Optic atrophy

H7_OPTIC_ATROPHY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H47.2
  • Cause of death: ICD-10 H47.2

2 out of 7 registries used, show all original rules.

723

4. Check minimum number of events

None

723

5. Include endpoints

None

723

6. Filter based on genotype QC (FinnGen only)

652

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 652 360 292
Unadjusted period prevalence (%) 0.13 0.13 0.13
Median age at first event (years) 55.77 55.37 56.26

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
681
Matched controls
6810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H47.2
ICD-10 Finland
Optic atrophy
+∞
307.7
681
*
XCK00
NOMESCO Finland
Perimetry
20.2
280.1
250
190
H53.4
ICD-10 Finland
Visual field defects
25.8
174.3
127
60
CS494
NOMESCO Finland
Other visual field testing
20.3
145.2
117
69
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
8.7
135.0
208
327
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
17.1
131.9
116
81
H46
ICD-10 Finland
Optic neuritis
43.0
131.9
80
21
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
42.6
125.1
76
20
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
32.4
106.6
70
24
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
43.3
104.3
63
16
G35
ICD-10 Finland
Multiple sclerosis
23.9
96.9
71
33
H47.1
ICD-10 Finland
Papilloedema, unspecified
37.9
94.4
59
17
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
8.1
92.7
140
210
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
11.6
92.5
102
102
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
27.7
91.1
63
25
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.7
79.4
265
819
N86
ICPC
Multiple sclerosis
49.3
78.6
46
10
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
49.3
78.6
46
10
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
5.7
76.0
171
380
109
Kela drug reimbursment
Multiple sclerosis
27.5
73.8
51
20
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.5
71.8
167
381
XCD10
NOMESCO Finland
Electrophysiological examination of eye
12.9
71.6
72
62
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
7.3
68.8
111
177
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
22.9
60.9
45
21
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
91.3
60.1
66
8
XCK10
NOMESCO Finland
Photography of fundus of eye
5.0
56.0
141
340
101
Kela drug reimbursment
Anterior pituitary hypofunction
20.8
55.9
43
22
N03AX14
ATC
levetiracetam; systemic
9.5
54.7
68
79
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.7
54.5
150
388
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
10.3
52.0
60
63
TAB00
NOMESCO Finland
Lumbar puncture
6.4
50.9
91
160
AA1AD
NOMESCO Finland
CT of head and brain
3.3
50.1
297
1288
Z3229
NOMESCO Finland
Other healthcare associate professional
4.7
49.6
132
331
H02AB09
ATC
hydrocortisone; systemic
8.6
45.9
61
77
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
9.0
41.7
53
63
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
16.7
41.2
35
22
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
10.6
40.2
45
45
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
14.6
39.3
36
26
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
8.9
39.0
50
60
E23.00
ICD-10 Finland
Panhypopituitarism
82.7
35.2
39
5
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
8.8
34.2
44
53
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.2
34.2
102
276
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.1
32.8
60
107
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
31.7
29.7
39
13
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.7
29.1
42
58
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.5
28.4
75
184
183
Kela drug reimbursment
Lamotrigin and topiramate
11.6
27.7
29
26
XA800
NOMESCO Finland
Neuropsychological investigation
4.4
26.3
70
173
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
26.3
25.5
35
14
N03AG01
ATC
valproic acid; systemic, rectal
3.8
24.1
78
222
H47.3
ICD-10 Finland
Other disorders of optic disc
39.1
24.1
30
8
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
20.4
23.7
35
18
N03AF02
ATC
oxcarbazepine; oral
5.1
23.5
51
106
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.9
23.2
126
494
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
31.3
23.0
30
10
SPAT1229
SPAT
Assessment of need for aid
3.6
22.3
78
234
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
19.7
21.5
32
17
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
18.6
21.0
32
18
G91.0
ICD-10 Finland
Communicating hydrocephalus
25.2
21.0
29
12
H53.2
ICD-10 Finland
Diplopia
5.2
20.7
44
90
H54.7
ICD-10 Finland
Unspecified visual loss
23.2
20.5
29
13
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
20.3
158
739
G91.1
ICD-10 Finland
Obstructive hydrocephalus
28.0
20.2
27
10
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
41.4
19.6
24
6
M03BX01
ATC
baclofen; systemic
6.4
19.5
33
54
WX882
NOMESCO Finland
High dependency care
4.4
19.5
51
124
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
19.2
139
627
3400A
ICD-9 Finland
Multiple sclerosis[SCLEROSIS MULTIPLEX (DISSEMINATA)]
+∞
18.8
18
*
102
Kela drug reimbursment
Diabetes insipidus
195.2
18.6
19
*
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
37.8
17.7
22
6
H54.1
ICD-10 Finland
Severe visual impairment, binocular
184.6
17.6
18
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
17.1
147
713
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
36.0
16.8
21
6
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.1
16.6
29
49
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
5.5
16.5
32
60
N05BA09
ATC
clobazam; oral
14.7
16.4
27
19
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
41.2
16.4
20
5
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.7
16.3
26
40
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
16.2
91
360
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
17.2
16.2
25
15
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
48.7
16.1
19
*
N05CD08
ATC
midazolam; nasal, systemic
5.0
16.1
35
73
N04BB01
ATC
amantadine; oral
12.1
15.7
28
24
L03AB07
ATC
interferon beta-1a; parenteral
22.7
15.6
22
10
N03AX18
ATC
lacosamide; systemic
14.2
15.6
26
19
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
163.6
15.5
16
*
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.7
15.3
50
143
H54.4
ICD-10 Finland
Blindness, monocular
25.7
14.8
20
8
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.8
14.7
78
299
H54.0
ICD-10 Finland
Blindness, binocular
+∞
14.6
14
*
Z2445
NOMESCO Finland
Psychologist
3.3
14.1
