No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
130 |
4. Check minimum number of eventsNone |
130 |
5. Include endpointsNone |
130 |
6. Filter based on genotype QC (FinnGen only) |
127 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Meretoja disease
based on the number of shared cases.
Similar with more cases:
- Amyloidosis, other/unspecified
- Amyloidosis
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 127 | 70 | 57 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | 57.45 | 55.20 | 60.21 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 127
- Matched controls
- 1270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E85.80
ICD-10 Finland
Meretoja sick
+∞
150.8
113
*
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
95.1
79
*
H16.0
ICD-10 Finland
Corneal ulcer
22.6
60.9
53
39
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
183.9
47.6
47
*
H02.3
ICD-10 Finland
Blepharochalasis
13.9
37.8
41
42
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
15.5
33.9
112
412
ZXA10
NOMESCO Finland
Bilateral
7.3
28.1
62
146
XCW99
NOMESCO Finland
Other investigative procedure of eye
8.5
26.1
42
70
CG2T4
NOMESCO Finland
Topography assessment of cornea
161.8
25.7
26
*
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
+∞
24.8
23
*
H04.10
ICD-10 Finland
Dry eye syndrome
7.2
24.4
48
99
QAJ10
NOMESCO Finland
Browlift
+∞
23.7
22
*
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
+∞
21.5
20
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
6.3
21.1
47
108
Z31.5
ICD-10 Finland
Genetic counselling
9.5
20.4
27
35
H02.2
ICD-10 Finland
Lagophthalmos
235.1
20.2
20
*
H19.8
ICD-10 Finland
Other disorders of sclera and cornea in diseases classified elsewhere
+∞
19.2
18
*
S01XA18
ATC
ciclosporin; ophthalmic
110.8
18.1
19
*
WX002
NOMESCO Finland
Sedation and analgesia
5.2
17.7
52
150
ACC51
NOMESCO Finland
Release of median nerve
7.1
16.7
29
51
Z3229
NOMESCO Finland
Other healthcare associate professional
6.6
16.0
30
57
CG2S4
NOMESCO Finland
Photography of cornea
+∞
16.0
15
*
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
+∞
16.0
15
*
N08.4*E85.80
ICD-10 Finland
Glomerular disease in Meretoja's patients
+∞
16.0
15
*
E85.8
ICD-10 Finland
Other amyloidosis
+∞
14.9
14
*
H02.1
ICD-10 Finland
Ectropion of eyelid
31.5
14.8
19
7
E85.0
ICD-10 Finland
Non-neuropathic heredofamilial amyloidosis
+∞
13.8
13
*
QAJ20
NOMESCO Finland
Subperiosteal facelift
+∞
13.8
13
*
E85.89
ICD-10 Finland
Other amyloidosis
+∞
13.8
13
*
CBH25
NOMESCO Finland
Tarsorrhaphy
+∞
13.8
13
*
S01AD03
ATC
aciclovir; ophthalmic
13.2
13.7
24
22
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
20.0
13.0
19
11
XCK10
NOMESCO Finland
Photography of fundus of eye
5.2
12.9
31
74
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
12.7
12
*
H18.4
ICD-10 Finland
Corneal degeneration
+∞
12.7
12
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
