Other congenital malformations of circulatory system

Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q28
  • Cause of death: ICD-10 Q28

2 out of 7 registries used, show all original rules.

1082

4. Check minimum number of events

None

1082

5. Include endpoints

None

1082

6. Filter based on genotype QC (FinnGen only)

984

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_CIRCULATO_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q2
Name in latin
Aliae malformationes congenitae systematis circulatorii

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5679 2954 2695
Only index persons 5251 2773 2478
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.10 0.10 0.09
Median age at first event (years)
Whole population 50.81 51.53 50.08
Only index persons 51.08 51.74 50.35

-FinnGen-

Key figures

All Female Male
Number of individuals 984 575 409
Unadjusted period prevalence (%) 0.20 0.20 0.19
Median age at first event (years) 54.74 52.64 57.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1015
Matched controls
10150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
80.0
322.2
173
26
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
+∞
307.7
580
*
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
+∞
307.7
410
*
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
51.7
282.8
165
38
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
8.3
189.4
303
494
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.6
157.6
157
135
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
27.4
152.6
106
43
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.9
131.3
180
240
AA1AD
NOMESCO Finland
CT of head and brain
4.6
125.7
517
1882
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
18.4
121.7
100
60
PA2AC
NOMESCO Finland
Cerebral angiography with X-ray
40.4
111.1
68
18
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
23.4
103.7
76
35
N03AF02
ATC
oxcarbazepine; oral
9.4
98.4
125
150
AAC40
NOMESCO Finland
Extirpation of intracranial arterio-venous malformation
+∞
94.3
89
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.0
94.2
241
591
Q28.8
ICD-10 Finland
Other specified congenital malformations of circulatory system
+∞
84.6
80
*
PA2JT
NOMESCO Finland
Very extensive embolisation of arterio-venous malformation of the brain
+∞
77.1
73
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.8
73.5
286
946
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
11.5
73.1
78
73
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
10.5
72.2
82
84
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
15.1
71.3
64
45
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
11.0
71.1
78
76
N03AX14
ATC
levetiracetam; systemic
8.1
66.3
93
125
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
32.0
65.9
43
14
D18.0
ICD-10 Finland
Haemangioma, any site
9.6
65.7
80
90
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.4
64.2
98
145
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
9.2
63.5
80
94
XA800
NOMESCO Finland
Neuropsychological investigation
6.0
63.1
119
219
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
16.1
60.1
52
34
PA2AD
NOMESCO Finland
CT angiography of brain
18.8
56.2
45
25
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
19.9
53.9
42
22
Q28.0
ICD-10 Finland
Arteriovenous malformation of precerebral vessels
+∞
52.6
50
*
PA2HT
NOMESCO Finland
Extensive embolisation of arterio-venous malformation of the brain
+∞
52.6
50
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.1
49.5
111
238
H93.1
ICD-10 Finland
Tinnitus
4.1
49.0
149
407
I60.8
ICD-10 Finland
Other subarachnoid haemorrhage
131.3
47.2
50
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
13.6
44.5
42
32
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
44.4
357
1728
PA2GT
NOMESCO Finland
Embolisation of arterio-venous malformation of the brain
+∞
44.1
42
*
N03AF01
ATC
carbamazepine; oral, rectal
4.7
43.1
105
241
XCK00
NOMESCO Finland
Perimetry
4.4
39.5
106
262
Q28.1
ICD-10 Finland
Other malformations of precerebral vessels
+∞
38.8
37
*
G40.10
ICD-10 Finland
Simple partial seizures
14.5
38.4
35
25
R51.80
ICD-10 Finland
Headache
2.7
37.5
250
1091
N03AX18
ATC
lacosamide; systemic
13.4
36.7
35
27
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.5
35.4
52
73
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
10.9
35.0
38
36
ZXC95
NOMESCO Finland
Use of surgical navigator
9.5
34.1
41
45
ZXD35
NOMESCO Finland
Usual procedure
5.3
32.6
68
136
H53.4
ICD-10 Finland
Visual field defects
6.3
30.9
53
88
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
9.1
30.0
37
42
Q28.9
ICD-10 Finland
Congenital malformation of circulatory system, unspecified
+∞
29.3
28
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
28.9
417
2504
I77.0
ICD-10 Finland
Arteriovenous fistula, acquired
82.6
28.9
32
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.7
28.8
182
765
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
27.7
432
2660
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
27.2
211
976
R4110
NOMESCO Finland
Physiotherapy
2.1
26.2
338
1931
Z2445
NOMESCO Finland
Psychologist
3.9
25.5
77
207
H53.2
ICD-10 Finland
Diplopia
4.4
25.5
65
154
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
9.1
24.3
30
34
XX4AW, ,
NOMESCO Finland
57.5
24.1
28
5
R4150
NOMESCO Finland
Neuropsychological rehabilitation
9.0
23.4
29
33
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
85.4
22.8
25
*
R4120
NOMESCO Finland
Occupational therapy
3.1
22.4
102
357
183
Kela drug reimbursment
Lamotrigin and topiramate
8.5
22.3
29
35
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
64.0
21.9
25
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
21.5
72
208
Z3226
NOMESCO Finland
Physiotherapist
2.2
21.3
218
1125
Z3231
NOMESCO Finland
Registered nurse
2.0
21.3
310
1826
WX882
NOMESCO Finland
High dependency care
4.8
21.0
48
104
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
21.0
118
464
R20.2
ICD-10 Finland
Paraesthesia of skin
2.9
20.6
106
397
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
58.8
20.0
23
*
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
6.6
19.7
32
50
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
16.8
19.7
31
19
K91
ICPC
Cerebrovascular disease
7.0
19.6
30
44
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
8.2
18.8
25
31
I67.8
ICD-10 Finland
Other specified cerebrovascular diseases
28.4
18.8
25
9
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
7.8
18.8
26
34
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.0
18.7
89
319
N03AB02
ATC
phenytoin; systemic
7.0
18.3
28
41
G40
ICD-10 Finland
Epilepsy
7.3
18.3
27
38
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
15.7
18.0
29
19
PA4AC
NOMESCO Finland
Vertebralis angiography with X-ray
29.4
17.5
23
8
K90
ICPC
Stroke/cerebrovascular accident
4.2
16.9
45
110
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
16.8
183
961
R51
ICD-10 Finland
Headache
2.9
16.5
82
301
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
16.3
167
857
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.7
15.8
25
38
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.6
15.7
53
154
Q27.3
ICD-10 Finland
Peripheral arteriovenous malformation
+∞
15.7
15
*
AAC30
NOMESCO Finland
Intracranial occlusion of vascular fistula
+∞
15.7
15
*
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
17.5
15.7
24
14
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.5
15.5
106
457
WX002
NOMESCO Finland
Sedation and analgesia
2.0
15.3
210
1195
AA5PD
NOMESCO Finland
CT examination of brain pefusion
12.0
15.1
27
23
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.2
15.0
60
194
N03AG01
ATC
valproic acid; systemic, rectal
2.6
14.5
86
346
G44.2
ICD-10 Finland
Tension-type headache
2.0
13.9
167
906
PA5AC
NOMESCO Finland
Angiography of arteries to the face with X-ray
141.8
13.5
14
*
R42
ICD-10 Finland
Dizziness and giddiness
1.8
13.4
240
1481
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
13.4
201
1174
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
13.4
89
379
AAF00
NOMESCO Finland
Ventriculostomy
14.0
13.3
22
16
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.3
13.2
34
81
M03BX01
ATC
baclofen; systemic
4.4
13.2
33
77
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.1
13.0
54
179
AA9CW, ,
NOMESCO Finland
28.8
13.0
17
6
N18
ICPC
Paralysis/weakness
4.5
12.9
31
70
Z2221
NOMESCO Finland
Medical doctor
1.7
12.7
284
1866
N03AX09
ATC
lamotrigine; oral
2.7
12.7
70
272
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
12.6
76
308
AAB30
NOMESCO Finland
Evacuation of spontaneous intracranial haematoma
70.8
12.6
14
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
9.1
12.3
25
28
Z71.8
ICD-10 Finland
