hyperpituitarism: Disease of the glandular, anterior portion of the pituitary (pituitary gland, anterior) resulting in hypersecretion of adenohypophyseal hormones such as growth hormone; prolactin; thyrotropin; luteinizing hormone; follicle stimulating hormone ; and adrenocorticotropic hormone. Hyperpituitarism usually is caused by a functional adenoma.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2076 |
4. Check minimum number of eventsNone |
2076 |
5. Include endpoints |
2279 |
6. Filter based on genotype QC (FinnGen only) |
2020 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E20-E35
- Name in latin
- Hyperfunctio hypophysis
Similar endpoints
↥List of similar endpoints to
Hyperfunction of pituitary gland
based on the number of shared cases.
Similar with more cases:
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13775 | 10007 | 3602 |
| Only index persons | 12382 | 9265 | 3117 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.24 | 0.29 | 0.10 |
| Only index persons | 0.28 | 0.34 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 36.03 | 32.93 | 44.58 |
| Only index persons | 35.04 | 32.51 | 42.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2020 | 1522 | 498 |
| Unadjusted period prevalence (%) | 0.46 | 0.54 | 0.23 |
| Median age at first event (years) | 38.86 | 34.93 | 50.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2122
- Matched controls
- 21220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E22.1
ICD-10 Finland
Hyperprolactinaemia
7969.7
307.7
1425
6
G02CB03
ATC
cabergoline; oral
68.1
307.7
220
36
G02CB01
ATC
bromocriptine; systemic
39.6
307.7
505
166
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
288.3
307.7
615
30
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
213.0
307.7
466
28
N04BC06
ATC
cabergoline; oral
734.8
307.7
546
10
H02AB09
ATC
hydrocortisone; systemic
23.1
307.7
281
139
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
+∞
239.2
225
*
E22.2
ICD-10 Finland
Syndrome of inappropriate secretion of antidiuretic hormone
1083.7
204.7
197
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
214.4
172.9
177
9
N91.1
ICD-10 Finland
Secondary amenorrhoea
10.5
166.6
190
196
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
159.4
151
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
8.5
151.3
205
264
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
32.4
115.8
75
24
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
114.6
109
*
E22.80
ICD-10 Finland
Central precocious puberty
+∞
104.0
99
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
6.8
102.4
166
260
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
160.9
102.2
107
7
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
56.4
97.1
55
10
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.0
91.2
283
778
N05AX08
ATC
risperidone; systemic
3.9
87.3
288
826
ZXC86
NOMESCO Finland
Use of endoscopic device
36.2
84.5
53
15
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
5.5
81.0
165
322
G02CB04
ATC
quinagolide; oral
237.6
67.6
69
*
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
668.5
66.3
65
*
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
12.9
65.9
64
51
G03DB01
ATC
dydrogesterone; oral
2.7
64.3
428
1839
N05AH03
ATC
olanzapine; systemic
3.5
64.1
246
775
H03AA01
ATC
levothyroxine sodium; systemic
2.3
61.0
611
3158
N64.3
ICD-10 Finland
Galactorrhoea not associated with childbirth
10.1
54.4
62
63
E22.9
ICD-10 Finland
Hyperfunction of pituitary gland, unspecified
+∞
54.4
52
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.0
54.1
164
439
H01CB02
ATC
octreotide; parenteral
101.1
54.1
59
6
2531A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Other and unspecified anterior pituitary hyperfunction[HYPERPROLACTINAEMIA]
+∞
51.2
49
*
N05AX12
ATC
aripiprazole; systemic
3.5
51.2
188
573
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
135.8
50.0
53
*
2594A
ICD-9 Finland
Other endocrine disorders, Dwarfism, not elsewhere classified
+∞
48.1
46
*
N05AH02
ATC
clozapine; systemic
5.5
47.1
92
172
E23.05
ICD-10 Finland
Lack of TSH
240.2
46.2
47
*
2273A
ICD-9 Finland
Benign neoplasm of other endocrine glands and related structures, Pituitary gland and craniopharyngeal duct (pouch)
+∞
46.0
44
*
102
Kela drug reimbursment
Diabetes insipidus
457.3
45.4
45
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
10.9
45.4
49
46
N05AB03
ATC
perphenazine; systemic, rectal
4.0
43.2
127
332
XCK00
NOMESCO Finland
Perimetry
3.5
42.9
152
452
H01AC01
ATC
somatropin; parenteral
+∞
41.8
40
*
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
41.8
40
*
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
5.3
41.3
84
163
H01CB03
ATC
lanreotide; parenteral
76.7
40.0
45
6
N05AH04
ATC
quetiapine; oral
2.1
39.8
493
2708
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
203.7
38.9
40
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.6
38.4
245
1015
N05AA02
ATC
levomepromazine; systemic
3.8
38.1
121
334
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
5.1
37.0
79
160
2530A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Acromegaly and gigantism[ACROMEGALIA]
+∞
35.5
34
*
XLA10, ,
NOMESCO Finland
3.1
34.7
151
509
E30.1
ICD-10 Finland
Precocious puberty
342.5
34.0
34
*
N04AA02
ATC
biperiden; systemic
5.1
32.7
70
142
AA1AD
NOMESCO Finland
CT of head and brain
1.9
32.7
516
3058
N03AG01
ATC
valproic acid; systemic, rectal
2.8
32.3
174
661
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
31.3
30
*
E21.0
ICD-10 Finland
Primary hyperparathyroidism
42.9
30.9
38
9
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
5.3
30.9
62
119
N04BC01
ATC
bromocriptine; oral
162.4
30.7
32
*
N97.0
ICD-10 Finland
Female infertility associated with anovulation
4.2
30.3
81
197
2542
FHL
Transasal hypophysectomy
+∞
30.3
29
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.6
29.4
101
294
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.9
29.3
144
520
N97.9
ICD-10 Finland
Female infertility, unspecified
2.5
28.7
197
842
L02AE02
ATC
leuprorelin; implant, parenteral
3.4
28.6
104
314
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
4.1
27.9
77
192
N05BA06
ATC
lorazepam; systemic, sublingual
3.0
27.6
124
426
UJF32
NOMESCO Finland
Coloscopy
1.8
27.3
473
2867
P72
ICPC
Schizophrenia
4.2
27.1
74
183
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
8.1
26.9
36
45
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
7.3
26.7
39
54
N03AX09
ATC
lamotrigine; oral
2.6
26.4
167
687
E29.1
ICD-10 Finland
Testicular hypofunction
9.8
25.9
30
31
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.1
25.9
114
387
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.0
25.6
305
1631
F20.9
ICD-10 Finland
Schizophrenia, unspecified
4.0
25.1
72
185
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
24.8
759
5364
N05CD07
ATC
temazepam; oral
2.3
24.8
199
911
E23.2
ICD-10 Finland
Diabetes insipidus
253.1
24.7
25
*
N06AB04
ATC
citalopram; systemic
1.8
24.3
447
2750
N06AX16
ATC
venlafaxine; oral
1.9
24.2
371
2157
N05AN01
ATC
lithium; oral
3.5
23.9
85
253
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
23.6
513
3307
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.9
23.4
313
1738
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
23.1
360
2102
25300
ICD-8 Finland
Diseases of pituitary gland, Aeromegalia
+∞
23.0
22
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
23.0
22
*
N05AF05
ATC
zuclopenthixol; systemic
6.8
22.5
35
52
N05AF03
ATC
