Other and/or unspecified nontoxic goitre

E4_GOITRENAS

goiter: Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E04.8, E04.9
  • Hospital discharge: ICD-9 2419
  • Cause of death: ICD-10 E04.8, E04.9
  • Cause of death: ICD-9 2419

2 out of 7 registries used, show all original rules.

3740

4. Check minimum number of events

None

3740

5. Include endpoints

None

3740

6. Filter based on genotype QC (FinnGen only)

3363

Control definitions (FinnGen only)

Control exclude
E4_THYROID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 22270 18757 3408
Only index persons 20487 17456 3031
Unadjusted period prevalence (%)
Whole population 0.47 0.54 0.10
Only index persons 0.56 0.64 0.12
Median age at first event (years)
Whole population 57.28 56.61 61.03
Only index persons 56.26 55.63 59.94

-FinnGen-

Key figures

All Female Male
Number of individuals 3363 2806 557
Unadjusted period prevalence (%) 0.87 1.00 0.26
Median age at first event (years) 55.36 53.87 62.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3497
Matched controls
34970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E04.8
ICD-10 Finland
Other specified nontoxic goitre
564.4
307.7
402
8
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
5421.1
307.7
481
*
H03BB01
ATC
carbimazole; oral
111.6
307.7
287
28
E03
ICD-10 Finland
Other hypothyroidism
113.1
307.7
319
31
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
307.7
402
*
E03.89
ICD-10 Finland
Other specified hypothyroidism
117.5
307.7
301
28
104
Kela drug reimbursment
Thyroid insufficiency
806.7
307.7
807
13
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
282.0
307.7
285
11
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
25.7
307.7
273
115
H03AA01
ATC
levothyroxine sodium; systemic
95.7
307.7
1891
425
BAA60
NOMESCO Finland
Total thyroidectomy
7093.3
307.7
602
*
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
440.1
307.7
959
30
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
281.1
307.7
1177
63
T86
ICPC
Hypothyroidism/myxoedema
86.9
307.7
345
44
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
1779.7
307.7
2860
88
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
141.5
307.7
832
77
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
28.3
307.7
250
95
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
118.4
307.7
342
32
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
35.0
293.7
186
56
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.6
287.4
503
862
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
103.5
232.4
120
12
2504
FHL
Unilateral resection or enucleation
792.0
228.9
223
*
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
723.8
209.8
205
*
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
346.2
197.7
198
6
T81
ICPC
Goitre
50.1
185.1
107
22
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
182.9
174
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
10.9
167.5
183
176
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
+∞
159.6
152
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
156.4
149
*
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
372.3
144.0
144
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
248.4
140.2
143
6
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
49.8
134.7
78
16
BA1AE, ,
SPAT
11.9
134.0
137
119
E04
ICD-10 Finland
Other nontoxic goitre
44.9
133.3
79
18
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
128.9
1688
9970
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
111.0
106
*
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
+∞
106.8
102
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
97.5
1111
6032
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
92.4
1490
9207
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
4.1
88.7
258
668
106
Kela drug reimbursment
Hypoparathyroidism
49.7
84.4
49
10
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
817.2
81.8
80
*
R13
ICD-10 Finland
Dysphagia
2.8
65.5
351
1327
E83.51
ICD-10 Finland
Hypocalcemia
12.9
64.1
62
49
T85
ICPC
Hyperthyroidism/thyrotoxicosis
29.6
61.6
41
14
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
162.9
61.1
64
*
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
130.4
60.0
64
5
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
59.8
1533
10596
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
25.0
59.6
42
17
EP1AE, ,
SPAT
4.7
59.0
140
309
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.9
53.3
273
1005
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
51.0
827
4919
ZXE00
NOMESCO Finland
One hour or less
1.7
50.4
1425
9984
T72
ICPC
Benign neoplasm thyroid
17.6
48.9
40
23
Z71.8
ICD-10 Finland
Other specified counselling
1.7
48.1
1290
8879
R06.0
ICD-10 Finland
Dyspnoea
1.8
47.9
1047
6800
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
474.2
47.4
47
*
A11CC03
ATC
alfacalcidol; systemic
4.4
44.5
113
263
R03AC02
ATC
salbutamol; inhalant
1.6
44.3
1989
15536
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
43.2
1364
9731
Z2221
NOMESCO Finland
Medical doctor
1.7
43.1
1012
6672
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
12.1
41.9
42
35
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
40.7
39
*
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
402.1
40.2
40
*
2411A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic multinodular goitre
+∞
39.7
38
*
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
39.7
38
*
WX402
NOMESCO Finland
General anaesthesia
1.7
39.2
833
5319
A02BC05
ATC
esomeprazole; systemic
1.6
38.5
1512
11285
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
38.2
1082
7453
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
381.5
38.1
38
*
N02BE01
ATC
paracetamol; systemic, rectal
2.2
37.3
3202
29076
ZXA00
NOMESCO Finland
Right side
1.7
36.3
981
6659
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
36.2
1038
7153
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
361.0
36.0
36
*
ZXA05
NOMESCO Finland
Left side
1.7
35.7
916
6129
N02AX02
ATC
tramadol; systemic, rectal
1.6
35.7
1513
11430
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
+∞
35.5
34
*
A02BC02
ATC
pantoprazole; systemic
1.6
35.2
2484
21055
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
+∞
33.4
32
*
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
33.4
32
*
R49.01
ICD-10 Finland
Functional dysphonia
3.0
33.3
152
524
M79.6
ICD-10 Finland
Pain in limb
1.5
33.1
1638
12737
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
32.4
506
2932
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
+∞
32.3
31
*
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
+∞
32.3
31
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
32.0
1090
7784
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
39.5
31.2
39
10
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.0
31.1
346
1787
R21
ICPC
Throat symptom/complaint
1.7
31.1
685
4383
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
31.0
823
5525
R53
ICD-10 Finland
Malaise and fatigue
1.6
30.2
889
6116
Z3226
NOMESCO Finland
Physiotherapist
1.7
29.6
654
4181
ZX114
NOMESCO Finland
Intramuscular
5.0
29.3
63
128
2506
FHL
Thyroidectomy
+∞
29.2
28
*
GB1AA
NOMESCO Finland
Tracheal X-ray examination
+∞
29.2
28
*
R4110
NOMESCO Finland
Physiotherapy
1.6
28.4
1007
7217
R42
ICD-10 Finland
Dizziness and giddiness
1.6
28.2
882
6140
A02BC03
ATC
lansoprazole; oral
1.5
27.7
1037
7514
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.9
27.0
131
467
UJF32
NOMESCO Finland
Coloscopy
1.5
26.4
937
6697
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
26.3
1594
12708
M25.5
ICD-10 Finland
Pain in joint
1.5
26.3
1202
9064
C07AB07
ATC
bisoprolol; oral
1.5
26.2
1649
13241
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
4.3
26.1
68
162
H02AB06
ATC
prednisolone; systemic
1.5
25.7
1622
13011
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
25.6
378
2144
J01DB01
ATC
cefalexin; oral
1.6
25.3
2808
25157
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
25.2
836
5874
A97
ICPC
No disease
1.6
25.2
717
4866
R01AD09
ATC
mometasone; nasal
1.4
24.1
1542
12348
4CJ01, ,
NOMESCO Finland
+∞
24.0
23
*
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
24.0
23
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
23.8
993
7316
J01AA02
ATC
doxycycline; systemic
1.5
23.7
2725
24354
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
3.9
23.5
68
175
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
23.5
927
6748
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
23.3
665
4507
J01FA10
ATC
azithromycin; systemic
1.4
22.9
1911
16004
M03BX02
ATC
tizanidine; oral
1.4
22.9
2102
17910
SPAT1336
SPAT
Request for examination
2.5
22.9
143
581
R07.0
ICD-10 Finland
Pain in throat
2.0
22.7
243
1235
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
231.5
22.6
23
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
22.5
391
2326
R52.9
ICD-10 Finland
Pain, unspecified
1.8
22.3
380
2247
A48
ICPC
General and Unspecified, Clarification/discussion RFE/demand
2.1
22.0
217
1070
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
+∞
21.9
21
*
J01FA06
ATC
roxithromycin; oral
1.4
21.8
1365
10828
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
21.7
1469
11811
K30
ICD-10 Finland
Functional dyspepsia
1.7
21.4
428
2648
A29
ICPC
General symptom/complaint other
1.6
21.2
491
3156
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
3.2
21.2
82
257
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
21.2
668
4621
R02
ICPC
Shortness of breath/dyspnoea
1.6
21.1
485
3111
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
20.9
681
4742
Z3231
NOMESCO Finland
Registered nurse
1.5
20.9
874
6413
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
20.8
20
*
