Psoriasis (vulgaris), strict definition

PSORI_STRICT

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • L12_PSORI_VULG
9489

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • KELA reimbursements: KELA codes 319|377|134

1 out of 7 registries used, show all original rules.

1507

4. Check minimum number of events

None

1507

5. Include endpoints

None

1507

6. Filter based on genotype QC (FinnGen only)

1372

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS
Control conditions
not L12_PSORI_VULG

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4808 1617 3168
Only index persons 4482 1538 2944
Unadjusted period prevalence (%)
Whole population 0.07 0.05 0.09
Only index persons 0.09 0.06 0.11
Median age at first event (years)
Whole population 51.67 54.18 50.42
Only index persons 51.17 53.78 49.80

-FinnGen-

Key figures

All Female Male
Number of individuals 1372 572 800
Unadjusted period prevalence (%) 0.30 0.20 0.37
Median age at first event (years) 53.07 53.69 52.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1423
Matched controls
14230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E000003, ,
ATC
18.9
307.7
350
242
D07AC01
ATC
betamethasone; topical
21.1
307.7
1235
3373
L04AD01
ATC
ciclosporin; systemic
30.6
307.7
221
85
L04AC05
ATC
ustekinumab; parenteral
235.6
307.7
268
14
D05BB02
ATC
acitretin; oral
536.2
307.7
873
42
D05AX02
ATC
calcipotriol; topical
253.5
307.7
886
92
134
Kela drug reimbursment
General erythroderma
944.1
307.7
356
5
D07AD01
ATC
clobetasol; topical
22.7
307.7
965
1210
L04AA32
ATC
apremilast; oral
+∞
307.7
331
*
TQW80
NOMESCO Finland
Local dermatologic skincare
28.6
307.7
275
118
L04AB04
ATC
adalimumab; parenteral
37.2
307.7
357
127
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
1611.9
307.7
578
6
E0000UV, ,
ATC
44.2
307.7
1343
3916
E000001, ,
ATC
14.5
307.7
901
1518
L04AC18
ATC
risankizumab; parenteral
+∞
307.7
311
*
L40.9
ICD-10 Finland
Psoriasis, unspecified
177.0
307.7
338
25
S91
ICPC
Psoriasis
181.8
307.7
229
15
377
Kela drug reimbursment
Apremilast and dimethyl fumarate (psoriasis)
+∞
307.7
373
*
D05AX03
ATC
calcitriol; topical
472.0
307.7
429
13
D07XC01
ATC
betamethasone; topical
72.1
307.7
1148
779
L04AC10
ATC
secukinumab; parenteral
309.0
307.7
254
10
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
+∞
307.7
997
*
D05AX52
ATC
calcipotriol, combinations; topical
441.0
307.7
1214
185
L01BA01
ATC
methotrexate; systemic
28.8
307.7
300
131
E000002, ,
ATC
9.8
307.7
507
764
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
83.5
307.7
271
40
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
10.4
307.7
496
698
D07AC13
ATC
mometasone; topical
8.5
307.7
938
2628
L40
ICD-10 Finland
Psoriasis
112.8
307.7
422
53
L40.5
ICD-10 Finland
Arthropathic psoriasis
2135.5
307.7
535
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
8474.3
307.7
1381
55
L04AX03
ATC
methotrexate; systemic
108.3
307.7
1173
591
L04AC16
ATC
guselkumab; systemic
3090.6
285.1
266
*
D07AB02
ATC
hydrocortisone butyrate; topical
6.7
284.5
860
2643
D07AB08
ATC
desonide; topical
8.3
280.5
460
774
D02AE01
ATC
carbamide; topical
10.9
274.0
332
385
L04AC13
ATC
ixekizumab; parenteral
750.4
260.4
249
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
739.4
257.1
246
*
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
6.1
253.7
710
1997
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
9.6
237.4
315
408
L04AB01
ATC
etanercept; parenteral
26.6
228.8
161
68
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
15.0
207.9
193
147
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
14.3
204.0
195
156
L40.8
ICD-10 Finland
Other psoriasis
329.1
199.7
198
7
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.4
195.7
328
551
D02AX
ATC
Other emollients and protectives
14.0
184.6
178
144
XQ848
NOMESCO Finland
Dermatological photography
13.2
179.4
179
153
E000007, ,
ATC
9.0
175.2
236
307
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.6
168.2
313
581
L04AA01
ATC
[U] ciclosporin
24.2
152.3
110
49
E000006, ,
ATC
7.2
140.8
232
377
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
6.9
138.9
239
406
A07EC01
ATC
sulfasalazine; oral, rectal
6.1
136.5
272
534
L04AA13
ATC
[U] leflunomide
14.5
133.7
124
93
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.8
126.3
928
4720
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
33.4
122.7
79
25
D05AA
ATC
Tars
153.4
120.3
126
9
D09AB01
ATC
zinc bandage without supplements; topical
15.3
119.7
107
75
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
+∞
119.5
113
*
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
67.0
116.4
64
10
299, ,
Kela drug reimbursment
+∞
116.3
110
*
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
115.2
109
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.7
111.7
303
771
L40.4
ICD-10 Finland
Guttate psoriasis
301.8
110.7
111
*
L04AC21
ATC
bimekizumab; systemic
1050.3
101.5
98
*
L04AA11
ATC
[U] etanercept
45.6
96.2
57
13
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
89.5
85
*
D07AA02
ATC
hydrocortisone; topical
3.5
79.2
334
1144
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.4
69.9
306
1066
L88
ICPC
Rheumatoid/seropositive arthritis
6.5
69.3
118
195
D05AX05
ATC
tazarotene; topical
667.8
65.4
64
*
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
9.5
60.0
72
79
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
55.6
728
4347
D07XB01
ATC
flumetasone; topical
22.8
54.6
40
18
NH3EA
NOMESCO Finland
Feet X-ray examination with load
8.9
52.8
67
79
TQW99
NOMESCO Finland
Other minor procedure on skin
4.7
51.4
125
285
H02AB06
ATC
prednisolone; systemic
2.3
49.6
762
4791
L40.1
ICD-10 Finland
Generalized pustular psoriasis
+∞
47.1
45
*
M07.0
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
451.3
44.5
44
*
6960A
ICD-9 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
44.0
42
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
43.9
203
719
L04AB06
ATC
golimumab; parenteral
11.6
43.3
45
40
A46
ICD-10 Finland
Erysipelas
2.7
42.1
273
1160
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
7.1
41.8
64
94
L26
ICD-10 Finland
Exfoliative dermatitis
113.4
41.0
44
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.7
40.9
138
400
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.0
40.5
195
706
D05AC01
ATC
dithranol; topical
408.7
40.3
40
*
E000004, ,
ATC
6.5
40.0
66
105
D05AX
ATC
Other antipsoriatics for topical use
398.1
39.3
39
*
D07BC01
ATC
betamethasone and antiseptics; topical
2.8
38.6
225
903
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
7.3
37.9
56
79
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.6
36.7
90
206
ZY010
NOMESCO Finland
Hospital outpatient
3.6
35.4
126
378
A10BA02
ATC
metformin; oral
2.1
34.7
446
2527
T90
ICPC
Diabetes non-insulin dependent
2.2
34.7
394
2128
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.2
34.6
375
1987
D07AC14
ATC
methylprednisolone aceponate; topical
3.9
33.3
102
276
J01DB01
ATC
cefalexin; oral
2.6
33.0
1238
10259
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
+∞
32.4
31
*
ZX112
NOMESCO Finland
Subcutaneous
5.6
31.2
60
111
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
5.4
30.7
62
120
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
5.0
30.4
67
140
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
29.9
398
2264
XQ845
NOMESCO Finland
Dermatoscopy
5.9
29.9
54
94
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.7
29.8
177
712
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
29.6
412
2381
TNG10
NOMESCO Finland
Puncture of knee
8.5
29.2
38
46
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
7.4
28.9
42
58
XQ802
NOMESCO Finland
Epicutan test
3.9
28.7
88
238
J01FF01
ATC
clindamycin; systemic
2.0
28.2
433
2583
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
27.8
187
799
M25.5
ICD-10 Finland
Pain in joint
1.9
27.8
540
3479
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
27.8
482
2993
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.9
27.5
138
508
WZC30
NOMESCO Finland
Teaching
2.2
27.2
282
1453
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
27.0
337
1864
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
6.3
25.9
44
72
A10BJ06
ATC
semaglutide; parenteral
2.9
25.6
129
475
E66.8
ICD-10 Finland
Other obesity
3.0
25.6
119
419
SPAT1262
SPAT
Handing over of treatment supplies
2.2
25.0
259
1332
L04AB05
ATC
certolizumab pegol; parenteral
23.9
24.9
35
15
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
24.5
215
1032
N05BB01
ATC
hydroxyzine; systemic
3.0
24.4
111
386
D07CC01
ATC
betamethasone and antibiotics; topical
2.3
24.2
209
996
ZXC50
NOMESCO Finland
Cryotherapy
4.7
24.2
57
126
