epiglottitis: Inflammation of the epiglottis.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
676 |
4. Check minimum number of eventsNone |
676 |
5. Include endpointsNone |
676 |
6. Filter based on genotype QC (FinnGen only) |
598 |
Control definitions (FinnGen only)
- Control exclude
- J10_UPPERINFEC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J05
- Name in latin
- Epiglottitis acuta
Similar endpoints
↥List of similar endpoints to
Acute epiglottitis
based on the number of shared cases.
Similar with more cases:
- Acute upper respiratory infections
- Diseases of the respiratory system
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5000 | 2010 | 2955 |
| Only index persons | 4606 | 1904 | 2702 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.06 | 0.08 |
| Only index persons | 0.09 | 0.07 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 41.89 | 40.32 | 42.82 |
| Only index persons | 41.03 | 39.96 | 41.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 598 | 286 | 312 |
| Unadjusted period prevalence (%) | 0.12 | 0.10 | 0.14 |
| Median age at first event (years) | 46.12 | 40.02 | 51.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 621
- Matched controls
- 6210
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J05.1
ICD-10 Finland
Acute epiglottitis
+∞
307.7
520
*
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
19.8
114.0
92
54
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
9.8
83.9
106
128
UDH02
NOMESCO Finland
Rhinopharyngoscopy
8.1
76.9
115
170
J36
ICD-10 Finland
Peritonsillar abscess
11.5
69.0
75
73
4643A
ICD-9 Finland
Acute laryngitis and tracheitis, Acute epiglottitis
+∞
64.7
61
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
7.1
59.8
99
162
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
22.4
51.0
38
18
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
16.4
49.9
43
28
46404
ICD-8 Finland
Acute laryngitis and tracheitis, Epiglottidis acuta
+∞
46.4
44
*
J04.0
ICD-10 Finland
Acute laryngitis
9.1
44.9
57
68
J05.0
ICD-10 Finland
Acute obstructive laryngitis [croup]
+∞
33.6
32
*
R21
ICPC
Throat symptom/complaint
3.0
32.3
191
802
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
+∞
30.5
29
*
R07.0
ICD-10 Finland
Pain in throat
4.4
30.3
82
206
EMB10
NOMESCO Finland
Tonsillectomy
4.9
28.5
66
146
J03.0
ICD-10 Finland
Streptococcal tonsillitis
6.9
26.3
42
65
J01FF01
ATC
clindamycin; systemic
2.6
25.3
207
1009
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
24.8
312
1845
H02AB06
ATC
prednisolone; systemic
2.3
23.7
322
1957
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
21.3
305
1870
J01DB01
ATC
cefalexin; oral
3.2
20.8
547
4340
GBB00
NOMESCO Finland
Tracheostomy
16.0
19.9
32
21
TDM10
NOMESCO Finland
Puncture of maxillary antrum
7.8
19.2
27
36
ENA32
NOMESCO Finland
Incision of deep pharyngeal infection
54.2
18.1
21
*
J39.0
ICD-10 Finland
Retropharyngeal and parapharyngeal abscess
43.3
17.4
21
5
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
17.0
242
1448
J46
ICD-10 Finland
Status asthmaticus
6.9
16.7
26
39
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
15.8
163
856
WX707
NOMESCO Finland
Fiberoscopic intubation