Other specified counselling
1.6
12.0
365
2593
ZXE00
NOMESCO Finland
One hour or less
1.6
11.9
389
2810
WX402
NOMESCO Finland
General anaesthesia
1.7
11.9
248
1594
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.9
11.7
34
89
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
11.6
90
410
PA5JT
NOMESCO Finland
Embolisation of very extensive arterio-venous malformation of carotis externa area
+∞
11.5
11
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
11.2
217
1363
WX892
NOMESCO Finland
Monitored bed care
2.3
11.1
87
398
TAB00
NOMESCO Finland
Lumbar puncture
2.7
11.0
62
243
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
15.7
10.8
17
11
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
10.8
80
357
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.1
10.7
29
72
XX4BW, ,
NOMESCO Finland
21.7
10.7
15
7
R55
ICD-10 Finland
Syncope and collapse
2.1
10.6
110
564
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
10.5
310
2171
7478X
ICD-9 Finland
Other congenital anomalies of circulatory system, Other specified anomalies of circulatory system
+∞
10.4
10
*
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.2
10.4
27
65
PA2CG
NOMESCO Finland
Extensive MRI examination of vessels in the head with high intensity magnet
16.2
10.4
16
10
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.4
10.3
37
112
ZXD05
NOMESCO Finland
Urgent procedure
1.6
10.3
301
2103
ZX050
NOMESCO Finland
Stereotactic radiotherapy
8.0
10.1
22
28
N88
ICPC
Epilepsy
8.6
10.1
21
25
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
10.0
464
3593
N02BE01
ATC
paracetamol; systemic, rectal
1.9
10.0
903
8182
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
14.8
10.0
16
11
PA6AD
NOMESCO Finland
CT of neck arteries
2.7
9.8
51
192
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.4
9.7
69
303
G40.89
ICD-10 Finland
Other epilepsy
13.5
9.7
16
12
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
9.2
9.5
19
21
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
9.5
106
558
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
17.7
9.4
14
8
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.0
9.3
99
512
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
9.2
44
159
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
9.1
9.0
18
20
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
15.7
9.0
14
9
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.1
8.8
37
124
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
10.8
8.8
16
15
N03AX16
ATC
[U] pregabalin
1.6
8.8
227
1530
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.3
8.7
22
52
N05BA01
ATC
diazepam; systemic, rectal
1.8
8.7
131
762
XKD00
NOMESCO Finland
Uroflowmetry
1.8
8.7
134
785
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.7
8.6
27
75
R60.0
ICD-10 Finland
Localized oedema
1.9
8.6
123
704
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
27.8
8.5
11
*
Q82.2
ICD-10 Finland
Mastocytosis
90.8
8.4
9
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
7.9
8.4
18
23
PG1GT
NOMESCO Finland
Endovascular embolisation of arterio-venous malformation with radiological guidance not elsewhere classified
+∞
8.3
8
*
PG1JT
NOMESCO Finland
Very extensive endovascular embolisation of arterio-venous malformation not elsewhere classified
+∞
8.3
8
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
8.3
64
291
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.7
8.3
43
162
T78.4
ICD-10 Finland
Allergy, unspecified
2.5
8.3
52
216
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
14.6
8.2
13
9
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.6
8.2
18
24
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
8.0
132
787
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.1
8.0
74
363
L28
ICPC
Limited function/disability (L)
1.7
8.0
169
1081
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
8.0
168
1074
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.2
7.9
66
311
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
7.9
118
684
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.8
354
2693
R51.81
ICD-10 Finland
Facial pain NOS
3.1
7.8
32
106
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
15.2
7.7
12
8
G95.1
ICD-10 Finland
Vascular myelopathies
45.3
7.7
9
*
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
7.5
7.7
17
23
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.4
7.7
53
230
G81.9
ICD-10 Finland
Hemiplegia, unspecified
4.6
7.7
18
40
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
6.8
7.6
18
27
M79.6
ICD-10 Finland
Pain in limb
1.4
7.5
439
3500
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
4.3
7.5
19
45
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
7.4
718
6284
I62.9
ICD-10 Finland
Intracranial haemorrhage (nontraumatic), unspecified
80.7
7.4
8
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.8
7.4
119
705
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
4.1
7.4
20
50
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
7.4
140
870
R52.9
ICD-10 Finland
Pain, unspecified
1.8
7.3
109
630
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.7
7.3
23
64
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
7.3
389
3044
AAA00
NOMESCO Finland
Exploratory craniotomy
+∞
7.3
7
*
4301A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACH.POST MALFORMAT.ARTERIOVENOSAM]
+∞
7.3
7
*
Z2446
NOMESCO Finland
Social worker
2.0
7.2
74
378
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
30.2
7.2
9
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
30.2
7.2
9
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.2
7.1
59
277
I78.0
ICD-10 Finland
Hereditary haemorrhagic telangiectasia
20.2
7.1
10
5
N03AX23
ATC
brivaracetam; systemic
12.1
7.1
12
10
G82.2
ICD-10 Finland
Paraplegia, unspecified
12.1
7.1
12
10
H02.4
ICD-10 Finland
Ptosis of eyelid
2.8
7.1
35
129
WX872
NOMESCO Finland
Intensive care
2.3
7.0
52
233
RS222, ,
NOMESCO Finland
4.4
7.0
17
39
N19
ICPC
Speech disorder
4.0
6.9
19
48
M03BX02
ATC
tizanidine; oral
1.4
6.9
618
5294
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.1
6.8
61
297
PA2MT
NOMESCO Finland
Endovascular closure of very extensive brain aneurysm
16.8
6.8
10
6
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.2
6.7
26
83
N03AX12
ATC
[U] gabapentin; oral
1.6
6.7
158
1036
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
6.7
34
127
ZXA05
NOMESCO Finland
Left side
1.5
6.7
213
1498
I61.3
ICD-10 Finland
Intracerebral haemorrhage in brain stem
22.7
6.7
9
*
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
7.9
6.6
14
18
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
6.6
93
530
N99
ICPC
Neurological disease other
4.2
6.6
17
41
N06AX11
ATC
mirtazapine; oral
1.4
6.6
324
2489
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
3.9
6.6
19
50
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.4
6.5
42
177
WF099
NOMESCO Finland
Other radiotherapy
6.9
6.5
15
22
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
6.5
208
1464
ZXA00
NOMESCO Finland
Right side
1.5
6.5
236
1706
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.4
350
2734
PA7RT
NOMESCO Finland
Medical infusion to cerebral artery
70.3
6.4
7
*
PA5HT
NOMESCO Finland
Embolisation of extensive arterio-venous malformation of carotis externa area
70.3
6.4
7
*
G81.1
ICD-10 Finland
Spastic hemiplegia
70.3
6.4
7
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.4
131
829
UKC02
NOMESCO Finland
Cystoscopy
1.7
6.3
133
848
U07
ICPC
Urine symptom/complaint other
1.9
6.3
83
462
ZY010
NOMESCO Finland
Hospital outpatient
2.1
6.3
58
285
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
18.1
6.3
9
5
N03AF04
ATC
eslicarbazepine; oral
+∞
6.3
6
*
Q28
ICD-10 Finland
Other congenital malformations of circulatory system
+∞
6.3
6
*
Q27.4
ICD-10 Finland
Congenital phlebectasia
+∞
6.3
6
*
Q27.9
ICD-10 Finland
Congenital malformation of peripheral vascular system, unspecified
+∞
6.3
6
*
PC6CC
NOMESCO Finland
Spinal angiography, very extensive
+∞
6.3
6
*
PG1HT
NOMESCO Finland
Extensive endovascular embolisation of arterio-venous malformation not elsewhere classified
+∞
6.3
6
*
G992, Q288,
ICD-10 Finland
+∞
6.3
6
*
R41.3
ICD-10 Finland
Other amnesia
2.8
6.2
29
104
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
6.2
94
548
N28
ICPC
Limited function/disability (N)
3.4
6.2
21
62
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
6.2
107
648
N03AE01
ATC
clonazepam; systemic
2.1
6.1
56
274
H05.2
ICD-10 Finland
Exophthalmic conditions
12.6
6.1
10
8
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.4
6.0
40
171
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
2.3
6.0
42
184
R4130
NOMESCO Finland
Speech therapy
2.7
6.0
32
123
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
6.0
139
908

