amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
828 |
4. Check minimum number of eventsNone |
828 |
5. Include endpointsNone |
828 |
6. Filter based on genotype QC (FinnGen only) |
715 |
Control definitions (FinnGen only)
- Control exclude
- E4_METABOLIA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Amyloidosis, other/unspecified
based on the number of shared cases.
Similar with more cases:
- Amyloidosis
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5263 | 2849 | 2321 |
| Only index persons | 3048 | 1579 | 1469 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.08 | 0.06 |
| Only index persons | 0.06 | 0.06 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 67.37 | 66.72 | 68.27 |
| Only index persons | 68.90 | 67.88 | 69.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 715 | 334 | 381 |
| Unadjusted period prevalence (%) | 0.15 | 0.12 | 0.17 |
| Median age at first event (years) | 69.47 | 65.84 | 72.65 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 727
- Matched controls
- 7270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E85.9
ICD-10 Finland
Amyloidosis, unspecified
+∞
311.6
276
*
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
2075.1
170.8
159
*
I43.1*E85.9
ICD-10 Finland
Cardiac amyloidosis
+∞
148.1
137
*
E85.89
ICD-10 Finland
Other amyloidosis
+∞
125.8
117
*
E85.80
ICD-10 Finland
Meretoja sick
+∞
122.4
114
*
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
+∞
120.2
112
*
C90.0
ICD-10 Finland
Multiple myeloma
23.2
106.4
79
38
XW000
NOMESCO Finland
Bone marrow biopsy
9.7
101.0
129
158
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
16.8
98.0
85
57
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
16.5
96.2
84
57
E85.4
ICD-10 Finland
Organ-limited amyloidosis
+∞
87.3
82
*
C03CA01
ATC
furosemide; systemic
4.4
86.1
430
1793
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
8.1
85.8
127
185
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
84.0
79
*
A11CC03
ATC
alfacalcidol; systemic
15.3
78.6
71
51
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
22.4
74.9
56
27
153
Kela drug reimbursment
Lenalidomid
30.8
73.9
49
17
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
+∞
69.9
66
*
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
14.5
63.7
59
44
Z49.1
ICD-10 Finland
Extracorporeal dialysis
16.7
62.0
53
34
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
5.9
61.4
124
246
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
16.9
61.2
52
33
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
18.0
59.6
49
29
A12AA04
ATC
calcium carbonate; oral
16.5
59.4
51
33
TK800
NOMESCO Finland
Hemodialysis
12.2
58.5
60
53
L04AX04
ATC
lenalidomide; oral
26.4
57.2
40
16
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
16.1
54.1
47
31
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
20.2
54.0
42
22
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
14.7
51.5
47
34
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
7.4
50.6
77
114
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
48.2
492
2862
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.2
47.2
285
1232
N18.0
ICD-10 Finland
End-stage renal disease
16.0
47.2
41
27
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
14.9
45.4
41
29
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
15.8
44.5
39
26
I50.9
ICD-10 Finland
Heart failure, unspecified
3.4
44.3
206
758
L01BA01
ATC
methotrexate; systemic
6.6
40.3
68
112
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.1
40.1
216
862
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.0
39.5
233
978
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
39.3
205
802
I50.0
ICD-10 Finland
Congestive heart failure
4.1
38.1
119
333
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.6
37.5
97
235
V03AE01
ATC
polystyrene sulfonate; oral
12.5
37.0
37
31
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.6
35.3
92
224
L04AA01
ATC
[U] ciclosporin
11.4
34.9
37
34
N18.8
ICD-10 Finland
Other chronic renal failure
7.7
34.7
50
69
M04AA01
ATC
allopurinol; systemic
3.2
34.5
171
645
B03XA02
ATC
darbepoetin alfa; parenteral
7.4
34.3
51
73
E85.8
ICD-10 Finland
Other amyloidosis
+∞
33.6
32
*
N08.4
ICD-10 Finland
Glomerular disorders in other endocrine, nutritional and metabolic diseases
+∞
33.6
32
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
58.7
33.6
39
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
33.4
159
584
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
13.3
33.3
32
25
C03DA01
ATC
spironolactone; oral
3.2
32.8
156
573
B03XA01
ATC
erythropoietin; parenteral
12.3
32.7
33
28
I68.0
ICD-10 Finland
Cerebral amyloid angiopathy
+∞
32.5
31
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.3
31.6
55
93
2773B
ICD-9 Finland
Other and unspecified disorders of metabolism, Amyloidosis[AMYLOIDOSIS SECUNDARIA]
+∞
31.5
30
*
N19
ICD-10 Finland
Unspecified kidney failure
5.4
31.1
65
131
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
9.9
30.8
36
38
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.6
30.8
61
117
H16.0
ICD-10 Finland
Corneal ulcer
4.9
30.6
72
161
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.7
30.4
59
111
E85.0
ICD-10 Finland
Non-neuropathic heredofamilial amyloidosis
+∞
30.4
29
*
AA1AD
NOMESCO Finland
CT of head and brain
2.5
30.0
295
1568
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.2
29.2
134
479
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
28.8
130
460
329
Kela drug reimbursment
Lenalidomide
40.8
28.3
35
9
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
9.8
28.1
33
35
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.9
27.9
65
144
