Optic atrophy, wide definition

H7_OPTATROPHY_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H47.2, H48.0*, H48.0*A52.1
  • Hospital discharge: ICD-9 3771
  • Hospital discharge: ICD-8 37790
  • Cause of death: ICD-10 H47.2, H48.0*, H48.0*A52.1
  • Cause of death: ICD-9 3771
  • Cause of death: ICD-8 37790

2 out of 7 registries used, show all original rules.

760

4. Check minimum number of events

None

760

5. Include endpoints

None

760

6. Filter based on genotype QC (FinnGen only)

686

Control definitions (FinnGen only)

Control exclude
H7_OPTNERVE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 686 376 310
Unadjusted period prevalence (%) 0.14 0.13 0.14
Median age at first event (years) 54.10 52.88 55.58

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
715
Matched controls
7150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H47.2
ICD-10 Finland
Optic atrophy
+∞
307.7
681
*
XCK00
NOMESCO Finland
Perimetry
20.8
291.8
255
186
H53.4
ICD-10 Finland
Visual field defects
25.2
178.4
131
63
CS494
NOMESCO Finland
Other visual field testing
19.8
144.0
117
70
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
18.2
139.0
118
77
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
8.3
132.3
211
343
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
42.4
125.0
76
20
G35
ICD-10 Finland
Multiple sclerosis
40.5
118.7
73
20
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
33.6
108.0
70
23
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
41.2
104.7
64
17
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
11.4
92.7
103
104
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
7.9
91.8
141
215
109
Kela drug reimbursment
Multiple sclerosis
52.0
91.6
53
11
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
26.5
89.8
63
26
H46
ICD-10 Finland
Optic neuritis
+∞
87.3
82
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.6
82.1
273
840
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
5.6
77.3
174
386
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.6
75.5
172
385
XCD10
NOMESCO Finland
Electrophysiological examination of eye
13.4
74.7
73
60
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
+∞
70.0
66
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.8
66.1
113
191
H47.1
ICD-10 Finland
Papilloedema, unspecified
639.8
60.7
59
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
21.8
59.7
45
22
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
20.8
58.5
45
23
XCK10
NOMESCO Finland
Photography of fundus of eye
4.9
56.3
144
351
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.7
56.0
153
393
Z3229
NOMESCO Finland
Other healthcare associate professional
4.7
51.7
136
338
N03AX14
ATC
levetiracetam; systemic
8.7
51.6
68
85
TAB00
NOMESCO Finland
Lumbar puncture
6.3
50.2
91
162
AA1AD
NOMESCO Finland
CT of head and brain
3.2
49.8
306
1346
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
9.7
49.6
60
67
H02AB09
ATC
hydrocortisone; systemic
8.8
48.1
63
78
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
18.0
43.9
36
21
N86
ICPC
Multiple sclerosis
71.7
41.6
47
7
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
8.7
40.7
53
65
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
15.1
40.2
36
25
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
8.9
39.9
51
61
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
54.5
39.0
46
9
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
10.2
39.0
45
47
E23.00
ICD-10 Finland
Panhypopituitarism
86.9
37.2
41
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.0
33.3
104
290
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
8.1
32.6
45
59
37790
ICD-8 Finland
Other diseases of retina and optic nerve, Atrophia (et degeneratio) nervi optici (tabica excepta)
+∞
32.5
31
*
H47.3
ICD-10 Finland
Other disorders of optic disc
+∞
31.5
30
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.9
31.3
44
59
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.6
30.8
61
117
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
32.5
30.7
40
13
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
37.8
28.6
36
10
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.4
28.4
77
193
183
Kela drug reimbursment
Lamotrigin and topiramate
11.2
27.0
29
27
XA800
NOMESCO Finland
Neuropsychological investigation
4.4
26.0
70
174
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
22.9
25.9
37
17
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
34.5
25.8
33
10
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.9
23.9
132
522
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
31.2
22.9
30
10
N03AG01
ATC
valproic acid; systemic, rectal
3.7
22.7
78
231
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
18.7
22.4
34
19
N03AF02
ATC
oxcarbazepine; oral
4.8
22.3
52
115
G91.0
ICD-10 Finland
Communicating hydrocephalus
27.4
21.5
29
11
H53.2
ICD-10 Finland
Diplopia
5.2
21.4
45
91
M03BX01
ATC
baclofen; systemic
6.6
20.7
34
54
102
Kela drug reimbursment
Diabetes insipidus
216.0
20.7
21
*
H54.7
ICD-10 Finland
Unspecified visual loss
23.2
20.5
29
13
SPAT1229
SPAT
Assessment of need for aid
3.4
20.5
78
247
G91.1
ICD-10 Finland
Obstructive hydrocephalus
28.0
20.2
27
10
L03AB07
ATC
interferon beta-1a; parenteral
59.3
20.0
23
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
41.4
19.6
24
6
WX882
NOMESCO Finland
High dependency care
4.3
19.0
51
126
3771A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic atrophy
+∞
18.8
18
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
+∞
18.8
18
*
3400A
ICD-9 Finland
Multiple sclerosis[SCLEROSIS MULTIPLEX (DISSEMINATA)]
+∞
18.8
18
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
18.5
142
656
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
18.5
159
773
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
5.7
18.1
34
62
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
33.9
18.1
23
7
N04BB01
ATC
amantadine; oral
13.6
17.6
30
23
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.1
16.6
29
49
H54.0
ICD-10 Finland
Blindness, binocular
173.9
16.6
17
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
16.5
151
751
N05BA09
ATC
clobazam; oral
14.7
16.4
27
19
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
41.1
16.4
20
5
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.7
16.3
26
40
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
30.8
16.2
21
7
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
48.7
16.1
19
*
L03AX13
ATC
glatiramer acetate; parenteral
48.7
16.1
19
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
15.9
93
375
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
16.1
15.8
25
16
H54.4
ICD-10 Finland
Blindness, monocular
27.0
15.7
21
8
N03AX18
ATC