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
20.8
20
*
A02BA02
ATC
ranitidine; systemic
1.5
20.8
664
4601
ZXD20
NOMESCO Finland
Day surgery
1.7
20.8
459
2912
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
20.7
1419
11402
ZXA10
NOMESCO Finland
Bilateral
1.6
20.7
642
4420
S21
ICPC
Skin texture symptom/complaint
1.6
20.7
556
3705
UJD02
NOMESCO Finland
Gastroscopy
2.2
20.5
183
868
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
20.4
689
4833
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
18.4
20.4
31
17
J02AC01
ATC
fluconazole; systemic
1.4
20.3
1476
11969
L17
ICPC
Foot/toe symptom/complaint
1.4
20.3
1101
8480
R03BA05
ATC
fluticasone; inhalant
1.6
20.0
607
4158
N03AX16
ATC
[U] pregabalin
1.5
19.9
791
5735
BAA30
NOMESCO Finland
Excision of thyroid isthmus
57.9
19.9
23
*
EB1AA, ,
SPAT
2.0
19.6
234
1236
S04
ICPC
Lump/swelling localized
1.7
19.4
396
2460
UJC01
NOMESCO Finland
Scopy of lower throat
4.6
19.4
45
98
R03DC03
ATC
montelukast; oral
1.6
19.4
584
3992
G47.3
ICD-10 Finland
Sleep apnoea
1.5
19.2
641
4477
M54.5
ICD-10 Finland
Low back pain
1.4
19.2
1240
9827
Z01.2
ICD-10 Finland
Dental examination
1.4
19.2
1539
12653
M01AB05
ATC
diclofenac; systemic, rectal
1.4
19.1
2217
19359
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
18.8
18
*
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
18.8
18
*
E06.3
ICD-10 Finland
Autoimmune thyroiditis
17.2
18.7
29
17
A02BC01
ATC
omeprazole; systemic
1.4
18.6
918
6926
A11CC02
ATC
dihydrotachysterol; oral
20.9
18.6
27
13
C07AA05
ATC
propranolol; systemic
1.5
18.6
642
4516
R4130
NOMESCO Finland
Speech therapy
2.7
18.5
98
367
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
18.3
616
4306
R49.08
ICD-10 Finland
Other specified dysphonia
2.7
18.3
97
363
R51.80
ICD-10 Finland
Headache
1.6
18.3
517
3478
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
3.8
18.2
56
151
S18
ICPC
Laceration/cut
1.4
18.2
1585
13168
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
18.1
626
4401
G44.2
ICD-10 Finland
Tension-type headache
1.6
18.0
481
3193
J01FA09
ATC
clarithromycin; systemic
1.4
17.9
1031
7988
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
17.8
2355
20881
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
+∞
17.7
17
*
A04
ICPC
Weakness/tiredness general
1.6
17.7
528
3595
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
17.5
300
1774
E06.9
ICD-10 Finland
Thyroiditis, unspecified
28.9
17.4
23
8
R60.0
ICD-10 Finland
Localized oedema
1.6
17.3
450
2966
A01
ICPC
Pain general/multiple sites
1.6
17.2
380
2407
N01
ICPC
Headache
1.7
17.2
351
2179
R01AD08
ATC
fluticasone; nasal
1.4
17.1
930
7126
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
17.0
458
3045
N06AX11
ATC
mirtazapine; oral
1.4
16.8
1126
8932
J01DA01
ATC
[U] cefalexin
1.4
16.8
2030
17653
R05
ICPC
Cough
1.4
16.8
867
6577
B01AB05
ATC
enoxaparin; parenteral
1.4
16.7
1089
8595
WX002
NOMESCO Finland
Sedation and analgesia
1.5
16.7
653
4700
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
16.7
16
*
WZC30
NOMESCO Finland
Teaching
1.5
16.6
543
3767
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
16.5
1550
12954
Z01.7
ICD-10 Finland
Laboratory examination
1.5
16.4
567
3979
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
16.2
1006
7868
L28
ICPC
Limited function/disability (L)
1.5
16.2
680
4960
R05
ICD-10 Finland
Cough
1.4
16.2
737
5459
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
16.2
1599
13457
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
16.1
317
1948
B60
ICPC
Blood and Immunity, Result test/procedure
3.5
16.0
55
160
D06
ICPC
Abdominal pain localized other
1.7
16.0
324
2007
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
16.0
888
6816
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
15.8
707
5217
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
15.8
362
2313
H02AB07
ATC
prednisone; oral
1.6
15.7
456
3079
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
15.6
15
*
S29
ICPC
Skin symptom/complaint other
1.4
15.6
709
5246
R07.3
ICD-10 Finland
Other chest pain
1.6
15.5
353
2252
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
15.5
461
3132
H53.1
ICD-10 Finland
Subjective visual disturbances
1.8
15.4
254
1485
M02AA07
ATC
piroxicam; topical
1.4
15.4
1221
9914
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
15.4
1768
15168
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
15.4
1466
12240
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
15.3
441
2974
N06AX21
ATC
duloxetine; oral
1.6
15.2
399
2632
A27
ICPC
Fear of other disease NOS
1.9
15.2
186
992
A60
ICPC
General and Unspecified, Result test/procedure
2.1
15.1
153
763
L01
ICPC
Neck symptom/complaint
1.5
15.1
567
4043
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
15.1
313
1950
N17
ICPC
Vertigo/dizziness
1.5
15.1
463
3166
E07.89
ICD-10 Finland
Other specified disorders of thyroid
45.2
15.1
18
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
15.0
205
1132
A99
ICPC
Disease/condition unspecnature/site
1.6
14.9
353
2274
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
14.8
235
1358
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.4
14.8
99
416
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
14.8
565
4039
D01
ICPC
Abdominal pain/cramps general
1.6
14.8
415
2780
N03AX12
ATC
[U] gabapentin; oral
1.5
14.7
536
3795
K02.1
ICD-10 Finland
Caries of dentine
1.3
14.7
1815
15688
R06.5
ICD-10 Finland
Mouth breathing
1.8
14.7
248
1459
P01AB01
ATC
metronidazole; oral, rectal
1.3
14.7
1370
11380
2260A
ICD-9 Finland
Benign neoplasm of thyroid gland[NEOPLASMA BENIGNUM GLANDULAE THYREOIDEAE]
+∞
14.6
14
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
14.6
2074
18288
EB1SA, ,
SPAT
2.0
14.5
170
892
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
6.6
14.5
23
35
R60.9
ICD-10 Finland
Oedema, unspecified
1.8
14.4
207
1162
UKC02
NOMESCO Finland
Cystoscopy
1.5
14.4
421
2848
L12
ICPC
Hand/finger symptom/complaint
1.5
14.3
582
4209
D19
ICPC
Teeth/gum symptom/complaint
1.4
14.3
989
7841
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
14.2
436
2981
M01AH05
ATC
etoricoxib; oral
1.3
14.0
2084
18438
R29
ICPC
Respiratory symptom/complaint other
1.8
14.0
228
1330
L03
ICPC
Low back symptom/complaint
1.4
13.9
987
7854
Z00.8
ICD-10 Finland
Other general examinations
1.7
13.8
256
1546
F29
ICPC
Eye symptom/complaint other
1.6
13.8
367
2427
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
13.8
490
3449
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.6
13.8
348
2274
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
13.8
1019
8157
L15
ICPC
Knee symptom/complaint
1.4
13.7
900
7071
WZC30, ,
SPAT
1.6
13.7
292
1832
E03.8
ICD-10 Finland
Other specified hypothyroidism
+∞
13.5
13
*
BAA99
NOMESCO Finland
Other operation on thyroid gland
140.5
13.5
14
*
XF402
NOMESCO Finland
ECG with work load test
1.6
13.4
323
2089
H02AB04
ATC
methylprednisolone; systemic
1.5
13.4
473
3327
R00.2
ICD-10 Finland
Palpitations
1.7
13.4
275
1709
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
21.2
13.3
19
9
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
13.3
312
2004
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
13.2
798
6179
SFA20
NOMESCO Finland
Two-surface restoration
1.3
13.2
1839
16062
BA3AT, ,
SPAT
13.8
13.2
22
16
M79.1
ICD-10 Finland
Myalgia
1.5
13.2
482
3412
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
13.1
564
4117
A12AA04
ATC
calcium carbonate; oral
3.2
13.1
50
156
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
13.1
194
1100
L82
ICD-10 Finland
Seborrhoeic keratosis
1.4
13.1
677
5111
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
9.3
12.9
26
28
J01FF01
ATC
clindamycin; systemic
1.4
12.9
835
6533
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
12.9
461
3247
C03CA01
ATC
furosemide; systemic
1.3
12.9
939
7484
M01AE02
ATC
naproxen; oral, rectal
1.3
12.9
1812
15829
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
12.8
433
3017
GD1AA, ,
SPAT
1.5
12.8
471
3339
R03BA02
ATC
budesonide; inhalant
1.4
12.7
584
4316
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
12.5
399
2744
R06AE07
ATC
cetirizine; oral
1.3
12.5
1457
12391
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
+∞
12.5
12
*
S48
ICPC
Skin, Clarification/discussion RFE/demand
5.2
12.5
25
48
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
12.5
1627
14047
T71
ICPC
Malignant neoplasm thyroid
130.5
12.4
13
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.2
12.4
99
450
U07
ICPC
Urine symptom/complaint other
1.6
12.4
300
1940
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.7
12.4
213
1261
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
12.4
260
1624
R03AC03
ATC
terbutaline; inhalant
1.5
12.4
450
3180
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
12.4
388
2660
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
12.3
269
1699
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
2.0
12.3
131
667
M01AH01
ATC
celecoxib; oral
1.4
12.3
611
4577
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
12.2
882
7011
J45.1
ICD-10 Finland
Nonallergic asthma
1.7
12.2
234
1427
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
12.2
765
5950
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.7
12.2
219
1312
M54
ICD-10 Finland
Dorsalgia
1.5
12.1
381
2613
K80
ICPC
Cardiac arrhythmia NOS
1.6
12.1
298
1937
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
12.0
2295
20773
M79.7
ICD-10 Finland
Fibromyalgia
2.0
12.0
135
700
R01AD12
ATC
fluticasone furoate; nasal
1.3
12.0
955
7698
L08
ICPC
Shoulder symptom/complaint
1.4
12.0
772
6028
WZB00, ,
SPAT
1.7
12.0
248
1544
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
11.9
770
6013
E66.8
ICD-10 Finland
Other obesity
1.8
11.9
172
967
J01CA04
ATC