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
27.6
82
220
127
Kela drug reimbursment
Transplant complication
10.4
27.5
31
31
H02AB02
ATC
dexamethasone; systemic
3.0
27.4
141
538
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.9
26.7
146
576
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.1
26.3
77
204
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.3
26.0
107
357
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.5
25.3
219
1083
L04AX01
ATC
azathioprine; systemic
5.0
24.7
55
117
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
50.2
24.4
29
6
137
Kela drug reimbursment
Uraemia requiring dialysis
22.2
23.6
34
16
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
23.4
129
508
L04AA06
ATC
mycophenolic acid; systemic
7.6
23.1
33
45
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.9
23.1
123
476
L99.0*E85.9
ICD-10 Finland
Amyloidosis of skin
+∞
23.0
22
*
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
21.5
22.7
33
16
R4120
NOMESCO Finland
Occupational therapy
3.9
22.7
71
197
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.6
22.6
44
83
XF404
NOMESCO Finland
Ambulatory ECG
3.2
22.5
99
343
201
Kela drug reimbursment
Chronic cardiac insufficiency
3.6
22.4
81
248
A04AA01
ATC
ondansetron; systemic, rectal
3.2
22.2
99
346
N07XX08
ATC
tafamidis; oral
+∞
22.0
21
*
Z31.5
ICD-10 Finland
Genetic counselling
4.6
21.4
52
119
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.6
21.3
152
681
ACC51
NOMESCO Finland
Release of median nerve
3.3
21.1
88
295
L01AA03
ATC
melphalan; systemic
29.0
21.1
28
10
I43.1
ICD-10 Finland
Cardiomyopathy in metabolic diseases
+∞
20.9
20
*
ZX120
NOMESCO Finland
Intravenous
3.0
20.9
99
358
ZX112
NOMESCO Finland
Subcutaneous
5.7
20.8
39
71
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.1
20.6
97
349
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
26.4
20.6
28
11
J05AB01
ATC
aciclovir; systemic
2.3
20.3
197
1011
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.3
20.0
53
130
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
20.0
114
456
3011
Kela drug reimbursment
Tafamidis
+∞
19.9
19
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.8
19.8
37
67
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.5
19.5
49
115
WX892
NOMESCO Finland
Monitored bed care
3.2
19.2
82
278
Z49.0
ICD-10 Finland
Preparatory care for dialysis
15.4
19.1
31
21
Z3226
NOMESCO Finland
Physiotherapist
2.4
19.0
158
756
QAJ10
NOMESCO Finland
Browlift
56.6
19.0
22
*
C07AB07
ATC
bisoprolol; oral
2.0
19.0
422
2945
H19.8
ICD-10 Finland
Other disorders of sclera and cornea in diseases classified elsewhere
+∞
18.8
18
*
ZXA05
NOMESCO Finland
Left side
2.2
18.8
223
1237
R06.0
ICD-10 Finland
Dyspnoea
2.1
18.7
244
1403
WW200
NOMESCO Finland
Immunization
6.3
18.7
32
53
Z2446
NOMESCO Finland
Social worker
3.5
18.6
67
204
WW300
NOMESCO Finland
Transfer of autologic stem cells
31.0
18.4
24
8
Z94.0
ICD-10 Finland
Kidney transplant status
14.8
18.2
30
21
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
18.1
194
1031
A07AA09
ATC
vancomycin; oral
7.8
17.9
25
33
WX002
NOMESCO Finland
Sedation and analgesia
2.2
17.7
179
928
R80
ICD-10 Finland
Isolated proteinuria
16.1
17.6
28
18
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
5.7
17.6
33
60
C10AA05
ATC
atorvastatin; oral
2.0
17.5
348
2314
R4110
NOMESCO Finland
Physiotherapy
2.1
17.5
223
1267
Z3231
NOMESCO Finland
Registered nurse
2.1
17.3
222
1262
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.6
17.3
33
61
L04AA13
ATC
[U] leflunomide
5.6
17.3
33
61
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
17.2
300
1904
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
17.1
75
258
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
6.8
17.1
27
41
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.1
17.0
75
259
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.6
17.0
41
93
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
14.5
16.9
28
20
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.1
16.8
36
74
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
16.8
121
541
E85
ICD-10 Finland
Amyloidosis
+∞
16.7
16
*
C09AA05
ATC
ramipril; oral
2.0
16.6
233
1367
B05DA
ATC
Isotonic solutions
20.6
16.5
24
12
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.9
16.5
81
298
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.9
16.4
30
53
ZXD05
NOMESCO Finland
Urgent procedure
2.0
16.4
227
1324
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
16.4
249
1502
CG2T4
NOMESCO Finland
Topography assessment of cornea
13.2
16.3
28
22
J01MA12
ATC
levofloxacin; systemic
2.2
16.3
173
913
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
16.2
110
477
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
25.1
16.1
22
9
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
21.5
16.1
23
11
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
12.6
16.0
28
23
H02.1
ICD-10 Finland
Ectropion of eyelid
6.8
15.8
25
38
N08.4*E85.80
ICD-10 Finland
Glomerular disease in Meretoja's patients
+∞
15.7
15
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
12.7
15.5
27
22
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
6.6
15.5
25
39
WX872
NOMESCO Finland
Intensive care
3.4
15.3
58
183
L04AD01
ATC
ciclosporin; systemic
6.2
15.2
26
43
XF402
NOMESCO Finland
ECG with work load test
2.6
15.1
97
410
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
15.5
15.0
24
16
250, ,
Kela drug reimbursment
4.8
14.8
34
74
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
25.6
14.7
20
8
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
14.7
351
2433
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.5
14.6
24
38