lacosamide; systemic
14.2
15.6
26
19
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.6
15.0
50
145
N05CD08
ATC
midazolam; nasal, systemic
4.6
14.6
35
79
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
81.8
14.6
16
*
N03AF01
ATC
carbamazepine; oral, rectal
3.4
14.4
54
169
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
22.8
14.3
20
9
R35
ICD-10 Finland
Polyuria
2.9
14.1
68
247
A06AD11
ATC
lactulose; oral
2.3
14.0
124
605
Z2445
NOMESCO Finland
Psychologist
3.3
13.9
54
173
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
20.5
13.8
20
10
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.7
13.7
45
129
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.7
13.6
79
317
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
142.6
13.5
14
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
5.2
13.5
28
56
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.7
13.4
78
313
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
13.0
310
2130
G93.2
ICD-10 Finland
Benign intracranial hypertension
51.0
12.9
15
*
N03AE01
ATC
clonazepam; systemic
3.2
12.8
52
171
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.3
12.8
26
51
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
20.5
12.5
18
9
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
20.5
12.5
18
9
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
4.8
12.4
28
60
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.0
12.4
56
196
N03AX16
ATC
[U] pregabalin
2.0
12.4
174
1008
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
12.3
119
600
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.9
12.2
60
220
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
12.2
119
603
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.4
12.0
43
131
N03AX11
ATC
topiramate; oral
4.3
11.9
31
75
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
11.7
131
698
L04AA27
ATC
[U] fingolimod
66.1
11.6
13
*
34099
ICD-8 Finland
Multiple sclerosis
121.9
11.5
12
*
SPAT1216
SPAT
Assessment of functional ability
2.1
11.4
121
632
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
13.0
11.2
19
15
H34.1
ICD-10 Finland
Central retinal artery occlusion
20.4
11.2
16
8
H01AC01
ATC
somatropin; parenteral
8.8
11.1
23
27
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.8
11.1
20
35
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
14.2
11.0
18
13
N05BA01
ATC
diazepam; systemic, rectal
2.1
10.9
107
541
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
44.0
10.9
13
*
164
Kela drug reimbursment
Fingolimod
44.0
10.9
13
*
N03AB02
ATC
phenytoin; systemic
5.5
10.9
21
39
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
12.2
10.9
19
16
Z2446
NOMESCO Finland
Social worker
2.5
10.8
70
296
L28
ICPC
Limited function/disability (L)
1.9
10.8
146
832
ZXA10
NOMESCO Finland
Bilateral
1.9
10.7
144
819
ZXC95
NOMESCO Finland
Use of surgical navigator
8.2
10.7
23
29
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
8.2
10.7
23
29
E23.05
ICD-10 Finland
Lack of TSH
60.9
10.6
12
*
D35.30
ICD-10 Finland
Craniopharyngoma
60.9
10.6
12
*
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
10.6
62
249
-, ,
ICD-10 Finland
4.3
10.6
27
64
Z3231
NOMESCO Finland
Registered nurse
1.8
10.6
214
1381
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
8.7
10.6
22
26
F02.89*G35
ICD-10 Finland
Dementia in multiple sclerosis
111.6
10.4
11
*
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
10.4
10
*
36703
ICD-8 Finland
Inflammation of optic nerve and retina, Neuritis optica, retrobulbaris
+∞
10.4
10
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.3
10.4
40
127
114
Kela drug reimbursment
Glaucoma
2.4
10.4
72
314
L03AB08
ATC
interferon beta-1b; parenteral
33.0
10.4
13
*
N03AX09
ATC
lamotrigine; oral
2.9
10.3
48
171
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
23.8
10.3
14
6
P85
ICPC
Mental retardation
13.4
10.2
17
13
XKD00
NOMESCO Finland
Uroflowmetry
2.1
10.1
109
572
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
10.1
72
319
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
40.7
10.0
12
*
ZXD05
NOMESCO Finland
Urgent procedure
1.7
9.9
219
1446
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
20.4
9.8
14
7
G04BD07
ATC
tolterodine; oral
3.0
9.8
44
154
353
Kela drug reimbursment
Cladribine and fingolimod
55.8
9.7
11
*
OAB43, ,
SPAT
0.5
9.6
75
1456
G04BD09
ATC
trospium; oral
4.3
9.4
24
57
E22.80
ICD-10 Finland
Central precocious puberty
101.3
9.4
10
*
ZXC86
NOMESCO Finland
Use of endoscopic device
17.8
9.4
14
8
H48.1*G35
ICD-10 Finland
Retrobulbar neuritis in multiple sclerosis
+∞
9.4
9
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
10.9
9.3
17
16
XKC03
NOMESCO Finland
Water cystometry
3.6
9.3
31
90
H26.4
ICD-10 Finland
After-cataract
2.2
9.2
79
379
R4120
NOMESCO Finland
Occupational therapy
2.4
9.2
63
274
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.7
9.1
28
77
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.2
9.0
24
59
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
37.2
9.0
11
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.6
8.9
52
209
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
12.7
8.9
15
12
SPAT1172
SPAT
Guidance concerning hydration
4.6
8.9
21
47
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.4
8.9
32
98
L04AX01
ATC
azathioprine; systemic
3.0
8.8
38
130
SPAT1234
SPAT
Support of social functional capacity
2.8
8.8
43
158
H40.11
ICD-10 Finland
Low pressure glaucoma
4.3
8.7
22
52
2132
FHL
Ventricular operators sunt
50.6
8.7
10
*
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
50.6
8.7
10
*
G81.1
ICD-10 Finland
Spastic hemiplegia
50.6
8.7
10
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
7.8
8.7
19
25
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
8.7
334
2526
H54.5
ICD-10 Finland
Severe visual impairment, monocular
11.8
8.6
15
13
AA1AA
NOMESCO Finland
Head X-ray examination
7.1
8.6
20
29
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
8.6
68
315
G91.8
ICD-10 Finland
Other hydrocephalus
27.9
8.5
11
*
E23.2
ICD-10 Finland
Diabetes insipidus
91.1
8.4
9
*
L04AA31
ATC
[U] teriflunomide
91.1
8.4
9
*
S01ED01
ATC
timolol; ophthalmic
3.4
8.4
30
91
R51.80
ICD-10 Finland
Headache
1.9
8.4
125
730
301
Kela drug reimbursment
Growth hormone
13.0
8.4
14
11
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
8.4
233
1625
A28
ICPC
Limited function/disability NOS
1.8
8.3
133
795
N18
ICPC
Paralysis/weakness
4.2
8.3
22
54
SPAT1254
SPAT
Administration of medicine
1.9
8.3
110
620
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
8.3
266
1922
F83
ICD-10 Finland
Mixed specific developmental disorders
6.6
8.2
20
31
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
14.7
8.2
13
9