54
171
A06AD11
ATC
lactulose; oral
2.3
13.7
119
577
G93.2
ICD-10 Finland
Benign intracranial hypertension
76.7
13.6
15
*
N03AF01
ATC
carbamazepine; oral, rectal
3.3
13.6
52
165
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.7
13.5
76
300
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
142.7
13.5
14
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
5.2
13.5
28
56
N03AE01
ATC
clonazepam; systemic
3.3
13.3
51
162
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.1
13.2
56
189
L03AX13
ATC
glatiramer acetate; parenteral
29.0
13.0
17
6
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
5.0
12.9
28
58
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
23.1
12.9
18
8
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
12.8
116
571
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.3
12.8
26
51
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
17.7
12.6
19
11
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
17.7
12.6
19
11
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
12.5
297
2039
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.6
12.4
42
123
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
12.3
116
580
N03AX16
ATC
[U] pregabalin
2.0
12.3
168
966
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.9
12.2
58
209
N03AX11
ATC
topiramate; oral
4.3
12.1
31
74
R35
ICD-10 Finland
Polyuria
2.8
11.9
62
235
N05BA01
ATC
diazepam; systemic, rectal
2.2
11.9
106
518
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
11.9
127
667
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.5
11.8
42
127
L28
ICPC
Limited function/disability (L)
2.0
11.5
142
786
34099
ICD-8 Finland
Multiple sclerosis
122.0
11.5
12
*
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
15.4
11.4
18
12
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
9.1
11.3
23
26
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
13.0
11.2
19
15
H34.1
ICD-10 Finland
Central retinal artery occlusion
20.4
11.2
16
8
SPAT1216
SPAT
Assessment of functional ability
2.1
11.0
117
613
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
44.1
10.9
13
*
ZXC95
NOMESCO Finland
Use of surgical navigator
8.5
10.9
23
28
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
13.2
10.7
18
14
ZXD05
NOMESCO Finland
Urgent procedure
1.8
10.7
214
1384
E23.05
ICD-10 Finland
Lack of TSH
61.0
10.7
12
*
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
11.5
10.6
19
17
F02.89*G35
ICD-10 Finland
Dementia in multiple sclerosis
111.7
10.4
11
*
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
10.4
10
*
H01AC01
ATC
somatropin; parenteral
8.4
10.4
22
27
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
8.4
10.4
22
27
-, ,
ICD-10 Finland
4.5
10.3
25
57
P85
ICPC
Mental retardation
13.4
10.2
17
13
N03AX09
ATC
lamotrigine; oral
2.9
10.1
47
168
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.3
10.0
38
120
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
40.7
10.0
12
*
N03AB02
ATC
phenytoin; systemic
5.3
9.9
20
39
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
9.9
69
303
ZXA10
NOMESCO Finland
Bilateral
1.9
9.8
138
795
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
20.4
9.8
14
7
Z2446
NOMESCO Finland
Social worker
2.4
9.8
67
291
XKD00
NOMESCO Finland
Uroflowmetry
2.1
9.8
104
543
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.0
9.8
28
73
D35.30
ICD-10 Finland
Craniopharyngoma
55.8
9.7
11
*
L04AA27
ATC
[U] fingolimod
55.8
9.7
11
*
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
9.7
60
249
H50.1
ICD-10 Finland
Divergent concomitant strabismus
11.6
9.6
17
15
SPAT1172
SPAT
Guidance concerning hydration
4.9
9.6
21
44
H26.4
ICD-10 Finland
After-cataract
2.3
9.6
76
353
G04BD07
ATC
tolterodine; oral
3.0
9.6
42
145
OAB43, ,
SPAT
0.5
9.5
71
1399
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.3
9.4
24
57
Z3231
NOMESCO Finland
Registered nurse
1.7
9.4
203
1332
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
101.4
9.4
10
*
E22.80
ICD-10 Finland
Central precocious puberty
101.4
9.4
10
*
2132
FHL
Ventricular operators sunt
101.4
9.4
10
*
ZXC86
NOMESCO Finland
Use of endoscopic device
17.8
9.4
14
8
3771A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic atrophy
+∞
9.4
9
*
37790
ICD-8 Finland
Other diseases of retina and optic nerve, Atrophia (et degeneratio) nervi optici (tabica excepta)
+∞
9.4
9
*
SPAT1234
SPAT
Support of social functional capacity
3.0
9.3
42
147
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
9.3
68
304
114
Kela drug reimbursment
Glaucoma
2.4
9.3
67
298
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.5
9.3
32
95
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
9.3
324
2417
R51.80
ICD-10 Finland
Headache
1.9
9.2
124
704
SPAT1254
SPAT
Administration of medicine
2.0
9.2
109
592
L04AX01
ATC
azathioprine; systemic
3.1
9.0
38
128
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
9.0
225
1536
L03AB08
ATC
interferon beta-1b; parenteral
24.4
8.9
12
5
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
24.4
8.9
12
5
N18
ICPC
Paralysis/weakness
4.4
8.9
22
51
G81.9
ICD-10 Finland
Hemiplegia, unspecified
8.1
8.9
19
24
H54.5
ICD-10 Finland
Severe visual impairment, monocular
12.7
8.9
15
12
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
12.7
8.9
15
12
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.1
8.8
36
119
A28
ICPC
Limited function/disability NOS
1.9
8.8
131
768
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
8.8
259
1843
XKC03
NOMESCO Finland
Water cystometry
3.5
8.7
30
89
G81.1
ICD-10 Finland
Spastic hemiplegia
50.7
8.7
10
*
AA1AA
NOMESCO Finland
Head X-ray examination
7.1
8.6
20
29
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
8.6
95
503
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
8.6
193
1278
G91.8
ICD-10 Finland
Other hydrocephalus
27.9
8.5
11
*
164
Kela drug reimbursment
Fingolimod
27.9
8.5
11
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
8.5
251
1785
E23.2
ICD-10 Finland
Diabetes insipidus
91.1
8.4
9
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
8.3
52
217
F83
ICD-10 Finland
Mixed specific developmental disorders
6.6
8.2
20
31
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
14.7
8.2
13
9
G04BD09
ATC
trospium; oral
4.0
8.2
23
59
R4120
NOMESCO Finland
Occupational therapy
2.3
8.2
60
269
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
4.6
8.2
19
42
H03AA01
ATC
levothyroxine sodium; systemic
1.8
8.1
157
995
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
8.1
49
201
CS2P4
NOMESCO Finland
Optic nerve head imaging
9.1
8.1
16
18
ZXA00
NOMESCO Finland