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
11.2
14.6
27
25
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.8
14.6
80
312
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.4
14.5
37
88
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
36.8
14.5
18
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
14.5
135
673
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.5
14.4
35
80
E87.5
ICD-10 Finland
Hyperkalaemia
17.4
14.4
22
13
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
22.8
14.3
20
9
A28
ICPC
Limited function/disability NOS
2.1
14.0
172
953
B01AC04
ATC
clopidogrel; oral
2.2
14.0
145
754
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
14.0
107
490
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
5.7
13.9
26
47
Z49.2
ICD-10 Finland
Other dialysis
18.0
13.9
21
12
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.6
13.9
89
375
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.7
13.9
44
123
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.7
13.9
78
308
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.7
13.8
78
309
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.0
13.7
65
234
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
76.6
13.6
15
*
L01FC01
ATC
daratumumab; parenteral
76.6
13.6
15
*
Z2221
NOMESCO Finland
Medical doctor
2.0
13.6
198
1164
QAJ20
NOMESCO Finland
Subperiosteal facelift
+∞
13.6
13
*
B01AB05
ATC
enoxaparin; parenteral
1.9
13.6
263
1698
H02.2
ICD-10 Finland
Lagophthalmos
16.6
13.5
21
13
9256
FHL
Synovectomy (knee 9311)
142.6
13.5
14
*
ZX108
NOMESCO Finland
Inhalation
13.2
13.5
23
18
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
26.3
13.4
18
7
TFJ02
NOMESCO Finland
Muscle biopsy of heart
21.6
13.4
19
9
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.2
13.2
36
90
N02AX02
ATC
tramadol; systemic, rectal
1.8
13.2
337
2362
H02AB06
ATC
prednisolone; systemic
1.8
13.1
365
2621
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
29.0
13.0
17
6
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.5
12.9
46
139
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
12.9
138
724
H02.3
ICD-10 Finland
Blepharochalasis
2.8
12.9
70
271
1XX32, ,
NOMESCO Finland
51.0
12.9
15
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
12.8
81
339
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.9
12.7
212
1301
S01XA18
ATC
ciclosporin; ophthalmic
12.6
12.7
22
18
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
32.7
12.6
16
5
A46
ICD-10 Finland
Erysipelas
2.1
12.6
132
687
R60.0
ICD-10 Finland
Localized oedema
2.2
12.6
118
588
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
9.5
12.6
25
27
B05DB
ATC
Hypertonic solutions
20.5
12.5
18
9
V03AE02
ATC
sevelamer; oral
20.5
12.5
18
9
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
12.5
188
1114
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
13.5
12.5
21
16
H16.9
ICD-10 Finland
Keratitis, unspecified
5.8
12.5
23
41
L28
ICPC
Limited function/disability (L)
2.0
12.4
173
998
ZXA10
NOMESCO Finland
Bilateral
2.0
12.4
164
930
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
5.2
12.3
25
49
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
12.2
129
673
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
6.1
12.2
21
35
AA1AA
NOMESCO Finland
Head X-ray examination
9.5
12.1
24
26
E86
ICD-10 Finland
Volume depletion
21.7
12.0
17
8
H02.4
ICD-10 Finland
Ptosis of eyelid
3.7
12.0
39
111
C08CA01
ATC
amlodipine; oral
1.7
11.9
318
2237
9283
FHL
Subtalar joint ossification surgery (or triple)
47.5
11.9
14
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.4
11.9
92
422
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
15.0
11.8
19
13
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.6
11.8
28
63
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
11.7
117
597
R55
ICD-10 Finland
Syncope and collapse
2.2
11.7
104
507
CBH25
NOMESCO Finland
Tarsorrhaphy
66.0
11.6
13
*
ZXA00
NOMESCO Finland
Right side
1.8
11.6
215
1358
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.8
11.5
61
233
2773A
ICD-9 Finland
Other and unspecified disorders of metabolism, Amyloidosis[AMYLOIDOSIS PRIMARIA]
+∞
11.5
11
*
H02AB09
ATC
hydrocortisone; systemic
5.0
11.3
24
49
XCK10
NOMESCO Finland
Photography of fundus of eye
2.3
11.3
87
399
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
5.7
11.2
21
38
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
3.0
11.2
50
174
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.3
11.2
91
427
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
11.1
483
3860
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
10.3
11.1
21
21
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
11.0
139
772
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.3
11.0
84
383
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
3.6
11.0
36
103
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
10.9
148
843
NCB20
NOMESCO Finland
Primary total prosthetic replacement of elbow joint
60.9
10.6
12
*
ZXE00
NOMESCO Finland
One hour or less
1.7
10.6
278
1929
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.1
10.6
46
157
K90
ICPC
Stroke/cerebrovascular accident
4.0
10.5
30
78
E87.6
ICD-10 Finland
Hypokalaemia
5.5
10.4
20
37
E85.2
ICD-10 Finland
Heredofamilial amyloidosis, unspecified
+∞
10.4
10
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
10.4
80
366
CG2S4
NOMESCO Finland
Photography of cornea
16.3
10.4
16
10
B01AF02
ATC
apixaban; oral
2.0
10.4
130
720
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
10.3
223
1466
B01AB04
ATC
dalteparin; parenteral
2.9
10.3
49
177
R50.9
ICD-10 Finland
Fever, unspecified
2.0
10.3
123
670
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