58.1
14.8
17
*
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
14.8
289
1911
4659X
ICD-9 Finland
Acute upper respiratory infections of multiple or unspecified sites, Unspecified site
+∞
14.6
14
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
14.2
326
2265
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
13.8
170
951
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
13.8
126
627
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
13.6
336
2378
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
13.6
112
532
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
+∞
13.6
13
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
13.4
138
720
R06.0
ICD-10 Finland
Dyspnoea
2.1
13.1
167
944
M79.6
ICD-10 Finland
Pain in limb
1.9
13.0
277
1862
J01DA01
ATC
[U] cefalexin
1.9
13.0
384
2865
N02AX02
ATC
tramadol; systemic, rectal
1.9
12.4
270
1820
ZXE00
NOMESCO Finland
One hour or less
1.9
12.3
243
1588
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.0
12.1
55
194
A02BC02
ATC
pantoprazole; systemic
1.9
12.0
411
3174
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.4
11.6
29
68
ZXD05
NOMESCO Finland
Urgent procedure
1.9
11.6
198
1231
UJC01
NOMESCO Finland
Scopy of lower throat
9.5
11.1
22
24
J01AA02
ATC
doxycycline; systemic
1.9
10.5
461
3760
J38.4
ICD-10 Finland
Oedema of larynx
16.4
10.4
16
10
P01AB01
ATC
metronidazole; oral, rectal
1.8
10.3
244
1665
N02BE01
ATC
paracetamol; systemic, rectal
2.3
10.2
547
4751
J01FA09
ATC
clarithromycin; systemic
1.8
10.0
186
1178
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
9.9
73
329
R03AC02
ATC
salbutamol; inhalant
1.7
9.8
330
2472
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.3
9.7
25
60
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
9.5
185
1185
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
9.5
97
501
J01FA15
ATC
telithromycin; oral
2.4
9.4
65
284
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
+∞
9.4
9
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
9.7
9.3
18
19
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.6
9.2
30
86
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
9.1
131
762
ZXA10
NOMESCO Finland
Bilateral
2.0
8.9
104
564
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.9
8.7
42
153
J39.1
ICD-10 Finland
Other abscess of pharynx
50.7
8.7
10
*
A02BC05
ATC
esomeprazole; systemic
1.7
8.4
233
1638
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.0
8.4
18
23
R13
ICD-10 Finland
Dysphagia
2.6
8.4
49
198
SPAT1263
SPAT
Sampling
1.7
8.3
233
1643
J01
ICD-10 Finland
Acute sinusitis
3.0
8.1
36
125
R50.9
ICD-10 Finland
Fever, unspecified
2.0
8.1
92
492
L28
ICPC
Limited function/disability (L)
2.0
8.1
97
529
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
8.1
213
1474
R03AK07
ATC
formoterol and budesonide; inhalant
1.8
8.1
133
806
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.7
7.9
18
39
J37.0
ICD-10 Finland
Chronic laryngitis
3.6
7.9
26
75
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.4
7.9
57
255
R52.9
ICD-10 Finland
Pain, unspecified
2.2
7.8
69
335
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
7.8
418
3440
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