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
459
2301
2.82
55.80
6.2
4.2
93.51
91.40
%
1.16
447
2252
257
1002
3.10
48.73
9.5
9.5
0.95
0.92
mmol/l
0.04
204
844
501
2777
2.59
47.79
2.5
2.2
144.74
238.73
u/l
1.91
488
2646
256
1009
3.06
47.51
9.7
9.6
7.42
7.41
ph
0.09
155
562
256
1013
3.04
47.14
9.7
9.5
5.10
5.13
kpa
0.21
250
983
256
1013
3.04
47.14
9.6
9.5
16.68
12.43
kpa
13.45
250
986
508
2955
2.44
42.07
2.8
2.4
—
—
—
0
0
405
2229
2.36
36.77
2.6
2.4
—
—
—
0
0
602
4065
2.18
31.56
8.9
7.1
1.20
1.21
mmol/l
3.31
573
3774
645
4531
2.16
29.80
8.9
7.7
1.20
1.21
mmol/l
2.35
573
3943
590
4021
2.12
29.32
13.1
12.8
1.19
1.20
inr
0.39
483
3322
112
354
3.43
29.28
3.4
2.3
21.20
20.84
s
0.29
104
329
34
37
9.47
28.39
3.3
3.3
28.50
32.77
umol/l
0.70
24
26
719
5344
2.18
27.69
7.7
5.4
6.42
6.63
mmol/l
2.74
696
5069
605
4256
2.04
26.44
3.0
2.8
—
—
estimate
—
0
0
171
822
2.30
19.76
12.2
9.2
1.32
1.30
mmol/l
0.08
164
812
162
798
2.23
17.54
13.2
10.1
—
—
—
0
0
65
202
3.37
17.36
2.6
1.4
—
—
—
0
0
379
2530
1.79
16.92
4.1
3.3
0.37
0.43
e6/l
0.29
275
1836
44
106
4.29
16.87
2.5
1.5
—
—
—
0
0
261
1559
1.91
16.61
4.0
3.6
0.82
0.82
mmol/l
0.11
247
1485
67
222
3.16
16.13
2.6
1.4
554.69
645.93
e6/l
0.06
52
169
66
220
3.14
15.73
2.5
1.3
63.41
27.46
e6/l
0.38
46
161
418
2940
1.72
15.10
4.1
3.4
29.73
74.65
e6/l
1.21
313
2232
463
3397
1.67
13.95
4.9
4.0
100.82
90.09
e6/l
0.12
324
2356
268
1697
1.79
13.80
3.5
2.9
526.04
533.13
mosm/kgh2o
0.21
233
1493
382
2683
1.68
13.49
4.1
4.3
7.40
7.40
ph
0.67
271
1902
252
1594
1.77
12.92
3.4
3.0
1.54
1.01
e6/l
1.16
133
844
350
2439
1.66
12.53
5.4
4.3
—
—
—
0
0
40
117
3.52
11.76
1.1
1.2
—
—
—
0
0
230
1475
1.72
11.04
3.6
3.1
2.52
2.45
e6/l
0.04
109
731
589
4749
1.57
10.99
7.6
6.6
0.57
0.58
e9/l
0.42
501
4115
588
4761
1.56
10.59
7.6
6.6
0.04
0.04
e9/l
0.56
498
4130
968
8990
2.66
10.38
25.2
17.8
139.58
139.67
mmol/l
0.49
954
8832
469
3627
1.54
10.29
2.4
2.1
—
—
—
0
0
154
896
1.85
10.23
2.2
2.5
32.43
44.03
u/l
1.18
131
752
594
4843
1.55
10.20
7.8
6.6
1.86
1.93
e9/l
0.72
505
4305
956
8838
2.41
10.19
21.4
15.4
24.35
23.50
mg/l
0.34
840
7213
599
4914
1.53
9.83
8.1
6.9
0.19
0.19
e9/l
0.47
511
4325
358
2629
1.56
9.79
3.6
3.0
—
—
—
0
0
196
1245
1.71
9.62
5.3
6.2
1.04
1.04
mmol/l
0.04
181
1157
37
118
3.22
9.54
3.4
1.5
—
—
—
0
0
515
4109
1.51
9.50
14.8
11.3
0.00
0.00
e9/l
0.67
394
3376
966
9005
2.51
9.50
25.1
18.0
3.95
3.97
mmol/l
1.28
951
8833
498
3961
1.51
9.23
5.3
5.3
35.81
36.06
g/l
0.44
474
3740
139
808
1.83
9.23
7.0
8.4
7.74
9.02
mmol/l
1.39
134
778
285
2011
1.58
9.17
3.2
2.7
5.28
6.05
e6/l
0.51
255
1835
431
3354
1.50
8.73
3.7
3.6
26.93
51.94
ng/l
0.73
312
2322
57
243
2.43
8.57
3.7
3.1
2.38
2.18
index
0.10
37
136
294
2130
1.54
8.28
2.6
1.8
1.33
1.16
mg/l
0.34
239
1643
579
4828
1.46
7.99
7.5
7.0
10.94
11.77
umol/l
0.92
549
4620
38
137
2.84
7.98
1.4
1.2
3.84
4.64
u/ml
0.14
19
56
531
4383
1.44
7.56
8.1
6.7
2.95
2.87
%
0.30
502
4124
239
1688
1.54
7.46
3.6
3.8
342.97
455.22
ng/l
0.26
177
1259
530
4388
1.43
7.33
8.2
6.8
8.87
8.79
%
0.29
505
4135
529
4379
1.43
7.32
8.2
6.8
0.74
0.69
%
1.37
502
4114
22
61
3.66
7.05
1.2
1.1
0.52
0.52
ratio
0.03
15
36
99
564
1.84
7.00
6.9
4.3
23.97
24.28
mmol/l
0.46
99
558
531
4425
1.42
6.93
8.1
6.6
56.78
56.85
%
0.05
511
4244
538
4495
1.42
6.91
8.2
6.7
27.62
28.16
%
0.55
512
4287
169
1121
1.61
6.88
3.7
3.0
8.63
7.31
umol/l
0.37
142
990
110
657
1.76
6.65
2.2
2.5
32.49
19.39
au/ml
0.57