Right side
1.7
8.1
180
1186
H53.0
ICD-10 Finland
Amblyopia ex anopsia
6.4
8.1
20
32
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
8.0
90
478
L04AA06
ATC
mycophenolic acid; systemic
4.2
8.0
21
51
H40.11
ICD-10 Finland
Low pressure glaucoma
4.2
8.0
21
51
H25.8
ICD-10 Finland
Other senile cataract
2.1
8.0
75
372
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.5
7.9
19
43
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
6.7
7.9
19
29
N99
ICPC
Neurological disease other
6.7
7.9
19
29
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
7.9
7.9
17
22
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
7.9
7.9
17
22
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
13.2
7.9
13
10
G40.89
ICD-10 Finland
Other epilepsy
13.2
7.9
13
10
S01ED01
ATC
timolol; ophthalmic
3.4
7.9
28
85
PAW37
NOMESCO Finland
Biopsy of temporal artery
11.0
7.8
14
13
PA2AD
NOMESCO Finland
CT angiography of brain
9.6
7.8
15
16
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
15.2
7.7
12
8
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.0
7.7
20
34
H48.1*G35
ICD-10 Finland
Retrobulbar neuritis in multiple sclerosis
45.5
7.7
9
*
36703
ICD-8 Finland
Inflammation of optic nerve and retina, Neuritis optica, retrobulbaris
45.5
7.7
9
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
6.8
7.6
18
27
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
8.2
7.6
16
20
R3120
NOMESCO Finland
Training in mobility skills
18.6
7.6
11
6
301
Kela drug reimbursment
Growth hormone
12.0
7.6
13
11
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
25.3
7.6
10
*
G93.0
ICD-10 Finland
Cerebral cysts
25.3
7.6
10
*
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
9.0
7.6
15
17
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
9.0
7.6
15
17
A02BC03
ATC
lansoprazole; oral
1.7
7.5
185
1247
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.7
7.5
40
154
G40
ICD-10 Finland
Epilepsy
6.6
7.4
18
28
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
80.9
7.4
8
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
80.9
7.4
8
*
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.2
7.3
19
46
G40.10
ICD-10 Finland
Simple partial seizures
9.5
7.3
14
15
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
9.5
7.3
14
15
74200
ICD-8 Finland
Congenital hydrocephalus, Communicans
+∞
7.3
7
*
C72.3
ICD-10 Finland
Malignant neoplasm: Optic nerve
+∞
7.3
7
*
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
7.3
99
562
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.8
7.3
37
139
R42
ICD-10 Finland
Dizziness and giddiness
1.7
7.3
154
998
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
7.2
91
503
RD210, ,
NOMESCO Finland
3.8
7.2
22
60
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
7.2
235
1697
353
Kela drug reimbursment
Cladribine and fingolimod
30.4
7.2
9
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
30.4
7.2
9
*
L04AA31
ATC
[U] teriflunomide
30.4
7.2
9
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
30.4
7.2
9
*
RS140, ,
NOMESCO Finland
20.3
7.1
10
5
XCH05
NOMESCO Finland
Eye pressure longterm registration
8.0
7.1
15
19
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.1
7.1
29
96
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.7
7.1
19
34
G41.9
ICD-10 Finland
Status epilepticus, unspecified
12.2
7.1
12
10
N28
ICPC
Limited function/disability (N)
4.3
7.0
18
43
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
7.0
111
660
S00.0
ICD-10 Finland
Superficial injury of scalp
3.5
7.0
24
71
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
6.9
183
1255
N29
ICPC
Neurological sympt/complt other
4.2
6.8
18
44
RS222, ,
NOMESCO Finland
6.8
6.8
16
24
WF099
NOMESCO Finland
Other radiotherapy
11.1
6.8
12
11
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.8
6.8
118
722
H50.31
ICD-10 Finland
Intermittent exotropia
4.3
6.8
17
40
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
40.5
6.8
8
*
H52.1
ICD-10 Finland
Myopia
2.8
6.8
34
127
R32
ICD-10 Finland
Unspecified urinary incontinence
3.3
6.8
25
78
SPAT1255
SPAT
Intravenous administration of medicine
2.4
6.7
44
188
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
22.8
6.7
9
*
Z02.7
ICD-10 Finland
Issue of medical certificate
2.2
6.7
58
280
R62.0
ICD-10 Finland
Delayed milestone
5.6
6.6
18
33
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.6
6.6
18
33
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
7.9
6.6
14
18
H52.0
ICD-10 Finland
Hypermetropia
3.2
6.6
25
79
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.3
6.6
51
234
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.5
6.6
22
64
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.5
6.6
22
64
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
12.4
6.6
11
9
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
12.4
6.6
11
9
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.1
6.5
63
317
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
6.5
89
507
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
70.5
6.4
7
*
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
70.5
6.4
7
*
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
70.5
6.4
7
*
N06AX21
ATC
duloxetine; oral
1.9
6.4
81
448
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.2
6.4
51
237
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
14.5
6.4
10
7
N03AX12
ATC
[U] gabapentin; oral
1.8
6.4
110
671
S01EE04
ATC
travoprost; ophthalmic
4.1
6.4
17
42
H53.8
ICD-10 Finland
Other visual disturbances
4.1
6.4
17
42
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
6.3
199
1417
W19
ICD-10 Finland
Unspecified fall
2.0
6.3
74
400
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
18.2
6.3
9
5
G04BD04
ATC
oxybutynin; oral, transdermal
2.4
6.3
44
194
7423A
ICD-9 Finland
Other congenital anomalies of nervous system, Congenital hydrocephalus
+∞
6.3
6
*
AAK00
NOMESCO Finland
Cranioplasty
+∞
6.3
6
*
E23.0
ICD-10 Finland
Hypopituitarism
+∞
6.3
6
*
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
+∞
6.3
6
*
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
7.1
6.2
14
20
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
6.2
77
424
S01ED51
ATC
timolol, combinations; ophthalmic
2.1
6.2
55
268
H02.4
ICD-10 Finland
Ptosis of eyelid
3.1
6.1
25
83
L04AX07
ATC
dimethyl fumarate; oral
12.7
6.1
10
8
N06AX16
ATC
venlafaxine; oral
1.8
6.1
97
578
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.1
111
688
N88
ICPC
Epilepsy
8.7
6.1
12
14
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
6.1
87
502
R4130
NOMESCO Finland
Speech therapy
2.9
6.0
27
95