7.8
66
315
N03AX16
ATC
[U] pregabalin
1.8
7.8
126
759
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
7.7
171
1128
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
7.6
122
732
M54.5
ICD-10 Finland
Low back pain
1.6
7.6
221
1564
J02
ICD-10 Finland
Acute pharyngitis
3.0
7.5
33
114
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.5
199
1374
SPAT1310
SPAT
Counselling related to known health issue
1.7
7.5
179
1203
R05
ICPC
Cough
1.8
7.5
140
880
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
7.5
248
1812
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
7.5
59
274
UDC00
NOMESCO Finland
Ear microscopy
2.5
7.5
47
197
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
7.8
7.4
16
21
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
7.4
102
583
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
7.4
138
866
J01.4
ICD-10 Finland
Acute pansinusitis
+∞
7.3
7
*
4630A
ICD-9 Finland
Acute tonsillitis[TONSILLITIS ACUTA]
+∞
7.3
7
*
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
3.6
7.2
23
65
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.3
7.2
27
85
WX730
NOMESCO Finland
Conventional respirator
6.1
7.1
18
30
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.2
7.1
28
91
K11.2
ICD-10 Finland
Sialoadenitis
3.6
7.1
23
66
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
7.0
109
647
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
7.0
81
436
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
6.9
153
1005
N06AX11
ATC
mirtazapine; oral
1.6
6.9
196
1375
J01DA06
ATC
[U] cefuroxime
1.9
6.9
88
491
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
6.9
80
432
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
6.8
209
1492
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
6.8
56
265
ENA10
NOMESCO Finland
Biopsy of pharynx
40.5
6.8
8
*
J20
ICD-10 Finland
Acute bronchitis
2.1
6.7
62
307
R06AE07
ATC
cetirizine; oral
1.6
6.6
247
1841
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
6.6
58
282
C08CA01
ATC
amlodipine; oral
1.6
6.6
196
1387
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
6.6
52
242
L04AX01
ATC
azathioprine; systemic
3.1
6.5
26
85
J01FA10
ATC
azithromycin; systemic
1.5
6.5
329
2622
R01AD58
ATC
fluticasone, combinations; nasal
1.7
6.5
146
962
J01MA14
ATC
moxifloxacin; systemic
2.3
6.5
51
237
R20.2
ICD-10 Finland
Paraesthesia of skin
2.3
6.4
46
205
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.4
211
1528
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.8
6.4
31
114
SPAT1360
SPAT
Extensive global examination
2.6
6.3
37
150
4640A
ICD-9 Finland
Acute laryngitis and tracheitis, Acute laryngitis
+∞
6.3
6
*
46309
ICD-8 Finland
Acute tonsillitis, Unspecified
+∞
6.3
6
*
R03BA02
ATC
budesonide; inhalant
1.8
6.2
102
614
X58
ICD-10 Finland
Exposure to other specified factors
1.8
6.2
98
583
N03AX12
ATC
[U] gabapentin; oral
1.9
6.2
88
507
J03
ICD-10 Finland
Acute tonsillitis
3.6
6.2
20
57
AA1AD
NOMESCO Finland
CT of head and brain
1.6
6.2
149
998
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
6.1
135
884
Z00.0
ICD-10 Finland
General medical examination
1.7
6.1
113
705
N06AX16
ATC
venlafaxine; oral
1.8
6.1
88
510