amoxicillin; systemic
1.3
11.9
2678
24788
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.7
11.8
205
1217
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.6
11.8
266
1691
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
11.8
270
1723
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
11.6
1240
10399
A03
ICPC
Fever
1.4
11.6
476
3442
C07AB02
ATC
metoprolol; systemic
1.4
11.6
609
4600
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
11.5
673
5172
XCH00
NOMESCO Finland
Eye pressure measurement
1.8
11.5
171
971
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.2
11.5
44
138
1930A
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA PAPILLARE THYREOIDEAE]
+∞
11.5
11
*
R74
ICPC
Upper respiratory infection acute
1.3
11.4
974
7917
DQE10
NOMESCO Finland
Injection of foreign material into vocal cord
8.3
11.3
24
29
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
11.2
369
2554
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
2.3
11.1
85
380
P06
ICPC
Sleep disturbance
1.5
11.1
377
2628
WYA00, ,
SPAT
2.9
11.0
51
179
Z50.5
ICD-10 Finland
Speech therapy
3.1
11.0
44
142
U02
ICPC
Urinary frequency/urgency
1.4
11.0
549
4110
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.5
10.9
378
2643
K43
ICPC
Cardiovascular, Other diagnostic procedure
3.1
10.9
44
143
D12
ICPC
Constipation
1.9
10.8
123
642
H57.1
ICD-10 Finland
Ocular pain
1.9
10.7
127
671
M01AG02
ATC
tolfenamic acid; oral, rectal
1.4
10.7
502
3716
L48
ICPC
Musculoskeletal, Clarification/discussion RFE/demand
3.3
10.7
39
119
J01MA02
ATC
ciprofloxacin; systemic
1.3
10.7
1178
9895
R68.2
ICD-10 Finland
Dry mouth, unspecified
3.6
10.6
34
95
J37.0
ICD-10 Finland
Chronic laryngitis
2.0
10.6
109
548
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
10.5
527
3942
S54
ICPC
Skin, Repair/fix-suture/cast/prosth device
2.0
10.4
111
565
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
10.4
518
3870
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
10.4
818
6563
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.5
10.4
377
2662
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
1.8
10.3
150
846
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.6
10.3
228
1443
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.5
10.3
307
2081
C03DA01
ATC
spironolactone; oral
1.5
10.3
363
2548
J01DA09
ATC
[U] cefadroxil
1.3
10.2
799
6400
U01
ICPC
Dysuria/painful urination
1.5
10.2
293
1970
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.8
10.2
153
872
SFA10
NOMESCO Finland
One-surface restoration
1.3
10.2
1699
14977
WX704
NOMESCO Finland
Intubation
1.6
10.2
252
1639
Z50.1
ICD-10 Finland
Other physical therapy
1.7
10.2
181
1083
E66.01
ICD-10 Finland
Obesity due to excess calories
1.6
10.2
269
1777
XA402
NOMESCO Finland
ENMG
2.2
10.1
84
389
K48
ICPC
Cardiovascular, Clarification/discussion RFE/demand
4.1
10.1
27
66
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
10.0
426
3099
C08CA01
ATC
amlodipine; oral
1.3
9.9
1239
10542
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
1.8
9.9
146
827
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
2.2
9.9
83
386
R83
ICPC
Respiratory infection other
1.3
9.9
707
5591
24210
ICD-8 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre
16.7
9.9
15
9
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
9.9
1150
9703
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
9.9
1145
9656
R61.9
ICD-10 Finland
Hyperhidrosis, unspecified
2.8
9.8
48
174
2409X
ICD-9 Finland
Simple and unspecified goitre, Goitre, unspecified
20.1
9.8
14
7
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.5
9.8
360
2547
U72
ICPC
Urethritis
2.0
9.8
99
496
A11
ICPC
Chest pain NOS
1.5
9.8
281
1891
M01AC06
ATC
meloxicam; systemic, rectal
1.3
9.7
1215
10333
R96
ICPC
Asthma
1.5
9.7
335
2341
N05AH04
ATC
quetiapine; oral
1.4
9.7
468
3479
L04
ICPC
Chest symptom/complaint
1.6
9.7
212
1340
2509
FHL
Other measure in this category
55.1
9.6
11
*
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
9.6
644
5039
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
9.6
212
1341
CK2S4, ,
SPAT
2.6
9.6
55
216
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.3
9.6
823
6671
WW200
NOMESCO Finland
Immunization
2.3
9.6
73
327
T99
ICPC
Endocr/metab/nutrit disease other
2.6
9.5
55
217
R12
ICD-10 Finland
Heartburn
1.5
9.5
272
1827
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.4
9.5
450
3332
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.6
9.5
199
1243
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
9.5
596
4621
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.8
9.4
136
766
M01AH02
ATC
rofecoxib; oral
1.4
9.4
419
3068
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
9.4
751
6024
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.9
9.4
108
565
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.4
9.4
370
2650
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
9.4
688
5454
R03BB04
ATC
tiotropium bromide; inhalant
1.5
9.4
285
1940
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
9.4
9
*
2462A
ICD-9 Finland
Other disorders of thyroid, Cyst of thyroid
+∞
9.4
9
*
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
+∞
9.4
9
*
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
+∞
9.4
9
*
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
2.4
9.4
62
261
R52.2
ICD-10 Finland
Other chronic pain
1.8
9.4
125
688
C10AA05
ATC
atorvastatin; oral
1.3
9.4
1313
11308
H29
ICPC
Ear symptom/complaint other
1.4
9.3
401
2920
C10AA07
ATC
rosuvastatin; oral
1.3
9.3
1082
9111
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
9.3
2087
18946
N05CF01
ATC
zopiclone; oral
1.3
9.3
1008
8418
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
9.3
2993
28437
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
9.2
471
3531
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.6
9.2
242
1595
A23
ICPC
Risk factor NOS
1.5
9.2
282
1922
R49.09
ICD-10 Finland
Unspecified dysphonia
2.8
9.2
45
163
K85
ICPC
Elevated blood pressure
1.3
9.2
596
4639
R4120
NOMESCO Finland
Occupational therapy
1.6
9.2
197
1238
D21
ICPC
Swallowing problem
2.5
9.2
55
221
N02BF01
ATC
gabapentin; oral
1.5
9.2
340
2408
XF600
NOMESCO Finland
Bloodpressure measurement
1.7
9.1
176
1077
M01AB55
ATC
diclofenac, combinations; oral
1.6
9.1
220
1424
C03AA03
ATC
hydrochlorothiazide; oral
1.5
9.1
289
1987
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
9.1
673
5343
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.4
9.0
501
3807
E23.05
ICD-10 Finland
Lack of TSH
36.8
9.0
11
*
D02
ICPC
Abdominal pain epigastric
1.6
9.0
208
1333
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
2.4
9.0
57
236
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.0
8.8
89
446
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.7
8.8
157
941
K29.1
ICD-10 Finland
Other acute gastritis
2.7
8.8
46
173
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.8
8.8
135
776
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.5
8.8
233
1541
E66.00
ICD-10 Finland
Metabolic syndrome
1.7
8.8
150
889
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.7
8.8
140
814
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.6
8.7
213
1381
N30.0
ICD-10 Finland
Acute cystitis
1.3
8.7
627
4952
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.6
8.7
212
1374
M54.2
ICD-10 Finland
Cervicalgia
1.5
8.7
255
1723
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.7
8.7
165
1007
S01
ICPC
Pain/tenderness of skin
1.7
8.6
147
871
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
8.6
336
2406
A98
ICPC
Health maint/preventive medicine
1.6
8.5
3319
32205
J01EA01
ATC
trimethoprim; systemic
1.3
8.5
915
7614
M77.0
ICD-10 Finland
Medial epicondylitis
2.1
8.5
80
390
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
8.5
2013
18288
BA2AT
NOMESCO Finland
Biopsy of thyroid with ultrasound quidance
27.6
8.5
11
*
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
2.4
8.5
54
224
L29
ICPC
Musculoskeletal sympt/complt other
1.5
8.5
291
2032
WX110, ,
SPAT
1.7
8.4
167
1029
A08
ICPC
Swelling
1.6
8.4
192
1225
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
8.4
208
1353
Z71.9
ICD-10 Finland
Counselling, unspecified
1.5
8.4
246
1661
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
1.6
8.4
215
1410
A02BC04
ATC
rabeprazole; oral
1.5
8.4
276
1910
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
8.4
167
1031
24100
ICD-8 Finland
Non-toxic nodular goitre, Endemic
+∞
8.3
8
*
C73.93
ICD-10 Finland
Anaplastic thyroid carcinoma (thyroid)
+∞
8.3
8
*
T90
ICPC
Diabetes non-insulin dependent
1.3
8.3
693
5585
J38.3
ICD-10 Finland
Other diseases of vocal cords
2.8
8.3
39
139
L13
ICPC
Hip symptom/complaint
1.3
8.2
693
5589
K99
ICPC
Cardiovascular disease other
2.0
8.2
79
390
TQW40, ,
SPAT
1.4
8.2
319
2282
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.5
8.2
284
1988
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
8.1
776
6359
M01AX17
ATC
nimesulide; oral
1.3
8.1
767
6277
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
8.1
383
2832
A10BJ06
ATC
semaglutide; parenteral
1.7
8.1
145
870
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.5
8.1
252
1724
N06AB03
ATC
fluoxetine; oral
1.4
8.0
355
2596
H02AB09
ATC
hydrocortisone; systemic
2.4
8.0
55
236
D04
ICPC
Rectal/anal pain
2.4
8.0
52
218
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
8.0
507
3932
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
8.0
928
7791
A03FA02
ATC
cisapride; oral, rectal
1.5
8.0
234
1583
B01AF02
ATC
apixaban; oral
1.4
7.9
400
2993
N04BC05
ATC
pramipexole; oral
1.5
7.9
238
1618
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
7.9
1400
12304
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
7.9
339
2467
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
