.35
4.61
4.7
3.3
30.71
30.84
u/l
0.02
322
2675
18
59
3.09
4.53
1.1
1.2
—
—
—
0
0
38
183
2.12
4.42
1.6
1.6
—
—
—
0
0
260
2045
1.38
4.41
3.4
2.2
—
—
—
0
0
8
9
8.95
4.28
1.1
1.6
—
—
—
0
0
17
56
3.07
4.25
1.6
1.7
—
—
—
0
0
22
84
2.66
4.25
1.4
1.2
0.20
0.17
nmol/l
0.86
16
61
25
102
2.49
4.24
1.1
1.1
98.80
97.00
%
0.14
25
93
108
725
1.55
4.19
3.3
2.5
0.21
0.22
g/l
0.23
103
677
32
147
2.22
4.19
8.6
2.8
10.82
8.33
pmol/l
0.73
32
147
90
582
1.60
4.10
3.0
2.6
67.40
72.37
ml/min/173m2
0.43
35
241
797
7468
1.47
4.09
22.9
13.2
84.75
86.99
ml/min/173m2
1.84
753
6781
32
149
2.19
4.06
1.7
1.5
—
—
—
0
0
248
1959
1.36
4.05
5.0
3.7
1.02
1.02
kg/l
0.94
172
1294
397
3361
1.32
4.04
2.4
2.0
99.83
96.47
pmol/l
0.69
247
1811
9
14
6.48
3.99
1.0
1.1
—
—
—
0
0
112
767
1.52
3.98
4.1
3.1
—
—
—
0
0
809
7612
1.48
3.97
5.5
4.6
1.36
1.46
mmol/l
12.22
768
7152
43
227
1.94
3.93
1.6
1.4
188.03
233.97
u/ml
0.93
34
128
41
213
1.97
3.92
1.2
1.2
—
—
—
0
0
818
7719
1.50
3.90
6.2
5.2
2.67
2.72
mmol/l
0.87
777
7268
8
11
7.33
3.86
2.9
1.6
—
—
—
0
0
8
11
7.33
3.86
1.1
1.1
—
—
—
0
0
8
11
7.33
3.86
1.3
1.4
—
—
—
0
0
275
2223
1.34
3.83
2.0
1.6
18.66
20.13
nmol/l
1.01
238
1905
97
649
1.55
3.83
1.4
1.3
197.06
247.82
u/ml
0.34
90
603
39
201
1.98
3.82
1.1
1.2
—
1.27
—
0
11
68
417
1.68
3.82
1.5
1.4
—
—
—
0
0
7
8
8.80
3.77
1.3
1.0
—
—
—
0
0
7
8
8.80
3.77
1.3
1.0
—
—
—
0
0
35
175
2.04
3.73
1.3
1.7
—
—
—
0
0
25
109
2.33
3.71
1.3
1.3
—
—
—
0
0
250
2003
1.34
3.68
1.6
1.5
2.08
2.25
g/l
1.06
170
1252
50
286
1.79
3.59
1.4
1.3
—
—
—
0
0
809
7643
1.45
3.57
5.6
4.7
4.50
4.62
mmol/l
3.07
770
7217
7
9
7.83
3.56
1.0
1.2
—
—
—
0
0
277
2281
1.31
3.32
1.4
1.4
2.47
1.89
u/ml
0.25
84
647
29
142
2.08
3.29
2.3
1.9
—
—
—
0
0
6
7
8.62
3.26
1.2
1.4
—
—
—
0
0
13
43
3.05
3.26
1.5
4.3
86.83
131.04
umol/l
—
6
27
378
3251
1.27
3.20
2.0
1.9
1.43
1.34
mmol/l
1.31
322
2794
24
112
2.17
3.08
2.1
1.6
—
—
—
0
0
6
8
7.54
3.06
6.5
5.8
6.55
7.86
mmol/l
—
6
8
20
88
2.30
2.95
1.6
2.1
—
—
—
0
0
14
52
2.72
2.89
3.4
3.9
10.78
11.59
index
—
9
41
40
230
1.77
2.87
1.3
1.2
—
—
—
0
0
24
116
2.10
2.85
4.5
4.0
1.25
1.32
%
0.05
24
107
610
5598
1.26
2.83
4.6
3.3
45.74
42.62
u/l
0.42
595
5328
123
918
1.39
2.82
5.5
3.0
5.19
8.38
umol/l
3.50
106
790
90
636
1.46
2.78
2.4
2.4
9.63
12.38
nmol/l
2.39
84
582
5
6
8.37
2.75
1.2
1.2
—
—
—
0
0
6
10
6.03
2.70
1.2
1.3
—
—
—
0
0
37
213
1.77
2.67
1.6
1.5
0.31
0.41
nmol/l
0.52
32
175
12
43
2.81
2.65
1.2
1.8
—
—
—
0
0
12
43
2.81
2.65
1.2
1.8
—
—
—
0
0
39
229
1.73
2.63
1.3
1.2
—
—
—
0
0
12
41
2.95
2.62
1.9
1.7
—
—
—
0
0
10
30
3.36
2.60
2.5
4.0
8.40
9.00
mg/l
—
10
30
21
101
2.10
2.54
1.0
1.0
—
—
—
0
0
732
6906
1.28
2.48
29.6
17.5
13.79
