Keratitis and keratoconjunctivitis in other diseases classified elsewhere

H7_KERATITISINOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1618

4. Check minimum number of events

None

1618

5. Include endpoints

None

1618

6. Filter based on genotype QC (FinnGen only)

1431

Control definitions (FinnGen only)

Control exclude
H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9965 6270 3655
Only index persons 9295 5917 3378
Unadjusted period prevalence (%)
Whole population 0.15 0.18 0.10
Only index persons 0.19 0.22 0.13
Median age at first event (years)
Whole population 57.25 57.87 56.25
Only index persons 56.48 57.07 55.45

-FinnGen-

Key figures

All Female Male
Number of individuals 1431 935 496
Unadjusted period prevalence (%) 0.30 0.33 0.23
Median age at first event (years) 58.92 56.42 63.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1492
Matched controls
14920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
750.4
307.7
391
7
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
2542.5
307.7
606
*
S01AD03
ATC
aciclovir; ophthalmic
37.2
307.7
448
170
B02.3
ICD-10 Finland
Zoster ocular disease
135.8
292.6
147
12
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
18.4
254.1
212
133
H19.2*B30.0
ICD-10 Finland
Epidemic keratoconjunctivitis
+∞
233.6
218
*
H16.0
ICD-10 Finland
Corneal ulcer
20.1
217.4
172
96
H04.10
ICD-10 Finland
Dry eye syndrome
6.2
209.9
452
977
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
5.7
209.3
1104
4982
J05AB11
ATC
valaciclovir; oral
5.5
201.8
530
1364
H19.3
ICD-10 Finland
Keratitis and keratoconjunctivitis in other diseases classified elsewhere
975.8
180.2
173
*
J05AB01
ATC
aciclovir; systemic
4.2
153.2
627
2214
H19.2
ICD-10 Finland
Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
1485.7
141.0
135
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
180.8
127.7
132
8
S01XA18
ATC
ciclosporin; ophthalmic
25.5
126.2
89
37
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
1255.6
120.6
116
*
H16.9
ICD-10 Finland
Keratitis, unspecified
167.4
118.2
123
8
B02.9
ICD-10 Finland
Zoster without complication
4.7
93.6
243
591
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.0
93.2
310
910
H22.0*B02.3
ICD-10 Finland
Zoster iridocyclitis
+∞
89.5
85
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.9
89.4
736
3726
P01BA02
ATC
hydroxychloroquine; oral
4.4
88.6
256
676
H03.1*B02.3
ICD-10 Finland
Zoster blepharitis
29.5
80.8
54
19
H16.2
ICD-10 Finland
Keratoconjunctivitis
369.3
71.3
71
*
B02.8
ICD-10 Finland
Zoster with other complications
14.2
60.7
56
41
H57.1
ICD-10 Finland
Ocular pain
5.7
60.3
117
219
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.8
60.0
387
1663
S01GX01
ATC
cromoglicic acid; ophthalmic
2.7
58.6
417
1881
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.9
55.3
177
497
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.1
49.9
241
877
H15.1
ICD-10 Finland
Episcleritis
20.5
49.6
38
19
L04AX01
ATC
azathioprine; systemic
4.8
49.5
117
260
L04AX03
ATC
methotrexate; systemic
3.2
47.7
216
756
H02AB06
ATC
prednisolone; systemic
2.1
43.9
824
5473
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
64.6
43.4
50
8
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
11.6
41.5
43
38
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.5
41.1
155
483
H01.0
ICD-10 Finland
Blepharitis
3.4
41.1
163
525
G53.0
ICD-10 Finland
Postzoster neuralgia
12.4
40.3
40
33
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
397.6
39.2
39
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
8.3
39.0
52
65
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.3
36.8
150
490
S01BA01
ATC
dexamethasone; ophthalmic
4.7
36.8
87
193
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
36.6
35
*
L01BA01
ATC
methotrexate; systemic
4.3
35.3
93
225
CG2S4
NOMESCO Finland
Photography of cornea
66.6
34.1
39
6
L04AA01
ATC
[U] ciclosporin
8.4
33.5
44
54
B02
ICD-10 Finland
Zoster [herpes zoster]
3.4
32.7
122
377
S01BC03
ATC
diclofenac; ophthalmic
5.3
31.1
63
122
S01GX05
ATC
lodoxamide; ophthalmic
7.3
31.1
46
65
N03AX16
ATC
[U] pregabalin
2.0
29.7
408
2341
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.2
29.7
125
416
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.9
29.2
143
519
L88
ICPC
Rheumatoid/seropositive arthritis
3.7
28.0
93
266
G53.0*B02.20
ICD-10 Finland
Trigeminal neuralgia after shingles
29.1
27.7
37
13
S01BA04
ATC
prednisolone; ophthalmic
5.6
27.5
53
98
B00.5
ICD-10 Finland
Herpesviral ocular disease
38.6
27.2
34
9
H10.5
ICD-10 Finland
Blepharoconjunctivitis
5.1
26.4
56
113
S01ED51
ATC
timolol, combinations; ophthalmic
2.7
26.4
155
618
S01BA07
ATC
fluorometholone; ophthalmic
6.4
26.3
44
71
H10.4
ICD-10 Finland
Chronic conjunctivitis
7.1
25.9
39
56
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
25.9
604
4082
S01ED01
ATC
timolol; ophthalmic
3.8
25.2
79
217
S01EC01
ATC
acetazolamide; systemic
5.1
24.5
52
105
S01AA01
ATC
chloramphenicol; ophthalmic
3.1
24.4
104
348
L04AB01
ATC
etanercept; parenteral
6.3
24.2
41
67
S01FA04
ATC
cyclopentolate; ophthalmic
9.8
24.2
28
29
N03AX12
ATC
[U] gabapentin; oral
2.0
24.0
290
1574
H13.1*B02.3
ICD-10 Finland
Zoster conjunctivitis
243.8
23.7
24
*
F29
ICPC
Eye symptom/complaint other
2.3
23.7
194
903
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
4.4
23.4
60
142
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.0
22.8
106
373
J01DB01
ATC
cefalexin; oral
2.0
22.8
1244
10624
S01AX11
ATC
[U] ofloxacin
3.5
22.7
80
238
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
4.2
22.6
61
150
A07EC01
ATC
sulfasalazine; oral, rectal
2.6
22.4
141
582
L04AA06
ATC
mycophenolic acid; systemic
5.1
22.2
47
95
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
9.1
22.1
27
30
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.4
22.1
80
242
S01KA02
ATC
hypromellose; ophthalmic
4.6
22.1
53
119
S01GX09
ATC
olopatadine; ophthalmic
3.9
21.8
65
172
H02AB04
ATC
methylprednisolone; systemic
2.1
21.8
251
1336
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.3
21.7
56
133
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
21.7
758
5651
H17.8
ICD-10 Finland
Other corneal scars and opacities
223.1
21.6
22
*
N02AX02
ATC
tramadol; systemic, rectal
1.7
21.6
672
4852
S70
ICPC
Herpes zoster
3.7
21.4
70
198
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
21.1
175
818
286
Kela drug reimbursment
Ciclosporin eye drop
60.9
20.9
24
*
H17.1
ICD-10 Finland
Other central corneal opacity
+∞
20.9
20
*
A07AA02
ATC
nystatin; oral
2.7
20.8
115
444
R51.80
ICD-10 Finland
Headache
2.0
20.7
265
1462
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.5
20.4
133
557
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
20.3
254
1389
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.1
20.3
87
292
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.4
19.9
74
228
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.5
19.7
136
585
F01
ICPC
Eye pain
3.7
19.4
61
168
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
19.3
183
902
CG2T4
NOMESCO Finland
Topography assessment of cornea
18.5
19.1
29
16
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
19.1
374
2360
L04AA13
ATC
[U] leflunomide
4.0
19.1
54
138
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
8.2
18.8
25
31
R06.0
ICD-10 Finland
Dyspnoea
1.7
18.8
453
3029
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
18.7
551
3884
S01EA05
ATC
brimonidine; ophthalmic
3.9
18.6
55
145
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
3.8
18.2
56
152
R06AE07
ATC
cetirizine; oral
1.6
18.1
659
4886
J01MA02
ATC
ciprofloxacin; systemic
1.6
18.1
595
4304
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
7.0
17.8
27
39
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
27.1
17.8
24
9
CCC00
NOMESCO Finland
Occlusion of lacrimal punctum or canaliculus
+∞
17.7
17
*
H22.0*B00.5
ICD-10 Finland
Herpesviral iridocyclitis
+∞
17.7
17
*
H16.8
ICD-10 Finland
Other keratitis
96.2
17.6
19
*
E0000UV, ,
ATC
1.6
17.4
633
4678
N02BF02
ATC
pregabalin; oral
2.4
17.3
126
555
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
21.2
17.3
25
12
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
21.2
17.3
25
12
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
17.3
329
2050
H02AB07
ATC
prednisone; oral
1.9
17.0
228
1273
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
50.6
17.0
20
*
B30.0
ICD-10 Finland
Keratoconjunctivitis due to adenovirus
+∞
16.7
16
*
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
+∞
16.7
16
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
16.7
165
826
M45
ICD-10 Finland
Ankylosing spondylitis
4.8
16.6
37
78
ZXA05
NOMESCO Finland
Left side
1.7
16.4
385
2539
B00.10
ICD-10 Finland
Herpes simplex facialis
6.2
16.4
28
46
G73.7*M35.0
ICD-10 Finland
Myopathy in sicca syndrome [Sjögren]
40.6
16.3
20
5
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
16.2
564
4107
M79.7
ICD-10 Finland
Fibromyalgia
3.0
16.0
72
249
ZXE00
NOMESCO Finland
One hour or less
1.6
15.6
571
4197
A02BC01
ATC
omeprazole; systemic
1.6
15.6
417
2841
XX9XE
NOMESCO Finland
Other ultrasound examination
6.3
15.5
26
42
S01GX08
ATC
ketotifen; ophthalmic
2.7
15.5
85
327
N06AX11
ATC
mirtazapine; oral
1.6
15.4
521
3758
N06AX21
ATC
duloxetine; oral
1.9
15.3
200
1106
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
15.2
455
3185
M01CB03
ATC
auranofin; oral
6.3
15.0
25
40
A02BC02
ATC
pantoprazole; systemic
1.6
14.9
1023
8628
A02BC05
ATC
esomeprazole; systemic
1.6
14.9
610
4587
XCK00
NOMESCO Finland
Perimetry
2.4
14.8
105
457
R4110
NOMESCO Finland
Physiotherapy
1.6
14.8
426
2949
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
3.7
14.8
46
126
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
4.9
14.8
32
66
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.1
14.8
40
99
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
14.7
154
786
L04AD01
ATC
ciclosporin; systemic
4.3
14.6
38
91
H20.8
ICD-10 Finland
Other iridocyclitis
80.9
14.6
16
*
H13.1*B30.1
ICD-10 Finland
Conjunctivitis due to adenovirus
