Divergent concomitant strabismus

H7_DIVERGSTRAB

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H50.1
  • Hospital discharge: ICD-9 3781
  • Hospital discharge: ICD-8 37301
  • Cause of death: ICD-10 H50.1
  • Cause of death: ICD-9 3781
  • Cause of death: ICD-8 37301

2 out of 7 registries used, show all original rules.

3558

4. Check minimum number of events

None

3558

5. Include endpoints

None

3558

6. Filter based on genotype QC (FinnGen only)

3187

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H50
Name in latin
Strabismus divergens concomitans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 30557 17266 13194
Only index persons 27598 15794 11804
Unadjusted period prevalence (%)
Whole population 0.44 0.49 0.37
Only index persons 0.53 0.58 0.45
Median age at first event (years)
Whole population 13.93 14.80 12.62
Only index persons 13.95 14.85 12.74

-FinnGen-

Key figures

All Female Male
Number of individuals 3187 2060 1127
Unadjusted period prevalence (%) 0.66 0.73 0.52
Median age at first event (years) 21.16 18.25 26.49

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3293
Matched controls
32930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H50.52
ICD-10 Finland
Exophoria
82.0
307.7
278
37
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
307.7
1668
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
6486.2
307.7
1272
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
2974.0
307.7
527
*
3503
FHL
Single muscle retroposition
+∞
307.7
347
*
H50.31
ICD-10 Finland
Intermittent exotropia
1889.3
307.7
473
*
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
304.0
287
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
262.0
248
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
2093.2
215.9
207
*
3507
FHL
Retroposition and resection
1970.1
204.2
196
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
26.1
201.1
140
56
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
163.9
156
*
H50.2
ICD-10 Finland
Vertical strabismus
211.5
156.4
161
8
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
149.1
142
*
H53.2
ICD-10 Finland
Diplopia
7.1
126.1
196
292
H50.0
ICD-10 Finland
Convergent concomitant strabismus
631.4
124.1
122
*
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
120.6
115
*
3505
FHL
Single muscle resection
+∞
114.2
109
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
84.7
81
*
H52.0
ICD-10 Finland
Hypermetropia
8.9
83.0
104
120
H50.51
ICD-10 Finland
Esophoria
45.2
82.7
49
11
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
77.4
74
*
H50.30
ICD-10 Finland
Intermittent esotropy
755.3
75.6
74
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
71.1
68
*
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
15.3
68.3
60
40
WX140
NOMESCO Finland
Parabulbar anesthesy
3.9
68.0
207
553
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
64.7
390
1569
3504
FHL
Retroposition of two muscles
+∞
59.6
57
*
H50.9
ICD-10 Finland
Strabismus, unspecified
76.1
59.2
67
9
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
58.5
649
3405
H52.1
ICD-10 Finland
Myopia
4.9
56.0
125
262
H52.2
ICD-10 Finland
Astigmatism
7.6
55.6
79
106
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
55.4
53
*
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
193.3
55.1
57
*
XCK00
NOMESCO Finland
Perimetry
3.1
48.3
217
742
H51.1
ICD-10 Finland
Convergence insufficiency and excess
464.2
46.4
46
*
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
42.8
41
*
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
41.7
40
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
13.4
39.1
37
28
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
38.6
37
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
38.4
953
6363
3781X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALIUS]
+∞
36.5
35
*
H50.8
ICD-10 Finland
Other specified strabismus
128.1
35.7
38
*
H27.0
ICD-10 Finland
Aphakia
12.9
33.2
32
25
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.7
32.9
188
731
3508
FHL
Transposition or anteposition
+∞
32.3
31
*
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
+∞
32.3
31
*
F95
ICPC
Strabismus
60.6
31.1
36
6
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
30.2
29
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
27.7
1246
9419
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
26.1
25
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
25.8
332
1803
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.0
25.4
309
1647
H50.4
ICD-10 Finland
Other and unspecified heterotropia
+∞
25.0
24
*
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
+∞
25.0
24
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.5
24.9
32
38
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
24.0
23
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
241.7
23.7
24
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.1
23.6
249
1261
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
22.9
22
*
183
Kela drug reimbursment
Lamotrigin and topiramate
5.2
22.9
47
92
N03AG01
ATC
valproic acid; systemic, rectal
2.1
22.1
206
995
N03AX09
ATC
lamotrigine; oral
2.2
21.1
192
918
H54.5
ICD-10 Finland
Severe visual impairment, monocular
6.9
20.8
32
47
ZXA00
NOMESCO Finland
Right side
1.5
20.7
704
4959
ZXA05
NOMESCO Finland
Left side
1.6
20.6
644
4450
N05AH02
ATC
clozapine; systemic
3.2
19.9
80
257
H50.3
ICD-10 Finland
Intermittent heterotropia
+∞
19.8
19
*
H53.3
ICD-10 Finland
Other disorders of binocular vision
6.5
19.2
31
48
3519
FHL
Other measure in this category
+∞
18.8
18
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.9
18.3
259
1449
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
18.0
638
4519
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
17.7
17
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
180.9
17.5
18
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.5
17.5
106
425
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
17.1
212
1134
H47.2
ICD-10 Finland
Optic atrophy
7.2
16.9
25
35
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
63.7
16.7
19
*
N05AH03
ATC
olanzapine; systemic
1.9
16.7
216
1173
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
16.7
16
*
Z3231
NOMESCO Finland
Registered nurse
1.4
16.6
766
5701
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
16.5
441
2928
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
40.3
16.3
20
5
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
16.1
214
1173
Z3229
NOMESCO Finland
Other healthcare associate professional
1.8
16.0
230
1293
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
15.4
541
3812
N04AA02
ATC
biperiden; systemic
3.0
15.2
67
228
F20.9
ICD-10 Finland
Schizophrenia, unspecified
2.7
14.9
81
308
N05AH04
ATC
quetiapine; oral
1.5
14.9
556
3964
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.9
14.9
178
942
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
31.8
14.8
19
6
N03AF02
ATC
oxcarbazepine; oral
2.3
14.5
104
451
N05AX12
ATC
aripiprazole; systemic
2.0
14.4
148
743
ZXA10
NOMESCO Finland
Bilateral
1.5
14.3
470
3264
S01ED01
ATC
timolol; ophthalmic
2.5
14.2
85
340
N05BA09
ATC
clobazam; oral
4.7
14.0
32
69
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
13.9
606
4446
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
13.7
973
7757
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
13.7
244
1461
WX704
NOMESCO Finland
Intubation
1.7
13.6
241
1439
ZXD20
NOMESCO Finland
Day surgery
1.6
13.5
364
2418
WX002
NOMESCO Finland
Sedation and analgesia
1.5
13.4
497
3534
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.7
13.3
69
257
N03AX14
ATC
levetiracetam; systemic
2.5
13.3
85
351
H26.4
ICD-10 Finland
After-cataract
1.8
13.1
209
1213
H54.7
ICD-10 Finland
Unspecified visual loss
4.7
12.8
29
62
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
3.9
12.8
37
96
F83
ICD-10 Finland
Mixed specific developmental disorders
5.5
12.6
24
44
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
11.0
12.5
23
21
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
20.1
12.4
18
9
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
130.5
12.4
13
*
H26.02
ICD-10 Finland
Presenil cataract
2.4
12.4
80
332
N05AA02
ATC
levomepromazine; systemic
2.1
12.3
119
584
H52.4
ICD-10 Finland
Presbyopia
2.3
12.3
93
414
G40.10
ICD-10 Finland
Simple partial seizures
4.5
12.1
29
65
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
12.1
349
2353
N06AX11
ATC
mirtazapine; oral
1.3
12.0
991
8045
37405
ICD-8 Finland
Cataract, Traumatica
21.4
12.0
17
8
R62.0
ICD-10 Finland
Delayed milestone
5.0
11.9
25
50
N03AX12
ATC
[U] gabapentin; oral
1.5
11.9
434
3072
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
11.7
120
602
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
11.7
270
1729
P85
ICPC
Mental retardation
12.6
11.6
20
16
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
11.6
322
2151
N03AX11
ATC
topiramate; oral
2.3
11.5
85
375
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
120.4
11.4
12
*
N06AA09
ATC
amitriptyline; systemic
1.7
11.4
236
1470
N03AF01
ATC
carbamazepine; oral, rectal
1.9
11.4
132
693
114
Kela drug reimbursment
Glaucoma
1.8
11.3
181
1050
N05BA01
ATC
diazepam; systemic, rectal
1.5
11.2
346
2364
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
11.1
296
1958
N03AE01
ATC
clonazepam; systemic
1.8
11.1
158
885
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
4.1
11.1
30
74
AA1AD
NOMESCO Finland
CT of head and brain
1.4
10.8
694
5415
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
10.8
171
991
N06AB06
ATC
sertraline; oral
1.5
10.7
348
2403
H54.4
ICD-10 Finland
Blindness, monocular
9.6
10.7
21
22
SPAT1101
SPAT
Orthostatic test
2.2
10.6
88
408
A46
ICD-10 Finland
Erysipelas
1.5
10.5
353
2454
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
11.2
10.5
19
17
N05AX08
ATC
risperidone; systemic
1.6
10.4
217
1353
3501
FHL
Myotomy or tenotomy
+∞
10.4
10
*
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
10.4
10
*
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
10.4
10
*
3506
FHL
Resection of two muscles
