Melanoma in situ of trunk

CD2_INSITU_MELANOMA_TRUNK

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D03.5&
  • Cause of death: ICD-10 D03.5&

2 out of 7 registries used, show all original rules.

619

4. Check minimum number of events

None

619

5. Include endpoints

None

619

6. Filter based on genotype QC (FinnGen only)

561

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D03
Name in latin
Melanoma in situ trunci

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 561 220 341
Unadjusted period prevalence (%) 0.13 0.08 0.16
Median age at first event (years) 69.43 65.75 71.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
581
Matched controls
5810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
78.6
307.7
442
226
D03.5
ICD-10 Finland
Melanoma in situ of trunk
+∞
307.7
581
*
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
26.5
291.8
231
141
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
80.2
224.5
121
19
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
342.0
156.8
152
6
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
15.3
144.4
140
118
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.1
135.8
215
354
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
9.1
118.7
175
262
L57.0
ICD-10 Finland
Actinic keratosis
6.0
87.6
208
497
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.1
81.6
275
877
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
41.1
80.0
49
13
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
10.0
78.8
98
116
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
21.8
77.4
59
30
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
48.7
76.6
45
10
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
11.6
74.9
82
81
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
12.5
73.4
76
69
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.6
70.4
166
387
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
26.1
68.0
48
20
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
22.0
57.1
43
21
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
13.1
54.7
54
45
TQW99
NOMESCO Finland
Other minor procedure on skin
5.9
48.8
97
190
S18
ICPC
Laceration/cut
3.8
47.4
418
2348
S77
ICPC
Malignant neoplasm of skin
14.4
46.4
43
32
ZXC50
NOMESCO Finland
Cryotherapy
7.5
43.7
66
97
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
85.2
42.6
47
6
S82
ICPC
Naevus/mole
3.9
42.1
154
490
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.5
41.3
115
299
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
15.9
41.1
36
24
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
14.3
37.7
35
26
C43
ICD-10 Finland
Malignant melanoma of skin
107.2
37.2
40
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.5
37.2
64
108
C43.5
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of trunk
51.4
36.2
43
9
ZZR00
NOMESCO Finland
Flap of skin
8.5
35.9
48
61
TQW40, ,
SPAT
3.9
35.6
124
378
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
8.7
35.1
46
57
PJA12
NOMESCO Finland
Sentinel node biopsy
4.5
33.5
90
226
L82
ICD-10 Finland
Seborrhoeic keratosis
3.1
32.2
185
768
D22
ICD-10 Finland
Melanocytic naevi
5.9
31.9
61
114
8720/2-C44.5
ICD-O-3
Melanoma in situ of skin of trunk
+∞
31.5
30
*
C43.51
ICD-10 Finland
Malignant melanoma of the trunk originating in lentigo maligna
87.4
30.1
33
*
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
10.3
29.7
34
35
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
6.3
28.4
50
86
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
42.2
26.1
32
8
D06BB10
ATC
imiquimod; topical
4.4
25.6
70
177
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.6
24.4
91
287
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
7.8
24.0
34
46
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
42.0
22.9
28
7
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
5.6
22.4
44
84
SPAT1153
SPAT
Removal of sutures
2.4
22.1
257
1462
XQ845
NOMESCO Finland
Dermatoscopy
6.7
22.1
36
57
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
7.7
21.8
31
42
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
7.1
21.4
33
49
XQ848
NOMESCO Finland
Dermatological photography
5.0
19.5
43
91
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
5.7
19.1
36
66
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