10.2
89
429
M01CB01
ATC
sodium aurothiomalate; parenteral
5.4
10.2
20
38
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
10.1
140
801
J05AB11
ATC
valaciclovir; oral
2.0
10.1
120
652
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.9
10.0
160
959
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.7
10.0
32
90
L04AC07
ATC
tocilizumab; parenteral
40.7
10.0
12
*
S18
ICPC
Laceration/cut
1.6
9.9
374
2844
H02AB07
ATC
prednisone; oral
2.0
9.9
112
598
I95.9
ICD-10 Finland
Hypotension, unspecified
4.8
9.8
22
47
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.6
9.8
58
235
C10AA01
ATC
simvastatin; oral
1.7
9.8
319
2335
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
2.9
9.7
45
160
ZZC00
NOMESCO Finland
Graft of fascia
55.8
9.7
11
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.6
9.6
17
15
207
Kela drug reimbursment
Chronic arrhythmias
1.9
9.6
151
901
9294
FHL
Endoprosthesis replacement of the entire hip joint (eg Charnley)
9.3
9.6
19
21
XX9XE
NOMESCO Finland
Other ultrasound examination
10.2
9.6
18
18
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
17.8
9.4
14
8
9272
FHL
Metatarsophalangeal joint resection
17.8
9.4
14
8
CBF99
NOMESCO Finland
Other operation for ectropion
30.5
9.4
12
*
27699
ICD-8 Finland
Amyloidosis
+∞
9.4
9
*
A07EC01
ATC
sulfasalazine; oral, rectal
2.4
9.4
68
303
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
22.0
9.4
13
6
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
22.0
9.4
13
6
R60.9
ICD-10 Finland
Oedema, unspecified
2.7
9.4
52
204
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
9.3
250
1735
B01AA03
ATC
warfarin; systemic
1.8
9.3
170
1061
RS221, ,
NOMESCO Finland
7.4
9.3
21
29
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
9.3
301
2192
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
9.2
144
855
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.1
9.1
95
492
YNB10
NOMESCO Finland
Collection of stem cells for transplant
37.2
9.0
11
*
G51.0
ICD-10 Finland
Bell palsy
3.6
9.0
30
87
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
9.0
122
693
QAJ30
NOMESCO Finland
Other facelift
24.3
8.9
12
5
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.8
8.9
141
841
E83.50
ICD-10 Finland
Hypercalcemia
12.7
8.9
15
12
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
4.1
8.8
24
60
A10BK01
ATC
dapagliflozin; oral
2.3
8.8
66
298
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
8.7
79
387
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.4
8.7
63
281
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.9
8.6
19
40
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
4.9
8.6
19
40
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.0
8.6
39
137
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
3.8
8.5
26
71
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.8
8.5
42
155
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
20.3
8.5
12
6
A12AA12
ATC
[U] calcium acetate
20.3
8.5
12
6
I42.5
ICD-10 Finland
Other restrictive cardiomyopathy
91.1
8.4
9
*
TK810
NOMESCO Finland
Hemofiltration
12.9
8.4
14
11
L03AA02
ATC
filgrastim; parenteral
3.1
8.4
34
112
L04AX03
ATC
methotrexate; systemic
2.1
8.4
79
393
9731/3-C42.1
ICD-O-3
Plasmacytoma, NOS, of bone marrow
+∞
8.3
8
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
8.3
142
865
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
8.3
65
300
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
8.2
49
199
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.0
8.2
36
124
L01AA02
ATC
chlorambucil; oral
14.7
8.2
13
9
L88
ICPC
Rheumatoid/seropositive arthritis
2.8
8.2
40
147
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
4.8
8.1
18
38
205
Kela drug reimbursment
Chronic hypertension
1.6
8.1
217
1494
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.1
8.1
33
109
NFC40
NOMESCO Finland
Repair of hip prosthesis by bone transplant to acetabulum
11.9
8.1
14
12
TK820
NOMESCO Finland
Peritoneal dialysis
17.4
8.1
12
7
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
8.1
110
624
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.6
8.1
46
183
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
8.1
257
1848
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.8
8.1
40
148
E0000UV, ,
ATC
1.6
8.0
284
2093
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
8.0
162
1036
NF1AA
NOMESCO Finland
Hip X-ray examination
2.0
8.0
88
464
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.4
7.9
56
247
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.8
7.9
40
150
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
7.8
99
548
J01DB01
ATC
cefalexin; oral
1.7
7.8
565
4900
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
15.2
7.7
12
8
B74
ICPC
Malignant neoplasm blood other
45.5
7.7
9
*
9289
FHL
Other measure in this category
45.5
7.7
9
*
S97
ICPC
Chronic ulcer skin
2.2
7.7
63
296
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.7
7.6
42
164
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
2.5
7.6
46
188
9314
FHL
Total knee endoprosthesis (also includes patellar part)
18.6
7.6
11
6
L01CB
ATC
Podophyllotoxin derivatives
25.3
7.6
10
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
7.6
262
1914
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
6.3
7.6
19
31
C02AC05
ATC
moxonidine; oral
2.7
7.6
41
159
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
7.6
476
3974
N05CF01
ATC
zopiclone; oral
1.6
7.5
233
1660
212
Kela drug reimbursment
Gout
3.6
7.5
24
68
L04AB01
ATC
etanercept; parenteral
6.6
7.4
18
28
7143C
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[POLYARTHRITIS JUVENILIS SERONEGATIVA]
80.9
7.4
8
*
FFM32
NOMESCO Finland
