Psoriasis (vulgaris), strict definition

PSORI_STRICT

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • L12_PSORI_VULG
8558

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • KELA reimbursements: KELA codes 319|377|134

1 out of 7 registries used, show all original rules.

1313

4. Check minimum number of events

None

1313

5. Include endpoints

None

1313

6. Filter based on genotype QC (FinnGen only)

1266

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS
Control conditions
not L12_PSORI_VULG

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4808 1617 3168
Only index persons 4482 1538 2944
Unadjusted period prevalence (%)
Whole population 0.07 0.05 0.09
Only index persons 0.09 0.06 0.11
Median age at first event (years)
Whole population 51.67 54.18 50.42
Only index persons 51.17 53.78 49.80

-FinnGen-

Key figures

All Female Male
Number of individuals 1266 522 744
Unadjusted period prevalence (%) 0.28 0.19 0.34
Median age at first event (years) 52.08 53.54 51.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1313
Matched controls
13130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AA32
ATC
apremilast; oral
+∞
322.6
296
*
L01BA01
ATC
methotrexate; systemic
31.9
307.7
287
114
E000001, ,
ATC
15.8
307.7
856
1390
134
Kela drug reimbursment
General erythroderma
1610.6
307.7
354
*
TQW80
NOMESCO Finland
Local dermatologic skincare
29.9
307.7
255
105
E000002, ,
ATC
10.5
307.7
487
700
D07AC13
ATC
mometasone; topical
9.2
307.7
879
2360
L04AD01
ATC
ciclosporin; systemic
33.4
307.7
216
77
E0000UV, ,
ATC
49.6
307.7
1243
3461
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
82.8
307.7
249
37
L04AC05
ATC
ustekinumab; parenteral
322.4
307.7
259
10
D05AX03
ATC
calcitriol; topical
501.6
307.7
413
12
L40.5
ICD-10 Finland
Arthropathic psoriasis
1554.7
307.7
490
5
L40.9
ICD-10 Finland
Psoriasis, unspecified
219.5
307.7
304
18
D07AD01
ATC
clobetasol; topical
23.7
307.7
888
1065
L40.0
ICD-10 Finland
Psoriasis vulgaris
8636.0
307.7
1272
47
L40
ICD-10 Finland
Psoriasis
118.1
307.7
367
43
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
1512.7
307.7
539
6
L04AB04
ATC
adalimumab; parenteral
44.2
307.7
340
103
D05BB02
ATC
acitretin; oral
632.5
307.7
825
35
D05AX52
ATC
calcipotriol, combinations; topical
424.5
307.7
1119
176
S91
ICPC
Psoriasis
233.0
307.7
198
10
377
Kela drug reimbursment
Apremilast and dimethyl fumarate (psoriasis)
+∞
307.7
335
*
E000003, ,
ATC
20.0
307.7
333
219
L04AX03
ATC
methotrexate; systemic
112.3
307.7
1076
510
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
11.0
307.7
462
618
D07AC01
ATC
betamethasone; topical
22.6
307.7
1140
2964
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
+∞
307.7
904
*
D05AX02
ATC
calcipotriol; topical
266.7
307.7
837
86
D07XC01
ATC
betamethasone; topical
74.8
307.7
1062
703
D07AB02
ATC
hydrocortisone butyrate; topical
6.9
273.9
788
2335
L04AC18
ATC
risankizumab; parenteral
+∞
273.8
253
*
D07AB08
ATC
desonide; topical
8.7
271.7
430
698
D02AE01
ATC
carbamide; topical
10.8
252.1
309
364
L04AC10
ATC
secukinumab; parenteral
380.0
251.6
246
8
L04AC16
ATC
guselkumab; systemic
2688.2
251.2
235
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
703.8
243.4
233
*
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
6.1
235.3
648
1798
L04AC13
ATC
ixekizumab; parenteral
660.0
230.1
221
*
L04AB01
ATC
etanercept; parenteral
29.3
222.2
151
58
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
9.9
219.8
283
353
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
15.6
193.7
176
129
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
15.0
191.4
178
136
D02AX
ATC
Other emollients and protectives
15.5
191.1
174
128
L40.8
ICD-10 Finland
Other psoriasis
309.1
187.2
186
7
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.4
177.7
299
504
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
7.2
171.2
295
509
E000007, ,
ATC
9.3
169.7
223
282
XQ848
NOMESCO Finland
Dermatological photography
14.0
166.2
160
129
L04AA01
ATC
[U] ciclosporin
26.7
152.2
106
43
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
7.3
138.4
224
358
E000006, ,
ATC
7.3
134.7
218
348
A07EC01
ATC
sulfasalazine; oral, rectal
6.4
133.5
252
471
L04AA13
ATC
[U] leflunomide
15.3
131.1
118
84
D05AA
ATC
Tars
188.4
116.5
120
7
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
+∞
116.4
110
*
D09AB01
ATC
zinc bandage without supplements; topical
15.8
113.7
100
68
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
112.1
106
*
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
30.8
106.0
70
24
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
61.7
105.8
59
10
299, ,
Kela drug reimbursment
+∞
105.7
100
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
103.1
783
3962
L04AA11
ATC
[U] etanercept
53.1
97.6
56
11
L40.4
ICD-10 Finland
Guttate psoriasis
503.1
95.7
94
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.7
92.8
248
621
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
87.5
83
*
D07AA02
ATC
hydrocortisone; topical
3.7
82.3
318
1036
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.5
66.8
279
946
D05AX05
ATC
tazarotene; topical
615.3
60.2
59
*
L04AC21
ATC
bimekizumab; systemic
+∞
57.7
55
*
D07XB01
ATC
flumetasone; topical
23.6
53.9
39
17
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
9.4
52.8
64
71
L88
ICPC
Rheumatoid/seropositive arthritis
6.2
52.3
93
160
TQW99
NOMESCO Finland
Other minor procedure on skin
5.0
51.8
118
255
H02AB06
ATC
prednisolone; systemic
2.4
49.8
699
4283
NH3EA
NOMESCO Finland
Feet X-ray examination with load
8.7
47.5
61
73
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
46.3
644
3893
L40.1
ICD-10 Finland
Generalized pustular psoriasis
+∞
46.1
44
*
M07.0
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
452.5
44.5
44
*
6960A
ICD-9 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
44.0
42
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.9
41.2
132
370
L26
ICD-10 Finland
Exfoliative dermatitis
148.1
41.0
43
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
40.0
176
606
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
5.3
39.5
82
163
D05AC01
ATC
dithranol; topical
399.0
39.3
39
*
E000004, ,
ATC
6.7
38.6
62
96
D05AX
ATC
Other antipsoriatics for topical use
388.3
38.2
38
*
D07BC01
ATC
betamethasone and antiseptics; topical
2.8
37.7
211
830
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
7.1
37.5
57
83
A46
ICD-10 Finland
Erysipelas
2.7
36.7
236
997
L04AB06
ATC
golimumab; parenteral
10.8
35.0
38
36
D07AC14
ATC
methylprednisolone aceponate; topical
4.1
34.3
97
248
A10BA02
ATC
metformin; oral
2.2
34.1
403
2221
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
33.6
155
546
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
7.2
33.2
50
72
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.2
32.4
331
1715
J01DB01
ATC
cefalexin; oral
2.6
32.2
1137
9336
ZY010
NOMESCO Finland
Hospital outpatient
3.6
31.5
112
336
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
8.6
31.0
40
48
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
5.7
30.9
58
105
ZX112
NOMESCO Finland
Subcutaneous
6.0
30.7
55
95
T90
ICPC
Diabetes non-insulin dependent
2.2
30.7
334
1771
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.8
30.6
167
645
XQ802
NOMESCO Finland
Epicutan test
4.2
30.3
83
207
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
5.6
30.3
58
107
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
+∞
28.2
27
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.1
28.2
123
419
J01FF01
ATC
clindamycin; systemic
2.0
28.0
401
2345
A10BJ06
ATC
semaglutide; parenteral
3.3
27.2
108
347
E66.8
ICD-10 Finland
Other obesity
3.3
27.0
109
354
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
26.9
437
2665
N05BB01
ATC
hydroxyzine; systemic
3.3
26.8
108
350
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
26.7
351
1986
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
26.5
365
2100
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
25.6
282
1490
L04AB05
ATC
certolizumab pegol; parenteral
30.7
25.1
33
11
D07AC03
ATC
desoximetasone; topical
6.0
24.6
44
76
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
8.4
24.4
32
39
TNG10
NOMESCO Finland
Puncture of knee