7.8
1265
11007
R06AX27
ATC
desloratadine; oral
1.3
7.8
863
7198
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.5
7.8
268
1872
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
2.6
7.8
42
161
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.6
7.8
165
1036
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
2.3
7.8
56
246
L02
ICPC
Back symptom/complaint
1.4
7.7
311
2236
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
7.7
792
6545
C09CA01
ATC
losartan; oral
1.3
7.7
808
6694
E20.8
ICD-10 Finland
Other hypoparathyroidism
45.1
7.7
9
*
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
15.0
7.7
12
8
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.7
266
1859
M54.6
ICD-10 Finland
Pain in thoracic spine
1.5
7.7
222
1496
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.4
7.7
382
2851
J01FA01
ATC
erythromycin; systemic
1.4
7.7
379
2825
UJF32, ,
SPAT
1.8
7.7
105
584
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.7
7.6
141
854
L09
ICPC
Arm symptom/complaint
1.6
7.6
159
995
F45.8
ICD-10 Finland
Other somatoform disorders
1.6
7.6
184
1193
J45
ICD-10 Finland
Asthma
1.4
7.6
321
2330
J35.0
ICD-10 Finland
Chronic tonsillitis
1.8
7.6
116
667
J01DA06
ATC
[U] cefuroxime
1.4
7.5
424
3226
R49.03
ICD-10 Finland
Atrophic dysphonia
2.7
7.5
40
152
B02AA02
ATC
tranexamic acid; systemic
1.3
7.5
486
3777
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
7.5
675
5486
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.4
7.5
352
2601
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.6
7.5
184
1197
XKD03
NOMESCO Finland
Urethral pressure profilometry
2.0
7.4
78
397
S22
ICPC
Nail symptom/complaint
1.5
7.4
207
1384
A06AD11
ATC
lactulose; oral
1.4
7.4
422
3215
LCA06
NOMESCO Finland
Biopsy of endometrium
1.4
7.4
429
3277
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.6
7.4
180
1167
RD210, ,
NOMESCO Finland
2.4
7.4
47
195
K02.0
ICD-10 Finland
Caries limited to enamel
1.3
7.4
536
4233
J01MA06
ATC
norfloxacin; oral
1.4
7.4
430
3289
D20
ICPC
Mouth/tongue/lip symptom/complaint
1.6
7.4
151
940
K29.8
ICD-10 Finland
Duodenitis
3.4
7.4
26
78
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
7.4
696
5690
R01AD58
ATC
fluticasone, combinations; nasal
1.3
7.4
718
5894
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.4
7.3
331
2429
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
7.3
258
1810
ZYC01
NOMESCO Finland
Remote contact by phone
1.6
7.3
173
1115
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.8
7.3
111
637
Z3229
NOMESCO Finland
Other healthcare associate professional
1.5
7.3
232
1595
C739, ,
ICD-10 Finland
+∞
7.3
7
*
M48.0
ICD-10 Finland
Spinal stenosis
1.4
7.3
376
2822
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.3
7.3
825
6892
RL210, ,
NOMESCO Finland
4.1
7.3
19
46
DFF00
NOMESCO Finland
Pure tone audiometry
1.4
7.3
318
2322
H01
ICPC
Ear pain/earache
1.4
7.2
338
2497
H25.1
ICD-10 Finland
Senile nuclear cataract
1.2
7.2
903
7630
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.0
7.2
78
402
K08.80
ICD-10 Finland
Toothache NOS
1.4
7.2
263
1859
A12AA06
ATC
calcium lactate gluconate; oral
20.1
7.1
10
5
XF404
NOMESCO Finland
Ambulatory ECG
1.5
7.1
239
1662
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
7.1
364
2729
J01MA12
ATC
levofloxacin; systemic
1.3
7.1
519
4103
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.4
7.1
325
2393
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
1.9
7.1
90
490
A01AB09
ATC
miconazole; local oral
1.4
7.0
260
1841
A91
ICPC
Abnormal result investigation NOS
1.6
7.0
165
1062
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
3.6
7.0
22
61
M70.6
ICD-10 Finland
Trochanteric bursitis
1.3
7.0
496
3902
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
7.0
712
5869
A09
ICPC
Sweating problem
2.4
7.0
45
188
JN3AE, ,
SPAT
1.7
7.0
111
646
G50.1
ICD-10 Finland
Atypical facial pain
2.1
7.0
63
304
RK320, ,
NOMESCO Finland
3.2
7.0
26
81
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.4
7.0
252
1778
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
7.0
1330
11735
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.3
6.9
552
4412
R04
ICPC
Breathing problem other
1.7
6.9
114
670
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
6.9
315
2315
J39.2
ICD-10 Finland
Other diseases of pharynx
2.7
6.9
35
130
Z02.7
ICD-10 Finland
Issue of medical certificate
1.5
6.9
204
1383
J46
ICD-10 Finland
Status asthmaticus
1.8
6.9
90
494
L05
ICPC
Flank/axilla symptom/complaint
1.5
6.9
190
1269
KAD00
NOMESCO Finland
Partial nephrectomy
4.0
6.9
19
48
A10BA02
ATC
metformin; oral
1.3
6.9
779
6503
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
2.1
6.8
58
273
P03
ICPC
Feeling depressed
1.5
6.8
244
1717
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
2.5
6.8
42
172
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
3.3
6.8
25
77
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
3.3
6.8
24
72
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
8.3
6.8
14
17
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.5
6.8
200
1354
ZX120
NOMESCO Finland
Intravenous
1.4
6.8
263
1879
C08CA13
ATC
lercanidipine; oral
1.3
6.7
456
3564
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
2.0
6.7
69
349
T15
ICPC
THYROID LUMP/MASS
16.7
6.7
10
6
C10AX09
ATC
ezetimibe; oral
1.3
6.7
472
3708
E21.0
ICD-10 Finland
Primary hyperparathyroidism
2.0
6.7
71
363
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.5
6.7
208
1423
XW000
NOMESCO Finland
Bone marrow biopsy
1.7
6.7
108
631
R25.1
ICD-10 Finland
Tremor, unspecified
1.8
6.7
89
491
SFA30
NOMESCO Finland
Three-surface restoration
1.2
6.7
1286
11339
K29
ICPC
Cardiovascular sympt/complt other
1.7
6.7
125
761
F51.0
ICD-10 Finland
Nonorganic insomnia
1.3
6.7
480
3783
F01
ICPC
Eye pain
1.8
6.7
89
492
N06AB04
ATC
citalopram; systemic
1.3
6.7
620
5054
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
6.7
314
2322
WX320
NOMESCO Finland
Spinalanesthesy
1.3
6.7
776
6496
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.5
6.7
206
1410
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.0
6.7
67
337
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
1.7
6.6
127
778
R31
ICD-10 Finland
Unspecified haematuria
1.5
6.6
227
1585
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.4
6.6
314
2324
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
1.9
6.6
73
380
N06AX16
ATC
venlafaxine; oral
1.3
6.6
387
2965
K44
ICD-10 Finland
Diaphragmatic hernia
2.7
6.6
34
128
J01
ICD-10 Finland
Acute sinusitis
1.6
6.5
156
1009
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
6.5
264
1901
UDQ02
NOMESCO Finland
Direct laryngoscopy
3.0
6.5
28
95
8000/0-C70.0
ICD-O-3
Neoplasm, benign of cerebral meninges
3.8
6.5
19
50
F13
ICPC
Eye sensation abnormal
1.8
6.5
87
482
SPAT1283
SPAT
Restricted health certificate
1.3
6.5
378
2891
K59.1
ICD-10 Finland
Functional diarrhoea
1.5
6.5
170
1124
UJF30
NOMESCO Finland
Ileoscopy through colon
1.4
6.5
313
2326
D03
ICPC
Heartburn
1.6
6.4
125
769
L11
ICPC
Wrist symptom/complaint
1.4
6.4
286
2095
E03.1
ICD-10 Finland
Congenital hypothyroidism without goitre
70.0
6.4
7
*
E01.1
ICD-10 Finland
Iodine-deficiency-related multinodular (endemic) goitre
70.0
6.4
7
*
P01BA02
ATC
hydroxychloroquine; oral
1.4
6.4
269
1952
WZC00, ,
SPAT
1.3
6.4
430
3359
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
2.6
6.4
34
130
N95.0
ICD-10 Finland
Postmenopausal bleeding
1.4
6.4
345
2609
K04
ICPC
Palpitations/awareness of heart
1.5
6.4
166
1096
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.1
6.4
56
268
D11
ICPC
Diarrhoea
1.4
6.4
330
2479
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
1.6
6.4
140
889
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.3
6.3
370
2830
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
1.5
6.3
175
1171
GD6AD
NOMESCO Finland
CT of chest and neck
5.2
6.3
18
35
R04.2
ICD-10 Finland
Haemoptysis
1.8
6.3
85
472
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
1.8
6.3
88
494
L72.1
ICD-10 Finland
Trichilemmal cyst
1.5
6.3
187
1270
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.6
6.3
132
829
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
1.8
6.3
96
554
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
1.8
6.3
91
517
ZSB00
NOMESCO Finland
Procedure related to previous procedure classified in chapter B
18.0
6.3
9
5
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
+∞
6.3
6
*
C73.94
ICD-10 Finland
Medullary thyroid carcinoma (thyroid)
+∞
6.3
6
*
E20
ICD-10 Finland
Hypoparathyroidism
+∞
6.3
6
*
2400A
ICD-9 Finland
Simple and unspecified goitre, Goitre, specified as simple
+∞
6.3
6
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
2.2
6.2
51
237
E07
ICD-10 Finland
Other disorders of thyroid
26.7
6.2
8
*
EBA00
NOMESCO Finland
Extraction of tooth
1.2
6.2
1010
8748
R06AE09
ATC
levocetirizine; oral
1.3
6.2
398
3087
H81
ICPC
Excessive ear wax
1.3
6.2
505
4046
C01CA24
ATC
epinephrine; parenteral
1.5
6.2
172
1152
H53.2
ICD-10 Finland
Diplopia
1.8
6.2
87
490
D24
ICD-10 Finland
Benign neoplasm of breast
1.9
6.2
69
361
GX1E5, ,
SPAT
2.3
6.1
42
181
NA1BA, ,
SPAT
2.9
6.1
27
93
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.6
6.1
150
977
M50.3
ICD-10 Finland
Other cervical disc degeneration
1.9
6.1
72
383
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
2.1
6.1
56
273
I50.9
ICD-10 Finland
Heart failure, unspecified
1.3
6.1
366
2813
ZYC05, ,
SPAT
1.8
6.1
79
434
N05BA01
ATC
diazepam; systemic, rectal
1.3
6.1
370
2849
G43.9
ICD-10 Finland
Migraine, unspecified
1.5
6.1
156
1028
A03CA02
ATC
clidinium and psycholeptics; oral
1.5
6.0
173
1166
D29
ICPC
Digestive symptom/complaint other
1.9
6.0
75
406
L16
ICPC
Ankle symptom/complaint
1.3
6.0
365
2808