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
6.2
23.8
41
68
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.8
23.8
124
465
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
5.6
23.5
45
83
SPAT1263
SPAT
Sampling
1.8
22.8
569
3897
R06AE07
ATC
cetirizine; oral
1.7
22.2
632
4485
D07AC03
ATC
desoximetasone; topical
5.4
22.1
44
84
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
7.3
21.7
32
45
E66.00
ICD-10 Finland
Metabolic syndrome
2.8
21.6
117
448
D11AH04
ATC
alitretinoin; oral
44.1
21.4
26
6
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
8.0
21.3
29
37
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.4
20.7
156
700
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
20.6
330
1966
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
20.6
543
3750
RJ411, ,
NOMESCO Finland
16.1
20.6
33
21
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.2
20.3
179
858
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
20.1
169
794
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
+∞
19.8
19
*
S18
ICPC
Laceration/cut
1.7
19.5
657
4826
L20
ICPC
Joint symptom/complaint NOS
3.4
19.5
70
211
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.3
18.9
49
117
Z3231
NOMESCO Finland
Registered nurse
1.8
18.3
374
2389
J01DA01
ATC
[U] cefalexin
1.7
18.3
858
6811
M01AH05
ATC
etoricoxib; oral
1.7
18.3
934
7578
RJ421, ,
NOMESCO Finland
19.6
18.2
27
14
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
18.1
85
301
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
17.7
523
3686
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.1
17.7
183
932
WQ031, ,
NOMESCO Finland
+∞
17.7
17
*
69600
ICD-8 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
17.7
17
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
17.2
787
6167
D07AB01
ATC
clobetasone; topical
3.6
17.1
56
159
G47.3
ICD-10 Finland
Sleep apnoea
1.7
17.0
393
2593
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.9
16.8
229
1288
C08CA01
ATC
amlodipine; oral
1.7
16.7
488
3419
L04AF07
ATC
deucravacitinib; oral
+∞
16.7
16
*
L40.2
ICD-10 Finland
Acrodermatitis continua
+∞
16.7
16
*
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
16.6
173
883
S97
ICPC
Chronic ulcer skin
2.6
16.6
99
398
A02BC02
ATC
pantoprazole; systemic
1.6
16.5
938
7712
A10BH01
ATC
sitagliptin; oral
2.2
16.3
140
662
L04AA21
ATC
[U] efalizumab
+∞
15.7
15
*
WQ053, ,
NOMESCO Finland
+∞
15.7
15
*
3088, ,
Kela drug reimbursment
+∞
15.7
15
*
M13.9
ICD-10 Finland
Arthritis, unspecified
2.4
15.6
116
516
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
3.6
15.5
52
150
M04AA01
ATC
allopurinol; systemic
2.0
15.3
168
875
WZA10
NOMESCO Finland
Extensive medical or dental certificate
4.5
15.2
37
84
SPAT1312
SPAT
General health counselling
1.7
15.2
397
2693
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
4.1
15.1
42
106
A10BK01
ATC
dapagliflozin; oral
2.2
15.1
132
629
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
15.0
204
1143
L30.3
ICD-10 Finland
Infective dermatitis
3.0
15.0
65
220
XQ800
NOMESCO Finland
Prick test
2.3
14.9
116
526
WQ066, ,
NOMESCO Finland
57.3
14.8
17
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
14.8
142
703
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
14.5
186
1023
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
14.4
631
4822
J02AC01
ATC
fluconazole; systemic
1.6
14.4
479
3439
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
14.1
490
3550
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
5.5
14.0
27
50
H02AB07
ATC
prednisone; oral
2.0
14.0
173
938
RS340, ,
NOMESCO Finland
30.4
13.9
18
6
RJ420, ,
NOMESCO Finland
13.7
13.7
23
17
T82
ICPC
Obesity
2.6
13.6
79
313
R4180
NOMESCO Finland
Podiatric therapy
4.8
13.6
30
63
D05AD01
ATC
trioxysalen; topical
+∞
13.6
13
*
M07.1*L40.5
ICD-10 Finland
Arthritis mutilans
+∞
13.6
13
*
291
Kela drug reimbursment
Tofacitinib
18.4
13.4
20
11
SPAT1301
SPAT
No procedures
1.6
13.3
369
2528
SPAT1254
SPAT
Administration of medicine
1.9
13.3
171
940
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
13.2
155
826
C03CA01
ATC
furosemide; systemic
1.7
13.2
294
1905
N02AX02
ATC
tramadol; systemic, rectal
1.5
13.0
581
4433
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
12.9
111
525
SPAT1260
SPAT
Consultation of another employee
1.8
12.9
214
1275
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.9
12.9
60
212
NG1DA
NOMESCO Finland
X-ray of knees
4.2
12.8
34
83
160
Kela drug reimbursment
exenatide
3.6
12.8
41
115
S76
ICPC
Skin infection other
2.4
12.7
88
379
J01CF05
ATC
flucloxacillin; systemic
2.1
12.5
117
572
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.0
12.5
54
183
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
3.8
12.4
38
103
QXA70
NOMESCO Finland
Guidance related to rash and skin care
37.9
12.2
15
*
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.9
12.2
177
1011
SPAT1310
SPAT
Counselling related to known health issue
1.6
12.1
386
2724
J01MA12
ATC
levofloxacin; systemic
1.7
12.1
235
1464
S02CA02
ATC
flumetasone and antiinfectives; otic
2.5
12.1
78
326
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.7
12.0
63
237
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
5.1
12.0
25
50
N02BE01
ATC
paracetamol; systemic, rectal
1.8
11.9
1227
11115
J01CE08
ATC
benzathine benzylpenicillin; parenteral
5.4
11.8
23
43
L30.8
ICD-10 Finland
Other specified dermatitis
3.1
11.8
50
167
WW200
NOMESCO Finland
Immunization
3.0
11.8
52
178
D07XB05
ATC
dexamethasone; topical
3.4
11.7
41
122
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
4.5
11.7
28
63
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
11.5
358
2506
L04AA29
ATC
[U] tofacitinib
13.7
11.5
19
14
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.5
11.5
73
303
H02AB04
ATC
methylprednisolone; systemic
1.8
11.4
187
1109
A10BJ02
ATC
liraglutide; parenteral
2.9
11.4
52
182
205
Kela drug reimbursment
Chronic hypertension
1.6
11.3
276
1823
M10.9
ICD-10 Finland
Gout, unspecified
2.2
11.2
100
480
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.6
11.2
37
106
R06AE09
ATC
levocetirizine; oral
1.7
11.1
202
1233
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
11.1
258
1684
D06BB04
ATC
podophyllotoxin; topical
2.3
11.0
87
398
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
10.9
165
954
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
10.9
328
2278
A10AE04
ATC
insulin glargine; parenteral
1.9
10.7
140
772
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
10.6
393
2853
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
10.6
146
819
L04AC12
ATC
brodalumab; systemic
+∞
10.4
10
*
WQ054, ,
NOMESCO Finland
+∞
10.4
10
*
EBA00
NOMESCO Finland
Extraction of tooth
1.5
10.4
504
3862
D01AC02
ATC
miconazole; topical
2.1
10.4
104
523
L43.8
ICD-10 Finland
Other lichen planus
12.1
10.4
18
15
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
10.3
300
2063
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
10.3
952
8234
R06AX27
ATC
desloratadine; oral
1.5
10.3
396
2896
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.4
10.3
70
300
RF120, ,
NOMESCO Finland
4.9
10.3
22
45
EC1VA, ,
NOMESCO Finland
2.3
10.1
75
334
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.5
10.1
34
99
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
4.8
10.0
22
46
A10BK03
ATC
empagliflozin; oral
1.8
10.0
147
842
M54.5
ICD-10 Finland
Low back pain
1.5
10.0
502
3867
212
Kela drug reimbursment
Gout
4.2
9.9
26
63
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
9.9
348
2494
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
9.8
929
8032
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
8.8
9.8
20
23
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
9.8
149
863
L71.8
ICD-10 Finland
Other rosacea
3.7
9.7
30
82
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
9.7
489
3764
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
9.7
533
4171
WZA00
NOMESCO Finland
Concise certificate
2.0
9.7
100
509
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
9.6
158
935
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
5.1
9.6
20
40
3005
Kela drug reimbursment
Tofacitinib
11.5
9.6
17
15
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.1
9.5
88
429
SPAT1283
SPAT
Restricted health certificate
1.6
9.5
229
1503
J01AA02
ATC
doxycycline; systemic
1.5
9.4
1037
9188
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.5
9.4
31
89
S29
ICPC
Skin symptom/complaint other
1.6
9.3
247
1660
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
9.3
116
631
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
9.2
329
2360
L60.0
ICD-10 Finland
Ingrowing nail
2.3
9.2
72
328
R03AC02
ATC
salbutamol; inhalant
1.4
9.2
721
5995
N07BA03
ATC
varenicline; oral
2.1
9.1
84