8.0
24.3
33
42
E66.01
ICD-10 Finland
Obesity due to excess calories
2.6
24.1
151
623
M25.5
ICD-10 Finland
Pain in joint
1.9
24.1
457
2910
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
6.6
24.0
39
61
WZC30
NOMESCO Finland
Teaching
2.2
23.8
238
1208
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.0
23.7
109
382
D07CC01
ATC
betamethasone and antibiotics; topical
2.3
23.5
197
929
SPAT1262
SPAT
Handing over of treatment supplies
2.2
23.4
239
1223
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
5.8
22.5
41
72
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
8.5
22.3
29
35
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
6.6
22.3
36
56
SPAT1263
SPAT
Sampling
1.8
22.0
525
3564
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
21.5
508
3434
XQ845
NOMESCO Finland
Dermatoscopy
5.7
21.4
40
72
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.5
21.2
145
623
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
21.0
185
889
E66.00
ICD-10 Finland
Metabolic syndrome
2.9
20.8
105
387
ZXC50
NOMESCO Finland
Cryotherapy
4.5
20.5
50
114
R06AE07
ATC
cetirizine; oral
1.7
20.5
575
4068
L20
ICPC
Joint symptom/complaint NOS
4.0
20.4
59
153
D11AH04
ATC
alitretinoin; oral
48.8
20.2
24
5
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.8
20.2
46
99
RJ411, ,
NOMESCO Finland
16.4
20.2
32
20
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
20.1
168
789
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.4
20.0
146
646
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
+∞
19.8
19
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
19.4
305
1810
Z3231
NOMESCO Finland
Registered nurse
1.8
19.2
353
2199
D07AB01
ATC
clobetasone; topical
3.9
18.8
55
144
S18
ICPC
Laceration/cut
1.7
18.2
561
4031
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
18.1
187
956
RJ421, ,
NOMESCO Finland
20.4
17.8
26
13
WQ031, ,
NOMESCO Finland
+∞
17.7
17
*
69600
ICD-8 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
17.7
17
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
17.7
79
272
J01DA01
ATC
[U] cefalexin
1.7
17.5
794
6282
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
4.6
17.4
41
91
C08CA01
ATC
amlodipine; oral
1.7
16.9
435
2965
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.2
16.9
161
797
A02BC02
ATC
pantoprazole; systemic
1.7
16.9
847
6846
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
16.7
694
5340
XQ800
NOMESCO Finland
Prick test
2.5
16.7
112
477
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
7.4
16.6
24
33
M01AH05
ATC
etoricoxib; oral
1.7
16.4
835
6748
M04AA01
ATC
allopurinol; systemic
2.2
16.1
155
769
G47.3
ICD-10 Finland
Sleep apnoea
1.7
15.9
342
2213
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
15.9
169
871
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
3.7
15.7
50
139
L40.2
ICD-10 Finland
Acrodermatitis continua
+∞
15.7
15
*
L04AA21
ATC
[U] efalizumab
+∞
15.7
15
*
WQ053, ,
NOMESCO Finland
+∞
15.7
15
*
A10BH01
ATC
sitagliptin; oral
2.3
15.4
126
586
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.9
14.9
202
1134
WQ066, ,
NOMESCO Finland
81.0
14.6
16
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
14.4
107
476
S97
ICPC
Chronic ulcer skin
2.6
14.2
82
325
SPAT1312
SPAT
General health counselling
1.7
14.1
363
2454
T82
ICPC
Obesity
2.9
14.0
67
240
RS340, ,
NOMESCO Finland
30.4
13.9
18
6
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
13.9
453
3247
SPAT1301
SPAT
No procedures
1.7
13.9
344
2303
RJ420, ,
NOMESCO Finland
13.7
13.7
23
17
D05AD01
ATC
trioxysalen; topical
+∞
13.6
13
*
M07.1*L40.5
ICD-10 Finland
Arthritis mutilans
+∞
13.6
13
*
H02AB07
ATC
prednisone; oral
2.0
13.5
161
863
SPAT1254
SPAT
Administration of medicine
2.0
13.3
159
853
C03CA01
ATC
furosemide; systemic
1.7
13.3
267
1686
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
13.1
125
617
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.0
13.1
144
751
SPAT1310
SPAT
Counselling related to known health issue
1.6
13.0
361
2482
291
Kela drug reimbursment
Tofacitinib
19.3
12.9
19
10
S76
ICPC
Skin infection other
2.6
12.9
75
298
QXA70
NOMESCO Finland
Guidance related to rash and skin care
50.5
12.9
15
*
L30.3
ICD-10 Finland
Infective dermatitis
3.0
12.8
56
191
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
12.8
157
851
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
6.3
12.5
21
34
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.0
12.5
56
194
M10.9
ICD-10 Finland
Gout, unspecified
2.4
12.4
89
391
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
4.2
12.3
33
81
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.9
12.3
168
942
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
12.3
355
2456
D07XB05
ATC
dexamethasone; topical
3.7
12.2
39
109
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
12.0
432
3146
J01CE08
ATC
benzathine benzylpenicillin; parenteral
5.9
11.8
21
36
M13.9
ICD-10 Finland
Arthritis, unspecified
2.2
11.7
98
459
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
11.7
905
7732
J02AC01
ATC
fluconazole; systemic
1.6
11.7
428
3122
WZA10
NOMESCO Finland
Extensive medical or dental certificate
4.2
11.6
31
76
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
11.6
324
2220
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
5.3
11.6
23
44
160
Kela drug reimbursment
exenatide
3.6
11.5
38
109
205
Kela drug reimbursment
Chronic hypertension
1.7
11.5
260
1691
212
Kela drug reimbursment
Gout
4.7
11.4
26
56
SPAT1260
SPAT
Consultation of another employee
1.8
11.4
193
1158
L30.8
ICD-10 Finland
Other specified dermatitis
3.3
11.3
43
135
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
11.3
128
674
NG1DA
NOMESCO Finland
X-ray of knees
4.4
11.3
28
65
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
5.0
11.2
24
49
WW200
NOMESCO Finland
Immunization
3.0
11.1
48
163
R4180
NOMESCO Finland
Podiatric therapy
4.7
11.0
25
54
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
10.9
304
2078
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
10.9
220
1386
L71.8
ICD-10 Finland
Other rosacea
4.2
10.8
28
67
EBA00
NOMESCO Finland
Extraction of tooth
1.5
10.8
444
3309
N02AX02
ATC
tramadol; systemic, rectal
1.5
10.8
518
3987
RF120, ,
NOMESCO Finland
5.2
10.8
22
43
D06BB04
ATC
podophyllotoxin; topical
2.3
10.8
81
363
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.8
10.7
52
188
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
10.7
538
4179
L04AA29
ATC
[U] tofacitinib
13.0
10.7
18
14
D01AC02
ATC
miconazole; topical
2.1
10.6
100
491
R06AX27
ATC
desloratadine; oral
1.6
10.6
356
2538
J01CF05
ATC
flucloxacillin; systemic
2.2
10.6
86
398
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.7
10.6
33
91
N07BA03
ATC
varenicline; oral
2.3
10.6
78
347
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
10.1
10.5
20
20
L04AC12
ATC
brodalumab; systemic
+∞
10.4
10
*
H02AB04
ATC
methylprednisolone; systemic
1.8
10.4
170
1008
R06AE09
ATC
levocetirizine; oral
1.7
10.1
182
1108
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
10.1
837
7134
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
10.1
289
1984
WZA00
NOMESCO Finland
Concise certificate
2.2
10.1
90
433
C07AB07
ATC
bisoprolol; oral
1.5
10.1
512
3973
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
10.0
142
805
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
10.0
81
375
A10BK01
ATC
dapagliflozin; oral
2.1
9.9
97
484
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
9.9
126
690
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
5.2
9.9
20
39
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.9
9.8
45
158
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.2
9.7
84
399
S02CA02
ATC
flumetasone and antiinfectives; otic
2.4
9.7
69
302
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
9.6
689
5691
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
9.4
877
7591
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.6
9.4
30
84
WQ054, ,
NOMESCO Finland
+∞
9.4
9
*
L43.8
ICD-10 Finland
Other lichen planus
12.4
9.4
16
13
H02AB09
ATC
hydrocortisone; systemic
3.3
9.4
35
109
M10.0
ICD-10 Finland
Idiopathic gout
2.9
9.3
44
157
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
9.3
102
530
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