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
714
1027
8.48
307.65
3.7
1.7
4.56
4.43
pmol/l
2.85
660
910
196
83
24.96
276.24
6.1
1.2
122.22
365.82
u/ml
—
58
10
313
348
9.78
259.31
1.7
1.2
2.60
2.00
iu/l
0.72
98
86
412
734
6.23
224.79
1.3
1.2
—
—
—
0
0
3170
23796
4.55
169.57
8.3
2.9
15.36
14.50
pmol/l
66.48
3078
21629
505
1558
3.62
136.69
1.2
1.2
120.25
68.79
u/ml
2.27
152
510
1661
10161
2.21
111.55
5.2
4.0
7.40
7.40
ph
0.77
1203
7268
2346
16645
2.24
106.16
7.8
6.8
1.21
1.22
mmol/l
4.45
2171
14338
605
2591
2.61
89.78
3.2
3.6
64.18
89.61
ng/l
19.90
554
2209
2103
14833
2.05
89.22
6.8
6.1
1.21
1.22
mmol/l
5.26
2005
13672
3285
28426
3.57
77.49
10.1
4.1
1.64
1.93
mu/l
8.18
3181
26132
1535
10488
1.83
63.29
2.2
2.4
—
—
—
0
0
1810
13497
1.71
51.08
2.4
2.2
—
—
—
0
0
983
6292
1.78
47.20
4.0
3.8
110.38
310.46
ng/l
4.50
702
4890
1619
11916
1.67
46.36
3.4
3.6
2.35
2.37
mmol/l
5.94
1488
10772
1196
8178
1.70
44.93
4.0
3.9
92.30
91.97
%
0.17
1178
7995
1172
7971
1.71
44.91
2.3
2.3
—
—
—
0
0
2754
23545
1.80
42.79
5.2
4.6
12.11
13.08
mm/h
3.62
2648
21974
1964
15397
1.63
42.17
2.8
2.5
78.42
79.85
nmol/l
1.56
1834
13913
1907
14923
1.61
40.57
2.7
2.8
—
—
estimate
—
0
0
2863
25007
1.80
38.23
25.6
20.9
329.97
330.82
g/l
5.96
2856
24877
871
5690
1.71
37.47
3.4
2.8
1.11
1.89
e6/l
0.77
423
2973
1408
10399
1.59
37.06
3.9
3.3
83.26
61.44
e6/l
0.19
1036
7796
796
5098
1.73
36.71
3.5
2.9
4.27
3.52
e6/l
0.54
344
2376
1575
11985
1.57
36.16
4.9
3.9
84.78
109.39
e6/l
0.56
1073
8193
1143
8076
1.62
35.94
4.2
4.0
0.00
0.78
—
5
87
2207
18207
1.58
34.92
9.6
9.9
4.04
4.06
e9/l
0.15
1879
15721
2802
24508
1.72
34.90
8.8
8.3
78.64
79.72
u/l
0.75
2710
23194
998
7025
1.59
30.92
3.0
3.0
2.44
2.46
mmol/l
5.41
880
6340
1249
9256
1.54
30.81
3.3
3.2
0.00
0.06
2.57
11
241
1842
14838
1.51
30.57
4.8
4.8
36.23
35.55
g/l
7.04
1764
13900
1222
9025
1.54
30.55
3.8
3.2
0.29
0.45
e6/l
3.19
848
6508
255
1182
2.25
30.31
2.2
1.3
—
—
—
0
0
2204
18498
1.52
29.57
5.0
4.7
6.59
6.62
mmol/l
0.23
2126
17547
2007
16555
1.50
29.00
6.8
6.5
0.19
0.19
e9/l
0.20
1740
14336
1955
16065
1.49
28.60
6.6
6.3
0.04
0.04
e9/l
0.01
1641
13656
1950
16022
1.49
28.50
6.6
6.3
0.56
0.57
e9/l
0.66
1636
13615
3252
30179
2.11
28.21
19.4
16.1
22.89
23.89
mg/l
0.99
2787
24831
1979
16340
1.49
28.00
6.7
6.3
1.90
1.89
e9/l
0.24
1716
14253
3317
31071
2.31
27.24
22.0
18.8
139.97
139.71
mmol/l
8.13
3296
30505
851
5925
1.58
27.02
1.4
1.3
17.11
11.46
u/ml
1.00
310
2245
3319
31130
2.30
26.61
22.4
18.9
3.93
3.96
mmol/l
6.43
3296
30489
1838
15066
1.46
26.22
6.8
6.5
28.11
27.72
%
0.84
1762
14232
1785
14570
1.46
25.90
3.3
3.0
100.91
116.10
ug/l
3.48
1693
13578
1806
14793
1.46
25.61
6.7
6.4
57.07
57.46
%
0.74
1745
14081
1291
9931
1.48
25.28
6.6
6.3
—
—
—
0
0
513
3196
1.71
25.22
2.7
2.4
43.37
40.97
u/l
0.12
424
2676
1799
14756
1.45
25.12
6.8
6.5
2.80
2.78
%
0.12
1713
13772
1798
14790
1.44
24.46
6.9
6.6
8.61
8.76
%
1.44
1711
13812
1795
14774
1.44
24.26
6.9
6.6
0.70
0.69
%
0.33
1707
13767
2036
17155
1.45
24.23
6.1
6.5
10.87
11.00
umol/l
0.24
1970
16371
658
4420
1.60
23.98
1.3
1.3
—
—
—
0
0
686
4656
1.59
23.93
1.3
1.2
—
—
—
0
0
2427
21192
1.47
23.59
5.8
5.0
10723.75
2565.49
e6/l
0.68
16
279
881
6342
1.52
23.55
1.4
1.3
32.56
31.64
iu/ml
0.08
257
1999
975
7206
1.49
22.83
2.8
2.7
6.27
6.66
e6/l
0.30
884
6532
1277
10045
1.43
21.19
2.2
2.1
156.15
196.80
u/l
1.60
1223
9487
953
7161
1.45
20.02
1.9
1.7
1.14
1.20
mg/l
0.22
760
5608
1744
14657
1.38
18.87
15.6
14.3
1.25
1.23
inr
0.52
1426
12099
1735
14589
1.38
18.60
2.3
2.1
97.82
97.43
pmol/l
0.13
878
7190
742
5381
1.48
18.50
3.0
3.2
0.81
0.81
mmol/l
0.70
708
5063
3355
32079
2.13
17.74
25.2
21.1
73.79
73.03
umol/l
0.67
3339
31698
3144
29505
1.65
17.41
5.6
5.2
5.94
5.88
mmol/l
2.33
2968
27017
646
4622
1.49
17.08
1.5
1.4
535.95
561.76
titre
0.13
158
1069
134
607
2.26
16.85
1.7
1.8
5.37
5.00
mmol/24h
0.52
124
532
3325
31820
1.91
15.53
13.9
12.4
24.00
24.21
u/l
0.34
3282
30879
1610
13628
1.34
15.37
3.9
3.7
6.25
6.26
ph
0.12
847
7505
542
3835
1.49
14.97
2.3
2.7
6.29
8.36
umol/l
2.44
464
3356
427
2875
1.55
14.90
2.4
2.0
388.95
384.27
nmol/l
0.17
401
2659
1197
9731
1.35
14.85
2.9
3.0
1046.14
1274.48
ng/l
1.38
1062
8445
3059
28742
1.51
14.38
6.9
6.2
39.50
39.03
mmol/mol
1.77
2936
26762
1971
17271
1.32
14.37
4.5
4.2
0.02
0.10
estimate
0.45
259
3373
1281
10573
1.33
14.18
3.2
3.3
28.84
32.82
u/l
2.88
1225
9976
825
6375
1.38
13.96
1.6
1.5
2.17
2.39
g/l
3.61
453
3773
995
7930
1.36
13.85
2.7
2.6
329.70
329.50
umol/l
0.02
907
6947
3204
30487
1.61
13.42
6.4
5.9
2.76
2.76
mmol/l
0.09
3053
28225
568
4144
1.44
13.28
4.6
5.3
1.02
1.04
mmol/l
0.57
528
3815
393
2664
1.54
13.24
6.9
8.2
—
—
—
0
0
1923
16905
1.31
13.13
4.5
4.2
0.00
0.00
estimate
1.08
263
3398
413
2845
1.51
12.90
5.7
6.8
1.25
1.29
mmol/l
0.24
406
2795
562
4153
1.42
12.17
2.2
2.3
116.94
117.38
ug/g
0.01
471
3269
1932
17124
1.29
11.79
4.5
4.2
5.12
3.89
estimate
0.09
274
3543
515
3792
1.42
11.33
1.3
1.4
—
—
—
0
0
3368
32640
1.86
11.04
29.5
24.5
257.72
257.63
e9/l
0.03
3306
31965
3368
32642
1.86
11.00
29.4
24.5
90.96
91.35
fl
5.73
3359
32292
3368
32644
1.86
10.97
29.4
24.4
30.08
30.28
pg
9.53
3358
32293
3368
32645
1.86
10.96
30.0
24.9
40.17
39.90
%
0.73
3358
32275
3368
32646
1.86
10.94
29.5
24.6
6.73
6.65
e9/l
0.82
3287
31844
3368
32646
1.86
10.94
29.5
24.5
4.46
4.40
e12/l
10.53
3287
31851
3368
32653
1.85
10.83
29.7
24.7
132.95
132.29
g/l
2.22
3358
32310
915
7435
1.31
10.64
1.4
1.3
1.10
1.55
u/ml
1.32
193
1913
129
687
1.91
10.64
2.0
1.5
286.39
294.23
mu/l
0.11
121
632
1214
10244
1.28
10.58
3.0
2.6
55.55
69.52
u/l
1.11
1148
9494
368
2579
1.48
10.51
2.3
2.4
0.33
0.48
e6/l
1.15
351
2458
1004
8284
1.30
10.37
2.3
2.4
2.69
2.86
mg/l
1.38
862
7167
2685
25029
1.31
10.16
24.2
19.9
13.74
13.68
%
1.82
2663
24711
1312
11236
1.27
9.98
3.5
3.4
—
—
—
0
0
75
336
2.26
9.83
1.5
1.4
30.75
22.09
ng/l
0.63
75
336
300
2050
1.51
9.69
7.3
8.9
94.32
94.06
%
0.30
300
2040
1257
10740
1.27
9.67
3.4
3.3
6.70
6.77
mmol/l
0.22
1087
8974
674
5351
1.32
9.08
2.7
2.5
13.10
12.65
umol/l
0.97
647
4969
360
2596
1.43
8.82
3.0
2.9
153.46
186.23
ng/l
1.62
327
2372
432
3217
1.39
8.81
6.7
7.4
96.11
95.65
%
0.91
419
3103
373
2711
1.42
8.75
1.2
1.2
—
—
—
0
0
3130
30008
1.41
8.72
5.4
5.1
4.72
4.77
mmol/l
2.17
3007
27921
177
1104
1.64
8.53
1.8
1.7
—
—
—
0
0
483
3681
1.36
8.53
6.4
7.1
12.90
12.51
kpa
0.77
469
3531
312
2206
1.45
8.50
2.3
2.4
25.62
22.40
au/ml
0.25
44
216
483
3684
1.36
8.48
6.5
7.1
5.23
5.11
kpa
2.00
470
3533
408
3032
1.39
8.41
7.0
7.8
119.21
119.08
g/l
0.05
403
2952
60
263
2.30
8.33
1.3
1.2
—
—
—
0
0
478
3651
1.36
8.31
6.4
7.0
0.90
1.08
mmol/l
0.50
412