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
6.1
69
369
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
6.1
58
291
L50.9
ICD-10 Finland
Urticaria, unspecified
2.9
6.1
28
100
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.4
6.0
21
63
R02
ICPC
Shortness of breath/dyspnoea
1.9
6.0
73
399
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
6.0
55
271
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
6.1
6.0
15
25
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
6.0
59
299
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
168
695
2.94
28.79
2.2
1.8
—
—
—
0
0
132
510
3.02
25.29
1.8
1.7
—
—
—
0
0
125
487
2.96
23.47
1.8
1.7
—
—
—
0
0
344
2295
2.12
18.47
16.3
10.3
0.00
0.00
e9/l
0.11
283
1881
45
108
4.41
17.48
1.8
1.4
—
—
—
0
0
33
65
5.31
16.16
1.9
1.4
—
—
—
0
0
187
1031
2.16
16.10
1.9
1.5
—
—
—
0
0
400
2932
2.02
15.38
11.4
9.6
4.30
4.08
e9/l
0.84
350
2557
81
313
2.83
15.14
1.6
1.7
—
—
—
0
0
40
104
4.04
13.99
1.5
1.3
—
—
—
0
0
42
114
3.88
13.85
1.8
1.4
—
—
—
0
0
35
83
4.41
13.80
1.5
1.3
—
—
—
0
0
80
327
2.66
13.38
6.3
3.7
1.22
1.22
mmol/l
0.16
73
282
35
88
4.16
12.80
1.5
1.3
—
—
—
0
0
352
2578
1.84
12.35
7.0
7.0
10.03
11.85
umol/l
4.83
340
2487
383
2926
1.81
11.22
7.1
4.9
6.88
6.66
mmol/l
1.02
367
2760
295
2122
1.74
10.33
6.4
5.4
35.47
36.21
g/l
1.41
278
2005
23
49
4.84
10.31
1.6
1.2
—
—
—
0
0
169
1036
1.87
10.12
3.3
2.6
4.58
5.85
e6/l
0.62
161
946
61
253
2.56
9.87
1.4
1.3
—
—
—
0
0
207
1359
1.78
9.87
4.4
2.9
0.26
0.45
e6/l
1.04
159
972
61
255
2.54
9.71
1.8
1.6
—
—
—
0
0
301
2203
1.71
9.71
14.9
11.4
1.24
1.21
inr
0.49
249
1806
138
805
1.92
9.57
4.1
3.6
0.80
0.83
mmol/l
1.66
130
769
230
1573
1.73
9.42
4.3
3.1
49.50
60.76
e6/l
0.13
181
1187
27
71
3.93
9.32
1.6
1.3
—
—
—
0
0
105
563
2.04
9.25
9.4
8.2
12.06
12.37
kpa
0.22
105
548
104
559
2.03
9.10
9.3
8.3
1.18
0.84
mmol/l
0.38
90
465
36
117
3.20
9.09
2.1
1.6
—
—
—
0
0
192
1264
1.75
8.91
2.6
2.0
2.91
2.76
mg/l
0.32
159
1086
245
1731
1.69
8.76
4.4
3.1
—
—
—
0
0
118
678
1.91
8.49
3.0
2.5
23.17
24.36
%
0.40
107
643
280
2071
1.64
8.25
9.4
6.4
1.20
1.21
mmol/l
1.55
263
1924
310
2353
1.63
8.22
10.4
7.3
1.20
1.21
mmol/l
1.44
261
2059
32
104
3.19
8.09
5.2
7.3
155.80
220.50
iu/ml
—
5
14
421
3461
1.67
8.03
3.6
3.2
—
—
—
0
0
92
495
2.01
7.99
1.7
2.0
350.57
382.08
nmol/l
0.85
86
466
132
804
1.82
7.87
2.9
2.4
13.20
14.23
umol/l
0.85
121
759
197
1346
1.68
7.82
3.5
2.6
346.21
344.21
umol/l
0.11
167
1220
569
5140
2.28
7.73
23.7
13.5
30.23
23.59
mg/l
4.07
530
4106
113
668
1.85
7.39
10.6
6.8
104.37
104.41
mmol/l
0.03
113
668
192
1321
1.66
7.34
2.9
3.0
1342.49
1186.71
ng/l
0.18
164
1125
220
1571
1.62
7.23
2.9
2.7
55.69
64.31
u/l
0.73
210
1483
454
3856
1.66
7.13
10.6
8.1
77.34
77.47
u/l
0.02
442
3691
235
1721
1.59
6.88
3.7
3.4
7.99
8.16
mmol/l
0.22
202
1486
18
32
5.76
6.80
2.2
1.6
—
—
—
0
0
18
32
5.76
6.80
2.2
1.6
—
—
—
0
0
18
32
5.76
6.80
2.2
1.6
—
—
—
0
0
20
54
3.79
6.68
1.6
1.3
—
—
—
0
0
120
749
1.75
6.50
3.0
2.4
2.32
2.33
g/l
0.08
110
705
104
628
1.79
6.31
7.9
6.3
1.04
1.04
mmol/l
0.03
97
590
9
5
18.23
6.28
1.0
1.0
95.67
93.40
%
—
9
5
226
1671
1.55
6.21
3.5
3.5
2.34
2.35
mmol/l
0.62
205
1557
567
5193
2.06
6.16
25.4
15.9
3.95
3.97
mmol/l
0.82
557
5102
566