24.7
18.8
26
11
8743/3-C44.5
ICD-O-3
Low cumulative sun damage melanoma of skin of trunk
+∞
17.8
17
*
S29
ICPC
Skin symptom/complaint other
2.3
16.2
160
830
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
5.9
16.0
29
51
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
17.8
15.7
24
14
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
5.4
15.5
31
60
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
29.5
15.3
20
7
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
11.3
14.6
27
25
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
37.1
14.5
18
5
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
5.0
13.9
30
62
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
51.2
12.9
15
*
ZXC20
NOMESCO Finland
Use of chemical agents
4.7
12.5
29
64
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
12.0
12.4
22
19
QBE10, ,
SPAT
18.5
12.1
18
10
Z2221
NOMESCO Finland
Medical doctor
2.0
11.9
177
1057
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
35.8
11.3
14
*
C44.52
ICD-10 Finland
Spinocellular carcinoma of the skin on the torso
13.0
11.2
19
15
S54
ICPC
Skin, Repair/fix-suture/cast/prosth device
3.9
11.2
33
88
A98
ICPC
Health maint/preventive medicine
5.7
11.2
568
5138
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
44.2
11.0
13
*
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
18.2
10.8
16
9
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
3.6
10.6
35
101
8742/2-C44.5
ICD-O-3
Lentigo maligna of skin of trunk
+∞
10.4
10
*
ZQZ00
NOMESCO Finland
Treatment of several skin areas
12.3
10.4
18
15
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
4.5
10.4
25
57
C43.53
ICD-10 Finland
Malignant melanoma of the torso nodular
19.2
10.3
15
8
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
3.5
9.7
34
102
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.7
9.6
53
208
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
30.6
9.4
12
*
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
9.7
9.3
18
19
ZXE00
NOMESCO Finland
One hour or less
1.7
9.2
235
1635
S21
ICPC
Skin texture symptom/complaint
2.0
8.9
107
586
N02BE01
ATC
paracetamol; systemic, rectal
2.5
8.7
533
4749
C44.22
ICD-10 Finland
Spinocellular carcinoma of the skin of the outer ear and the outer ear canal
16.6
8.6
13
8
8742/3-C44.9
ICD-O-3
Lentigo maligna melanoma of skin, NOS
91.3
8.4
9
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.4
222
1548
J01DB01
ATC
cefalexin; oral
1.9
8.4
475
4072
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
+∞
8.4
8
*
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
14.7
8.2
13
9
S52
ICPC
Skin, Exc/remov/biopsy/destruc/debrid/caut
14.7
8.2
13
9
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
11.9
8.1
14
12
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
22.4
8.0
11
5
F16
ICPC
Eyelid symptom/complaint
2.9
7.6
36
130
E0000UV, ,
ATC
1.6
7.6
238
1724
TQW80
NOMESCO Finland
Local dermatologic skincare
3.6
7.3
24
69
C43.9
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of skin, unspecified
30.4
7.2
9
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
7.1
398
3305
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
8.9
7.1
14
16
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.4
7.0
25
76
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
4.5
7.0
17
39
XKD00
NOMESCO Finland
Uroflowmetry
1.7
6.9
134
852
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
11.2
6.3
11
10
180
Kela drug reimbursment
Interferon alfa
11.2
6.3
11
10
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
11.2
6.3
11
10
C44.42
ICD-10 Finland
Spinocellular carcinoma of the skin of the scalp and neck
9.4
6.3
12
13
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.2
6.3
53
253
ZXC15
NOMESCO Finland
Use of photodynamic technique
3.9
6.3
18
47
L72.1
ICD-10 Finland
Trichilemmal cyst
2.3
6.3
48
220
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
18.2
6.3
9
5
C43.82
ICD-10 Finland
Overall malignant melanoma of the skin: 'superficial spreading' type
+∞
6.3
6
*
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
3.3
6.2
23
72
Z31.5
ICD-10 Finland
Genetic counselling
2.9
6.1
29
105
D06BX02
ATC
ingenol mebutate; topical
4.2
6.1
16
39
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
6.0
157
1076