80.9
14.6
16
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.2
14.5
57
182
H10
ICD-10 Finland
Conjunctivitis
2.3
14.5
116
533
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
14.4
136
668
ZXA00
NOMESCO Finland
Right side
1.6
14.3
404
2781
J01AA02
ATC
doxycycline; systemic
1.6
14.1
1146
9982
N02BE01
ATC
paracetamol; systemic, rectal
1.9
14.1
1335
12137
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
14.1
399
2747
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
14.0
185
1024
TGC00
NOMESCO Finland
Bronchial lavation
3.4
14.0
51
155
TEA00
NOMESCO Finland
Biopsy of lip
5.3
13.9
28
54
H03.1
ICD-10 Finland
Involvement of eyelid in other infectious diseases classified elsewhere
30.3
13.9
18
6
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.0
13.9
154
803
Z3231
NOMESCO Finland
Registered nurse
1.6
13.7
400
2769
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
13.7
509
3730
L17
ICPC
Foot/toe symptom/complaint
1.6
13.6
467
3358
M01CB01
ATC
sodium aurothiomalate; parenteral
4.6
13.6
32
71
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
13.5
271
1704
H10.2
ICD-10 Finland
Other acute conjunctivitis
4.2
13.5
35
84
S29
ICPC
Skin symptom/complaint other
1.7
13.5
316
2072
XCH00
NOMESCO Finland
Eye pressure measurement
2.5
13.4
85
351
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
13.4
301
1951
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.8
13.3
207
1207
J01FF01
ATC
clindamycin; systemic
1.6
13.3
397
2760
H18.8
ICD-10 Finland
Other specified disorders of cornea
40.4
13.2
16
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
13.1
208
1220
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
13.1
301
1961
127
Kela drug reimbursment
Transplant complication
4.6
13.1
31
69
F03
ICPC
Eye discharge
2.2
13.1
111
522
J01FA10
ATC
azithromycin; systemic
1.5
13.0
803
6524
ZXA10
NOMESCO Finland
Bilateral
1.7
13.0
278
1777
A02BC03
ATC
lansoprazole; oral
1.6
13.0
432
3079
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
12.9
526
3920
G53.0*B02.21
ICD-10 Finland
Postherpetic geniculate ganglionitis
22.8
12.9
18
8
XCK10
NOMESCO Finland
Photography of fundus of eye
2.0
12.9
147
774
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.9
12.9
62
223
H18.4
ICD-10 Finland
Corneal degeneration
50.5
12.9
15
*
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
12.8
115
553
H03AA01
ATC
levothyroxine sodium; systemic
1.6
12.8
370
2550
A01AB09
ATC
miconazole; local oral
2.0
12.7
144
756
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
12.7
244
1515
SBA10
NOMESCO Finland
Measurement of salivary flow rate
4.7
12.6
29
63
J01FA06
ATC
roxithromycin; oral
1.5
12.5
585
4481
R03AC02
ATC
salbutamol; inhalant
1.5
12.5
799
6519
R01AD09
ATC
mometasone; nasal
1.5
12.4
651
5101
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
12.4
180
1028
M01AH01
ATC
celecoxib; oral
1.7
12.3
275
1775
M05BA04
ATC
alendronic acid; oral
1.9
12.3
161
888
S01GX04
ATC
nedocromil; ophthalmic
3.9
12.2
36
95
Z71.8
ICD-10 Finland
Other specified counselling
1.5
12.2
490
3633
Z2221
NOMESCO Finland
Medical doctor
1.6
12.1
399
2829
M79.6
ICD-10 Finland
Pain in limb
1.5
12.1
656
5166
J01MA12
ATC
levofloxacin; systemic
1.7
11.9
279
1824
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.8
11.9
59
216
R05
ICD-10 Finland
Cough
1.6
11.8
318
2151
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
11.7
159
887
R50.9
ICD-10 Finland
Fever, unspecified
1.7
11.7
224
1388
R52.9
ICD-10 Finland
Pain, unspecified
1.9
11.6
162
912
N02BF01
ATC
gabapentin; oral
1.8
11.6
174
1002
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
11.6
673
5358
H15.0
ICD-10 Finland
Scleritis
+∞
11.5
11
*
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
11.5
11
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
11.4
407
2935
Z3226
NOMESCO Finland
Physiotherapist
1.6
11.3
269
1762
M54.5
ICD-10 Finland
Low back pain
1.5
11.3
530
4041
H02AB09
ATC
hydrocortisone; systemic
3.3
11.3
43
135
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.8
11.2
55
200
J02AC01
ATC
fluconazole; systemic
1.5
11.2
562
4341
R06AX27
ATC
desloratadine; oral
1.5
11.1
395
2844
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
11.0
574
4463
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
10.9
411
2990
H13.1
ICD-10 Finland
Conjunctivitis in infectious and parasitic diseases classified elsewhere
43.6
10.9
13
*
E000001, ,
ATC
1.6
10.8
275
1833
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
10.8
374
2675
N06AX16
ATC
venlafaxine; oral
1.7
10.7
208
1291
A01
ICPC
Pain general/multiple sites
1.8
10.6
166
968
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
4.0
10.5
29
73
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
10.4
116
605
J01DA01
ATC
[U] cefalexin
1.4
10.4
883
7488
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
10.3
213
1344
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
10.3
620
4937
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
23.5
10.2
14
6
R03DC03
ATC
montelukast; oral
1.6
10.2
245
1606
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.5
10.2
66
276
E000002, ,
ATC
1.8
10.1
150
860
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
10.0
418
3102
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.3
9.9
74
330
G44.2
ICD-10 Finland
Tension-type headache
1.7
9.9
202
1269
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
9.9
115
609
S01EX03, ,
ATC
3.2
9.9
38
120
L04AB04
ATC
adalimumab; parenteral
3.3
9.9
36
110
L04AA11
ATC
[U] etanercept
12.3
9.9
17
14
J01EA01
ATC
trimethoprim; systemic
1.5
9.8
391
2868
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
9.8
326
2306
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.7
718
5907
S01EE01
ATC
latanoprost; ophthalmic
2.0
9.7
104
535
R03AC03
ATC
terbutaline; inhalant
1.7
9.7
205
1301
7102A
ICD-9 Finland
Diffuse diseases of connective tissue, Sicca syndrome[SYNDROMA SICCUM PRIMARIUM]
55.4
9.7
11
*
WX002
NOMESCO Finland
Sedation and analgesia
1.6
9.7
275
1877
S01EC04
ATC
brinzolamide; ophthalmic
2.4
9.6
67
290
K11.71
ICD-10 Finland
Xerostomy (dry mouth)
4.0
9.6
27
69
R53
ICD-10 Finland
Malaise and fatigue
1.5
9.6
374
2731
SBA00
NOMESCO Finland
Microbiological examinations
2.9
9.6
45
160
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
4.6
9.5
22
48
S18
ICPC
Laceration/cut
1.4
9.5
676
5520
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.1
9.5
94
471
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
3.1
9.4
39
129
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.1
9.4
95
479
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
9.4
9
*
S01
ICPC
Pain/tenderness of skin
2.2
9.4
77
358
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
3.5
9.4
31
89
K07.60
ICD-10 Finland
Snapping jaw
2.2
9.4
80
378
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.8
9.3
150
882
NHQ40
NOMESCO Finland
Amputation of toe
3.7
9.3
29
80
N05CF01
ATC
zopiclone; oral
1.4
9.3
465
3563
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
9.2
104
545
N30.0
ICD-10 Finland
Acute cystitis
1.6
9.2
267
1828
M25.5
ICD-10 Finland
Pain in joint
1.4
9.2
473
3640
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
9.1
124
692
ZX120
NOMESCO Finland
Intravenous
1.8
9.1
135
774
J01FA09
ATC
clarithromycin; systemic
1.5
9.1
422
3182
S01ED02
ATC
betaxolol; ophthalmic
4.5
9.1
22
50
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
4.8
9.1
20
42
S01FA02
ATC
scopolamine; ophthalmic
10.1
9.0
17
17
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.0
9.0
39
133
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
8.9
317
2266
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
7.5
8.9
20
27
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
8.9
119
661
J01MA14
ATC
moxifloxacin; systemic
1.8
8.9
133
765
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.9
8.9
40
139
N06AA09
ATC
amitriptyline; systemic
1.8
8.9
148
879
S76
ICPC
Skin infection other
2.1
8.8
85
421
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
8.8
121
678
H25.1
ICD-10 Finland
Senile nuclear cataract
1.4
8.8
416
3147
K11.2
ICD-10 Finland
Sialoadenitis
2.5
8.8
53
215
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.4
8.8
60
258
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
8.8
197
1269
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.9
8.7
102
542
C08CA05
ATC
nifedipine; systemic
2.0
8.7
91
465
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
50.3
8.7
10
*
N06AB04
ATC
citalopram; systemic
1.5
8.7
296
2098
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
8.7
130
749
D07AC01
ATC
betamethasone; topical
1.4
8.6
502
3939
XKD00
NOMESCO Finland
Uroflowmetry
1.6
8.6
186
1186
S01EA03
ATC
apraclonidine; ophthalmic
4.6
8.6
20
44
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
4.8
8.6
19
40
R01AD08
ATC
fluticasone; nasal
1.5
8.6
385
2883
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
8.5
404
3053
M03BX02
ATC
tizanidine; oral
1.4
8.5
849
7282
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
4.1
8.5
23
57
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
8.5
110
604
R68.2
ICD-10 Finland
Dry mouth, unspecified
6.4
8.5
21
33
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.1
8.5
35
116
E000006, ,
ATC
1.9
8.5
102
548
S01GX02
ATC
levocabastine; ophthalmic
2.0
8.4
88
449
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
8.4
514
4063
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
8.4
123
703
R51.81
ICD-10 Finland
Facial pain NOS
2.8
8.4
42
155
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.2
8.4
66
302
M79.1
ICD-10 Finland
Myalgia
1.6
8.4
215
1430
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
4.9
8.4
18
37
K11.70
ICD-10 Finland
Hypoptyalism
6.7
8.4
20
30
H26.2
ICD-10 Finland
Complicated cataract
4.0
8.3
23
58
H18.2
ICD-10 Finland
Other corneal oedema
+∞
8.3
8
*
H18.9
ICD-10 Finland
Disorder of cornea, unspecified
+∞
8.3
8
*
H192, B005,
ICD-10 Finland
+∞
8.3
8
*
J01DC02
ATC
cefuroxime; systemic
2.1
8.3
78
383
M01AH05
ATC
etoricoxib; oral
1.4
8.2
863