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
8.1
53
225
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
33.8
8.1
10
*
CS2P4
NOMESCO Finland
Optic nerve head imaging
9.1
8.1
16
18
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
9.1
8.1
16
18
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
9.1
8.1
16
18
A02BC03
ATC
lansoprazole; oral
1.7
8.1
195
1310
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.0
8.0
36
126
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
7.9
98
538
S01EE04
ATC
travoprost; ophthalmic
4.5
7.9
19
43
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
7.9
7.9
17
22
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
13.2
7.9
13
10
H53.0
ICD-10 Finland
Amblyopia ex anopsia
6.2
7.9
20
33
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
7.9
93
503
PAW37
NOMESCO Finland
Biopsy of temporal artery
11.0
7.8
14
13
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
7.1
7.8
18
26
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
7.8
199
1354
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
7.8
246
1765
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
15.2
7.7
12
8
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.0
7.7
20
34
H03AA01
ATC
levothyroxine sodium; systemic
1.7
7.7
162
1047
G40.89
ICD-10 Finland
Other epilepsy
12.0
7.6
13
11
R32
ICD-10 Finland
Unspecified urinary incontinence
3.5
7.6
26
77
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
25.3
7.6
10
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
7.6
257
1871
PA2AD
NOMESCO Finland
CT angiography of brain
9.0
7.6
15
17
ZXA00
NOMESCO Finland
Right side
1.7
7.6
184
1235
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
10.2
7.6
14
14
H25.8
ICD-10 Finland
Other senile cataract
2.1
7.5
77
395
UKC02
NOMESCO Finland
Cystoscopy
1.9
7.5
109
632
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
80.9
7.4
8
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
80.9
7.4
8
*
N99
ICPC
Neurological disease other
6.1
7.4
19
32
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
6.1
7.4
19
32
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
8.5
7.3
15
18
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
6.9
7.3
17
25
37799
ICD-8 Finland
Other diseases of retina and optic nerve, Unspecified
+∞
7.3
7
*
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
+∞
7.3
7
*
74200
ICD-8 Finland
Congenital hydrocephalus, Communicans
+∞
7.3
7
*
C72.3
ICD-10 Finland
Malignant neoplasm: Optic nerve
+∞
7.3
7
*
N28
ICPC
Limited function/disability (N)
4.4
7.2
18
42
R3120
NOMESCO Finland
Training in mobility skills
15.9
7.2
11
7
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
7.2
93
518
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
30.3
7.2
9
*
Z02.7
ICD-10 Finland
Issue of medical certificate
2.2
7.1
60
285
G93.0
ICD-10 Finland
Cerebral cysts
20.3
7.1
10
5
L04AX07
ATC
dimethyl fumarate; oral
20.3
7.1
10
5
N29
ICPC
Neurological sympt/complt other
4.1
7.1
19
47
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
4.1
7.1
19
47
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.1
7.1
19
47
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.1
7.1
19
47
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
7.1
116
697
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.0
7.0
30
102
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
7.0
190
1309
L04AA06
ATC
mycophenolic acid; systemic
3.8
7.0
21
57
R42
ICD-10 Finland
Dizziness and giddiness
1.7
7.0
159
1048
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.3
6.9
53
242
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
6.9
101
585
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
7.6
6.9
15
20
XCH05
NOMESCO Finland
Eye pressure longterm registration
7.6
6.9
15
20
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
7.6
6.9
15
20
RD210, ,
NOMESCO Finland
3.6
6.9
22
62
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
6.8
93
527
RS222, ,
NOMESCO Finland
6.8
6.8
16
24
G41.9
ICD-10 Finland
Status epilepticus, unspecified
11.1
6.8
12
11
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.6
6.8
40
162
G40
ICD-10 Finland
Epilepsy
5.7
6.8
18
32
R62.0
ICD-10 Finland
Delayed milestone
5.7
6.8
18
32
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
40.4
6.8
8
*
RS140, ,
NOMESCO Finland
16.9
6.8
10
6
H52.0
ICD-10 Finland
Hypermetropia
3.3
6.8
25
78
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.6
6.6
38
152
S00.0
ICD-10 Finland
Superficial injury of scalp
3.3
6.6
24
74
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
12.4
6.6
11
9
H50.31
ICD-10 Finland
Intermittent exotropia
4.2
6.6
17
41
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.1
6.5
65
330
N06AX21
ATC
duloxetine; oral
1.9
6.5
84
468
S01ED51
ATC
timolol, combinations; ophthalmic
2.1
6.5
58
283
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.5
6.5
22
65
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
70.5
6.4
7
*
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
70.5
6.4
7
*
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
70.5
6.4
7
*
G40.10
ICD-10 Finland
Simple partial seizures
7.5
6.4
14
19
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
14.5
6.4
10
7
SPAT1255
SPAT
Intravenous administration of medicine
2.3
6.4
46
205
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.2
6.4
18
35
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
3.6
6.4
20
56
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.0
6.3
27
92
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.4
6.3
22
66
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
6.3
80
443
WF099
NOMESCO Finland
Other radiotherapy
9.4
6.3
12
13
H52.1
ICD-10 Finland
Myopia
2.7
6.3
34
132
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
6.3
254
1906
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
18.2
6.3
9
5
2377A
ICD-9 Finland
Neoplasm of uncertain behaviour of endocrine glands and nervous system, Neurofibromatosis
+∞
6.3
6
*
3773B
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic neuritis[NEURITIS RETROBULBARIS]
+∞
6.3
6
*
AAK00
NOMESCO Finland
Cranioplasty
+∞
6.3
6
*
E23.0
ICD-10 Finland
Hypopituitarism
+∞
6.3
6
*
7423A
ICD-9 Finland
Other congenital anomalies of nervous system, Congenital hydrocephalus
+∞
6.3
6
*
N07XX09
ATC
[U] dimethyl fumarate
26.9
6.2
8
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
6.2
207
1489
N88
ICPC
Epilepsy
8.7
6.1
12
14
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.1
247
1854
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
10.1
6.0
11
11
N03AX12
ATC
[U] gabapentin; oral
1.7
6.0
113
705
H53.8
ICD-10 Finland
Other visual disturbances
3.9
6.0
17
44
N06AX16
ATC
venlafaxine; oral
1.8
6.0
99
595