5186
2.03
6.05
25.3
15.7
139.28
139.68
mmol/l
3.50
556
5109
138
912
1.66
6.03
4.1
3.5
132.72
599.71
ng/l
2.09
92
691
439
3763
1.57
5.99
5.4
4.0
13.67
10.37
mm/h
4.31
415
3556
54
266
2.13
5.93
10.4
3.1
24.54
24.18
mmol/l
0.39
54
266
163
1128
1.60
5.91
2.1
1.7
1.93
1.22
mg/l
0.41
125
891
80
458
1.86
5.76
4.0
3.0
—
—
—
0
0
13
20
6.61
5.58
1.9
1.2
—
—
—
0
0
137
922
1.62
5.54
3.4
2.8
2.45
2.43
mmol/l
0.64
119
840
19
57
3.41
5.48
1.3
1.8
32.95
33.14
pg
0.06
19
57
77
444
1.84
5.42
5.9
3.4
1.73
1.83
mmol/l
0.09
69
373
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
29
116
2.57
5.11
3.2
2.0
0.28
0.35
iu/ml
0.44
16
52
59
318
1.95
5.10
3.3
4.2
102.16
83.41
ng/l
0.61
51
287
26
99
2.70
5.04
2.2
1.5
—
—
—
0
0
34
148
2.37
5.03
2.6
3.2
—
—
—
0
0
97
613
1.69
4.98
2.2
3.3
5.78
7.55
umol/l
0.90
84
553
11
16
6.98
4.97
2.9
1.6
—
—
—
0
0
11
16
6.98
4.97
2.9
1.6
—
—
—
0
0
11
16
6.98
4.97
2.9
1.6
—
—
—
0
0
11
16
6.98
4.97
2.9
1.6
—
—
—
0
0
12
20
6.10
4.93
1.9
1.2
—
—
—
0
0
16
38
4.29
4.85
1.1
1.1
—
—
—
0
0
191
1424
1.49
4.82
4.2
3.5
0.00
0.00
estimate
0.50
88
497
240
1872
1.46
4.82
3.2
3.6
30.09
32.64
u/l
0.78
227
1789
209
1588
1.48
4.80
4.9
4.2
10.95
9.16
mg/mmol
0.17
141
1007
13
25
5.29
4.79
1.8
2.2
—
—
—
0
0
328
2717
1.44
4.75
4.1
3.4
0.03
0.62
estimate
0.48
88
497
313
2575
1.43
4.68
3.7
2.9
139.55
120.13
ug/l
0.54
293
2424
24
92
2.67
4.61
1.7
1.5
—
—
—
0
0
117
793
1.59
4.54
4.1
2.8
1.45
1.82
e6/l
0.34
54
384
102
672
1.62
4.45
3.2
2.5
145.94
101.41
ug/g
0.53
85
546
137
967
1.53
4.44
1.5
1.3
30.62
31.16
iu/ml
0.02
39
303
324
2703
1.42
4.37
4.1
3.4
15.10
5.55
estimate
0.27
97
546
34
158
2.22
4.36
3.6
1.8
—
—
—
0
0
320
2666
1.41
4.34
4.2
3.4
0.00
0.00
estimate
-0.00
96
535
138
986
1.51
4.22
1.8
1.7
433.48
25295930.01
pmol/l
0.94
112
846
294
2425
1.40
4.17
3.5
2.7
—
—
estimate
—
0
0
12
26
4.68
4.07
2.0
1.2
—
—
—
0
0
62
366
1.77
4.06
5.1
3.3
66.37
67.29
g/l
0.42
57
345
540
4993
1.62
4.05
21.2
13.0
86.01
85.30
ml/min/173m2
0.33
505
4588
178
1351
1.45
3.99
1.7
1.6
19.11
20.31
nmol/l
0.56
159
1178
229
1820
1.41
3.98
4.4
3.4
40.07
78.21
ng/l
0.56
151
1206
43
229
1.94
3.88
3.4
1.7
5.81
6.56
iu/ml
0.11
11
58
12
28
4.35
3.83
1.9
1.2
—
—
—
0
0
33
161
2.11
3.78
1.3
1.3
—
21.97
—
0
8
271
2231
1.38
3.77
2.7
2.4
75.09
75.24
nmol/l
0.03
245
2057
598
5718
2.24
3.70
33.3
20.9
256.75
249.93
e9/l
1.45
586
5632
31
149
2.14
3.69
3.2
1.7
—
—
—
0
0
31
149
2.14
3.69
1.6
1.4
245.28
269.02
ug/g
0.29
21
83
8
12
6.74
3.68
3.7
5.8
—
—
—
0
0
442
3951
1.41
3.67
4.9
4.1
14.53
14.60
pmol/l
0.22
408
3666
598
5720
2.23
3.66
33.2
20.8
90.70
90.83
fl
0.30
593
5680
27
123
2.25
3.66
3.2
3.5
1.32
1.91
index
0.35
19
69
117
832
1.50
3.63
4.3
2.6
0.52
0.84
e6/l
1.06
56
423
598
5722
2.22
3.62
33.3
20.9
4.51
4.56
e12/l
1.72
583
5623
598
5722
2.22
3.62
34.1
21.3
40.38
40.98
%
2.16
591
5676
598
5725
2.20
3.56
33.6
21.0
134.92
137.59
g/l
4.31
591
5685
9
17
5.35
3.52
1.6
1.5
46.96
62.51
ug/l
—
9
17
17
63
2.75
3.51
1.3
1.3
—
—
—
0
0
28
133
2.16
3.45
1.3
1.2
—
58.61
—
0
15
104
731
1.51
3.41
1.9
1.6
1186.39
1152.56
nmol/l
0.13
72
571
30
148
2.08
3.36
1.9
1.3
—
—
—
0
0
50
294
1.76
3.35
3.4
2.8
126.08
131.95
g/l
0.95
50
286
18
71
2.58
3.32
1.3
1.2
—
—
—
0
0
18
71
2.58
3.32