7445
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
8.2
260
1812
121
Kela drug reimbursment
Severe hypofunction of sexual glands
3.0
8.2
36
124
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.9
8.1
97
520
P01AB01
ATC
metronidazole; oral, rectal
1.4
8.1
561
4524
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
8.0
117
668
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.1
8.0
74
361
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
22.1
8.0
11
5
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.3
8.0
60
269
C03CA01
ATC
furosemide; systemic
1.4
8.0
444
3450
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
8.0
119
685
R06AX13
ATC
loratadine; oral
1.6
7.9
204
1356
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
4.7
7.9
18
39
TCG10
NOMESCO Finland
Removal of sutures from cornea
13.1
7.9
13
10
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.0
7.9
86
447
SBB10
NOMESCO Finland
Dental impressions
2.0
7.9
86
447
L04AA24
ATC
abatacept; parenteral
8.5
7.8
16
19
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
7.8
88
463
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
3.7
7.7
24
66
S01EE05
ATC
tafluprost; ophthalmic
2.3
7.7
58
260
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.7
7.7
130
774
114
Kela drug reimbursment
Glaucoma
1.7
7.7
130
775
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
7.7
82
422
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
7.6
74
368
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
7.6
314
2306
UJF32
NOMESCO Finland
Coloscopy
1.4
7.6
363
2740
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.6
501
3997
N03AX09
ATC
lamotrigine; oral
2.2
7.6
65
308
L28
ICPC
Limited function/disability (L)
1.5
7.6
285
2056
WX203
NOMESCO Finland
Infraclavicular plexus blockade
2.8
7.6
37
135
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
7.6
183
1199
WX140
NOMESCO Finland
Parabulbar anesthesy
2.1
7.5
68
329
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
4.1
7.5
20
49
A01AB04
ATC
amphotericin B; local oral
2.0
7.5
77
391
WW200
NOMESCO Finland
Immunization
2.7
7.5
40
153
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
2.8
7.5
37
136
B07.9
ICD-10 Finland
Verruca simplex
2.3
7.5
52
226
M04AA01
ATC
allopurinol; systemic
1.6
7.5
175
1138
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
7.5
274
1967
Z2446
NOMESCO Finland
Social worker
1.9
7.5
95
520
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
7.4
133
806
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
7.4
738
6275
N06AB10
ATC
escitalopram; oral
1.5
7.3
265
1896
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.2
7.3
57
260
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
7.3
404
3126
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.9
7.3
92
502
D06BB03
ATC
aciclovir; topical
2.1
7.3
70
347
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.3
988
8791
H19.0*B02.3
ICD-10 Finland
Zoster scleritis
+∞
7.3
7
*
A05AA02
ATC
ursodeoxycholic acid; oral
3.2
7.3
28
89
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
7.3
206
1400
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.0
7.3
31
105
L29
ICPC
Musculoskeletal sympt/complt other
1.7
7.3
133
812
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
7.2
285
2073
R01AD58
ATC
fluticasone, combinations; nasal
1.4
7.2
318
2362
H26.4
ICD-10 Finland
After-cataract
1.6
7.2
156
995
H40.9
ICD-10 Finland
Glaucoma, unspecified
2.8
7.2
34
122
R96
ICPC
Asthma
1.7
7.2
147
924
G73.7
ICD-10 Finland
Myopathy in other diseases classified elsewhere
30.2
7.2
9
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
7.1
126
761
7102B
ICD-9 Finland
Diffuse diseases of connective tissue, Sicca syndrome[SYNDROMA SICCUM SECUNDARIUM]
20.1
7.1
10
5
C10AC01
ATC
colestyramine; oral
2.5
7.1
43
175
SAA04
NOMESCO Finland
Special examination of mouth
2.0
7.1
73
371
L20.0
ICD-10 Finland
Besnier prurigo
1.9
7.1
91
499
D07AD01
ATC
clobetasol; topical
1.5
7.1
228
1591
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
7.1
179
1184
L84
ICD-10 Finland
Corns and callosities
2.3
7.1
54
244
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.1
183
1217
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
7.1
364
2779
L04AA17
ATC
[U] adalimumab
12.1
7.1
12
10
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.2
7.1
57
264
D11AH01
ATC
tacrolimus; topical
5.6
7.1
19
34
ELA30
NOMESCO Finland
Biopsy of salivary gland
8.8
7.0
14
16
J01CA04
ATC
amoxicillin; systemic
1.4
7.0
1136
10363
UJH02
NOMESCO Finland
Anoscopy
2.1
7.0
61
291
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
7.0
161
1041
D04
ICPC
Rectal/anal pain
3.2
7.0
27
86
K30
ICD-10 Finland
Functional dyspepsia
1.6
7.0
157
1010
D06BX01
ATC
metronidazole; topical
1.6
7.0
154
986
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.0
778
6701
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
7.0
92
510
F02
ICPC
Red eye
2.2
7.0
59
279
L71.8
ICD-10 Finland
Other rosacea
3.0
6.9
29
97
J01AA07
ATC
tetracycline; systemic
1.5
6.9
196
1331
D86.0
ICD-10 Finland
Sarcoidosis of lung
3.7
6.9
21
57
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.9
410
3206
H20
ICD-10 Finland
Iridocyclitis
13.8
6.9
11
8
N80.0
ICD-10 Finland
Endometriosis of uterus
2.8
6.9
32
114
S01EC03
ATC
dorzolamide; ophthalmic
3.3
6.8
25
77
D07AA02
ATC
hydrocortisone; topical
1.6
6.8
180
1203
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
6.8
99
565
D07AC13
ATC
mometasone; topical
1.4
6.8
393
3057
SPAT1263
SPAT
Sampling
1.3
6.8
557
4579
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.0
6.8
71
364
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
5.7
6.8
18
32
M05BA01
ATC
etidronic acid; systemic
5.7
6.8
18
32
S01GX06
ATC
emedastine; ophthalmic
3.7
6.8
21
58
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
3.7
6.8
21
58
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.7
6.8
21
58
05405
ICD-8 Finland
Herpes simplex, Kerato-conjunctivitis herpetica
40.2
6.8
8
*
N03AF01
ATC
carbamazepine; oral, rectal
2.0
6.7
75
393
R4120
NOMESCO Finland
Occupational therapy
1.8
6.7
94
531
H00.1
ICD-10 Finland
Chalazion
2.1
6.7
58
277
H13.1*B00.5
ICD-10 Finland
Herpesviral conjunctivitis
22.6
6.7
9
*
T78.4
ICD-10 Finland
Allergy, unspecified
2.1
6.7
60
291
SPAT1325
SPAT
Vaccination
1.4
6.6
449
3582
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
6.6
358
2753
SPAT1260
SPAT
Consultation of another employee
1.5
6.6
231
1640
J01DA06
ATC
[U] cefuroxime
1.5
6.6
189
1287
M01AC06
ATC
meloxicam; systemic, rectal
1.3
6.6
499
4051
SXA10
NOMESCO Finland
Oral mucosal sampling
3.3
6.6
24
74
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
6.6
114
686
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.0
6.6
28
95
D11AX14
ATC
[U] tacrolimus
8.7
6.6
13
15
SDA03
NOMESCO Finland
Periodontal treatment
1.3
6.5
532
4363
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
3.8
6.5
19
50
Z01.9
ICD-10 Finland
Special examination, unspecified
1.8
6.5
90
506
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
6.5
99
573
R02
ICPC
Shortness of breath/dyspnoea
1.5
6.5
191
1308
H26.3
ICD-10 Finland
Drug-induced cataract
6.2
6.5
16
26
S90.3
ICD-10 Finland
Contusion of other and unspecified parts of foot
2.6
6.5
37
147
A46
ICD-10 Finland
Erysipelas
1.5
6.5
198
1368
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
5.7
6.5
17
30
104
Kela drug reimbursment
Thyroid insufficiency
1.7
6.5
106
628
NDL52
NOMESCO Finland
Tenosynovectomy of hand
3.9
6.4
18
46
R01AD12
ATC
fluticasone furoate; nasal
1.4
6.4
398
3128
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.4
575
4779
H22.0
ICD-10 Finland
Iridocyclitis in infectious and parasitic diseases classified elsewhere
70.1
6.4
7
*
R03BA08
ATC
ciclesonide; inhalant
1.7
6.4
124
768
M01AH02
ATC
rofecoxib; oral
1.5
6.4
180
1220
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
14.4
6.4
10
7
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.7
6.4
123
761
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.3
6.3
48
217
H02.1
ICD-10 Finland
Ectropion of eyelid
3.6
6.3
20
56
L03
ICPC
Low back symptom/complaint
1.4
6.3
395
3109
M02AA07
ATC
piroxicam; topical
1.3
6.3
488
3968
SPAT1301
SPAT
No procedures
1.4
6.3
419
3329
KMAK, ,
NOMESCO Finland
1.3
6.3
663
5634
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.3
6.3
46
205
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
6.3
170
1143
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
18.1
6.3
9
5
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
+∞
6.3
6
*
H16.3
ICD-10 Finland
Interstitial and deep keratitis
+∞
6.3
6
*
H191, B023,
ICD-10 Finland
+∞
6.3
6
*
H04.1
ICD-10 Finland
Other disorders of lacrimal gland
+∞
6.3
6
*
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
+∞
6.3
6
*
M34.0
ICD-10 Finland
Progressive systemic sclerosis
26.8
6.2
8
*
N30.9
ICD-10 Finland
Cystitis, unspecified
1.8
6.2
98
574
M02AA10
ATC
ketoprofen; topical
1.5
6.2
214
1515
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.2
505
4138
M35.1
ICD-10 Finland
Other overlap syndromes
6.3
6.2
15
24
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.1
322
2461
TQW99
NOMESCO Finland
Other minor procedure on skin
1.9
6.1
74
399
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
6.1
150
986
U05
ICPC
Urination problems other
1.9
6.1
77
421
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.1
205
1443
M48.0
ICD-10 Finland
Spinal stenosis
1.5
6.1
179
1225
R74
ICPC
Upper respiratory infection acute
1.4
6.1
404
3207
AA1AD
NOMESCO Finland
CT of head and brain
1.4
6.1
410
3263
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
2.8
6.1
29
105
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
2.4
6.1
38
158
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.1
387
3054
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
3.6
6.0
19
53
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
6.0
296
2236
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.2
6.0
23
73
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
1.9
6.0
75
409