+∞
12.7
12
*
E85.9
ICD-10 Finland
Amyloidosis, unspecified
+∞
12.7
12
*
H02.4
ICD-10 Finland
Ptosis of eyelid
13.0
12.6
22
20
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
6.6
12.4
22
39
G51.0
ICD-10 Finland
Bell palsy
24.2
12.4
17
8
R4120
NOMESCO Finland
Occupational therapy
5.9
11.5
23
46
H16.9
ICD-10 Finland
Keratitis, unspecified
22.6
11.5
16
8
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.4
11.1
34
98
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
6.4
11.1
20
36
CBN30
NOMESCO Finland
Shortening of canthal ligament
65.7
10.8
12
*
QAJ30
NOMESCO Finland
Other facelift
65.7
10.8
12
*
ZZC00
NOMESCO Finland
Graft of fascia
119.5
10.6
11
*
S01ED51
ATC
timolol, combinations; ophthalmic
5.2
10.5
24
54
ZXA05
NOMESCO Finland
Left side
3.5
10.5
52
209
S01GX01
ATC
cromoglicic acid; ophthalmic
3.7
10.1
42
150
CBF99
NOMESCO Finland
Other operation for ectropion
59.7
9.8
11
*
S01EE05
ATC
tafluprost; ophthalmic
12.1
9.6
17
16
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
32.8
9.6
12
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.9
9.6
35
114
114
Kela drug reimbursment
Glaucoma
4.8
9.5
24
59
S01EE01
ATC
latanoprost; ophthalmic
5.4
8.9
19
40
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
14.1
8.6
14
11
EAB20
NOMESCO Finland
Plastic repair of lip
+∞
8.4
8
*
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
+∞
8.4
8
*
E85.2
ICD-10 Finland
Heredofamilial amyloidosis, unspecified
+∞
8.4
8
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
15.9
8.4
13
9
H40.0
ICD-10 Finland
Glaucoma suspect
4.3
8.4
24
65
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
8.3
40
155
S01BA01
ATC
dexamethasone; ophthalmic
11.2
8.3
15
15
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
8.7
8.2
17
22
H25.1
ICD-10 Finland
Senile nuclear cataract
3.0
8.1
54
252
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.9
7.9
59
292
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
5.1
7.9
18
40
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
7.7
64
335
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.7
7.6
28
91
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
84.8
7.5
8
*
E0000UV, ,
ATC
2.8
7.5
71
397
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
4.3
7.4
21
56
S18
ICPC
Laceration/cut
2.8
7.4
80
477
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
17.0
7.4
11
7
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
+∞
7.4
7
*
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
7.4
7
*
QAJ15
NOMESCO Finland
Browlift using video-endoscope
+∞
7.4
7
*
CD2S4
NOMESCO Finland
Photography of eye
+∞
7.4
7
*
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
8.8
7.3
15
19
H18.8
ICD-10 Finland
Other specified disorders of cornea
42.4
6.8
8
*
ZXE00
NOMESCO Finland
One hour or less
2.6
6.5
64
357
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