1.3
1.2
—
—
—
0
0
14
48
2.96
3.32
2.2
1.6
—
—
—
0
0
579
5504
1.77
3.23
15.3
11.1
27.32
27.59
u/l
0.14
564
5390
16
61
2.67
3.15
1.2
1.1
—
—
—
0
0
13
44
3.00
3.15
2.3
1.6
—
—
—
0
0
250
2081
1.34
3.07
4.0
3.2
5.81
0.02
estimate
0.49
86
451
40
226
1.82
3.07
3.5
6.3
1.77
1.64
%
0.29
40
212
50
302
1.71
3.06
7.9
7.1
25.14
24.69
mmol/l
0.47
50
289
25
120
2.13
3.02
8.6
3.9
7.94
2.61
ratio
0.63
15
71
14
52
2.73
2.90
1.8
1.2
—
—
—
0
0
16
64
2.54
2.89
8.2
6.4
11.83
10.58
mg/l
0.49
16
57
44
261
1.74
2.88
3.5
3.5
1.23
1.83
mmol/l
0.57
30
193
7
13
5.43
2.87
3.1
1.6
—
—
—
0
0
7
13
5.43
2.87
3.1
1.6
—
—
—
0
0
7
13
5.43
2.87
3.1
1.6
—
—
—
0
0
6
9
6.72
2.87
1.0
1.3
—
—
—
0
0
71
477
1.55
2.87
2.5
2.5
32.33
34.63
u/l
0.23
58
412
142
1093
1.39
2.86
2.0
1.5
2.51
2.40
g/l
0.27
101
717
27
137
2.01
2.84
9.7
4.1
92.44
43.80
mg/l
0.34
21
124
27
137
2.01
2.84
9.7
4.1
67.55
94.55
mg/l
0.26
21
123
12
39
3.12
2.78
1.9
1.2
99.58
78.38
umol/l
0.75
12
39
11
34
3.27
2.73
2.3
1.4
—
—
—
0
0
15
60
2.54
2.72
2.3
1.5
—
—
—
0
0
15
60
2.54
2.72
2.3
1.5
—
—
—
0
0
157
1238
1.36
2.71
1.4
1.3
2.24
1.80
u/ml
0.13
46
369
512
4776
1.41
2.71
5.9
4.9
1.88
1.83
mu/l
0.45
477
4472
253
2140
1.31
2.69
2.2
2.0
94.65
96.72
pmol/l
0.29
126
1161
8
19
4.25
2.68
1.0
1.2
—
—
—
0
0
41
244
1.73
2.67
3.8
2.4
0.66
0.62
%
0.27
41
244
187
1523
1.33
2.59
2.6
2.1
153.21
252.20
u/l
1.22
178
1456
5
7
7.19
2.55
2.8
1.4
—
—
—
0
0
156
1241
1.34
2.53
3.6
2.3
—
—
—
0
0
15
63
2.42
2.48
1.1
1.2
—
24.00
—
0
5
105
790
1.40
2.41
1.9
1.9
1.52
1.44
%
0.55
93
703
6
12
5.04
2.40
1.2
1.8
116.33
86.58
nmol/24h
—
6
12
24
125
1.96
2.38
1.2
1.3
—
—
—
0
0
14
58
2.45
2.38
2.3
1.5
—
—
—
0
0
14
58
2.45
2.38
2.3
1.5
—
—
—
0
0
187
1543
1.30
2.33
3.5
2.8
0.59
0.07
estimate
0.42
85
418
14
59
2.40
2.30
2.3
1.5
—
—
—
0
0
14
59
2.40
2.30
2.3
1.5
—
—
—
0
0
16
72
2.25
2.29
1.1
1.0
0.05
0.13
u/ml
—
8
16
524
4945
1.38
2.25
4.3
4.1
1.38
1.30
mmol/l
1.41
485
4640
418
3823
1.29
2.25
3.9
3.4
52.26
46.57
u/l
0.69
392
3672
10
35
2.89
2.21
1.0
1.1
—
—
—
0
0
92
687
1.40
2.21
2.6
1.9
—
—
—
0
0
58
398
1.50
2.17
2.8
2.3
71.20
70.24
ml/min/173m2
0.06
30
180
27
152
1.81
2.15
5.5
2.6
2.18
1.26
g/l
0.32
22
138
62
433
1.48
2.13
2.7
2.0
—
—
—
0
0
21
109
1.96
2.13
1.2
1.1
0.88
3.41
u/ml
1.34
15
48
55
377
1.50
2.07
1.4
1.4
—
—
—
0
0
19
96
2.01
2.07
6.0
3.0
11.72
8.00
pmol/l
0.73
19
96
17
84
2.05
1.97
1.2
1.0
0.68
2.87
u/ml
1.22
12
29
99
764
1.35
1.95
2.6
2.0
—
—
—
0
0
18
92
1.99
1.92
1.2
1.0
0.09
2.39
u/ml
—
10
37
112
884
1.33
1.90
1.4
1.3
17.05
10.55
u/ml
0.36
39
354
7
22
3.21
1.88
2.0
2.4
—
—
—
0
0
7
22
3.21
1.88
2.0
2.4
—
—
—
0
0
20
107
1.90
1.88
1.6
4.1
30.87
35.81
umol/l
0.86
15
99
515
4884
1.32
1.84
7.0
5.9
40.32
38.76
mmol/mol
2.55
479
4662
5
12
4.19
1.82
63.6
7.0
7.74
5.38
kpa
—
5
12
544
5208
1.36
1.76
5.0
4.8
4.61
4.66
mmol/l
0.55
506
4942
6
18
3.36
1.75
1.0
1.1
—
—
—
0
0
29
179
1.65
1.73
2.2
1.8
90.66
91.56
%
0.07
29
174
24
141
1.73
1.70
1.6
2.7
10.12
12.04
mg/l
0.49
24
134
32
204
1.60
1.69
3.7
3.6
25.63
25.19
mmol/l
0.36
32
195
32
205
1.59
1.66
1.8
2.2
1307.11
4890.81
u/l
1.75
13
94
7
25
2.82
1.65
3.3
3.5
677.43
665.48
u/ml
—
7
25
24
143
1.71
1.63
1.3
1.3
—
—
—
0
0
5
14
3.59
1.62
1.2
1.0
—
—
—
0
0
5
14
3.59