409
C07AB07
ATC
bisoprolol; oral
1.4
9.1
561
4467
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
4.0
9.1
25
63
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
9.1
596
4801
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.0
9.1
94
479
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.5
9.0
56
230
4AA12, ,
NOMESCO Finland
10.1
9.0
17
17
162
Kela drug reimbursment
liraglutide
4.1
9.0
24
59
L73.2
ICD-10 Finland
Hidradenitis suppurativa
3.9
9.0
26
68
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
9.0
715
5952
NF1DA
NOMESCO Finland
X-ray of hips
3.4
8.9
32
97
M10.0
ICD-10 Finland
Idiopathic gout
2.6
8.9
51
202
M01AH01
ATC
celecoxib; oral
1.6
8.8
208
1357
R60.0
ICD-10 Finland
Localized oedema
1.8
8.8
143
844
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
8.8
756
6366
B03BA03
ATC
hydroxocobalamin; parenteral
2.4
8.8
60
258
M01CB03
ATC
auranofin; oral
9.5
8.8
17
18
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
8.7
192
1231
A10BX07
ATC
[U] liraglutide
3.9
8.7
25
65
D01AE15
ATC
terbinafine; topical
2.0
8.7
98
515
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.5
8.6
53
217
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.9
8.5
110
605
WQ021, ,
NOMESCO Finland
27.7
8.5
11
*
RF410, ,
NOMESCO Finland
4.2
8.5
22
53
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
8.4
138
816
H01
ICPC
Ear pain/earache
1.7
8.4
150
910
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
8.3
985
8723
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.1
8.2
34
113
M01AE02
ATC
naproxen; oral, rectal
1.4
8.2
742
6274
SPAT1255
SPAT
Intravenous administration of medicine
2.0
8.2
85
434
OAB50, ,
SPAT
1.8
8.1
114
644
M01AB05
ATC
diclofenac; systemic, rectal
1.4
8.1
904
7901
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.9
8.1
110
615
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
3.7
8.0
25
69
RS221, ,
NOMESCO Finland
3.6
8.0
26
74
J01CA04
ATC
amoxicillin; systemic
1.5
8.0
1109
10062
R21
ICPC
Throat symptom/complaint
1.5
7.9
265
1870
H60.1
ICD-10 Finland
Cellulitis of external ear
3.7
7.9
24
65
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
7.9
91
482
XQ899
NOMESCO Finland
Other assessment of skin
7.8
7.9
17
22
SPAT1153
SPAT
Removal of sutures
1.4
7.9
360
2704
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.8
493
3916
K05.30
ICD-10 Finland
Periodontitis complex
1.6
7.8
204
1362
H02AB09
ATC
hydrocortisone; systemic
2.9
7.8
36
127
D07XB02
ATC
triamcinolone; topical
3.8
7.8
23
61
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
7.8
80
407
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
7.7
103
572
J01DA09
ATC
[U] cefadroxil
1.5
7.7
337
2507
A02BA02
ATC
ranitidine; systemic
1.6
7.7
210
1416
Z22.30
ICD-10 Finland
Latent tuberculosis
45.2
7.7
9
*
A10BB12
ATC
glimepiride; oral
2.1
7.7
69
333
RF420, ,
NOMESCO Finland
3.8
7.6
23
62
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
7.6
136
824
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
7.6
117
679
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
7.6
449
3524
R06.0
ICD-10 Finland
Dyspnoea
1.5
7.6
313
2302
L20.0
ICD-10 Finland
Besnier prurigo
1.8
7.6
103
576
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.1
7.5
69
336
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
7.5
138
844
J01FA09
ATC
clarithromycin; systemic
1.4
7.5
397
3058
R05
ICPC
Cough
1.5
7.5
300
2196
XX9XT
NOMESCO Finland
Other radiological intervention
80.5
7.4
8
*
L99
ICPC
Musculoskeletal disease other
2.9
7.4
34
120
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.6
7.4
161
1029
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.6
7.4
42
166
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.4
337
2526
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
7.3
307
2265
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
7.3
172
1121
L04AC17
ATC
tildrakizumab; parenteral
+∞
7.3
7
*
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.4
7.3
404
3133
D11AH01
ATC
tacrolimus; topical
4.2
7.3
19
46
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
7.3
64
307
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.9
7.3
91
496
E66.9
ICD-10 Finland
Obesity, unspecified
2.3
7.2
54
242
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
7.2
62
295
K05.31
ICD-10 Finland
Periodontitis pronounced
1.6
7.2
151
956
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.2
468
3728
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.0
7.2
78
405
D07AC04
ATC
fluocinolone acetonide; topical
20.1
7.1
10
5
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.4
7.1
49
212
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.3
7.0
51
226
L28
ICPC
Limited function/disability (L)
1.6
7.0
186
1246
J01FA06
ATC
roxithromycin; oral
1.4
7.0
485
3899
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.6
7.0
38
147
SPAT1325
SPAT
Vaccination
1.4
6.9
333
2515
R03BA05
ATC
fluticasone; inhalant
1.5
6.9
215
1492
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
7.6
6.9
15
20
XQ902
NOMESCO Finland
Other photography
4.0
6.9
19
48
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
6.9
165
1079
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
6.9
362
2780
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
8.3
6.8
14
17
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
6.8
145
921
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
9.4
6.8
13
14
Z01.2
ICD-10 Finland
Dental examination
1.3
6.8
605
5051
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.2
6.7
26
83
J02AC02
ATC
itraconazole; systemic
1.5
6.7
207
1436
A10BX04
ATC
[U] exenatide
3.7
6.6
20
54
RS121, ,
NOMESCO Finland
6.5
6.6
16
25
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.3
6.6
48
213
E0001A1, ,
ATC
2.9
6.6
29
100
A10BG03
ATC
pioglitazone; oral
2.7
6.6
35
134
SPAT1281
SPAT
Other administrative function
1.8
6.6
91
513
WX723
NOMESCO Finland
CPAP therapy
2.0
6.5
73
383
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
3.8
6.5
19
50
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
6.5
284
2106
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
6.5
131
821
A77
ICPC
Viral disease other/NOS
2.3
6.5
46
202
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
3.7
6.5
20
55
ZX120
NOMESCO Finland
Intravenous
1.7
6.5
108
643
M01CB01
ATC
sodium aurothiomalate; parenteral
5.3
6.5
18
34
L08.0
ICD-10 Finland
Pyoderma
5.3
6.5
18
34
ZX140
NOMESCO Finland
Intra articular
5.3
6.5
18
34
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
1.9
6.5
75
399
M17.5
ICD-10 Finland
Other secondary gonarthrosis
3.2
6.5
25
80
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.7
6.5
127
791
M79.7
ICD-10 Finland
Fibromyalgia
2.4
6.5
44
190
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.4
6.4
22
65
WXQ26
NOMESCO Finland
UVB broad spectrum light therapy
70.2
6.4
7
*
A41.9
ICD-10 Finland
Sepsis, unspecified
2.3
6.4
45
197
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.6
6.4
35
136
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
6.4
82
451
UJF32
NOMESCO Finland
Coloscopy
1.4
6.4
289
2157
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
6.3
129
811
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
5.2
6.3
18
35
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
2.6
6.3
34
131
J01FA01
ATC
erythromycin; systemic
1.6
6.3
167
1118
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.4
6.3
355
2751
SCA01
NOMESCO Finland
Preventive oral health care, short
1.4
6.3
352
2725
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.4
6.3
43
186
C09DA07
ATC
telmisartan and diuretics; oral
2.2
6.3
50
231
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
18.1
6.3
9
5
M07
ICD-10 Finland
Psoriatic and enteropathic arthropathies
+∞
6.3
6
*
M073, L400,
ICD-10 Finland
+∞
6.3
6
*
WQ032, ,
NOMESCO Finland
+∞
6.3
6
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
6.2
99
581
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
7.1
6.2
14
20
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.8
6.2
91
522
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
3.7
6.2
19
52
B07.9
ICD-10 Finland
Verruca simplex
2.1
6.2
53
252
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
6.3
6.2
15
24
N05CF02
ATC
zolpidem; oral
1.5
6.1
216
1538
E66.0
ICD-10 Finland
Obesity due to excess calories
4.1
6.1
16
39
A10AB05
ATC
insulin aspart; parenteral
1.7
6.1
100
593
SPAT1147
SPAT
Destruction of skin lesion with external methods
3.0
6.1
25
83
L04AA44
ATC
[U] upadacitinib
12.6
6.1
10
8
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
8.6
6.1
12
14
L04AA17
ATC
[U] adalimumab
8.6
6.1
12
14
NF1AA
NOMESCO Finland
Hip X-ray examination
1.8
6.0
91
527
C03DA01
ATC
spironolactone; oral
1.6
6.0
127
806