9.2
318
2271
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
9.2
144
841
A10BK03
ATC
empagliflozin; oral
1.9
9.2
123
684
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
9.2
615
4999
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
9.2
126
707
J01AA02
ATC
doxycycline; systemic
1.5
9.2
946
8329
J01MA12
ATC
levofloxacin; systemic
1.7
9.2
205
1323
3005
Kela drug reimbursment
Tofacitinib
11.6
9.1
16
14
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.7
9.1
183
1150
WQ021, ,
NOMESCO Finland
37.0
9.0
11
*
R60.0
ICD-10 Finland
Localized oedema
1.9
9.0
124
697
RS221, ,
NOMESCO Finland
3.9
9.0
26
68
H01
ICPC
Ear pain/earache
1.8
8.9
130
743
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
8.8
433
3319
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
8.8
63
277
M54.5
ICD-10 Finland
Low back pain
1.5
8.8
432
3311
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
8.8
263
1821
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
8.7
307
2201
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
4.1
8.5
23
57
4AA12, ,
NOMESCO Finland
10.1
8.5
16
16
RF410, ,
NOMESCO Finland
4.2
8.5
22
53
A02BA02
ATC
ranitidine; systemic
1.6
8.5
199
1300
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
8.5
550
4428
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.4
8.4
54
226
S29
ICPC
Skin symptom/complaint other
1.6
8.4
195
1270
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
8.4
126
728
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.7
8.4
44
167
SPAT1255
SPAT
Intravenous administration of medicine
2.1
8.3
80
397
A10AE04
ATC
insulin glargine; parenteral
1.8
8.3
120
685
XQ902
NOMESCO Finland
Other photography
9.5
8.3
16
17
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.6
8.3
27
77
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.5
8.3
344
2548
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.2
8.2
31
97
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
8.2
403
3078
M01AH01
ATC
celecoxib; oral
1.6
8.2
189
1228
A10BB12
ATC
glimepiride; oral
2.2
8.2
67
312
L73.2
ICD-10 Finland
Hidradenitis suppurativa
3.9
8.2
23
59
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.3
8.1
59
261
B03BA03
ATC
hydroxocobalamin; parenteral
2.4
8.1
55
236
N02BE01
ATC
paracetamol; systemic, rectal
1.6
8.1
1095
10021
E0001A1, ,
ATC
3.3
8.1
29
88
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
8.1
281
2005
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.9
8.1
100
543
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
7.9
126
740
162
Kela drug reimbursment
liraglutide
4.0
7.9
22
56
M01AE02
ATC
naproxen; oral, rectal
1.4
7.9
679
5711
RF420, ,
NOMESCO Finland
3.8
7.8
23
61
SPAT1283
SPAT
Restricted health certificate
1.6
7.8
204
1366
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
7.8
469
3713
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.7
431
3364
D01AE15
ATC
terbinafine; topical
2.0
7.7
86
451
M01AB05
ATC
diclofenac; systemic, rectal
1.4
7.7
828
7216
L99
ICPC
Musculoskeletal disease other
3.3
7.7
28
86
A10BX07
ATC
[U] liraglutide
3.8
7.6
23
62
L20.0
ICD-10 Finland
Besnier prurigo
1.9
7.6
90
481
SPAT1153
SPAT
Removal of sutures
1.5
7.6
333
2485
A10BJ02
ATC
liraglutide; parenteral
2.6
7.6
41
158
D07AC04
ATC
fluocinolone acetonide; topical
25.2
7.6
10
*
M01CB03
ATC
auranofin; oral
8.9
7.5
15
17
D07XB02
ATC
triamcinolone; topical
3.8
7.5
22
58
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.1
7.5
71
350
R06.0
ICD-10 Finland
Dyspnoea
1.5
7.5
274
1971
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
7.5
83
434
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.5
7.5
46
189
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.4
449
3548
SCA01
NOMESCO Finland
Preventive oral health care, short
1.5
7.4
324
2415
XX9XT
NOMESCO Finland
Other radiological intervention
80.5
7.4
8
*
ZX120
NOMESCO Finland
Intravenous
1.8
7.4
103
581
A10BX04
ATC
[U] exenatide
4.0
7.4
20
50
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.2
7.3
59
273
R21
ICPC
Throat symptom/complaint
1.5
7.3
229
1595
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.9
7.3
91
495
L60.0
ICD-10 Finland
Ingrowing nail
2.2
7.3
60
280
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
9.4
7.3
14
15
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.5
7.2
45
186
R03AC02
ATC
salbutamol; inhalant
1.4
7.1
639
5376
J01FA01
ATC
erythromycin; systemic
1.6
7.1
159
1024
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.8
7.1
117
694
XQ899
NOMESCO Finland
Other assessment of skin
8.0
7.1
15
19
EC1VA, ,
NOMESCO Finland
2.5
7.1
43
176
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
3.7
7.0
22
61
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
7.0
152
971
J01FA09
ATC
clarithromycin; systemic
1.4
7.0
364
2796
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
4.2
7.0
18
43
RS121, ,
NOMESCO Finland
7.0
7.0
16
23
R05
ICPC
Cough
1.5
7.0
252
1807
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.7
7.0
139
869
Z01.2
ICD-10 Finland
Dental examination
1.4
7.0
525
4291
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.9
7.0
82
438
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.4
7.0
324
2440
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
7.0
68
340
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.8
6.9
33
119
K05.30
ICD-10 Finland
Periodontitis complex
1.6
6.9
167
1096
J01CA04
ATC
amoxicillin; systemic
1.4
6.9
1008
9159
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
8.3
6.8
14
17
SPAT1325
SPAT
Vaccination
1.4
6.8
309
2315
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
6.8
124
757
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
11.0
6.8
12
11
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
9.4
6.8
13
14
D11AH01
ATC
tacrolimus; topical
4.3
6.8
17
40
Z22.30
ICD-10 Finland
Latent tuberculosis
40.3
6.8
8
*
C08CA13
ATC
lercanidipine; oral
1.7
6.8
137
861
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.4
6.7
46
199
SGA01
NOMESCO Finland
Emergency treatment
1.5
6.7
210
1462
N06AB10
ATC
escitalopram; oral
1.5
6.7
246
1772
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.6
6.6
38
151
NF1DA
NOMESCO Finland
X-ray of hips
3.1
6.6
27
89
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.9
6.6
81
439
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
6.6
320
2425
J01DA09
ATC
[U] cefadroxil
1.4
6.6
310
2337
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
6.6
568
4732
H60.1
ICD-10 Finland
Cellulitis of external ear
3.8
6.5
19
50
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
6.5
103
604
UDC00
NOMESCO Finland
Ear microscopy
1.9
6.5
83
456
WX290
NOMESCO Finland
Other blockage of nerve
1.3
6.5
595
4998
L28
ICPC
Limited function/disability (L)
1.6
6.5
150
974
L08.0
ICD-10 Finland
Pyoderma
6.2
6.5
16
26
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.5
343
2640
J01FA06
ATC
roxithromycin; oral
1.4
6.4
447
3596
A10BG03
ATC
pioglitazone; oral
2.7
6.4
33
124
WXQ26
NOMESCO Finland
UVB broad spectrum light therapy
70.2
6.4
7
*
A41.9
ICD-10 Finland
Sepsis, unspecified
2.4
6.4
41
172
SFA30
NOMESCO Finland
Three-surface restoration
1.4
6.4
518
4267
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
6.4
54
256
SPAT1281
SPAT
Other administrative function
1.8
6.3
86
482
B07.9
ICD-10 Finland
Verruca simplex
2.3
6.3
47
211
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
6.3
89
505
H13
ICPC
Plugged feeling ear
1.5
6.3
188
1295
WX723
NOMESCO Finland
CPAP therapy
2.1
6.3
60
298
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
18.1
6.3
9
5
WQ032, ,
NOMESCO Finland
+∞
6.3
6
*
M07
ICD-10 Finland
Psoriatic and enteropathic arthropathies
+∞
6.3
6
*
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.5
6.2
37
150
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
6.2
115
706
H60.3
ICD-10 Finland
Other infective otitis externa
2.7
6.2
32
121
UJF32
NOMESCO Finland
Coloscopy
1.4
6.1
261
1930
SPAT1104
SPAT
Monitoring of emergency patient
2.0
6.1
65
336
N05CF02
ATC
zolpidem; oral
1.5
6.1
199
1396
R02
ICPC
Shortness of breath/dyspnoea
1.7
6.1
122
765
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
6.1
73
394
L57.0
ICD-10 Finland
Actinic keratosis
1.8
6.0
86
490