+∞
10.4
10
*
3510
FHL
Cardiac surgery on three or more muscles
+∞
10.4
10
*
N05CF01
ATC
zopiclone; oral
1.3
10.4
832
6703
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
4.3
10.3
26
61
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
10.3
695
5461
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
10.3
335
2316
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
10.2
1012
8388
WX142
NOMESCO Finland
Sub-tenon anesthesy
4.1
10.1
27
66
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
4.2
10.1
26
62
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.6
10.0
233
1494
L28
ICPC
Limited function/disability (L)
1.4
10.0
451
3316
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
2.8
10.0
48
172
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
10.0
122
652
WX702
NOMESCO Finland
Supraglottic ventilation device
1.7
9.8
165
973
34301
ICD-8 Finland
Cerebral spastic infantile paralysis, Diplegia spastica
55.2
9.6
11
*
G47.3
ICD-10 Finland
Sleep apnoea
1.3
9.6
629
4911
Q12.0
ICD-10 Finland
Congenital cataract
15.1
9.5
15
10
S01EX03, ,
ATC
3.0
9.5
41
139
XKC03
NOMESCO Finland
Water cystometry
2.2
9.5
73
329
3431A
ICD-9 Finland
Infantile cerebral palsy, Hemiplegic
100.3
9.4
10
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.1
9.4
85
408
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
3.6
9.4
30
84
N06AX16
ATC
venlafaxine; oral
1.4
9.4
432
3188
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
9.4
230
1495
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
9.3
395
2871
Z2445
NOMESCO Finland
Psychologist
1.9
9.2
118
642
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
3.7
9.1
28
76
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.6
9.1
201
1274
T82
ICPC
Obesity
1.8
9.0
134
762
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
15.6
9.0
14
9
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
9.0
793
6453
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
9.0
258
1736
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.6
9.0
219
1421
SPAT1240
SPAT
Therapeutic discussion
1.5
8.9
315
2212
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
8.9
215
1392
G04BD08
ATC
solifenacin; oral
1.8
8.9
140
811
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
6.8
8.8
21
31
XA800
NOMESCO Finland
Neuropsychological investigation
1.8
8.8
123
688
N06AB04
ATC
citalopram; systemic
1.3
8.7
564
4392
H53.9
ICD-10 Finland
Visual disturbance, unspecified
1.9
8.7
106
567
SPAT1301
SPAT
No procedures
1.3
8.6
787
6429
F01
ICPC
Eye pain
2.0
8.5
93
480
R06.0
ICD-10 Finland
Dyspnoea
1.3
8.5
698
5624
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.6
8.4
221
1459
ZXY60
NOMESCO Finland
2-person team, nurses
3.9
8.4
24
62
A10BA02
ATC
metformin; oral
1.3
8.4
668
5356
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
8.3
8
*
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
8.3
8
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.1
8.3
72
341
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
2.3
8.3
61
270
H05.2
ICD-10 Finland
Exophthalmic conditions
10.8
8.3
15
14
S01CA03
ATC
hydrocortisone and antiinfectives; ophthalmic
3.1
8.3
34
112
WX725
NOMESCO Finland
Noninvasive ventilation
1.7
8.2
150
906
37404
ICD-8 Finland
Cataract, Secundaria
33.4
8.1
10
*
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
11.7
8.1
14
12
N05AF05
ATC
zuclopenthixol; systemic
3.2
8.1
30
93
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
8.0
656
5280
H13
ICPC
Plugged feeling ear
1.4
7.9
464
3555
N03AX18
ATC
lacosamide; systemic
3.4
7.9
27
79
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.7
7.9
127
740
L17
ICPC
Foot/toe symptom/complaint
1.3
7.9
843
7012
CD2S4
NOMESCO Finland
Photography of eye
3.9
7.9
22
56
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.7
7.8
153
941
G04BD12
ATC
mirabegron; oral
1.5
7.8
262
1821
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.4
7.8
50
208
A06AD11
ATC
lactulose; oral
1.4
7.8
313
2251
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.8
319
2303
-1, ,
NOMESCO Finland
1.3
7.8
975
8264
N03AX16
ATC
[U] pregabalin
1.3
7.8
590
4697
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
7.8
551
4345
R51.80
ICD-10 Finland
Headache
1.3
7.7
469
3614
H50.39
ICD-10 Finland
Intermittent heterotropia
45.1
7.7
9
*
A02BC03
ATC
lansoprazole; oral
1.3
7.7
711
5809
H53.4
ICD-10 Finland
Visual field defects
2.4
7.7
49
204
N05AD01
ATC
haloperidol; systemic
2.1
7.6
73
360
A28
ICPC
Limited function/disability NOS
1.4
7.6
368
2736
G81.1
ICD-10 Finland
Spastic hemiplegia
18.4
7.6
11
6
H26.2
ICD-10 Finland
Complicated cataract
2.8
7.6
36
129
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
25.1
7.6
10
*
P99
ICPC
Psychological disorders other
1.9
7.6
98
536
E66.8
ICD-10 Finland
Other obesity
1.6
7.5
170
1084
S01ED51
ATC
timolol, combinations; ophthalmic
1.6
7.5
154
959
M41.9
ICD-10 Finland
Scoliosis, unspecified
2.6
7.4
40
153
R03AC02
ATC
salbutamol; inhalant
1.2
7.4
1646
14804
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
7.3
250
1744
H50.5
ICD-10 Finland
Heterophoria
+∞
7.3
7
*
N06AX21
ATC
duloxetine; oral
1.4
7.3
338
2495
N05AB03
ATC
perphenazine; systemic, rectal
1.8
7.3
95
521
XKD00
NOMESCO Finland
Uroflowmetry
1.4
7.3
273
1941
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.5
7.3
24
69
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.1
7.2
64
306
R42
ICD-10 Finland
Dizziness and giddiness
1.3
7.2
568
4538
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
7.2
530
4196
N05AA01
ATC
chlorpromazine; systemic, rectal
2.7
7.2
38
144
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.3
7.2
54
242
P72
ICPC
Schizophrenia
2.1
7.2
62
294
SPAT1216
SPAT
Assessment of functional ability
1.4
7.2
329
2424
D12
ICPC
Constipation
1.9
7.2
90
488
3430A
ICD-9 Finland
Infantile cerebral palsy, Diplegic
30.1
7.1
9
*
Z02.7
ICD-10 Finland
Issue of medical certificate
1.5
7.1
198
1324
188
Kela drug reimbursment
Psychosis requiring demanding treatment
2.7
7.1
36
134
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.0
787
6573
H03AA01
ATC
levothyroxine sodium; systemic
1.3
7.0
617
5005
IGY02, ,
SPAT
2.2
7.0
54
245
SPAT1139
SPAT
Nutrition survey
1.9
7.0
78
407
N88
ICPC
Epilepsy
3.4
7.0
24
71
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
3.3
7.0
25
76
M54.4
ICD-10 Finland
Lumbago with sciatica
1.3
6.9
515
4083
G91.1
ICD-10 Finland
Obstructive hydrocephalus
5.8
6.9
18
31
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.7
6.9
125
755
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
13.8
6.9
11
8
S01EC01
ATC
acetazolamide; systemic
2.3
6.8
48
209
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.2
6.8
53
241
ICB03, ,
SPAT
3.8
6.8
20
53
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.2
6.8
52
235
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
9.3
6.8
13
14
H50.59
ICD-10 Finland
Heterophor UNS
40.1
6.8
8
*
XCW11
NOMESCO Finland
Assessment of strabismus
40.1
6.8
8
*
F82
ICD-10 Finland
Specific developmental disorder of motor function
5.6
6.7
18
32
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
6.7
2217
20652
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
6.7
360
2721
R02
ICPC
Shortness of breath/dyspnoea
1.4
6.7
329
2453
H52.5
ICD-10 Finland
Disorders of accommodation
22.6
6.7
9
*
37520
ICD-8 Finland
Glaucoma, Secondary
22.6
6.7
9
*
T90
ICPC
Diabetes non-insulin dependent
1.3
6.7
549
4412
S01EE01
ATC
latanoprost; ophthalmic
1.7
6.6
120
725
H40.0
ICD-10 Finland
Glaucoma suspect
1.5
6.6
179
1192
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
3.6
6.6
21
59
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
3.6
6.6
21
59
R5140
NOMESCO Finland
Monitoring the use of the aid
1.4
6.6
270
1951
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.9
6.6
80
430
P29
ICPC
Psychological sympt/compl other
1.5
6.6
233
1640
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
3.3
6.5
24
74
CE2W4
NOMESCO Finland
Eye movement mapping
8.7
6.5
13
15
H57.1
ICD-10 Finland
Ocular pain
1.7
6.5
114
682
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
10.0
6.5
12
12
S18
ICPC
Laceration/cut
1.2
6.5
1254
11076
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.3
6.5
375
2867
N06AX26
ATC
vortioxetine; oral
1.5
6.5
224
1568
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.0
6.5
63
313
WX402
NOMESCO Finland
General anaesthesia
1.3
6.5
625
5122
R4110
NOMESCO Finland
Physiotherapy
1.3
6.5
716
5965
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
1.9
6.4
82
447
S06.0
ICD-10 Finland
Concussion
1.4
6.4
282
2062
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
70.0
6.4
7
*
H50
ICD-10 Finland
Other strabismus
70.0
6.4
7
*
EBA00
NOMESCO Finland
Extraction of tooth
1.2
6.4
1030
8936
WX720
NOMESCO Finland
Own respiration
1.6
6.4
125
772
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
6.4
921
7900
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
1.8
6.3
98
567
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
6.3
571
4643
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
3.5
6.3
21
61
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.3
1817
16656
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
6.3
6
*
3782A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS CONVERGENS INTERMITTENS]
+∞
6.3
6
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.3
6.2
368
2822
3768
FHL
Eye examination under general anesthesia
26.7
6.2
8
*
34408
ICD-8 Finland
Other cerebral paralysis, Alia definita
26.7
6.2
8
*
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
26.7
6.2
8
*
ZXE00
NOMESCO Finland
One hour or less
1.2
6.2
1047
9116
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
6.2
601
4930
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.0
6.1
65
334
N02BE01
ATC
paracetamol; systemic, rectal
1.3
6.1
2723
26021
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.2
6.1
716
6002
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.3
6.1
472
3762
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.5
6.0
195
1349
R35
ICD-10 Finland
Polyuria
1.6
6.0
145
942