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
140
403
3.73
41.90
2.4
1.6
1.20
1.21
g/l
0.19
135
380
137
390
3.77
41.66
2.4
1.5
0.22
0.24
g/l
2.02
131
369
951
6799
2.10
40.09
10.9
6.0
0.04
0.04
e9/l
1.40
861
5820
950
6790
2.10
40.06
10.9
6.0
0.58
0.58
e9/l
0.10
860
5815
957
6933
2.06
37.92
11.0
6.0
1.79
1.88
e9/l
0.99
884
6091
966
7022
2.07
37.92
11.3
6.2
0.18
0.19
e9/l
1.45
885
6110
35
26
13.76
37.46
1.2
1.7
—
—
—
0
0
111
299
3.93
36.45
1.5
1.2
70.97
63.37
u/ml
0.15
18
33
131
400
3.49
35.78
1.5
1.2
62.19
34.82
u/ml
0.53
20
20
1014
7645
2.02
34.09
14.3
9.4
4.01
4.09
e9/l
0.51
925
6656
121
378
3.40
31.83
1.5
1.2
3.61
2.31
u/ml
0.35
14
34
817
5806
1.90
31.75
17.4
11.5
0.01
0.00
e9/l
0.49
704
4735
152
547
2.98
31.55
2.3
1.8
6.79
8.06
iu/ml
0.24
38
121
862
6241
1.90
31.54
11.4
6.2
0.70
0.68
%
0.62
836
5829
862
6263
1.89
30.95
11.4
6.2
9.10
8.84
%
1.91
838
5864
860
6249
1.89
30.81
11.3
6.1
2.83
2.83
%
0.02
835
5848
230
1033
2.45
30.81
4.5
2.8
10.97
10.79
g/l
0.20
214
949
345
1838
2.14
30.78
1.6
1.3
904.37
491.89
titre
2.21
87
417
874
6406
1.88
30.23
11.1
6.1
26.99
27.38
%
0.46
852
6074
669
4512
1.88
30.07
10.7
5.9
—
—
—
0
0
118
379
3.29
29.67
1.5
1.3
3.19
10.67
u/ml
1.09
20
59
144
524
2.93
29.25
1.6
1.2
0.70
1.00
u/ml
—
9
33
852
6278
1.83
28.08
11.1
6.0
58.10
57.55
%
0.68
835
5995
54
102
5.46
27.43
1.2
1.2
—
—
—
0
0
33
37
9.10
26.89
1.2
1.2
—
—
—
0
0
711
5006
1.80
26.81
5.7
4.0
64.27
110.11
e6/l
1.34
547
3513
640
4389
1.80
26.17
4.6
3.4
20.20
74.01
e6/l
2.91
521
3355
913
6976
1.80
25.59
9.7
6.9
1.21
1.21
mmol/l
0.12
800
6020
66
159
4.30
25.15
1.5
1.3
57.00
65.73
u/ml
—
5
9
52
103
5.19
25.07
2.8
2.1
1252.04
1207.29
e6/l
0.11
47
94
49
95
5.30
24.20
1.2
1.2
—
—
—
0
0
917
7082
1.77
24.08
5.7
4.1
0.03
0.22
estimate
0.45
237
1432
900
6948
1.74
23.31
5.7
4.0
0.00
0.00
estimate
0.50
237
1477
559
3784
1.76
23.15
4.4
3.3
0.42
0.45
e6/l
0.10
440
2789
134
534
2.66
22.82
2.5
1.4
8.27
13.60
iu/ml
—
6
12
827
6258
1.72
22.81
8.6
6.2
1.21
1.21
mmol/l
0.19
770
5776
905
7022
1.73
22.78
5.7
4.1
0.00
4.40
estimate
1.33
247
1514
817
6164
1.72
22.76
6.2
4.9
35.52
35.48
g/l
0.06
764
5773
606
4214
1.74
22.71
6.0
4.1
7.40
7.40
ph
0.26
459
3055
829
6296
1.71
22.39
4.0
3.1
136.41
121.80
ug/l
0.59
786
5848
177
817
2.32
21.97
2.5
1.7
1.30
1.45
g/l
0.54
165
756
457
2957
1.79
21.85
6.8
4.6
—
—
—
0
0
379
2348
1.82
20.79
3.5
2.5
13.20
12.73
umol/l
0.68
353
2190
465
3064
1.75
20.66
3.5
2.7
4.10
6.26
e6/l
3.85
436
2790
551
3830
1.70
20.03
5.4
4.3
—
—
—
0
0
220
1168
2.04
19.07
5.2
4.1
0.59
0.69
%
0.37
81
340
50
122
4.21
18.76
1.5
1.3
2.90
2.94
g/l
0.04
39
91
50
122
4.21
18.76
1.5
1.3
7.68
7.24
g/l
0.21
39
90
50
122
4.21
18.76
1.5
1.3
0.40
0.41
g/l
0.05
37
90
50
123
4.17
18.56
1.5
1.3
—
—
—
0
0
320
1941
1.83
18.56
2.4
2.0
—
—
—
0
0
191
973
2.10
18.48
2.1
2.6
—
—
—
0
0
225
1224
1.99
18.17
5.5
4.3
0.79
1.01
%
0.83
84
367
327
2018
1.79
17.83
3.6
2.5
22.11
22.20
%
0.05
310
1883
43
97
4.53
17.83
2.4
2.1
43.36
39.06
%
0.84
43
97
523
3675
1.65
17.73
2.7
2.3
2.87
2.90
mg/l
0.12
464
3152
67
209
3.31
17.65
1.8
1.7
0.60
0.82
g/l
1.14
53
168
219
1193
1.98
17.59
2.7
2.9
66.37
66.59
g/l
0.15
204
1104
551
3933
1.64
17.50
5.9
4.1
0.00
0.01
estimate
1.34
224
1373
36
71
5.17
17.46
3.0
1.9
580.83
598.36
e6/l
0.04
30
59
215
1167
1.98
17.44
5.7
4.3
0.12
0.13
%
0.05
74
309
37
75
5.03
17.40
3.2
2.1
264.23
231.88
e6/l
0.36
31
67
273
1606
1.86
17.37
3.6
2.6
1.86
1.80
%
0.39
260
1435
345
2178
1.76
17.35
3.5
2.5
2.32
2.32
g/l
0.02
325
2021
558
4008
1.63
17.21
9.4
6.2
—
—
—
0
0
111
464
2.50
17.09
1.5
1.2
—
—
—
0
0
90
340
2.75
16.98
2.7
2.3
12.97
12.81
mg/l
0.05
85
311
731
5615
1.59
16.96
4.9
3.6
6.40
6.25
ph
3.03
412
3122
50
135
3.80
16.37
1.2
1.2
—
—
—
0
0
273
1643
1.81
16.03
1.8
1.4
—
—
—
0
0
1039
8734
1.62
15.99
6.7
5.0
1189.33
2165.07
e6/l
0.63
30
123
582
4287
1.59
15.82
4.1
3.2
1457.02
1339.91
ng/l
0.35
497
3675
788
6226
1.56
15.71
3.2
2.5
80.05
78.27
nmol/l
0.97
727
5607
211
1180
1.92
15.60
6.0
4.6
0.19
0.13
%
0.17
67
283
359
2355
1.69
15.51
3.8
3.2
0.82
0.82
mmol/l
0.33
343
2212
227
1311
1.86
15.18
2.5
2.1
349.84
383.20
nmol/l
1.94
215
1212
333
2152
1.70
15.17
4.1
3.1
2.97
2.86
e6/l
0.07
191
1054
1166
10146
1.68
15.07
12.2
8.2
79.93
79.81
u/l
0.02
1128
9613
355
2341
1.68
14.97
3.8
3.0
1.22
1.21
e6/l
0.02
216
1246
27
47
5.83
14.95
32.2
35.0
94.52
123.10
ug/l
1.44
21
40
390
2637
1.65
14.92
2.1
1.5
2.40
2.47
g/l
0.30
261
1604
72
260
2.86
14.80
1.4
1.1
—
—
—
0
0
572
4253
1.56
14.62
2.5
2.2
158.50
225.89
u/l
1.72
545
4015
644
4929
1.54
14.37
4.1
3.6
2.35
2.36