chlorprothixene; systemic
3.5
22.4
78
229
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
4.7
22.2
52
114
2591A
ICD-9 Finland
Other endocrine disorders, Precocious sexual development and puberty, not elsewhere classified
+∞
21.9
21
*
E22.88
ICD-10 Finland
Other hyperfunction of pituitary gland
+∞
21.9
21
*
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
3.7
21.7
69
191
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
21.4
365
2187
121
Kela drug reimbursment
Severe hypofunction of sexual glands
4.5
21.3
52
118
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.5
21.2
134
550
E23.03
ICD-10 Finland
Lack of ACTH
212.0
20.6
21
*
N05BA04
ATC
oxazepam; oral
1.6
20.2
556
3788
R53
ICD-10 Finland
Malaise and fatigue
1.6
20.2
576
3959
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
20.1
465
3030
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
20.0
811
6052
D352, E221,
ICD-10 Finland
+∞
19.8
19
*
2590A
ICD-9 Finland
Other endocrine disorders, Delay in sexual development and puberty, not elsewhere classified
+∞
19.8
19
*
E23.6
ICD-10 Finland
Other disorders of pituitary gland
+∞
19.8
19
*
T99
ICPC
Endocr/metab/nutrit disease other
4.4
19.7
49
113
188
Kela drug reimbursment
Psychosis requiring demanding treatment
5.4
19.2
38
72
H53.4
ICD-10 Finland
Visual field defects
4.0
19.2
54
137
F22.0
ICD-10 Finland
Delusional disorder
5.2
19.1
39
76
N91.2
ICD-10 Finland
Amenorrhoea, unspecified
5.4
19.0
37
69
H02AA02
ATC
fludrocortisone; oral
8.1
18.8
25
31
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
18.8
18
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
18.8
253
1404
N06AX11
ATC
mirtazapine; oral
1.5
18.8
711
5207
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
4.8
18.7
42
89
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
18.5
273
1560
ZXC95
NOMESCO Finland
Use of surgical navigator
4.9
18.3
40
83
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
18.3
269
1536
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
18.1
514
3516
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
18.0
485
3276
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
17.8
289
1699
R42
ICD-10 Finland
Dizziness and giddiness
1.7
17.8
429
2816
WVA30, ,
SPAT
2.3
17.8
135
603
ZYC01
NOMESCO Finland
Remote contact by phone
2.2
17.7
158
755
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
181.5
17.5
18
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.1
17.5
72
235
AA400
NOMESCO Finland
Electroconvulsive therapy
5.2
17.2
35
68
N05AA01
ATC
chlorpromazine; systemic, rectal
4.7
17.1
39
84
N05AE04
ATC
ziprasidone; systemic
5.3
17.0
34
65
R11
ICD-10 Finland
Nausea and vomiting
1.9
16.8
212
1149
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
16.6
252
1450
R51.80
ICD-10 Finland
Headache
1.6
16.6
400
2623
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
16.5
872
6798
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
16.5
537
3782
N06AB03
ATC
fluoxetine; oral
1.8
16.4
274
1623
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
15.9
645
4756
N05AD01
ATC
haloperidol; systemic
3.2
15.9
62
196
Z3231
NOMESCO Finland
Registered nurse
1.6
15.8
517
3638
N05CF01
ATC
zopiclone; oral
1.5
15.8
565
4056
R55
ICD-10 Finland
Syncope and collapse
2.0
15.7
187
993
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
15.7
367
2385
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
2.7
15.4
82
309
N06AX21
ATC
duloxetine; oral
1.8
15.1
266
1598
N05BA01
ATC
diazepam; systemic, rectal
1.8
15.0
243
1425
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
15.0
141
687
A55
ICPC
General and Unspecified, Local injection/infiltration
4.7
14.9
34
73
C07AA05
ATC
propranolol; systemic
1.6
14.8
458
3177
T73
ICPC
Neoplasm endocrine other/unspecified
31.9
14.8
19
6
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
14.6
14
*
F83
ICD-10 Finland
Mixed specific developmental disorders
6.4
14.6
24
38
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.3
14.5
109
485
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
151.0
14.5
15
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
151.0
14.5
15
*
Z2446
NOMESCO Finland
Social worker
2.0
14.4
151
767
N05BE01
ATC
buspirone; oral
2.8
14.3
70
253
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
27.4
14.3
19
7
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
3.1
14.2
58
189
F20.3
ICD-10 Finland
Undifferentiated schizophrenia
6.4
14.1
23
36
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.9
14.1
201
1134
A06AD11
ATC
lactulose; oral
1.8
14.0
220
1277
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
3.1
14.0
59
196
C03CA01
ATC
furosemide; systemic
1.6
13.9
366
2444
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
13.8
223
1305
N05AX13
ATC
paliperidone; systemic
5.6
13.8
26
47
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
3.5
13.8
46
132
F25.20
ICD-10 Finland
Schizoaffective syndrome, mixed type with only concomitant bipolar and schizophrenic symptoms
5.3
13.7
27
51
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
13.7
425
2946
N06AG02
ATC
moclobemide; oral
2.5
13.7
85
347
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.9
13.7
170
917
R41.0
ICD-10 Finland
Disorientation, unspecified
3.2
13.6
52
163
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.2
13.6
109
499
301
Kela drug reimbursment
Growth hormone
+∞
13.6
13
*
2599X
ICD-9 Finland
Other endocrine disorders, Unspecified endocrine disorder
+∞
13.6
13
*
P29
ICPC
Psychological sympt/compl other
1.8
13.5
223
1315
G47.3
ICD-10 Finland
Sleep apnoea
1.6
13.4
397
2720
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.0
13.4
159
844
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
13.4
225
1334
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
2.4
13.3
90
382
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
13.3
355
2375
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
4.2
13.2
35
85
N03AE01
ATC
clonazepam; systemic
2.2
13.2
112
524
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
4.7
13.1
30
65
L28
ICPC
Limited function/disability (L)
1.6
13.0
293
1879
SPAT1263
SPAT
Sampling
1.4
13.0
825
6574
A12AA04
ATC
calcium carbonate; oral
5.1
12.9
27
54
J01MA12
ATC
levofloxacin; systemic
1.6
12.9
293
1884
A02BC02
ATC
pantoprazole; systemic
1.4
12.9
1284
11050
XF404
NOMESCO Finland
Ambulatory ECG
2.0
12.8
138
708
N05AL01
ATC
sulpiride; systemic
4.1
12.8
34
83
F60.9
ICD-10 Finland
Personality disorder, unspecified
3.3
12.7
47
144
ZY010
NOMESCO Finland
Hospital outpatient
2.0
12.7
144
752
P98
ICPC
Psychosis NOS/other
4.8
12.6
28
59
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
70.3
12.6
14
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
12.5
752
5921
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
2.6
12.5
72
283
IGY99
NOMESCO Finland
Other psychiatric treatment contact
2.5
12.5
77
313
2592A
ICD-9 Finland
Other endocrine disorders, Carcinoid syndrome
+∞
12.5
12
*
M14.5*E22.0
ICD-10 Finland
Arthropathy associated with acromegaly
+∞
12.5
12
*
106
Kela drug reimbursment
Hypoparathyroidism
+∞
12.5
12
*
ZXY49
NOMESCO Finland
Other health care provider
5.3
12.5
25
48
D35.31
ICD-10 Finland
Cyst in Rathke's pocket
24.5
12.5
17
7
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
12.4
122
605
X21
ICPC
Breast sympt/compl female other
2.7
12.4
68
261
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.1
12.3
125
628
H47.2
ICD-10 Finland
Optic atrophy
14.4
12.3
20
14
7834C