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
72
127
6.22
39.92
2.0
1.9
—
—
—
0
0
78
158
5.45
37.32
1.6
1.9
611.89
453.96
mg/l
0.66
72
148
48
62
8.25
35.29
1.8
2.0
—
—
—
0
0
69
140
5.37
32.87
1.5
1.8
3.73
3.69
mmol/l
0.09
64
131
66
137
5.23
30.61
1.9
1.8
21.83
17.38
e6/l
0.10
52
103
66
138
5.19
30.36
2.0
1.9
1226.19
967.16
e6/l
0.09
52
107
45
73
6.53
26.94
2.1
2.4
—
—
—
0
0
38
57
7.00
24.46
3.5
1.3
1038.21
277.60
mu/l
0.60
33
45
30
45
6.93
19.27
1.2
1.1
246.28
207.29
mg/l
0.73
25
38
40
81
5.18
18.99
1.2
1.2
—
—
—
0
0
141
651
2.47
18.46
3.8
2.0
375.15
366.38
nmol/l
0.06
131
615
398
2776
2.04
18.10
11.8
7.5
1.21
1.21
mmol/l
1.05
373
2580
26
37
7.27
17.49
1.3
1.1
0.86
0.50
ratio
2.08
16
18
42
96
4.60
17.30
4.7
6.1
431.20
365.84
umol/l
1.35
35
89
422
3066
1.99
16.40
11.1
7.9
1.21
1.21
mmol/l
0.02
381
2688
282
1815
1.95
15.38
2.7
2.2
187.26
202.65
u/l
0.24
265
1730
236
1434
1.99
15.19
2.9
2.4
—
—
—
0
0
169
936
2.07
13.91
2.3
2.2
29.06
29.40
s
0.38
163
907
39
104
3.92
13.16
2.2
1.5
24.25
25.60
ng/l
0.09
39
104
454
3522
1.87
12.91
8.3
5.7
6.68
6.64
mmol/l
0.14
442
3343
59
214
2.92
12.30
2.7
1.6
6.57
8.77
u/l
0.68
43
165
106
520
2.23
11.77
4.1
2.7
9.85
10.36
g/l
0.67
97
481
155
879
1.99
11.74
7.0
6.3
1.01
1.08
mmol/l
1.97
146
821
354
2598
1.76
11.60
6.8
5.3
35.25
35.93
g/l
1.32
329
2451
262
1773
1.78
11.32
4.5
3.2
—
—
—
0
0
135
739
2.03
11.26
2.0
1.6
—
—
—
0
0
476
3829
1.81
11.10
7.4
4.6
4910.17
2378.43
e6/l
—
6
60
23
28
8.46
10.88
1.3
1.1
145.09
145.87
nmol/l
0.02
23
28
241
1610
1.77
10.77
6.9
4.4
—
—
—
0
0
139
2254
0.52
10.76
3.2
3.1
—
—
—
0
0
102
513
2.16
10.61
4.7
4.4
7.31
7.34
ph
0.44
79
380
130
717
2.00
10.57
9.9
9.7
7.42
7.42
ph
0.21
73
405
405
3136
1.72
10.53
8.1
6.9
10.80
12.79
umol/l
2.46
379
2986
128
710
1.99
10.22
10.0
9.8
0.45
0.91
mmol/l
0.56
107
587
271
1894
1.72
10.19
3.2
2.4
—
—
—
0
0
342
2553
1.68
9.99
5.8
3.5
6.56
6.21
ph
5.12
178
1443
116
628
2.02
9.90
13.6
10.5
—
—
—
0
0
20
24
8.55
9.61
1.1
1.0
1810.75
1425.42
miu/ml
0.61
20
24
527
4447
1.82
9.59
10.4
8.2
86.74
81.97
u/l
0.96
491
4223
84
407
2.21
9.56
2.7
2.5
10.00
20.15
au/ml
—
5
38
168
1052
1.79
9.14
4.9
4.0
0.83
0.82
mmol/l
0.58
162
1000
396
3154
1.61
8.33
11.0
6.6
0.61
0.58
e9/l
1.71
351
2698
20
31
6.61
8.23
4.9
3.5
0.19
0.52
e9/l
1.19
14
14
18
24
7.67
8.20
3.1
3.6
28.90
34.32
umol/l
0.61
12
17
396
3163
1.60
8.15
11.1
6.6
0.04
0.04
e9/l
0.78
350
2709
15
15
10.20
8.06
1.3
1.0
—
—
—
0
0
284
2101
1.60
8.06
10.7
6.5
—
—
—
0
0
405
3263
1.60
7.95
11.5
6.9
0.19
0.20
e9/l
0.65
359
2843
332
2561
1.58
7.81
2.2
2.1
94.78
95.98
pmol/l
0.18
186
1367
399
3218
1.58
7.68
11.2
6.6
1.93
1.99
e9/l
0.43
357
2831
76
390
2.07
7.45
7.7
5.4
—
—
—
0
0
147
949
1.70
7.01
1.8
1.7
1232.43
1201.21
nmol/l
0.15
112
741
341
2690
1.54
6.98
3.3
2.6
77.54
76.67
nmol/l
0.21
305
2453
366
2934
1.53
6.94
10.6
6.6
57.22
56.25
%
0.78
353
2819
425
3520
1.55
6.94
14.0
9.9
4.42
4.04
e9/l
2.15
377
3050
116
702
1.79
6.94
8.7
5.2
1.63
1.70
mmol/l
0.07
103
594
85
466
1.94
6.93
2.9
2.7
66.54
66.90
g/l
0.18
79
437
163
1088
1.65
6.83
3.8
3.1
1.18
0.85
e6/l
0.66
90
562
78
418
1.98
6.79
3.2
1.7
0.92
1.35
g/l
2.32
73
388
21
60
3.58
6.48
3.1
2.7
42.62
38.70
%
0.55
21
60
83
466
1.89
6.30
2.4
2.4
4.12
7.21
ug/l
2.50
68
414
360
2913
1.50
6.29
11.3
6.8
8.97
8.79
%
0.55
346
2752
94
552
1.82
6.19
2.7
2.1
0.18
0.04
estimate
0.33