11
64
614
5295
1.40
6.32
11.7
10.0
3.93
4.05
e9/l
0.70
518
4633
982
9392
2.40
6.08
26.2
19.7
75.30
75.60
umol/l
0.10
971
9302
288
2197
1.43
5.96
3.8
3.7
—
0.13
—
0
23
145
959
1.60
5.95
2.3
2.1
377.23
373.14
nmol/l
0.10
138
906
472
3922
1.38
5.92
2.0
2.1
95.58
96.45
pmol/l
0.15
242
2119
24
80
3.05
5.83
3.5
3.6
12.89
12.12
index
0.18
18
57
766
6916
1.44
5.74
9.0
8.5
78.37
78.71
u/l
0.08
736
6572
705
6301
1.39
5.38
3.8
3.4
45.92
47.34
u/l
0.17
673
5977
38
168
2.31
5.36
1.7
1.3
82.66
58.81
mmol/l
1.78
32
144
182
1296
1.49
5.33
2.6
2.6
24.57
23.07
%
0.56
169
1225
338
2700
1.38
5.24
1.4
1.5
—
—
—
0
0
568
4921
1.35
5.19
4.0
3.8
0.01
0.34
estimate
0.52
108
935
193
1406
1.46
5.03
2.5
2.6
2.25
2.34
g/l
1.25
177
1316
132
890
1.56
4.98
6.4
4.2
1.38
1.93
mmol/l
0.77
124
763
26
100
2.64
4.92
2.7
2.3
—
—
—
0
0
563
4894
1.34
4.91
4.0
3.7
14.56
4.74
estimate
0.29
113
1009
261
2016
1.40
4.91
1.5
1.5
2.39
2.42
g/l
0.07
165
1259
557
4842
1.33
4.82
4.0
3.7
0.01
0.00
estimate
0.42
113
990
18
57
3.20
4.78
3.8
3.8
0.72
0.91
index
0.76
18
57
12
21
5.77
4.76
1.1
1.0
6.31
5.97
mg/g
0.11
12
21
135
925
1.53
4.73
6.3
4.2
7.39
7.38
ph
0.37
69
525
12
22
5.51
4.61
1.1
1.0
—
—
—
0
0
884
8296
1.51
4.60
6.0
5.3
1.77
1.89
mu/l
2.55
832
7735
229
1748
1.40
4.59
2.9
2.8
2.43
2.44
mmol/l
0.69
198
1585
378
3125
1.33
4.55
3.8
3.6
2.36
2.35
mmol/l
0.06
345
2864
185
1369
1.43
4.40
1.4
1.4
269.68
486.26
titre
3.62
31
294
971
9345
1.90
4.31
14.0
12.1
27.09
26.38
u/l
0.25
943
9120
199
1509
1.40
4.11
2.6
2.6
13.57
13.43
umol/l
0.09
185
1416
105
704
1.55
4.07
1.9
2.4
5.56
7.40
ug/l
0.71
91
640
66
396
1.71
3.99
1.3
1.2
—
—
—
0
0
457
3933
1.29
3.96
3.5
3.3
6.29
6.19
ph
0.98
238
2239
324
2666
1.32
3.91
3.2
2.9
0.40
0.04
—
5
51
179
1344
1.40
3.91
2.3
2.1
—
—
—
0
0
110
760
1.50
3.73
3.6
3.0
73.43
73.16
e9/l
0.02
71
563
138
1001
1.44
3.65
3.5
3.0
1.85
1.84
%
0.04
125
916
112
785
1.48
3.54
4.2
2.9
10.32
10.67
g/l
0.36
100
733
16
57
2.84
3.53
1.5
1.4
170.28
175.39
pmol/l
0.08
16
57
504
4436
1.27
3.51
3.5
3.1
124.66
120.91
ug/l
0.12
474
4178
99
682
1.50
3.41
3.6
4.1
1.22
1.23
mmol/l
0.95
87
588
102
709
1.49
3.37
3.2
4.1
72.87
83.89
ng/l
0.85
90
631
334
2807
1.28
3.35
8.6
6.3
—
—
—
0
0
306
2546
1.29
3.32
1.6
1.7
21.09
20.14
nmol/l
0.51
266
2178
10
23
4.38
3.31
1.6
1.7
17.94
17.76
umol/l
—
10
23
377
3226
1.27
3.25
4.0
3.4
34.02
32.29
u/l
0.22
364
3063
8
15
5.37
3.19
1.1
1.2
—
—
—
0
0
284
2356
1.29
3.12
2.5
2.3
2.59
2.84
mg/l
1.42
239
2045
277
2297
1.28
3.05
1.3
1.3
0.95
1.47
u/ml
0.78
74
636
167
1291
1.35
3.04
1.3
1.2
—
—
—
0
0
146
1105
1.38
3.04
1.8
1.7
—
—
—
0
0
64
411
1.59
3.04
2.5
2.3
—
—
—
0
0
122
896
1.41
3.03
2.6
2.5
0.22
0.21
g/l
0.07
113
844
77
519
1.52
2.97
1.8
1.4
29.73
26.77
iu/l
0.29
67
444
93
653
1.47
2.94
5.9
4.1
5.17
5.14
kpa
0.16
88
634
91
639
1.47
2.88
6.0
4.1
7.42
7.42
ph
0.04
75
527
989
9662
1.92
2.83
32.5
23.4
252.45
252.40
e9/l
0.01
974
9493
989
9663
1.92
2.81
32.3
23.4
90.89
90.88
fl
0.04
982
9582
163
1271
1.34
2.80
2.0
2.5
162.64
108.71
ug/g
0.51
132
1030
989
9666
1.90
2.76
32.3
23.3
30.29
30.30
pg
0.03
982
9584
989
9666
1.90
2.76
33.8
24.0
40.22
40.53
%
1.31
982
9579
989
9666
1.90
2.76
32.4
23.4
4.47
4.52
e12/l
2.33
973
9473
989
9668
1.90
2.73
32.6
23.6
134.33
135.96
g/l
3.00
983
9586
989
9668
1.90
2.73
32.4
23.5
6.63
6.70
e9/l
0.54
973
9468
14
54
2.61
2.71
1.1
1.4
23.24
26.31
umol/l
0.13
14
47
37
212
1.77
2.70
1.2
1.2
—
—
—
0
0
18
80
2.27
2.61