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Lack of expected normal physiological development[HÄIRIINTYNYT PITUUSKASVU]
37.8
12.2
15
*
SPAT1240
SPAT
Therapeutic discussion
1.7
12.1
268
1709
F61.0
ICD-10 Finland
Mixed personality disorders
3.1
12.1
50
164
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
12.1
469
3396
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
12.1
650
5009
127
Kela drug reimbursment
Transplant complication
4.1
12.1
33
82
L17
ICPC
Foot/toe symptom/complaint
1.4
12.1
590
4468
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.1
12.0
109
525
N03AX16
ATC
[U] pregabalin
1.5
11.9
388
2709
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
4.9
11.9
26
54
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
4.7
11.9
27
58
F21
ICD-10 Finland
Schizotypal disorder
5.4
11.8
23
43
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.9
11.8
21
36
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.8
470
3422
N06AB06
ATC
sertraline; oral
1.6
11.7
277
1797
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
11.7
522
3887
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
65.3
11.6
13
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
11.6
151
827
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
11.5
147
799
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
11.5
166
940
H01AX01
ATC
pegvisomant; parenteral
+∞
11.5
11
*
E22
ICD-10 Finland
Hyperfunction of pituitary gland
+∞
11.5
11
*
E23
ICD-10 Finland
Hypofunction and other disorders of pituitary gland
+∞
11.5
11
*
2370A
ICD-9 Finland
Neoplasm of uncertain behaviour of endocrine glands and nervous system, Pituitary gland and craniopharyngeal duct
+∞
11.5
11
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
2.2
11.4
96
448
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
120.7
11.4
12
*
22620
ICD-8 Finland
Benign neoplasm of endocrine glands, Pituitary gland and craniopharyngeal duct (pouch)
120.7
11.4
12
*
25320
ICD-8 Finland
Diseases of pituitary gland, Chromophobe adenoma, pituitary
120.7
11.4
12
*
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
3.3
11.4
43
134
N05AF01
ATC
flupentixol; systemic
3.6
11.3
36
100
N06AB05
ATC
paroxetine; oral
1.9
11.3
133
705
P99
ICPC
Psychological disorders other
2.3
11.2
88
399
N05AC02
ATC
thioridazine; oral
3.1
11.2
47
156
WX882
NOMESCO Finland
High dependency care
2.7
11.2
57
211
WX402
NOMESCO Finland
General anaesthesia
1.5
11.2
443
3218
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
11.2
177
1030
N05AX15
ATC
cariprazine; oral
5.6
11.2
21
38
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.7
11.2
194
1160
E86
ICD-10 Finland
Volume depletion
3.3
11.1
42
131
X05
ICPC
Menstruation absent/scanty
3.0
11.1
49
168
Z94.0
ICD-10 Finland
Kidney transplant status
4.8
11.0
24
50
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
10.9
218
1353
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.4
10.9
71
297
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
10.9
175
1023
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.1
10.9
101
491
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
10.9
59
226
P01
ICPC
Feeling anxious/nervous/tense
1.5
10.8
379
2683
N05AE03
ATC
sertindole; oral
9.6
10.7
21
22
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
10.7
187
1120
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
10.7
242
1552
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
10.7
192
1159
IEV99
NOMESCO Finland
Other psychiatric network intervention
4.2
10.6
28
68
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
5.0
10.5
22
44
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
10.4
386
2762
UKC02
NOMESCO Finland
Cystoscopy
1.7
10.4
202
1244
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
110.6
10.4
11
*
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
+∞
10.4
10
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
+∞
10.4
10
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
10.4
158
908
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
10.4
229
1459
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
3.0
10.4
46
158
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
4.3
10.3
26
61
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
2.3
10.3
76
337
M79.6
ICD-10 Finland
Pain in limb
1.4
10.1
873
7230
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.7
10.1
52
194
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.1
10.1
95
465
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
5.0
10.0
21
42
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
10.0
216
1367
F25.21
ICD-10 Finland
Schizoaffective syndrome, mixed type with prolonged schizophrenic than bipolar symptoms
8.5
10.0
21
25
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
10.0
252
1657
-50
ICPC
Medication/prescr/renewal
2.3
10.0
74
328
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
9.9
616
4837
F31
ICD-10 Finland
Bipolar affective disorder
3.2
9.9
39
125
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
9.9
341
2404
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
9.9
395
2868
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
9.9
263
1753
Y28
ICPC
Limited function/disability (Y)
16.8
9.9
15
9
Z2445
NOMESCO Finland
Psychologist
2.0
9.8
101
511
K59.0
ICD-10 Finland
Constipation
2.0
9.7
105
540
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.0
9.7
41
137
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.9
9.7
45
159
137
Kela drug reimbursment
Uraemia requiring dialysis
5.3
9.6
19
36
ZY000
NOMESCO Finland
Hospital inpatient
3.0
9.6
41
138
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
9.6
70
309
F82
ICD-10 Finland
Specific developmental disorder of motor function
8.4
9.6
20
24
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
4.8
9.5
21
44
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
9.5
104
537
E28.3
ICD-10 Finland
Primary ovarian failure
15.1
9.5
15
10
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.4
9.5
62
260
A06AC51
ATC
ispaghula, combinations; oral
2.1
9.4
88
429
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
9.4
251
1673
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
2.8
9.4
46
167
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
9.4
266
1797
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.7
9.4
171
1036
2598X
ICD-9 Finland
Other endocrine disorders, Other specified endocrine disorders
+∞
9.4
9
*
E30.8
ICD-10 Finland
Other disorders of puberty
+∞
9.4
9
*
D352, E220,
ICD-10 Finland
+∞
9.4
9
*
J01MA02
ATC
ciprofloxacin; systemic
1.4
9.4
632
5022
IER01
NOMESCO Finland
Psychoeducation, group
3.5
9.4
31
89
SPAT1254
SPAT
Administration of medicine
1.6
9.3
262
1766
F23.8
ICD-10 Finland
Other acute and transient psychotic disorders
8.1
9.3
20
25
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.1
9.3
92
458
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
9.3
156
923
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
2.7
9.3
49
185
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
9.1
764
6273
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
2.5
9.1
54
217
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
4.6
9.1
21
46
ZXY60
NOMESCO Finland
2-person team, nurses
4.6
9.1
21
46
SPAT1172
SPAT
Guidance concerning hydration
3.4
9.1
31
91
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
9.0
183
1140
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.8
9.0
136
780
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
2.8
9.0
43