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1207
4845
19.47
323.31
15.1
6.3
—
—
—
0
0
1213
5127
18.93
300.59
15.2
5.8
0.61
0.58
e9/l
5.32
1192
4463
1213
5134
18.89
299.92
15.2
5.8
0.05
0.04
e9/l
10.16
1192
4467
493
858
8.60
294.88
1.2
1.5
—
—
—
0
0
1216
5298
18.53
287.12
15.3
5.8
2.04
1.99
e9/l
0.38
1199
4725
1214
5321
18.00
283.39
15.5
6.1
0.21
0.19
e9/l
5.05
1193
4700
617
1425
7.28
279.86
1.4
1.3
398.26
489.81
titre
0.56
115
269
1126
4654
10.97
274.53
15.5
6.0
0.79
0.68
%
12.29
1121
4365
1131
4817
10.72
262.87
15.6
5.9
3.13
2.88
%
3.90
1126
4525
1132
4849
10.68
260.68
16.0
6.3
8.95
8.57
%
5.05
1127
4564
1136
5009
10.41
249.28
15.8
6.0
30.14
28.37
%
8.52
1130
4728
1127
4944
10.03
248.13
15.3
5.8
55.68
56.82
%
3.43
1122
4661
1220
5920
15.98
238.41
16.9
9.2
3.89
4.08
e9/l
3.64
1198
5175
397
718
7.49
224.04
5.6
4.6
0.04
0.15
%
1.07
82
205
405
767
7.19
218.20
5.7
4.5
0.03
0.13
%
2.83
93
252
395
738
7.23
215.42
5.2
4.2
0.35
0.61
%
1.90
88
256
412
815
6.91
212.15
5.6
4.4
0.47
1.00
%
3.91
99
301
582
1638
5.59
203.19
1.4
1.6
—
—
—
0
0
505
1329
5.55
188.79
1.4
1.6
—
—
—
0
0
105
26
43.81
175.07
1.6
1.3
9.07
9.79
ug/l
0.36
105
26
597
2087
4.41
150.92
1.5
1.8
—
—
—
0
0
91
35
27.86
132.93
2.0
1.6
—
—
—
0
0
1197
7535
7.66
124.87
7.9
3.8
12.32
10.50
mm/h
4.79
1158
7023
891
4600
3.92
119.69
17.5
9.0
0.00
0.00
e9/l
0.73
858
3781
1217
7903
8.38
118.79
12.6
7.5
78.16
77.01
u/l
0.53
1201
7492
137
187
8.06
96.48
3.1
3.6
3.97
4.34
e9/l
1.00
137
187
194
390
5.66
93.85
1.1
1.2
1.36
1.07
u/ml
—
7
30
137
193
7.81
93.83
3.2
4.0
54.69
56.97
%
1.21
137
193
1036
6861
3.42
75.41
5.6
3.8
—
—
—
0
0
170
370
5.13
74.65
1.3
1.2
—
—
—
0
0
103
138
8.01
73.37
1.1
1.2
—
—
—
0
0
55
32
17.90
67.30
1.4
2.1
7.34
9.87
mg/l
1.21
36
26
815
4937
2.72
65.88
6.4
4.3
0.00
0.00
estimate
0.50
265
934
813
4933
2.70
65.26
4.9
3.1
0.01
0.00
estimate
0.32
271
972
818
4981
2.70
65.14
4.9
3.2
0.00
0.01
estimate
0.80
243
873
496
2612
2.44
50.13
5.4
3.5
0.00
0.01
estimate
1.28
250
898
483
2569
2.39
47.16
12.8
6.7
—
—
—
0
0
293
1242
2.75
46.07
1.6
1.5
—
—
—
0
0
106
250
4.52
41.71
1.5
1.4
—
—
—
0
0
491
2743
2.26
41.66
3.0
2.6
4423.26
5882.42
umol/l
0.35
451
2456
46
47
10.11
40.25
1.2
1.0
1145.41
1567.19
miu/ml
1.77
46
47
343
1670
2.43
39.81
1.3
1.2
6.43
11.17
u/ml
0.79
140
692
58
81
7.45
39.64
1.6
1.4
43.12
33.59
%
0.77
31
57
1262
10730
5.53
39.12
20.1
12.8
15.82
23.54
mg/l
23.11
1121
8362
566
3417
2.15
38.91
4.1
3.5
40.46
73.17
e6/l
1.23
447
2425
488
2823
2.16
37.02
4.5
2.9
—
—
—
0
0
367
1895
2.30
36.85
3.6
2.7
568.46
559.50
mosm/kgh2o
0.32
342
1648
628
4024
2.07
36.08
4.6
3.0
5.69
5.79
ph
0.39
37
402
263
1185
2.52
35.74
2.0
1.7
—
—
—
0
0
100
254
4.18
35.68
1.2
1.2
8.28
2.35
u/ml
—
5
23
101
259
4.14
35.58
1.2
1.2
5.73
9.27
u/ml
0.31
11
43
60
100
6.24
34.75
1.9
1.6
41.53
58.51
%
1.77
32
71
373
2007
2.20
33.41
3.2
2.5
4.56
5.01
e6/l
0.26
355
1820
108
315
3.65
31.68
1.2
1.3
287.14
89.63
titre
—
7
27
479
2929
2.00
29.87
3.5
3.1
42.92
76.79
e6/l
0.70
416
2248
737
5243
1.92
29.05
5.9
6.6
11.79
11.72
umol/l
0.04
703
5003
330
1783
2.14
28.65
1.3
1.3
21.17
29.66
iu/ml
1.26
88
574
66
145
4.74
28.26
1.7
3.9
0.80
1.47
%
1.15
59
137
365
2090
2.03
26.89
1.5
1.4
3.16
2.48
g/l
5.15
243
1360
189
839
2.46
25.99
4.5
3.6
—
—
—
0
0
476
3021
1.90
25.75
4.1
3.9
12.02
8.85
mg/mmol
0.58
319
1983
83
236
3.69
25.23
1.1
1.2
—
—
—
0
0
586
3992
1.85
25.21
2.7
2.2
72.33
74.85
nmol/l
1.34
544
3639
48
88
5.62
25.20
1.5
1.3
18999.78
129010.34
e6/l
0.85
36
65
199
930
2.34
24.32
3.2
2.3
0.22
0.22
g/l
0.33
188
875
427
2656
1.90
24.28
3.6
3.0
0.33
0.45
e6/l
0.76
372
2002
423
2644
1.88
23.56
3.3
2.9
—
—
—
0
0
77
219
3.67
23.39
1.9
1.6
12144.13
14004.77
e6/l
0.13
63
163
530
3605
1.79
22.10
4.1
3.5
40.81
33.10
u/l
2.38
507
3436
443
2864
1.83
21.83
3.3
3.3
530.41
298.44
mg/l
0.40
289
1925
585
4107
1.77
21.79
4.8
5.2
35.45
36.18
g/l
2.33
546
3861
477
3171
1.79
21.31
3.2
3.3
8.28
8.31
mmol/l
0.05
398
2727
262
1440
2.02
21.03
2.2
2.2
—
—
—
0
0
148
649
2.44
20.73
1.4
1.8
1.21
1.32
g/l
0.46
137
606
398
2557
1.80
19.63
4.5
4.4
—
—