2.1
1.4
—
—
—
0
0
88
627
1.44
2.61
2.1
1.9
1.18
1.36
g/l
0.66
80
582
30
163
1.87
2.60
2.3
1.7
0.64
0.84
g/l
0.71
24
132
58
380
1.56
2.57
1.2
1.2
0.26
1.37
u/ml
—
7
23
8
21
3.83
2.46
1.3
1.1
—
—
—
0
0
12
45
2.69
2.45
1.3
4.0
156.20
124.56
umol/l
—
5
27
465
4168
1.21
2.42
2.5
2.5
76.56
76.38
nmol/l
0.04
423
3796
8
22
3.66
2.36
1.3
1.5
—
—
—
0
0
23
119
1.95
2.32
1.7
1.8
21.04
34.58
ng/l
0.73
23
119
796
7548
1.25
2.29
27.5
18.9
13.57
13.56
%
0.08
791
7462
101
756
1.37
2.28
1.4
1.5
—
—
—
0
0
36
216
1.69
2.28
3.1
2.3
131.25
130.89
g/l
0.02
24
170
103
774
1.37
2.27
1.2
1.2
—
—
—
0
0
144
1138
1.31
2.27
1.4
1.6
—
—
—
0
0
39
240
1.65
2.25
7.6
4.0
60.87
60.92
%
0.00
39
232
46
296
1.58
2.23
2.1
1.3
12.01
9.24
u/l
0.42
36
235
19
94
2.04
2.17
2.8
1.3
0.49
0.34
g/l
0.87
14
71
19
94
2.04
2.17
2.8
1.3
7.05
6.74
g/l
0.18
14
72
19
94
2.04
2.17
2.8
1.3
3.24
2.86
g/l
0.45
14
70
54
366
1.50
2.09
2.0
1.8
2.99
2.12
ug/l
0.21
46
335
16
75
2.15
2.09
2.2
1.3
125111.40
27784.35
e6/l
—
10
37
105
804
1.34
2.07
1.4
1.4
—
—
—
0
0
748
7081
1.21
2.00
4.9
4.4
14.72
14.72
pmol/l
0.02
703
6547
39
249
1.59
1.98
5.7
8.6
1.26
1.29
mmol/l
0.09
34
223
50
338
1.50
1.98
1.3
1.2
—
—
—
0
0
104
802
1.33
1.97
3.7
5.2
0.00
0.16
%
2.18
22
208
6
16
3.77
1.93
2.5
3.3
31.33
31.81
%
—
6
16
6
16
3.77
1.93
5.0
6.5
5.33
10.63
%
—
6
16
11
45
2.46
1.93
1.0
3.5
765.91
711.96
u/ml
0.10
11
45
9
33
2.74
1.93
1.3
1.6
—
—
—
0
0
16
78
2.07
1.91
2.1
1.8
—
—
—
0
0
217
1840
1.23
1.91
1.9
1.9
—
—
—
0
0
78
578
1.38
1.91
4.2
3.8
4.44
4.64
pmol/l
0.96
73
521
37
236
1.59
1.89
1.2
1.2
29.34
37.85
u/ml
—
7
25
147
1195
1.27
1.88
1.5
1.5
—
—
—
0
0
91
693
1.34
1.88
1.4
1.2
91.15
143.52
u/ml
0.89
33
284
15
72
2.10
1.87
2.3
1.3
—
—
—
0
0
46
312
1.50
1.81
2.4
1.8
44.54
39.37
nmol/l
0.49
46
298
30
184
1.65
1.80
7.9
3.4
—
—
—
0
0
18
95
1.91
1.76
2.9
1.3
—
—
—
0
0
79
596
1.35
1.75
1.9
2.8
—
—
—
0
0
181
1521
1.23
1.74
1.6
1.7
—
—
—
0
0
27
163
1.67
1.72
1.1
1.1
—
—
—
0
0
11
48
2.31
1.71
9.5
9.0
8.28
336.76
ug/l
—
6
34
105
829
1.30
1.70
3.6
4.9
1.18
1.03
%
0.09
28
271
145
1193
1.25
1.69
1.3
1.3
—
—
—
0
0
78
594
1.34
1.64
2.2
3.0
168.55
170.84
ng/l
0.02
69
542
329
2940
1.18
1.63
3.0
2.6
64.49
60.96
u/l
0.22
299
2734
5
14
3.58
1.61
1.0
1.1
—
—
—
0
0
99
784
1.29
1.58
3.6
5.0
0.09
0.11
%
0.13
22
226
11
50
2.21
1.57
1.0
1.3
144.64
146.59
nmol/l
0.03
11
50
16
85
1.90
1.55
2.2
1.3
1523.60
1964.88
e6/l
—
10
52
12
57
2.12
1.55
1.3
1.9
30.33
28.34
umol/l
0.22
12
50
92
725
1.30
1.53
3.5
3.7
—
—
—
0
0
100
797
1.28
1.53
3.5
4.7
0.63
0.62
%
0.02
26
251
89
700
1.30
1.51
1.3
1.3
240.24
224.91
u/ml
0.05
81
648
10
45
2.23
1.46
1.2
1.4
153.10
187.08
mmol/24h
—
10
45
297
2653
1.17
1.46
3.9
3.9
0.00
0.01
estimate
1.34
106
935
7
28
2.51
1.45
3.0
3.3
—
—
—
0
0
7
28
2.51
1.45
3.4
1.7
—
—
—
0
0
13
66
1.98
1.43
1.2
1.7
10.91
12.85
umol/l
0.51
13
61
25
157
1.61
1.41
9.3
3.7
2.51
2.42
mmol/l
0.04
14
110
26
165
1.59
1.41
1.5
1.5
0.23
0.35
nmol/l
0.91
18
136
9
40
2.26
1.40
3.6
2.4
—
—
—
0
0
42
297
1.43
1.39
1.6
1.5
325.80
288.37
ug/g
0.70
30
181
210
1830
1.19
1.39
1.3
1.3
15.85
32.45
iu/ml
4.23
49
546
39
272
1.45
1.39
1.5
1.1
—
—
—
0
0
52
383
1.38
1.38
1.5
2.1
1.26
1.48
g/l
1.04
44
341
55
409
1.36
1.38
1.8
1.8
8.31
6.90
iu/ml
0.17
13
99
861
8350
1.21
1.35
6.3
6.2
38.26
39.03
mmol/mol
2.10
819
7880
14
75
1.88
1.34
1.8
1.1
—
—
—
0
0
16
90
1.79
1.33
7.0
5.6
50.70
45.74
u/ml
—
6
34
7
149
0.47
1.32
3.7
3.3
0.74
0.84
nmol/l
—
7
124