154
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
9.0
158
947
E34.35
ICD-10 Finland
Abnormal growth retardation
36.8
9.0
11
*
N03AX14
ATC
levetiracetam; systemic
2.4
8.9
59
249
A28
ICPC
Limited function/disability NOS
1.6
8.9
221
1448
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
8.9
361
2624
SPAT1153
SPAT
Removal of sutures
1.4
8.9
485
3719
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.8
712
5803
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
8.8
1499
13587
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
4.9
8.8
19
39
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
4.0
8.8
24
60
C07AB07
ATC
bisoprolol; oral
1.3
8.8
681
5519
S18
ICPC
Laceration/cut
1.3
8.8
811
6743
WX730
NOMESCO Finland
Conventional respirator
3.7
8.7
27
74
A46
ICD-10 Finland
Erysipelas
1.6
8.7
205
1327
G04BD04
ATC
oxybutynin; oral, transdermal
2.1
8.7
82
402
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.6
8.7
49
192
L04AA06
ATC
mycophenolic acid; systemic
3.0
8.6
37
125
C03DA01
ATC
spironolactone; oral
1.7
8.6
161
982
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.8
8.6
118
659
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
7.0
8.5
20
29
ICB06, ,
NOMESCO Finland
3.4
8.5
29
85
H05BX01
ATC
cinacalcet; oral
27.6
8.5
11
*
IEY08
NOMESCO Finland
Psychiatric coaching, domestic and community skills
6.4
8.5
21
33
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
8.5
417
3138
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
8.4
146
872
F50.9
ICD-10 Finland
Eating disorder, unspecified
2.9
8.4
38
132
BB1BQ
NOMESCO Finland
Extensive scintigraphy of parathyroid gland, 2 isotopes, SPECT and low-dose CT
90.4
8.4
9
*
E66.8
ICD-10 Finland
Other obesity
1.8
8.4
130
752
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
12.8
8.4
14
11
F20.0
ICD-10 Finland
Paranoid schizophrenia
4.9
8.4
18
37
F05.9
ICD-10 Finland
Delirium, unspecified
3.3
8.4
31
96
A41.9
ICD-10 Finland
Sepsis, unspecified
2.4
8.3
54
226
N02AA05
ATC
oxycodone; systemic
1.5
8.3
234
1577
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
+∞
8.3
8
*
2536X
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Other disorders of neurohypophysis
+∞
8.3
8
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
8.3
285
2003
A11CC03
ATC
alfacalcidol; systemic
3.0
8.3
35
117
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.9
8.3
100
535
N06AA04
ATC
clomipramine; systemic
3.1
8.3
34
112
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
8.3
135
794
F28
ICD-10 Finland
Other nonorganic psychotic disorders
7.1
8.2
19
27
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.5
8.2
275
1923
J01DB01
ATC
cefalexin; oral
1.4
8.2
1679
15549
A02BC01
ATC
omeprazole; systemic
1.4
8.2
459
3528
J01EA01
ATC
trimethoprim; systemic
1.4
8.2
484
3753
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.7
8.2
135
796
K07.24
ICD-10 Finland
Open bite
2.9
8.2
37
129
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
2.7
8.1
43
163
N03AX12
ATC
[U] gabapentin; oral
1.5
8.1
266
1852
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.5
8.1
27
78
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
3.3
8.1
29
88
Z00.8
ICD-10 Finland
Other general examinations
1.7
8.0
160
993
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.8
8.0
110
614
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
8.0
461
3559
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.0
8.0
86
443
SPAT1229
SPAT
Assessment of need for aid
1.9
8.0
101
550
IEY01
NOMESCO Finland
Psychoeducation, individual
3.4
7.9
28
84
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.8
7.9
112
631
A02BC05
ATC
esomeprazole; systemic
1.3
7.9
710
5857
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
3.1
7.9
32
105
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
7.9
154
952
A27
ICPC
Fear of other disease NOS
1.9
7.8
92
489
R60.0
ICD-10 Finland
Localized oedema
1.6
7.8
190
1241
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
2.7
7.7
40
150
N06AX03
ATC
mianserin; oral
2.0
7.7
80
406
SPAT1234
SPAT
Support of social functional capacity
2.0
7.7
80
406
R33
ICD-10 Finland
Retention of urine
1.9
7.7
89
469
E27.0
ICD-10 Finland
Other adrenocortical overactivity
45.1
7.7
9
*
E26.0
ICD-10 Finland
Primary hyperaldosteronism
45.1
7.7
9
*
F23.90
ICD-10 Finland
Acute and transient psychosis, unspecified without acute stress factor
6.4
7.7
19
30
L02AE04
ATC
triptorelin; parenteral
6.4
7.7
19
30
C09CA06
ATC
candesartan; oral
1.4
7.7
408
3107
P03
ICPC
Feeling depressed
1.5
7.7
265
1866
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
7.7
104
579
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.9
7.6
100
551
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.9
7.6
95
515
S06.0
ICD-10 Finland
Concussion
1.6
7.6
203
1353
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
3.1
7.6
30
97
X14
ICPC
Vaginal discharge
2.1
7.6
72
355
E0000UV, ,
ATC
1.3
7.5
819
6922
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
3.5
7.5
25
72
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
3.2
7.5
29
92
U05
ICPC
Urination problems other
2.0
7.5
76
383
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
7.5
301
2180
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.2
7.5
62
289
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
1.9
7.5
85
446
SPAT1260
SPAT
Consultation of another employee
1.4
7.5
297
2147
A07DA03
ATC
loperamide; oral
2.4
7.5
50
213
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.4
7.5
49
207
WZA90
NOMESCO Finland
Other medical or dental certificate
1.4
7.5
456
3550
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
7.4
139
849
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
7.4
397
3024
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.4
286
2056
E34.31
ICD-10 Finland
Short stature, prenatal disorder
80.4
7.4
8
*
S10
ICPC
Boil/carbuncle
1.8
7.4
115
667
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.1
7.4
64
304
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
3.2
7.4
28
88
P28
ICPC
Limited function/disability (P)
3.3
7.4
27
83
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
7.4
121
713
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
7.4
148
921
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.5
7.4
46
190
SPAT1216
SPAT
Assessment of functional ability
1.5
7.3
202
1357
E23.0
ICD-10 Finland
Hypopituitarism
+∞
7.3
7
*
H05AA02
ATC
teriparatide; parenteral
+∞
7.3
7
*
BBA20
NOMESCO Finland
Exploration of parathyroid gland
+∞
7.3
7
*
2535A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Diabetes insipidus
+∞
7.3
7
*
E27.2
ICD-10 Finland
Addisonian crisis
+∞
7.3
7
*
E23.7
ICD-10 Finland
Disorder of pituitary gland, unspecified
+∞
7.3
7
*
E22.8
ICD-10 Finland
Other hyperfunction of pituitary gland
+∞
7.3
7
*
318
Kela drug reimbursment
Teriparatide
+∞
7.3
7
*
D35.30
ICD-10 Finland
Craniopharyngoma
+∞
7.3
7
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
0.7
7.3
371
4807
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.1
7.3
69
340
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.8
7.3
104
589
N91.5
ICD-10 Finland
Oligomenorrhoea, unspecified
4.3
7.2
18
42
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
7.2
137
841
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
7.3
7.2
16
22
N06AX22
ATC
agomelatine; oral
2.1
7.1
62
295
N75
ICPC
Benign neoplasm nervous system
30.1
7.1
9
*
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
3.6
7.1
23
65
A99
ICPC