11
120
116
726
1.72
6.14
8.8
5.1
7.37
7.38
ph
0.47
75
425
232
1730
1.52
5.92
6.9
4.0
0.00
0.00
estimate
0.74
48
603
115
727
1.70
5.86
8.9
5.1
5.76
5.77
kpa
0.04
115
708
226
1681
1.52
5.82
1.9
1.7
19.16
20.04
nmol/l
0.39
191
1424
10
9
11.25
5.81
1.6
1.1
—
—
—
0
0
516
4543
1.56
5.74
5.6
4.3
14.94
14.75
pmol/l
0.93
475
4179
471
4067
1.51
5.73
7.1
4.5
—
2.70
—
0
8
383
3177
1.47
5.66
6.4
3.9
0.00
2.90
estimate
0.50
55
648
355
2902
1.47
5.66
11.4
6.8
0.67
0.68
%
0.14
341
2731
47
224
2.18
5.60
1.2
1.3
—
—
—
0
0
628
5832
1.99
5.57
29.7
18.7
139.57
139.66
mmol/l
0.33
616
5732
103
642
1.71
5.52
8.0
4.6
5.26
4.62
kpa
2.29
103
624
355
2911
1.46
5.52
11.3
6.7
2.84
2.96
%
0.48
341
2745
628
5840
1.97
5.42
29.4
18.8
3.95
3.97
mmol/l
1.33
613
5722
109
695
1.68
5.37
3.6
3.2
1.83
1.75
%
0.46
100
634
361
2980
1.45
5.35
11.1
6.7
28.08
28.60
%
0.37
352
2845
56
293
1.99
5.24
3.1
2.2
0.00
0.01
estimate
—
8
98
88
533
1.75
5.22
2.5
3.1
75.19
69.06
e9/l
0.87
57
397
193
1426
1.49
5.02
7.7
3.9
1.02
1.02
kg/l
0.18
134
953
381
3201
1.43
4.99
6.4
3.9
0.00
0.51
estimate
0.52
55
611
210
1580
1.48
4.98
2.7
2.4
3.11
2.87
mg/l
0.87
182
1366
375
3144
1.43
4.96
6.3
3.9
0.02
0.00
estimate
0.44
54
638
327
2675
1.43
4.96
15.5
13.6
1.25
1.24
inr
0.14
255
2220
79
472
1.76
4.91
5.4
4.6
81.07
79.28
ng/l
0.06
72
430
128
869
1.58
4.89
2.6
2.1
—
—
—
0
0
84
513
1.73
4.84
8.0
5.1
7.41
7.41
ph
0.10
73
417
215
1640
1.45
4.71
4.2
3.3
—
0.00
estimate
—
0
8
38
741
0.48
4.68
1.6
1.6
—
—
—
0
0
183
1355
1.48
4.66
3.4
2.8
6.09
5.05
e6/l
0.53
172
1242
96
615
1.65
4.64
2.7
2.7
0.20
0.21
g/l
0.57
90
582
224
1732
1.44
4.54
4.2
3.4
0.36
0.35
e6/l
0.04
169
1268
62
354
1.83
4.49
3.0
3.6
4.27
4.65
pmol/l
1.34
56
321
252
1994
1.42
4.48
4.6
3.5
262.69
74.69
e6/l
0.39
196
1522
89
569
1.65
4.33
3.5
2.4
33.00
124.72
u/l
0.55
72
476
10
16
6.33
4.30
2.2
1.9
26.34
16.98
umol/l
—
10
16
282
2288
1.40
4.29
5.5
4.2
53.71
97.83
e6/l
1.27
200
1593
80
499
1.68
4.28
1.7
1.4
—
—
—
0
0
325
2711
1.38
4.14
3.2
2.8
—
—
estimate
—
0
0
12
26
4.68
4.07
1.3
1.1
—
—
—
0
0
272
2231
1.36
3.74
4.2
3.8
52.13
76.36
ng/l
0.27
220
1567
613
5766
1.63
3.64
24.8
15.8
27.90
23.30
mg/l
2.23
533
4685
83
547
1.59
3.59
4.4
2.4
12.58
13.05
nmol/l
0.22
76
496
232
1868
1.37
3.55
8.8
6.5
—
—
—
0
0
226
1820
1.36
3.44
6.5
3.9
7.40
7.40
ph
0.25
169
1304
13
37
3.56
3.41
5.5
3.2
1.74
1.81
umol/l
0.09
13
31
229
1850
1.36
3.41
2.7
2.6
53.42
63.25
u/l
1.28
210
1726
43
241
1.84
3.35
1.7
2.1
1.63
1.47
g/l
0.48
37
218
252
2083
1.33
3.18
3.3
3.5
2.37
2.36
mmol/l
0.30
221
1897
18
73
2.51
3.15
7.8
4.2
—
—
—
0
0
574
5363
1.45
3.09
6.1
5.3
1.92
1.91
mu/l
0.09
523
4985
13
41
3.21
3.07
2.5
3.0
387.54
919.98
mg
1.53
13
41
136
1025
1.41
3.06
4.0
3.3
2.41
1.81
e6/l
0.39
60
501
121
894
1.43
3.04
2.6
2.6
20.88
22.20
%
0.44
110
841
24
467
0.50
2.97
1.5
1.8
3.34
3.48
mmol/l
0.27
17
340
635
6071
1.68
2.96
29.8
20.2
74.28
75.65
umol/l
0.42
627
6009
128
963
1.41
2.90
2.6
2.6
2.26
2.35
g/l
0.88
114
893
31
549
0.54
2.85
1.3
1.4
—
—
—
0
0
12
39
3.11
2.78
4.0
1.8
17.81
19.77
umol/l
0.10
12
33
134
1029
1.38
2.69
2.7
2.6
12.02
13.12
umol/l
0.91
120
961
36
207
1.78
2.63
6.5
4.1
1.40
1.32
mmol/l
0.22
36
202
10
30
3.37
2.61
3.1
1.9
179.60
120.93
ng/l
—
10
24
7
15
4.70
2.60
3.9
2.2
1.19
1.14
umol/l
—
7
8
150
1182
1.35
2.55
3.6
3.0
547.25
544.42
mosm/kgh2o
0.06
130
1041
212
1759
1.30
2.50
3.5