190
1652
1.18
1.30
3.4
3.2
0.69
0.76
ug/l
0.62
133
1039
421
3887
1.14
1.29
2.1
1.9
1.33
1.36
mmol/l
0.24
364
3311
20
122
1.65
1.28
2.9
2.4
1.01
0.95
%
0.17
15
83
99
808
1.25
1.27
3.3
2.3
14.35
13.27
nmol/l
0.46
92
734
88
709
1.26
1.26
3.1
2.4
6.30
6.09
ph
1.20
52
474
50
373
1.36
1.25
7.3
4.7
25.27
24.76
mmol/l
0.63
43
355
26
173
1.52
1.19
1.3
1.7
—
—
—
0
0
12
64
1.89
1.18
1.0
1.0
—
—
—
0
0
280
2530
1.15
1.17
3.1
3.1
872.17
1053.13
ng/l
0.60
246
2146
914
8941
1.22
1.14
6.0
5.7
2.70
2.74
mmol/l
0.68
861
8391
51
388
1.33
1.14
1.3
1.5
—
—
—
0
0
12
65
1.86
1.13
6.0
2.1
30.71
34.57
mg/l
—
7
46
267
2410
1.15
1.13
2.9
2.8
327.04
339.25
umol/l
1.17
236
2146
51
390
1.32
1.10
1.3
1.5
—
—
—
0
0
20
128
1.57
1.09
1.0
1.9
—
1744.00
—
0
5
7
32
2.20
1.08
3.0
3.0
—
—
—
0
0
51
393
1.31
1.06
1.3
1.5
—
—
—
0
0
28
196
1.44
1.03
1.1
1.8
—
—
—
0
0
18
114
1.59
1.03
1.3
1.3
—
—
nmol/l
—
0
0
46
353
1.32
0.99
2.5
2.3
2196.19
6001.30
u/l
0.90
18
144
47
362
1.31
0.99
1.3
1.5
—
—
—
0
0
5
23
2.18
0.98
1.2
1.3
28.80
27.96
s
—
5
23
5
23
2.18
0.98
1.0
1.2
—
—
—
0
0
14
84
1.68
0.98
1.2
1.2
0.13
4.85
u/ml
—
5
42
58
461
1.27
0.97
7.0
4.3
—
—
—
0
0
874
8539
1.17
0.97
5.0
5.0
5.85
5.91
mmol/l
0.70
815
7927
18
116
1.56
0.97
3.7
2.3
32.06
32.74
pg
0.28
18
116
17
108
1.58
0.97
1.5
1.4
—
—
—
0
0
9
51
1.77
0.94
1.0
1.2
—
—
—
0
0
861
8407
1.16
0.94
4.5
4.3
1.28
1.30
mmol/l
0.43
805
7814
39
296
1.33
0.92
1.3
1.5
—
—
—
0
0
59
474
1.26
0.92
1.3
1.2
—
—
—
0
0
14
86
1.64
0.91
1.1
1.2
—
—
—
0
0
11
63
1.75
0.90
1.1
1.2
—
—
—
0
0
20
135
1.49
0.89
1.2
1.0
0.46
0.44
u/ml
—
10
48
20
135
1.49
0.89
1.1
1.2
—
—
—
0
0
103
881
1.19
0.89
1.9
2.1
0.00
0.03
estimate
0.78
23
188
18
119
1.52
0.88
1.4
1.3
—
—
—
0
0
236
2148
1.13
0.88
4.6
4.9
—
—
—
0
0
33
246
1.35
0.88
1.5
1.8
—
—
—
0
0
113
977
1.18
0.86
1.6
1.7
—
—
—
0
0
391
3667
1.11
0.86
4.0
3.6
0.07
0.02
estimate
0.50
90
819
24
170
1.42
0.86
1.2
1.1
—
—
—
0
0
21
146
1.45
0.83
1.1
1.1
3.30
4.71
u/ml
0.24
12
61
8
46
1.74
0.82
1.0
1.1
121.19
227.76
iu/ml
—
8
46
91
776
1.19
0.82
2.4
2.4
0.51
0.42
e6/l
0.22
86
743
49
393
1.26
0.80
1.3
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.3
—
26.50
—
0
16
13
82
1.59
0.78
1.2
1.3
—
—
—
0
0
5
98
0.51
0.78
1.2
1.1
—
—
—
0
0
6
34
1.77
0.76
2.2
1.9
36.10
41.47
g/l
—
6
34
25
183
1.38
0.76
1.2
1.1
7.66
4.80
u/ml
0.37
15
97
25
183
1.38
0.76
1.2
1.6
176.36
149.93
au/ml
1.17
11
55
12
75
1.61
0.75
1.2
1.1
—
100.40
—
0
5
184
1670
1.12
0.73
1.3
1.3
12.36
11.43
u/ml
0.06
83
655
46
371
1.25
0.73
1.5
1.6
27.15
11.31
u/ml
0.51
11
85
22
159
1.39
0.72
1.2
1.0
3.37
4.91
u/ml
0.22
13
78
20
142
1.42
0.72
2.5
1.8
—
—
—
0
0
11
68
1.62
0.72
1.0
1.0
—
—
—
0
0
7
41
1.71
0.70
49.7
38.8
132.14
137.67
ug/l
—
7
36
17
118
1.45
0.69
1.4
1.3
0.13
0.18
nmol/l
—
10
89
55
456
1.22
0.69
1.5
1.6
0.35
0.35
mg/l
0.04
24
212
898
8834
1.14
0.68
5.3
5.1
4.62
4.67
mmol/l
0.68
845
8322
18
127
1.42
0.68
5.8
2.6
—
—
—
0
0
125
1113
1.14
0.68
1.4
1.4
—
—
—
0
0
338
3182
1.09
0.67
3.4
3.5
8.10
7.81
mmol/l
0.47
286
2726
24
181
1.33
0.63
1.2
1.1
0.06
1.51
u/ml
2.74
11
97
13
87
1.50
0.63
1.9
1.4
6.75
6.23
mmol/l
0.19
13
82
34
270
1.27
0.63
1.9
2.0
2.10
4.11
iu/l
2.47
11
112
19
138
1.38
0.62
2.7
2.7
—
—
—
0
0
6
102
0.59
0.62
1.8
2.3
—
—
—
0
0
5
30
1.67
0.61
1.2
1.6
30.80
98.00
nmol/24h
—
5
30
96
1085
0.87
0.61
1.9
1.7
—
—
—
0
0
13
88
1.48
0.60
2.3
2.6
1.20
1.19
mmol/l
0.27
13
88
0
20
0.00
0.60
0.0
8.1
—
5.21
—
0
20
11
72
1.53
0.59