—
0
0
68
201
3.51
19.51
5.6
4.0
—
—
—
0
0
1273
11650
4.04
19.50
25.3
9.5
35.17
29.10
u/l
22.17
1268
11308
191
964
2.15
19.14
2.8
2.9
1.79
1.79
%
0.03
178
873
757
5891
1.67
18.00
5.0
5.2
6.94
6.69
mmol/l
2.16
710
5537
361
2336
1.75
16.97
1.3
1.2
2.06
1.66
u/ml
0.18
117
679
163
814
2.14
16.69
2.0
2.6
11.99
10.61
g/l
2.31
148
751
76
265
2.98
16.66
2.1
3.4
—
—
—
0
0
350
2257
1.75
16.60
2.6
2.1
3.31
2.89
mg/l
2.25
307
1938
341
2184
1.76
16.56
5.1
3.1
—
—
—
0
0
56
163
3.54
16.46
1.7
1.5
—
—
—
0
0
100
410
2.56
16.10
4.8
3.0
—
—
—
0
0
1124
9891
1.95
16.02
7.1
5.2
40.99
39.45
mmol/mol
5.62
1058
9320
60
186
3.33
16.01
1.1
1.1
54.60
105.20
iu/ml
0.37
12
49
457
3200
1.66
15.82
2.9
2.7
80.05
59.92
u/l
0.38
423
3006
144
703
2.18
15.59
2.1
3.0
74.72
73.04
e9/l
0.25
120
536
789
6336
1.61
15.44
4.8
3.8
1789.35
1939.78
e6/l
0.04
20
97
128
603
2.24
15.12
1.7
2.6
—
—
—
0
0
360
2410
1.68
14.61
3.1
2.7
—
—
—
0
0
584
4416
1.58
14.37
11.9
12.4
1.16
1.21
inr
1.18
212
1319
924
7786
1.63
14.17
4.8
3.2
75.43
50.28
u/l
6.15
874
7374
49
146
3.45
13.93
1.6
1.4
—
—
—
0
0
229
1366
1.82
13.90
2.4
2.4
2.49
2.34
g/l
3.12
213
1269
40
104
3.94
13.85
2.3
4.2
—
—
—
0
0
1169
10545
1.99
13.73
5.6
3.7
1.56
1.35
mmol/l
11.88
1113
9851
84
344
2.54
13.57
1.1
1.3
188.62
212.42
miu/ml
0.17
25
157
241
1473
1.78
13.46
2.5
2.5
13.11
14.07
umol/l
1.19
229
1375
142
734
2.05
13.20
1.7
2.9
68.30
66.99
g/l
1.08
127
680
392
2740
1.61
13.19
3.7
3.5
—
—
—
0
0
216
1302
1.79
12.59
2.3
2.4
122.54
141.73
ug/g
0.39
181
1060
138
720
2.02
12.49
3.3
4.1
1.22
1.23
mmol/l
0.59
124
632
500
3736
1.55
12.46
3.7
3.3
26.11
43.80
ng/l
2.60
337
2428
1197
10960
2.04
12.35
6.0
4.2
4.64
4.73
mmol/l
2.30
1149
10331
599
4677
1.52
12.05
6.5
7.3
1.21
1.21
mmol/l
0.03
496
4012
94
445
2.20
10.97
1.1
1.1
—
—
—
0
0
206
1272
1.73
10.96
2.5
2.5
22.15
24.47
%
1.29
178
1100
283
1911
1.61
10.67
1.9
1.6
195763146.69
32689247.63
pmol/l
0.82
236
1655
25
56
4.53
10.51
2.6
3.0
47280.00
39666.16
ug/l
1.21
25
56
487
3726
1.49
10.36
2.1
1.9
91.92
95.76
pmol/l
1.15
303
2019
50
184
2.79
10.01
2.9
2.9
1.37
1.53
mmol/l
1.03
50
179
74
331
2.31
9.90
2.1
2.4
102.05
2698.31
u/l
2.41
18
131
309
2166
1.56
9.85
5.8
3.4
1.02
1.02
kg/l
0.13
38
287
52
198
2.69
9.77
1.6
3.9
—
—
—
0
0
109
574
1.98
9.61
1.2
1.2
—
—
—
0
0
1063
9582
1.57
9.33
4.8
4.3
1.81
2.11
mu/l
1.04
991
8887
243
1631
1.60
9.29
2.9
3.7
0.80
0.82
mmol/l
1.03
227
1548
238
1600
1.60
9.02
2.8
2.7
0.84
0.99
e6/l
0.46
161
891
62
268
2.38
8.98
1.6
4.0
49.30
52.77
mg/l
0.05
45
213
62
268
2.38
8.98
1.6
4.0
53.44
71.40
mg/l
0.31
43
213
1133
10403
1.65
8.83
5.1
4.1
6.19
5.93
mmol/l
7.49
1063
9652
1182
10983
1.76
8.71
17.3
14.4
3.98
3.97
mmol/l
0.50
1155
10715
1177
10928
1.74
8.64
17.2
14.4
139.38
139.69
mmol/l
4.56
1153
10679
123
699
1.84
8.62
1.5
1.3
433.31
250.96
u/ml
0.80
114
649
207
1363
1.62
8.52
1.2
1.2
—
—
—
0
0
132
771
1.79
8.46
5.2
3.1
—
—
—
0
0
285
2024
1.52
8.42
1.8
1.5
19.68
20.53
nmol/l
0.35
246
1755
1190
11097
1.77
8.41
5.8
4.5
2.81
2.86
mmol/l
0.89
1121
10396
182
1166
1.65
8.35
1.4
1.3
—
—
—
0
0
1174
10915
1.71
8.28
5.4
4.1
1.32
1.41
mmol/l
12.73
1111
10245
35
118
3.02
8.23
3.1
3.1
—
—
—
0
0
225
1531
1.57
8.04
1.9
1.6
1105.63
1174.88
nmol/l
0.59
178
1195
142
860
1.73
8.03
3.5
3.7
2.54
1.97
mmol/l
0.96
114
705
334
2472
1.47
8.01
3.0
3.0
816.17
1094.47
ng/l
1.54
278
2077
48
195
2.52
7.97
1.1
1.3
—
—
—
0
0
75
371
2.08
7.87
1.9
2.0
2.56
2.01
ug/l
0.12
63
336
56
246
2.33
7.85
1.3
2.4
0.95
0.86
nmol/l
0.40
46
215
892
7863
1.42
7.83
4.0
3.7
14.70
14.66
pmol/l
0.19
817
7237
150
945
1.66
7.33
2.6
2.2
306.30
369.81
nmol/l
4.52
141
888
122
729
1.74
7.24
3.7
3.0
10.59
6.13
e9/l
0.64
97
624
81
428
1.95
7.11
1.5
1.6
—
—
—
0
0
1275
12252
2.40
6.98
35.5
18.4
41.63
41.55
%
0.08
1229
11568
1275
12257
2.39
6.88
35.6
18.3
252.99
249.58
e9/l
1.09
1270
11985
43
180
2.44
6.74
1.3
1.8
—
—
—
0
0
1275
12270
2.35
6.63
35.6
18.2
4.61
4.61
e12/l
0.23
1269
11974
1275
12271
2.35
6.61
35.6
18.3
6.98
6.66
e9/l
7.74
1270
11972
1205
11393
1.70
6.55
18.9
11.7
—
—
—
0
0
45
196
2.34
6.48
1.1
1.1
—
—
—
0
0
524
4319