13.47
%
8.47
725
6832
23
116
2.01
2.47
1.1
1.7
—
—
—
0
0
23
116
2.01
2.47
1.1
1.2
—
19.67
—
0
6
24
124
1.96
2.42
1.3
1.2
—
—
—
0
0
72
1006
0.69
2.37
1.7
1.8
3.46
3.45
ratio
0.03
55
757
8
22
3.66
2.36
1.4
1.4
—
—
—
0
0
11
39
2.84
2.34
1.1
1.3
—
—
—
0
0
11
39
2.84
2.34
1.1
1.3
—
—
—
0
0
102
762
1.38
2.34
5.7
2.4
33.95
34.28
u/l
0.04
86
629
761
7231
1.29
2.32
4.8
3.9
1.41
1.25
mmol/l
4.29
718
6749
77
549
1.44
2.31
1.8
1.4
18.10
20.90
iu/l
0.38
66
463
65
449
1.48
2.29
2.4
3.3
103.98
169.75
ng/l
1.96
57
410
32
186
1.75
2.27
1.2
1.1
34.88
16.43
au/ml
—
5
58
11
41
2.70
2.21
1.0
1.6
—
—
—
0
0
193
1594
1.27
2.19
1.4
1.3
14.73
29.99
iu/ml
3.46
42
466
28
159
1.78
2.15
1.3
1.6
—
—
—
0
0
89
662
1.38
2.12
4.8
4.6
107.67
30.95
ug/l
0.34
71
540
892
8711
1.59
2.10
36.6
21.9
261.43
254.63
e9/l
2.51
876
8557
892
8712
1.58
2.08
36.4
21.8
90.31
90.51
fl
0.71
884
8636
892
8714
1.58
2.05
37.8
22.3
40.12
40.33
%
0.60
883
8632
892
8714
1.58
2.05
36.5
21.8
4.49
4.51
e12/l
0.29
877
8542
892
8718
1.57
2.00
36.9
22.0
133.77
135.08
g/l
1.82
884
8638
42
273
1.56
1.98
1.2
1.2
—
15.62
—
0
11
16
77
2.10
1.97
1.1
1.1
—
95.14
—
0
7
12
51
2.37
1.95
1.2
1.2
—
—
—
0
0
23
127
1.83
1.95
4.7
4.3
71.17
299.29
u/ml
0.63
23
120
15
72
2.10
1.87
1.4
1.1
117.47
111.90
pmol/l
0.14
15
72
28
168
1.69
1.82
3.1
2.4
342.43
111.62
ug/min
0.53
20
95
55
765
0.70
1.80
1.5
1.6
3.48
3.41
mmol/l
0.18
38
528
285
2504
1.20
1.77
4.9
3.1
0.00
0.05
estimate
0.81
113
774
35
228
1.56
1.67
1.6
1.4
268.58
305.77
ug/g
0.43
19
132
10
43
2.34
1.59
1.2
1.6
—
—
—
0
0
25
152
1.66
1.58
2.4
1.4
—
—
—
0
0
31
464
0.66
1.52
1.3
1.5
1.12
1.18
ratio
0.09
19
293
222
1939
1.19
1.46
5.9
5.3
8.36
2.33
ug/l
0.67
200
1751
7
28
2.51
1.45
5.4
2.9
0.64
0.62
mmol/l
—
7
28
9
39
2.32
1.43
1.0
1.6
—
—
—
0
0
31
454
0.67
1.38
1.3
1.5
—
—
—
0
0
37
256
1.46
1.38
1.1
1.3
—
—
—
0
0
74
576
1.31
1.37
1.5
1.4
—
—
—
0
0
9
41
2.21
1.37
3.4
3.9
0.78
0.78
index
—
9
41
32
464
0.68
1.36
1.3
1.5
1.01
1.22
ratio
0.94
20
293
32
464
0.68
1.36
1.3
1.5
1.08
0.93
ratio
0.52
20
293
68
869
0.77
1.33
1.5
1.6
781.17
1004.43
mu/l
2.21
60
745
8
34
2.36
1.29
1.0
1.2
—
—
—
0
0
8
34
2.36
1.29
1.0
1.2
—
—
—
0
0
10
48
2.10
1.28
2.9
1.2
—
—
—
0
0
28
186
1.52
1.27
3.3
3.0
2.82
2.25
index
0.14
17
104
145
1691
0.83
1.26
2.4
2.4
—
—
—
0
0
9
45
2.01
1.23
1.1
1.1
—
—
—
0
0
16
93
1.73
1.21
1.7
2.2
33.88
33.05
pg
0.84
16
93
0
35
0.00
1.15
0.0
1.3
—
—
—
0
0
94
1122
0.82
1.05
1.8
1.8
1.40
1.44
%
0.22
85
1003
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
7
35
2.01
1.00
1.4
1.0
124.14
121.00
%
—
7
35
17
110
1.56
0.91
1.5
1.3
—
—
—
0
0
42
537
0.77
0.88
1.1
1.0
—
—
—
0
0
17
111
1.54
0.88
1.2
1.4