73.4
6.5
7
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
5.6
6.5
18
36
S01AA01
ATC
chloramphenicol; ophthalmic
6.0
6.4
17
32
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
7.7
6.4
14
20
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
28.2
6.3
8
*
QAJ35
NOMESCO Finland
Other correction of loose or redundant skin of head or neck
+∞
6.3
6
*
E85
ICD-10 Finland
Amyloidosis
+∞
6.3
6
*
CBH10
NOMESCO Finland
Plactic repair of canthus
+∞
6.3
6
*
H198, E858,
ICD-10 Finland
+∞
6.3
6
*
N08.4
ICD-10 Finland
Glomerular disorders in other endocrine, nutritional and metabolic diseases
+∞
6.3
6
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
6.2
62
346
S01ED01
ATC
timolol; ophthalmic
7.9
6.1
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
12
15
8.70
5.99
1.6
1.2
—
—
—
0
0
24
84
3.29
5.73
6.8
7.9
24.12
25.25
mmol/l
0.66
24
84
10
11
9.75
5.39
2.9
5.1
1492.50
643.00
mg
—
10
11
59
353
2.25
4.76
3.3
3.1
0.35
0.51
e6/l
0.38
47
250
63
389
2.23
4.69
6.3
4.1
44.04
7.97
mg/mmol
1.62
42
247
41
212
2.38
4.63
2.3
2.9
0.94
1.00
e6/l
0.06
24
94
37
194
2.28
3.99
2.5
3.1
5.45
3.06
e6/l
0.42
20
77
71
509
1.90
3.10
6.3
4.3
34.25
35.83
g/l
1.40
65
485
54
360
1.87
2.91
4.0
3.3
1532.91
1435.21
ng/l
0.07
48
305
71
518
1.84
2.85
9.1
6.5
1.22
1.21
mmol/l
0.14
66
484
14
55
2.74
2.72
1.2
1.3
—
—
—
0
0
6
11
5.66
2.57
1.2
1.1
—
—
—
0
0
11
38
3.07
2.48
6.3
2.4
1.34
1.48
ratio
—
5
21
42
270
1.83
2.48
2.2
2.1
—
—
—
0
0
13
54
2.57
2.28
1.7
2.1
1.34
1.55
g/l
0.57
13
47
13
55
2.52
2.20
7.8
2.9
2.04
1.37
mmol/l
—
7
40
23
127
1.99
2.11
4.0
3.5
—
—
—
0
0
14
64
2.33
2.03
1.9
1.6
—
—
—
0
0
65
495
1.64
2.01
2.4
1.9
105.21
97.00
pmol/l
0.38
29
240
0
51
0.00
1.93
0.0
2.0
—
—
—
0
0
0
46
0.00
1.74
0.0
2.0
—
—
—
0
0
78
637
1.58
1.70
5.0
4.0
0.00
0.00
estimate
-0.00
19
136
77
627
1.58
1.70
5.0
3.9
0.00
0.00
estimate
-0.00
21
145
72
579
1.56
1.67
10.9
7.1
1.22
1.21
mmol/l
0.64
56
498
77
633
1.55
1.58
5.0
3.9
0.00
0.00
estimate
-0.00
22
147
6
139
0.40
1.51
14.3
8.0
—
—
—
0
0
8
34
2.44
1.32
1.1
1.5
—
—
—
0
0
97
858
1.55
1.28
4.8
4.6
18.54
11.34
mm/h
2.75
92
800
32
228
1.54
1.22
2.5
2.7
2.48
2.45
mmol/l
1.05
27
203
110
1009
1.67
1.15
5.6
5.5
2.03
1.93
mu/l
0.38
103
920
7
30
2.41
1.14
1.6
2.0
—
—
—
0
0
36
267
1.49
1.14
1.4
1.6
1.50
1.38
mg/l
0.10
26
216
16
98
1.72
1.09
2.4
3.1
48.78
61.75
ml/min/173m2
—
9
40
60
494
1.41
1.09
2.3
2.0
1.19
1.31
mmol/l
0.95
49
409
7
132
0.50
1.06
6.1
5.0
36.57
32.09
%
—
7
82
63
527
1.39
1.02
3.0
2.5
—
—
estimate
—
0
0
113
1053
1.66
0.99
5.9
5.3
5.90
5.98
mmol/l
0.26
106
979
21
143
1.56
0.97
1.8
2.1
—
—
—
0
0
6
29
2.12
0.90
1.5
1.4
—
—
—
0
0
115
1081
1.68
0.90
20.5
16.1
22.90
24.33
mg/l
0.21
95
883
111
1036
1.57
0.88
6.0
6.6
37.49
39.71
mmol/mol
3.05
104
979
25
182
1.47
0.86
1.7
2.1
—
—
—
0
0
13
81
1.67
0.85
2.0
1.5
—
—
—
0
0
21
149
1.49
0.82
1.8
2.0
—
—
—
0
0
21
149
1.49
0.82
7.0
7.8
1.08
1.09
mmol/l