1.35
6.48
3.0
2.7
137.80
135.95
ug/l
0.07
487
4035
63
316
2.04
6.42
1.4
2.7
12.11
10.22
g/l
1.31
54
290
40
167
2.44
6.32
3.7
3.3
18.25
28.04
u/ml
0.15
40
162
55
264
2.13
6.29
1.7
1.4
—
—
—
0
0
28
101
2.81
5.91
2.6
2.5
—
—
—
0
0
45
205
2.24
5.87
1.2
1.1
—
—
—
0
0
304
2326
1.40
5.87
1.7
1.8
1.29
1.05
mg/l
0.44
233
1739
23
75
3.10
5.78
1.3
1.7
—
—
—
0
0
30
114
2.67
5.76
1.3
1.2
—
—
—
0
0
53
260
2.08
5.76
6.5
3.2
40.02
33.89
umol/l
1.16
45
240
173
1195
1.52
5.71
3.3
3.0
9.72
8.21
umol/l
0.29
154
1053
38
165
2.34
5.55
1.3
1.3
—
—
—
0
0
28
105
2.70
5.52
1.7
2.7
33.00
32.74
pg
0.09
28
105
58
301
1.97
5.42
1.5
1.4
0.25
0.25
g/l
0.11
58
289
99
613
1.67
5.20
3.1
3.4
5.33
5.15
kpa
1.11
92
590
98
607
1.66
5.14
3.1
3.4
7.41
7.41
ph
0.08
15
76
368
2959
1.34
5.11
2.2
2.2
207.19
252.34
u/l
0.45
349
2808
172
1214
1.48
5.11
1.6
1.6
—
—
—
0
0
503
4229
1.31
5.09
5.9
6.7
1.21
1.21
mmol/l
0.03
462
3904
59
316
1.91
5.05
1.5
1.4
1.27
1.21
g/l
0.85
59
302
181
1298
1.46
4.96
4.8
6.6
1.04
1.02
mmol/l
0.39
173
1216
21
72
2.95
4.88
1.2
1.2
—
—
—
0
0
64
357
1.83
4.85
3.6
3.8
0.36
0.26
g/l
0.37
36
164
25
95
2.66
4.83
14.0
8.7
7.96
7.22
mmol/l
0.37
19
80
17
53
3.24
4.62
1.6
1.5
—
—
—
0
0
527
4504
1.28
4.57
3.5
2.6
—
—
—
0
0
26
104
2.53
4.56
2.1
2.8
—
—
—
0
0
98
1478
0.64
4.49
1.3
1.4
—
—
—
0
0
11
19
5.83
4.44
1.4
1.1
—
—
u/ml
—
0
0
201
1512
1.39
4.21
2.8
2.9
2.18
1.56
e6/l
0.62
124
810
34
165
2.09
3.89
2.6
2.3
—
—
—
0
0
51
288
1.80
3.77
1.3
1.4
249.23
287.57
ug/g
0.80
32
161
333
2754
1.28
3.60
3.5
4.2
7.40
7.40
ph
0.02
87
525
39
206
1.92
3.56
3.6
3.6
—
—
—
0
0
33
165
2.03
3.51
1.4
1.2
—
—
—
0
0
65
402
1.65
3.51
1.8
2.2
1.53
1.53
g/l
0.01
52
351
810
7425
1.24
3.43
3.6
3.4
—
—
—
0
0
36
189
1.93
3.36
1.7
2.2
127.54
132.35
g/l
0.72
26
144
30
148
2.05
3.32
1.5
1.3
57.63
63.31
mmol/l
0.34
16
128
61
377
1.65
3.32
1.7
1.7
—
—
—
0
0
9
19
4.76
3.24
1.1
1.0
—
—
—
0
0
9
19
4.76
3.24
1.1
1.0
—
—
—
0
0
9
19
4.76
3.24
1.1
1.0
—
—
—
0
0
29
143
2.05
3.22
2.3
3.1
—
—
—
0
0
12
34
3.55
3.20
1.8
2.2
—
—
—
0
0
35
186
1.91
3.17
2.3
2.5
16.52
16.60
%
0.04
20
97
47
276
1.73
3.10
1.5
2.8
37.05
38.45
g/l
0.66
39
251
457
3979
1.23
3.08
2.0
2.0
—
—
—
0
0
134
994
1.39
3.08
1.6
1.7
—
—
—
0
0
69
449
1.57
3.06
3.5
3.6
—
—
—
0
0
21
93
2.28
3.04
1.7
2.4
0.97
1.31
e9/l
1.42
21
86
338
2852
1.25
3.04
1.9
1.7
1.64
1.45
mmol/l
3.38
284
2449
18
78
2.33
2.75
1.1
1.1
—
—
—
0
0
36
203
1.80
2.75
4.9
4.6
2.04
2.49
mmol/l
0.60
26
140
10
29
3.47
2.69
1.5
2.1
—
—
—
0
0
308
2609
1.24
2.64
5.1
4.0
89.23
92.46
%
1.40
299
2550
30
163
1.86
2.59
2.3
3.4
—
—
—
0
0
17
74
2.31
2.58
1.3
1.2
—
—
—
0
0
19
90
2.13
2.39
1.1
1.3
6.14
6.70
g/l
0.38
13
66
91
668
1.39
2.28
3.5
4.1
76.05
84.08
ng/l
0.38
78
599
5
9
5.57
2.21
1.0
1.0
—
—
—
0
0
16
73
2.21
2.21
1.1
1.0
—
—
—
0
0
35
211
1.68
2.18
4.3
3.4
20.96
23.04
mg/l
0.15
25
129
29
166
1.76
2.16
1.3
1.7
0.64
0.81
g/l
0.56
22
133
11
251
0.43
2.12
1.1
1.2
—
—
—
0
0
35
213
1.66
2.11
2.6
2.1
—
—
—
0
0
8
25
3.21
2.09
1.1
1.3
-0.48
1.44
mmol/l
—
8
25
57
391
1.48
2.07
3.5
3.9
24.19
24.90
mmol/l
1.20
52
371
86
638
1.37
2.04
1.3
1.2
—
—
—
0
0
18
90
2.01
2.01
1.1
1.3
3.08
2.92
g/l
0.18
12
65
18
90
2.01
2.01
1.1
1.3
0.40
0.35
g/l
0.34
13
65
13
57
2.29
1.98
1.3
1.2
—
—
—
0
0
19
98
1.95
1.95
1.3
2.3
—
—
—
0
0
18
91
1.99
1.95
1.2
1.4
—
—
—
0
0
16
78
2.06
1.91
1.2
1.1
—
—
—
0
0
53
366
1.47
1.89
2.1
3.6
—
—
—
0
0
13
59
2.22
1.84
1.0
1.1
155.17
220.32
iu/ml
0.48
13
59
18
95
1.91
1.75
3.7
3.1
136.26
16.30
mg/l
0.54
13
69
40
266
1.52
1.72
2.3
2.3
445.85
90.75
ug/min
1.00
19
172
103
809
1.30
1.70
1.2
1.2
—
—
—
0
0
14
68
2.07
1.70
1.1
1.0
—
—
—
0
0
16
83
1.94
1.65
1.1
1.2
0.02
0.72
u/ml
—
5
43
29
182
1.61
1.61
1.3
1.2
—
—
—
0
0
16
84
1.92
1.60
1.1
1.1
—
—
—
0
0
76
580
1.33
1.56
3.6
2.3
—
—
—
0
0
512
4714
1.14
1.55
2.6
2.6
—
—
—
0
0
69
901
0.75
1.51
1.5
1.4
—
—
—
0
0
43
300
1.45
1.50
1.1
1.1
—
—
—
0
0
9
37
2.44
1.48
1.0
1.0
—
—
—
0
0
215
2469
0.85
1.47
2.2
2.8
0.54
0.71
ug/l
5.86
126
1465
10
45
2.23
1.46
2.1
3.5
—
—
—
0
0
16
87
1.85
1.46
1.2
1.1
350.70
407.94
nmol/l
—
10
79
7
28
2.51
1.45
1.1
1.1
—
—
—
0