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
725
1782
7.26
309.42
1.4
1.4
400.28
498.40
titre
0.74
143
363
586
1082
8.51
307.65
1.3
1.6
—
—
—
0
0
1333
6278
18.76
277.39
17.3
6.4
0.60
0.58
e9/l
5.13
1306
5435
1333
6285
18.72
276.82
17.3
6.5
0.05
0.04
e9/l
7.71
1307
5441
1333
6420
18.02
266.20
17.4
6.5
2.03
1.97
e9/l
0.72
1312
5709
1334
6497
17.84
261.06
17.5
6.8
0.21
0.19
e9/l
4.67
1309
5717
361
507
9.20
255.75
1.5
1.7
7.03
6.93
iu/ml
0.02
44
124
1244
5759
10.22
251.67
17.7
6.7
9.02
8.84
%
1.69
1238
5439
1242
5748
10.13
251.09
17.4
6.6
3.13
2.86
%
4.75
1236
5419
1238
5740
9.90
248.78
17.7
6.7
0.81
0.69
%
16.68
1232
5407
1249
5917
10.08
242.68
17.4
6.6
29.98
28.20
%
9.80
1242
5652
699
2030
5.80
238.18
1.5
1.7
—
—
—
0
0
1011
4075
6.12
231.54
14.8
6.5
—
—
—
0
0
1339
7008
16.43
228.23
18.7
9.9
3.90
4.08
e9/l
3.37
1311
6099
590
1620
5.51
210.63
1.4
1.7
—
—
—
0
0
453
1021
6.04
201.20
6.7
4.7
0.03
0.12
%
3.03
101
288
449
1018
5.98
197.84
6.1
4.5
0.36
0.68
%
2.85
100
316
461
1073
5.88
197.30
6.6
4.6
0.47
1.00
%
4.40
108
340
446
1031
5.84
191.83
7.1
5.0
0.03
0.13
%
1.21
92
259
116
32
39.38
188.20
1.6
1.2
9.24
9.42
ug/l
0.08
116
32
128
54
25.95
181.38
1.8
1.6
1800.00
3221.82
titre
—
10
11
707
2554
4.51
172.67
1.6
1.9
—
—
—
0
0
749
2949
4.25
159.69
9.8
4.7
—
—
—
0
0
1312
8896
7.09
110.27
9.2
4.1
12.30
10.47
mm/h
5.45
1285
8402
974
5458
3.49
106.25
21.6
11.1
0.00
0.00
e9/l
1.15
935
4476
1333
9301
7.85
104.53
14.3
8.3
78.62
78.05
u/l
0.24
1322
8912
142
201
7.74
96.74
3.0
3.7
3.98
4.34
e9/l
0.98
142
201
209
469
5.05
88.77
1.4
1.2
—
—
—
0
0
130
184
7.68
88.43
1.1
1.2
—
—
—
0
0
210
488
4.88
85.43
1.1
1.2
1.36
0.97
u/ml
—
7
34
415
1576
3.31
83.83
3.3
3.5
5.43
5.16
e9/l
0.10
380
1404
147
261
6.17
80.53
3.1
3.5
55.21
58.11
%
1.97
147
261
1018
6419
3.06
79.83
5.3
3.5
0.01
0.27
estimate
0.50
307
1180
1008
6332
3.03
79.40
5.2
3.4
0.00
0.00
estimate
0.50
335
1284
1012
6384
3.03
78.83
5.3
3.4
0.00
6.32
estimate
1.58
337
1297
1166
8030
3.50
76.57
6.1
4.1
—
3.51
—
0
14
66
43
16.05
76.38
1.5
2.4
6.91
9.87
mg/l
2.12
47
35
634
3414
2.55
63.04
5.5
3.6
0.00
0.01
estimate
1.54
310
1196
70
74
9.90
59.91
1.1
1.1
1158.17
1525.09
miu/ml
1.97
70
74
365
1567
2.79
56.64
1.6
1.5
—
—
—
0
0
600
3311
2.40
54.59
3.0
2.8
346.73
347.39
umol/l
0.06
562
2994
795
5141
2.24
47.58
4.6
3.1
6.18
6.15
ph
0.28
458
3040
425
2128
2.42
46.79
1.4
1.3
6.91
10.99
u/ml
0.69
173
876
705
4392
2.20
45.70
4.5
3.8
63.94
73.74
e6/l
0.18
538
3086
119
291
4.37
44.67
1.2
1.2
52.50
47.14
u/ml
—
5
29
134
359
4.02
44.53
1.2
1.2
7.07
2.54
u/ml
—
6
28
134
360
4.01
44.35
1.2
1.2
5.42
8.08
u/ml
0.28
12
54
124
316
4.20
44.09
1.6
1.3
—
—
—
0
0
62
91
7.08
40.51
1.8
1.4
42.76
32.31
%
0.95
34
64
743
4895
2.08
39.74
5.6
3.3
0.00
0.02
estimate
1.87
291
1076
467
2608
2.18
38.38
3.4
2.6
5.03
5.05
e6/l
0.01
445
2390
266
1169
2.57
37.98
3.0
2.4
0.22
0.22
g/l
0.12
254
1101
412
2203
2.22
37.64
3.7
2.8
556.05
544.91
mosm/kgh2o
0.46
382
1942
67
117
5.96
37.01
2.0
1.6
47.32
58.46
%
1.04
38
81
132
397
3.56
36.97
1.2
1.3
210.00
100.98
titre
0.57
13
41
611
3825
2.05
36.70
3.8
3.2
40.06
93.88
e6/l
1.07
516
2904
304
1447
2.40
36.40
2.1
1.7
—
—
—
0
0
584
3613
2.05
36.09
4.6
2.9
0.04
0.04
estimate
0.02
285
1027
881
6353
2.02
34.74
6.2
7.0
11.74
11.74
umol/l
0.00
847
6106
579
3646
1.99
33.38
12.2
6.2
—
—
—
0
0
1375
12129
4.96
31.74
23.7
14.6
16.88
23.79
mg/l
21.27
1256
9882
447
2608
2.04
31.61
1.6
1.5
3.24
2.47
g/l
7.86
310
1715
221
970
2.51
31.25
2.7
2.5
0.20
0.44
e6/l
1.34
212
927
413
2353
2.06
31.10
1.4
1.3
22.39
28.06
iu/ml
0.78
105
710
604
3952
1.92
30.32
4.8
4.3
10.51
8.74
mg/mmol
0.39
414
2563
209
931
2.46
28.49
4.7
3.6
—
—
—
0
0
731
5162
1.86
28.28
5.0
5.5
35.56
36.27
g/l
2.68
693
4896
587
3889
1.87
27.66
3.8
3.6
65.06
51.32
mg/l
0.66
403
2609
153
596
2.76
27.39
2.2
2.3
0.00
1.32
estimate
0.51
47
192
627
4277
1.83
26.61
3.7
3.6
8.18
8.34
mmol/l
0.33
538
3702
512
3284
1.87
26.44
3.6
3.1
0.32
0.41
e6/l
0.58
426
2367
226
1076
2.31
26.40
2.1
2.1
0.02
0.02
estimate
0.09
65
248
71
175
4.22
26.28
1.9
4.0
0.82
1.68
%
1.59
61
165
184
812
2.45
25.47
1.5
1.8
1.26
1.29
g/l
0.08
174
762
642
4464
1.80
25.14
4.1
3.5
40.64
35.31
u/l
1.01
615
4233
103
340
3.19
24.76
1.1
1.3
—
—
—
0
0
732
5348
1.76
23.69
2.9
2.4
73.16
75.05
nmol/l
1.01
687
4916
53
114
4.79
23.25
1.6
1.3
17511.80
127694.05
e6/l
1.08
40
79
93
300
3.25
23.21
2.0
1.6
10760.31
12120.74
e6/l
0.11
75
216
455
2922
1.82
22.69
1.4
1.3
2.00
1.68
u/ml
0.18
153
877
484
3177
1.79
22.37
4.7
4.5
—
—
—