—
—
—
0
0
174
1556
1.15
0.86
5.3
4.5
22.01
21.24
%
0.27
93
729
34
256
1.34
0.86
2.0
2.1
2.30
5.04
iu/l
2.47
12
106
12
72
1.68
0.85
1.1
1.2
—
—
—
0
0
17
112
1.53
0.85
1.2
1.4
—
—
—
0
0
604
5811
1.11
0.83
3.4
3.5
—
—
—
0
0
23
163
1.42
0.82
2.2
3.9
28.84
25.82
mg/l
0.13
16
119
17
113
1.51
0.82
1.2
1.4
—
—
—
0
0
17
247
0.68
0.80
1.4
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
—
—
0
0
12
74
1.63
0.78
1.1
1.2
—
—
—
0
0
24
175
1.38
0.75
1.1
1.1
10.71
6.72
u/ml
0.30
13
92
12
75
1.61
0.75
1.1
1.2
—
—
—
0
0
12
75
1.61
0.75
1.1
1.2
—
—
—
0
0
61
507
1.22
0.74
1.4
1.4
—
—
—
0
0
22
159
1.39
0.73
1.1
1.1
18.89
8.92
u/ml
0.48
12
71
101
884
1.16
0.70
5.5
4.5
30.32
31.48
%
0.58
78
605
10
61
1.65
0.68
4.2
2.0
3.60
2.42
u/field
—
5
36
9
59
1.53
0.68
1.2
1.3
65.56
72.86
umol/l
—
9
59
42
340
1.25
0.66
1.1
1.2
0.90
0.88
g/l
0.21
42
340
141
1561
0.89
0.65
2.2
2.2
—
—
—
0
0
11
70
1.58
0.65
2.8
2.5
—
—
—
0
0
6
104
0.57
0.62
1.7
2.2
—
—
—
0
0
5
30
1.67
0.61
3.4
2.1
—
—
—
0
0
5
30
1.67
0.61
3.4
2.1
—
—
—
0
0
12
80
1.51
0.60
1.1
1.2
—
—
—
0
0
12
80
1.51
0.60
2.1
1.7
—
—
—
0
0
6
35
1.72
0.57
1.0
1.1
—
—
—
0
0
13
90
1.45
0.55
1.1
1.2
—
—
—
0
0
6
38
1.58
0.54
3.8
2.2
—
—
—
0
0
9
61
1.48
0.53
2.0
1.5
0.99
1.24
promille
—
9
47
35
286
1.23
0.53
1.7
1.8
38.71
41.99
nmol/l
0.48
35
274
12
83
1.45
0.52
1.1
1.4
—
—
—
0
0
6
40
1.50
0.51
3.2
1.9
—
—
—
0
0
6
40
1.50
0.51
3.2
1.9
—
—
—
0
0
6
40
1.50
0.51
3.2
1.9
—
—
—
0
0
6
40
1.50
0.51
3.2
1.9
—
—
—
0
0
26
207
1.26
0.50
2.6
2.4
5.19
6.25
umol/l
0.31
20
157
40
336
1.20
0.48
1.5
1.4
—
—
—
0
0
11
76
1.45
0.48
2.4
1.7
—
—
—
0
0
11
76
1.45
0.48
2.4
1.7
—
—
—
0
0
11
76
1.45
0.48
2.4
1.7
—
—
—
0
0
28
342
0.81
0.46
1.7
1.7
—
—
—
0
0
39
330
1.19
0.44
1.1
1.1
1.50
1.56
g/l
0.68
39
330
5
31
1.62
0.43
3.4
2.1
—
—
—
0
0
12
162
0.74
0.42
1.3
1.3
—
—
—
0
0
32
267
1.21
0.42
3.3
3.5
76.88
5368.64
u/ml
0.83
25
235
6
94
0.64
0.42
1.5
1.2
—
—
—
0
0
8
59
1.36
0.41
1.1
1.6
0.61
0.47
e9/l
—
8
59
37
315
1.18
0.40
1.1
1.1
0.55
0.66
ratio
—
5
35
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
8
61
1.31
0.39
1.3
1.6
—
—
—
0
0
14
106
1.33
0.39
1.2
1.4
—
—
—
0
0
14
106
1.33
0.39
1.2
1.4
—
—
—
0
0
30
355
0.84
0.38
2.0
1.7
—
—
—
0
0
25
206
1.22
0.38
1.1
1.1
3.54
1.65
u/ml
0.46
12
114
14
107
1.31
0.37
1.2
1.4
—
—
—
0
0
49
555
0.88
0.37
1.4
1.5
—
—
—
0
0
18
144
1.25
0.35
1.3
1.3
—
—
—
0
0
18
144
1.25
0.35
1.3
1.3
—
—
—
0
0
6
43
1.40
0.35
3.8
8.0
—
45.42
—
0
12
22
182
1.21
0.33
1.1
1.3
—
—
—
0
0
6
46
1.31
0.33
8.3
3.2
0.92
1.22
%
—
6
46
48
426
1.13
0.33
1.4
1.3
70.00
241.85
miu/ml
6.76
16
213
6
47
1.28
0.32
1.0
1.4
158.58
174.90
pmol/l
—
6
47
22
183
1.21
0.32
1.2
1.5