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
107
429
2.54
17.65
5.8
6.0
384.88
366.30
umol/l
0.54
97
384
872
6755
1.40
14.85
4.7
3.7
1.02
1.47
kg/l
0.80
610
4471
432
2936
1.54
14.51
10.3
8.6
7.41
7.42
ph
0.81
258
1590
429
2916
1.54
14.39
9.5
8.5
1.46
0.87
mmol/l
2.42
339
2388
1011
8083
1.36
14.02
3.8
4.0
7.39
7.40
ph
0.61
725
5777
369
2452
1.57
13.67
10.5
9.3
121.83
122.47
g/l
0.23
359
2399
424
2934
1.51
13.03
10.0
8.5
5.20
5.10
kpa
1.21
403
2824
424
2935
1.51
13.01
10.0
8.5
12.43
12.79
kpa
0.66
403
2823
866
6850
1.36
12.61
4.0
3.6
0.00
0.22
—
5
60
994
8033
1.34
12.55
3.4
2.9
—
—
—
0
0
381
2615
1.52
12.14
9.9
9.0
95.54
95.88
%
0.47
369
2526
1744
15309
1.30
11.83
4.3
3.7
8.03
5.98
estimate
0.14
312
3181
1565
13558
1.29
11.68
7.7
7.1
1.21
1.21
mmol/l
1.06
1376
11856
1726
15147
1.29
11.65
4.2
3.7
0.00
0.00
estimate
0.80
314
3120
1409
12068
1.29
11.38
7.5
6.6
1.21
1.21
mmol/l
0.96
1325
11257
1747
15396
1.29
11.23
4.3
3.7
0.11
0.11
estimate
0.01
306
3000
239
1514
1.62
10.80
10.0
6.8
24.64
24.44
mmol/l
0.31
228
1446
1211
10257
1.29
10.38
3.7
3.3
32.36
33.63
u/l
0.24
1151
9740
1002
8284
1.30
10.34
2.3
2.2
204.34
209.72
u/l
0.05
943
7898
1423
12311
1.27
10.25
3.8
3.3
6.23
6.21
ph
0.38
805
7137
460
3418
1.40
9.59
2.0
1.7
—
—
—
0
0
2329
21524
1.28
9.16
7.7
8.1
79.61
77.94
u/l
1.02
2243
20541
1814
16285
1.25
9.10
5.9
5.1
6.71
6.58
mmol/l
1.61
1728
15366
1044
8817
1.27
8.81
7.6
6.4
—
—
—
0
0
2604
24459
1.31
8.77
20.7
17.7
13.57
13.49
%
2.45
2579
24147
860
7109
1.28
8.59
4.5
4.3
—
—
—
0
0
223
1471
1.55
8.52
12.1
11.3
15.93
16.17
%
0.54
213
1418
1393
12213
1.24
8.37
4.8
5.1
35.98
36.26
g/l
0.99
1321
11531
1324
11657
1.23
7.34
4.2
3.5
1.97
0.03
estimate
0.49
254
2592
240
1671
1.47
7.12
11.7
11.1
0.68
0.63
%
1.42
240
1658
126
756
1.69
7.11
7.0
5.9
1.39
1.29
mmol/l
0.49
111
653
2950
28394
1.37
7.07
19.2
16.2
139.70
139.68
mmol/l
0.13
2905
27871
1621
14637
1.21
6.79
5.9
6.6
11.25
11.34
umol/l
0.09
1552
14005
1148
10021
1.22
6.77
3.6
3.4
55.34
60.52
ng/l
0.10
696
6206
113
677
1.69
6.45
6.3
4.1
3.88
3.87
mmol/l
0.13
113
670
2951
28475
1.35
6.35
19.2
16.3
3.95
3.95
mmol/l
0.02
2900
27892
2436
22965
1.23
6.34
5.1
4.5
14.68
14.60
pmol/l
0.90
2298
21484
1337
11913
1.21
6.26
2.1
2.0
97.48
97.35
pmol/l
0.03
707
6408
382
2950
1.33
6.17
2.1
2.2
374.19
376.59
nmol/l
0.09
363
2741
241
1729
1.42
6.13
11.7
10.7
1.52
1.33
%
1.15
241
1716
725
6081
1.25
6.13
2.7
2.6
5.80
6.30
e6/l
0.45
668
5504
152
994
1.55
6.11
7.8
5.2
0.89
0.89
%
0.01
143
933
868
7436
1.23
6.01
1.7
1.7
19.74
20.34
nmol/l
0.64
767
6429
1028
8969
1.21
5.91
2.8
2.7
54.46
67.87
u/l
0.87
954
8388
162
1087
1.52
5.81
7.5
4.9
1.67
1.61
%
0.36
153
1023
2268
21300
1.21
5.78
4.8
4.3
11.26
10.88
mm/h
0.68
2160
20171
86
498
1.75
5.59
8.9
7.2
11.47
11.34
mmol/l
0.11
78
445
86
499
1.74
5.55
8.9
7.2
104.33
105.48
mmol/l
1.03
78
446
2611
24901
1.23
5.54
23.2
18.0
332.30
332.65
g/l
1.11
2597
24780
1320
11843
1.19
5.52
12.3
12.8
1.20
1.20
inr
0.04
1109
9826
273
2039
1.37
5.50
2.3
2.3
7.58
7.42
ug/l
0.03
234
1835
1654
15139
1.19
5.48
7.4
6.7
0.04
0.04
e9/l
0.23
1442
13142
617
5145
1.25
5.44
3.9
3.6
314.74
482.24
ng/l
0.83
452
3600
233
3132
0.72
5.29
5.2
4.5
31.43
31.89
%
0.27
170
2195
235
1725
1.39
5.27
12.0
10.9
93.40
94.18
%
0.99
235
1717
1649
15124
1.18
5.24
7.3
6.7
0.58
0.57
e9/l
1.30
1440
13134
110
694
1.61
5.20
1.7
1.6
10.78
38.14
e6/l
1.33
85
510
1685
15488
1.18
5.20
7.4
6.7
2.00
1.96
e9/l
0.19
1506
13796
23
80
2.89
5.19
2.8
2.1
18.40
16.02
umol/l
0.39
23
80
976
8586
1.19
4.97
3.0
2.8
0.00
0.03
0.80
11
150
2071
19407
1.18
4.94
4.8
4.4
—
2.87
—
0
29
2933
28426
1.29
4.92
16.6
14.5
22.72
22.44
mg/l
0.17
2445
23212
1694
15619
1.17
4.92
8.2
6.9
0.19
0.19
e9/l
0.73
1512
13800
110
705
1.58
4.89
1.7
1.6
1843.94
1189.98
e6/l
0.30
90
550
449
3655
1.26
4.86
5.6
6.2
1.07
1.05
mmol/l
0.40
422
3413
1056
9384
1.18
4.76
3.6
3.5
7.56
7.79
mmol/l
0.93
917
8113
1961
18324
1.17
4.74
5.3
4.3
1673.37
1718.61
e6/l
0.01
38
222
493
4069
1.25
4.74
1.7
1.7
1178.46
1162.34
nmol/l
0.15
405
3157
309
2416
1.31
4.60
9.0
8.7
1.27
1.33
mmol/l
0.51
297
2369
1004
8919
1.18
4.49
3.4
3.3
42.06
78.84
e6/l
1.82
796
6711
1462
13386
1.17
4.48
2.6
2.5
75.38
75.99
nmol/l
0.39
1376
12396
34
156
2.19
4.39
1.1
1.1
—
7.11
nmol/l
—
0
28
1069
9578
1.17
4.26
3.1
3.5
2.35
2.35
mmol/l
0.25
977
8823
541
4571
1.22
4.16
3.5
3.8
0.82
0.82
mmol/l
0.35
515
4353
30
134
2.25
4.15
3.7
2.4
146.24
154.79
nmol/l
0.25
25
120
535
4519
1.22
4.12
1.4
1.4
486.02
521.48
titre
0.17
113
948
1799