0
0
315
1816
1.94
21.91
2.3
2.6
2.44
2.34
g/l
2.12
292
1692
208
1034
2.18
21.65
1.9
2.8
11.93
10.69
g/l
2.56
193
965
238
1247
2.09
21.63
2.7
3.0
1.82
1.81
%
0.07
221
1134
330
1941
1.91
21.58
2.5
2.6
13.09
14.02
umol/l
1.46
313
1821
306
1766
1.93
21.14
2.3
2.2
—
—
—
0
0
715
5309
1.70
20.82
11.6
12.9
1.15
1.20
inr
2.11
611
4391
73
219
3.46
20.44
5.4
4.0
—
—
—
0
0
442
2902
1.76
19.96
3.3
2.8
—
—
—
0
0
926
7430
1.71
19.63
5.1
4.1
1704.76
1199.21
e6/l
0.19
21
112
553
3877
1.70
19.63
3.0
2.8
74.61
61.66
u/l
0.28
517
3655
288
1668
1.91
19.54
2.4
2.6
22.28
24.17
%
1.40
267
1570
188
941
2.15
19.13
2.1
3.1
74.59
72.12
e9/l
0.47
151
686
436
2897
1.73
18.64
2.8
2.2
3.13
2.74
mg/l
2.75
386
2509
154
733
2.23
17.72
1.7
2.7
—
—
—
0
0
414
2754
1.71
17.42
5.3
3.3
1.29
0.14
—
7
21
500
3528
1.64
16.64
3.6
2.6
0.14
0.04
0.47
14
50
736
5705
1.60
16.62
7.1
7.9
1.21
1.21
mmol/l
0.24
633
4985
873
7051
1.62
16.57
5.6
5.6
6.94
6.71
mmol/l
2.25
835
6717
68
233
3.01
15.35
1.1
1.1
46.94
125.68
iu/ml
0.68
14
53
174
918
2.02
15.26
1.7
3.0
68.40
67.06
g/l
1.26
159
861
79
296
2.77
15.17
2.3
3.5
2.79
2.21
index
0.13
29
174
268
1636
1.79
15.01
2.5
2.7
122.14
130.38
ug/g
0.17
219
1348
114
518
2.31
14.61
1.1
1.1
—
—
—
0
0
162
847
2.03
14.55
3.3
4.1
1.22
1.23
mmol/l
0.44
140
740
597
4501
1.56
14.53
4.0
3.5
32.37
53.84
ng/l
0.82
417
3014
95
402
2.46
14.28
2.1
2.5
93.56
5585.62
u/l
3.07
28
169
1064
9180
1.63
13.97
5.1
3.4
71.45
50.02
u/l
6.63
1016
8794
1383
13030
3.18
12.98
29.6
11.4
34.82
28.81
u/l
25.24
1378
12751
337
2271
1.63
12.92
2.0
1.7
182746917.15
30534776.15
pmol/l
0.94
284
1965
41
114
3.67
12.92
2.2
4.0
54.60
54.86
%
0.03
35
105
42
119
3.61
12.87
2.2
4.2
—
—
—
0
0
1276
11646
1.93
12.81
8.3
5.9
40.50
38.99
mmol/mol
7.01
1222
11105
83
355
2.42
12.21
1.6
4.1
54.20
61.42
mg/l
0.15
62
295
83
355
2.42
12.21
1.6
4.1
59.86
76.80
mg/l
0.20
64
296
1286
11819
1.91
11.87
6.3
4.2
1.54
1.35
mmol/l
12.23
1230
11114
306
2071
1.61
11.37
2.9
3.8
0.80
0.82
mmol/l
1.56
289
1977
75
322
2.40
10.96
1.6
3.9
1.21
2.25
ratio
2.34
43
174
22
43
5.18
10.80
1.8
2.7
209.20
41.65
au/ml
—
5
10
65
263
2.54
10.78
3.0
2.9
1.39
1.61
mmol/l
1.54
65
255
92
436
2.19
10.68
1.2
1.3
218.34
217.76
miu/ml
0.00
28
199
253
1657
1.64
10.68
1.2
1.2
—
—
—
0
0
192
1184
1.72
10.15
3.4
3.7
5.71
5.86
kpa
1.38
187
1151
193
1193
1.71
10.12
3.5
3.7
7.39
7.38
ph
1.00
130
677
1327
12427
2.01
10.05
7.2
5.0
4.60
4.69
mmol/l
2.39
1281
11824
186
1141
1.72
10.02
3.5
3.7
1.81
1.78
mmol/l
0.02
154
979
190
1175
1.71
9.94
2.5
2.3
321.62
372.36
nmol/l
3.84
178
1115
1270
11743
1.76
9.87
5.9
4.8
6.19
5.94
mmol/l
9.57
1203
10989
130
721
1.88
9.79
2.1
1.8
0.39
0.33
mg/l
0.51
73
376
139
792
1.84
9.62
3.3
3.5
5.28
5.14
kpa
1.11
131
770
43
151
2.91
9.38
1.3
1.2
—
—
—
0
0
53
208
2.61
9.38
3.2
3.1
7.45
7.51
mmol/l
0.05
53
201
246
1651
1.59
9.31
2.0
1.7
1101.79
1175.67
nmol/l
0.69
196
1292
414
3108
1.47
9.28
2.0
1.6
19.63
19.93
nmol/l
0.14
360
2692
135
772
1.83
9.23
3.2
3.5
7.41
7.42
ph
1.15
107
651
59
247
2.45
9.14
1.1
1.1
—
—
—
0
0
621
5040
1.41
9.04
2.3
2.0
93.90
96.20
pmol/l
0.65
390
2801
119
660
1.88
8.96
1.2
1.2
—
—
—
0
0
67
300
2.29
8.94
1.3
2.3
1.01
0.92
nmol/l
0.43
55
262
23
55
4.23
8.93
2.3
3.1
7.55
9.03
mg/l
0.32
12
49
1312
12315
1.84
8.76
20.6
16.8
139.41
139.73
mmol/l
5.56
1290
12120
1314
12350
1.84
8.58
20.8
17.0
3.98
3.97
mmol/l
0.80
1290
12126
59
256
2.36
8.47
1.1
1.1
—
—
—
0
0
216
1450
1.58
8.11
1.4
1.4
—
—
—
0
0
375
2826
1.44
8.06
5.8
3.4
1.02
1.02
kg/l
1.73
286
1884
52
219
2.43
7.99
1.2
1.8
—
—
—
0
0
412
3165
1.42
7.96
3.1
3.2
909.80
1081.83
ng/l
0.72
341
2677
90
474
1.96
7.93
1.9
2.0
2.96
1.90
ug/l
0.28
77
430
149
918
1.70
7.87
1.6
1.3
484.05
238.55
u/ml
1.13
141
862
76
378
2.07
7.85
1.4
2.7
11.77
10.35
g/l
1.07
66
348
681
5718
1.37
7.63
3.3
3.0
141.72
136.45
ug/l
0.27
642
5411
1204
11134
1.53
7.60
5.5
4.9
1.80
1.86
mu/l
1.21
1136
10441
283
2043
1.48
7.55
3.0
2.8
0.75
0.94
e6/l
0.83
176
1048
74
372
2.04
7.44
1.5
1.4
0.26
0.25
g/l
0.58
74
358
1311
12387
1.74
7.38
6.4
4.9
1.33
1.41
mmol/l
11.01
1252
11719
75
385
2.00
7.13
1.5
1.4
1.28
1.22
g/l
1.01
75
369
38
146
2.65
7.08
3.1
2.9
—
—
—
0
0
1322
12547
1.76
6.96
7.0
5.5
2.75
2.79
mmol/l
0.94
1261
11891
210
1452
1.52
6.87
3.2
3.1
8.95
8.04
umol/l
0.20
190
1291
611
5103
1.35
6.84
6.6
7.3
1.21
1.21
mmol/l
0.06
573
4771
63
309
2.09
6.78
6.2
3.3
46.25
33.68
umol/l
1.17
56
287
45
193
2.38
6.69
4.3
3.5
16.48
24.71
u/ml
0.14
45
188
429
3402
1.37
6.67
3.6
4.4
7.40
7.40
ph
0.01
312
2418
1025
9295
1.37