8189.12
13756.47
e6/l
0.49
17
134
10
75
1.34
0.30
1.1
1.0
—
—
—
0
0
48
432
1.12
0.28
1.5
1.6
0.34
0.32
mg/l
0.06
19
189
28
244
1.15
0.26
1.2
1.2
4.01
3.09
u/ml
0.20
14
137
22
188
1.17
0.25
1.1
1.3
—
—
—
0
0
5
39
1.28
0.23
3.0
8.0
14.22
417.15
ug/l
—
5
28
157
1503
1.05
0.22
1.3
1.3
2.85
11.27
u/ml
3.39
53
583
31
346
0.89
0.21
1.5
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.0
1.3
401.80
535.05
u/l
—
5
37
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
167
1606
1.05
0.20
1.4
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
121
1155
1.05
0.19
3.5
3.1
0.84
0.77
ug/l
0.41
80
734
41
375
1.10
0.19
1.9
1.7
7.95
3.60
mg/l
0.56
34
279
10
121
0.82
0.18
1.3
1.5
6.26
7.10
mmol/l
—
10
105
18
157
1.15
0.17
1.4
1.8
—
—
—
0
0
5
66
0.76
0.17
1.6
1.6
—
—
—
0
0
8
70
1.14
0.16
5.0
3.8
—
—
—
0
0
14
158
0.88
0.12
1.0
1.0
4.32
2.82
eliau/ml
—
6
69
17
154
1.11
0.10
1.1
1.1
0.51
0.25
u/ml
—
6
53
18
197
0.91
0.10
1.5
1.6
—
—
—
0
0
94
913
1.03
0.09
1.8
2.0
—
—
—
0
0
204
2075
0.98
0.08
2.0
1.7
—
—
—
0
0
6
57
1.05
0.08
1.8
1.4
—
—
—
0
0
38
397
0.96
0.07
1.5
1.7
—
—
—
0
0
9
88
1.02
0.07
1.1
1.2
—
—
—
0
0
22
210
1.05
0.03
1.6
1.4
148.64
136.42
pmol/l
0.04
22
204
35
339
1.03
0.03
1.5
1.7
25.98
9.67
u/ml
—
9
72
33
334
0.99
0.00
1.6
1.5
—
—
—
0
0
10
101
0.99
0.00
1.2
1.6
—
—
—
0
0
30
305
0.98
0.00
1.4
1.6
62.29
55.78
ug/l
0.33
30
305
0
5
0.00
-0.00
0.0
1.2
—
12.40
—
0
5
109
1090
1.00
-0.00
2.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.4
—
71.37
—
0
9
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
5.81
—
0
7
6
66
0.91
-0.00
4.3
1.8
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.4
—
52.86
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint H7_PAPILLOEDEMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PAPILLOEDEMA | 1.805 [1.5, 2.18] | < 0.001 |
| Birth year | 1.0 [0.99, 1.01] | 0.933 |
During the follow-up period (1.1.1998 — 31.12.2019), 302 out of 2534 females with H7_PAPILLOEDEMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PAPILLOEDEMA | 1.735 [1.45, 2.08] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.026 |
During the follow-up period (1.1.1998 — 31.12.2019), 318 out of 1743 males with H7_PAPILLOEDEMA died.
Mortality risk
Mortality risk for people of age
years, who have H7_PAPILLOEDEMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.222% | 0.329% |
| 5 | 1.191% | 2.395% |
| 10 | 2.856% | 5.595% |
| 15 | 5.566% | 10.492% |
| 20 | 10.02% | 17.3% |
Relationships between endpoints
↥Index endpoint: H7_PAPILLOEDEMA – Papilloedema, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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