1.62
1.0
1.1
—
—
—
0
0
8
32
2.52
1.60
1.0
1.1
—
—
—
0
0
55
399
1.42
1.59
1.3
1.2
70.39
141.31
u/ml
2.05
29
171
7
26
2.71
1.58
1.0
1.1
—
—
—
0
0
20
114
1.78
1.58
1.5
1.2
—
—
—
0
0
10
44
2.29
1.56
1.1
1.1
—
—
—
0
0
8
33
2.44
1.54
1.3
1.2
—
—
—
0
0
5
15
3.35
1.52
2.4
4.1
0.62
0.59
mmol/l
—
5
15
5
15
3.35
1.52
1.0
1.2
—
—
—
0
0
541
5197
1.32
1.52
5.0
4.7
1.41
1.43
mmol/l
0.57
501
4905
30
195
1.57
1.48
1.1
1.3
—
—
—
0
0
20
118
1.72
1.43
1.4
1.3
—
—
—
0
0
10
46
2.19
1.40
1.1
1.1
—
—
—
0
0
10
46
2.19
1.40
1.1
1.1
—
—
—
0
0
10
46
2.19
1.40
1.1
1.3
46.20
47.09
u/l
—
10
39
40
281
1.45
1.40
1.1
1.1
—
—
—
0
0
7
29
2.43
1.39
1.6
1.8
—
—
—
0
0
6
23
2.62
1.37
1.2
1.3
48.17
9.88
u/l
—
6
17
6
23
2.62
1.37
1.2
1.3
118.67
62.06
u/l
—
6
17
10
47
2.15
1.34
1.1
1.0
—
—
—
0
0
49
361
1.39
1.33
2.9
1.9
—
—
—
0
0
9
43
2.11
1.30
1.1
1.1
—
—
—
0
0
8
34
2.37
1.29
1.3
1.2
—
—
—
0
0
516
4953
1.25
1.27
5.2
4.7
6.16
5.88
mmol/l
3.08
465
4625
40
288
1.42
1.25
2.2
1.7
0.41
0.30
mg/l
0.63
24
135
18
108
1.69
1.23
1.4
1.2
319.27
276.19
u/ml
0.24
11
66
5
19
2.64
1.22
1.6
1.3
—
—
—
0
0
546
5282
1.28
1.21
5.8
5.4
2.70
2.77
mmol/l
0.93
507
4997
13
71
1.85
1.20
1.2
1.4
—
—
—
0
0
8
38
2.12
1.18
1.1
1.1
—
—
—
0
0
11
57
1.95
1.17
1.1
1.2
—
—
—
0
0
26
174
1.52
1.17
2.3
1.8
—
—
—
0
0
10
50
2.02
1.17
1.1
1.1
—
—
—
0
0
47
353
1.36
1.16
2.6
2.4
13.20
22.01
au/ml
—
6
36
8
39
2.06
1.15
3.1
3.4
—
—
—
0
0
50
380
1.34
1.15
4.3
2.2
3.59
8.69
ug/l
3.80
42
341
18
111
1.64
1.13
1.3
1.2
21.27
11.47
e6/l
0.21
11
85
8
41
1.96
1.09
1.1
1.2
—
83.75
—
0
8
7
32
2.20
1.08
2.0
4.1
1.00
0.87
index
—
7
32
24
162
1.50
1.05
3.0
2.2
3.66
3.66
g/l
0.00
24
157
18
114
1.60
1.03
1.3
1.3
984.64
747.53
e6/l
0.08
11
92
7
34
2.07
1.03
1.0
1.1
1026.00
1280.47
miu/ml
—
7
34
9
48
1.89
1.00
3.6
3.5
—
—
—
0
0
11
61
1.82
0.99
1.4
1.4
341.09
381.16
pmol/l
0.14
11
55
11
61
1.82
0.99
1.3
1.2
—
—
—
0
0
6
28
2.15
0.91
1.0
1.1
243.33
143.31
iu/ml
—
6
28
18
119
1.53
0.89
3.3
2.3
90.19
64.75
ug/min
0.19
12
68
44
344
1.30
0.87
1.5
1.4
23.54
25.20
iu/l
0.13
38
290
6
31
1.94
0.84
1.2
1.5
—
100.00
—
0
5
8
45
1.79
0.84
4.8
3.2
761.75
1009.33
mg
—
8
45
239
2204
1.14
0.83
2.0
1.9
1.68
1.39
mmol/l
2.01
198
1913
6
32
1.88
0.82
1.5
1.4
32.56
37.44
nmol/l
—
6
25
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
5
24
2.09
0.74
1.0
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
5
24
2.09
0.74
1.0
1.5
—
—
—
0
0
16
108
1.49
0.74
2.6
10.0
106.13
105.43
mmol/l
0.39
16
99
7
38
1.85
0.73
2.0
1.7
—
—
—
0
0
16
230
0.69
0.73
2.5
2.7
22.06
37.60
u/ml
0.71
16
223
9
57
1.59
0.71
1.0
1.1
—
—
—
0
0
7
42
1.67
0.68
1.1
1.1
140.43
100.05
pmol/l
—
7
42
8
49
1.64
0.62
1.0
1.1
—
—
—
0
0
5
30
1.67
0.61
1.6
3.0
92.20
96.13
%
—
5
30
13
88
1.49
0.61
1.2
1.1
—
—
—
0
0
17
122
1.40
0.60
3.2
3.0
1.74
1.58
mmol/l
0.15
17
116
8
53
1.52
0.58
1.0
1.3
—
—
—
0
0
21
275
0.76
0.58
1.0
1.1
1.48
1.50
g/l
0.18
21
275
6
35
1.72
0.58
1.3
1.5
—
—
—
0
0
6
35
1.72
0.58
1.0
1.0
—
—
—
0
0
22
281
0.77
0.52
1.0
1.2
0.95
0.91
g/l
0.23
22
281
6
40
1.50
0.51
1.3
1.6
—
—
—
0
0
130
1191
1.12
0.50
4.0
3.4
1.02
1.02
kg/l
0.34
80
793
61
532
1.16
0.49
8.8
6.2
—
—
—
0
0
12
166
0.72
0.48
1.3
1.5
—
—
—
0
0
14
102
1.38
0.47
1.2
1.5
0.25
0.33
nmol/l
—
9
81
18