6.39
4.4
4.1
14.63
14.66
pmol/l
0.12
945
8652
227
1621
1.48
6.33
4.8
6.7
1.05
1.02
mmol/l
0.63
217
1515
35
137
2.59
6.31
1.7
2.7
33.00
32.69
pg
0.13
35
137
361
2811
1.38
6.22
1.6
1.8
1.26
1.09
mg/l
0.35
280
2137
459
3714
1.35
6.19
2.3
2.3
202.99
243.12
u/l
0.49
438
3556
76
413
1.89
6.16
3.3
2.5
25.81
24.67
mmol/l
1.75
76
408
26
89
2.96
6.01
1.4
1.7
—
—
—
0
0
35
141
2.52
5.97
1.9
2.7
1.01
0.94
%
0.31
26
97
180
1243
1.51
5.91
1.8
1.8
—
—
—
0
0
14
22
6.42
5.86
1.1
1.1
—
—
—
0
0
81
458
1.81
5.81
1.6
1.7
21.08
12.38
u/ml
0.63
13
122
76
423
1.84
5.73
3.7
4.1
367.19
416.96
mg/l
0.12
42
210
91
543
1.72
5.45
3.4
3.8
—
—
—
0
0
162
1115
1.51
5.40
6.5
8.6
11.21
8.89
mmol/l
3.08
156
1074
26
95
2.77
5.38
1.2
1.1
117.65
108.20
pmol/l
0.45
26
95
1324
12691
1.62
5.14
20.5
12.8
—
—
—
0
0
83
494
1.72
5.03
1.7
2.1
1.55
1.53
g/l
0.06
68
439
79
464
1.74
5.02
1.3
1.2
—
—
—
0
0
31
131
2.40
4.83
1.6
1.6
1.21
1.25
promille
0.06
25
104
1385
13477
2.04
4.65
42.0
21.9
253.26
249.58
e9/l
1.31
1380
13271
15
35
4.32
4.63
1.1
1.0
—
—
—
0
0
15
35
4.32
4.63
1.1
1.0
—
—
—
0
0
15
35
4.32
4.63
1.1
1.0
—
—
—
0
0
22
80
2.78
4.62
1.8
2.1
73.41
73.41
%
0.00
22
75
27
110
2.48
4.56
1.0
1.1
—
—
—
0
0
1385
13485
2.01
4.51
41.9
21.8
4.59
4.61
e12/l
0.64
1379
13251
1385
13489
2.00
4.44
42.0
21.9
6.98
6.67
e9/l
7.98
1380
13251
63
362
1.77
4.35
1.4
1.4
255.28
278.19
ug/g
0.45
39
212
640
5611
1.26
4.28
3.9
3.0
—
—
—
0
0
28
120
2.36
4.26
12.9
7.5
7.91
7.09
mmol/l
0.53
23
100
28
122
2.32
4.12
1.2
1.1
—
—
—
0
0
119
820
1.49
3.98
3.2
4.2
76.48
85.84
ng/l
0.57
99
736
39
198
2.00
3.95
1.4
1.4
58.88
61.24
mmol/l
0.14
24
169
34
164
2.10
3.94
1.9
2.0
1.91
1.65
mmol/l
1.45
34
159
11
23
4.81
3.87
1.4
1.0
—
—
u/ml
—
0
0
17
60
2.86
3.80
2.2
1.6
—
—
—
0
0
14
44
3.20
3.78
2.0
2.0
27.29
31.82
%
0.45
14
44
540
4693
1.24
3.77
2.0
2.0
—
—
—
0
0
241
1895
1.33
3.75
3.0
3.0
1.92
1.62
e6/l
0.33
131
901
116
1633
0.68
3.75
1.3
1.4
—
—
—
0
0
69
429
1.64
3.63
3.3
3.9
24.17
24.87
mmol/l
1.41
63
406
46
257
1.82
3.54
3.8
3.6
—
—
—
0
0
36
188
1.94
3.40
1.4
1.2
—
—
—
0
0
26
120
2.19
3.39
1.1
1.3
6.62
6.53
g/l
0.04
19
91
24
109
2.22
3.26
1.8
2.5
910.21
1324.01
e6/l
2.34
24
100
114
815
1.43
3.20
1.3
1.2
—
—
—
0
0
23
104
2.23
3.16
1.2
1.1
—
—
—
0
0
40
223
1.82
3.13
1.4
1.6
1.18
0.76
g/l
0.46
32
184
45
261
1.75
3.09
2.1
2.1
125.30
131.27
g/l
1.08
37
207
17
68
2.52
3.04
1.1
1.1
168.79
205.14
iu/ml
0.28
17
68
56
347
1.64
3.03
1.8
1.3
—
4.18
—
0
5
7
12
5.86
3.02
1.0
1.0
—
—
—
0
0
25
120
2.10
2.99
1.1
1.3
2.97
2.98
g/l
0.01
18
90
25
120
2.10
2.99
1.1
1.3
0.43
0.37
g/l
0.48
19
90
23
108
2.15
2.91
1.1
1.3
0.96
1.20
u/ml
—
10
58
22
103
2.15
2.81
2.5
2.8
1546.18
1164.23
mg
0.34
22
103
131
983
1.37
2.80
1.2
1.2
—
—
—
0
0
5
6
8.36
2.75
1.2
1.0
—
—
—
0
0
366
3141
1.22
2.73
5.2
4.3
89.49
91.55
%
0.87
356
3086
24
118
2.05
2.72
1.1
1.4
—
—
—
0
0
38
219
1.76
2.70
4.7
4.6
2.04
2.51
mmol/l
0.65
27
146
12
295
0.40
2.70
1.3
1.2
—
—
—
0
0
66
440
1.52
2.66
2.8
3.1
1.37
1.42
mg/l
0.24
61
408
605
5455
1.19
2.65
2.5
1.9
1.64
1.43
mmol/l
4.60
522
4730
12
41
2.94
2.62
2.6
2.1
137.83
2444.13
e6/l
—
6
23
121
910
1.36
2.57
2.8
2.1
5.91
6.07
ph
0.77
82
585
39
232
1.70
2.51
4.6
3.5
22.28
25.22
mg/l
0.26
33
159
36
213
1.71
2.37
1.2
1.2
—
—
—
0
0
16
71
2.27
2.34
1.8
1.5
1.44
1.27
nmol/l
—
10
55
8
23
3.49
2.27
2.1
3.1
—
—
—
0
0
130
1019
1.30
2.12
4.7
4.4
7.39
7.35
ph
3.49
98
767
95
714
1.35
2.07
3.8
3.8
24.08
24.17
mmol/l
0.08
95
707
7
20
3.51
2.05
1.3
1.1
0.03
0.02
u/ml
—
7
20
71
509
1.42
2.05
2.5
2.2
—
—
—
0
0
36
223
1.63
2.04
2.4
3.5
8.98
8.93
pmol/l
0.01
36
223
22
118
1.88
2.02
1.5
2.5
—
—
—
0
0
14
63
2.23
2.01
2.1
3.0
15.02
17.06
%
1.12
14
63
20
104
1.94
2.01
1.3
1.1
—
—
—
0
0
10
38
2.64
2.00
2.0
1.9
—
—
—
0
0
62
437
1.44
1.97
2.0
2.2
347.17
398.21
ug/l
0.16
57
414
21
113
1.87
1.92
2.2
2.7
—
—
—
0
0
18
93
1.95
1.85
1.2
1.1
340.45
412.67
nmol/l
0.56
11
85
21
115
1.84
1.83
1.4
1.1
—
—
—
0
0
65
472
1.40
1.78
2.1
3.5
—
—
—
0
0
19
102
1.87
1.76
3.5
3.1
130.10
15.44
mg/l
0.56
14
75
47
322
1.48
1.75
1.1
1.1
—
—
—
0
0
5
13
3.86
1.71
1.0
1.2
—
—
—
0
0
18
96
1.89
1.71
1.3
1.1
—
—
—
0
0
25
148
1.70
1.71
2.1
2.4
—
—
—
0
0
12
242
0.49
1.70
1.9
1.3
—
—
—
0
0
601
5570
1.14
1.61
2.9
2.8
—
—
estimate
—
0
0
13
63
2.07
1.60
1.5
2.0
80.30
98.89
ng/l
0.82
13
63
14
70
2.01
1.59
1.1
1.2
—
—
—
0
0
42
289
1.47
1.56
2.4
2.4
423.43
104.28
ug/min
0.92
20
185
423
3842
1.14
1.52
2.6
2.5
—
—
—
0
0
7
27
2.60
1.51
1.0
2.2
—
—
—
0
0
15
79
1.91
1.49
1.8
2.1
2.00
1.80
u/field
—
9
50
149
1245
1.22