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
72
130
6.05
38.91
2.0
1.9
—
—
—
0
0
78
160
5.35
36.74
1.6
1.9
611.89
446.19
mg/l
0.71
72
151
48
62
8.23
35.26
1.8
2.0
—
—
—
0
0
69
142
5.27
32.30
1.5
1.8
3.73
3.66
mmol/l
0.15
64
134
66
139
5.13
30.07
1.9
1.8
21.83
16.64
e6/l
0.12
52
107
66
141
5.06
29.57
2.0
1.9
1226.19
924.21
e6/l
0.11
52
112
45
72
6.60
27.28
2.1
2.4
—
—
—
0
0
38
60
6.63
23.30
3.5
1.5
1038.21
270.11
mu/l
0.61
33
47
30
44
7.07
19.66
1.2
1.0
246.28
202.14
mg/l
0.87
25
37
40
83
5.05
18.46
1.2
1.2
—
—
—
0
0
26
35
7.67
18.34
1.3
1.1
0.86
0.50
ratio
2.04
16
17
143
682
2.37
17.25
3.9
2.0
369.92
367.50
nmol/l
0.02
133
638
406
2889
1.94
16.44
11.6
7.7
1.21
1.21
mmol/l
1.17
380
2685
42
101
4.36
16.23
4.7
6.2
431.20
367.98
umol/l
1.30
35
94
293
1902
1.92
15.36
2.7
2.2
193.34
237.01
u/l
0.46
274
1813
434
3202
1.90
15.26
10.9
8.1
1.21
1.21
mmol/l
0.03
390
2811
239
1502
1.89
13.46
2.9
2.4
—
—
—
0
0
172
974
2.01
13.14
2.3
2.3
29.05
29.42
s
0.43
166
945
471
3670
1.83
12.83
8.1
5.9
6.66
6.65
mmol/l
0.02
457
3482
39
106
3.83
12.81
2.2
1.5
24.25
25.31
ng/l
0.07
39
106
60
222
2.86
12.04
2.7
1.6
6.57
8.91
u/l
0.75
43
172
108
534
2.20
11.71
4.4
2.7
9.84
10.56
g/l
1.03
99
494
272
1846
1.76
11.53
4.5
3.1
—
—
—
0
0
140
771
2.01
11.43
1.9
1.7
—
—
—
0
0
496
4011
1.77
10.99
7.6
4.6
3696.75
2646.48
e6/l
—
8
63
364
2720
1.69
10.62
6.8
5.5
35.24
35.88
g/l
1.25
338
2562
420
3269
1.69
10.42
8.0
7.0
10.78
12.77
umol/l
2.58
393
3112
157
927
1.89
10.37
7.0
6.4
1.02
1.08
mmol/l
1.71
148
867
23
31
7.63
10.25
1.3
1.1
145.09
142.14
nmol/l
0.08
23
31
119
648
2.00
9.95
13.3
11.0
—
—
—
0
0
150
2343
0.54
9.86
3.2
3.1
—
—
—
0
0
551
4654
1.80
9.84
10.3
8.3
86.62
81.95
u/l
0.98
513
4416
246
1682
1.71
9.82
7.0
4.4
—
—
—
0
0
131
751
1.91
9.40
9.9
10.1
7.42
7.41
ph
0.27
73
428
20
25
8.20
9.39
1.1
1.0
1810.75
1528.48
miu/ml
0.41
20
25
103
548
2.03
9.16
4.7
4.3
7.31
7.34
ph
0.46
80
404
129
744
1.90
9.07
10.0
10.1
0.45
0.92
mmol/l
0.57
107
616
276
1979
1.64
9.01
3.2
2.5
—
—
—
0
0
85
424
2.14
8.96
2.7
2.5
10.00
19.95
au/ml
—
5
42
351
2677
1.61
8.88
6.0
3.5
6.54
6.22
ph
4.84
183
1526
20
28
7.32
8.78
4.9
3.5
0.19
0.56
e9/l
1.32
14
13
15
14
10.92
8.32
1.3
1.0
—
—
—
0
0
23
59
3.99
8.20
3.2
2.7
41.96
38.23
%
0.53
23
59
171
1110
1.71
8.03
4.9
4.1
0.83
0.82
mmol/l
0.64
165
1056
409
3283
1.57
7.99
11.1
6.6
0.61
0.58
e9/l
1.76
362
2799
409
3292
1.57
7.82
11.1
6.6
0.04
0.04
e9/l
0.88
361
2811
18
26
7.07
7.81
3.1
3.5
28.90
34.74
umol/l
0.70
12
18
292
2184
1.57
7.69
10.7
6.5
—
—
—
0
0
418
3394
1.56
7.59
11.6
7.0
0.19
0.20
e9/l
0.77
371
2953
343
2675
1.54
7.41
2.3
2.1
93.86
95.98
pmol/l
0.36
192
1426
412
3349
1.54
7.33
11.3
6.7
1.92
1.99
e9/l
0.54
369
2937
355
2800
1.53
7.22
3.2
2.6
78.22
76.57
nmol/l
0.46
318
2544
77
408
1.99
6.90
7.6
5.3
—
—
—
0
0
120
734
1.76
6.88
8.6
5.1
1.85
1.70
mmol/l
0.14
107
619
80
431
1.96
6.84
3.2
1.7
0.93
1.37
g/l
2.44
75
401
440
3659
1.53
6.82
14.2
9.9
4.40
4.05
e9/l
1.96
390
3166
378
3053
1.51
6.67
10.7
6.6
57.28
56.35
%
0.75
364
2925
86
487
1.87
6.34
2.9
2.8
66.57
67.01
g/l
0.23
80
456
166
1137
1.60
6.16
3.7
3.1
1.15
0.89
e6/l
0.50
92
590
120
758
1.70
6.11
8.7
5.1
7.37
7.38
ph
0.39
78
445
116
726
1.71
6.11
4.0
3.1
1.81
1.74
%
0.37
106
662
372
3033
1.47
6.03
11.4
6.8
8.99
8.79
%
0.66
357
2860
97
584
1.76
5.85
2.7
2.1
0.18
0.04
estimate
0.34
11
130
119
760
1.68
5.81
8.7
5.0
5.84
5.77
kpa
0.26