Occlusion or excision of atrial appendage transvenously with a closing device
80.9
7.4
8
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.1
7.4
20
50
E000001, ,
ATC
1.8
7.4
130
798
A02BC02
ATC
pantoprazole; systemic
1.6
7.4
487
4099
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
7.3
116
689
ZZH31
NOMESCO Finland
Bone allograft, small pieces
6.9
7.3
17
25
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
3.3
7.3
27
84
I50.1
ICD-10 Finland
Left ventricular failure
2.4
7.3
49
211
H18.4
ICD-10 Finland
Corneal degeneration
9.5
7.3
14
15
I49.5
ICD-10 Finland
Sick sinus syndrome
2.6
7.3
43
174
L99.0
ICD-10 Finland
Amyloidosis of skin
+∞
7.3
7
*
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
4.4
7.2
18
42
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
7.2
300
2277
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
15.9
7.2
11
7
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
7.2
71
359
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
7.4
7.2
16
22
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
7.2
104
601
TQW99
NOMESCO Finland
Other minor procedure on skin
2.3
7.2
52
232
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.2
177
1190
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
30.3
7.2
9
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
7.2
252
1844
WW409
NOMESCO Finland
Other aferesis
20.2
7.1
10
5
3AC01, ,
NOMESCO Finland
8.0
7.1
15
19
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
8.9
7.1
14
16
K91
ICPC
Cerebrovascular disease
4.4
7.0
17
39
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
7.0
251
1843
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
7.0
38
148
P01BA02
ATC
hydroxychloroquine; oral
2.1
7.0
66
329
I95.1
ICD-10 Finland
Orthostatic hypotension
2.6
7.0
39
154
TQW40
NOMESCO Finland
Remowal of suture of skin
2.2
7.0
57
268
N30.0
ICD-10 Finland
Acute cystitis
1.8
7.0
108
638
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
6.9
90
502
V03AE03
ATC
lanthanum carbonate; oral
13.9
6.9
11
8
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
13.9
6.9
11
8
C09AA02
ATC
enalapril; systemic
1.7
6.9
155
1017
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.4
6.9
46
198
R13
ICD-10 Finland
Dysphagia
2.2
6.9
59
283
NDG30
NOMESCO Finland
Fusion of wrist, total
11.1
6.8
12
11
N03AF02
ATC
oxcarbazepine; oral
3.1
6.8
27
88
WX720
NOMESCO Finland
Own respiration
2.5
6.8
41
168
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.3
6.8
17
40
1534, ,
Kela drug reimbursment
40.4
6.8
8
*
3060, ,
Kela drug reimbursment
40.4
6.8
8
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
16.9
6.8
10
6
C09CA06
ATC
candesartan; oral
1.6
6.7
171
1156
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
6.7
64
320
JN4AD
NOMESCO Finland
Body CT examination
1.8
6.7
102
599
RD210, ,
NOMESCO Finland
6.5
6.7
16
25
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.9
6.7
31
111
D06BB04
ATC
podophyllotoxin; topical
3.2
6.6
26
84
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.6
6.6
18
33
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.8
6.6
32
117
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.4
6.6
23
69
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
6.6
176
1204
C09CA01
ATC
losartan; oral
1.6
6.6
201
1419
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.9
6.6
19
50
I44.1
ICD-10 Finland
Atrioventricular block, second degree
3.2
6.5
25
80
K65.0
ICD-10 Finland
Acute peritonitis
6.3
6.5
16
26
R4130
NOMESCO Finland
Speech therapy
3.4
6.5
23
70
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.6
6.5
37
148
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
6.4
48
217
QAJ15
NOMESCO Finland
Browlift using video-endoscope
70.4
6.4
7
*
C08CA13
ATC
lercanidipine; oral
1.7
6.4
115
708
I61.6
ICD-10 Finland
Intracerebral haemorrhage, multiple localized
14.5
6.4
10
7
GX2D5
NOMESCO Finland
Sleep oximetry
14.5
6.4
10
7
L04AA11
ATC
[U] etanercept
14.5
6.4
10
7
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
3.2
6.4
25
81
J94.8
ICD-10 Finland
Other specified pleural conditions
3.6
6.4
20
56
L04AD02
ATC
tacrolimus; systemic
8.3
6.3
13
16
L01AA01
ATC
cyclophosphamide; systemic
8.3
6.3
13
16
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
11.1
6.3
11
10
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
9.4
6.3
12
13
L04AB04
ATC
adalimumab; parenteral
3.9
6.3
18
47
R4190
NOMESCO Finland
Nutritional therapy
2.8
6.3
30
109
UKC02
NOMESCO Finland
Cystoscopy
1.7
6.3
138
898
C10AX09
ATC
ezetimibe; oral
1.8
6.3
109
665
9284
FHL
Wrist ossification surgery
18.2
6.3
9
5
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
6.3
78
429
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.2
6.3
52
246
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
6.3
188
1320
QAJ35
NOMESCO Finland
Other correction of loose or redundant skin of head or neck
+∞
6.3
6
*
2773C
ICD-9 Finland
Other and unspecified disorders of metabolism, Amyloidosis[AMYLOIDOSIS CUTIS]
+∞
6.3
6
*
H198, E858,
ICD-10 Finland
+∞
6.3
6
*
M14.4*E85.9
ICD-10 Finland
Arthropathy in amyloidosis
+∞
6.3
6
*
E85.1
ICD-10 Finland
Neuropathic heredofamilial amyloidosis
+∞
6.3
6
*
N02BE01
ATC
paracetamol; systemic, rectal
1.8
6.3
634
5769
N03AX14
ATC
levetiracetam; systemic
3.1
6.2
25
82
FFW96
NOMESCO Finland
Other operation on atria
26.9
6.2
8
*
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
26.9
6.2
8
*
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
26.9
6.2
8
*
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.2
277
2118
A41.9
ICD-10 Finland
Sepsis, unspecified
2.6
6.2
34
133
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
6.2
92
536
WX730
NOMESCO Finland