3.4
1313.74
1263.91
ng/l
0.07
185
1503
629
6034
1.56
2.45
17.4
12.0
28.01
26.40
u/l
0.66
609
5890
16
71
2.28
2.36
1.3
1.2
—
—
—
0
0
20
98
2.07
2.33
1.4
1.2
2.57
3.95
u/ml
—
7
44
7
18
3.92
2.25
2.6
1.7
—
—
—
0
0
14
60
2.36
2.23
2.6
3.3
3.44
6.26
nmol/l
0.48
14
60
11
41
2.71
2.21
6.5
2.8
26.18
27.89
umol/l
0.29
11
36
8
24
3.36
2.18
1.9
1.2
165.63
187.19
mmol/24h
—
8
24
8
24
3.36
2.18
1.5
1.4
—
—
—
0
0
146
1172
1.31
2.17
3.2
2.9
2.46
2.45
mmol/l
0.69
126
1052
9
30
3.03
2.15
44.4
37.0
7.37
7.17
ug/l
—
9
24
9
31
2.93
2.08
3.9
3.1
371.89
665.52
u/ml
—
9
31
0
55
0.00
2.07
0.0
3.9
—
15.81
—
0
41
261
2264
1.25
2.07
2.5
2.1
—
—
—
0
0
7
20
3.52
2.06
1.1
1.5
722.43
68.25
nmol/24h
—
7
20
6
15
4.03
2.04
3.3
1.5
28.17
32.13
%
—
6
15
461
4935
0.80
2.03
28.7
19.6
13.83
13.57
%
3.53
454
4896
94
716
1.36
1.99
5.5
3.1
7.69
7.45
umol/l
0.06
85
633
100
770
1.35
1.98
2.0
1.5
—
—
—
0
0
17
84
2.05
1.97
1.1
1.2
—
—
—
0
0
7
21
3.36
1.97
8.3
3.7
—
—
—
0
0
111
874
1.32
1.90
1.4
1.3
400.00
445.10
titre
0.21
21
196
11
237
0.46
1.88
1.3
1.6
938.95
981.67
mu/l
0.08
11
197
8
28
2.88
1.86
2.4
2.3
112.88
86.02
ug/l
—
8
28
269
2365
1.23
1.84
6.5
3.8
0.02
0.03
estimate
0.07
46
532
46
313
1.50
1.81
2.9
1.5
19.45
24.70
iu/l
0.53
37
255
53
372
1.46
1.80
3.4
2.3
—
—
—
0
0
12
54
2.24
1.74
1.6
2.7
—
—
—
0
0
28
172
1.65
1.70
1.4
1.2
—
—
—
0
0
97
765
1.31
1.65
3.9
3.4
4.86
5.76
e9/l
0.49
80
677
36
240
1.53
1.58
3.8
5.6
449.43
280.89
mg/l
0.25
14
127
14
71
1.99
1.55
2.3
1.3
—
—
—
0
0
5
15
3.35
1.52
1.8
2.3
—
—
—
0
0
29
188
1.57
1.45
1.4
1.4
312.56
294.08
ug/g
0.14
14
114
56
416
1.38
1.43
1.3
1.3
120.65
162.02
u/ml
0.34
22
165
231
2050
1.19
1.36
5.0
3.4
38.55
32.21
u/l
0.52
218
1951
113
937
1.25
1.31
1.7
1.6
—
—
—
0
0
47
630
0.73
1.31
1.5
1.7
—
—
—
0
0
24
153
1.59
1.30
6.9
2.8
1.09
2.09
ratio
1.72
15
89
564
5420
1.24
1.30
5.6
5.0
5.86
5.94
mmol/l
0.78
513
5019
13
69
1.90
1.29
1.0
1.2
—
—
—
0
0
610
5916
1.30
1.29
20.9
13.8
—
—
—
0
0
5
18
2.79
1.28
5.4
2.6
0.69
0.61
mmol/l
—
5
18
27
179
1.53
1.25
17.1
10.6
—
—
—
0
0
17
100
1.72
1.24
1.4
1.7
—
—
—
0
0
17
100
1.72
1.24
1.4
1.7
—
—
—
0
0
17
100
1.72
1.24
1.4
1.7
—
—
—
0
0
17
100
1.72
1.24
1.4
1.7
—
—
—
0
0
36
255
1.43
1.22
2.5
1.8
—
—
—
0
0
10
49
2.06
1.22
3.4
2.3
—
—
—
0
0
160
1387
1.20
1.21
2.1
1.5
2.03
2.37
g/l
1.95
104
817
304
2785
1.17
1.19
13.2
11.2
0.00
0.00
e9/l
0.39
247
2275
38
274
1.41
1.18
1.2
2.0
0.86
7.58
iu/ml
—
5
70
15
247
0.60
1.16
1.1
1.1
—
—
—
0
0
59
459
1.31
1.15
3.4
2.3
6.12
6.10
ph
0.06
29
308
18
111
1.64
1.13
1.7
1.9
—
—
—
0
0
22
143
1.56
1.12
3.5
1.9
—
—
—
0
0
8
40
2.01
1.12
5.6
2.5
19.13
35.90
mg/l
—
8
30
25
168
1.51
1.11
3.7
3.4
1.14
2.31
index
1.06
14
101
5
21
2.39
1.09
4.0
2.1
40.80
41.32
g/l
—
5
21
53
410
1.32
1.08
7.0
4.6
129.42
129.17
g/l
0.03
53
402
13
74
1.77
1.07
6.4
7.2
13.55
11.10
%
1.75
13
74
154
1347
1.19
1.06
2.0
1.8
1.33
1.29
mg/l
0.07
116
1047
216
1946
1.16
1.03
3.9
3.6
—
0.71
—
0
7
641
6284
1.34
1.02
37.1
24.0
7.00
6.74
e9/l
2.45
627
6155
58
460
1.29
1.00
1.5
1.6
—
—
—
0
0
24
165
1.47
0.98
3.1
1.9
2.72
4.45
iu/l
—
6
59
129
1122
1.18
0.95
3.8
4.1
618.62
475.27
ng/l
0.14
97
857
194
1746
1.16
0.94
4.9
5.3
1.63
2.23
ug/l
1.69
172
1586
6
27
2.23
0.93
1.2
1.2
681.33
113.39
iu/ml
—
6
27
9
52
1.74
0.92
1.0
1.2
—
—
—
0
0
640
6282
1.31
0.92
37.2
23.9
257.54
251.42
e9/l
1.29
628
6168
13
207
0.62
0.91
1.0
1.1
1.47