16797
1.16
4.10
11.7
9.9
4.14
4.04
e9/l
1.05
1575
14667
284
2231
1.30
4.10
1.3
1.3
102.96
233.93
u/ml
2.73
266
2084
955
8512
1.17
4.02
4.1
4.1
11.50
8.46
mg/mmol
0.61
616
5341
206
1554
1.35
3.96
11.4
11.0
24.47
24.23
mmol/l
0.52
198
1525
2756
26651
1.21
3.91
6.1
5.4
1.82
1.84
mu/l
0.33
2623
25100
1153
10458
1.16
3.83
4.0
3.8
73.99
91.07
e6/l
0.54
824
7195
99
659
1.52
3.80
1.7
1.6
—
—
—
0
0
91
595
1.54
3.79
2.6
3.1
31.17
35.68
umol/l
1.03
83
547
935
8360
1.17
3.74
3.5
3.5
47.43
47.81
mg/l
0.02
610
5330
236
1833
1.31
3.72
2.9
3.0
114.69
179.21
ng/l
3.74
212
1654
1496
13853
1.15
3.67
7.5
6.8
2.84
2.83
%
0.09
1416
13064
866
7711
1.17
3.65
3.2
3.2
0.42
0.38
e6/l
0.17
657
5570
1499
13888
1.15
3.64
7.7
6.9
8.62
8.65
%
0.13
1420
13107
1540
14308
1.14
3.56
7.5
6.8
28.50
28.70
%
0.29
1466
13646
296
2382
1.27
3.56
2.7
2.9
10.63
10.58
g/l
0.06
277
2211
1494
13859
1.14
3.52
7.6
6.9
0.70
0.69
%
0.27
1413
13049
64
394
1.64
3.46
1.4
1.5
—
—
—
0
0
64
394
1.64
3.46
1.4
1.5
—
—
—
0
0
64
394
1.64
3.46
1.4
1.5
—
—
—
0
0
64
394
1.64
3.46
1.4
1.5
—
—
—
0
0
31
152
2.05
3.45
4.9
2.9
142.11
157.12
umol/l
0.11
18
82
102
699
1.47
3.44
1.7
1.5
3.72
3.68
mmol/l
0.16
97
663
44
244
1.81
3.44
1.1
1.1
224.23
264.69
mg/l
0.66
39
211
45
252
1.80
3.41
1.2
1.2
36.49
39.72
mg/l
0.26
37
210
108
752
1.45
3.36
1.4
1.3
—
—
—
0
0
800
7123
1.16
3.34
3.4
3.2
961.71
1119.91
ng/l
0.84
678
6016
599
5214
1.18
3.31
2.7
2.9
528.87
528.53
mosm/kgh2o
0.01
521
4559
908
8167
1.15
3.30
4.7
3.8
0.00
0.00
estimate
1.94
293
2944
409
3445
1.21
3.24
2.5
2.9
8.64
7.29
umol/l
0.39
346
3025
36
192
1.88
3.19
1.3
1.2
0.71
0.58
ratio
1.11
20
117
680
5998
1.17
3.19
1.4
1.3
34.63
26.83
iu/ml
0.45
213
1815
421
3565
1.21
3.16
1.6
1.5
—
—
—
0
0
555
4821
1.18
3.14
3.0
2.8
0.96
1.24
e6/l
0.86
300
2494
469
4024
1.19
3.06
2.2
2.0
—
—
—
0
0
293
2402
1.24
3.03
10.5
9.8
—
—
—
0
0
123
897
1.39
3.00
1.2
1.3
94.12
119.88
titre
0.32
17
84
330
2743
1.23
3.00
4.4
4.3
7.38
7.38
ph
0.05
209
1566
265
2153
1.25
2.97
2.6
2.4
0.34
0.45
e6/l
0.64
256
2051
3071
30163
1.27
2.97
20.4
17.9
73.82
73.94
umol/l
0.07
3040
29858
125
916
1.38
2.96
2.1
2.1
3.17
9.43
iu/l
0.54
59
396
255
2065
1.25
2.94
3.7
3.5
4.44
4.54
pmol/l
1.01
237
1857
31
163
1.91
2.89
2.3
2.0
—
—
—
0
0
1504
14076
1.13
2.89
7.4
6.7
56.75
56.63
%
0.15
1451
13512
207
1639
1.28
2.88
1.2
1.1
1.28
0.89
u/ml
—
6
16
319
2654
1.22
2.88
4.1
4.3
1.91
1.74
mmol/l
0.33
275
2294
1312
12187
1.13
2.84
2.0
1.9
1.41
1.39
mmol/l
0.55
1143
10550
1162
12543
0.89
2.78
3.1
2.9
—
—
—
0
0
12
40
3.01
2.69
1.6
1.6
—
—
—
0
0
149
1145
1.32
2.62
3.9
3.1
—
—
—
0
0
13
49
2.66
2.62
1.0
1.2
—
—
—
0
0
13
49
2.66
2.62
1.0
1.2
—
—
—
0
0
13
49
2.66
2.62
1.0
1.2
—
—
—
0
0
533
4687
1.16
2.59
2.6
2.5
12.99
13.77
umol/l
1.97
501
4396
622
5534
1.15
2.58
1.8
1.7
69597526.21
29615977.57
pmol/l
0.55
546
4734
52
330
1.58
2.57
2.2
2.1
—
—
—
0
0
51
323
1.59
2.54
1.5
1.5
282.92
280.52
mosm/kgh2o
0.25
36
245
10
31
3.23
2.51
1.6
1.3
—
—
—
0
0
195
2415
0.80
2.50
3.7
4.0
7.36
7.35
ph
0.14
141
1778
322
2726
1.20
2.46
4.4
4.2
5.86
5.82
kpa
0.32
315
2656
615
5511
1.14
2.30
1.4
1.3
6.68
9.84
u/ml
0.89
249
2251
350
4049
0.85
2.24
1.9
1.9
3.52
3.53
ratio
0.06
259
3049
220
1812
1.23
2.24
4.2
4.1
5.15
5.14
kpa
0.04
214
1749
810
7413
1.12
2.16
2.4
2.6
333.80
331.16
umol/l
0.30
719
6672
802
7338
1.12
2.15
2.5
2.3
2.65
2.71
mg/l
0.26
719
6380
260
3072
0.83
2.14
1.6
1.7
3.56
3.52
mmol/l
0.22
170
2077
271
2295
1.20
2.10
4.2
3.8
4.92
4.67
kpa
0.94
264
2229
226
1882
1.22
2.09
1.7
1.9
1.24
1.35
g/l
0.76
212
1755
280
2391
1.19
1.99
7.1
8.3
8.91
8.92
mmol/l
0.01
265
2311
34
209
1.63
1.97
1.2
1.2
—
—
—
0
0
309
2663
1.18
1.97
1.2
1.2
—
—
—
0
0
486
4336
1.14
1.95
2.7
2.5
2.43
2.37
g/l
1.29
450
4044
5
11
4.55
1.94
4.0
4.4
—
—
—
0
0
91
685
1.34
1.93
4.3
3.0
—
—
—
0
0
244
2065
1.20
1.92
1.2
1.3
—
—
—
0
0
77
565
1.37
1.92
4.6
3.8
—
—
—
0
0
476
4246
1.14
1.92
2.2
2.6
112.95
117.68
ug/g
0.12
375
3456
787
7239
1.11
1.91
4.2
4.2
90.88
92.19
%
0.81
764
7089
1386
13118
1.10
1.90
11.8
11.1
0.00
0.00
e9/l
0.00
1121
10694
725
6641
1.12
1.90
1.5
1.5
2.44
2.30
g/l
1.09
456
4253
168
1372
1.24
1.90
1.5
1.7
346.92
285.17
mu/l
1.31
155
1244
107
829
1.30
1.86
1.1
1.2
—
—
—
0
0
20
107
1.87
1.86
1.2
1.1
0.15
1.90
u/ml
1.42
14
60
115
1456
0.78
1.85
1.2
1.1
1.53
1.54
g/l
0.15
115
1456
825
7625
1.11
1.83
1.4
1.4
1.67
1.67
u/ml
0.00
238
2130
126
1002
1.27
1.80
1.5
1.8
1.27
1.19
g/l
1.99
116
951
445
3972
1.14
1.78
2.6
2.6
21.97
23.40
%
1.63
422
3725
210
1767
1.20
1.78
4.3
4.1
7.41
7.42