Conventional respirator
5.4
6.2
17
32
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.7
6.1
33
128
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.8
6.1
18
48
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
2.6
6.1
35
140
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
6.8
6.1
14
21
J01CF02
ATC
cloxacillin; systemic
3.4
6.0
21
63
M10.9
ICD-10 Finland
Gout, unspecified
2.1
6.0
60
305
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
264
245
16.35
261.78
12.5
3.6
63.52
73.71
mg/l
0.14
237
210
263
244
16.32
260.77
12.6
3.6
63.25
45.75
mg/l
0.63
235
212
247
226
16.04
246.13
11.9
3.4
4.27
2.81
ratio
0.35
162
139
144
68
26.16
198.05
4.7
2.3
1.71
1.21
g/24h
0.49
109
32
320
616
8.49
176.24
8.1
2.7
62.98
66.25
g/l
7.21
310
563
201
296
9.00
137.48
7.8
2.2
7.31
7.23
g/l
0.24
195
269
200
296
8.94
136.15
7.8
2.2
4.07
4.19
g/l
0.46
194
270
200
296
8.94
136.15
7.8
2.2
3.37
3.71
g/l
0.79
194
269
193
278
9.09
134.30
8.0
2.3
2.63
2.99
g/l
4.61
187
252
178
262
8.67
120.94
7.9
2.4
2.19
2.05
g/l
0.07
159
225
298
817
5.49
106.78
12.1
5.1
1.13
1.01
mmol/l
8.80
290
748
166
262
7.91
105.38
8.0
2.2
8.39
10.79
g/l
5.54
159
234
229
553
5.59
93.69
13.2
6.2
13.05
10.51
mmol/l
4.36
222
528
143
222
7.77
91.55
8.1
2.3
0.03
0.01
g/l
0.56
131
197
207
474
5.71
89.57
4.8
3.0
9.23
10.98
g/l
4.21
200
437
182
374
6.16
88.50
4.1
1.8
1.21
1.64
g/l
0.85
173
341
139
217
7.68
88.42
8.1
2.3
0.01
0.00
g/l
0.50
122
188
127
200
7.48
79.83
8.6
2.3
0.00
0.00
g/l
-0.00
122
187
278
954
4.10
70.40
3.2
1.9
29.52
29.71
s
0.22
271
923
221
667
4.32
66.36
2.9
2.8
67.12
67.18
e9/l
0.01
180
516
266
958
3.80
61.61
4.8
2.4
20.62
22.59
%
1.94
259
884
275
1024
3.71
60.40
4.9
2.4
2.12
2.27
g/l
4.02
266
940
177
498
4.38
57.67
6.0
3.2
123.33
88.24
ng/l
1.05
156
422
40
17
24.84
55.98
1.1
1.5
—
—
—
0
0
280
1100
3.51
55.90
4.9
2.4
11.15
12.63
umol/l
3.48
272
1020
515
2944
3.57
54.86
13.3
4.7
33.16
35.19
g/l
10.15
498
2728
428
2202
3.29
54.14
8.6
3.1
3515.42
1368.52
ng/l
9.58
403
1882
256
1012
3.36
49.70
5.1
3.3
0.81
0.82
mmol/l
0.54
246
954
506
3032
3.20
46.28
15.5
5.9
1.21
1.21
mmol/l
0.95
482
2746
334
1625
2.95
44.15
5.8
2.8
380.07
349.41
umol/l
4.91
308
1397
536
3384
3.22
43.43
19.8
6.6
1.21
1.21
mmol/l
0.94
482
2863
265
1156
3.03
42.41
2.5
1.9
—
—
—
0
0
373
1959
2.86
42.21
3.2
2.1
179.39
240.96
u/l
0.75
357
1855
115
322
4.05
36.77
2.0
2.1
1.56
1.54
g/l
0.05
105
282
42
10
44.40
34.40
1.3
1.2
—
—
—
0
0
243
1113
2.78
34.36
3.5
1.4
2.24
2.62
g/l
1.55
195
660
253
1195
2.71
33.56
9.3
3.7
160.10
400.25
ng/l
2.35
244
981
201
849
2.89
32.97
2.4
1.8
—
—
—
0
0
295
1515
2.59
32.87
6.1
3.9
84.60
86.43
%
0.54
290
1486
522
3521
2.71
32.33
18.2
9.7
4.43
4.09
e9/l
2.69
474
3067
186
788
2.83
30.04
2.5
1.8
—
—
—
0
0
145
538
3.12
29.73
5.5
2.9
423.51
225.24
ng/l
3.01
139
500
65
138
5.07
29.31
1.4
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
80
202
4.33
29.18
3.6
2.6
0.33
0.33
iu/ml
0.07
49
105
477
3201
2.43
27.87
17.6
16.3
1.30
1.30
inr
0.05
415
2681
406
2554
2.34
27.37
8.2
3.7
64.60
72.96
ng/l
0.13
358
1975
534
3797
2.53
26.99
9.3
4.7
6.63
6.71
mmol/l
0.38
522
3607
74
187
4.29
26.92
1.3
1.6
0.24
0.23
g/l
0.53
68
181
74
192
4.18
25.98
1.3
1.6
1.17
1.14
g/l
0.24
68
187
416
2699
2.27
25.32
4.7
2.9
181.47
148.65
ug/l
2.35
390
2456
60
135
4.75
25.22
4.7
5.2
1120.69
244.00
iu/ml
0.51
13
18
109
375
3.24
25.16
5.9
3.5
1.32
2.15
mmol/l
1.60
81
296
484
3363
2.31
24.67
9.6
6.8
11.19
11.80
umol/l
0.84
475
3203
123
461
3.01
24.50
2.2
1.6
—
—
—
0
0
350
2153
2.21
23.84
5.1
3.3
45.23
121.73
e6/l
1.18
300
1702
241
1279
2.32
23.45
2.1
1.7
1.75
1.59
mg/l
0.15
193
996
149
636
2.69
23.19
7.0
3.1
1.72
2.00
mmol/l
0.44
134
548
373
2378
2.17
22.92
6.4
3.8
64.48
153.65
e6/l
1.66
301
1753
301
1773
2.19
22.54
2.7
2.3
2.90
3.12
mg/l
0.89
269
1512
307
1858
2.13
21.10
5.2
3.2
0.46
0.49
e6/l
0.10
255
1410
111
428
2.88
20.85
2.0
1.6
—
—
—
0
0
50
118
4.48
19.79
1.7
1.4
24.53
31.34
g/l
3.26
42
108
343
2202
2.06
19.77
5.3
3.3
319.85
35.37
mg/l
5.53
268
1386
77
250
3.33
19.39
1.4
2.1
40.23
39.26
u/l
0.14
63
227
401
2761
2.01
18.62
3.3
2.3
77.24
79.82
nmol/l
0.97
378
2396
345
2254
2.01
18.60
6.0
4.0
64.42
6.63
mg/mmol
9.28
263
1370
51
129
4.18
18.46
1.5
2.5
33.30
33.46
umol/l
0.01
43
113
259
1531
2.07
18.40
4.1
2.5
3.87
5.31
e6/l
1.21
246
1397
61
176
3.69
18.39
2.1
1.6
—
—
—
0
0
159
776
2.34
18.24
8.0
7.5
0.65
1.10
mmol/l
0.66
129
622
48
117
4.32
18.23
1.7
1.4
—
—
—
0
0
342
2243
1.99
18.09
5.2
3.2
6.03
7.48
mmol/l
11.53
307
1844
30
23
13.55
17.57
3.7
2.3
39.62
39.97
g/l
0.10
30
23
61
183
3.55
17.35
2.0
1.7
—
—
—
0
0
597
4822
2.33
17.27
17.1
8.3
86.29
79.68
u/l
2.31
582
4526
157
784
2.28
16.97
8.4
7.5
4.80
5.13
kpa
4.24
149
751
143
688
2.34
16.85
3.3
2.7
7.58
8.75
umol/l
0.43
130
610
536
4178
2.08
16.56
6.5
4.7
2778.80
3393.84
e6/l
—
5
64
156
785
2.26
16.52
8.4
7.5
11.73
12.06
kpa
0.44
147
752
188
1024
2.13
16.30
4.3
3.1
3.48
1.99
e6/l
0.99
109
529
22
9
25.14
16.08
6.9
2.3
—
—
—
0
0
572
4595
2.15
15.91
7.6
4.5
19.47
13.18
mm/h
10.73
549
4232
40
99
4.22
14.89
1.7
1.4
113.64
158.94
au/ml
1.39
11
27
40
100
4.17
14.70
1.6
1.4
659.93
1437.10
e6/l
1.86
30
71
60
199
3.20
14.56
1.5
1.3
—
—
—
0
0
26
46
5.82
14.23
1.1
1.0
—
—
—
0
0
310
2095
1.84
13.89
2.1
1.7
20.91
20.53
nmol/l
0.16
274
1698
37
91
4.23
13.89
1.6
1.4
43937.89
121370.84
e6/l
0.48
18
51
209
1252
1.94
13.59
2.0
1.8
1059.73
1177.95
nmol/l
1.04
169
950
331
2298
1.81
13.45
5.0
3.6
2.33
2.35
mmol/l
2.71
310
2048
398
2936
1.79
13.02
3.9
2.8
—
—
estimate
—
0
0
28
58
4.98
12.94
3.3
2.9
—
—
—
0
0
110
527
2.28
12.90
2.4
2.1
378.89
368.77
nmol/l
0.18
104
488
246
1578
1.84
12.82
3.6
2.5
—
—
—
0
0
192
1146
1.92
12.48
4.1
3.0
1.10
1.19
e6/l
0.11
114
657
280
1886