1.4
1.6
9.60
31.08
%
—
5
48
27
210
1.29
0.59
1.1
1.1
2.91
2.61
u/ml
0.05
17
120
0
23
0.00
0.58
0.0
1.1
—
138.06
—
0
18
0
23
0.00
0.58
0.0
3.0
—
—
—
0
0
13
89
1.47
0.58
2.3
2.6
105.69
105.02
mmol/l
0.34
13
89
13
89
1.47
0.58
2.3
2.6
4.08
4.07
mmol/l
0.09
13
89
20
149
1.35
0.58
4.9
3.6
3.84
4.30
e9/l
0.36
20
149
316
2988
1.08
0.56
4.1
4.2
7.28
8.07
mg/mmol
0.15
191
1875
10
65
1.54
0.55
1.3
1.2
5.06
5.99
ug/l
—
10
53
6
37
1.63
0.55
1.8
1.1
28.77
32.87
nmol/l
—
6
27
25
195
1.29
0.54
1.3
1.2
—
—
—
0
0
51
433
1.19
0.53
3.9
3.2
1.02
1.02
ratio
0.43
43
406
22
169
1.31
0.53
1.6
1.6
—
—
—
0
0
309
2930
1.08
0.51
3.6
3.5
49.82
47.12
mg/l
0.05
193
1900
25
198
1.27
0.49
1.2
1.6
—
—
—
0
0
14
101
1.39
0.49
1.4
1.7
68.67
60.99
%
—
6
68
7
48
1.46
0.47
1.6
2.0
1.69
1.92
umol/l
—
7
40
7
48
1.46
0.47
1.0
3.5
16.76
17.32
%
—
7
48
30
364
0.82
0.47
1.1
1.1
1.53
1.54
g/l
0.03
30
364
31
255
1.22
0.46
1.1
1.2
—
—
—
0
0
18
138
1.31
0.45
3.2
1.6
—
—
—
0
0
18
138
1.31
0.45
3.2
1.6
—
—
—
0
0
18
138
1.31
0.45
3.2
1.6
—
—
—
0
0
18
138
1.31
0.45
3.2
1.6
—
—
—
0
0
5
85
0.59
0.45
1.4
1.1
—
—
—
0
0
25
201
1.25
0.45
4.5
3.3
57.46
57.48
%
0.00
25
201
7
50
1.40
0.45
1.0
1.1
—
—
—
0
0
19
242
0.78
0.45
1.5
1.6
5296.00
13491.98
e6/l
—
8
175
54
470
1.16
0.44
1.6
2.2
0.00
1.63
estimate
0.51
19
156
10
69
1.45
0.44
3.0
2.8
1097.00
1018.77
mg
—
10
69
44
511
0.85
0.44
1.8
1.7
—
—
—
0
0
194
1819
1.08
0.43
1.7
1.7
432.15
31572511.76
pmol/l
1.91
164
1533
22
175
1.26
0.43
1.1
1.1
1.32
1.58
u/ml
0.07
12
78
132
1217
1.10
0.43
3.5
3.3
3.93
5.14
e9/l
1.46
115
1073
891
8804
1.10
0.43
5.2
5.0
1.46
1.46
mmol/l
0.07
838
8246
12
162
0.74
0.42
1.1
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
70.25
—
0
16
0
17
0.00
0.40
0.0
2.0
—
3.06
—
0
17
84
927
0.90
0.40
1.4
1.4
—
—
—
0
0
285
2721
1.07
0.39
5.6
5.3
1.86
2.34
ug/l
1.35
261
2476
358
3719
0.94
0.39
3.1
3.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
11
80
1.38
0.38
1.1
1.2
—
—
—
0
0
5
36
1.39
0.38
1.0
2.9
22.34
239.49
ug/l
—
5
31
5
36
1.39
0.38
2.4
1.6
—
—
—
0
0
39
336
1.17
0.38
2.7
2.7
—
—
—
0
0
9
69
1.31
0.37
1.7
1.6
—
—
—
0
0
5
37
1.35
0.37
1.6
1.5
—
—
—
0
0
148
1385
1.08
0.36
1.7
1.7
1036.59
1194.81
nmol/l
1.46
110
1047
31
263
1.18
0.36
1.9
4.0
2.16
2.53
ratio
0.15
17
154
22
180
1.23
0.36
3.5
3.3
7.51
8.68
pmol/l
0.29
22
180
99
915
1.09
0.33
4.1
4.7
11.12
23.91
ug/l
0.69
72
757
6
46
1.31
0.33
1.0
1.1
1.02
1.06
ratio
—
6
39
43
380
1.14
0.31
4.0
3.5
25.52
25.24
mmol/l
0.25
43
370
36
411
0.87
0.31
1.5
1.6
1238.61
961.32
mu/l
0.61
31
350
90
831
1.09
0.31
3.1
4.2
7.37
7.36
ph
0.29
66
611
74
803
0.92
0.28
1.6
1.7
3.25
3.52
mmol/l
1.21
51
584
8
62
1.29
0.28
1.4
1.5
84.25
78.48
umol/l
—
8
62
9
116
0.77
0.27
1.0
1.1
—
—
—
0
0
100
1068
0.93
0.27
1.9
2.0
3.47
3.51
ratio
0.10
76
846
34
382
0.89
0.25
1.3
1.2
0.84
0.90
g/l
1.03
34
382
44
397
1.11
0.25
2.0
1.8
—
—
—
0
0
11
87
1.27
0.24
8.2
2.4
38.46
37.87
%
0.05
11
87
15
180
0.83
0.24
1.0
1.2
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
23
200
1.15
0.22
3.3
2.3
91.91
102.81
ug/min
0.08
12
121
24
210
1.15
0.22
4.5
3.0
1.32
1.56
mmol/l
1.37
24
205
5
42
1.19
0.21
3.8
1.8
107.80
60.95
ug/l
—
5
42
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
274
2661
1.04
0.21
3.5
3.1
0.04
0.04
estimate
0.01
89
803
0
12
0.00
0.21
0.0
1.0
—
173.08
—
0
12
5
43
1.16
0.21
1.2
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
10.09
—
0
6
10
80
1.25
0.20
1.0
1.1
91.80