mmol/l
0.19
591
4470
376
2541
1.64
14.33
1.5
1.3
104.52
33.75
iu/ml
0.65
125
796
29
58
5.08
13.86
3.0
3.2
1294.41
1106.24
u/ml
0.15
29
58
169
913
1.96
13.78
1.6
1.4
—
—
—
0
0
210
1237
1.81
13.08
3.4
2.6
69.77
69.47
e9/l
0.04
154
920
115
553
2.17
12.83
2.5
2.5
3.00
2.99
g/l
0.03
106
508
191
1099
1.85
12.83
3.0
2.4
0.37
0.47
e6/l
0.41
185
1048
120
587
2.14
12.82
2.5
2.4
3.67
3.71
g/l
0.12
111
543
120
588
2.13
12.76
2.5
2.4
7.30
7.44
g/l
0.37
111
543
120
588
2.13
12.76
2.5
2.4
4.20
4.25
g/l
0.27
111
543
63
231
2.80
12.62
3.3
3.0
3.95
4.32
e9/l
0.58
63
231
1366
12603
1.99
12.52
27.0
16.5
21.14
24.34
mg/l
3.89
1217
10432
677
5346
1.49
12.43
2.5
2.2
—
—
—
0
0
382
2675
1.58
12.30
4.0
2.9
512.72
523.36
mosm/kgh2o
0.48
346
2344
537
4062
1.50
12.09
1.8
1.7
20.52
20.39
nmol/l
0.07
465
3428
347
2386
1.59
12.05
1.4
1.3
23.64
12.02
u/ml
0.52
130
896
407
2903
1.55
12.05
3.5
3.0
2.46
2.46
mmol/l
0.02
364
2611
771
6277
1.47
11.96
17.4
15.9
1.27
1.27
inr
0.00
662
5228
255
1628
1.68
11.90
2.7
2.3
127.12
125.19
ug/g
0.04
208
1294
23
43
5.42
11.84
2.2
2.2
6.52
7.02
%
0.09
23
43
221
1372
1.72
11.41
2.0
1.5
—
—
—
0
0
23
45
5.18
11.28
2.2
2.1
29.48
29.56
%
0.01
23
45
664
5305
1.45
11.05
5.7
4.0
0.02
0.11
estimate
0.59
201
1225
1145
10180
1.54
10.83
5.7
4.6
15.03
14.82
pmol/l
2.07
1078
9355
308
2111
1.58
10.71
2.0
1.8
—
—
—
0
0
742
6077
1.44
10.68
2.5
2.2
98.06
96.26
pmol/l
0.42
397
3173
269
1787
1.62
10.66
1.8
1.6
—
—
—
0
0
1167
10438
1.54
10.54
30.0
20.4
13.81
13.69
%
1.99
1155
10292
849
7164
1.43
10.16
8.0
6.6
11.20
11.50
umol/l
0.19
800
6838
919
7867
1.44
10.15
6.1
5.0
6.61
6.69
mmol/l
0.57
886
7482
153
891
1.80
9.83
1.5
1.3
201.26
182.98
u/ml
0.10
139
824
271
1839
1.58
9.76
8.9
5.3
1.07
1.03
mmol/l
1.31
254
1696
563
4438
1.43
9.70
4.1
3.4
—
—
—
0
0
278
1900
1.57
9.70
1.4
1.2
—
—
—
0
0
67
289
2.38
9.70
3.3
3.0
58.06
59.43
%
0.38
67
289
20
24
8.43
9.56
3.1
1.7
0.11
0.21
e9/l
—
13
9
449
3405
1.46
9.49
5.1
4.0
90.68
89.98
%
0.24
437
3335
100
513
2.02
9.44
2.4
2.5
10.25
10.50
g/l
0.16
90
464
295
2057
1.54
9.39
2.5
1.9
28.94
29.47
s
1.08
287
1999
50
191
2.67
9.33
2.7
2.7
—
—
—
0
0
180
1117
1.70
9.25
5.0
3.5
88.29
87.55
ng/l
0.04
154
971
181
1128
1.69
9.15
4.9
3.8
1.22
1.23
mmol/l
0.52
163
961
115
635
1.88
8.76
2.8
1.8
1.52
1.53
g/l
0.02
98
565
57
240
2.43
8.73
1.4
1.4
—
—
—
0
0
173
1079
1.68
8.71
4.7
4.1
—
—
—
0
0
46
175
2.68
8.67
2.0
2.0
32.96
32.21
pg
0.63
46
175
1028
9100
1.42
8.61
4.9
4.2
0.40
5051.20
—
5
20
640
5247
1.38
8.45
5.0
3.9
32.32
66.80
ng/l
1.22
473
3783
52
217
2.45
8.14
1.4
1.5
140.04
154.55
au/ml
—
9
69
472
3699
1.40
8.07
4.0
3.1
0.20
0.03
0.57
15
92
15
15
10.09
8.03
1.8
1.8
—
—
—
0
0
394
3000
1.43
7.91
2.6
1.7
1.28
1.22
mg/l
0.12
313
2322
1284
11925
1.55
7.83
6.9
5.6
1.87
1.92
mu/l
0.80
1223
11013
443
3457
1.40
7.70
3.6
2.7
342.16
340.10
umol/l
0.15
391
3033
142
870
1.70
7.64
2.4
2.5
26.94
22.34
au/ml
0.22
15
85
221
1510
1.54
7.62
1.5
1.3
—
—
—
0
0
194
1287
1.58
7.61
3.0
2.4
33.78
79.51
u/l
0.65
165
1088
104
585
1.84
7.50
2.0
1.9
1.92
1.77
ug/l
0.04
95
516
193
1287
1.57
7.41
2.4
2.2
0.04
0.02
estimate
0.22
46
257
181
1189
1.59
7.40
9.0
8.1
—
—
—
0
0
384
2941
1.41
7.39
1.9
1.7
479.27
18170965.74
pmol/l
1.73
325
2416
325
2421
1.44
7.29
1.9
1.8
1290.65
1180.35
nmol/l
1.44
258
1823
180
1186
1.59
7.27
1.4
1.4
—
—
—
0
0
471
3753
1.37
7.11
4.8
3.5
0.01
0.26
estimate
0.64
197
1171
48
206
2.37
7.10
1.9
1.9
0.99
0.84
%
0.68
36
145
395
3059
1.40
7.08
1.4
1.3
0.70
1.48
u/ml
2.80
115
835
50
222
2.30
6.86
1.3
1.2
242.12
229.68
u/ml
0.15
34
126
69
349
2.02
6.83
1.2
1.2
—
—
—
0
0
106
618
1.77
6.81
1.4
1.2
—
—
—
0
0
181
1213
1.56
6.79
11.8
6.9
10.42
9.91
mmol/l
0.40
173
1164
128
788
1.68
6.77
1.3
1.3
60.45
46.48
au/ml
—
6
58
543
4454
1.34
6.71
3.5
3.2
29.04
33.19
u/l
2.50
514
4216
25
78
3.24
6.71
3.2
2.9
42.00
39.58
%
0.21
13
42
23
68
3.42
6.71
1.1
1.2
—
—
—
0
0
88
487
1.86
6.71
3.4
3.7
98.57
59.72
mg/l
0.44
75
422
88
489
1.85
6.62
3.4
3.7
42.91
56.16
mg/l
0.55
76
424
1389
13235
1.72
6.57
18.5
12.3
25.28
25.20
u/l
0.06
1358
12860
1400
13369
1.77
6.57
32.0
21.7
80.20
76.62
umol/l
2.63
1383
13207
205
1424
1.51
6.52
5.5
3.3
5.83
5.82
kpa
0.05
200
1381
1365
12953
1.63
6.51
28.6
19.8
3.97
3.97
mmol/l
0.11
1346
12673
1363
12931
1.63
6.48
28.2
19.6
139.36
139.63
mmol/l
3.44
1344
12677
76
407
1.91
6.41
4.1
3.1
1.65
1.55
mg/l
0.49
66
368
542
4470
1.33
6.38
2.9
2.4
—
—
—
0
0
19
51
3.76
6.37
11.7
3.5
48.00
62.15
mg/l
0.87
13
40
219
1550
1.48
6.36
3.6
2.7
9.03
7.75
umol/l
0.25
196
1357
203
1422
1.49
6.20
5.7
3.4
7.38
7.38
ph
0.02
124