Disease/condition unspecnature/site
1.6
7.1
188
1249
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
2.7
7.1
38
145
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
7.1
221
1521
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
2.0
7.1
72
363
F25.01
ICD-10 Finland
Schizoaffective syndrome, manic type with prolonged schizophrenic than bipolar symptoms
6.6
7.1
17
26
G44.2
ICD-10 Finland
Tension-type headache
1.4
7.1
291
2118
S97
ICPC
Chronic ulcer skin
1.9
7.0
82
435
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
7.0
547
4410
A01
ICPC
Pain general/multiple sites
1.6
7.0
181
1197
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
4.2
7.0
18
43
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.3
7.0
51
226
SPAT1243
SPAT
Psychiatric/psychological examination
2.0
7.0
71
359
N03AX11
ATC
topiramate; oral
2.1
7.0
63
305
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.9
7.0
32
113
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.8
6.9
106
612
D12
ICPC
Constipation
2.1
6.9
64
312
IFA99, ,
SPAT
5.8
6.9
18
31
SPAT1310
SPAT
Counselling related to known health issue
1.3
6.9
569
4622
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.9
231
1615
ZXY59
NOMESCO Finland
2-person team, nurse-other special worker
7.5
6.9
15
20
E87.8
ICD-10 Finland
Other disorders of electrolyte and fluid balance, not elsewhere classified
13.8
6.9
11
8
S06.3
ICD-10 Finland
Focal brain injury
3.6
6.9
22
62
N06AB10
ATC
escitalopram; oral
1.3
6.8
451
3547
X78
ICD-10 Finland
Intentional self-harm by sharp object
3.5
6.8
23
67
SPAT1301
SPAT
No procedures
1.3
6.8
527
4241
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
2.8
6.8
33
120
D11
ICPC
Diarrhoea
1.4
6.8
266
1918
U02
ICPC
Urinary frequency/urgency
1.4
6.8
277
2014
L04AD02
ATC
tacrolimus; systemic
3.6
6.7
21
58
D01
ICPC
Abdominal pain/cramps general
1.4
6.7
270
1954
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.8
6.7
93
522
F25.1
ICD-10 Finland
Schizoaffective disorder, depressive type
7.2
6.7
15
21
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.0
6.7
29
99
M05BX04
ATC
denosumab; parenteral
2.0
6.7
73
379
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
6.7
344
2603
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
6.7
104
605
A04AA01
ATC
ondansetron; systemic, rectal
1.6
6.6
138
867
IBZ02
NOMESCO Finland
Somatic assessment of psychiatric patient
3.7
6.6
20
54
R60.9
ICD-10 Finland
Oedema, unspecified
1.8
6.6
90
502
E83.50
ICD-10 Finland
Hypercalcemia
4.0
6.6
18
45
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.6
6.6
151
971
NH1AD
NOMESCO Finland
Ankle and foot CT
2.3
6.6
46
200
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
6.6
339
2563
N03AB02
ATC
phenytoin; systemic
3.6
6.6
21
59
183
Kela drug reimbursment
Lamotrigin and topiramate
3.2
6.6
25
79
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.6
1245
11206
P73
ICPC
Affective psychosis
4.2
6.5
17
41
K59.1
ICD-10 Finland
Functional diarrhoea
1.7
6.5
105
617
G44.0
ICD-10 Finland
Cluster headache syndrome
2.8
6.5
31
112
ICZ04
NOMESCO Finland
Preparation of psychiatric treatment plan
5.7
6.4
17
30
S21
ICPC
Skin texture symptom/complaint
1.4
6.4
266
1936
U07
ICPC
Urine symptom/complaint other
1.6
6.4
138
874
P20
ICPC
Memory disturbance
1.6
6.4
139
882
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.9
6.4
28
96
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
70.1
6.4
7
*
A04
ICPC
Weakness/tiredness general
1.4
6.4
314
2355
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
6.4
227
1606
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
6.4
124
766
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.8
6.4
83
457
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.9
6.4
82
450
T28
ICPC
Limited function/disability (T)
3.8
6.4
19
51
Z50.1
ICD-10 Finland
Other physical therapy
1.9
6.4
81
443
Z01.2
ICD-10 Finland
Dental examination
1.3
6.3
977
8566
O92.6
ICD-10 Finland
Galactorrhoea
6.6
6.3
15
23
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.7
6.3
110
660
R5599
NOMESCO Finland
Other rehabilitation service
2.1
6.3
55
263
F25.11
ICD-10 Finland
Schizoaffective syndrome, depressive type with prolonged schizophrenic than bipolar symptoms
6.0
6.3
16
27
F45.0
ICD-10 Finland
Somatization disorder
5.5
6.3
17
31
R04
ICPC
Breathing problem other
1.9
6.3
71
373
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.3
170
1138
V03AE01
ATC
polystyrene sulfonate; oral
3.9
6.3
18
47
BBA50
NOMESCO Finland
Total parathyroidectomy
+∞
6.3
6
*
E23.08
ICD-10 Finland
Hypopituitarism
+∞
6.3
6
*
E34.30
ICD-10 Finland
Short stature NOS
+∞
6.3
6
*
E23.06
ICD-10 Finland
Empty sella
+∞
6.3
6
*
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
+∞
6.3
6
*
E220, D352,
ICD-10 Finland
+∞
6.3
6
*
E34.45
ICD-10 Finland
Abnormal growth increase
+∞
6.3
6
*
25301
ICD-8 Finland
Diseases of pituitary gland, Gigantismus hypophysarius et hyperpituitarismus alius
+∞
6.3
6
*
E21.2
ICD-10 Finland
Other hyperparathyroidism
26.7
6.2
8
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.0
6.2
60
298
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
6.2
195
1346
SPAT1312
SPAT
General health counselling
1.3
6.2
601
4978
R50.9
ICD-10 Finland
Fever, unspecified
1.4
6.2
278
2053
SPAT1167
SPAT
Insertion of urinary catheter
2.5
6.2
36
144
X57
ICD-10 Finland
Unspecified privation
2.3
6.2
43
187
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.2
818
7039
R35
ICD-10 Finland
Polyuria
1.7
6.2
98
573
ZXY82
NOMESCO Finland
Nurse in multidisciplinary team
3.5
6.2
20
57
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
3.5
6.2
20
57
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
6.2
633
5282
B05DA
ATC
Isotonic solutions
5.3
6.1
17
32
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
3.3
6.1
22
67
J01MA14
ATC
moxifloxacin; systemic
1.6
6.1
139
893
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
6.1
208
1459
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
1.8
6.1
92
530
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.6
6.1
126
791
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.7
6.1
114
698
321
Kela drug reimbursment
Paricalcitol and cinacalcet
12.6
6.1
10
8
N06AA09
ATC
amitriptyline; systemic
1.6
6.1
139
895
L29
ICPC
Musculoskeletal sympt/complt other
1.5
6.1
158
1048
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
6.1
374
2908
J01FF01
ATC
clindamycin; systemic
1.3
6.0
455
3642
Z72.8
ICD-10 Finland
Other problems related to lifestyle
3.5
6.0
20
58
XF602
NOMESCO Finland
Bloodpressure monitoring
3.5
6.0
20
58
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
521
97
70.86
307.65
4.0
1.4
20.17
20.80
nmol/l
0.29
511
92
511
656
9.94
307.65
2.1
1.3
7.80
10.43
u/l
3.52
416
513
949
1787
8.80
307.65
4.3
1.8
373.22
382.05
nmol/l
0.72
911
1659
902
1071
13.91
307.65
6.0
1.4
637.41
288.56
mu/l
11.62
873
959
315
313
11.64
286.54
4.9
1.4
699.60
357.41
mu/l
3.92
296
249
271
491
6.18
145.85
1.7
1.3
0.31
0.47
nmol/l
2.46
204
397
409
1064
4.52
145.06
5.2
1.9
9.80
12.41
nmol/l
7.78
384
970
150
166
9.65
124.42
2.4
1.4
275.77
281.17
mosm/kgh2o
1.37
130
127
171
244
7.53
115.09
2.5
1.3
75.09
62.04
mmol/l
2.51
150
208
489
1705
3.43
111.89
2.0
1.3
15.68
25.15
iu/l
10.77
402
1448
170
313
5.82
89.02
3.2
1.6
158.41
204.73
pmol/l
4.44
164
294
361
1315
3.10
74.53
3.0
3.4
4.37
4.59
pmol/l
4.65
337
1190
1210
8040
2.17
65.26
9.8
6.3
1.21
1.21
mmol/l
0.74
1050
6997
1103
7116
2.15
63.62
8.9
5.8
1.22
1.21
mmol/l
1.86
1038
6607
89
123
7.51
61.26
1.6