3018
480
3673
1.36
8.25
6.6
7.1
7.41
7.42
ph
0.69
223
1983
92
482
1.93
8.05
1.4
1.3
59.41
47.25
mu/l
0.39
83
433
222
1481
1.53
8.05
1.4
1.3
35.04
34.51
iu/l
0.07
196
1294
3108
29831
1.38
7.96
5.2
5.0
1.50
1.56
mmol/l
14.24
2954
27549
285
3965
0.69
7.94
5.0
5.0
33.86
33.29
%
0.44
217
2531
86
443
1.97
7.91
1.5
1.3
0.27
0.19
nmol/l
0.54
67
355
285
2017
1.45
7.73
1.3
1.3
55.17
52.13
au/ml
0.08
17
132
1194
10337
1.24
7.72
3.4
3.3
32.01
41.52
mg/l
1.35
761
6127
1210
10496
1.23
7.67
3.9
4.0
6.14
8.25
mg/mmol
1.27
724
6069
895
7513
1.26
7.63
4.7
4.4
1.02
1.22
kg/l
0.50
609
5004
55
242
2.29
7.60
1.3
1.2
—
—
—
0
0
288
2051
1.44
7.56
1.3
1.3
95.40
199.68
u/ml
7.13
273
1908
359
2664
1.39
7.46
3.2
2.7
6.03
6.08
ph
0.45
252
1829
201
1337
1.53
7.40
2.4
2.4
2.93
2.94
g/l
0.05
187
1209
147
910
1.64
7.34
3.4
3.3
1.85
2.05
index
0.17
60
456
185
1211
1.56
7.33
2.4
2.4
9.56
10.17
g/l
1.38
169
1071
340
2511
1.39
7.27
2.4
2.4
6.04
6.42
ug/l
0.14
310
2186
1555
13896
1.21
7.23
11.3
11.4
0.00
0.00
e9/l
0.28
1176
11227
616
4997
1.28
6.90
2.7
2.5
2.37
2.34
g/l
1.01
589
4596
85
464
1.85
6.64
1.3
1.3
589.22
310.87
pmol/l
0.45
76
396
43
181
2.39
6.61
1.3
1.5
81.42
75.52
umol/l
0.56
43
181
2167
20100
1.21
6.49
3.3
3.3
43.11
46.48
u/l
0.92
2078
18757
569
4606
1.28
6.46
2.7
2.5
21.63
21.75
%
0.08
545
4264
591
4815
1.27
6.36
2.2
1.9
29.06
29.33
s
0.59
576
4675
92
522
1.78
6.35
1.6
1.3
0.43
0.35
nmol/l
—
7
34
142
905
1.59
6.35
1.2
1.2
—
—
—
0
0
205
1416
1.48
6.34
2.3
2.3
4.21
4.23
g/l
0.10
191
1287
205
1417
1.47
6.32
2.3
2.3
7.31
7.50
g/l
1.01
191
1289
205
1417
1.47
6.32
2.3
2.3
3.50
3.71
g/l
2.07
190
1289
185
1259
1.50
6.17
1.1
1.1
—
—
—
0
0
76
416
1.85
5.92
1.4
1.3
—
—
nmol/l
—
0
0
121
764
1.60
5.66
1.3
1.3
68.88
45.30
u/ml
0.76
16
95
1088
9568
1.20
5.60
1.7
1.7
20.43
20.89
nmol/l
0.43
981
7958
988
11236
0.83
5.53
3.0
3.1
—
—
—
0
0
141
932
1.53
5.43
2.2
2.1
10.75
11.70
nmol/l
0.71
128
823
179
1246
1.46
5.37
1.7
1.6
14.23
17.11
u/ml
0.27
27
261
2953
28422
1.25
5.34
4.5
4.2
1.30
1.25
mmol/l
4.02
2782
25966
964
8445
1.20
5.09
1.4
1.4
—
—
—
0
0
987
8667
1.19
5.07
4.3
4.3
—
—
—
0
0
704
6000
1.22
4.96
3.1
2.9
516.29
509.40
mosm/kgh2o
0.39
603
5208
149
1020
1.48
4.89
1.3
1.3
75.09
37.48
u/ml
—
7
58
450
3666
1.26
4.81
1.7
1.8
—
—
—
0
0
478
3922
1.25
4.80
1.5
1.5
—
—
—
0
0
115
754
1.54
4.65
1.2
1.1
—
—
—
0
0
179
2451
0.72
4.55
4.9
4.2
—
—
—
0
0
209
1544
1.38
4.53
1.3
1.2
—
—
—
0
0
142
982
1.46
4.46
2.5
2.5
—
—
—
0
0
48
250
1.93
4.44
1.6
1.5
76.83
97.52
ng/l
1.84
48
250
35
162
2.17
4.43
2.3
2.8
610.97
932.15
u/ml
1.82
35
162
22
82
2.69
4.41
1.3
1.2
9.83
11.22
pmol/l
—
10
33
389
3153
1.26
4.34
4.1
4.2
7.37
7.36
ph
0.73
325
2181
150
1057
1.44
4.28
1.4
1.4
324.49
281.64
ug/g
1.90
88
615
145
1019
1.44
4.21
1.7
1.8
1.23
1.19
g/l
0.95
140
973
185
1360
1.38
4.16
1.3
1.3
0.18
1.54
u/ml
2.71
20
116
47
250
1.89
4.11
1.9
1.5
2090.79
1794.27
ml
1.50
47
244
769
6717
1.19
4.09
4.6
4.8
—
—
—
0
0
144
1017
1.43
4.08
1.1
1.1
—
—
—
0
0
233
1787
1.33
3.99
3.0
3.8
24.99
24.38
mmol/l
2.51
233
1768
75
462
1.64
3.99
1.2
1.2
16.03
15.63
u/l
0.05
60
373
227
1740
1.33
3.91
2.1
2.0
—
—
—
0
0
232
1787
1.32
3.86
2.4
2.4
—
—
—
0
0
1300
11897
1.15
3.71
3.8
3.8
47.27
87.89
ng/l
0.50
868
8342
185
1398
1.34
3.54
1.7
2.0
9.62
7.05
iu/ml
0.52
44
358
14
46
3.05
3.52
1.2
1.1
0.05
10.71
u/ml
0.49
14
46
76
488
1.57
3.46
1.3
1.3
—
—
—
0
0
375
3116
1.23
3.38
1.3
1.4
—
—
—
0
0
50
290
1.73
3.37
1.2
1.2
109.08
111.36
pmol/l
0.11
50
290
132
953
1.40
3.37
1.3
1.3
1.68
5.80
u/ml
—
9
104
132
954
1.40
3.35
1.4
1.3
2.28
6.55
u/ml
1.86
17
163
13
38
3.43
3.30
4.2
1.6
26.03
62.60
pmol/l
0.72
13
33
55
332
1.67
3.22
3.5
3.4
14.79
12.88
index
0.42
24
179
361
3004
1.22
3.21
3.3
3.6
2.14
1.97
mmol/l
0.40
332
2656
41
228
1.81
3.20
1.3
1.1
—
76.25
—
0
8
41
228
1.81
3.20
1.3
1.1
140.00
101.43
titre
—
8
35
117
838
1.41
3.14
1.1
1.1
—
—
—
0
0
25
119
2.11
3.04
1.4
1.4
137.78
75.67
nmol/24h
0.42
25
119
372
3124
1.21
3.03
3.3
3.6
7.37
7.38
ph
2.52
174
1754
447
3821
1.19
3.02
3.7
4.1
27.07
24.04
ug/l
0.06
359
3088
367
3080
1.21
3.01
3.3
3.6
6.01
5.81
kpa
3.82
357
3004
92
637
1.46
2.99
1.3
1.2
—
—
—
0
0
1439
13395
1.13
2.98
2.0
1.9
1.35
1.32
mmol/l
0.72
1251
11187
155
1175
1.33
2.95
2.0
1.8
21.43
20.93
s
0.30
142
1034
77
519
1.49
2.87
1.5
1.7
—
—
—
0
0
16
361
0.44
2.86
2.1
2.5
—
—
—
0
0
78
529
1.49
2.83
2.1
1.7
—
—
—
0
0
414
3539
1.19
2.80
2.4
2.6
1.81
1.83
%
0.20
376
3157
289
2399
1.22
2.67
1.3
1.3
—
—
—
0
0
20
92
2.18
2.67
1.5
1.3
—
—
—
0
0
314
2629
1.21
2.66
5.9
6.9
9.01
9.76
mmol/l
1.13
295
2529
7
15
4.67
2.59
2.0
3.3
25.33
24.91
mg/l
—
7
15
33
185
1.79
2.56
1.2
1.7
5.08
5.24
u/l
0.19
25
154
12
44
2.73
2.54
1.6
1.6
—
—
—
0
0
36
209
1.73
2.50
1.4
1.7
276.13
336.82
mu/l
0.90
31
167
128
975
1.32
2.42
10.0
9.3
—
—
—
0
0
246
2031
1.23
2.42
1.5
1.4
—
—
—
0
0
88
636
1.39
2.33
1.7
1.5
—
1.00
—
0
5
67
461
1.46
2.32
1.1
1.2
2.29
3.73
u/ml
1.26
24
187
10
34
2.95
2.28
1.0
1.1
1.98
1.62
umol/24h
—
10
34
8
23
3.48
2.27
2.1
2.1
0.57
0.50
ug/l
—
8
23
165
1313
1.27
2.27
2.9
3.4
858.42
3712.41
u/ml
0.72
132
1125
42
651
0.64
2.20
3.5
3.5
24.28
25.86
mg/l
0.12
32
454
42
264
1.60
2.20
1.6
2.0
4.13
7.29
umol/l
2.03
32
187
323
2768
1.18
2.17
2.4
2.6
72.01
69.85
e9/l
0.55
221
2005
300
2556
1.19
2.15
1.5
1.4
—
—
—
0
0
140
1100
1.28
2.14
1.2
1.3
—
—
—
0
0
323
2774
1.18
2.12
2.3
2.7
66.09
66.32
g/l
0.24
298
2520
42
268
1.57
2.08
1.1
1.2
—
—
—
0
0
506
4509
1.14
2.05
2.1
2.0
—
—
—
0
0
10
38
2.64
2.00
1.3
1.3
—
112.38
—
0
5
484
4310
1.14
1.98
1.7
1.7
—
—
—
0
0
57
395
1.45
1.95
1.0
1.1
1.99
3.28
eliau/ml
0.62
23
160
268
2284
1.19
1.94
3.5
3.4
0.90
0.78
ug/l
0.44
195
1559
114
893
1.29
1.83
1.8
1.6
9838.41
10569.15
e6/l
0.07
74
627
53
749
0.70
1.80
3.5
4.6
—
—
—
0
0
121
958
1.27
1.79
6.0
5.5
1.32
1.26
mmol/l
0.33
115
843
218
1840
1.20
1.78
4.5
4.6
—
—
—
0
0
17
88
1.94
1.74
1.1
1.2
27.41
27.73
s
0.10
17
88
33
209
1.58
1.73
1.1
1.2
14.43
16.55
u/ml
—
7
90
197
1654
1.20
1.71
1.2
1.2
—
—
—
0
0
66
483
1.37
1.70
1.1
1.1
1.80
3.60
u/ml
1.49
35
240
27
164
1.65
1.67
2.6
1.2
155.22
283.40
u/l
1.09
27
145
95
738
1.30
1.65
2.0
2.0
8134.20
5210.91
u/l
0.27
31
302
27
166
1.63
1.61
1.1
1.0
0.42
0.79
u/ml
0.40
14
60
1331
12642
1.09
1.58
4.4
4.1
0.51
0.44
estimate
0.04
207
2751
25
152
1.65
1.56
2.5
1.6
—
—
—
0
0
58
423
1.38
1.55
1.2
1.2
—
—
—
0
0
35
517
0.67
1.54
1.1
1.2
—
—
—
0
0
174
1462
1.20
1.53
1.6
1.7
1.54
1.59
g/l
0.36
159
1266
26
161
1.62
1.52
1.6
1.6
7.12
4.33
nmol/l
0.24
20
132
448
4043
1.12
1.52
3.3
3.2
4.66
4.57
e9/l
0.10
416
3470
106
846
1.26
1.52
1.9
2.0
11.71
12.35
mg/l
0.43
98
781
31
201
1.55
1.51
1.1
1.1
3.56
14.92
nmol/l
—
8
33
241