1.47
9.6
10.5
95.23
95.72
%
0.42
143
1215
153
1813
0.83
1.46
2.1
2.1
4.09
3.68
ratio
2.84
120
1435
6
22
2.73
1.43
1.0
1.1
—
—
—
0
0
19
111
1.72
1.39
1.2
1.1
—
—
—
0
0
12
60
2.01
1.38
1.2
1.7
—
—
—
0
0
26
166
1.58
1.38
2.5
2.8
—
—
—
0
0
18
104
1.74
1.37
1.1
1.3
—
—
—
0
0
48
349
1.39
1.36
1.1
1.1
2.61
5.50
eliau/ml
—
7
53
15
82
1.84
1.36
1.1
1.0
—
—
—
0
0
51
681
0.74
1.32
1.1
1.1
1.38
1.49
g/l
2.93
51
681
87
694
1.27
1.32
1.5
2.3
—
—
—
0
0
11
207
0.53
1.31
1.6
1.5
—
—
—
0
0
26
391
0.66
1.31
1.5
1.6
—
—
—
0
0
104
849
1.24
1.30
1.1
1.2
93.80
153.15
u/ml
1.37
36
351
8
34
2.36
1.29
1.3
1.1
17.74
16.11
umol/l
—
8
29
11
205
0.53
1.28
1.6
1.5
1.15
1.30
mm
—
6
144
12
62
1.94
1.28
1.6
4.0
81.71
122.65
umol/l
—
7
34
61
468
1.32
1.25
1.7
1.8
—
—
—
0
0
12
215
0.55
1.23
1.6
1.6
—
—
—
0
0
49
649
0.75
1.22
1.0
1.1
0.74
0.68
ratio
—
10
66
14
78
1.80
1.21
1.6
2.8
209.07
227.61
e6/l
0.15
14
72
15
87
1.73
1.15
1.5
2.6
935.88
644.17
ml
—
8
58
7
30
2.34
1.12
3.3
3.2
37.29
5.13
ug/l
—
7
30
80
648
1.25
1.10
1.5
2.4
—
—
—
0
0
35
252
1.40
1.09
1.9
1.8
—
—
—
0
0
158
1373
1.17
1.06
9.4
10.2
7.41
7.41
ph
0.57
87
759
84
688
1.23
1.06
1.5
2.2
—
—
—
0
0
85
699
1.23
1.04
1.5
2.3
—
—
—
0
0
9
46
1.96
1.03
1.0
1.7
36.64
41.98
g/l
—
9
46
22
146
1.51
1.03
1.5
1.7
46.68
34.18
ng/l
0.23
22
146
13
75
1.74
1.03
1.6
1.3
—
—
—
0
0
62
493
1.27
1.01
1.3
1.2
—
—
—
0
0
85
702
1.22
1.00
1.5
2.3
—
—
—
0
0
16
99
1.62
1.00
1.1
1.3
2.06
1.98
mmol/l
0.20
16
91
26
181
1.44
0.98
1.3
1.8
—
—
—
0
0
157
1374
1.16
0.98
9.6
10.1
5.15
5.14
kpa
0.04
151
1333
5
23
2.18
0.98
2.0
2.3
—
—
—
0
0
157
1375
1.16
0.97
9.5
10.1
11.51
12.32
kpa
1.71
152
1338
117
1360
0.85
0.96
1.8
1.8
3.64
3.54
mmol/l
0.43
77
970
17
109
1.57
0.93
1.5
2.1
—
—
—
0
0
22
150
1.47
0.93
1.1
1.4
—
—
nmol/l
—
0
0
12
70
1.72
0.92
1.3
1.3
148.97
147.04
nmol/l
0.03
12
70
12
70
1.72
0.92
2.3
2.7
8.04
8.38
mmol/l
0.15
12
70
6
28
2.15
0.91
1.2
1.2
—
—
—
0
0
154
1362
1.15
0.85
9.4
10.1
0.36
0.98
mmol/l
1.05
127
1146
67
551
1.23
0.85
1.6
2.4
—
—
—
0
0
38
293
1.31
0.82
1.6
3.4
—
—
—
0
0
53
427
1.25
0.82
2.4
2.7
—
—
—
0
0
24
173
1.39
0.79
1.1
1.4
0.61
0.61
nmol/l
0.06
24
167
9
150
0.60
0.79
1.3
1.6
—
—
—
0
0
14
211
0.66
0.78
1.6
1.2
2.29
4.52
u/ml
—
7
89
0
26
0.00
0.78
0.0
3.2
—
—
—
0
0
104
902
1.17
0.76
2.2
2.4
16.43
22.00
au/ml
—
10
107
13
83
1.57
0.75
1.2
1.2
6.62
8.78
mm/h
0.77
13
83
38
298
1.28
0.74
1.3
1.5
—
—
—
0
0
111
971
1.16
0.74
2.4
2.3
5.10
8.06
ug/l
2.46
93
886
418
3940
1.09
0.73
2.6
3.5
2.35
2.35
mmol/l
0.40
390
3643
35
272
1.29
0.73
1.1
1.1
1.09
5.17
u/ml
3.43
22
147
19
265
0.71
0.73
1.5
1.5
54.11
59.53
ug/l
0.30
14
218
203
1851
1.11
0.71
2.0
2.3
30.02
29.47
s
0.76
198
1811
5
27
1.85
0.68
4.0
1.9
2.00
3.33
%
—
5
27
9
59
1.53
0.68
1.1
1.9
—
—
—
0
0
85
734
1.17
0.68
2.2
3.7
4.44
4.63
pmol/l
1.16
74
666
112
988
1.15
0.68
1.4
1.4
—
—
—
0
0
7
43
1.63
0.67
5.9
2.7
—
—
—
0
0
35
437
0.80
0.64
1.5
1.5
608.95
1012.13
mu/l
4.43
25
354
14
200
0.70
0.63
1.3
1.2
—
—
—
0
0
10
63
1.59
0.62
1.5
1.3
148.50
182.80
mmol/24h
—
10
63
29
368
0.78
0.61
8.6
9.3
—
—
—
0
0
5
30
1.67
0.61
1.2
1.4
—
—
—
0
0
149
1642
0.90
0.61
2.4
2.4
13.43
13.91
nmol/l
0.34
139
1529
13
88
1.48
0.60
1.3
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
10
150
0.66
0.58
1.2
1.5
216.20
229.78
pmol/l
—
10
150
118
1062
1.12
0.55
11.1
10.8
—
—
—
0
0
55
468
1.18
0.55
1.4
1.4
10.11
7.78
u/l
0.53
43
377
285
3028
0.93
0.54
2.3
3.0
0.57
0.71
ug/l
4.70
165
1757
384
3651
1.07
0.54
1.5
1.4
—
—
—
0
0
65
746
0.87
0.52
1.5
1.7
—
—
—
0
0
14
100
1.40
0.52
1.3
1.4
31804.29
36634.02
e6/l
—
7
50
6
40
1.50
0.51
1.2
1.4
—
—
—
0
0
9
64
1.41
0.51
1.0
1.1
—
12.50
—
0
6
32
260
1.24
0.51
1.1
1.1
0.47
1.38
u/ml
0.97
17
112
201
2158
0.92
0.50
2.5
3.0
2.46
2.44
mmol/l
2.32
188
1960
509
4898
1.06
0.49
4.0
4.7
1.46
2.08
ug/l
4.79
460
4510
67
763
0.87
0.49
2.2
2.9
114.53
164.40
ng/l
1.11
59
689
41
345
1.19
0.48
2.0
2.1
2.83
4.17
iu/l
1.11
18
143
14
102
1.38
0.47
1.2
1.1
—
—
—
0
0
5
83
0.60
0.45
50.4
39.5
7.30
7.45
ug/l
—
5
74
36
301
1.20
0.45
1.2
1.2
267.59
260.23
u/ml
0.07
29
187
11
152
0.72
0.44
2.8
2.2
—
—
—
0
0
20
158
1.27
0.42
1.2
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
11
79
1.40
0.40
1.6
2.7
309.27
627.00
e6/l
1.73
11
68
5
34
1.47
0.40
5.0
3.0
—
—
—
0
0
0
19
0.00
0.39
0.0
2.6
—
—
—
0
0
72
648
1.12
0.37
1.3
1.4
24.36
25.07
iu/l
0.07
62
551
6
43
1.40
0.35
1.8
2.8
0.57
0.60
mmol/l
—
6
43
10
74
1.35
0.32
2.7
3.5
730.00
1039.01
u/ml
—
10
74
6
47
1.28
0.32
1.7
1.4
5.60
6.29
mmol/l
—
6
47
156
1469
1.07
0.32