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
333
738
9.23
164.48
2.3
1.3
—
—
—
0
0
488
2088
9.35
111.10
4.7
2.3
—
—
—
0
0
170
510
4.30
51.42
1.5
1.4
—
—
—
0
0
100
233
4.98
41.12
1.5
1.3
—
—
—
0
0
572
5265
6.58
13.26
33.0
28.8
133.96
134.55
g/l
0.42
566
5210
572
5264
6.59
13.25
32.5
28.5
91.77
91.67
fl
0.20
566
5211
572
5264
6.59
13.25
33.2
29.2
40.20
40.14
%
0.11
566
5208
572
5264
6.59
13.25
32.5
28.5
30.45
30.49
pg
0.19
566
5210
572
5264
6.59
13.25
32.6
28.6
4.45
4.45
e12/l
0.04
560
5148
572
5264
6.59
13.25
32.7
28.6
6.72
6.89
e9/l
1.11
560
5150
572
5263
6.60
13.24
32.7
28.6
239.89
240.04
e9/l
0.02
561
5167
552
4910
3.49
10.93
20.8
18.8
23.46
26.45
mg/l
1.38
467
4160
567
5149
5.20
10.49
16.5
13.3
26.10
25.61
u/l
0.25
552
5009
260
1858
1.72
9.22
7.6
5.9
—
—
—
0
0
218
1509
1.71
8.51
3.9
3.4
0.75
0.79
ug/l
0.28
154
1040
475
4075
1.91
8.30
11.4
8.9
78.51
81.06
u/l
0.42
451
3875
547
4955
2.78
8.24
6.9
6.3
2.54
2.57
mmol/l
0.32
492
4561
255
1862
1.66
8.01
2.8
2.6
—
—
—
0
0
515
4559
2.14
7.99
6.2
5.2
1.94
1.99
mu/l
0.30
466
4168
305
2333
1.65
7.96
15.6
12.5
0.00
0.00
e9/l
0.81
239
1932
536
4834
2.40
7.72
6.1
5.4
1.44
1.42
mmol/l
0.34
477
4436
538
4865
2.43
7.61
6.1
5.5
4.44
4.45
mmol/l
0.09
482
4506
555
5093
3.01
7.60
25.6
23.0
139.88
139.65
mmol/l
1.36
546
5006
555
5100
2.97
7.44
26.1
23.2
3.97
4.01
mmol/l
2.69
546
5009
528
4752
2.22
7.31
7.7
7.2
39.40
40.16
mmol/mol
1.43
480
4445
547
5001
2.60
7.22
17.9
17.0
—
—
—
0
0
320
2523
1.60
7.04
8.5
6.4
0.68
0.65
%
0.52
293
2363
260
1963
1.59
6.81
5.0
3.7
2.35
2.35
mmol/l
0.05
229
1780
319
2529
1.58
6.74
8.5
6.4
9.21
9.08
%
0.40
295
2370
319
2529
1.58
6.74
8.4
6.3
2.80
2.89
%
0.29
294
2372
515
4649
1.95
6.19
5.2
4.6
1.28
1.29
mmol/l
0.05
457
4241
314
2521
1.53
5.98
8.1
6.3
58.69
58.29
%
0.25
293
2409
365
3029
1.55
5.97
12.0
10.1
3.98
4.26
e9/l
1.34
302
2661
195
1420
1.56
5.74
4.6
4.4
85.44
86.09
%
0.14
190
1405
316
2563
1.51
5.59
8.4
6.4
26.45
26.21
%
0.16
296
2430
341
2815
1.51
5.51
8.1
6.4
0.19
0.20
e9/l
0.51
282
2458
527
4831
1.98
5.50
6.4
5.7
6.04
6.08
mmol/l
0.23
462
4418
332
2734
1.50
5.37
8.0
6.2
0.60
0.61
e9/l
0.37
271
2338
335
2773
1.49
5.21
8.0
6.3
1.75
1.91
e9/l
1.55
277
2446
186
1365
1.53
5.20
3.2
2.8
3.29
4.64
e6/l
1.99
163
1245
332
2745
1.49
5.19
8.1
6.2
0.04
0.04
e9/l
0.13
271
2355
109
705
1.67
5.17
1.5
1.5
—
—
—
0
0
345
2884
1.48
5.03
7.0
7.8
1.21
1.21
mmol/l
0.70
283
2498
307
2508
1.48
5.03
7.2
6.1
6.83
2.77
ug/l
0.64
265
2238
269
2142
1.48
5.02
5.2
4.2
84.82
88.61
e6/l
0.04
201
1552
247
1939
1.48
4.93
4.3
3.6
25.77
103.67
e6/l
1.55
195
1499
286
2319
1.46
4.79
2.6
2.5
81.68
77.96