119
739
234
1751
1.50
5.78
1.9
1.7
19.05
19.99
nmol/l
0.45
199
1478
148
1001
1.60
5.76
1.8
1.7
1232.35
1201.03
nmol/l
0.15
113
778
85
497
1.81
5.66
2.4
2.4
4.08
7.60
ug/l
3.22
69
441
537
4743
1.53
5.62
5.6
4.3
14.95
14.75
pmol/l
1.02
495
4360
656
6095
1.92
5.58
29.1
18.9
139.58
139.65
mmol/l
0.28
642
5986
10
10
10.12
5.54
1.6
1.4
—
—
—
0
0
367
3021
1.44
5.44
11.5
6.8
0.68
0.68
%
0.09
352
2838
239
1814
1.48
5.44
7.1
4.0
0.00
0.01
estimate
0.96
52
631
656
6103
1.91
5.44
28.8
19.1
3.95
3.97
mmol/l
1.24
638
5977
106
668
1.69
5.43
8.0
4.6
5.20
4.59
kpa
2.15
106
648
397
3320
1.44
5.38
6.4
3.9
0.00
5.33
estimate
0.80
59
681
367
3030
1.43
5.31
11.4
6.7
2.83
2.97
%
0.56
352
2851
91
555
1.73
5.25
2.5
3.0
74.07
68.87
e9/l
0.72
60
416
488
4256
1.46
5.18
7.3
4.5
—
2.94
—
0
7
220
1657
1.47
5.16
2.7
2.4
3.10
2.87
mg/l
0.84
191
1427
373
3099
1.43
5.15
11.2
6.7
27.99
28.53
%
0.40
363
2952
193
1419
1.49
5.10
3.7
2.8
6.06
4.93
e6/l
0.63
181
1296
47
235
2.07
4.97
1.2
1.2
—
—
—
0
0
58
316
1.91
4.83
3.0
2.2
0.00
0.01
estimate
—
8
106
339
2795
1.40
4.75
15.2
13.9
1.25
1.24
inr
0.02
264
2320
264
2085
1.42
4.73
4.7
3.5
257.27
74.56
e6/l
0.40
206
1589
395
3348
1.40
4.69
6.5
3.9
0.00
0.49
estimate
0.52
59
638
389
3289
1.40
4.68
6.3
3.9
0.02
0.00
estimate
0.44
58
672
86
536
1.69
4.59
7.9
5.0
7.41
7.41
ph
0.06
75
436
131
906
1.55
4.57
2.5
2.2
—
—
—
0
0
83
516
1.69
4.47
1.8
1.4
—
—
—
0
0
99
645
1.62
4.45
2.6
2.6
0.20
0.21
g/l
0.58
93
611
198
1500
1.44
4.41
7.9
4.0
1.02
1.02
kg/l
0.08
137
1009
222
1719
1.42
4.38
4.1
3.3
—
0.00
estimate
—
0
10
80
499
1.68
4.26
5.3
4.5
81.07
79.56
ng/l
0.05
72
455
41
757
0.51
4.26
1.6
1.6
—
—
—
0
0
293
2389
1.38
4.25
5.6
4.2
106.51
98.28
e6/l
0.05
209
1664
231
1810
1.41
4.24
4.1
3.4
0.55
0.38
e6/l
0.33
174
1322
10
17
5.95
4.14
2.2
2.1
26.34
17.09
umol/l
—
10
17
91
592
1.62
4.12
3.5
2.5
33.22
121.40
u/l
0.55
73
495
63
373
1.76
4.05
3.0
3.6
4.28
4.63
pmol/l
1.26
57
336
12
28
4.34
3.83
1.3
1.1
—
—
—
0
0
240
1926
1.37
3.73
8.7
6.5
—
—
—
0
0
283
2337
1.35
3.65
4.3
3.8
51.79
77.39
ng/l
0.30
226
1643
335
2844
1.33
3.56
3.2
2.8
—
—
estimate
—
0
0
234
1888
1.36
3.48
6.4
4.0
7.40
7.40
ph
0.19
177
1355
85
568
1.56
3.45
4.5
2.4
12.81
13.01
nmol/l
0.08
78
513
639
6030
1.56
3.37
24.5
15.9
27.69
23.48
mg/l
2.01
555
4912
238
1935
1.34
3.34
2.7
2.7
53.31
63.07
u/l
1.34
217
1803
13
38
3.46
3.32
5.5
3.1
1.74
1.84
umol/l
0.14
13
32
13
43
3.06
3.26
2.5
3.0
387.54
971.98
mg
1.85
13
43
8
15
5.38
3.20
3.6
1.5
28.13
32.13
%
—
8
15
598
5589
1.43
3.10
6.1
5.3
1.95
1.91
mu/l
0.31
544
5187
44
255
1.77
3.09
1.7
2.0
1.64
1.46
g/l
0.56
38
232
18
74
2.47
3.07
7.8
4.2
—
—
—
0
0
32
566
0.55
2.92
1.3
1.4
—
—
—
0
0
159
1238
1.37
2.91
3.5
3.0
546.36
544.73
mosm/kgh2o
0.03
137
1087
133
1009
1.39
2.85
2.6
2.6
2.27
2.35
g/l
0.76
119
939
259
2173
1.30
2.82
3.3
3.6
2.37
2.36
mmol/l
0.37
227
1972
663
6348
1.61
2.82
29.5
20.3
74.70
76.01
umol/l
0.41
653
6280
8
18
4.48
2.80
2.4
1.7
—
—
—
0
0
139
1070
1.37
2.73
3.9
3.2
2.33
1.92
e6/l
0.25
62
525
26
478
0.53
2.70
1.4
1.8
3.46
3.48
mmol/l
0.03
19
349
124
939
1.39
2.69
2.7
2.7
20.64
22.31
%
0.62
113
886
10
30
3.37
2.61
3.1
1.9
179.60
120.93
ng/l
—
10
24
224
1860
1.30
2.61
3.5
3.4
1292.43
1300.47
ng/l
0.01
194
1585
7
15
4.70
2.60
3.9
2.2
1.19
1.14
umol/l
—
7
8
9
25
3.63
2.58
1.8
1.2
156.89
182.23
mmol/24h
—
9
25
12
42
2.89
2.55
4.0
1.8
17.81
19.38
umol/l
0.08
12
35
139
1081