2772
0.86
1.49
5.4
4.5
0.10
0.12
%
0.23
72
747
61
453
1.35
1.48
1.2
1.1
—
—
—
0
0
75
576
1.31
1.45
1.1
1.1
0.64
1.85
u/ml
2.10
45
305
27
412
0.65
1.42
3.1
2.1
1.09
0.91
%
0.42
18
271
359
3212
1.13
1.41
2.1
2.2
0.21
0.21
g/l
1.05
345
3025
38
262
1.46
1.41
1.1
1.2
—
—
—
0
0
284
2505
1.15
1.39
2.1
4.2
71.38
69.13
u/ml
0.02
278
2417
64
484
1.33
1.39
1.3
1.2
26.48
34.09
u/l
0.36
58
413
98
785
1.26
1.38
1.3
1.2
—
—
—
0
0
37
255
1.46
1.38
3.1
2.6
30.95
25.73
mg/l
0.11
28
174
12
60
2.00
1.38
1.2
1.2
153.54
142.82
pmol/l
0.14
12
60
112
917
1.23
1.31
1.3
1.2
434.00
813.53
titre
—
5
34
17
98
1.74
1.31
1.4
1.5
81.72
118.00
nmol/l
—
8
67
6
24
2.50
1.30
1.5
1.2
—
—
—
0
0
8
35
2.29
1.26
2.3
1.3
—
—
—
0
0
69
538
1.29
1.24
1.2
1.1
27.16
20.47
au/ml
0.20
13
117
46
339
1.36
1.21
1.5
1.4
18326.00
41096.06
e6/l
0.67
22
171
578
5359
1.09
1.20
1.7
1.7
1063.44
1187.41
nmol/l
2.61
474
4034
59
453
1.31
1.19
1.2
1.1
—
—
—
0
0
258
2894
0.88
1.16
5.3
4.5
1.02
0.86
%
0.34
88
864
425
3891
1.11
1.15
6.2
5.8
2.13
3.18
ug/l
2.25
388
3474
245
2754
0.88
1.14
5.2
4.3
0.70
0.64
%
0.14
89
823
50
378
1.33
1.13
3.5
3.4
3.84
20.66
nmol/l
0.60
50
363
72
573
1.26
1.12
2.0
2.3
162.95
75.08
ug/min
0.42
42
321
337
3055
1.11
1.11
1.6
1.5
—
—
—
0
0
7
31
2.26
1.10
1.0
1.1
0.51
9.14
u/ml
—
7
31
7
31
2.26
1.10
1.3
1.3
5.67
5.85
mmol/l
—
7
31
51
389
1.32
1.10
1.4
1.4
2075.50
1980.00
e6/l
0.05
34
261
85
694
1.23
1.07
1.5
1.4
1411.32
1361.72
e6/l
0.02
63
540
267
2394
1.12
1.07
2.8
2.9
10.04
10.40
g/l
0.83
253
2207
44
330
1.34
1.07
2.1
2.2
—
—
—
0
0
140
1627
0.85
1.06
2.3
2.3
0.00
0.51
estimate
0.50
51
490
51
657
0.77
1.05
2.8
3.3
57.73
58.60
%
0.17
51
657
83
680
1.23
1.02
1.3
1.4
9.33
35.28
e6/l
1.45
57
495
236
2637
0.89
1.02
5.2
3.6
1.22
1.24
mmol/l
2.50
207
2274
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
21
140
1.50
0.97
1.1
1.0
0.18
0.30
u/ml
—
6
36
34
250
1.36
0.95
1.2
1.1
5.83
6.99
iu/ml
—
7
64
0
32
0.00
0.95
0.0
1.7
—
0.44
—
0
32
253
2800
0.90
0.94
5.5
4.7
0.89
0.44
%
0.32
77
703
285
2588
1.11
0.94
2.8
2.9
4.42
4.46
kpa
0.14
277
2518
71
579
1.23
0.93
1.6
1.8
—
—
—
0
0
59
471
1.26
0.93
1.1
1.1
0.92
0.99
u/ml
0.05
29
194
6
27
2.22
0.93
1.0
1.1
—
—
—
0
0
55
436
1.27
0.92
1.0
1.1
0.37
1.28
u/ml
1.55
29
210
634
6725
0.93
0.92
1.7
1.7
26182250.95
38706651.74
pmol/l
0.27
550
5565
38
287
1.33
0.91
1.3
1.1
—
—
—
0
0
35
261
1.34
0.91
1.5
1.2
0.71
1.12
u/ml
0.36
21
146
23
159
1.45
0.91
1.4
1.3
130.24
131.99
nmol/l
0.07
23
159
6
29
2.07
0.89
1.5
1.4
—
—
—
0
0
15
95
1.58
0.87
1.1
1.1
—
—
—
0
0
96
814
1.18
0.87
3.4
4.2
3.78
3.83
mmol/l
0.75
96
806
19
128
1.49
0.85
1.3
1.3
145.32
150.57
mmol/24h
0.14
19
128
13
80
1.63
0.84
1.3
1.1
—
—
—
0
0
46
362
1.27
0.84
1.2
1.2
7.11
7.20
mmol/l
0.08
41
315
8
47
1.70
0.80
1.6
1.6
—
—
—
0
0
29
385
0.75
0.79
1.6
1.6
64.07
56.49
%
0.41
14
231
189
1699
1.12
0.78
3.2
3.6
1.01
1.02
ratio
2.05
161
1542
24
327
0.73
0.78
1.2
1.1
—
—
—
0
0
48
385
1.25
0.77
1.6
1.2
—
—
—
0
0
62
512
1.21
0.76
1.1
1.6
—
14.36
—
0
14
22
157
1.40
0.76
1.0
1.0
0.48
1.73
u/ml
—
6
40
51
414
1.24
0.74
2.7
2.0
88.40
1230.78
u/ml
0.88
51
407
895
9313
0.95
0.72
5.0
4.4
0.00
0.00
estimate
1.74
248
3211
15
217
0.69
0.70
1.4
1.1
—
—
—
0
0
41
329
1.25
0.67
1.6
1.4
—
—
—
0
0
12
179
0.67
0.66
2.3
2.8
105.08
248.32
e6/l
0.47
12
171
45
367
1.23
0.65
1.3
1.4
—
—
—
0
0
209
1914
1.10
0.64
1.8
1.9
1.36
1.43
g/l
0.15
194
1754
38
305
1.25
0.63
1.4
1.4
—
—
—
0
0
10
153
0.65
0.62
1.2
1.2
—
—
—
0
0
209
1919
1.09
0.61
6.6
6.6
25.28
24.66
mmol/l
2.07
203
1824
23
173
1.33
0.61
3.7
3.5
—
—
—
0
0
5
30
1.67
0.61
1.0
1.2
108.80
89.60
titre
—
5
30
73
628
1.17
0.61
1.3
1.6
—
—
—
0
0
56
471
1.19
0.61
1.2
1.2
—
—
—
0
0
129
1156
1.12
0.60
2.7
3.2
30.35
53.73
mg/l
3.10
111
988
210
1931
1.09
0.60
2.7
3.0
128.93
127.07
g/l
0.62
202
1876
104
920
1.13
0.60
1.3
1.2
308.33
180.34
titre
—
6
88
28
218
1.29
0.60
1.0
1.1
—
—
—
0
0
63
537
1.18
0.59
1.3
1.2
342.89
276.62
u/ml
0.55
36
309
70
810
0.86
0.59
1.2
1.1
0.71
0.61
ratio
0.54
11
129
109
970
1.13
0.58
3.6
3.2
7.41
7.41
ph
0.34
109
961
204
2213
0.92
0.58
1.3
1.3
—
—
—
0
0
7
115
0.61
0.57
1.6
1.1
—
—
—
0
0
72
624
1.16
0.56
1.3
1.6
—
—
—
0
0
73
634
1.15
0.56
1.3
1.6
—
—
—
0
0
29
362
0.80
0.55
1.7
1.4
276.38
274.59
mosm/kgh2o
0.12
21
272
47
394
1.20
0.54
1.7
1.4
—
—
—
0
0
47
394
1.20
0.54
1.7
1.4
—
—
—
0
0
47
394
1.20
0.54
1.7
1.4
—
—
—
0
0
47
394
1.20
0.54
1.7
1.4
—
—
—
0
0
6
38
1.58
0.54
2.5
3.1
—
—
—
0
0
92
815
1.13
0.54
1.0
1.1
3.38
9.90
eliau/ml
0.89
11
82
124
1119
1.11
0.53
2.3
2.1
558.19
770.57
ug/l
0.31
117
1058
72
628
1.15
0.53
1.3
1.6
—
—
—
0
0
6
39
1.54
0.53
1.5
1.7
—
—
—
0
0
6
39
1.54
0.53
1.2
1.1
—
—
—
0
0
128
1159
1.11
0.52
2.7
3.2
22.60
49.85
mg/l
2.04
109
992
6
97
0.62
0.52
1.2
1.4
60.17
67.61
%
—
6
80
210
1948
1.08
0.52
3.3
3.6
5.23
5.18
kpa
0.43
204
1864
47
397
1.19
0.51
1.3
1.3
33.98
34.54
u/l
0.04
42
332
33
269
1.23
0.51
1.2
1.2
—
—
—
0
0
32
260
1.23
0.51
2.4
2.6
16.69
30.13
mg/l
2.58
26
181
24
189
1.27
0.49
1.1
1.3
—
—
—
0
0
50
427
1.17
0.49
7.5
5.9
13.31
12.56
mg/l
0.60
41
399
7
45
1.56
0.49
1.1
1.2
66.71
65.93
ug/l
—
7
45
415
3952
1.06
0.48
1.7
1.5
—
—
—
0
0
347
3289
1.06
0.48
2.4
2.2
0.00
0.01
estimate
0.69
57
634
66
578
1.14
0.47
1.3
1.6
—
—
—
0
0
7
47
1.49
0.47
1.1
1.1
0.47
1.19
u/ml
—
7
40
78
876
0.89
0.46
2.9
3.1
1.51
1.54
mg/l
0.13
72
797
5
81
0.62
0.45
7.4
3.2
10.93
7.83
mg/l
—
5
68
11
77
1.43
0.45
1.8
2.0
9.81
10.07
mg/l
0.04
11
65
20
156
1.28
0.45
1.1
1.0
—
—
—
0
0
10
69
1.45
0.44
2.6
2.0
—
—
—
0
0
40
339
1.18
0.44
1.5
1.5
—
—
—
0
0
93
1030
0.90
0.44
3.7
3.8
24.98
25.13
mmol/l
0.22
88
938
17
219
0.78
0.43
1.6
2.0
17.76
16.26
%
0.22
17
213
18
230
0.78
0.43
2.0
2.0
66.00
72.66
%
1.12
18
218
20
157
1.28
0.43
2.5
3.7
—
—
—
0
0
5
31
1.61
0.43
3.8
2.9
0.40
0.90
u/field
—
5
31
28
230
1.22
0.42
1.4
1.2
—
—
—
0
0
23
185
1.24
0.41
1.1
1.1
—
—
—
0
0
32
381
0.84
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
46
398
1.16
0.40
1.0
1.1
0.85
2.71
u/ml
1.86
23
183
0
17
0.00
0.40
0.0
1.5
—
308.65
—
0
17
13
172
0.75
0.40
1.3
2.3
6.74
7.92
mmol/l
1.78
13
172
114
1046
1.09
0.39
1.4
1.6
0.25
0.33
mg/l
0.88
39
470
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
40
344
1.16
0.38
1.1
1.0
0.04
0.20
u/ml
1.67
15
117
36
420
0.86
0.38
2.2
3.0
—
—
—
0
0
25
206
1.22
0.37
1.2
1.4
12.08
12.73
u/l
0.28
25
196
9
68
1.32
0.37
1.2
1.0
13.32
29.54
iu/ml
—
9
68
28
332
0.84
0.36
2.7
2.5
—
—
—
0
0
39
337
1.16
0.36
1.5
1.5
1.24
1.26
mm
0.20
23
228
31
364
0.85
0.36
1.3
1.2
—
—
—
0
0
9
122
0.74
0.35
18.9
13.2
900.78
831.86
nmol/l
—
9
116
111
1025
1.09
0.35
2.7
3.1
1.60
4.23
ratio
1.93
50
580
6
43
1.40
0.35
1.7
1.0
—
—
—
0
0
6
43
1.40
0.35