nmol/l
1.55
251
2072
16
47
3.47
4.78
1.6
1.7
21.73
51.98
ng/l
0.63
16
47
427
3762
1.51
4.54
4.9
4.2
15.23
14.95
pmol/l
1.50
378
3406
404
3521
1.48
4.52
5.0
5.0
4550.30
1194.32
e6/l
—
10
59
312
2590
1.44
4.51
2.5
2.2
94.22
95.34
pmol/l
0.16
176
1397
74
451
1.73
4.35
4.6
4.3
1.23
1.22
mmol/l
0.30
56
395
185
1403
1.47
4.27
2.8
2.6
—
—
—
0
0
215
1680
1.44
4.24
4.2
3.4
0.61
0.48
e6/l
0.24
164
1246
350
2988
1.43
4.22
9.2
7.1
11.36
12.32
umol/l
1.27
330
2873
164
1218
1.48
4.20
4.4
3.1
2.46
2.45
mmol/l
0.26
149
1099
49
266
1.92
4.19
1.3
1.2
77.40
150.78
u/ml
1.30
15
105
221
1744
1.43
4.10
3.7
3.5
—
—
—
0
0
85
548
1.65
4.06
3.6
3.2
65.70
66.32
g/l
0.28
78
508
311
2618
1.40
3.95
6.6
7.0
1.21
1.21
mmol/l
0.82
278
2415
332
2832
1.40
3.87
19.1
16.9
1.30
1.30
inr
0.04
276
2373
69
428
1.69
3.82
4.3
3.8
—
—
—
0
0
199
1562
1.42
3.74
4.1
3.4
—
0.00
estimate
—
0
8
407
3611
1.42
3.69
4.7
4.8
—
2.23
—
0
7
445
4014
1.46
3.68
29.0
23.4
13.88
13.80
%
0.60
440
3980
154
1159
1.45
3.63
3.5
3.1
594.28
543.86
mosm/kgh2o
2.13
130
1015
305
2586
1.38
3.57
6.5
5.4
35.44
35.21
g/l
0.34
288
2434
195
1540
1.40
3.49
2.5
2.3
2.71
2.99
mg/l
0.72
161
1338
190
1494
1.40
3.49
3.2
3.1
334.14
357.40
umol/l
2.27
169
1298
23
100
2.35
3.47
1.3
1.4
—
—
—
0
0
199
1581
1.39
3.43
7.3
6.8
—
—
—
0
0
31
155
2.06
3.36
2.7
3.3
1.62
1.83
index
0.09
13
99
301
2564
1.36
3.34
3.3
2.9
—
—
estimate
—
0
0
222
1808
1.37
3.26
2.3
2.2
170.02
251.27
u/l
1.01
207
1712
214
1737
1.37
3.19
4.7
4.5
7.40
7.40
ph
0.25
139
1251
91
633
1.52
3.15
1.5
1.3
—
—
—
0
0
247
2058
1.35
3.09
3.8
4.1
—
0.73
—
0
11
371
3297
1.35
2.95
3.3
3.5
39.68
55.89
u/l
7.07
343
3100
130
985
1.41
2.90
4.0
3.3
1.47
1.65
e6/l
0.12
75
507
220
1828
1.33
2.72
1.8
1.8
21.72
19.75
nmol/l
1.07
166
1539
253
2155
1.31
2.59
2.1
2.0
1.28
1.31
mmol/l
0.28
185
1770
406
3693
1.33
2.54
5.0
4.7
—
7770.85
—
0
13
91
663
1.44
2.51
4.5
4.6
3.90
29.25
ug/l
1.36
77
557
114
865
1.40
2.51
1.8
2.1
—
—
—
0
0
276
2387
1.30
2.50
3.3
3.1
135.11
156.38
ug/l
0.95
250
2209
23
116
2.02
2.49
1.5
1.8
3.93
4.85
iu/l
—
6
43
9
223
0.39
2.48
1.7
3.6
2.46
1.41
mmol/l
—
9
218
84
606
1.45
2.45
1.5
1.6
—
—
—
0
0
23
117
2.01
2.44
1.3
1.2
8.34
9.21
u/l
0.16
18
93
368
3322
1.29
2.32
5.6
5.5
6.65
6.82
mmol/l
1.04
356
3175
132
1039
1.35
2.31
1.7
1.7
1091.99
1172.12
nmol/l
0.45
88
799
99
745
1.40
2.29
1.4
1.2
—
—
—
0
0
38
233
1.68
2.26
1.9
2.8
10.76
10.68
g/l
0.03
33
208
10
35
2.89
2.21
1.0
1.1
0.18
1.46
u/ml
—
5
16
22
116
1.93
2.13
1.3
1.5
—
—
—
0
0
13
55
2.39
2.13
1.1
1.2
—
—
—
0
0
21
109
1.96
2.13
1.4
1.4
—
—
—
0
0
15
301
0.49
2.10
5.1
3.7
24.37
25.23
mmol/l
1.06
15
292
12
50
2.43
2.03