1.35
2.55
2.7
2.7
11.89
13.12
umol/l
1.13
125
1012
273
2351
1.26
2.32
2.5
2.1
—
—
—
0
0
107
812
1.37
2.30
2.0
1.5
—
—
—
0
0
99
744
1.38
2.25
5.3
3.2
7.49
7.39
umol/l
0.03
90
660
9
30
3.03
2.15
3.9
3.2
371.89
679.73
u/ml
—
9
30
20
102
1.99
2.12
1.4
1.2
2.57
3.83
u/ml
—
7
47
655
6307
1.46
2.10
17.3
12.0
28.07
26.50
u/l
0.67
633
6148
8
25
3.22
2.10
1.5
1.4
—
—
—
0
0
0
55
0.00
2.07
0.0
3.9
—
15.81
—
0
41
7
20
3.52
2.06
1.1
1.5
722.43
68.25
nmol/24h
—
7
20
16
76
2.13
2.03
1.3
1.3
—
—
—
0
0
11
44
2.52
2.02
6.5
2.7
26.18
27.97
umol/l
0.31
11
39
116
915
1.32
1.94
1.4
1.3
476.52
474.63
titre
0.01
23
201
150
1227
1.28
1.92
3.3
2.9
2.47
2.45
mmol/l
0.77
130
1099
12
52
2.33
1.88
1.6
2.7
—
—
—
0
0
14
66
2.14
1.83
2.6
3.3
3.44
5.91
nmol/l
0.45
14
66
55
389
1.45
1.79
3.3
2.4
—
—
—
0
0
12
245
0.48
1.78
1.3
1.6
890.26
973.20
mu/l
0.17
12
203
29
178
1.66
1.75
1.4
1.2
—
—
—
0
0
244
2130
1.22
1.74
4.9
3.5
38.66
32.72
u/l
0.51
230
2026
9
36
2.52
1.74
44.4
39.9
7.37
7.17
ug/l
—
9
30
31
196
1.61
1.68
1.4
1.4
316.79
291.70
ug/g
0.22
15
120
17
90
1.91
1.66
1.1
1.2
—
—
—
0
0
8
31
2.60
1.66
2.4
2.5
112.87
82.79
ug/l
—
8
31
37
245
1.54
1.66
4.2
5.6
422.80
287.17
mg/l
0.21
15
131
280
2489
1.21
1.65
6.6
3.8
0.02
0.03
estimate
0.08
50
559
47
329
1.46
1.63
2.9
1.5
19.45
24.75
iu/l
0.54
37
268
485
5139
0.83
1.60
28.2
19.7
13.82
13.57
%
3.57
478
5097
320
2886
1.20
1.60
13.3
11.3
0.00
0.00
e9/l
0.31
261
2355
7
26
2.71
1.58
8.3
3.5
—
—
—
0
0
48
664
0.70
1.58
1.6
1.7
—
—
—
0
0
7
27
2.61
1.51
1.1
1.2
602.43
118.47
iu/ml
—
7
27
14
72
1.96
1.49
2.3
1.3
—
—
—
0
0
99
800
1.28
1.41
3.9
3.5
4.82
5.68
e9/l
0.49
82
702
5
17
2.95
1.36
1.8
2.5
—
—
—
0
0
38
269
1.44
1.28
2.5
1.8
—
—
—
0
0
590
5677
1.22
1.27
5.6
5.0
5.85
5.95
mmol/l
0.98
537
5253
26
171
1.54
1.25
3.6
3.5
1.14
2.45
index
1.25
14
103
62
480
1.32
1.23
3.3
2.3
6.10
6.10
ph
0.01
30
322
5
19
2.64
1.22
5.4
2.6
0.69
0.60
mmol/l
—
5
19
228
2039
1.17
1.20
3.8
3.6
—
0.71
—
0
7
19
117
1.64
1.19
3.6
3.1
2.41
2.38
mmol/l
0.02
11
78
56
430
1.33
1.19
1.3
1.3
120.65
163.51
u/ml
0.35
22
169
66
519
1.30
1.18
4.8
5.0
0.61
0.49
%
0.31
28
171
116
976
1.23
1.18
1.7
1.6
—
—
—
0
0
636
6180
1.26
1.17
20.7
14.0
—
—
—
0
0
13
72
1.82
1.15
1.0
1.2
—
—
—
0
0
65
516
1.29
1.10
5.5
5.2
0.18
0.13
%
0.26
28
154
13
218
0.59
1.09
1.0
1.1
1.47
1.53
g/l
0.41
13
218
207
1850
1.17
1.09
5.0
5.3
1.71
2.36
ug/l
1.60
184
1675
16
254
0.62
1.08
1.1
1.1
—
—
—
0
0
24
161
1.51
1.08
6.9
2.9
1.09
2.07
ratio
1.79
15
94
27
187
1.46
1.05
4.4
4.7
72.29
61.36
%
1.99
27
182
27
187
1.46
1.05
17.1
10.4
—
—
—
0
0
68
547
1.27
1.04
5.4
5.0
0.69
0.88
%
0.42
31
187
66
529
1.27
1.04
4.7
5.5
0.00
0.12
%
1.07
26
138
5
22
2.28
1.03
4.0
2.0
40.80
41.75
g/l
—
5
22
161
1419
1.17
1.01
2.0
1.9
1.33
1.31
mg/l
0.04
122
1101
55
433
1.29
1.00
7.1
4.5
129.64
128.63
g/l
0.14
55
424
435
4117
1.14
1.00
5.2
3.5
58.97
48.06
u/l
1.39
410
3902
60
479
1.28
0.99
1.4
1.6
—
—
—
0
0
319
2960
1.14
0.98
3.4
3.1
118.48
117.59
ug/l
0.03
289
2778
164
1451
1.17
0.98
2.1
1.5
2.00
2.37
g/l
2.14
106
861
40
302
1.34
0.98
7.5
4.4
25.24
25.04
mmol/l
0.10
40
292
18
116
1.57
0.97
1.7
1.9
—
—
—
0
0
17
108
1.59
0.97
1.4
1.9
—
—
—
0
0
17
108
1.59
0.97
1.4
1.9
—
—
—
0
0
17
108
1.59
0.97
1.4
1.9
—
—
—
0
0
17
108
1.59
0.97
1.4
1.9
—
—
—
0
0
10
54
1.86
0.97
3.4
2.2
—
—
—
0
0
9
50
1.81
0.97
1.3
1.1
105.33
104.26
pmol/l
—
9
50
22
149
1.49
0.96
3.5
1.8
—
—
—
0
0
669
6564
1.30