ph
0.06
175
1463
122
970
1.27
1.76
1.5
1.9
0.25
0.23
g/l
0.79
112
920
730
6719
1.11
1.75
1.9
1.9
1.18
1.10
mg/l
0.27
560
5100
2745
26898
1.12
1.73
5.2
4.6
5.91
5.83
mmol/l
2.15
2595
25135
13
61
2.14
1.71
1.0
1.0
—
—
—
0
0
65
475
1.38
1.70
1.5
1.4
59.59
62.12
mmol/l
0.18
49
388
76
1003
0.75
1.69
1.5
1.5
60.82
61.26
ug/l
0.03
57
830
151
1241
1.23
1.64
1.4
1.3
0.25
0.93
u/ml
1.55
11
92
762
7062
1.10
1.59
4.7
4.7
—
—
—
0
0
94
734
1.29
1.59
3.3
3.1
1.77
1.93
index
0.06
56
398
10
43
2.33
1.58
1.7
2.2
6.18
7.58
mmol/l
—
5
23
123
994
1.25
1.57
2.7
1.9
1.51
1.95
ug/l
0.37
113
896
109
869
1.26
1.57
1.1
1.1
1.06
5.40
eliau/ml
2.90
18
126
254
2201
1.17
1.56
1.4
1.4
31.07
27.62
iu/l
0.88
205
1876
152
1258
1.22
1.56
1.4
1.3
200.05
227.15
miu/ml
0.38
59
622
145
1750
0.82
1.55
1.5
1.6
988.01
1020.39
mu/l
0.17
122
1455
251
2176
1.17
1.54
2.7
2.9
70.21
70.84
e9/l
0.10
184
1566
190
1613
1.19
1.50
1.9
2.5
—
—
—
0
0
38
547
0.69
1.48
1.0
1.1
0.01
0.23
u/ml
3.18
15
178
2688
26364
1.11
1.48
6.5
5.7
39.16
38.53
mmol/mol
3.03
2570
25043
1553
14887
1.08
1.48
3.5
3.2
100.66
106.44
ug/l
0.48
1489
14115
141
1166
1.22
1.47
2.2
2.5
20.80
20.80
s
0.00
122
1023
112
1379
0.81
1.47
1.2
1.1
0.59
0.65
ratio
—
10
164
96
761
1.27
1.46
1.2
1.2
55.84
39.90
u/ml
0.46
16
81
237
2055
1.17
1.46
3.7
3.9
83.86
82.35
ng/l
0.09
212
1811
487
4430
1.12
1.46
3.0
2.9
3.94
2.95
e6/l
0.59
226
2109
449
4066
1.12
1.45
2.1
2.4
29.33
29.52
s
0.34
441
3945
13
66
1.97
1.43
1.2
1.3
60.00
33.48
%
—
6
44
7
151
0.46
1.43
1.0
1.2
—
—
—
0
0
323
2873
1.14
1.40
2.5
2.8
1.73
1.78
%
0.46
292
2583
231
2007
1.16
1.40
1.3
1.3
51.08
51.44
au/ml
0.01
11
129
81
633
1.29
1.39
2.3
2.3
131.69
130.96
g/l
0.10
67
505
159
1339
1.20
1.39
1.6
1.9
5.08
7.01
iu/ml
0.94
42
322
7
29
2.42
1.39
1.1
1.2
1.42
1.83
umol/24h
—
7
29
114
929
1.24
1.39
1.3
1.3
2.48
8.09
u/ml
1.90
17
142
235
2046
1.16
1.39
2.2
2.8
66.55
66.72
g/l
0.12
221
1900
437
3965
1.12
1.37
1.7
1.6
—
—
—
0
0
121
995
1.22
1.36
1.3
1.2
20.54
37.55
u/ml
—
5
54
113
924
1.23
1.34
1.4
1.3
4.74
6.53
u/ml
0.19
16
86
3151
31242
1.20
1.33
26.1
22.0
6.80
6.68
e9/l
1.29
3085
30637
151
1274
1.19
1.31
3.1
2.2
—
—
—
0
0
3149
31224
1.19
1.31
26.1
21.9
258.37
257.31
e9/l
0.41
3088
30697
3150
31235
1.20
1.31
26.6
22.4
40.59
40.82
%
0.61
3124
30967
3150
31235
1.20
1.31
26.0
21.9
4.53
4.52
e12/l
0.62
3082
30642
247
2174
1.15
1.27
2.4
2.4
21.14
19.53
au/ml
0.11
31
274
570
5270
1.10
1.26
2.7
2.9
2.43
2.44
mmol/l
0.77
505
4744
3149
31231
1.19
1.26
25.9
21.8
30.14
30.23
pg
2.24
3123
30977
3149
31231
1.19
1.26
26.0
21.8
90.49
90.67
fl
1.64
3123
30977
104
850
1.23
1.26
1.9
2.3
10.87
10.32
g/l
0.60
95
771
3150
31244
1.19
1.24
26.2
22.1
135.76
135.89
g/l
0.20
3123
30990
3036
30038
1.14
1.21
12.5
11.5
27.39
26.56
u/l
1.44
2979
29378
20
124
1.62
1.20
1.3
1.8
—
—
—
0
0
19
117
1.63
1.18
1.2
1.0
—
—
—
0
0
906
8570
1.08
1.17
3.5
3.1
0.01
0.05
estimate
0.80
255
2505
20
125
1.60
1.17
3.5
2.5
—
—
—
0
0
23
149
1.55
1.17
1.8
2.2
6.88
8.27
mmol/l
1.45
23
149
0
34
0.00
1.16
0.0
1.0
—
87.53
—
0
34
47
621
0.75
1.14
1.1
1.1
3.47
4.67
u/ml
0.40
26
304
150
1285
1.18
1.13
3.4
3.2
1.02
1.02
ratio
0.78
131
1163
35
250
1.40
1.12
1.5
1.5
3266.50
108531.24
e6/l
1.76
24
164
152
1305
1.17
1.12
1.1
1.1
—
—
—
0
0
97
1171
0.82
1.11
1.5
1.5
—
—
—
0
0
110
919
1.20
1.10
1.9
2.4
2295.51
365.48
ug/l
0.52
99
867
196
1719
1.15
1.09
1.2
1.2
—
—
—
0
0
7
139
0.50
1.09
2.6
2.7
2135.71
2013.51
ml
—
7
127
146
1255
1.17
1.07
2.0
1.9
—
—
—
0
0
44
579
0.76
1.06
1.0
1.1
3.11
4.51
u/ml
0.33
23
257
112
942
1.20
1.05
5.5
5.4
1.41
1.40
mg/l
0.04
104
883
10
178
0.56
1.03
1.1
1.4
136.60
131.84
nmol/l
—
10
178
7
34
2.06
1.03
5.0
2.8
—
—
—
0
0
18
114
1.58
1.02
4.7
2.6
0.11
0.24
e9/l
2.26
13
59
11
189
0.58
1.00
1.0
1.2
9.73
8.58
mm/h
0.24
11
189
1377
13278
1.06
1.00
2.7
2.7
—
—
estimate
—
0
0
7
133
0.53
0.98
1.1
1.1
—
—
—
0
0
40
301
1.33
0.97
1.1
1.1
—
—
—
0
0
326
3565
0.91
0.97
1.3
1.3
—
—
—
0
0
81
668
1.22
0.95
1.6
1.5
—
—
—
0
0
65
802
0.81
0.95
1.5
1.5
—
—
—
0
0
193
1711
1.14
0.95
4.1
4.6
24.41
24.14
mmol/l
0.57
188
1694
32
233
1.38
0.95
1.1
1.0
—
—
—
0
0
183
1617
1.14
0.95
3.0
2.2
—
—
—
0
0
62
768
0.80
0.94
1.4
1.4
1.29
1.25
mm
0.28
41
545
30
217
1.39
0.93
1.1
1.4
—
—
—
0
0
12
70
1.72
0.92
1.6
1.4
36.92
49.81
%
0.53
12
60
24
167
1.44
0.92
1.5
1.4
1.33
1.27
nmol/l
0.13
17
123
23
159
1.45
0.91
1.7
2.1
70.74
103.55
ng/l
2.61
23
159
14
219
0.64
0.90
1.0
1.1
0.08
2.00
u/ml
—
6
49
30
219
1.37
0.89
1.1
1.4
82803.68
76900.62
e6/l
0.04
19
122
45
350
1.29
0.88
1.5
2.5