2.9
2.3
—
—
—
0
0
10
38
2.66
2.01
2.2
2.6
13.60
35.78
mg/l
—
5
27
63
450
1.45
1.96
3.7
2.7
—
—
—
0
0
36
227
1.62
1.95
5.5
4.2
83.57
81.44
mg/l
0.01
30
194
36
227
1.62
1.95
5.4
4.2
25.33
53.19
mg/l
1.52
30
197
96
1222
0.74
1.92
3.8
4.5
1.02
1.02
kg/l
3.33
69
830
49
337
1.50
1.84
1.2
1.5
—
—
—
0
0
5
12
4.19
1.82
2.4
1.5
37.00
35.67
%
—
5
12
168
1414
1.26
1.77
1.5
1.4
—
—
—
0
0
130
1060
1.29
1.77
3.8
3.1
0.90
0.95
e6/l
0.06
77
583
70
521
1.39
1.75
5.1
2.0
459.73
384.05
nmol/l
0.65
62
493
9
36
2.52
1.74
2.1
1.9
30.54
36.01
%
—
9
36
17
89
1.94
1.71
1.5
1.3
2815.56
1694.48
e6/l
—
9
54
71
533
1.38
1.69
2.5
2.3
12.88
13.31
nmol/l
0.16
62
470
72
545
1.37
1.63
4.0
4.6
7.36
7.36
ph
0.06
47
396
8
173
0.45
1.60
5.0
3.5
1.15
1.62
mmol/l
—
8
168
85
663
1.33
1.59
1.7
1.7
—
—
—
0
0
99
792
1.30
1.55
4.0
2.5
1.82
1.79
%
0.09
88
718
15
78
1.95
1.55
1.5
1.4
125066.67
25397.27
e6/l
—
6
40
32
209
1.56
1.55
5.5
3.9
5.74
3.13
ratio
0.25
16
114
122
1004
1.27
1.54
3.2
3.3
0.82
0.82
mmol/l
0.04
112
953
26
162
1.63
1.52
1.5
1.7
8201.08
12289.38
e6/l
0.46
13
120
6
21
2.88
1.51
1.8
2.5
0.62
0.62
mmol/l
—
6
21
69
527
1.35
1.49
1.5
1.6
—
—
—
0
0
10
45
2.24
1.47
1.0
1.0
0.10
0.58
u/ml
—
5
23
15
80
1.90
1.46
1.7
1.7
—
—
—
0
0
26
164
1.61
1.46
1.5
1.5
294.65
280.04
ug/g
0.12
17
106
54
399
1.39
1.43
9.4
10.0
24.26
24.34
mmol/l
0.09
54
392
26
396
0.64
1.42
3.0
4.4
—
—
—
0
0
14
74
1.91
1.40
1.5
1.4
—
—
—
0
0
11
53
2.10
1.39
2.0
3.1
17.50
12.42
index
—
6
36
121
1011
1.25
1.35
1.9
1.5
2.18
2.73
g/l
2.91
74
599
10
47
2.15
1.34
1.1
1.1
—
—
—
0
0
17
98
1.76
1.32
3.6
1.9
32.71
32.60
pg
0.04
17
98
12
62
1.96
1.28
2.2
1.9
8.13
10.29
%
0.90
12
62
26
170
1.55
1.28
1.4
1.2
—
—
—
0
0
15
84
1.81
1.28
1.5
1.3
—
—
—
0
0
83
668
1.28
1.26
1.6
1.8
—
—
—
0
0
8
160
0.49
1.26
4.5
12.5
—
—
—
0
0
9
45
2.02
1.23
2.4
1.9
—
—
—
0
0
5
19
2.65
1.22
1.6
1.2
5.94
7.34
mmol/l
—
5
19
170
1488
1.20
1.20
3.3
3.5
0.00
0.08
estimate
0.86
65
478
15
86
1.76
1.20
3.7
2.7
4.27
4.75
e9/l
0.59
15
86
136
1166
1.22
1.19
4.5
4.2
86.62
357.56
ng/l
3.01
111
984
0
33
0.00
1.16
0.0
1.1
—
—
—
0
0
20
126
1.61
1.16
4.0
3.7
—
—
—
0
0
16
95
1.70
1.15
1.1
1.1
—
—
—
0
0
14
80
1.77
1.13
1.4
1.5
—
—
—
0
0
77
624
1.27
1.12
4.1
2.6
65.40
68.30
e9/l
0.25
49
481
68
544
1.28
1.10
2.6
2.3
84.94
125.73
ug/g
1.25
49
439
7
32
2.20
1.08
1.1
1.6
—
—
—
0
0
7
32
2.20
1.08
1.3
1.5
—
—
—
0
0
58
457
1.30
1.06
3.6
4.2
98.53
93.50
ng/l
0.14
46
407
219
1980
1.17
1.05
3.5
3.3
1980.08
1466.07
ng/l
0.71
189
1735
17
262
0.64
1.03
1.8
2.0
—
—
—
0
0
10
53
1.90
1.02
2.2
2.1
—
—
—
0
0
9
48
1.89
1.01
1.1
1.3
—
—
—
0
0
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