111.26
pmol/l
—
10
80
6
48
1.25
0.20
1.2
1.3
529.50
502.19
u/l
—
6
43
12
99
1.21
0.19
1.0
1.1
—
—
—
0
0
12
100
1.20
0.18
7.2
4.3
—
—
—
0
0
12
142
0.84
0.17
1.0
1.1
2.91
1.98
eliau/ml
—
7
60
23
205
1.12
0.17
1.3
1.3
256.33
261.13
u/ml
0.03
18
113
5
66
0.76
0.17
1.0
1.1
477.00
394.48
nmol/l
—
5
58
70
663
1.06
0.15
1.3
1.2
—
—
—
0
0
102
978
1.05
0.15
1.6
1.5
—
—
—
0
0
220
2147
1.03
0.14
4.1
3.8
1.02
1.02
kg/l
0.18
143
1443
15
170
0.88
0.13
6.7
4.2
32.87
30.47
u/ml
0.06
15
165
17
189
0.90
0.12
1.4
1.5
—
—
—
0
0
35
374
0.93
0.11
1.1
1.1
—
—
—
0
0
17
187
0.91
0.10
1.4
1.4
1.31
1.28
mm
0.10
11
143
26
242
1.08
0.09
1.3
1.5
71.59
60.31
ug/l
0.39
20
212
11
97
1.14
0.09
1.3
1.1
—
—
—
0
0
107
1097
0.97
0.08
1.3
1.5
—
—
—
0
0
26
244
1.07
0.08
1.3
1.3
—
—
—
0
0
8
76
1.05
0.07
1.5
1.2
—
—
—
0
0
8
78
1.03
0.07
1.1
1.1
—
—
—
0
0
9
87
1.03
0.07
1.4
2.6
—
—
—
0
0
29
275
1.06
0.06
1.9
1.9
—
—
—
0
0
8
95
0.84
0.06
4.4
2.6
—
—
—
0
0
34
325
1.05
0.06
1.2
1.3
205.53
256.80
miu/ml
0.45
19
149
16
172
0.93
0.06
1.6
1.7
—
—
—
0
0
18
192
0.94
0.05
1.3
1.6
—
—
—
0
0
15
159
0.94
0.03
1.9
1.8
—
—
—
0
0
17
161
1.06
0.03
1.2
1.2
—
—
—
0
0
21
201
1.05
0.03
5.7
4.2
—
—
—
0
0
11
102
1.08
0.03
3.6
3.8
60.36
54.39
%
0.55
11
93
26
251
1.04
0.02
1.2
1.1
—
—
—
0
0
27
261
1.04
0.02
1.3
2.4
10.85
11.54
mg/l
0.17
27
242
27
264
1.02
0.00
13.7
9.5
—
—
—
0
0
33
324
1.02
0.00
1.3
1.3
—
—
—
0
0
12
122
0.98
0.00
2.1
2.5
—
23.08
—
0
12
53
526
1.01
0.00
1.0
1.1
—
—
—
0
0
20
202
0.99
0.00
1.0
1.1
—
—
—
0
0
10
97
1.03
0.00
2.0
2.1
—
—
—
0
0
20
201
0.99
0.00
1.0
1.1
—
—
—
0
0
34
343
0.99
0.00
3.0
4.1
397.80
314.79
mg/l
0.16
20
149
12
115
1.04
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
6.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
494.18
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.06
—
0
6
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
6
64
0.94
0.00
1.0
1.0
750.83
667.62
ng/l
—
6
45
5
50
1.00
-0.00
1.2
3.7
—
54.51
—
0
9
0
5
0.00
-0.00
0.0
1.6
—
0.14
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
2.6
1.9
68.40
109.34
ng/l
—
5
58
0
7
0.00
-0.00
0.0
2.6
—
189.29
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
358.29
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
270.56
—
0
9
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM and mortality.

Females

Parameter HR [95% CI] p-value
Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM 1.412 [1.2, 1.67] < 0.001
Birth year 0.995 [0.99, 1.0] 0.218

During the follow-up period (1.1.1998 — 31.12.2019), 247 out of 2415 females with Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM died.

Males

Parameter HR [95% CI] p-value
Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM 1.509 [1.28, 1.78] < 0.001
Birth year 0.989 [0.98, 1.0] 0.02

During the follow-up period (1.1.1998 — 31.12.2019), 309 out of 2209 males with Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM died.

Mortality risk

Mortality risk for people of age

years, who have Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM.

N-year risk Females Males
1 0.111% 0.301%
5 0.689% 1.751%
10 1.803% 4.426%
15 3.836% 8.529%
20 6.932% 14.452%

Relationships between endpoints

Index endpoint: Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM – Other congenital malformations of circulatory system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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