—
—
—
0
0
66
538
1.23
0.88
4.1
4.2
—
—
—
0
0
2131
20871
1.06
0.87
3.7
3.3
45.85
43.91
u/l
0.30
2040
19932
97
823
1.18
0.87
2.5
2.2
10.70
11.38
mg/l
0.37
92
772
152
1336
1.14
0.87
2.3
2.3
—
—
—
0
0
64
780
0.82
0.86
1.4
1.5
—
—
—
0
0
658
6947
0.93
0.85
2.3
2.3
—
—
—
0
0
186
1660
1.13
0.85
1.1
1.1
291.25
88.35
titre
—
8
51
17
112
1.52
0.84
3.6
2.7
—
—
—
0
0
34
256
1.33
0.84
1.1
1.4
2642.48
2527.92
e6/l
0.05
25
174
309
2837
1.10
0.84
2.4
2.5
35.44
56.89
u/l
0.66
255
2408
182
1625
1.13
0.83
3.0
2.1
—
—
—
0
0
169
1504
1.13
0.82
3.1
2.2
—
—
—
0
0
12
73
1.65
0.81
1.3
1.2
—
—
—
0
0
71
590
1.21
0.81
1.5
1.4
19.91
27.01
u/l
1.31
59
482
25
340
0.73
0.80
1.2
1.3
—
—
nmol/l
—
0
0
0
25
0.00
0.79
0.0
1.6
—
341.48
—
0
25
1128
11686
0.95
0.79
2.0
2.1
—
—
—
0
0
54
438
1.24
0.78
2.6
1.6
451.36
337.20
mu/l
0.73
45
349
113
982
1.16
0.78
2.0
2.3
3.65
3.72
g/l
0.26
106
909
5
96
0.52
0.78
2.4
2.8
—
—
—
0
0
30
225
1.34
0.78
3.6
2.8
507.44
579.69
e6/l
0.44
25
176
0
27
0.00
0.77
0.0
1.5
—
—
—
0
0
182
1634
1.12
0.77
3.0
2.2
—
—
—
0
0
113
983
1.15
0.77
2.0
2.3
4.30
4.25
g/l
0.28
106
909
410
3834
1.08
0.75
3.4
3.2
4.11
4.59
e9/l
1.52
371
3398
216
2373
0.90
0.74
1.3
1.4
—
—
—
0
0
74
624
1.19
0.74
1.6
1.5
158.74
146.69
au/ml
0.29
19
186
287
2646
1.09
0.74
2.4
2.1
0.03
0.01
estimate
0.25
59
595
81
689
1.18
0.74
1.7
1.7
18201.81
11967.63
e6/l
0.43
58
472
67
561
1.20
0.73
1.1
1.1
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
18
125
1.44
0.72
2.0
2.2
2.29
2.69
ug/l
0.12
12
107
32
246
1.30
0.72
1.8
2.5
33.12
27.49
mg/l
0.27
26
166
103
1178
0.87
0.70
1.7
1.7
—
—
—
0
0
11
69
1.60
0.68
1.7
2.7
2.15
2.84
mmol/l
0.88
11
63
99
863
1.15
0.68
1.2
1.2
—
—
—
0
0
52
628
0.83
0.68
2.3
2.3
0.93
0.88
nmol/l
0.19
45
540
19
261
0.73
0.67
3.5
2.8
—
—
—
0
0
177
1603
1.11
0.67
3.0
2.1
—
—
—
0
0
14
94
1.49
0.66
1.9
1.4
8.51
8.99
mmol/l
0.11
14
94
66
558
1.19
0.66
1.1
1.1
—
—
—
0
0
20
271
0.74
0.65
3.0
4.1
—
—
—
0
0
287
2664
1.08
0.65
1.5
1.5
—
—
—
0
0
81
699
1.16
0.64
1.3
1.3
240.26
259.20
u/ml
0.30
50
417
63
533
1.19
0.63
3.4
3.4
25.57
24.54
mg/l
0.07
44
368
22
292
0.75
0.63
1.0
1.1
26.65
17.00
u/ml
—
10
123
17
234
0.73
0.62
1.0
2.1
—
—
—
0
0
27
208
1.30
0.62
1.0
1.1
361.25
396.26
nmol/l
0.36
20
192
839
8703
0.95
0.61
1.5
1.5
—
—
—
0
0
578
5515
1.06
0.60
1.7
1.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
158
1433
1.11
0.60
1.6
1.8
0.28
0.32
mg/l
0.44
73
701
0
22
0.00
0.59
0.0
3.3
—
0.60
—
0
8
0
22
0.00
0.59
0.0
1.0
—
16.38
—
0
8
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
17
123
1.38
0.57
1.0
1.1
—
—
—
0
0
6
37
1.62
0.55
1.2
1.1
—
—
—
0
0
22
285
0.77
0.55
1.1
1.2
—
—
—
0
0
225
2087
1.08
0.55
2.6
3.7
1.23
1.23
mmol/l
0.32
191
1810
246
2291
1.08
0.54
2.9
2.4
6.04
6.10
ph
0.39
169
1481
20
151
1.33
0.54
1.3
1.4
9.70
13.68
u/l
3.50
20
145
58
497
1.17
0.53
1.1
1.1
1.22
2.85
eliau/ml
2.75
29
242
22
169
1.30
0.53
1.0
1.0
740.57
765.71
ng/l
0.11
14
114
22
169
1.30
0.53
1.0
1.0
291.43
294.99
ng/l
0.02
14
117
140
1275
1.10
0.52
4.8
4.2
—
—
—
0
0
27
336
0.80
0.50
3.8
2.2
0.83
0.88
%
0.15
21
220
122
1105
1.11
0.50
1.6
1.9
1.53
1.52
g/l
0.03
107
975
287
2700
1.07
0.49
2.3
2.4
0.22
0.22
g/l
0.03
274
2538
14
101
1.39
0.49
1.0
1.1
—
—
—
0
0
14
101
1.39
0.49
1.1
1.3
28.29
28.56
s
0.08
14
101
15
201
0.75
0.49
1.1
1.4
75.20
76.68
umol/l
0.10
15
201
40
335
1.20
0.48
1.0
1.1
—
—
—
0
0
11
76
1.45
0.48
1.0
1.2
—
—
—
0
0
24
190
1.27
0.48
1.0
1.2
—
—
—
0
0
15
200
0.75
0.47
1.9
2.1
0.56
1.54
u/field
—
9
112
133
1215
1.10
0.47
1.2
1.2
—
—
—
0
0
12
85
1.41
0.46
1.4
1.4
—
—
—
0
0
25
310
0.80
0.46
5.0
5.2
104.30
62.93
u/ml
—
9
97
59
675
0.87
0.46
1.1
1.1
—
—
—
0
0
166
1537
1.08
0.45
2.6
2.2
2012.61
5585.79
u/l
2.49
56
603
184
1712
1.08
0.44
1.1
1.1
—
—
—
0
0
114
1038
1.10
0.44
1.5
1.3
—
—
—
0
0
11
152
0.72
0.44
1.5
1.3
—
—
—
0
0
59
672
0.88
0.44
1.1
1.1
—
—
—
0
0
54
470
1.15
0.43
2.3
2.5
4.90
6.45
umol/l
0.93
41
350
63
712
0.88
0.42
1.0
1.1
0.74
1.44
u/ml
0.65
39
361
19
240
0.79
0.42
1.1
1.1
1.17
1.31
u/ml
—
8
64
29
349
0.83
0.42
1.1
1.3
0.17
0.23
nmol/l
0.50
21
274
6
95
0.63
0.42
1.2
1.1
—
—
—
0
0
93
842
1.11
0.41
1.3
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
68.20
—
0
10
360
3769
0.95
0.41
1.3
1.3
—
—
—
0
0
26
315
0.82
0.40
1.1
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.2
6.04
5.81
mmol/l
—
5
34
17
132
1.29
0.40
3.1
2.7
34.54
79.98
ug/l
0.35
17
120
34
287
1.19
0.40
1.4
1.3
1.30
1.44
nmol/l
0.33
28
258
20
159
1.26
0.40
2.4
2.0
1.89
1.87
umol/l
0.02
20
143
115
1056
1.09
0.39
1.5
1.5
13.09