64
517
1.27
0.97
1.5
1.5
—
—
—
0
0
28
199
1.43
0.97
4.7
1.8
13.62
9.42
iu/ml
—
6
52
20
133
1.52
0.95
2.1
2.4
90.97
88.75
%
0.88
20
128
30
217
1.40
0.95
1.0
1.1
—
—
—
0
0
7
37
1.90
0.94
1.0
1.1
—
—
—
0
0
10
55
1.83
0.92
1.0
1.1
0.45
1.66
u/ml
—
5
29
16
243
0.65
0.92
5.4
4.2
24.51
25.01
mmol/l
0.35
16
228
6
28
2.15
0.91
1.0
1.1
—
7.21
—
0
8
12
71
1.70
0.89
1.2
1.2
2.80
6.97
u/ml
—
5
30
12
72
1.68
0.85
2.2
2.3
—
—
—
0
0
64
528
1.24
0.84
2.9
2.5
32.34
34.40
u/l
0.21
56
445
15
97
1.56
0.82
3.3
3.5
9.12
10.17
pmol/l
0.18
15
97
38
295
1.31
0.80
2.3
2.9
—
—
—
0
0
136
1209
1.16
0.80
1.6
1.8
423.49
5740611.88
pmol/l
0.50
101
993
10
58
1.74
0.80
1.5
1.3
—
—
—
0
0
54
654
0.81
0.77
3.5
3.9
7.37
7.39
ph
0.48
23
383
39
307
1.29
0.76
1.3
1.3
—
—
—
0
0
9
54
1.68
0.75
1.3
1.3
—
—
—
0
0
10
160
0.62
0.74
4.1
4.9
—
—
—
0
0
9
56
1.62
0.72
1.1
1.3
—
—
—
0
0
10
60
1.68
0.72
1.5
1.1
—
—
—
0
0
175
1599
1.14
0.70
3.7
4.1
0.00
0.01
estimate
0.78
75
546
9
146
0.61
0.70
1.8
2.0
12.61
13.32
mg/l
—
9
134
22
295
0.74
0.69
3.2
3.9
1.02
1.02
ratio
0.08
15
278
9
59
1.53
0.68
1.3
1.1
—
—
—
0
0
17
119
1.44
0.67
3.8
2.6
62.00
60.11
%
0.33
17
119
5
92
0.54
0.67
1.2
1.3
—
—
—
0
0
5
92
0.54
0.67
1.2
1.3
—
—
—
0
0
10
62
1.62
0.65
1.2
1.3
—
—
—
0
0
8
131
0.61
0.64
1.0
1.1
—
—
—
0
0
16
112
1.44
0.64
1.2
1.2
3.71
3.79
mmol/l
0.08
16
105
123
1106
1.14
0.63
1.3
1.3
1.52
1.43
u/ml
0.04
33
288
193
1787
1.12
0.62
3.2
3.5
34.78
34.70
u/l
0.01
184
1688
293
2777
1.11
0.61
3.8
4.1
0.00
0.00
estimate
-0.00
80
601
5
30
1.67
0.61
1.6
1.4
—
—
—
0
0
216
2017
1.11
0.60
4.1
3.4
7.78
7.69
mmol/l
0.10
166
1690
14
97
1.45
0.59
2.1
2.8
—
—
—
0
0
212
1979
1.11
0.59
4.2
3.5
53.83
50.69
mg/l
0.07
136
1330
0
23
0.00
0.58
0.0
1.2
—
179.03
—
0
23
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
6
36
1.67
0.57
1.5
2.9
0.83
0.89
index
—
6
36
295
2807
1.10
0.56
3.8
4.1
0.01
2.65
estimate
0.49
82
613
5
90
0.55
0.56
1.2
1.3
—
—
—
0
0
127
1156
1.13
0.55
5.5
5.0
—
—
—
0
0
109
983
1.13
0.54
2.8
2.7
2.27
2.26
g/l
0.05
104
910
10
146
0.68
0.52
1.0
1.1
—
—
—
0
0
6
96
0.62
0.52
1.2
1.1
—
—
—
0
0
55
474
1.18
0.51
5.1
4.9
0.14
0.12
%
0.05
14
148
30
243
1.25
0.50
1.3
1.3
—
—
—
0
0
181
1691
1.10
0.49
3.2
3.4
—
—
—
0
0
77
686
1.14
0.47
1.4
1.3
429.47
460.13
titre
0.08
19
155
33
273
1.22
0.47
2.6
2.5
—
—
—
0
0
295
2826
1.09
0.46
3.8
4.1
0.04
0.54
estimate
0.46
75
569
5
81
0.61
0.46
1.4
1.5
—
—
—
0
0
5
81
0.61
0.46
1.4
1.5
—
—
—
0
0
5
81
0.61
0.46
1.4
1.5
—
—
—
0
0
5
81
0.61
0.46
1.4
1.5
—
—
—
0
0
62
546
1.15
0.45
9.2
9.5
—
—
—
0
0
74
662
1.14
0.43
3.1
3.1
3.83
5.59
e9/l
1.26
59
570
14
104
1.35
0.43
1.2
1.2
—
—
—
0
0
5