139
1.30
0.44
1.6
1.1
—
—
—
0
0
5
31
1.62
0.43
1.4
1.5
0.60
1.06
u/field
—
5
21
13
96
1.36
0.42
2.2
1.8
—
—
—
0
0
67
748
0.88
0.41
1.8
2.0
3.59
3.55
ratio
0.08
50
583
42
485
0.86
0.40
4.7
5.0
5.76
29.16
ug/l
0.81
34
405
8
60
1.34
0.40
1.0
1.1
—
—
—
0
0
16
204
0.78
0.39
1.3
1.4
—
—
—
0
0
202
1917
1.08
0.38
5.0
4.9
2.02
2.17
ug/l
0.19
181
1745
9
71
1.27
0.36
1.2
1.6
1.50
2.30
ug/l
—
9
65
18
144
1.26
0.35
1.3
1.6
—
—
—
0
0
23
191
1.21
0.34
1.4
1.4
266.04
241.62
miu/ml
0.11
16
92
86
791
1.10
0.33
1.5
1.5
—
—
—
0
0
17
208
0.81
0.31
1.5
1.8
—
—
—
0
0
11
84
1.32
0.30
1.2
1.1
124.73
114.09
%
0.51
11
78
7
55
1.28
0.30
1.7
2.6
1.20
1.19
mmol/l
—
7
55
7
55
1.28
0.30
1.7
2.6
108.71
104.84
mmol/l
—
7
55
7
57
1.23
0.29
1.4
1.1
1.47
1.45
nmol/l
—
7
51
10
76
1.32
0.28
1.7
1.6
—
—
—
0
0
17
140
1.22
0.27
1.6
1.1
—
—
—
0
0
53
582
0.90
0.27
4.6
4.6
31.82
30.66
%
0.41
34
408
14
170
0.82
0.25
1.3
1.5
1.52
1.25
ratio
—
6
106
14
170
0.82
0.25
1.3
1.5
0.88
0.94
ratio
—
6
106
14
170
0.82
0.25
1.3
1.4
1.26
1.20
ratio
—
6
106
12
96
1.25
0.24
1.1
1.1
—
—
—
0
0
14
169
0.82
0.24
1.2
1.4
—
—
—
0
0
5
38
1.32
0.23
1.2
1.7
—
—
—
0
0
30
266
1.13
0.23
1.6
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
370.83
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.28
—
0
6
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
26
292
0.89
0.20
1.4
1.6
1080.99
1032.67
mu/l
0.09
21
235
12
99
1.22
0.19
1.5
1.8
—
—
—
0
0
15
175
0.85
0.19
1.7
1.6
—
—
—
0
0
7
58
1.21
0.18
2.0
4.9
—
57.28
u/ml
—
0
20
6
78
0.77
0.15
1.3
1.4
12.55
21.05
u/l
—
6
63
12
102
1.18
0.15
1.4
1.5
64.02
55.22
ug/l
0.42
12
102
54
571
0.94
0.13
1.5
1.7
3.58
3.46
mmol/l
0.28
35
405
13
118
1.10
0.07
2.0
1.7
—
—
—
0
0
20
187
1.07
0.06
2.3
1.7
23.77
7.80
u/ml
—
6
45
118
1163
1.02
0.04
2.8
2.9
0.75
0.76
ug/l
0.09
76
690
24
250
0.96
0.03
1.7
1.8
34.54
39.84
nmol/l
0.87
24
238
20
207
0.97
0.01
1.8
1.7
186.00
209.30
pmol/l
0.52
20
191
154
1546
0.99
0.00
3.8
4.1
20.89
21.75
%
0.29
70
661
15
152
0.99
0.00
2.3
1.9
5.37
3.92
iu/l
—
8
60
8
85
0.94
-0.00
1.0
1.1
—
1.83
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
15
150
1.00
-0.00
1.8
1.3
—
—
—
0
0
25
250
1.00
-0.00
1.2
1.6
287.56
283.73
mu/l
0.04
25
228
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
5.94
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_EPIGLOTTITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_EPIGLOTTITIS | 1.186 [0.94, 1.5] | 0.152 |
| Birth year | 0.993 [0.98, 1.0] | 0.127 |
During the follow-up period (1.1.1998 — 31.12.2019), 121 out of 1403 females with J10_EPIGLOTTITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_EPIGLOTTITIS | 1.459 [1.22, 1.74] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 282 out of 1993 males with J10_EPIGLOTTITIS died.
Mortality risk
Mortality risk for people of age
years, who have J10_EPIGLOTTITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.084% | 0.284% |
| 5 | 0.639% | 1.731% |
| 10 | 1.61% | 4.157% |
| 15 | 3.083% | 7.877% |
| 20 | 5.572% | 13.424% |
Relationships between endpoints
↥Index endpoint: J10_EPIGLOTTITIS – Acute epiglottitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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