0.94
36.7
24.1
6.98
6.75
e9/l
2.16
652
6430
399
4208
0.88
0.91
4.3
4.1
—
0.27
—
0
11
13
79
1.66
0.88
6.4
6.9
13.55
10.95
%
1.90
13
79
38
290
1.33
0.88
1.2
2.0
0.86
7.36
iu/ml
—
5
74
8
44
1.83
0.86
5.6
2.5
19.13
37.24
mg/l
—
8
33
668
6562
1.27
0.85
36.7
24.1
257.23
251.34
e9/l
1.27
654
6443
668
6563
1.27
0.84
36.6
24.0
90.83
90.70
fl
0.26
658
6511
668
6564
1.27
0.83
37.7
24.8
39.88
40.38
%
1.63
658
6506
668
6564
1.27
0.83
36.6
24.0
30.15
30.24
pg
0.53
658
6511
668
6564
1.27
0.83
36.7
24.0
4.45
4.51
e12/l
2.52
652
6430
6
115
0.52
0.83
1.8
1.6
—
—
—
0
0
15
225
0.66
0.82
1.1
1.1
0.89
0.90
g/l
0.10
15
225
24
172
1.41
0.82
3.1
1.9
2.72
4.60
iu/l
—
6
61
19
130
1.47
0.81
3.5
2.9
—
—
—
0
0
668
6567
1.26
0.80
37.0
24.2
133.07
135.40
g/l
3.75
658
6512
15
223
0.67
0.80
1.3
2.0
—
—
—
0
0
28
208
1.36
0.78
2.4
2.2
10643.76
4712.91
u/l
—
7
84
133
1183
1.15
0.75
3.8
4.1
606.41
496.11
ng/l
0.11
99
907
9
53
1.71
0.75
1.0
1.2
—
—
—
0
0
11
67
1.65
0.75
1.6
1.7
91.08
90.29
%
0.14
11
67
5
24
2.09
0.74
7.8
3.4
—
—
—
0
0
22
299
0.73
0.73
2.1
1.7
—
—
—
0
0
163
1796
0.88
0.73
4.7
3.3
0.00
0.05
estimate
0.60
44
543
5
25
2.01
0.73
1.0
1.1
—
—
—
0
0
6
110
0.54
0.72
1.7
1.4
—
—
—
0
0
12
76
1.59
0.72
1.7
1.3
0.54
24.52
nmol/l
0.50
12
71
20
143
1.41
0.70
1.6
1.2
—
—
—
0
0
20
144
1.40
0.68
2.4
2.1
131.42
130.34
g/l
0.08
12
115
9
59
1.53
0.68
1.3
1.4
—
—
—
0
0
17
119
1.44
0.67
1.6
1.2
—
—
—
0
0
14
94
1.50
0.67
1.9
3.5
—
—
—
0
0
12
79
1.53
0.63
1.5
2.8
—
—
—
0
0
5
30
1.67
0.61
1.0
1.4
—
—
—
0
0
39
476
0.81
0.61
3.7
3.8
—
—
—
0
0
38
308
1.25
0.61
4.6
3.5
1.02
1.02
ratio
0.60
30
292
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
2.2
—
3803.70
—
0
10
0
21
0.00
0.60
0.0
2.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
12
80
1.51
0.60
1.0
1.3
—
98.12
—
0
6
96
1079
0.87
0.59
1.2
1.3
13.93
10.38
u/ml
0.14
31
414
0
23
0.00
0.58
0.0
2.0
—
886.53
—
0
17
7
114
0.61
0.58
1.0
1.1
—
—
—
0
0
8
54
1.49
0.57
4.5
4.0
0.13
0.76
index
—
8
54
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
6
36
1.67
0.56
1.0
1.8
—
—
—
0
0
167
1808
0.90
0.56
1.5
1.4
—
—
—
0
0
567
5790
0.90
0.52
5.3
5.0
1.41
1.45
mmol/l
1.61
523
5400
61
701
0.86
0.52
1.4
1.3
—
—
—
0
0
10
67
1.50
0.50
1.4
1.3
—
—
nmol/l
—
0
0
10
67
1.50
0.50
1.3
1.1
—
—
—
0
0
20
154
1.31
0.49
6.3
4.3
—
—
—
0
0
568
5562
1.10
0.48
6.8
6.3
39.20
39.23
mmol/mol
0.02
524
5243
208
1955
1.09
0.47
4.0
3.5
42.06
58.04
mg/l
0.81
135
1292
36
427
0.83
0.45
1.2
1.2
—
—
—
0
0
21
165
1.28
0.45
1.4
1.5
238.08
268.18
u/ml
0.22
13
76
22
275
0.79
0.45
1.3
1.9
—
—
—
0
0
84
755
1.13
0.45
1.7
1.6
—
—
—
0
0
7
51
1.38
0.44
1.0
1.1
—
—
—
0
0
38
322
1.19
0.43
1.4
1.2
—
—
—
0
0
22
273
0.80
0.43
1.3
1.9
—
—
—
0
0
5
31
1.62
0.43
4.4
2.4
—
—
—
0
0
8
56
1.43
0.42
1.3
1.4
—
—
—
0
0
8
57
1.41
0.42
1.0
1.2
—
—
—
0
0
8
57
1.41
0.42
3.1
2.5
—
—
—
0
0
21
261
0.80
0.42
1.2
2.0
—
—
—
0
0
35
296
1.19
0.41
2.2
2.5
—
—
—
0
0
211
1996
1.08
0.41
4.4
4.2
7.90
9.41
mg/mmol
0.30
135
1271
0
16
0.00
0.41
0.0
1.1
—
17.52
—
0
9
0
16
0.00
0.41
0.0
1.1
—
0.65
—
0
10
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.2
1.8
94.50
102.84
ng/l
—
5
35
102
1109
0.91
0.39
3.0
3.1
0.71
0.74
ug/l
0.15
72
697
24
197
1.23
0.38
1.2
1.2
—
—
—
0
0
56
628
0.88
0.37
1.9
1.5
—
—
—
0
0
9
71
1.27
0.36
2.3
2.1
—
—
—
0
0
70
772
0.90
0.35
1.4
1.3
—
—
—
0
0
6
44
1.37
0.34
1.0
1.0
—
—
—
0
0
19
232
0.81
0.34
1.5
1.6
57.12
9.52
u/ml
—
5
42