1.2
5.21
5.65
umol/l
0.41
82
110
1850
15207
2.69
52.39
7.6
4.5
14.71
14.44
pmol/l
4.88
1784
14247
156
422
3.91
50.69
2.0
1.3
13.40
24.20
u/l
6.06
142
354
393
1930
2.27
42.54
7.5
5.8
1.03
1.06
mmol/l
1.23
373
1798
1310
10074
1.78
35.17
7.2
4.6
6.32
6.44
mmol/l
1.42
1242
9358
57
90
6.48
34.66
2.0
1.4
1.90
3.75
nmol/l
0.57
50
65
996
7213
1.72
31.84
5.5
4.6
36.01
36.62
g/l
2.97
930
6802
831
5795
1.71
29.98
3.7
3.2
2.35
2.35
mmol/l
0.27
769
5357
30
26
11.69
29.18
1.8
1.2
5.28
3.93
nmol/l
0.92
30
26
56
104
5.50
28.89
1.4
1.7
—
—
—
0
0
1598
13372
1.79
28.54
9.3
7.4
77.15
75.97
u/l
0.55
1541
12747
227
1041
2.32
28.26
5.0
3.3
85.95
72.53
ng/l
0.80
198
940
1939
17376
2.34
27.43
8.3
5.4
1.68
1.80
mu/l
5.57
1874
16483
77
198
4.00
26.78
2.3
1.9
4.17
4.70
mmol/24h
0.85
70
181
1981
18013
2.50
25.43
24.5
13.8
139.14
139.60
mmol/l
9.32
1950
17656
1590
13462
1.72
25.16
5.0
4.1
11.56
10.22
mm/h
3.63
1519
12731
1092
8422
1.61
25.06
3.2
2.4
75.16
74.79
nmol/l
0.17
1026
7827
1323
10690
1.63
25.05
13.6
9.3
4.15
4.00
e9/l
1.53
1183
9338
428
2580
1.83
24.92
4.4
3.5
0.81
0.82
mmol/l
0.55
408
2447
1980
18058
2.44
24.20
24.3
13.9
3.94
3.93
mmol/l
0.53
1949
17657
237
1177
2.14
24.17
5.2
2.9
1.23
1.23
mmol/l
0.61
213
1004
766
5486
1.62
23.42
3.2
2.5
53.64
58.86
u/l
1.78
711
5114
693
4843
1.64
23.39
3.2
2.1
263.65
175.72
u/l
0.47
666
4637
424
2596
1.79
23.28
3.0
2.3
2.43
2.40
g/l
0.34
387
2423
285
1575
1.94
21.53
9.1
8.7
1.08
0.85
mmol/l
0.45
234
1285
901
6813
1.56
21.28
11.6
10.8
1.14
1.16
inr
0.68
764
5673
58
147
4.03
20.61
10.0
13.6
0.61
0.63
mmol/l
0.28
52
134
283
1592
1.90
20.20
9.4
8.7
5.20
5.08
kpa
1.18
268
1534
283
1593
1.90
20.16
9.4
8.7
13.09
12.91
kpa
0.20
267
1535
377
2330
1.75
19.74
3.1
2.3
21.45
23.46
%
1.97
345
2186
234
1265
1.96
18.77
10.0
7.3
8.05
7.86
mmol/l
0.18
227
1219
35
65
5.46
18.09
1.7
1.2
76.66
68.19
nmol/24h
0.37
35
65
431
2830
1.66
17.88
3.1
2.3
12.93
14.10
umol/l
2.62
401
2654
374
2369
1.70
17.77
1.9
1.6
1218.86
1162.10
nmol/l
0.47
294
1832
627
4514
1.55
17.64
1.8
1.6
20.35
20.30
nmol/l
0.03
546
3929
1097
8891
1.48
17.38
7.2
6.0
10.03
10.68
umol/l
1.52
1042
8469
1206
9973
1.48
17.19
8.7
6.7
0.17
0.19
e9/l
2.77
1069
8859
526
3674
1.57
16.78
3.7
2.5
6.80
7.52
e6/l
0.62
483
3325
642
4690
1.53
16.73
4.3
3.0
0.32
0.37
e6/l
0.35
494
3352
652
4779
1.53
16.73
2.7
2.2
2.61
2.67
mg/l
0.36
559
4177
78
274
2.92
16.72
4.7
2.9
2.21
2.24
mmol/l
0.04
52
169
1194
9894
1.47
16.56
8.5
6.4
1.89
1.96
e9/l
1.97
1072
8859
540
3806
1.56
16.52
3.4
3.0
983.85
1008.09
ng/l
0.06
461
3164
245
1409
1.84
16.18
9.6
9.2
95.45
96.00
%
0.52
234
1366
231
1308
1.86
16.02
5.0
3.5
4.56
4.61
kpa
0.16
226
1270
720
5428
1.49
15.99
4.4
3.0
50.26
81.85
e6/l
0.69
574
4034
911
7199
1.47
15.92
2.3
1.9
99.31
97.51
pmol/l
0.52
489
3917
254
1491
1.80
15.66
5.9
3.9
1.80
1.71
mmol/l
0.19
236
1280
259
1533
1.79
15.53
5.9
3.9
5.88
5.79
kpa
0.97
253
1492
1034
8402
1.45
15.44
15.5
9.9
0.01
0.00
e9/l
0.43
874
6881
74
266
2.85
15.24
7.8
6.3
396.77
372.54
umol/l
0.79
69
235
24
17
14.26
14.53
1.5
1.2
7.10
8.45
pmol/l
0.21
19
17
1794
16361
1.62
14.33
6.5
5.2
38.04
37.94
mmol/mol
0.19
1722
15578
20
9
22.42
14.21
3.5
3.0
197.94
78.68
pmol/l
—
14
9
367
2441
1.61
14.16
2.0
2.3
29.22
29.35
s
0.16
357
2365
1238
10495
1.43
14.14
3.9
3.2
93.85
87.26
ug/l
0.37
1154
9961
226
1326
1.79
13.91
10.8
9.5
121.21
121.38
g/l
0.04
219
1296
167
901
1.93
13.40
4.4
3.3
126.13
131.14
g/l
2.28
162
881
287
1818
1.67
13.40
2.1
1.8
—
—
—
0
0
751
5861
1.44
13.36
4.8
3.1
34.74
53.26
ng/l
0.62
476
3339
1840
16960
1.64
13.20
5.5
4.3
5.74
5.73
mmol/l
0.08
1752
15887
191
1086
1.83
13.03
2.9
2.7
66.21
67.20
g/l
1.02
176
1023
259
1609
1.69
13.00
2.5
2.2
6774.73
6598.83
u/l
0.03
76
648
699
5420
1.43
12.74
3.8
3.5
7.83
7.83
mmol/l
0.00
604
4737
371
2531
1.56
12.74
2.3
1.8
—
—
—
0
0
181
1022
1.84
12.62
5.0
3.4
5.07
5.14
kpa
0.64
174
984
2027
19267
2.16
12.53
25.1
15.4
72.66
70.76
umol/l
1.65
2008
19062
109
516
2.17
12.51
7.2
4.9
1.46
1.29
mg/l
1.37
99
478
438
3113
1.51
12.44
2.7
2.6
2.44
2.43
mmol/l
0.96
385
2786
103
480
2.20
12.29
2.4
2.4
580.87
317.66
ug/l
0.38
96
442
1851
17156
1.62
12.15
18.8
11.7
89.41
89.08
ml/min/173m2
0.27
1729
15603
805
6449
1.40
12.02
3.6
3.2
30.57
29.76
u/l
0.16
762
6144
69
272
2.59
11.95
4.6
2.6
7.00
6.91
pmol/l
0.04
69
272
906
7414
1.39
11.87
2.0
1.8
1.44
1.35
mmol/l
2.22
776
6478
58
211
2.80
11.75
1.3
1.2
362.60
335.05
pmol/l
0.22
53
179
271
1750
1.63
11.67
2.2
1.8
—
—
—
0
0
239
1505
1.66
11.36
4.0
2.8
—
—
—
0
0
198
1193
1.73
11.08
2.9
2.9
72.96
70.81
e9/l
0.35
138
854
1155
9907
1.36
10.94
4.7
3.5
0.01
0.00
estimate
0.64
284
2031
1370
12093
1.37
10.71
6.1
4.2
238.37
2134.14
e6/l
1.94
19
151
74
318
2.37
10.71
1.9
3.0
29.79
32.33
umol/l
0.65
67
292
156
889
1.81
10.57
4.6
3.5
1.54
1.53
mmol/l
0.01
118
651
1167
10061
1.36
10.51
4.8
3.6
0.00
0.16
estimate
0.53
283
1965
1162
10016
1.35
10.45
4.7
3.5
0.00
6.32
estimate
2.31
291
2054
571
4408
1.40
10.24
5.0
3.8
94.45
93.80
%
0.25
564
4310
1941
18355
1.67
9.95
20.2
13.0
20.70
21.42
mg/l
0.48
1636
14859
446
3313
1.44
9.89
1.7
1.6
20419316.37
41218064.13
pmol/l
0.43
382
2858
48
174
2.80
9.83
1.5
1.7
—
—
—
0
0
34
101
3.40
9.73
1.7
1.5
—
—
—
0
0
665
5356
1.35
8.96
1.5
1.4
1.62
1.52
u/ml
0.07
184
1492
114
621
1.88
8.94
1.7
2.1
1.92
4.08
iu/l
7.19
47
266
60
262
2.33
8.44
2.3
1.7
—
—
—
0
0
222
1477
1.56
8.38
2.9
2.8
10.57
10.56
g/l
0.01
194
1373
1477
13400
1.34
8.37
4.2
3.1
44.57
38.65
u/l
1.52
1419
12854
657
5346
1.33
8.10
4.8
3.7
0.00
0.00
estimate
1.54
277
1930
49
199
2.50
8.08
1.6
1.5
—
—
—
0
0
360
2667
1.42
7.96
3.6
2.8
4.45
3.58
e6/l
0.64
194
1240
222
1496
1.54
7.91
2.7
2.3
0.22
0.22
g/l
0.23
200
1405
386
2901
1.40
7.86
3.5
2.7
1.27
1.07
e6/l
0.36
221
1465
23
61
3.80
7.80
2.8
2.4
15.08
15.97
umol/l
0.14
23
61
76
378
2.05
7.78
3.7
3.7
31.72
58.31
mg/l
1.00
62
327
51
216
2.39
7.71
1.7
1.2
0.57
8.79
nmol/l
0.50
51
207
62
286
2.20
7.70
4.9
3.2
1934.00
1535.85
u/ml
—
6
20
48
199
2.44
7.60
1.7
1.5
—
—
—
0
0
26
77
3.41
7.53
1.1
1.5
158.18
150.32
mmol/24h
0.15
26
77
84
439
1.95
7.50
1.3
1.6
182.66
20.86
e6/l
0.48
58
322
176
1140
1.59
7.46
1.9
1.7
—
—
—
0
0
690
5709
1.31
7.42
4.1
2.9
0.00
0.07
estimate
1.12
249
1652
75
378
2.02
7.42
3.7
3.7
28.92
49.31
mg/l
1.16
62
327
154
968
1.64
7.37
6.1
4.1
24.31
24.05
mmol/l
0.62
154
960
571
4605
1.33
7.37
1.6
1.5
2.35
2.21
g/l
0.43
354
2964
81
423
1.95
7.26
1.8
1.6
—
—
—
0
0
84
446
1.92
7.17
1.4
1.6
943.27
1288.04
e6/l
0.12
64
345
254
1799
1.47
7.12
1.3
1.2
110.25
147.41
u/ml
0.87
90
685
79
413
1.95
7.06
2.1
1.5
—
—
—
0
0
135
832
1.66
6.99
1.6
1.5
—
—
—
0
0
15
20
7.55
6.89
1.5
2.2
—
—
—
0
0
45
190
2.40
6.88
1.7
1.2
0.18
0.26
nmol/l
0.36
36
139
531
4296
1.31
6.59
2.6
2.4
320.23
319.89
umol/l
0.02
464
3840
132
822
1.65
6.58
8.2
7.1
25.18
24.36
mmol/l
1.79
122
783
82
447
1.87
6.49
2.5
3.0
2.74
2.35
index
0.12
42
242
40
165
2.45
6.45
6.5
5.0
7.68
6.84
mmol/l
0.38
29
138
25
80
3.15
6.44
1.5
1.8
—
—
—
0
0
70
365
1.95
6.34
9.4
5.6
2751.75
291.38
iu/ml
0.51
12
42
77
416
1.88
6.28
1.6
1.2
—
—
—
0
0
1992
19220
1.59
6.22
14.1
10.5
26.15
25.13
u/l
1.63
1955
18785
880
7648
1.26
6.08
4.7
3.4
0.03
0.03
estimate
0.02
242
1682
98
576
1.74
6.08
1.6
2.0
1.42
1.44
g/l
0.05
82
513
65
336
1.96
6.05
3.4
3.5
8.32
3.33
ratio
0.42
37
194
79
436
1.84
6.04
2.3
1.6
—
—
—
0
0
376
2934
1.34
5.95
4.3
3.4
467.01
360.92
ng/l
0.15
246
1874
345
2661
1.35
5.89
1.9
1.8
1.46
1.41
%
0.63
312
2373
90
522
1.76
5.85
2.4
1.9
7.95
1.82
ug/l
0.47
81
459
378
2963
1.34
5.79
2.0
2.6
89.60
103.32
ug/g
0.78
296
2371
1769