1.54
g/l
0.47
13
207
62
503
1.26
0.91
4.8
5.0
0.58
0.48
%
0.23
26
163
640
6283
1.31
0.91
37.1
23.9
90.83
90.67
fl
0.33
632
6234
416
3947
1.14
0.91
5.3
3.4
58.86
47.90
u/l
1.33
392
3745
640
6284
1.31
0.90
37.1
23.9
4.44
4.51
e12/l
3.04
627
6157
640
6284
1.31
0.90
38.1
24.6
39.80
40.39
%
1.99
632
6229
640
6284
1.31
0.90
37.0
23.8
30.15
30.23
pg
0.46
632
6234
305
2842
1.13
0.87
3.4
3.1
119.70
117.77
ug/l
0.06
275
2670
640
6287
1.30
0.86
37.5
24.1
132.84
135.41
g/l
4.33
632
6236
383
4032
0.89
0.84
4.2
4.0
—
0.27
—
0
11
61
500
1.24
0.83
5.5
5.2
0.15
0.12
%
0.19
26
145
12
73
1.66
0.82
1.7
1.4
0.54
0.60
nmol/l
0.21
12
67
64
529
1.23
0.81
5.5
5.1
0.67
0.90
%
0.53
29
176
27
198
1.38
0.81
2.4
2.3
12417.72
5173.37
u/l
—
6
77
8
47
1.71
0.81
1.4
1.1
87.38
101.91
pmol/l
—
8
47
17
114
1.50
0.80
1.6
1.2
—
—
—
0
0
15
222
0.67
0.78
1.3
2.0
—
—
—
0
0
62
515
1.22
0.76
4.8
5.5
0.00
0.13
%
1.17
25
134
6
34
1.77
0.76
1.0
1.8
—
—
—
0
0
9
55
1.64
0.73
1.3
1.5
—
—
—
0
0
6
107
0.56
0.73
1.7
1.4
—
—
—
0
0
6
107
0.56
0.73
1.8
1.6
—
—
—
0
0
5
25
2.01
0.73
1.0
1.1
—
—
—
0
0
36
282
1.29
0.72
7.8
4.5
24.64
24.99
mmol/l
0.21
36
273
155
1711
0.88
0.72
4.3
3.2
0.00
0.06
estimate
0.60
40
519
16
109
1.48
0.71
3.7
2.9
2.23
2.29
mmol/l
—
9
72
37
463
0.79
0.70
3.6
3.8
—
—
—
0
0
19
135
1.42
0.69
1.6
1.2
—
—
—
0
0
10
61
1.65
0.69
1.3
1.1
—
—
—
0
0
5
28
1.79
0.66
4.4
2.4
—
—
—
0
0
15
213
0.70
0.65
1.1
1.1
0.89
0.90
g/l
0.12
15
213
21
154
1.38
0.65
1.4
1.5
238.08
274.90
u/ml
0.27
13
71
10
63
1.60
0.62
1.6
1.7
93.01
90.54
%
—
10
63
540
5531
0.89
0.62
5.3
4.9
1.41
1.46
mmol/l
1.67
500
5162
8
51
1.58
0.60
4.5
3.6
0.13
0.75
index
—
8
51
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
2.2
—
—
—
0
0
0
21
0.00
0.60
0.0
2.2
—
3803.70
—
0
10
8
52
1.54
0.59
3.1
2.5
—
—
—
0
0
0
22
0.00
0.59
0.0
2.1
—
896.13
—
0
16
10
64
1.57
0.59
1.4
1.3
—
—
nmol/l
—
0
0
8
53
1.52
0.58
1.0
1.2
—
—
—
0
0
8
53
1.52
0.58
1.3
1.4
—
—
—
0
0
7
113
0.62
0.58
1.0
1.1
—
—
—
0
0
35
283
1.25
0.58
2.2
2.5
—
—
—
0
0
22
285
0.76
0.56
2.1
1.7
—
—
—
0
0
33
405
0.81
0.55
1.2
1.2
—
—
—
0
0
92
1029
0.88
0.54
1.2
1.3
14.36
10.96
u/ml
0.13
30
401
11
74
1.49
0.53
1.0
1.3
—
98.12
—
0
6
199
1858
1.10
0.52
4.0
3.5
40.01
56.73
mg/l
0.87
129
1220
37
306
1.22
0.51
1.4
1.3
—
—
—
0
0
6
41
1.47
0.50
1.0
1.0
—
—
—
0
0
18
136
1.33
0.49
2.4
2.2
133.30
130.97
g/l
—
10
109
202
1894
1.09
0.49
4.5
4.1
7.87
9.17
mg/mmol
0.24
128
1196
24
190
1.27
0.48
1.2
1.2
—
—
—
0
0
59
672
0.87
0.46
1.4
1.3
—
—
—
0
0
13
94
1.39
0.46
1.8
3.5
—
—
—
0
0
7
50
1.40
0.45
1.0
1.1
—
—
—
0
0
7
51
1.38
0.44
1.4
1.7
—
—
—
0
0
22
273
0.80
0.43
1.3
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
17.84
—
0
8
0
15
0.00
0.41
0.0
1.1
—
0.65
—
0
10
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
22
271
0.81
0.41
1.3
2.0
—
—
—
0
0
80
722
1.12
0.41
1.7
1.6
—
—
—
0
0
21
260
0.80
0.41
1.2
2.0
—
—
—
0
0
17
132
1.30
0.40
1.9
1.7
164.40
131.20
au/ml
—
5
42
542
5319
1.09
0.40
6.9
6.3
39.19
39.17
mmol/mol
0.01
501
5018
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
162
1724
0.92
0.39
1.5
1.5
—
—
—
0
0
96
1045
0.91
0.38
2.9
3.1
0.70
0.74
ug/l
0.19
67
664
9
68
1.33
0.37
2.3
2.1
—
—
—
0
0
35
300
1.18
0.37
1.9
1.5
0.37
0.30
mg/l
0.27
18
133
5
76
0.66
0.36
1.0
1.1
—
—
—
0
0
39
447
0.86
0.35
4.1
3.6
1.22
1.23
mmol/l
0.44
34
389
18
222
0.81
0.35
1.6
1.6
57.12
8.44
u/ml
—
5
38
54