819
80
441
1.86
6.19
3.1
3.5
24.69
3.30
ratio
0.80
43
257
204
1438
1.48
6.03
6.8
7.6
95.44
95.42
%
0.02
197
1390
196
1371
1.49
6.02
5.6
3.3
1.47
1.87
mmol/l
0.79
171
1186
17
44
3.90
5.99
2.1
1.6
—
—
—
0
0
1361
12943
1.59
5.98
20.5
14.9
—
—
—
0
0
522
4325
1.32
5.83
3.2
2.6
57.97
78.12
u/l
0.56
483
4014
43
193
2.26
5.80
1.4
1.2
13.41
4.57
u/ml
0.73
17
79
38
162
2.38
5.76
2.4
2.4
1.32
0.97
g/24h
0.27
18
95
71
386
1.88
5.75
1.4
1.2
—
—
—
0
0
221
1601
1.45
5.67
6.6
7.3
1.22
0.98
mmol/l
0.33
180
1317
55
275
2.04
5.67
4.4
4.7
2.59
2.81
mmol/l
0.22
34
185
60
312
1.96
5.55
1.7
1.6
—
—
—
0
0
1416
13634
1.76
5.49
38.1
25.1
91.64
91.25
fl
2.71
1402
13481
724
6301
1.29
5.49
3.1
2.8
—
—
estimate
—
0
0
1416
13637
1.75
5.45
38.2
25.1
4.38
4.44
e12/l
5.05
1392
13321
221
1615
1.43
5.41
6.8
7.3
12.60
12.08
kpa
0.71
211
1559
221
1615
1.43
5.41
6.8
7.3
5.07
5.09
kpa
0.09
212
1555
109
684
1.64
5.40
1.4
1.2
—
—
—
0
0
1416
13642
1.75
5.37
38.5
25.3
132.26
133.63
g/l
3.14
1402
13492
1415
13637
1.73
5.26
38.3
25.2
6.70
6.71
e9/l
0.09
1392
13319
1415
13637
1.73
5.26
38.6
25.6
39.80
39.92
%
0.45
1401
13476
1414
13633
1.71
5.13
38.3
25.2
248.85
252.09
e9/l
1.10
1393
13360
178
1262
1.47
5.11
7.2
7.0
1.19
1.35
mmol/l
2.03
171
1241
218
1607
1.42
5.08
6.8
7.3
7.41
7.42
ph
0.17
121
904
1414
13637
1.71
5.07
38.1
25.1
30.40
30.32
pg
1.01
1400
13483
225
1673
1.41
4.99
4.3
3.2
4.55
4.75
e9/l
0.14
197
1448
31
129
2.43
4.98
2.5
2.2
—
—
—
0
0
170
1204
1.46
4.91
4.8
2.8
4.56
4.41
kpa
0.47
164
1170
382
3092
1.32
4.90
6.1
4.2
1.02
1.02
kg/l
0.62
276
2027
56
298
1.91
4.88
4.4
4.0
—
—
—
0
0
186
1345
1.44
4.82
2.3
2.2
0.21
0.21
g/l
0.40
174
1258
57
309
1.88
4.71
1.4
1.5
3198.73
618.40
e6/l
0.60
44
241
14
30
4.70
4.68
1.3
1.2
—
—
—
0
0
36
165
2.21
4.68
1.5
1.2
—
—
—
0
0
14
31
4.55
4.56
1.0
1.0
—
—
—
0
0
68
394
1.76
4.55
1.1
1.1
—
—
—
0
0
56
306
1.86
4.53
1.3
1.4
9.05
28.02
e6/l
0.47
43
228
61
346
1.80
4.39
1.1
1.2
—
—
—
0
0
160
1146
1.44
4.37
2.7
2.5
4.93
7.16
ug/l
2.24
133
1021
234
1794
1.36
4.30
1.3
1.3
—
—
—
0
0
122
832
1.51
4.26
7.8
9.0
24.09
24.30
mmol/l
0.23
117
815
99
646
1.57
4.22
2.6
2.1
0.00
1.24
estimate
0.50
38
202
94
607
1.59
4.19
2.4
2.1
—
—
—
0
0
542
4667
1.25
4.13
4.0
3.3
6.95
7.22
mmol/l
0.75
460
3945
1264
12008
1.34
4.07
7.6
6.5
39.56
39.43
mmol/mol
0.20
1195
11199
34
162
2.12
4.05
1.4
1.2
—
—
—
0
0
31
143
2.19
4.00
1.3
1.5
—
—
—
0
0
28
124
2.28
3.98
5.1
4.0
—
—
—
0
0
1305
12468
1.37
3.97
5.8
5.2
4.62
4.64
mmol/l
0.43
1224
11595
94
616
1.56
3.95
1.1
1.1
—
170.46
titre
—
0
13
12
27
4.47
3.93
1.8
2.2
9.00
10.31
mg/l
0.27
12
19
14
43
3.28
3.91
2.4
1.5
0.00
0.07
estimate
0.49
14
43
13
32
4.09
3.90
7.1
4.2
—
—
—
0
0
1321
12656
1.38
3.86
6.6
5.9
2.65
2.70
mmol/l
1.03
1237
11723
404
3388
1.26
3.82
2.8
2.3
—
—
—
0
0
29
133
2.20
3.81
1.0
1.1
—
—
—
0
0
7
8
8.78
3.77
1.0
1.0
—
—
—
0
0
63
380
1.69
3.71
1.4
1.2
352.00
1108.46
titre
—
5
13
324
2661
1.28
3.62
4.1
3.9
112.52
413.11
ng/l
4.40
251
2097
62
376
1.68
3.59
1.4
1.2
126.67
94.41
titre
—
6
34
77
494
1.59
3.57
2.9
1.8
21.43
20.92
s
0.41
69
450
1295
12399
1.34
3.53
5.7
5.1
1.49
1.49
mmol/l
0.05
1205
11458
14
46
3.06
3.53
2.5
2.5
0.60
0.61
mmol/l
0.40
14
46
10
22
4.57
3.43
1.2
1.0
—
—
—
0
0
13
42
3.11
3.37
1.4
1.7
12.56
14.83
pmol/l
—
7
33
1278
12235
1.31
3.32
6.1
5.3
5.92
5.95
mmol/l
0.30
1178
11199
27
128
2.13
3.31
1.2
1.1
—
—
—
0
0
39
212
1.86
3.28
1.1
1.1
3.90
3.89
u/ml
0.00
20
112
124
897
1.42
3.25
4.2
3.6
5.10
5.17
kpa
0.31
118
866
143
1064
1.38
3.19
1.2
1.2
—
—
—
0
0
127
929
1.40
3.13
1.2
1.2
118.24
134.88
u/ml
0.22
39
358
29
145
2.02
3.11
2.2
2.1
—
—
—
0
0
23
106
2.19
3.03
1.7
1.5
26.77
28.66
%
0.09
15
67
46
271
1.72
3.00
1.2
1.5
—
—
—
0
0
41
234
1.77
2.98
1.7
1.6
—
—
—
0
0
119
869
1.40
2.97
4.1
3.6
7.41
7.42
ph
0.33
99
738
55
341
1.64
2.97
1.9
1.6
16293.39
14060.19
e6/l
0.12
38
241
505
4437
1.21
2.97
4.2
3.4
44.60
46.59
mg/l
0.08
338
2778
603
5395
1.20
2.90
2.1
1.9
1.36
1.34
mmol/l
0.21
506
4535
6
9
6.69
2.87
1.0
1.1
—
—
—
0
0
32
172
1.88
2.82
1.4
1.2
0.22
0.19
nmol/l
0.74
22
130
16
65
2.48
2.79
2.6
1.5
—
—
—
0
0
35
196
1.80
2.73
2.4
2.7
—
—
—
0
0
36
204
1.78
2.71
1.1
1.1
—
—
—
0
0
32
175
1.85
2.69
2.0
1.5
—
—
—
0
0
32
175
1.85
2.69
2.0
1.5
—
—
—
0
0
32
175
1.85
2.69
2.0
1.5
—
—
—
0
0
32
175
1.85
2.69
2.0
1.5
—
—
—
0
0
36
205
1.77
2.67
1.1
1.0
0.78
1.36
u/ml
0.37
16
87
1238
11878
1.25
2.65
4.8
4.3
1.29
1.28
mmol/l
0.13
1138
10868
15
61
2.47
2.62
1.2
1.0
1764.20
1603.93
miu/ml
0.20
15
61
7
15
4.68
2.60
1.9
1.0
—
—
—
0
0
7
15
4.68
2.60
1.9
1.0
—
—
—
0
0
7
15
4.68
2.60
1.9
1.0
—
—