10
133
0.75
0.33
1.0
1.1
—
—
—
0
0
10
133
0.75
0.33
1.0
1.1
—
—
—
0
0
11
143
0.77
0.32
1.0
1.1
0.30
2.11
u/ml
—
5
92
12
153
0.78
0.31
1.3
1.0
—
—
—
0
0
224
2149
1.06
0.30
3.8
3.6
7.19
7.82
mmol/l
1.39
193
1845
32
366
0.87
0.29
1.1
1.2
—
122.00
—
0
13
7
56
1.25
0.29
1.4
1.7
—
—
—
0
0
55
606
0.90
0.29
1.5
1.7
—
—
—
0
0
35
308
1.14
0.28
1.9
1.6
0.37
0.30
mg/l
0.25
18
134
165
1571
1.07
0.28
3.3
2.9
326.21
343.31
umol/l
1.43
145
1396
5
72
0.69
0.26
1.4
1.2
—
—
—
0
0
122
1154
1.07
0.25
1.8
1.9
—
—
—
0
0
17
142
1.20
0.25
1.9
1.7
164.40
132.79
au/ml
—
5
45
12
148
0.81
0.24
1.6
1.4
—
—
—
0
0
6
83
0.72
0.24
1.8
1.9
—
—
—
0
0
40
443
0.90
0.24
3.2
3.5
326.70
221.41
ng/l
0.39
40
405
24
275
0.87
0.23
1.3
1.8
—
—
—
0
0
13
107
1.22
0.21
1.1
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
1.75
—
0
11
0
11
0.00
0.21
0.0
1.5
—
0.47
—
0
11
0
11
0.00
0.21
0.0
1.1
—
29.98
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
4.48
—
0
10
0
12
0.00
0.21
0.0
4.7
—
8.54
—
0
12
24
272
0.88
0.21
1.3
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
4.15
—
0
13
63
589
1.08
0.19
1.2
1.2
—
—
—
0
0
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
80
841
0.95
0.16
1.3
1.3
—
—
—
0
0
6
80
0.75
0.15
1.0
1.1
—
—
—
0
0
30
327
0.91
0.15
1.0
1.1
—
—
—
0
0
7
87
0.80
0.14
1.3
1.2
—
—
—
0
0
11
93
1.19
0.14
5.7
3.0
3.32
4.32
e9/l
1.40
11
93
260
2549
1.03
0.13
1.9
1.9
1.38
1.35
mmol/l
0.19
225
2182
15
169
0.89
0.12
6.2
3.0
1.45
1.56
mmol/l
0.38
15
164
113
1164
0.97
0.11
1.2
1.3
44.44
31.96
iu/ml
0.24
20
362
10
115
0.87
0.10
1.5
1.5
—
—
—
0
0
17
154
1.11
0.10
2.0
1.7
—
—
—
0
0
15
166
0.90
0.10
1.0
1.2
0.28
2.86
u/ml
—
5
105
5
45
1.11
0.10
1.0
1.0
—
—
—
0
0
58
604
0.96
0.09
4.0
4.6
162.39
29.72
ug/l
0.40
46
501
128
1251
1.03
0.08
1.9
1.7
452.25
15799875.63
pmol/l
0.72
105
1057
5
61
0.82
0.08
1.4
1.4
—
—
—
0
0
82
844
0.97
0.08
2.8
2.6
168.71
108.97
ug/g
0.59
69
678
6
71
0.84
0.07
1.5
2.5
—
—
—
0
0
6
71
0.84
0.07
1.8
2.1
35.17
32.66
pg
—
6
71
8
75
1.07
0.07
1.3
1.1
—
—
—
0
0
21
197
1.07
0.06
2.2
2.6
—
—
—
0
0
25
263
0.95
0.05
2.0
1.3
—
—
—
0
0
164
1618
1.02
0.05
1.4
1.4
0.81
2.08
u/ml
1.90
33
426
588
5898
0.98
0.04
6.0
5.7
2.67
2.70
mmol/l
0.28
546
5518
552
5535
0.99
0.03
4.5
4.3
1.39
1.29
mmol/l
2.57
507
5125
581
5822
0.99
0.02
5.3
5.1
4.55
4.61
mmol/l
0.71
536
5462
10
107
0.93
0.02
1.3
1.2
—
—
—
0
0
145
1440
1.01
0.01
8.6
4.9
—
—
—
0
0
46
467
0.98
0.01
4.1
3.7
1.21
1.23
mmol/l
0.89
41
407
22
214
1.03
0.00
1.9
2.6
—
—
—
0
0
14
135
1.04
0.00
1.4
2.4
—
—
—
0
0
15
145
1.04
0.00
2.1
2.5
145.22
97.06
ug/min
—
9
84
13
126
1.03
0.00
3.5
3.2
10.48
8.70
pmol/l
0.27
13
126
15
146
1.03
0.00
1.0
1.1
0.43
1.38
u/ml
—
5
90
14
143
0.98
0.00
5.3
2.8
54.66
56.61
%
0.17
14
143
26
258
1.01
0.00
1.5
1.5
—
—
—
0
0
13
131
0.99
0.00
3.5
3.0
90.23
89.61
%
0.21
13
126
15
149
1.01
0.00
1.0
1.1
8.02
7.53
u/ml
—
8
99
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
0.02
—
0
9
0
9
0.00
0.00
0.0
1.3
—
40.33
—
0
9
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
17.76
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
34.26
—
0
5
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
178.33
—
0
6
7
75
0.93
-0.00
1.6
1.5
—
—
—
0
0
6
60
1.00
-0.00
4.2
4.6
—
52.83
—
0
22

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: H7_OPTATROPHY_WIDE – Optic atrophy, wide definition

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).