0
5
16
3.13
1.44
1.4
1.1
—
—
—
0
0
15
81
1.86
1.40
1.5
2.5
935.88
644.54
ml
—
8
54
58
433
1.36
1.40
2.5
2.2
—
—
—
0
0
17
97
1.76
1.35
1.4
1.2
—
—
—
0
0
86
685
1.27
1.33
1.1
1.2
75.60
163.88
iu/ml
3.14
28
288
23
356
0.64
1.33
1.5
1.6
—
—
—
0
0
6
24
2.51
1.30
1.0
2.2
—
—
—
0
0
21
129
1.64
1.30
1.0
1.4
—
—
—
0
0
60
457
1.33
1.29
4.1
3.9
24.32
24.21
mmol/l
0.08
60
447
17
99
1.73
1.27
1.1
1.1
—
—
—
0
0
8
35
2.29
1.27
2.4
2.4
—
—
—
0
0
88
708
1.26
1.26
1.4
1.4
—
—
—
0
0
47
346
1.37
1.26
2.2
2.2
314.40
430.58
ug/l
0.35
42
327
108
893
1.23
1.22
5.0
4.5
—
—
—
0
0
5
19
2.64
1.21
2.0
1.8
—
—
—
0
0
5
20
2.51
1.15
1.2
1.1
—
—
—
0
0
52
397
1.32
1.13
1.3
1.2
—
—
—
0
0
7
30
2.34
1.12
1.4
2.0
—
—
—
0
0
11
58
1.90
1.12
1.4
1.3
153.78
144.41
nmol/l
0.14
11
58
5
21
2.39
1.09
1.0
1.1
—
—
—
0
0
21
136
1.55
1.09
1.0
1.4
0.61
0.62
nmol/l
0.05
21
129
10
52
1.93
1.06
2.5
3.2
—
—
—
0
0
19
121
1.58
1.05
1.1
1.4
—
—
nmol/l
—
0
0
144
1658
0.85
1.04
2.6
3.0
2.47
2.44
mmol/l
1.66
133
1477
5
22
2.28
1.03
1.4
1.5
—
—
—
0
0
13
75
1.74
1.03
1.6
2.0
2.14
1.95
u/field
—
7
41
97
813
1.21
1.00
9.2
10.1
—
—
—
0
0
64
514
1.26
0.98
1.5
2.6
—
—
—
0
0
337
3103
1.12
0.97
2.5
2.4
—
—
—
0
0
55
436
1.27
0.94
1.5
2.5
—
—
—
0
0
13
78
1.67
0.91
1.2
1.2
—
—
—
0
0
33
245
1.36
0.89
1.2
1.6
—
—
—
0
0
13
79
1.65
0.88
1.3
1.4
31804.29
39077.77
e6/l
—
7
43
13
79
1.65
0.88
1.1
1.1
—
—
—
0
0
12
193
0.62
0.88
1.7
1.2
—
—
—
0
0
67
551
1.23
0.85
1.5
2.5
—
—
—
0
0
18
120
1.51
0.85
1.4
1.7
—
—
—
0
0
8
140
0.57
0.83
1.3
1.4
228.88
235.83
pmol/l
—
8
140
96
821
1.18
0.82
2.3
2.3
5.25
7.68
ug/l
1.57
78
742
11
177
0.62
0.81
1.5
1.4
—
—
—
0
0
11
176
0.62
0.80
1.5
1.4
—
—
—
0
0
67
556
1.22
0.80
1.4
2.4
—
—
—
0
0
67
558
1.21
0.77
1.5
2.4
—
—
—
0
0
12
184
0.65
0.74
1.4
1.5
—
—
—
0
0
9
55
1.64
0.73
1.0
1.2
—
—
—
0
0
65
544
1.21
0.73
1.5
2.3
—
—
—
0
0
7
40
1.75
0.71
5.9
2.7
—
—
—
0
0
9
57
1.58
0.71
1.0
1.1
—
12.50
—
0
6
70
593
1.19
0.69
2.1
3.3
4.37
4.60
pmol/l
1.32
60
533
57
681
0.83
0.68
2.3
2.8
113.08
168.73
ng/l
1.34
49
614
13
86
1.52
0.66
1.1
1.3
—
—
—
0
0
31
242
1.29
0.64
1.5
3.6
—
—
—
0
0
338
3178
1.09
0.64
2.6
3.4
2.34
2.35
mmol/l
0.56
305
2879
57
479
1.20
0.63
1.2
1.4
25.84
26.85
iu/l
0.09
49
407
44
361
1.23
0.62
2.3
2.6
—
—
—
0
0
5
30
1.67
0.61
5.0
3.1
—
—
—
0
0
137
1235
1.12
0.61
1.5
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
2.7
—
—
—
0
0
8
52
1.54
0.59
1.1
1.9
—
—
—
0
0
8
53
1.51
0.58
1.5
1.2
—
—
—
0
0
8
53
1.51
0.58
1.5
1.3
157.50
177.67
mmol/24h
—
8
53
8
54
1.48
0.57
1.7
2.0
183.75
129.13
nmol/l
—
8
47
29
229
1.27
0.57
1.7
1.6
102.78
123.01
u/ml
—
10
43
23
176
1.31
0.56
1.4
1.3
14.76
49.38
u/l
1.76
23
152
14
195
0.71
0.56
1.1
1.1
0.15
2.35
u/ml
—
6
97
20
150
1.34
0.56
1.1
1.5
0.24
0.32
nmol/l
0.38
14
123
27
339
0.79
0.54
8.3
9.1
—
—
—
0
0
6
38
1.58
0.54
1.2
1.4
—
—
—
0
0
20
151
1.33
0.54
1.2
1.7
—
—
—
0
0
9
63
1.43
0.52
1.2
1.5
—
—
—
0
0
6
40
1.50
0.51
1.7
1.4
5.60
6.36
mmol/l
—
6
40
58
669
0.86
0.50
1.5
1.7
—
—
—
0
0
44
371
1.19
0.50
1.3
1.4
9.95
7.75
u/l
0.43
37
306
30
244
1.23
0.48
1.2
1.2
289.50
260.68
u/ml
0.26
24
151
14
102
1.38
0.47
1.9
2.4
7.51
6.45
umol/l
—
9
68
10
68
1.47
0.47
1.7
2.6
0.26
0.22
e9/l
—
10
62
13
94
1.39
0.46
1.5
2.1
—
—
—
0
0
13
95
1.37
0.43
1.9
2.6
—
—
—
0
0
23
184
1.25
0.43
1.1
1.1
—
8.35
—
0
15
11
78
1.41
0.43
1.5
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
11
79
1.40
0.40
1.2
1.4
1.49
1.53
g/l
0.20
11
79
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
45
390
1.16
0.40
4.9
5.0
—
—
—
0
0
137
1271
1.09
0.39
1.5
1.4
—
—
—
0
0
10
71
1.41
0.39
1.7
2.5
327.60
614.97
e6/l
—
10
63
18
226
0.79
0.39
1.1
1.1
0.67
2.47
u/ml
—
8
119
120
1107
1.09
0.39
8.6
9.6
0.79
1.13
mmol/l
0.41
96
905
0
19
0.00
0.39
0.0
2.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
36.21
—
0
11
13
170
0.76
0.38
1.5
1.2
3.00
4.94
u/ml
—
6
71
5
36
1.39
0.38
1.0
1.6
—
—
—
0
0
45
392
1.15
0.38
1.9
1.9
190.18
218.11
pmol/l
1.46
38
375
9
68
1.33
0.37
1.6
1.3
—
—
—
0
0
8
115
0.69
0.37
1.4
1.7
—
—
—
0
0
12
90
1.34
0.36
1.2
1.1
—
—
—
0
0
6
42
1.43
0.35
1.8
2.9
—
—
—
0
0