0.01
15
129
17
117
1.52
0.76
3.4
2.3
351.24
373.50
nmol/l
0.20
17
112
5
24
2.13
0.75
1.2
1.6
—
—
—
0
0
17
235
0.68
0.72
1.4
1.3
7.83
28.11
iu/ml
—
6
84
5
26
1.96
0.71
5.2
2.1
6.82
8.59
pmol/l
—
5
26
5
92
0.52
0.70
1.4
1.3
—
—
—
0
0
48
404
1.30
0.69
3.3
3.5
2.33
2.36
mmol/l
0.69
43
368
5
27
1.89
0.69
1.8
1.3
—
—
—
0
0
74
663
1.28
0.65
9.5
10.9
4.30
4.14
e9/l
0.21
64
573
5
29
1.75
0.64
1.2
1.4
—
—
—
0
0
17
123
1.44
0.62
1.6
2.1
1.31
1.57
%
1.01
12
108
0
23
0.00
0.59
0.0
1.1
—
—
—
0
0
6
36
1.70
0.57
1.3
1.1
—
—
—
0
0
6
39
1.56
0.54
2.2
1.3
—
—
—
0
0
23
181
1.33
0.53
1.9
1.7
1035.47
1327.77
nmol/l
0.78
17
139
0
15
0.00
0.41
0.0
1.9
—
7.00
—
0
7
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
197.48
—
0
19
6
42
1.45
0.36
2.0
1.6
—
—
—
0
0
68
633
1.16
0.32
2.9
3.0
—
—
—
0
0
12
95
1.29
0.27
2.8
2.8
18.30
14.01
nmol/l
1.42
12
88
39
352
1.16
0.27
6.3
3.9
0.00
0.00
estimate
-0.00
19
133
12
96
1.28
0.25
9.2
9.3
0.96
1.46
%
1.78
12
96
113
1102
1.23
0.24
7.2
6.1
2.67
2.71
mmol/l
0.21
102
1027
43
467
0.88
0.24
6.0
3.7
75.77
33.28
ng/l
0.55
38
343
20
172
1.19
0.24
7.1
6.9
104.20
104.21
mmol/l
0.00
20
172
23
261
0.85
0.23
1.3
1.3
0.46
1.63
u/ml
—
5
73
40
366
1.14
0.23
3.2
2.5
47.94
66.62
u/l
0.83
35
337
41
376
1.13
0.22
5.5
5.6
2.27
2.05
ug/l
0.22
36
332
0
10
0.00
0.21
0.0
1.5
—
62.32
—
0
10
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
5.5
—
132.52
—
0
13
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
16
181
0.87
0.15
1.2
1.5
—
—
—
0
0
11
93
1.20
0.15
9.8
9.5
0.40
0.67
%
1.36
11
93
25
229
1.11
0.13
3.9
3.0
0.88
0.80
ug/l
0.23
19
139
74
763
0.93
0.12
3.0
3.2
60.58
49.38
u/l
0.34
65
723
32
300
1.09
0.11
4.4
4.7
23.10
21.67
%
0.23
20
148
5
43
1.17
0.10
1.4
1.2
1.35
1.61
g/l
—
5
43
5
43
1.17
0.10
1.2
1.5
—
—
—
0
0
5
43
1.17
0.10
1.4
1.2
0.81
0.89
g/l
—
5
43
110
1086
1.10
0.08
6.2
5.3
1.39
1.49
mmol/l
1.77
99
1003
49
474
1.05
0.07
5.2
3.8
0.06
0.00
estimate
0.48
18
122
11
100
1.11
0.05
1.5
2.2
—
—
—
0
0
110
1089
1.08
0.05
6.5
5.4
4.58
4.68
mmol/l
0.46
100
1014
36
351
1.04
0.02
4.3
3.3
0.00
0.00
estimate
-0.00
17
115
16
168
0.95
0.02
1.6
1.5
—
—
—
0
0
25
242
1.04
0.02
1.8
1.8
540.47
491.13
pmol/l
0.24
19
207
24
248
0.96
0.02
5.1
4.2
1.02
1.02
kg/l
0.23
18
168
10
93
1.08
0.02
1.6
2.0
—
—
—
0
0
13
124
1.05
0.00
3.8
3.0
2.05
2.39
mmol/l
0.13
13
105
105
1045
1.03
0.00
5.3
4.5
1.39
1.28
mmol/l
0.70
95
963
0
5
0.00
-0.00
0.0
3.6
—
4.62
—
0
5
0
7
0.00
-0.00
0.0
10.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
1.10
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
10.22
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.00
—
0
6
0
9
0.00
-0.00
0.0
4.1
—
1.33
—
0
9
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
11.00
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: E4_MERETOJA_DISEASE – Meretoja disease
GWS hits: 17
This endpoint is excluded (different definition than used in FinnGen).