31
1.62
0.43
1.8
1.5
—
—
—
0
0
6
92
0.65
0.42
1.2
1.0
—
—
—
0
0
13
96
1.36
0.42
1.5
1.3
91.00
269.56
miu/ml
—
6
38
5
34
1.47
0.40
2.0
2.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
332.60
—
0
10
5
35
1.43
0.39
3.6
4.1
77.60
117.34
nmol/l
—
5
35
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
17
133
1.29
0.39
1.9
2.0
215.24
221.01
pmol/l
0.14
17
124
26
312
0.83
0.39
4.5
3.9
—
—
—
0
0
5
36
1.39
0.38
2.0
1.4
—
—
—
0
0
5
36
1.39
0.38
1.4
1.8
14.14
9.19
umol/l
—
5
27
90
827
1.10
0.35
5.5
6.2
1.02
1.03
mmol/l
0.07
84
765
211
2017
1.07
0.33
5.5
4.2
7.51
8.91
mg/mmol
0.27
130
1309
25
210
1.20
0.33
1.4
1.2
—
—
—
0
0
18
146
1.24
0.32
1.9
2.1
133.22
128.08
g/l
0.38
18
112
15
119
1.27
0.32
3.7
4.2
43.75
27.87
mg/l
—
8
87
56
506
1.12
0.30
5.0
4.7
0.90
0.93
%
0.03
15
179
12
93
1.30
0.30
1.8
1.7
0.72
0.90
g/l
—
7
76
54
488
1.12
0.29
5.2
5.1
0.31
0.15
%
0.20
13
137
65
594
1.11
0.29
1.8
2.4
0.21
0.20
g/l
0.15
65
553
31
270
1.16
0.28
2.4
2.2
0.00
0.01
estimate
—
10
75
119
1262
0.93
0.28
3.7
4.1
—
0.17
—
0
18
19
158
1.21
0.28
2.3
1.6
—
—
—
0
0
8
62
1.29
0.28
1.9
2.2
—
—
—
0
0
8
64
1.25
0.27
4.8
3.5
2.36
6.48
nmol/l
—
8
64
77
830
0.92
0.27
1.4
1.3
2.48
14.38
u/ml
4.07
28
308
11
139
0.79
0.27
1.0
1.2
—
—
—
0
0
26
225
1.16
0.26
1.2
1.1
—
30.17
—
0
6
8
67
1.20
0.26
1.4
1.1
—
—
—
0
0
236
2281
1.06
0.26
3.9
4.3
35.31
41.78
ng/l
0.43
186
1799
25
216
1.16
0.26
3.2
3.5
535.44
235.44
mg/l
—
9
95
127
1204
1.07
0.26
2.4
1.7
1.51
1.54
mg/l
0.03
91
961
9
72
1.25
0.25
2.9
2.7
—
—
—
0
0
14
114
1.23
0.25
1.3
1.2
—
—
—
0
0
53
484
1.10
0.25
4.8
4.6
0.67
0.50
%
0.20
12
165
40
360
1.12
0.24
1.2
1.2
—
—
—
0
0
6
81
0.74
0.24
2.0
2.1
10.50
10.69
mmol/l
—
6
81
6
82
0.73
0.24
2.7
3.1
1.21
1.19
mmol/l
—
6
82
6
83
0.72
0.24
2.7
3.1
106.17
105.07
mmol/l
—
6
83
6
83
0.72
0.24
2.7
3.1
3.92
4.06
mmol/l
—
6
83
15
124
1.22
0.24
5.1
4.5
3.55
2.19
mmol/l
—
8
81
51
555
0.91
0.23
1.8
2.6
9.65
7.73
ug/l
0.35
42
502
5
40
1.25
0.22
1.0
1.1
105.20
95.13
pmol/l
—
5
40
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
13
107
1.22
0.21
6.2
2.0
0.97
0.87
%
—
8
80
5
42
1.19
0.21
3.6
3.5
6.79
41.65
mg/l
—
5
36
0
11
0.00
0.21
0.0
11.9
—
5.62
—
0
11
0
10
0.00
0.21
0.0
1.1
—
0.82
—
0
5
0
12
0.00
0.21
0.0
5.9
—
9.07
—
0
12
11
89
1.24
0.21
5.5
5.2
8.50
11.73
mg/l
2.65
11
83
47
432
1.10
0.20
9.9
9.6
0.98
1.32
%
3.24
47
427
6
48
1.25
0.20
1.2
1.3
—
—
—
0
0
183
1771
1.05
0.19
4.8
4.5
—
—
—
0
0
6
52
1.16
0.19
1.0
1.2
—
—
—
0
0
6
53
1.13
0.18
1.2
1.2
—
—
—
0
0
111
1061
1.06
0.18
2.9
2.7
11.89
12.70
umol/l
0.58
106
991
5
66
0.76
0.17
1.2
1.3
—
101.73
—
0
6
12
140
0.85
0.15
1.3
1.2
—
—
—
0
0
9
83
1.09