10.24
u/l
0.94
85
844
130
1203
1.08
0.38
2.0
1.6
41.35
13.44
iu/ml
—
6
37
57
505
1.13
0.37
1.3
1.3
3.36
4.61
u/ml
0.54
28
227
35
299
1.17
0.37
1.5
1.6
47.43
59.44
%
0.92
23
184
407
4234
0.96
0.37
1.5
1.5
—
—
—
0
0
26
216
1.21
0.36
1.2
1.5
—
—
—
0
0
248
2353
1.06
0.36
2.5
2.4
12.80
13.13
nmol/l
0.25
229
2151
9
71
1.27
0.36
1.1
1.5
1.97
0.86
u/ml
—
9
71
46
403
1.14
0.36
1.3
1.9
—
1137.78
—
0
18
12
90
1.33
0.35
1.8
1.7
38.89
40.83
g/l
0.97
12
90
5
80
0.62
0.35
1.0
1.0
57.68
34.20
iu/ml
—
5
80
111
1025
1.09
0.35
1.8
1.9
—
—
—
0
0
40
348
1.15
0.34
2.0
2.4
—
—
—
0
0
182
1931
0.94
0.34
1.8
1.7
—
—
—
0
0
273
2604
1.05
0.34
4.7
4.9
1.04
0.89
%
0.45
81
763
12
155
0.77
0.33
1.8
2.5
510.29
498.80
min
—
7
114
6
46
1.30
0.33
1.0
1.5
—
—
—
0
0
26
219
1.19
0.33
2.8
3.2
311.47
43.20
mg/l
0.50
13
162
50
560
0.89
0.32
1.8
1.7
0.81
0.76
g/l
0.06
43
438
260
2483
1.05
0.32
4.2
4.7
0.97
0.66
%
0.73
74
728
54
485
1.12
0.30
1.2
1.2
—
—
—
0
0
7
54
1.30
0.30
1.1
1.4
—
19.14
—
0
7
31
268
1.16
0.30
1.1
1.2
1.44
0.92
u/ml
0.21
18
142
54
486
1.11
0.30
1.3
1.7
—
—
—
0
0
7
56
1.25
0.29
6.1
2.8
5.14
5.16
ug/l
—
7
56
34
297
1.15
0.29
4.1
3.8
7.21
7.17
mmol/l
0.01
24
259
7
57
1.23
0.29
6.7
6.1
5.64
5.40
kpa
—
7
57
88
949
0.93
0.28
2.6
3.8
233.88
1714.15
u/ml
0.80
74
823
11
85
1.30
0.28
1.5
1.8
—
—
—
0
0
8
63
1.27
0.27
1.4
1.1
—
—
—
0
0
69
633
1.09
0.27
1.2
1.1
52.21
16.77
au/ml
—
10
170
9
120
0.75
0.27
3.0
2.1
28.44
29.53
%
—
9
120
11
139
0.79
0.27
1.0
1.4
160.45
169.03
mmol/24h
0.12
11
139
20
236
0.85
0.26
1.6
1.5
—
—
—
0
0
31
272
1.14
0.26
4.0
1.9
34.59
20.40
ug/l
0.50
31
266
17
141
1.21
0.26
1.1
1.1
126.59
188.92
iu/ml
1.15
17
141
37
415
0.89
0.26
1.2
1.3
—
0.36
nmol/l
—
0
27
26
225
1.16
0.26
1.1
1.1
—
—
—
0
0
903
9192
0.98
0.25
2.3
2.4
—
—
—
0
0
2659
26729
0.97
0.24
4.3
4.0
1.31
1.29
mmol/l
1.27
2525
25127
73
787
0.93
0.24
1.1
1.1
—
—
—
0
0
389
4005
0.97
0.24
3.0
3.0
0.84
0.71
ug/l
0.51
243
2351
6
84
0.71
0.24
3.0
3.2
—
—
—
0
0
53
579
0.91
0.24
1.8
1.9
—
—
—
0
0
87
813
1.07
0.23
1.9
2.6
—
—
—
0
0
10
125
0.80
0.23
1.1
1.7
0.57
0.50
e9/l
—
10
125
82
767
1.07
0.22
1.9
3.5
41.98
60.21
mg/l
1.01
67
657
49
535
0.91
0.22
1.3
1.2
—
—
—
0
0
23
200
1.15
0.22
1.4
1.4
33.85
34.63
nmol/l
0.04
18
174
25
219
1.14
0.22
1.8
1.5
37.57
33.88
%
0.18
19
126
672
6590
1.02
0.22
5.0
4.8
2.53
2.25
ug/l
0.32
610
6005
5
41
1.22
0.22
1.0
1.3
—
—
—
0
0
27
305
0.88
0.22
2.3
2.5
1.49
1.53
g/24h
0.02
15
183
111
1050
1.06
0.22
5.4
4.4
24.74
24.77
mmol/l
0.04
105
981
43
391
1.10
0.22
1.3
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.81
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
132.17
—
0
6
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
4.40
—
0
10
248
2566
0.96
0.21
3.1
4.4
7.92
18.18
ug/l
1.46
181
2042
59
546
1.08
0.21
1.2
1.2
—
—
—
0
0
83
779
1.07
0.21
1.7
1.9
197.84
203.60
pmol/l
0.21
77
738
5
43
1.16
0.21
1.4
1.4
—
8.51
—
0
15
0
13
0.00
0.21
0.0
5.2
—
392.62
—
0
13
0
13
0.00
0.21
0.0
1.0
—
0.08
—
0
8
0
14
0.00
0.20
0.0
1.1
—
0.03
—
0
14
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
9
111
0.81
0.20
4.2
4.7
—
—
—
0
0
6
50
1.20
0.19
1.7
1.4
—
—
—
0
0
53
491
1.08
0.19
1.2
1.2
—
—
—
0
0
28
312
0.90
0.19
1.0
1.4
—
—
—
0
0
6
52
1.15
0.19
1.0
1.0
3.47
5.45
u/ml
—
6
52
51
472
1.08
0.19
1.4
1.5
2.54
4.09
ug/l
1.32
40
423
43
395
1.09
0.18
1.7
1.5
33.09
86.66
mu/l
1.26
38
361
35
318
1.10
0.18
1.5
2.6
—
—
—
0
0
23
259
0.89
0.18
2.5
3.4
65.39
55.95
%
1.82
18
232
37
404
0.91
0.18
1.9
3.6
1.20
1.50
%
0.28
32
372
404
3950
1.03
0.18
1.2
1.2
—
—
—
0
0
2800
28097
0.98
0.18
5.0
4.7
1.44
1.47
mmol/l
3.79
2668
26608
28
252
1.11
0.17
1.3
1.2
—
—
—
0
0
122
1167
1.05
0.17
1.3
1.3
—
—
—
0
0
11
91
1.21
0.17
1.5
1.3
—
—
—
0
0
81
767
1.06
0.17
1.9
3.6
42.90
43.10
mg/l
0.01
67
658
19
215
0.88
0.16
1.3
1.7
—
—
—
0
0
251
2441
1.03
0.16
1.2
1.2
123.07
149.75
u/ml
0.57
93
922
49
525
0.93
0.16
1.0
1.1
3.67
17762.55
iu/ml
—
6
132
259
2526
1.03
0.15
5.0
5.2
0.03
0.22
%
0.82
61
612
21
188
1.12
0.14
1.1
1.1
1727.76
1507.36
miu/ml
0.34
21
188
57
537
1.06
0.14
5.2
3.9
2.96
2.47
mmol/l
0.46
41
345
320
3270
0.98
0.14
1.3
1.4
—
—
—
0
0
27
246
1.10
0.14
4.4
3.3
18.43
13.59
index
0.49
14
161
27
247
1.09
0.13
1.3
1.1
—
—
—
0
0
98
941
1.04
0.13
2.8
3.9
319.87
362.87
mg/l
0.20
52
445
141
1365
1.03
0.13
2.4
2.2
0.02
0.01
estimate
0.17
51
460
90
863
1.04
0.13
9.9
8.9
—
—
—
0
0
13
113
1.15
0.13
1.2
1.2
—
0.11
—
0
8
11
127
0.87
0.12
1.2
1.0
—
—
—
0
0
10
85
1.18
0.12
1.8
2.0
—
—
—
0
0
26
239
1.09
0.12
1.3
1.2
106.81
113.77
pmol/l
0.37