1.7
1.0
—
—
—
0
0
6
43
1.40
0.35
1.7
1.0
—
—
—
0
0
70
632
1.11
0.35
1.4
1.3
—
—
—
0
0
49
435
1.13
0.32
1.5
1.5
58.04
59.52
ug/l
0.09
36
347
77
702
1.10
0.32
3.4
3.3
0.79
0.80
nmol/l
0.01
65
581
20
164
1.22
0.32
1.8
2.5
44.90
41.21
%
—
10
90
12
153
0.78
0.30
2.5
2.9
—
—
—
0
0
10
130
0.77
0.29
2.5
2.2
29.40
29.03
%
—
10
130
79
728
1.09
0.28
3.4
3.1
60.61
740.96
u/ml
1.20
70
658
19
158
1.20
0.28
1.8
1.8
0.92
2.27
u/field
1.58
13
103
12
94
1.28
0.28
1.2
1.1
—
—
—
0
0
8
65
1.23
0.27
1.1
1.4
31.50
20.98
%
—
8
52
23
268
0.86
0.26
1.1
1.3
—
—
—
0
0
123
1158
1.06
0.26
1.3
1.4
—
—
—
0
0
91
848
1.08
0.26
1.4
1.3
152.61
226.38
miu/ml
1.24
28
403
60
549
1.09
0.25
2.4
2.0
0.84
0.83
nmol/l
0.04
53
464
24
277
0.87
0.25
1.9
1.5
34.66
32.61
%
0.08
12
165
46
416
1.11
0.25
1.5
1.4
0.25
0.39
nmol/l
1.39
31
302
47
518
0.91
0.24
1.1
1.1
—
—
—
0
0
81
870
0.93
0.24
1.2
1.1
1.58
1.61
g/l
0.48
81
870
30
264
1.14
0.24
1.1
1.1
—
—
—
0
0
6
81
0.74
0.24
3.0
2.4
—
—
—
0
0
39
351
1.11
0.23
1.6
1.5
—
—
—
0
0
5
39
1.28
0.23
4.8
2.8
12.68
15.05
ml/dl
—
5
33
5
39
1.28
0.23
3.8
1.8
13.68
18.58
umol/l
—
5
39
30
337
0.89
0.22
1.5
1.4
10731.13
84921.07
e6/l
1.56
16
229
10
79
1.27
0.22
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
47
430
1.09
0.21
1.3
1.3
—
—
—
0
0
35
315
1.11
0.21
1.5
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
109.00
—
0
6
70
750
0.93
0.21
1.5
1.5
982.76
1062.06
mu/l
0.37
51
597
11
89
1.24
0.21
1.1
1.3
2.14
3.31
mmol/l
1.71
11
80
53
489
1.09
0.20
1.2
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
41
374
1.10
0.20
1.0
1.1
4.80
3.86
u/ml
0.08
17
156
28
311
0.90
0.18
3.1
1.4
—
—
—
0
0
196
1893
1.04
0.18
3.3
3.6
7.41
7.42
ph
1.84
170
1580
53
569
0.93
0.17
1.6
1.3
—
—
—
0
0
7
62
1.13
0.17
1.0
1.4
—
—
—
0
0
22
247
0.89
0.17
1.0
1.1
—
—
—
0
0
73
773
0.94
0.17
1.9
2.3
121.81
126.17
g/l
0.71
56
597
15
173
0.87
0.16
1.3
2.8
0.89
0.69
e9/l
0.41
15
161
8
68
1.18
0.16
9.0
4.2
—
—
—
0
0
185
1912
0.97
0.16
1.5
1.6
—
—
—
0
0
46
428
1.08
0.16
3.1
2.6
—
—
—
0
0
54
506
1.07
0.15
2.5
1.6
0.87
0.73
g/l
0.55
45
388
8
73
1.10
0.15
1.1
1.1
—
—
—
0
0
279
2860
0.97
0.15
2.1
2.0
3.44
3.30
ratio
1.16
210
2202
34
368
0.92
0.14
1.9
2.2
0.91
1.19
g/24h
0.52
23
200
47
440
1.07
0.14
1.6
1.5
34.73
32.20
g/l
0.82
42
400
29
316
0.92
0.14
2.8
4.2
—
—
—
0
0
876
8858
0.99
0.14
3.7
3.6
0.22
0.23
estimate
0.02
207
2699
36
334
1.08
0.13
1.6
1.5
—
—
—
0
0
11
128
0.86
0.13
1.1
1.2
11.27
10.77
mm/h
0.04
11
128
29
315
0.92
0.13
3.1
1.3
3.14
2.81
g/l
0.62
24
228
29
315
0.92
0.13
3.1
1.3
6.00
6.78
g/l
1.04
24
224
29
315
0.92
0.13
3.1
1.3
0.34
0.40
g/l
0.78
24
224
18
201
0.89
0.13
1.9
2.1
2.49
2.48
ug/l
0.01
13
172
16
180
0.89
0.13
1.5
2.5
15.64
15.99
%
0.17
16
180
48
509
0.94
0.12
1.6
1.3
152.07
154.86
au/ml
0.05
14
145
11
127
0.87
0.12
37.8
31.4
108.73
108.17
ug/l
0.01
11
109
12
104
1.15
0.12
1.5
2.8
0.62
0.61
mmol/l
0.16
12
104
12
104
1.15
0.12
1.0
1.2
—
—
—
0
0
54
569
0.95
0.12
1.6
1.3
—
17.93
—
0
12
41
436
0.94
0.12
3.9
2.2
—
—
—
0
0
66
630
1.05
0.12
3.2
3.5
—
—
—
0
0
11
95
1.16
0.11
1.5
1.9
0.00
0.03
estimate
0.50
11
95
103
1065
0.97
0.11
2.5
3.1
242.05
304.35
mg/l
0.65
40
403
48
504
0.95
0.10
1.1
1.1
—
—
—
0
0
5
47
1.06
0.09
1.0
1.1
108.98
75.87
ug/l
—
5
37
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
70
675
1.04
0.09
1.4
1.3
63.40
60.30
mmol/l
0.23
53
538
7
67
1.04
0.08
1.1
1.2
—
—
—
0
0
6
70
0.86
0.07
2.3
1.8
—
—
—
0
0
56
580
0.96
0.07
4.1
3.6
3.22
2.54
mmol/l
0.78
42
410
9
84
1.07
0.07
8.6
3.9
51.28
53.66
%
—
9
79
21
224
0.94
0.06
1.0
1.0
294.19
300.51
mg/l
0.17
21
203
9
100
0.90
0.06
1.4
2.0
19.67
9.27
%
—
9
93
73
711
1.03
0.06
1.4
1.6
—
—
—
0
0
14
151
0.93
0.05
1.8
1.5
—
—
—
0
0
23
218
1.06
0.05
1.0
1.1
—
—
—
0
0
19
179
1.06
0.05
1.7
1.7
—
—
—
0
0
125
1231
1.02
0.04
1.8
1.9
3.02
1.74
ug/l
0.61
114
1091
62
606
1.02
0.04
2.0
2.8
31.20
32.50
umol/l
0.24
55
547
37
382
0.97
0.04
2.2
2.2
31.18
25.20
mg/l
0.32
17
133
26
269
0.97
0.02
1.3
1.9
—
—
—
0
0
25
242
1.03
0.02
1.9
2.4
37.70
40.62
%
0.43
25
236
34
348
0.98
0.01
1.8
1.6
—
—
—
0
0
15
157
0.96
0.01
1.1
1.2
0.73
0.53
ratio
—
10
95
27
264
1.02
0.00
1.9
2.1
2.08
1.95
u/field
0.09
12
137
10
95
1.05
0.00
1.2
1.3
6.66
7.09
mmol/l
—
10
95
34
342
0.99
0.00
1.7
1.7
—
8.00
—
0
6
23
225
1.02
0.00
1.3
1.3
2.08
2.16
mmol/l
0.17
23
208
131
1315
1.00
0.00
3.4
3.7
—
—
—
0
0
15
151
0.99
0.00
1.1
1.8
39.16
39.97
g/l
0.29
15
151
16
156
1.03
0.00
1.3
1.5
—
—
—
0
0
32
324
0.99
0.00
1.1
1.2
—
—
—
0
0
212
2121
1.00
0.00
1.8
1.7
3.45
3.50
mmol/l
0.28
136
1470
10
103
0.97
0.00
1.3
1.8
25.40
29.05
%
—
10
97
17
167
1.02
0.00
1.3
1.3
7.39
7.41
ph
—
9
113
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
54
0.93
-0.00
2.6
1.6
—
—
—
0
0
14
140
1.00
-0.00
1.3
1.4
—
72.94
—
0
18
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
49.12
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
2.00
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
2701.00
—
0
6
9
99
0.91
-0.00
1.2
1.1
—
—
—
0
0
14
140
1.00
-0.00
1.1
1.1
1425.50
1529.80
miu/ml
0.13
14
140
7
69
1.01
-0.00
1.0
1.1
—
—
—
0
0
9
92
0.98
-0.00
1.8
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
2.04
—
0
7
0
5
0.00
-0.00
0.0
5.4
—
44.80
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.1
—
342.56
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
461.00
—
0
5
9
99
0.91
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
10.8
—
11.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
-0.00
1.1
1.4
10.29
21.53
%
—
7
72
8
79
1.01
-0.00
1.9
2.7
4.13
4.72
ug/l
—
8
79
0
7
0.00
-0.00
0.0
1.7
—
10.43
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
99
0.91
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
8.0
7.4
5.74
5.35
kpa
—
5
52

Mortality – FinRegistry

Association

Association between endpoint E4_GOITRENAS and mortality.

Females

Parameter HR [95% CI] p-value
E4_GOITRENAS 1.061 [0.97, 1.17] 0.221
Birth year 0.996 [0.99, 1.0] 0.364

During the follow-up period (1.1.1998 — 31.12.2019), 2088 out of 13454 females with E4_GOITRENAS died.

Males

Parameter HR [95% CI] p-value
E4_GOITRENAS 1.154 [1.02, 1.31] 0.028
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 606 out of 2491 males with E4_GOITRENAS died.

Mortality risk

Mortality risk for people of age

years, who have E4_GOITRENAS.

N-year risk Females Males
1 0.089% 0.195%
5 0.636% 1.32%
10 1.595% 3.405%
15 3.024% 6.447%
20 5.332% 10.87%

Relationships between endpoints

Index endpoint: E4_GOITRENAS – Other and/or unspecified nontoxic goitre

GWS hits: 16

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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