16761
1.33
5.64
4.3
3.8
1.29
1.24
mmol/l
2.82
1680
15817
1701
16035
1.31
5.58
26.1
15.8
13.50
13.40
%
2.98
1685
15836
27
100
2.72
5.43
4.3
3.4
214.00
145.22
umol/l
0.26
16
58
225
1640
1.42
5.40
4.8
4.6
242.44
246.78
u/l
0.14
210
1562
275
2076
1.37
5.37
3.0
2.7
7.97
6.86
umol/l
0.36
219
1796
560
4673
1.27
5.32
4.4
4.1
7.02
9.07
mg/mmol
0.68
351
2957
2065
20177
1.87
5.30
32.7
19.9
265.75
261.13
e9/l
2.52
2040
19857
57
297
1.94
5.23
1.7
1.5
—
—
—
0
0
29
114
2.57
5.21
1.6
1.4
35.86
34.99
%
0.04
22
68
66
362
1.85
5.19
2.7
2.0
130.84
130.95
g/l
0.01
57
293
2065
20184
1.86
5.19
32.6
19.8
90.08
90.39
fl
2.69
2054
20035
18
54
3.35
5.16
1.8
2.7
68.12
84.72
ug/l
0.23
18
54
2065
20187
1.85
5.14
33.4
20.2
39.93
40.48
%
2.23
2054
20028
2065
20188
1.85
5.13
32.6
19.9
4.47
4.50
e12/l
2.84
2036
19826
2065
20191
1.85
5.08
32.8
19.9
6.74
6.73
e9/l
0.08
2036
19819
2065
20197
1.83
4.98
33.0
20.0
133.30
134.90
g/l
6.54
2055
20046
84
505
1.69
4.86
1.5
1.4
241.73
297.64
ug/g
1.72
47
273
123
816
1.54
4.77
3.6
3.0
1.02
1.02
ratio
0.05
111
735
192
1394
1.41
4.73
2.4
2.4
19.31
20.23
au/ml
0.03
14
187
126
843
1.53
4.71
1.6
1.7
—
—
—
0
0
522
4375
1.26
4.70
1.8
1.8
1.26
0.99
mg/l
0.53
411
3303
34
152
2.26
4.67
1.3
1.2
70.10
63.95
u/l
0.16
29
140
35
160
2.21
4.57
1.5
2.2
32.23
32.09
pg
0.05
35
160
162
1151
1.44
4.50
1.7
1.8
1.27
1.40
g/l
0.41
148
1066
79
479
1.67
4.46
1.8
2.4
10.51
10.98
mg/l
0.23
71
457
19
65
2.94
4.44
2.2
1.6
111.73
91.45
ng/l
0.28
19
65
1864
17926
1.33
4.35
5.7
4.9
2.77
2.80
mmol/l
0.99
1788
17032
175
1270
1.41
4.34
2.8
2.2
0.38
0.41
e6/l
0.08
167
1203
1850
17775
1.32
4.33
5.3
4.4
4.65
4.73
mmol/l
3.52
1772
16960
83
516
1.63
4.27
2.7
2.0
3.49
3.67
g/l
0.64
76
486
83
516
1.63
4.27
2.7
2.0
4.22
4.28
g/l
0.30
76
486
83
516
1.63
4.27
2.7
2.0
7.07
7.34
g/l
0.91
75
486
1842
17702
1.31
4.19
5.1
4.4
1.45
1.49
mmol/l
5.37
1763
16805
50
271
1.87
4.15
1.4
1.3
—
—
—
0
0
79
489
1.64
4.14
2.8
2.1
2.82
2.94
g/l
0.53
72
459
24
98
2.47
4.05
1.3
1.1
—
—
—
0
0
58
332
1.77
4.05
1.5
1.3
4.04
3.81
u/ml
0.09
25
150
33
156
2.13
4.00
1.5
1.6
1.14
1.25
promille
0.18
26
125
175
1291
1.39
3.96
1.3
1.3
91.25
38.13
au/ml
—
8
80
48
261
1.86
3.96
1.7
1.4
—
—
—
0
0
91
592
1.56
3.91
6.4
5.6
1.56
1.56
%
0.02
85
557
61
990
0.60
3.73
1.2
1.1
1.52
1.56
g/l
0.50
61
990
132
938
1.43
3.71
3.1
3.0
143.67
164.10
ng/l
0.31
118
841
28
128
2.20
3.70
2.3
2.3
—
—
—
0
0
123
864
1.45
3.68
2.0
1.6
—
—
—
0
0
112
775
1.47
3.62
1.8
2.2
40.73
39.92
u/l
0.18
101
717
63
1005
0.62
3.60
1.2
1.1
0.84
0.87
g/l
0.77
63
1005
515
4424
1.22
3.58
3.0
2.2
—
—
—
0
0
29
137
2.13
3.55
2.5
2.8
442.77
505.24
e6/l
0.40
22
111
42
228
1.86
3.51
5.3
3.3
1.47
1.33
%
0.07
35
211
17
63
2.71
3.49
25.4
33.5
88.58
122.70
ug/l
1.43
12
57
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
62
380
1.65
3.43
3.3
3.9
0.38
0.37
iu/ml
0.05
36
198
15
53
2.84
3.36
4.1
3.9
—
—
—
0
0
51
299
1.72
3.33
1.5
1.7
—
—
—
0
0
21
89
2.37
3.32
1.6
1.6
2.10
1.98
umol/l
0.29
21
79
130
944
1.40
3.27
1.8
1.7
0.16
0.31
mg/l
5.93
54
429
144
1068
1.37
3.20
5.8
2.2
6.08
6.74
ug/l
0.17
123
956
62
388
1.62
3.19
1.7
1.4
—
—
—
0
0
69
444
1.57
3.16
2.8
2.1
9.71
10.43
g/l
0.59
61
413
52
313
1.68
3.11
1.2
1.3
—
—
—
0
0
52
313
1.68
3.11
1.2
1.3
—
—
—
0
0
20
86
2.34
3.08
2.1
1.3
—
—
—
0
0
65
416
1.58
3.06
1.5
1.4
—
—
—
0
0
67
434
1.56
3.00
3.0
2.9
—
—
—
0
0
32
168
1.92
3.00
1.6
1.6
51.68
55.52
%
0.17
19
108
14
51
2.76
2.98
1.1
1.1
116.29
92.51
%
2.40
14
51
62
947
0.64
2.97
1.2
1.1
0.75
0.62
ratio
—
5
93
46
272
1.71
2.95
6.0
8.8
104.07
105.49
mmol/l
0.69
41
245
167
1286
1.32
2.93
1.6
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
21
95
2.22
2.90
1.4
1.2
—
—
—
0
0
77
519
1.50
2.89
1.6
1.3
—
—
—
0
0
6
9
6.68
2.87
1.8
1.3
390.18
422.03
nmol/l
—
6
9
219
2705
0.79
2.84
1.7
1.8
3.52
3.40
ratio
0.67
162
1994
20
90
2.23
2.80
2.1
1.4
—
—
—
0
0
68
450
1.53
2.79
3.7
2.2
0.60
0.83
g/l
0.28
61
403
61
396
1.56
2.74
1.6
1.4
130.86
148.01
au/ml
0.45
14
101
7
14
5.01
2.73
1.3
1.6
35.00
44.38
nmol/l
—
7
14
53
333
1.61
2.73
1.7
1.4
—
—
—
0
0
6
10
6.01
2.70
1.0
1.2
—
—
—
0
0
6
10
6.01
2.70
1.2
2.1
212.67
415.10
ug/l
—
6
10
37
212
1.76
2.67
1.2
1.1
—
—
—
0
0
85
597
1.44
2.63
5.6
4.0
24.60
24.67
mmol/l
0.09
77
568
27
141
1.93
2.60
2.8
2.9
165.09
200.03
e6/l
0.71
22
120
60
395
1.53
2.55
3.0
2.1
0.00
0.00
g/l
0.50
54
365
20
94
2.14
2.55
2.0
1.5
6.47
5.32
u/l
0.18
15
77
12
44
2.74
2.54
1.2
1.1
—
—
—
0
0
6
11
5.47
2.54
6.0
2.2
—
—
—
0
0
41
246
1.68
2.54
1.8
1.4
—
—
—
0
0
228
1865
1.25
2.52
4.6
4.1
31.11
32.23
%
0.81
176
1337
53
343
1.56
2.44
1.2
1.1
—
—
—
0
0
20
96
2.09
2.43
2.1
1.3
—
—
—
0
0
939
8695
1.14
2.43
3.2
2.7
—
—
estimate
—
0
0
5
8
6.26
2.37
3.2
4.9
—
—
—
0
0
22
111
1.99
2.35
2.0
2.0
0.87
2.06
u/field
1.36
16
69
48
307
1.58
2.34
1.8
1.4
—
—
—
0
0
58
388
1.51
2.32
3.2
2.1
0.00
0.00
g/l
-0.00
51
344
211
1729
1.24
2.31
3.4
2.4
30.85
67.57
u/l
0.72
182
1458
30
170
1.78
2.29
1.1
1.1
—
—
—
0
0
166
1325
1.27
2.28
3.1
2.3
75.70
75.67
ml/min/173m2
0.00
66
519
16
72
2.23
2.27
1.4
1.3
123.61
172.03
pmol/l
0.98
16
72
6
13
4.63
2.27
2.5
4.2
—
—
—
0
0
424
3721
1.17
2.27
2.4
2.2
—
—
—
0
0
9
29
3.11
2.22
1.4
1.2
—
—
—
0
0
12
48
2.51
2.18
1.5
1.1
—
—
—
0
0
51
338
1.52
2.15
1.5
1.3
2.33
4.35
u/ml
1.11
21
124
7
19
3.69
2.15
1.9
1.2
—
—
—
0
0
30
174
1.73
2.13
2.2
2.1
20.00
22.37
mg/l
—
10
71
416
3664
1.17
2.12
1.4
1.3
5.35
9.74
u/ml
1.30
162
1529
459
4079
1.16
2.09
2.5
2.3
—
—
—
0
0
36
568
0.63
2.08
1.3
1.3
—
—
—
0
0
33
199
1.67
2.05
1.9
2.0
—
—
—
0
0
11
44
2.51
2.01
1.4
1.1
—
—
—
0
0
12
51
2.36
1.95
1.6
1.1
—
—
—
0
0
12
51
2.36
1.95
1.5
1.1
—
—
—
0
0
12
51
2.36
1.95
1.5
1.1
—
—
—
0
0
492
4416
1.15
1.95
4.6
3.6
1.02
1.71
kg/l
0.80
330
2929
14
64
2.20
1.94
4.6
3.6
0.93
1.17
%
0.24
14
64
204
1701
1.22
1.93
8.1
5.5
—
—
—
0
0
12
52
2.32
1.87
1.4
1.3
—
—
—
0
0
111
868
1.29
1.84
1.3
1.3
0.20
1.13
u/ml
—
8
64
6
17
3.54
1.84
1.5
1.1
—
—
—
0
0
5
12
4.17
1.82
10.6
9.2
4.36
6.11
mmol/l
—
5
12
172
2071
0.82
1.82
1.5
1.6
3.47
3.46
mmol/l
0.03
120
1381
320
2796
1.17
1.82
5.4
4.9
1.49
2.21
ug/l
3.26
296
2525
15
73
2.06
1.80
3.5
1.8
—
—
—
0
0
15
73
2.06
1.80
3.5
1.8
—
—
—
0
0
15
73
2.06
1.80
1.3
1.3
—
—
—
0
0
15
73
2.06
1.80
3.5
1.8
—
—
—
0
0
15
73
2.06
1.80
3.5
1.8
—
—
—
0
0
22
123
1.80
1.80
1.4
1.6
—
—
—
0
0
7
23
3.05
1.80
1.6
1.7
—
—
—
0
0
11
47
2.35
1.77
1.1
1.5
—
—
—
0
0
170
2042
0.82
1.76
1.5
1.6
886.46
1015.59
mu/l
1.15
152
1717
6
19
3.16
1.66
2.2
1.3
—
—
—
0
0
102
803
1.28
1.63
1.4
1.4
—
—
—
0
0
38
253
1.51
1.63
1.1
1.2
18.51
40.04
u/l
1.20
32
219
107
1328
0.80
1.53
1.4
1.4
—
—
—
0
0
5
15
3.34
1.52
1.6
1.1
—
—
—
0
0
6
21
2.86
1.50
2.3
1.6
—
—
—
0
0
11
51
2.16
1.50
2.1
1.9
40.89
41.53
g/l
0.12
11
51
15
269
0.55
1.49
1.4
1.5
—
—
—
0
0
22
131
1.69
1.49
3.2
2.7
—
—
—
0
0
12
58
2.08
1.49
3.8
3.5
1.79
1.94
ratio
0.17
12
51
23
139
1.66
1.48
3.0
1.6
—
—
—
0
0
23
139
1.66
1.48
3.0
1.6
—
—
—
0
0
23
139
1.66
1.48
3.0
1.6
—
—
—
0
0
9
37
2.44
1.48
2.9
2.3
0.54
0.61
mmol/l
—
9
37
24
147
1.64
1.47
1.5
1.6
—
—
—
0
0
26
163
1.60
1.46
1.1
1.1
—
—
—
0
0
66
498
1.34
1.46
1.3
1.3
—
38.32
—
0
13
9
38
2.37
1.45
1.2
1.2
—
—
—
0
0
32
212
1.52
1.43
1.8
1.5
—
—
—
0
0
32
213
1.51
1.41
1.8
1.5
—
—
—
0
0
6
23
2.61
1.36
1.5
1.0
—
—
—
0
0
22
135
1.64
1.36
1.1
1.4
—
—
—
0
0
438
3994
1.12
1.35
1.4
1.3
34.59
25.78
iu/ml
0.48
122
1175
23
143
1.62
1.35
1.2
1.3
—
—
—
0
0
24
151
1.60
1.35
1.3
1.2
0.50
0.60
ratio
2.36
12
88
31
210
1.48
1.28
1.9
1.5
—
—
—
0
0
22
139
1.59
1.23
1.2
1.1
1.47
1.03
u/l
0.55
11
64
181
1565
1.17
1.23
1.4
1.3
589.74
224.40
u/ml
0.37
166
1455
5
19