—
0
0
36
207
1.76
2.59
1.1
1.0
—
—
—
0
0
920
8592
1.18
2.59
3.6
3.3
51.57
48.45
u/l
0.37
867
8054
9
25
3.62
2.57
3.1
1.3
—
—
—
0
0
510
4534
1.19
2.57
5.0
4.1
9.75
8.59
mg/mmol
0.22
329
2773
19
88
2.17
2.51
1.7
2.6
7.85
8.84
mmol/l
0.80
19
88
16
69
2.33
2.48
1.3
1.3
156.06
135.44
nmol/l
1.24
16
69
28
151
1.87
2.48
1.1
1.0
0.21
0.45
u/ml
—
10
50
27
144
1.89
2.47
1.3
1.7
—
—
—
0
0
1096
10421
1.19
2.40
31.6
21.4
331.06
331.66
g/l
1.41
1090
10357
111
834
1.36
2.38
3.6
3.5
4.25
4.50
pmol/l
1.73
99
743
30
168
1.80
2.37
1.3
1.2
—
—
—
0
0
51
331
1.56
2.35
2.0
2.1
121.82
128.02
g/l
1.00
34
263
23
119
1.95
2.31
1.0
1.2
—
—
—
0
0
16
72
2.24
2.28
2.8
1.6
—
—
—
0
0
6
13
4.63
2.27
23.2
7.7
5.10
5.43
mmol/l
—
6
13
28
158
1.79
2.18
1.1
1.1
3.61
4.24
u/ml
0.10
13
66
33
196
1.70
2.16
1.1
1.1
0.16
2.17
u/ml
2.40
16
98
6
14
4.30
2.15
1.0
1.1
0.04
0.08
u/ml
—
6
14
23
123
1.88
2.12
1.3
1.1
107.39
110.02
pmol/l
0.10
23
123
115
886
1.32
2.12
1.4
1.2
—
—
—
0
0
30
175
1.73
2.10
1.2
1.0
0.40
2.30
u/ml
3.35
13
82
57
390
1.48
2.09
3.3
3.4
2.52
2.04
index
0.14
25
193
68
482
1.43
2.08
1.5
1.6
8.32
14.05
u/ml
—
10
97
29
169
1.73
2.05
1.4
1.2
—
—
nmol/l
—
0
0
22
118
1.88
2.02
1.6
2.2
15.08
7.73
umol/l
0.34
16
79
25
143
1.76
1.89
1.4
1.9
—
2022.86
—
0
7
20
107
1.88
1.86
2.9
1.6
1955.50
1897.14
ml
0.12
20
102
9
35
2.58
1.80
1.1
1.3
28.11
28.20
s
—
9
35
28
169
1.67
1.78
2.3
1.5
—
—
—
0
0
19
102
1.87
1.76
1.4
1.4
—
—
—
0
0
5
13
3.85
1.71
1.2
1.2
—
—
—
0
0
64
467
1.39
1.71
4.9
3.5
529.52
312.19
mg/l
0.66
29
199
126
1014
1.26
1.71
2.0
1.7
—
—
—
0
0
28
441
0.63
1.67
1.1
1.1
1.52
1.56
g/l
0.41
28
441
58
419
1.40
1.65
1.6
1.5
252.53
279.56
ug/g
0.46
32
250
16
83
1.94
1.64
1.3
1.3
—
—
—
0
0
37
245
1.52
1.63
1.2
1.1
0.50
1.95
u/ml
1.62
20
130
34
221
1.55
1.63
1.3
1.1
—
—
—
0
0
18
98
1.85
1.62
1.2
1.1
—
—
—
0
0
12
56
2.15
1.61
1.0
1.9
40.74
40.10
g/l
0.13
12
56
15
77
1.96
1.59
1.2
1.3
21.98
26.90
umol/l
0.24
15
68
11
50
2.21
1.57
3.5
2.4
13.45
181.40
ug/l
0.51
11
43
106
846
1.27
1.56
2.9
2.3
13.92
12.87
nmol/l
0.66
94
763
10
44
2.28
1.55
1.1
1.1
—
—
—
0
0
10
44
2.28
1.55
1.1
1.1
—
—
—
0
0
10
44
2.28
1.55
1.1
1.1
—
—
—
0
0
5
15
3.34
1.52
1.6
1.5
—
—
—
0
0
35
234
1.51
1.50
2.3
1.7
—
—
—
0
0
103
1277
0.79
1.50
1.9
2.0
3.31
3.45
ratio
0.61
74
1011
9
38
2.38
1.45
1.1
1.1
—
—
—
0
0
9
38
2.38
1.45
1.2
1.5
8.33
7.36
mmol/l
—
9
38
15
80
1.88
1.45
1.4
1.5
75.07
81.08
umol/l
0.51
15
80
33
220
1.51
1.44
1.3
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.1
—
—
—
0
0
64
486
1.33
1.38
2.0
2.7
—
—
—
0
0
26
166
1.58
1.37
1.2
1.0
0.97
1.71
eliau/ml
—
7
71
79
619
1.29
1.37
4.5
3.7
—
—
—
0
0
402
3662
1.13
1.36
1.5
1.4
—
—
—
0
0
88
701
1.27
1.34
2.4
2.4
—
—
—
0
0
46
334
1.39
1.32
2.8
2.1
3919.75
3760.51
u/l
0.02
16
136
32
462
0.69
1.31
1.3
1.2
0.86
0.90
g/l
0.38
32
462
6
24
2.51
1.30
2.0
3.3
—
32.41
—
0
8
49
361
1.37
1.29
5.3
3.1
1.45
1.57
mmol/l
0.71
49
352
53
396
1.35
1.29
1.8
1.6
289.44
285.42
mu/l
0.07
48
361
40
285
1.41
1.28
4.5
3.8
26.45
26.34
mg/l
0.01
28
199
51
379
1.36
1.28
1.6
2.0
2.68
19.33
iu/l
0.56
19
152
11
55
2.01
1.27
1.1
1.4
157.35
174.66
pmol/l
0.20
11
55
66
514
1.30
1.22
1.4
1.6
0.36
0.35
mg/l
0.07
22
228
25
164
1.53
1.20
1.2
1.3
1619.69
1908.45
e6/l
0.16
16
105
21
132
1.60
1.20
1.5
1.1
—
—
—
0
0
22
140
1.58
1.20
1.3
1.4
12251.00
35365.44
e6/l
—
10
71
28
189
1.49
1.19
1.4
1.2
—
—
—
0
0
25
166
1.51
1.15
1.2
1.4
35.56
27.04
u/l
0.62
20
137
77
953
0.80
1.15
1.6
1.8
3.29
3.51
mmol/l
0.98
49
686
5
20
2.50
1.15
1.6
1.5
—
—
—
0
0
7
31
2.26
1.10
1.6
1.2
—
—
—
0
0
5
21
2.39
1.09
2.6
6.3
9.82
7.60
mmol/l
—
5
21
138
1187
1.18
1.05
1.4
1.4
—
—
—
0
0
354
3252
1.12
1.04
5.5
5.6
2.10
2.74
ug/l
1.15
332
2916
85
699
1.23
1.04
4.4
3.5
1.02
1.02
ratio
0.04
77
629
46
350
1.32
1.03
2.0
1.5
—
—
—
0
0
5
22
2.28
1.03
1.4
1.2
—
—
—
0
0
9
48
1.88
1.00
1.3
1.6
—
4440.00
—
0
8
216
1930
1.14
1.00
3.4
3.3
0.69
0.78
ug/l
1.22
151
1247
40
300
1.34
0.99
1.6
1.4
—
—
—
0
0
5
23
2.18
0.98
2.8
2.1
46.60
110.57
u/l
—
5
23
12
69
1.75
0.96
1.3
2.0
—
37.45
—
0
8
125
1077
1.18
0.95
3.2
2.8
6.14
6.08
ph
0.31
95
727
21
141
1.50
0.95
1.4
1.6
62.20
60.03
%
—
10
92
15
93
1.62
0.94
1.1
1.1
68.33
37.54
mg/l
0.80
15
77
6
28
2.15
0.91
1.0
1.0
—
—
—
0
0
169
1496
1.15
0.91
3.6
4.4
5.12
19.00
ug/l
1.61
137
1231
48
376
1.29
0.90
2.0
1.5
—
—
—
0
0
6
30
2.00
0.87
1.5
1.8
—
—
—
0
0
48
379
1.28
0.86
2.0
1.5
—
—
—
0
0
39
300
1.31
0.85
5.9
3.2
7.58
7.61
mmol/l
0.03
39
292
18
121
1.49
0.83
1.1
1.2
—
—
—
0
0
27
197
1.38
0.82
1.6
1.4
0.41
0.37
nmol/l
0.10
21
151
48
382
1.27
0.82
2.0
1.5
—
—
—
0
0
34