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
6
46
1.31
0.33
1.2
1.2
—
—
—
0
0
90
828
1.09
0.32
1.4
1.4
—
—
—
0
0
6
47
1.28
0.32
1.2
2.6
13.20
20.08
ug/l
—
6
41
6
47
1.28
0.32
1.0
1.0
—
—
—
0
0
427
4142
1.05
0.31
3.5
4.2
1.43
2.09
ug/l
4.85
382
3781
7
52
1.35
0.31
1.0
1.6
—
—
—
0
0
13
164
0.79
0.30
1.1
1.1
0.70
4.33
u/ml
—
6
68
7
54
1.30
0.30
1.1
1.6
—
—
—
0
0
12
93
1.29
0.30
1.2
1.6
1.13
1.01
g/l
0.49
12
93
7
57
1.23
0.29
3.3
3.1
786.00
1160.98
u/ml
—
7
57
14
173
0.81
0.28
1.1
1.0
11.00
2.30
u/ml
—
7
84
20
237
0.84
0.28
1.5
1.4
56.87
24.82
e6/l
0.25
15
185
309
2987
1.05
0.27
1.4
1.4
—
—
—
0
0
46
415
1.11
0.26
1.4
1.5
246.00
275.08
mu/l
0.53
38
380
20
235
0.85
0.26
1.1
1.1
—
—
—
0
0
9
72
1.25
0.25
1.4
1.7
4.89
6.63
u/l
—
9
56
14
114
1.23
0.25
1.2
1.6
—
—
—
0
0
105
987
1.07
0.25
3.1
2.6
35.78
87.98
u/l
0.56
100
862
20
234
0.85
0.25
1.1
1.1
—
—
—
0
0
34
304
1.12
0.23
1.1
1.1
—
—
—
0
0
10
79
1.27
0.22
1.3
1.3
—
—
—
0
0
68
633
1.08
0.21
6.1
6.2
—
—
—
0
0
5
42
1.19
0.21
1.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
13
156
0.83
0.21
2.2
2.2
—
1088.00
—
0
10
0
12
0.00
0.21
0.0
7.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
13.00
—
0
5
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
15
126
1.19
0.21
1.1
1.1
—
—
—
0
0
11
89
1.24
0.21
2.1
3.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
97
918
1.06
0.20
3.6
4.6
54.11
16.38
ug/l
0.36
79
752
9
112
0.80
0.20
1.2
1.3
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
50
540
0.92
0.19
12.6
13.0
—
—
—
0
0
10
81
1.24
0.18
1.1
1.3
2.03
1.94
mmol/l
—
10
75
17
196
0.87
0.18
1.1
1.1
0.16
1.66
u/ml
—
9
82
13
109
1.19
0.18
1.2
1.5
278.57
284.48
mosm/kgh2o
—
7
89
5
68
0.73
0.17
2.0
1.5
—
—
—
0
0
8
68
1.18
0.16
2.3
3.9
—
—
—
0
0
13
111
1.17
0.15
1.5
1.7
—
—
—
0
0
64
604
1.06
0.15
1.0
1.1
—
—
—
0
0
20
178
1.13
0.15
1.3
1.2
—
—
—
0
0
9
83
1.08
0.14
1.1
1.4
71.11
79.81
umol/l
—
9
83
182
1873
0.97
0.14
3.6
3.6
664.49
614.76
ng/l
0.06
118
1390
30
320
0.94
0.09
1.1
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
12
133
0.90
0.07
1.2
1.4
—
—
—
0
0
12
133
0.90
0.07
1.4
1.3
—
—
—
0
0
17
184
0.92
0.07
1.5
1.4
120.71
159.19
pmol/l
0.24
17
179
7
82
0.85
0.07
2.1
2.1
13.73
11.38
%
—
7
82
9
105
0.86
0.06
6.1
16.2
773.78
831.00
nmol/l
—
9
100
13
141
0.92
0.05
2.7
2.6
—
—
—
0
0
38
368
1.03
0.04
3.8
3.8
94.13
3728.66
u/ml
0.76
32
321
130
1284
1.01
0.03
1.4
1.2
—
—
—
0
0
117
1183
0.99
0.02
2.2
2.3
13.75
13.61
nmol/l
0.07
109
1086
22
212
1.04
0.02
2.4
2.7
—
—
—
0
0
20
207
0.97
0.01
1.1
1.1
1.28
6.50
u/ml
2.91
13
105
242
2411
1.00
0.01
2.6
2.4
—
—
—
0
0
22
218
1.01
0.00
1.3
1.5
—
—
—
0
0
26
259
1.00
0.00
1.7
1.9
2.54
4.90
iu/l
—
9
92
19
187
1.02
0.00
1.0
1.1
2.50
2.31
u/ml
—
10
92
5
50
1.00
0.00
4.8
5.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.14
—
0
5
7
69
1.01
-0.00
1.7
1.6
—
—
—
0
0
6
69
0.87
-0.00
2.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.07
—
0
6
0
8
0.00
-0.00
0.0
1.5
—
397.25
—
0
8
0
8
0.00
-0.00
0.0
5.1
—
407.62
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
18.30
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
55
0.91
-0.00
2.0
1.7
—
21.15
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint PSORI_STRICT and mortality.

Females

Parameter HR [95% CI] p-value
PSORI_STRICT 1.781 [1.33, 2.39] < 0.001
Birth year 0.994 [0.99, 1.0] 0.162

During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 1071 females with PSORI_STRICT died.

Males

Parameter HR [95% CI] p-value
PSORI_STRICT 1.697 [1.39, 2.07] < 0.001
Birth year 0.99 [0.98, 1.0] 0.047

During the follow-up period (1.1.1998 — 31.12.2019), 192 out of 2080 males with PSORI_STRICT died.

Mortality risk

Mortality risk for people of age

years, who have PSORI_STRICT.

N-year risk Females Males
1 0.142% 0.38%
5 1.044% 2.072%
10 2.618% 5.097%
15 5.037% 10.192%
20 8.678% 17.05%

Relationships between endpoints

Index endpoint: PSORI_STRICT – Psoriasis (vulgaris), strict definition

GWS hits: 9

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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