1.79
12.31
4.4
3.2
32.89
33.60
u/l
0.13
265
1759
28
61
4.73
12.21
1.5
1.3
—
—
—
0
0
37
101
3.81
12.08
1.2
1.4
—
—
—
0
0
398
3004
1.72
11.41
2.7
2.1
95.10
96.45
pmol/l
0.21
234
1571
53
189
2.95
11.36
1.3
1.7
—
—
—
0
0
160
930
1.92
11.13
9.1
6.4
103.72
104.48
mmol/l
1.12
160
930
46
154
3.12
11.00
5.1
2.2
121.23
126.73
g/l
0.79
40
120
40
124
3.36
10.83
2.0
1.7
—
—
—
0
0
122
656
2.03
10.58
2.2
2.3
0.20
0.20
g/l
0.42
117
618
46
158
3.04
10.53
1.8
1.4
—
—
—
0
0
108
565
2.07
10.07
2.6
2.4
6.08
7.14
ug/l
0.48
93
500
34
101
3.48
9.84
7.3
6.0
12.99
11.95
mg/l
0.72
34
95
51
197
2.71
9.45
1.7
1.5
—
—
—
0
0
28
76
3.79
9.24
2.0
2.1
—
—
—
0
0
27
72
3.86
9.13
2.0
2.1
—
—
—
0
0
456
3686
1.64
9.10
4.0
3.2
74.77
50.44
u/l
2.30
436
3395
37
122
3.14
9.09
1.8
1.5
—
—
—
0
0
414
3292
1.60
8.64
5.5
4.0
0.00
0.00
estimate
-0.00
100
737
40
144
2.88
8.46
1.9
1.4
—
—
—
0
0
417
3333
1.59
8.42
5.6
4.0
0.00
0.00
estimate
0.50
101
751
25
67
3.83
8.40
2.0
4.8
5.98
6.89
mmol/l
1.15
20
55
18
37
4.96
8.40
3.6
2.6
0.67
1.03
index
1.28
18
37
60
267
2.36
8.30
1.7
1.9
5.88
8.56
iu/ml
0.47
13
64
419
3362
1.58
8.25
5.6
4.0
0.00
0.43
estimate
0.51
87
710
18
38
4.83
8.15
1.4
1.5
—
—
—
0
0
18
38
4.83
8.15
1.4
1.5
—
—
—
0
0
20
47
4.35
7.98
1.0
1.1
—
87.50
—
0
8
273
1996
1.59
7.96
3.3
2.5
60.84
65.85
u/l
0.53
255
1823
98
538
1.95
7.93
2.7
2.6
43.07
34.01
u/l
0.99
82
461
529
4517
1.63
7.73
4.6
4.1
15.14
15.03
pmol/l
0.46
493
4045
59
270
2.29
7.67
2.7
2.0
—
—
—
0
0
60
277
2.27
7.64
2.0
3.0
—
—
—
0
0
67
324
2.18
7.63
2.4
1.9
1.14
2.93
ug/l
1.10
60
285
23
63
3.74
7.51
4.1
2.7
13.00
11.59
index
0.41
18
37
19
45
4.31
7.51
1.1
1.3
—
—
—
0
0
27
83
3.34
7.45
2.6
1.6
89.85
89.59
%
0.06
27
83
370
2931
1.53
7.38
3.0
2.4
—
—
—
0
0
23
64
3.68
7.35
2.3
1.7
—
—
—
0
0
23
64
3.68
7.35
2.3
1.7
—
—
—
0
0
23
64
3.68
7.35
2.3
1.7
—
—
—
0
0
26
79
3.38
7.30
1.7
1.5
—
—
—
0
0
19
33
5.88
7.26
2.4
2.1
—
—
—
0
0
19
33
5.88
7.26
2.4
2.1
—
—
—
0
0
19
33
5.88
7.26
2.4
2.1
—
—
—
0
0
19
33
5.88
7.26
2.4
2.1
—
—
—
0
0
54
246
2.29
7.10
2.2
1.9
—
—
—
0
0
94
530
1.89
7.01
3.6
2.9
39.04
63.44
ml/min/173m2
9.60
55
202
68
342
2.09
7.01
1.4
1.5
—
—
—
0
0
42
174
2.50
6.81
1.5
1.4
—
—
—
0
0
41
169
2.51
6.72
4.6
3.2
2.29
2.26
index
0.02
24
90
33
123
2.76
6.59
1.4
1.3
—
—
—
0
0
33
123
2.76
6.59
1.4
1.3
—
—
—
0
0
35
135
2.67
6.55
1.7
1.4
—
—
—
0
0
43
184
2.42
6.52
2.1
1.6
18890.28
11834.49
e6/l
0.67
32
130
118
732
1.73
6.42
5.4
3.3
—
—
—
0
0
31
114
2.80
6.35
1.4
1.1
210.55
325.03
u/ml
1.19
20
63
11
10
11.15
6.31
12.7
15.5
4.39
5.38
mmol/l
—
11
10
607
5456
1.68
6.30
5.8
5.1
2.10
2.00
mu/l
1.02
566
4901
643
5879
1.81
6.18
40.2
16.4
24.92
26.71
mg/l
0.79
589
4854
45
205
2.27
5.95
1.7
1.4
—
—
—
0
0
196
1418
1.52
5.64
3.1
3.1
2.49
2.46
mmol/l
3.49
179
1276
22
73
3.08
5.41
1.1
1.2
2.00
3.71
u/ml
—
6
42
14
25
5.69
5.39
2.5
2.3
—
—
—
0
0
14
25
5.69
5.39
2.5
2.3
—
—
—
0
0
14
26
5.47
5.24
2.5
2.3
—
—
—
0
0
17
49
3.53
5.20
1.3
1.1
—
—
—
0
0
14
27
5.27
5.10
1.1
1.1
—
—
—
0
0
20
65
3.14
5.10
1.1
1.1
1.79
1.53
g/l
1.67
20
59
16
45
3.61
5.07
1.5
1.3
—
—
—
0
0
18
55
3.33
5.05
1.7
1.4
—
—
—
0
0
18
56
3.27
4.92
1.3
1.4
13.67
13.08
u/l
0.10
18
50
17
51
3.39
4.91
1.1
1.1
—
—
—
0
0
10
13
7.78
4.86
1.5
2.1
0.64
0.62
mmol/l
—
10
13
9
10
9.09
4.79
5.2
4.2
—
—
—
0
0
8
7
11.54
4.79
1.0
1.1
—
—
—
0
0
13
25
5.27
4.78
1.1
1.2
—
—
—
0
0
14
30
4.74
4.70
1.1
1.0
—
—
—
0
0
31
134
2.37
4.65
1.3
1.3
4.13
29.61
e6/l
0.54
23
101
15
43
3.54
4.63
1.5
1.3
—
—
—
0
0
38
180
2.17
4.62
1.4
1.4
424.00
269.87
ug/g
0.48
26
112
33
148
2.29
4.57
2.5
1.7
—
—
—
0
0
31
136
2.34
4.51
1.3
1.3
534.04
1055.31
e6/l
0.25
24
108
17
54
3.20
4.51
1.1
1.1
—
—
—
0
0
16
49
3.32
4.49
1.5
1.3
—
—
—
0
0
9
13
6.99
4.17
1.1
1.2
—
—
—
0
0
14
35
4.06
4.11
2.4
2.0
—
—
—
0
0
18
63
2.90
4.08
1.2
1.1
—
—
—
0
0
13
31
4.25
4.03
1.6
1.5
—
—
—
0
0
13
31
4.25
4.03
1.6
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
28
4.34
3.83
1.2
1.2
—
—
—
0
0
23
96
2.44
3.76
1.7
1.4
—
—
—
0
0
14
39
3.64
3.71
1.1
1.1
—
—
—
0
0
12
30
4.05
3.60
1.7
2.4
487.67
2239.93
u/ml
1.32
12
30
36
186
1.98
3.54
1.5
1.3
—
—
—
0
0
9
17
5.35
3.52
2.0
1.2
—
—
—
0
0
11
28
3.97
3.30
1.1
1.2
—
—
—
0
0
596
5539
1.42
3.29
5.4
4.3
1.30
1.24
mmol/l
1.15
553
4944
13
39
3.37
3.23
1.5
2.3
—
—
—
0
0
10
24
4.21
3.20
1.2
1.5
51.60
60.26
umol/l
—
5
19
11
29
3.83
3.19
1.1
1.0
—
—
—
0
0
610
5705
1.43
3.14
7.2
6.6
39.50
39.36
mmol/mol
0.17
576
5215
14
51
2.78
3.00
1.6
1.1
83.79
114.25
pmol/l
1.78
14
51
35
192
1.86
2.93
1.3
1.7
0.20
0.32
mg/l
—
9
81
515
4715
1.32
2.85
47.9
20.4
14.32
13.79
%
12.24
510
4641
8
18
4.48
2.80
1.0
1.2
—
—
—
0
0
10
28
3.61
2.79
1.8
1.5
62.77
50.31
ug/l
—
10
28
618
5823
1.41
2.77
6.4
5.2
4.32
4.56
mmol/l
7.45
580
5293
5
6
8.38
2.75
7.2
8.5
10.32
4.63
kpa
—
5
6
614
5782
1.40
2.74
6.2
5.1
1.39
1.48
mmol/l
5.86
574
5207
32
176
1.86
2.68
2.4
3.3
0.89
0.79
nmol/l
0.41
18
146
36
206
1.79
2.66
1.6
1.5
0.08
0.08
iu/ml
—
9
32
9
25
3.63
2.58
1.1
1.1
—
—
—
0
0
8
20
4.03
2.57
1.0
1.0
—
—
—
0
0
12
44
2.76
2.55
3.5
1.7
151.00
114.73
ng/l
0.38
12
44
15
63
2.41
2.47
1.2
1.2
122.33
113.45
%
0.57
15
58
12
46
2.64
2.37
1.2
1.4
—
—
—
0
0
12
46
2.64
2.37
1.2
1.4
—
—
—
0
0
11
39
2.85
2.35
1.3
2.1
1365.33
499.97
e6/l
—
6
32
17
79
2.18
2.26
5.2
2.3
10.59
10.42
mmol/l
0.05
17
79
15
66
2.30
2.25
1.1
1.1
—
—
—
0
0
648
6201
1.41
2.24
45.9
19.6
138.93
139.77
mmol/l
10.78
640
6059
135
1075
1.31
2.11
1.3
1.3
29.02
39.34
iu/ml
0.74
51
328
648
6212
1.40
2.10
48.0
19.7
4.02
3.99
mmol/l
1.80
637
6060
209
1762
1.26
2.09
5.3
3.5
0.00
0.07
estimate
0.88
77
578
19
96
2.01
2.07
1.7
1.4
—
—
—
0
0
6
15
4.02
2.04
1.0
1.2
—
—
—
0
0
623
5943
1.34
2.03
7.1
5.9
2.44
2.65
mmol/l
7.36
588
5372
29
175
1.68
1.85
1.3
1.2
—
—
—
0
0
7
23
3.06
1.80
1.0