1.5
1.5
—
—
—
0
0
14
176
0.79
0.32
2.8
2.6
—
31.37
—
0
22
7
52
1.35
0.31
1.4
1.1
—
—
—
0
0
17
138
1.23
0.30
1.2
1.5
275.30
282.05
mosm/kgh2o
—
10
109
7
54
1.30
0.30
1.0
1.1
—
—
—
0
0
7
57
1.23
0.29
1.3
1.7
0.00
0.05
estimate
—
7
57
37
326
1.14
0.29
2.2
3.0
65.24
62.28
%
0.36
37
315
8
62
1.29
0.28
1.0
1.6
—
—
—
0
0
62
567
1.10
0.27
2.0
1.9
185.37
218.13
pmol/l
2.90
56
542
13
104
1.25
0.26
1.4
1.6
—
—
—
0
0
36
321
1.12
0.24
1.1
1.1
—
—
—
0
0
11
87
1.27
0.24
1.4
1.6
4.99
7.06
u/l
1.31
11
71
36
322
1.12
0.23
1.1
1.1
—
—
—
0
0
24
209
1.15
0.23
1.2
1.2
—
—
—
0
0
5
40
1.25
0.22
5.2
2.8
—
—
—
0
0
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
14
116
1.21
0.22
1.4
1.3
4948.78
1935.61
e6/l
—
9
72
0
11
0.00
0.21
0.0
1.4
—
408.09
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
16.96
—
0
12
29
258
1.13
0.21
1.1
1.1
0.12
1.89
u/ml
3.17
13
133
5
43
1.16
0.21
4.6
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
6
50
1.20
0.19
1.0
1.0
—
—
—
0
0
6
51
1.18
0.19
1.0
1.0
—
—
—
0
0
17
148
1.15
0.17
1.1
1.1
—
—
—
0
0
42
390
1.08
0.15
1.0
1.1
—
—
—
0
0
27
245
1.10
0.15
1.1
1.1
18.66
17.02
au/ml
—
5
76
23
207
1.11
0.15
1.1
1.5
0.25
0.33
nmol/l
0.45
16
168
27
296
0.91
0.15
1.4
1.4
48.56
24.58
e6/l
0.22
18
215
170
1650
1.03
0.14
1.7
1.4
—
—
—
0
0
23
208
1.11
0.14
1.1
1.1
2.44
2.18
eliau/ml
0.10
12
104
33
305
1.08
0.13
1.1
1.1
5.35
2.56
u/ml
0.23
17
170
161
1564
1.03
0.13
1.3
1.3
—
—
—
0
0
53
501
1.06
0.13
1.5
1.6
239.27
272.05
mu/l
0.75
45
461
22
200
1.10
0.12
1.1
1.0
0.50
0.40
u/ml
0.10
11
72
11
95
1.16
0.11
1.2
1.4
68.64
79.78
umol/l
0.97
11
95
300
2948
1.02
0.11
2.6
2.4
—
—
—
0
0
25
230
1.09
0.11
1.1
1.1
7.54
1.92
u/ml
0.65
14
118
14
124
1.13
0.11
1.9
2.4
7.51
6.52
umol/l
—
9
89
224
2283
0.98
0.10
3.6
3.7
691.93
569.00
ng/l
0.21
150
1699
116
1127
1.03
0.10
3.9
4.8
44.70
20.92
ug/l
0.25
95
916
28
300
0.93
0.10
1.4
1.4
1684.52
1499.01
e6/l
0.05
23
228
5
45
1.11
0.09
1.0
1.3
8.98
11.03
mmol/l
—
5
45
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
44
462
0.95
0.09
3.8
3.9
84.08
3114.13
u/ml
0.81
37
405
6
54
1.11
0.09
1.2
3.1
13.20
20.31
ug/l
—
6
48
12
107
1.12
0.08
1.4
1.4
—
—
—
0
0
5
61
0.82
0.08
1.6
1.5
27.40
29.26
umol/l
—
5
55
8
74
1.08
0.07
1.6
1.7
—
—
—
0
0
8
75
1.07
0.07
2.3
4.0
1.00
0.93
index
—
8
75
87
847
1.03
0.07
1.0
1.1
—
—
—
0
0
20
188
1.06
0.05
2.1
2.3
—
1454.55
—
0
11
23
219
1.05
0.04
1.1
1.1
0.41
3.95
u/ml
3.46
12
99
17
160
1.06
0.04
1.3
1.5
326.75
309.99
mu/l
0.14
12
129
118
1197
0.98
0.04
3.1
2.8
35.46
80.55
u/l
0.59
111
1031
12
111
1.08
0.04
1.2
1.2
—
—
—
0
0
21
218
0.96
0.02
1.5
1.4
109.00
226.23
pmol/l
0.81
21
212
27
277
0.97
0.01
1.2
1.4
—
—
—
0
0
15
144
1.04
0.00
1.7
2.1
12.34
11.08
%
0.42
15
144
16
164
0.98
0.00
1.9
1.8
—
—
—
0
0
10
98
1.02
0.00
1.5
1.3
—
—
—
0
0
14
143
0.98
0.00
1.2
1.3
—
—
—
0
0
17
173
0.98
0.00
1.2
1.6
—
—
—
0
0
17
173
0.98
0.00
1.2
1.6
—
—
—
0
0
17
173
0.98
0.00
1.2
1.6
—
—
—
0
0
17
173
0.98
0.00
1.2
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
182.20
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
61
0.98
-0.00
1.8
1.6
—
21.15
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
0.15
—
0
6
6
59
1.02
-0.00
4.2
4.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
86
0.93
-0.00
4.8
3.6
31.96
67.27
u/ml
—
8
86
0
8
0.00
-0.00
0.0
1.1
—
28.11
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
39
390
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.3
—
408.50
—
0
8
12
120
1.00
-0.00
1.8
1.4
2.21
2.99
ug/l
—
7
105
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
335.20
—
0
5
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint PSORI_STRICT and mortality.

Females

Parameter HR [95% CI] p-value
PSORI_STRICT 1.781 [1.33, 2.39] < 0.001
Birth year 0.994 [0.99, 1.0] 0.162

During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 1071 females with PSORI_STRICT died.

Males

Parameter HR [95% CI] p-value
PSORI_STRICT 1.697 [1.39, 2.07] < 0.001
Birth year 0.99 [0.98, 1.0] 0.047

During the follow-up period (1.1.1998 — 31.12.2019), 192 out of 2080 males with PSORI_STRICT died.

Mortality risk

Mortality risk for people of age

years, who have PSORI_STRICT.

N-year risk Females Males
1 0.142% 0.38%
5 1.044% 2.072%
10 2.618% 5.097%
15 5.037% 10.192%
20 8.678% 17.05%

Relationships between endpoints

Index endpoint: PSORI_STRICT – Psoriasis (vulgaris), strict definition

GWS hits: 10

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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