2.64
1.21
2.2
1.2
—
—
—
0
0
61
471
1.30
1.19
1.4
1.3
276.94
243.66
u/ml
0.39
41
288
6
26
2.31
1.18
1.0
1.3
—
—
—
0
0
1469
14272
1.10
1.16
3.9
3.6
—
—
—
0
0
123
1034
1.20
1.16
1.3
1.3
248.09
227.84
miu/ml
0.22
53
535
22
142
1.56
1.14
1.2
1.3
—
—
—
0
0
8
40
2.00
1.12
1.3
1.1
—
—
—
0
0
76
610
1.26
1.12
1.4
1.3
12.35
10.25
u/ml
—
10
98
96
1157
0.82
1.10
1.4
1.5
61.18
60.31
ug/l
0.06
87
971
52
398
1.31
1.10
1.5
1.7
21852.33
11420.95
e6/l
0.61
36
279
14
81
1.73
1.09
1.1
1.2
144.64
377.18
u/l
0.95
14
72
156
1349
1.17
1.08
1.1
1.1
—
—
—
0
0
29
202
1.44
1.07
1.9
1.5
—
—
—
0
0
29
203
1.43
1.05
1.9
1.5
—
—
—
0
0
12
67
1.80
1.04
1.1
1.0
—
—
—
0
0
29
204
1.43
1.03
1.9
1.5
—
—
—
0
0
28
196
1.43
1.02
1.3
1.2
0.07
2.52
u/ml
2.94
16
97
9
47
1.92
1.02
1.7
1.1
—
—
—
0
0
49
377
1.31
1.02
3.5
2.6
0.78
0.85
nmol/l
0.24
44
324
90
1078
0.83
0.99
1.4
1.5
0.89
0.95
ratio
1.19
57
646
90
1078
0.83
0.99
1.4
1.5
1.11
1.21
ratio
0.54
57
650
89
1066
0.83
0.98
1.4
1.5
—
—
—
0
0
23
156
1.48
0.98
1.0
1.1
113.52
109.65
pmol/l
0.14
23
156
90
1076
0.83
0.98
1.4
1.5
1.04
1.16
ratio
0.75
57
644
105
887
1.19
0.97
1.8
2.0
8.57
7.82
iu/ml
0.06
17
214
10
54
1.86
0.96
4.5
2.0
—
—
—
0
0
10
54
1.86
0.96
4.5
2.0
—
—
—
0
0
10
54
1.86
0.96
4.5
2.0
—
—
—
0
0
42
546
0.76
0.95
1.4
1.4
59.89
137.73
pmol/l
1.73
42
531
0
32
0.00
0.95
0.0
1.1
—
5.28
—
0
24
11
62
1.78
0.94
1.4
1.3
—
—
—
0
0
19
125
1.52
0.94
1.3
1.6
0.52
0.49
e9/l
0.13
19
125
12
70
1.72
0.92
1.2
1.2
13.50
13.06
u/l
0.06
12
64
29
210
1.39
0.90
1.2
1.1
—
—
—
0
0
5
102
0.49
0.89
1.2
2.9
20.74
99.16
ug/l
—
5
88
83
694
1.20
0.88
1.6
1.5
0.14
0.15
iu/ml
0.00
13
111
6
30
2.00
0.87
1.5
1.8
1.22
1.21
mmol/l
—
6
30
25
179
1.40
0.84
1.6
1.6
—
—
—
0
0
66
543
1.22
0.83
2.3
1.8
—
—
—
0
0
41
319
1.29
0.82
2.9
2.5
52.69
110.58
ug/min
1.12
23
203
13
81
1.61
0.81
1.3
2.7
6.89
8.32
mmol/l
1.45
13
81
63
761
0.82
0.80
1.4
1.5
59.42
61.12
ug/l
0.12
63
761
23
164
1.41
0.80
3.6
1.7
—
—
—
0
0
16
106
1.51
0.79
1.6
1.2
—
—
—
0
0
24
173
1.39
0.78
2.7
3.3
0.83
0.87
nmol/l
0.15
18
145
14
90
1.56
0.78
1.3
1.6
28.93
29.26
umol/l
0.03
14
80
83
974
0.85
0.77
1.4
1.5
—
—
—
0
0
24
174
1.38
0.76
1.2
1.1
—
—
—
0
0
73
865
0.84
0.76
1.7
1.8
—
—
—
0
0
6
34
1.77
0.76
1.2
1.4
—
—
—
0
0
25
183
1.37
0.76
3.4
1.7
—
—
—
0
0
9
58
1.55
0.69
1.1
1.1
—
—
—
0
0
71
602
1.19
0.69
2.7
1.9
—
—
—
0
0
19
135
1.41
0.69
1.0
1.1
3.12
4.43
nmol/l
—
5
19
12
77
1.56
0.68
1.1
2.1
—
—
—
0
0
12
77
1.56
0.68
1.1
2.1
—
—
—
0
0
7
42
1.67
0.68
1.0
1.1
—
—
—
0
0
11
69
1.60
0.68
1.2
1.2
—
—
—
0
0
85
981
0.86
0.67
1.5
1.6
—
—
—
0
0
46
375
1.23
0.66
1.1
1.1
—
—
—
0
0
11
70
1.57
0.65
2.5
1.4
—
—
—
0
0
17
120
1.42
0.64
1.2
1.3
5.20
6.18
mmol/l
1.08
17
110
34
269
1.27
0.64
1.4
1.2
—
—
—
0
0
241
2231
1.09
0.61
4.1
4.1
23.77
21.20
%
1.42
101
953
5
30
1.67
0.61
1.6
3.5
3.60
5.70
ug/l
—
5
30
75
648
1.16
0.60
1.1
1.1
6.20
4.79
eliau/ml
—
7
101
13
88
1.48
0.60
1.2
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
2.0
—
7.43
—
0
11
8
52
1.54
0.59
3.0
1.4
—
—
—
0
0
8
52
1.54
0.59
3.0
1.4
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
8
53
1.51
0.58
1.0
1.2
—
67.27
—
0
15
8
55
1.46
0.56
1.0
1.2
—
—
—
0
0
6
37
1.62
0.55
1.5
2.7
5.03
4.61
kpa
—
6
37
6
37
1.62
0.55
1.5
2.7
8.68
10.73
kpa
—
6
37
15
107
1.40
0.55
3.1
3.6
0.87
0.81
index
0.12
15
107
57
494
1.16
0.47
1.8
1.6
—
—
—
0
0
10
68
1.47
0.47
2.6
1.4
—
—
—
0
0
33
395
0.83
0.45
1.5
1.9
—
—
—
0
0
130
1196
1.09
0.42
2.2
2.8
22.20
57.66
u/ml
2.54
125
1153
7
106
0.66
0.39
1.1
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
2.3
—
3.10
—
0
19
33
279
1.19
0.38
2.7
2.6
18.56
34.02
iu/ml
—
5
16
11
81
1.36
0.36
1.0
1.1
—
—
—
0
0
16
126
1.27
0.35
1.0
1.1
1465.25
1542.64
miu/ml
0.12
16
126
77
846
0.91
0.34
1.7
1.9
—
—
—
0
0
18
146
1.23
0.32
1.6
1.3
—
—
—
0
0
23
192
1.20
0.32
3.6
4.7
21.39
87.30
u/ml
—
8
58
15
119
1.26
0.31
1.3
1.3
73.33
73.55
umol/l
0.01
15
119
13
101
1.29
0.31
1.7
1.2
—
—
—
0
0
40
352
1.14
0.31
3.0
3.5
22.37
23.98
mg/l
0.15
27
239
13
103
1.26
0.28
5.0
7.3
6.41
187.44
ug/l
—
7
65
51
564
0.90
0.28
1.1
1.1
1.56
1.71
u/ml
0.06
25
284
8
65
1.23
0.27
1.8
1.5
8.46
8.33
ug/l
—
8
65
177
1685
1.06
0.26
3.0
3.0
0.62
0.73
ug/l
1.77
117
977
148
1404
1.06
0.25
4.1
4.2
69.34
23.47
ug/l
0.38
117
1097
59
543
1.09
0.23
1.3
1.1
—
—
—
0
0
13
107
1.22
0.21
2.1
1.7
—
814799.86
—
0
7
459
4485
1.03
0.21
1.6
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
21
182
1.16
0.21
1.4
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
61
567
1.08
0.20
1.1
1.1
1.70
1.29
u/ml
0.13
25
260
6
50
1.20
0.19
1.2
1.1
—
—
—
0
0
534
5237
1.03
0.19
1.9
1.7
—
—
—
0
0
63
588
1.07
0.19
1.1
1.1
4.37
6.30
u/ml
0.33
28
335
6
53
1.13
0.18
1.7
1.5
—
—
—
0
0
42
454
0.92
0.17
1.1
1.1
3.65
5.65
u/ml
0.39
14
201
7
88
0.79
0.14
1.0
1.1
120.21
164.30
iu/ml
—
7
88
95
910
1.05
0.14
1.5
1.7
3.64
4.44
mg/l
0.40
71
652
46
488
0.94
0.12
1.1
1.1
0.90
4.28
u/ml
4.58
18
246
19
210
0.90
0.12
1.1
1.2
12.02
15.85
u/ml
—
6
99
40
426
0.94
0.12
1.1
1.1
0.05
0.26
u/ml
1.86
12
132
57
542
1.05
0.11
1.3
1.1
—
—
—
0
0
43
455
0.94
0.11
1.1
1.1
16.83
14.29
au/ml
—
6
129
45
426
1.06
0.10
1.5
1.2
—
—
—
0
0
11
124
0.89
0.09
1.1
1.2
—
—
—
0
0
100
1027
0.97
0.08
1.5
1.5
—
—
—
0
0
6
70
0.86
0.07
2.0
1.2
77.80
97.52
nmol/l
—
6
53
6
70
0.86
0.07
1.2
1.1
—
—
—
0
0
68
658
1.03
0.07
1.2
1.1
0.35
2.52
u/ml
7.13
34
361
273
2765
0.99
0.07
2.3
2.1
—
—
—
0
0
12
132
0.91
0.06
4.0
3.7
—
—
—
0
0
42
404
1.04
0.06
1.2
1.3
—
—
—
0
0
17
158
1.08
0.06
1.0
1.2
—
290.00
—
0
5
74
759
0.97
0.06
1.2
1.3
—
—
—
0
0
39
377
1.04
0.04
1.1
1.1
1.97
2.15
eliau/ml
0.10
19
193
50
488
1.03
0.03
2.5
2.3
4.86
4.74
umol/l
0.06
36
359
18
189
0.95
0.03
1.1
1.1
9.53
7.82
iu/ml
—
7
58
80
812
0.98
0.03
1.5
1.6
11.63
10.69
u/ml
0.05
14
208
18
188
0.96
0.02
1.3
1.1
—
—
—
0
0
122
1228
0.99
0.01
1.4
1.4
—
—
—
0
0
18
175
1.03
0.00
1.3
1.1
—
—
—
0
0
21
211
1.00
0.00
1.3
1.2
—
—
—
0
0
50
499
1.00
0.00
3.7
3.6
312.26
2999.83
u/ml
0.76
42
438
11
114
0.96
0.00
1.3
1.1
—
—
—
0
0
18
184
0.98
0.00
1.3
1.1
—
—
—
0
0
23
226
1.02
0.00
1.4
1.2
—
—
—
0
0
13
128
1.02
0.00
1.3
1.2
21.54
7.85
mm/h
1.00
13
128
15
152
0.99
0.00
1.0
1.2
—
—
—
0
0
230
2303
1.00
0.00
2.0
2.0
—
—
—
0
0
18
183
0.98
0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
18
180
1.00
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
34.54
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
26.64
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
20.28
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.76
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
2.7
2.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_HYPERPIT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_HYPERPIT | 1.864 [1.59, 2.18] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.314 |
During the follow-up period (1.1.1998 — 31.12.2019), 660 out of 7880 females with E4_HYPERPIT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_HYPERPIT | 1.915 [1.63, 2.25] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.036 |
During the follow-up period (1.1.1998 — 31.12.2019), 521 out of 2276 males with E4_HYPERPIT died.
Mortality risk
Mortality risk for people of age
years, who have E4_HYPERPIT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.217% | 0.38% |
| 5 | 1.083% | 2.337% |
| 10 | 2.632% | 6.055% |
| 15 | 5.096% | 10.909% |
| 20 | 9.329% | 18.171% |
Relationships between endpoints
↥Index endpoint: E4_HYPERPIT – Hyperfunction of pituitary gland
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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