603
0.89
0.34
1.9
1.5
—
—
—
0
0
34
293
1.17
0.34
5.0
3.5
1.02
1.02
ratio
0.35
27
277
215
2054
1.07
0.33
3.8
3.6
7.15
7.77
mmol/l
1.29
184
1766
118
1105
1.08
0.31
1.8
1.9
—
—
—
0
0
62
564
1.11
0.30
1.2
1.2
—
—
—
0
0
12
152
0.79
0.29
1.3
1.0
—
—
—
0
0
68
740
0.91
0.28
1.4
1.3
—
—
—
0
0
10
76
1.32
0.28
1.5
2.8
—
—
—
0
0
15
122
1.23
0.27
3.9
2.8
—
—
—
0
0
11
139
0.79
0.27
1.0
1.1
0.30
2.20
u/ml
—
5
88
17
142
1.20
0.25
7.2
4.5
—
—
—
0
0
10
126
0.79
0.24
1.0
1.1
—
—
—
0
0
10
126
0.79
0.24
1.0
1.1
—
—
—
0
0
6
82
0.73
0.24
1.8
1.9
—
—
—
0
0
156
1492
1.06
0.24
3.4
2.9
325.14
342.67
umol/l
1.41
137
1327
17
143
1.19
0.23
2.0
1.7
—
—
—
0
0
13
106
1.23
0.23
1.1
1.0
—
—
—
0
0
24
273
0.87
0.22
1.3
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
1.75
—
0
11
0
11
0.00
0.21
0.0
5.0
—
8.80
—
0
11
0
11
0.00
0.21
0.0
1.1
—
29.98
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
4.48
—
0
10
0
10
0.00
0.21
0.0
1.6
—
0.49
—
0
10
0
12
0.00
0.21
0.0
2.1
—
2.75
—
0
12
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
24
271
0.88
0.20
1.3
2.0
—
—
—
0
0
31
344
0.90
0.20
1.1
1.2
—
122.00
—
0
13
29
322
0.90
0.19
1.0
1.1
—
—
—
0
0
54
580
0.93
0.19
1.5
1.8
—
—
—
0
0
12
143
0.84
0.18
1.6
1.4
—
—
—
0
0
5
68
0.73
0.17
1.4
1.2
—
—
—
0
0
160
1550
1.04
0.16
1.4
1.4
0.83
2.17
u/ml
1.90
32
400
123
1186
1.05
0.15
1.9
1.7
447.48
16683760.14
pmol/l
0.72
103
1001
39
418
0.93
0.14
3.3
3.5
334.21
217.43
ng/l
0.43
39
380
250
2451
1.03
0.13
1.9
1.9
1.39
1.35
mmol/l
0.21
216
2098
14
159
0.88
0.13
5.6
3.0
1.46
1.56
mmol/l
0.36
14
154
77
804
0.95
0.13
1.3
1.3
—
—
—
0
0
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
6
56
1.07
0.08
1.0
1.2
—
—
—
0
0
13
144
0.90
0.08
5.0
2.8
55.02
56.44
%
0.11
13
144
6
58
1.03
0.08
4.2
4.7
—
53.06
—
0
21
56
580
0.96
0.07
3.7
4.6
169.66
30.38
ug/l
0.40
44
484
561
5635
0.97
0.07
6.0
5.7
2.67
2.70
mmol/l
0.32
522
5275
526
5287
0.98
0.07
4.6
4.2
1.38
1.29
mmol/l
2.54
484
4900
26
245
1.06
0.07
1.5
1.5
—
—
—
0
0
7
81
0.86
0.07
1.3
1.2
—
—
—
0
0
21
196
1.07
0.07
2.2
2.6
—
—
—
0
0
24
255
0.94
0.07
2.0
1.3
—
—
—
0
0
554
5563
0.98
0.06
5.4
5.1
4.55
4.62
mmol/l
0.73
513
5222
109
1112
0.98
0.06
1.2
1.3
43.57
31.85
iu/ml
0.21
19
352
15
161
0.93
0.05
1.0
1.2
0.28
2.95
u/ml
—
5
101
10
110
0.91
0.05
1.5
1.5
—
—
—
0
0
10
93
1.08
0.02
5.7
3.0
3.43
4.27
e9/l
—
10
93
15
143
1.05
0.01
1.0
1.1
0.43
1.40
u/ml
—
5
87
14
134
1.05
0.00
1.4
2.4
—
—
—
0
0
138
1374
1.01
0.00
8.2
5.0
—
—
—
0
0
15
145
1.04
0.00
1.0
1.1
8.02
7.76
u/ml
—
8
96
10
103
0.97
0.00
1.3
1.2
—
—
—
0
0
12
119
1.01
0.00
3.7
2.7
11.28
8.41
pmol/l
0.46
12
119
14
139
1.01
0.00
1.8
2.5
63.00
67.98
ug/min
—
8
80
80
799
1.00
0.00
2.7
2.7
171.42
109.28
ug/g
0.60
67
641
0
8
0.00
0.00
0.0
1.0
—
0.02
—
0
8
0
5
0.00
0.00
0.0
1.0
—
34.26
—
0
5
6
67
0.89
0.00
1.8
2.1
35.17
32.81
pg
—
6
67
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
21
210
1.00
-0.00
1.9
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
40.33
—
0
9
6
69
0.87
-0.00
1.5
2.3
—
—
—
0
0
7
73
0.96
-0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
178.33
—
0
6
5
58
0.86
-0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
17.28
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
71
0.99
-0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: H7_OPTIC_ATROPHY – Optic atrophy

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).