26
239
22
240
0.92
0.11
1.1
1.1
—
—
—
0
0
2816
28223
0.98
0.11
5.2
4.8
4.66
4.73
mmol/l
3.45
2689
26853
28
260
1.08
0.10
1.0
1.1
16.31
9.13
iu/ml
—
8
73
68
652
1.04
0.10
1.4
1.4
0.55
0.42
nmol/l
0.25
46
501
19
208
0.91
0.10
1.2
1.4
203.59
211.96
pmol/l
0.06
19
208
81
840
0.96
0.10
1.4
1.4
264.21
296.73
ug/g
0.59
43
470
21
228
0.92
0.10
1.1
1.3
—
—
—
0
0
5
46
1.09
0.09
1.2
1.2
—
—
—
0
0
661
6674
0.99
0.09
2.2
2.0
—
—
—
0
0
10
87
1.15
0.09
1.5
1.5
10.80
12.31
g/l
—
5
66
5
48
1.04
0.09
1.2
1.9
—
—
—
0
0
72
746
0.96
0.09
1.2
1.3
—
—
—
0
0
6
55
1.09
0.08
1.0
1.4
3.03
3.73
mmol/l
—
6
50
5
65
0.77
0.08
1.0
1.3
—
—
—
0
0
6
71
0.84
0.07
1.0
1.1
0.36
5.01
u/ml
—
6
61
38
363
1.05
0.07
2.3
2.3
—
—
—
0
0
8
94
0.85
0.06
2.1
2.9
0.60
0.62
mmol/l
—
8
94
232
2288
1.02
0.06
4.6
3.8
—
—
—
0
0
88
858
1.03
0.06
1.1
1.1
1.29
2.30
u/ml
1.07
53
461
9
105
0.86
0.06
1.0
1.0
—
—
—
0
0
9
105
0.86
0.06
1.1
1.1
—
—
—
0
0
78
760
1.03
0.06
1.1
1.1
2.97
4.98
u/ml
1.02
47
421
12
109
1.10
0.06
2.2
1.5
14.83
15.04
pmol/l
0.07
12
93
117
1192
0.98
0.05
1.7
1.7
7.78
13.49
u/ml
1.76
39
315
28
267
1.05
0.05
1.4
1.1
—
—
—
0
0
10
110
0.91
0.05
1.7
1.9
0.30
0.00
estimate
—
10
110
23
242
0.95
0.05
1.0
1.1
7.54
2.25
u/ml
0.32
12
87
36
373
0.96
0.04
1.1
1.2
—
—
—
0
0
25
239
1.05
0.04
3.3
3.6
15.32
25.99
mu/l
2.38
25
231
17
160
1.06
0.04
2.3
2.0
28.66
29.56
umol/l
0.18
17
149
24
251
0.96
0.04
1.0
1.2
—
—
—
0
0
25
261
0.96
0.04
1.0
1.1
—
—
—
0
0
42
432
0.97
0.03
1.3
1.8
—
—
—
0
0
12
129
0.93
0.03
1.9
1.7
—
—
—
0
0
23
220
1.05
0.03
1.3
1.9
8.26
6.67
mmol/l
0.81
16
155
13
139
0.93
0.03
2.1
2.5
15.62
16.55
%
0.46
13
139
67
682
0.98
0.03
1.9
3.3
1.95
3.51
ratio
0.86
40
378
373
3711
1.01
0.03
2.1
1.8
—
—
—
0
0
40
409
0.98
0.02
3.3
3.1
37.91
73.21
u/ml
0.30
40
402
10
107
0.93
0.02
1.1
1.7
—
—
—
0
0
10
107
0.93
0.02
1.0
1.0
—
—
—
0
0
34
332
1.02
0.01
1.7
1.4
—
—
—
0
0
14
147
0.95
0.01
42.1
42.0
6.95
7.29
ug/l
0.31
14
134
56
552
1.01
0.01
2.3
2.6
77.95
98.88
ug/min
0.27
34
337
65
658
0.99
0.01
3.2
3.1
58.84
58.01
%
0.24
65
658
74
732
1.01
0.01
1.1
1.1
0.29
1.13
u/ml
2.22
34
332
33
337
0.98
0.01
1.8
1.4
3.03
2.93
g/l
0.09
27
242
33
337
0.98
0.01
1.8
1.4
0.39
0.37
g/l
0.10
27
240
2850
28494
1.00
0.00
5.8
5.3
2.75
2.80
mmol/l
2.47
2719
27007
19
191
0.99
0.00
4.1
2.8
42.75
43.19
%
0.03
12
93
20
199
1.01
0.00
1.5
1.5
15.82
23.34
umol/l
1.01
20
185
37
371
1.00
0.00
1.2
1.4
606.10
362.11
pmol/l
0.61
31
320
34
338
1.01
0.00
1.7
1.4
6.61
6.64
g/l
0.02
28
242
11
111
0.99
0.00
1.3
1.5
96.71
91.00
nmol/24h
0.09
11
111
11
114
0.96
0.00
1.3
1.7
—
—
—
0
0
26
263
0.99
0.00
1.1
1.2
—
62.86
—
0
7
250
2503
1.00
0.00
4.9
5.0
0.17
0.11
%
0.36
60
661
14
143
0.98
0.00
1.1
1.1
—
—
—
0
0
19
193
0.98
0.00
2.2
2.5
690.91
620.82
ml
0.25
11
133
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.0
92.74
74.88
ug/l
—
5
44
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
383.56
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.03
—
0
7
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.8
—
2.42
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
1.4
1.6
65.86
61.41
%
—
7
64
0
7
0.00
-0.00
0.0
1.1
—
37.13
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
2.4
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1148.13
—
0
8
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
2.92
—
0
5
5
50
1.00
-0.00
2.0
3.2
3458.40
3061.27
u/l
—
5
45
0
6
0.00
-0.00
0.0
1.2
—
68.97
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
2800.00
—
0
5
8
88
0.91
-0.00
1.3
1.2
—
—
—
0
0
8
84
0.95
-0.00
1.8
2.1
—
175.17
—
0
11

Mortality – FinRegistry

Association

Association between endpoint H7_DIVERGSTRAB and mortality.

Females

Parameter HR [95% CI] p-value
H7_DIVERGSTRAB 1.402 [1.2, 1.63] < 0.001
Birth year 0.994 [0.99, 1.0] 0.189

During the follow-up period (1.1.1998 — 31.12.2019), 367 out of 5205 females with H7_DIVERGSTRAB died.

Males

Parameter HR [95% CI] p-value
H7_DIVERGSTRAB 1.47 [1.26, 1.71] < 0.001
Birth year 0.989 [0.98, 1.0] 0.019

During the follow-up period (1.1.1998 — 31.12.2019), 424 out of 4879 males with H7_DIVERGSTRAB died.

Mortality risk

Mortality risk for people of age

years, who have H7_DIVERGSTRAB.

N-year risk Females Males
1 0.126% 0.247%
5 0.883% 1.752%
10 1.992% 4.215%
15 3.76% 8.247%
20 6.617% 14.032%

Relationships between endpoints

Index endpoint: H7_DIVERGSTRAB – Divergent concomitant strabismus

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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