0.14
1.1
1.1
1.67
1.53
g/l
—
9
77
72
756
0.95
0.14
8.1
8.0
0.72
0.86
mmol/l
0.15
62
622
51
481
1.07
0.13
1.7
1.5
—
—
—
0
0
176
1799
0.97
0.11
3.4
2.6
58.01
106.38
u/l
0.56
156
1679
15
134
1.12
0.11
4.2
3.5
56.29
427.25
u/ml
1.16
15
125
29
310
0.93
0.10
1.5
1.4
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
12
106
1.13
0.10
1.3
1.2
213.48
38.43
u/l
0.59
12
94
5
48
1.04
0.09
2.2
3.0
8.40
8.64
mmol/l
—
5
48
6
56
1.07
0.08
1.2
1.1
—
—
—
0
0
6
56
1.07
0.08
2.3
2.4
—
54.05
—
0
8
6
57
1.05
0.08
1.2
1.1
—
—
—
0
0
10
113
0.88
0.08
1.3
1.7
—
—
—
0
0
5
62
0.80
0.08
1.0
1.4
—
—
nmol/l
—
0
0
27
287
0.94
0.08
1.9
1.4
—
—
—
0
0
7
64
1.09
0.08
3.1
2.5
465.43
1167.58
mg
—
7
64
87
894
0.97
0.08
1.4
1.3
35.14
40.95
iu/ml
0.17
30
291
8
78
1.03
0.07
1.0
1.2
—
40.29
—
0
17
8
95
0.84
0.06
8.1
4.5
0.69
1.26
%
—
8
87
16
148
1.08
0.06
1.4
1.6
—
—
—
0
0
29
277
1.05
0.05
2.0
1.8
3.68
3.48
mmol/l
0.40
21
219
27
260
1.04
0.03
1.7
1.6
—
—
—
0
0
42
431
0.97
0.03
3.6
3.7
7.41
7.42
ph
0.42
37
363
53
519
1.02
0.03
2.0
2.1
0.00
0.03
estimate
—
10
96
13
122
1.07
0.02
2.5
1.6
—
—
—
0
0
67
660
1.02
0.02
3.4
2.9
6.75
8.82
umol/l
0.51
61
597
45
441
1.02
0.02
2.2
2.7
6.25
6.06
ph
0.65
24
311
11
103
1.07
0.02
2.0
1.4
—
—
—
0
0
34
348
0.98
0.01
2.1
2.7
0.63
0.62
%
0.08
34
348
209
2082
1.01
0.01
3.6
4.1
0.00
0.03
estimate
1.71
69
506
12
114
1.05
0.00
1.4
1.2
0.89
0.90
g/l
0.02
12
114
15
156
0.96
0.00
1.7
1.2
—
104.38
—
0
16
222
2226
1.00
0.00
3.3
3.7
6.06
6.21
ph
1.21
108
1230
10
103
0.97
0.00
1.1
1.1
1.52
1.52
g/l
—
10
103
10
103
0.97
0.00
1.7
1.2
183.80
304.07
u/ml
—
5
56
10
102
0.98
0.00
2.6
2.7
—
—
—
0
0
76
765
0.99
0.00
7.7
7.9
7.42
7.41
ph
0.03
34
445
22
221
1.00
0.00
1.5
1.6
0.34
0.36
mg/l
—
10
103
44
441
1.00
0.00
3.6
3.6
5.16
5.12
kpa
0.13
44
427
6
64
0.94
0.00
9.0
4.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
0.92
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
27.87
—
0
7
6
69
0.87
-0.00
1.7
1.4
0.68
0.58
nmol/l
—
6
63
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
—
—
—
0
0
29
290
1.00
-0.00
2.2
1.9
7.65
2.62
ug/l
0.53
23
260
0
9
0.00
-0.00
0.0
2.3
—
2.00
—
0
9
6
62
0.97
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
14.00
—
0
5
7
70
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.90
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
64.00
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
36.13
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
1.9
1.9
88.34
89.76
%
—
8
79
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_MELANOMA_TRUNK – Melanoma in situ of trunk

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).