258
1.33
0.81
1.7
1.9
—
—
—
0
0
125
1094
1.16
0.81
4.0
3.0
178.98
208.40
ng/l
0.42
111
999
47
378
1.25
0.75
2.0
1.5
—
—
—
0
0
12
75
1.60
0.75
1.9
2.9
15.54
16.19
%
0.25
12
75
9
54
1.67
0.74
1.0
1.1
154.07
187.75
iu/ml
—
9
54
7
38
1.85
0.73
4.6
1.2
—
—
—
0
0
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
65
546
1.20
0.70
3.2
3.5
68.49
809.85
u/ml
1.81
55
472
18
126
1.43
0.70
1.3
1.2
5.50
1.13
u/ml
0.61
12
65
20
144
1.39
0.68
1.3
1.4
—
—
—
0
0
49
402
1.23
0.67
1.4
1.3
—
—
—
0
0
37
294
1.27
0.67
3.1
2.4
72.98
123.65
ug/min
0.56
25
185
11
70
1.58
0.65
1.2
1.2
7.46
7.37
ph
—
6
45
21
154
1.37
0.65
1.2
1.2
—
—
—
0
0
44
359
1.23
0.64
1.6
1.3
275.94
244.11
miu/ml
0.18
16
178
0
20
0.00
0.60
0.0
1.3
—
7.66
—
0
7
18
132
1.37
0.57
1.7
1.3
2933.69
178141.06
e6/l
1.52
13
89
20
150
1.34
0.56
2.2
1.5
18.56
25.48
ng/l
0.93
20
150
9
60
1.50
0.54
1.0
1.0
—
0.39
—
0
12
24
187
1.29
0.53
1.3
1.4
27.13
32.34
g/l
0.92
18
169
500
4806
1.06
0.50
3.5
3.2
—
—
—
0
0
42
354
1.19
0.48
1.1
1.1
—
—
—
0
0
7
48
1.46
0.46
2.0
1.9
—
—
—
0
0
7
50
1.40
0.45
1.3
1.1
—
—
—
0
0
68
602
1.14
0.44
1.1
1.1
—
—
—
0
0
17
131
1.30
0.42
4.2
5.2
144.47
44.51
u/ml
—
6
44
68
608
1.12
0.39
1.4
1.4
33.87
29.85
iu/l
0.42
57
518
11
148
0.74
0.38
4.4
2.6
—
—
—
0
0
11
80
1.38
0.38
5.6
7.2
17.82
225.89
ug/l
—
5
52
13
98
1.33
0.37
1.1
1.0
240.71
310.15
ng/l
—
7
66
5
37
1.35
0.37
1.4
3.1
—
—
—
0
0
37
319
1.16
0.36
1.7
1.4
7.02
10.89
u/l
1.82
29
254
12
90
1.34
0.35
1.6
1.7
83.62
95.38
ng/l
0.42
12
90
5
78
0.64
0.35
1.6
2.3
11.18
3.48
ug/l
—
5
72
5
78
0.64
0.35
1.6
2.2
7.08
2.12
ug/l
—
5
66
5
79
0.63
0.35
1.2
1.1
—
—
—
0
0
13
99
1.32
0.35
1.1
1.0
720.00
686.38
ng/l
—
6
66
34
292
1.17
0.34
1.3
1.4
59.32
59.10
mmol/l
0.01
28
239
11
145
0.76
0.34
1.8
1.3
6.61
7.35
mmol/l
0.80
11
124
10
73
1.37
0.34
1.0
1.1
—
—
—
0
0
16
198
0.81
0.32
1.7
1.6
—
—
—
0
0
11
84
1.31
0.30
1.0
1.6
—
—
—
0
0
7
56
1.25
0.29
1.1
1.4
132.43
164.98
mmol/24h
—
7
56
17
140
1.22
0.27
1.3
1.6
—
—
—
0
0
14
171
0.82
0.26
1.1
1.7
—
—
—
0
0
11
86
1.28
0.26
1.0
1.2
—
—
—
0
0
17
141
1.21
0.26
3.5
3.5
13.50
12.01
index
—
8
79
9
75
1.20
0.25
1.1
1.6
5.83
8.05
ug/l
—
9
67
38
341
1.12
0.24
6.1
4.5
—
—
—
0
0
16
190
0.84
0.23
1.6
1.5
—
—
—
0
0
36
323
1.12
0.23
1.3
1.5
199.52
231.78
pmol/l
0.11
36
315
7
91
0.77
0.22
1.4
1.0
—
—
—
0
0
5
41
1.22
0.22
1.2
1.2
—
—
—
0
0
22
191
1.15
0.22
1.3
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.04
—
0
10
0
12
0.00
0.21
0.0
1.0
—
19.32
—
0
12
11
134
0.82
0.20
1.6
2.3
—
—
—
0
0
21
185
1.14
0.18
2.4
1.9
—
—
—
0
0
22
196
1.12
0.16
1.1
1.1
30.38
96.69
iu/ml
—
8
41
23
207
1.11
0.15
1.3
1.2
—
—
—
0
0
18
160
1.13
0.14
1.2
1.1
—
—
—
0
0
29
266
1.09
0.14
4.3
1.8
1.20
0.91
nmol/l
0.64
22
225
16
141
1.14
0.14
1.4
1.3
—
—
—
0
0
135
1306
1.04
0.13
5.6
4.2
7.35
7.36
ph
0.18
103
928
107
1035
1.04
0.11
1.4
1.4
—
—
—
0
0
10
86
1.16
0.11
1.0
1.1
—
—
—
0
0
18
164
1.10
0.09
1.6
1.8
18.31
21.66
ug/l
0.38
18
159
51
488
1.05
0.09
4.9
3.9
24.11
24.93
mmol/l
1.01
44
450
6
55
1.09
0.09
1.2
1.2
15.00
9.76
mm/h
—
6
55
7
64
1.09
0.08
2.3
2.7
—
—
—
0
0
12
132
0.91
0.06
1.1
1.1
—
—
—
0
0
32
335
0.95
0.06
3.4
3.6
0.82
0.81
nmol/l
0.04
26
274
61
622
0.98
0.03
2.1
1.8
—
—
—
0
0
39
396
0.98
0.00
11.0
10.4
—
—
—
0
0
13
133
0.98
0.00
2.8
2.4
—
—
—
0
0
17
175
0.97
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
352.20
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
399.68
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
4.3
3.9
1.00
0.85
index
—
8
79
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.1
—
11.47
—
0
9
6
64
0.94
-0.00
1.3
1.9
2.50
6.95
nmol/l
—
6
58
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_KERATITISINOTH and mortality.

Females

Parameter HR [95% CI] p-value
H7_KERATITISINOTH 1.172 [1.06, 1.3] 0.003
Birth year 0.997 [0.99, 1.01] 0.498

During the follow-up period (1.1.1998 — 31.12.2019), 1256 out of 5773 females with H7_KERATITISINOTH died.

Males

Parameter HR [95% CI] p-value
H7_KERATITISINOTH 1.287 [1.12, 1.47] < 0.001
Birth year 0.984 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 808 out of 3332 males with H7_KERATITISINOTH died.

Mortality risk

Mortality risk for people of age

years, who have H7_KERATITISINOTH.

N-year risk Females Males
1 0.122% 0.217%
5 0.79% 1.381%
10 1.877% 3.322%
15 3.525% 6.138%
20 6.137% 10.284%

Relationships between endpoints

Index endpoint: H7_KERATITISINOTH – Keratitis and keratoconjunctivitis in other diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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