1.0
2021.29
1114.17
miu/ml
—
7
23
8
30
2.68
1.72
1.0
1.1
—
—
—
0
0
18
96
1.90
1.72
2.8
1.5
206.00
255.88
mu/l
0.75
18
86
10
41
2.46
1.65
1.1
1.1
—
—
—
0
0
175
1485
1.24
1.63
1.8
1.8
46154316.43
16848716.21
pmol/l
0.27
143
1193
295
2639
1.20
1.60
5.5
6.1
2.13
3.13
ug/l
1.73
264
2332
8
32
2.52
1.60
2.1
4.9
—
33.00
—
0
5
10
43
2.34
1.59
1.1
1.1
—
—
—
0
0
10
43
2.34
1.59
1.1
1.1
—
—
—
0
0
10
43
2.34
1.59
1.1
1.1
—
—
—
0
0
89
698
1.31
1.57
1.3
1.4
—
—
—
0
0
26
161
1.64
1.54
1.5
1.7
5.80
4.12
mg/l
0.33
21
125
17
93
1.85
1.52
1.7
1.4
—
—
—
0
0
17
93
1.85
1.52
1.8
1.4
—
—
—
0
0
150
1261
1.24
1.52
1.2
1.2
3.14
1.78
u/ml
0.24
22
319
6
21
2.87
1.51
7.0
2.7
216.83
196.33
u/l
—
6
21
608
5834
1.26
1.50
6.2
5.4
5.92
5.97
mmol/l
0.46
563
5190
17
94
1.83
1.48
1.8
1.4
—
—
—
0
0
17
94
1.83
1.48
1.8
1.4
—
—
—
0
0
122
1006
1.26
1.47
1.2
1.3
37.93
14.24
u/ml
0.79
32
371
10
45
2.24
1.47
1.1
1.1
—
—
—
0
0
652
6316
1.31
1.44
50.0
22.1
109.28
80.47
umol/l
13.88
644
6226
9
39
2.32
1.43
2.4
2.4
—
—
—
0
0
17
96
1.79
1.40
1.8
1.4
—
—
—
0
0
6
23
2.62
1.37
1.0
1.0
—
—
—
0
0
6
23
2.62
1.37
1.3
1.3
144.67
112.87
nmol/l
—
6
16
14
75
1.88
1.35
1.2
1.5
—
—
—
0
0
25
161
1.57
1.30
1.2
1.2
—
—
—
0
0
10
48
2.10
1.28
1.1
1.2
100.10
98.30
%
—
10
43
94
769
1.26
1.23
3.0
4.5
3.74
29.56
ug/l
1.68
78
643
6
26
2.32
1.19
1.0
1.0
—
—
—
0
0
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
643
6249
1.25
1.14
24.4
12.4
23.96
24.76
u/l
1.08
630
6005
37
268
1.40
1.13
2.4
3.6
16.50
4714.22
u/ml
0.68
32
227
12
66
1.83
1.09
1.5
1.7
—
—
—
0
0
234
2124
1.15
0.99
4.6
4.9
22.24
21.67
%
0.23
114
1180
11
61
1.82
0.99
2.3
1.4
1962.20
124.44
u/l
—
5
15
106
902
1.21
0.98
4.9
5.0
34.19
32.44
%
0.94
88
559
5
23
2.18
0.98
1.2
1.1
—
—
—
0
0
20
132
1.53
0.98
1.4
1.2
—
—
—
0
0
10
54
1.86
0.97
1.1
1.1
—
—
—
0
0
652
6376
1.22
0.87
55.7
25.3
92.53
91.69
fl
4.20
645
6275
652
6377
1.22
0.87
55.9
25.4
240.53
241.37
e9/l
0.11
641
6228
652
6378
1.22
0.86
55.8
25.4
4.25
4.43
e12/l
14.36
638
6201
652
6378
1.22
0.86
56.7
25.9
38.77
39.98
%
8.06
645
6271
652
6380
1.21
0.84
56.3
25.6
128.20
134.00
g/l
17.41
647
6278
65
541
1.22
0.78
1.8
1.8
1.48
1.54
%
0.50
51
453
6
34
1.77
0.76
1.5
1.4
99.33
85.68
umol/l
—
6
34
21
149
1.42
0.76
2.8
2.6
145.73
99.22
ug/min
0.21
11
80
5
24
2.09
0.74
1.2
1.1
—
—
—
0
0
5
24
2.09
0.74
1.2
1.1
—
—
—
0
0
593
5778
1.14
0.70
36.1
16.1
66.75
75.50
ml/min/173m2
15.38
574
5407
7
117
0.59
0.68
1.7
1.4
—
—
—
0
0
269
2521
1.11
0.65
2.2
1.9
1.31
1.29
mmol/l
0.17
236
2003
5
30
1.67
0.61
1.0
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.4
—
11.90
—
0
20
55
643
0.84
0.56
1.7
1.4
—
—
—
0
0
269
2537
1.10
0.56
5.8
4.0
0.01
0.03
estimate
0.55
85
625
6
37
1.63
0.55
2.8
3.2
—
—
—
0
0
23
178
1.30
0.53
1.8
1.6
—
—
—
0
0
6
40
1.50
0.51
3.8
2.9
1.33
1.24
%
—
6
40
11
77
1.44
0.45
1.5
1.4
—
—
—
0
0
169
1577
1.09
0.45
3.4
3.5
0.74
0.79
ug/l
0.36
122
1119
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
211
1999
1.08
0.39
6.3
4.0
0.00
0.00
estimate
-0.00
80
673
13
98
1.33
0.37
2.5
2.7
11.67
20.03
mg/l
—
6
40
78
852
0.91
0.33
11.1
6.9
—
—
—
0
0
8
63
1.27
0.28
1.1
1.3
—
—
—
0
0
8
65
1.23
0.27
1.3
1.1
—
—
—
0
0
10
77
1.30
0.26
1.0
1.0
—
—
—
0
0
9
76
1.19
0.24
3.7
3.7
—
—
—
0
0
18
154
1.17
0.21
1.3
1.2
—
—
—
0
0
18
154
1.17
0.21
1.3
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.19
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
26
230
1.14
0.21
1.8
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
9.33
—
0
13
0
13
0.00
0.21
0.0
1.8
—
5.15
—
0
13
21
183
1.15
0.20
1.2
1.2
23.83
3.49
u/ml
—
6
25
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
14
118
1.19
0.19
1.4
1.7
2.50
3.83
iu/l
—
6
41
28
251
1.12
0.19
1.6
1.7
—
—
—
0
0
29
321
0.90
0.18
1.1
1.2
32.10
141.47
u/ml
—
7
128
17
148
1.15
0.17
1.2
1.2
—
1.62
—
0
10
9
108
0.83
0.13
2.7
1.7
—
—
—
0
0
9
109
0.82
0.13
1.2
1.2
1.44
1.56
g/l
—
9
109
150
1458
1.04
0.13
5.6
4.2
1.02
1.02
kg/l
0.55
115
952
21
190
1.11
0.13
1.2
1.2
—
5.29
—
0
8
15
133
1.13
0.12
1.2
1.2
—
44.65
—
0
15
10
115
0.87
0.10
1.4
1.2
0.84
0.91
g/l
—
10
115
5
48
1.04
0.09
1.2
1.2
—
—
—
0
0
5
48
1.04
0.09
1.2
1.2
—
—
—
0
0
38
360
1.06
0.09
1.1
1.3
124.38
194.30
u/ml
0.64
38
330
12
108
1.11
0.07
1.0
1.1
—
—
—
0
0
17
157
1.08
0.07
1.2
2.0
42.94
44.62
nmol/l
0.12
17
149
8
94
0.85
0.06
1.6
1.7
—
—
—
0
0
15
142
1.06
0.02
1.8
1.4
—
—
—
0
0
53
523
1.01
0.01
1.5
1.4
—
—
—
0
0
17
175
0.97
0.00
8.2
2.9
1.27
1.62
mmol/l
0.86
17
170
15
147
1.02
0.00
9.0
3.0
7.61
7.27
mmol/l
0.08
15
142
24
243
0.99
0.00
1.1
1.0
—
—
—
0
0
22
219
1.00
0.00
1.4
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.5
0.27
0.20
nmol/l
—
5
32
5
59
0.85
-0.00
1.0
1.2
—
1.57
—
0
32
0
7
0.00
-0.00
0.0
1.4
—
6.07
—
0
7
0
5
0.00
-0.00
0.0
2.2
—
24.30
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_AMYLNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_AMYLNAS | 5.481 [4.42, 6.8] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.681 |
During the follow-up period (1.1.1998 — 31.12.2019), 696 out of 1370 females with E4_AMYLNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_AMYLNAS | 4.06 [3.17, 5.2] | < 0.001 |
| Birth year | 0.985 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 668 out of 1241 males with E4_AMYLNAS died.
Mortality risk
Mortality risk for people of age
years, who have E4_AMYLNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.4% | 0.707% |
| 5 | 3.508% | 4.19% |
| 10 | 8.544% | 10.612% |
| 15 | 15.418% | 19.136% |
| 20 | 27.346% | 30.589% |
Relationships between endpoints
↥Index endpoint: E4_AMYLNAS – Amyloidosis, other/unspecified
GWS hits: 12
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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