Atrial septal defect, secundum type

Q17_ATRIAL_SEPTAL_DEFECT_SECUNDUM_TYPE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q21.10
  • Hospital discharge: ICD-9 7455A
  • Hospital discharge: ICD-8 74642
  • Cause of death: ICD-10 Q21.10
  • Cause of death: ICD-9 7455A
  • Cause of death: ICD-8 74642

2 out of 7 registries used, show all original rules.

1191

4. Check minimum number of events

None

1191

5. Include endpoints

None

1191

6. Filter based on genotype QC (FinnGen only)

1066

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1066 713 353
Unadjusted period prevalence (%) 0.22 0.25 0.16
Median age at first event (years) 21.40 22.87 18.45

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1113
Matched controls
11091
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q21.10
ICD-10 Finland
Persistent ostium secundum
4503599627370496.0
307.7
841
*
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
180.5
307.7
182
12
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
25.0
307.7
440
283
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
+∞
253.9
234
*
XF620
NOMESCO Finland
Examination of circulation with color method
104.6
250.9
130
14
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
14.8
224.1
217
179
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.5
215.6
570
1537
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
30.1
211.2
143
54
Q21.19
ICD-10 Finland
Atrial septal defect NOS
340.6
200.0
197
7
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
6.6
191.2
412
904
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
45.5
167.6
100
24
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
40.2
155.9
96
26
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
155.8
146
*
B01AA03
ATC
warfarin; systemic
6.4
153.3
314
644
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
34.8
145.1
93
29
201
Kela drug reimbursment
Chronic cardiac insufficiency
10.1
133.4
163
186
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
126.4
119
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
4.9
109.5
297
763
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
15.7
104.8
93
64
XF400
NOMESCO Finland
ECG with 12 standard connections
4.3
103.4
348
1053
C01AA05
ATC
digoxin; systemic
8.1
101.7
146
202
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
5.5
94.2
207
441
XF404
NOMESCO Finland
Ambulatory ECG
5.3
86.2
197
433
TFP20
NOMESCO Finland
Cardiodefibrillation
6.8
86.0
146
242
31
HP
Congenital heart failure surgery
117.4
81.1
87
8
5253
FHL
Cardiac lung machine
48.9
80.2
47
10
5205
FHL
ASD blockage, secondary defect
+∞
74.7
71
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
74.3
632
3305
207
Kela drug reimbursment
Chronic arrhythmias
4.3
70.0
210
570
FM2CE, ,
NOMESCO Finland
6.6
69.9
120
200
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.7
66.7
174
423
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
14.2
61.4
57
42
C03CA01
ATC
furosemide; systemic
3.1
60.8
331
1319
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
28.2
60.2
41
15
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
55.3
272
1016
61
HP
Catheterization and pressure measurement of the left side of the heart
17.0
54.8
46
28
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
9.4
53.0
65
73
TPH07
NOMESCO Finland
Cathetrisation of artery
3.6
52.9
203
648
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.2
52.9
253
927
WX872
NOMESCO Finland
Intensive care
6.2
52.7
94
162
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
6.2
50.0
89
153
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.5
50.0
101
196
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.6
49.7
186
583
Q25.1
ICD-10 Finland
Coarctation of aorta
15.5
47.7
42
28
K78
ICPC
Atrial fibrillation/flutter
5.1
47.6
107
228
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
6.0
47.0
86
152
XFE00
NOMESCO Finland
Epicardial ultrasonography
9.8
44.3
52
55
XF402
NOMESCO Finland
ECG with work load test
3.8
44.2
146
419
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
99.9
44.1
48
5
I50.9
ICD-10 Finland
Heart failure, unspecified
3.7
43.5
155
468
Q21.1
ICD-10 Finland
Atrial septal defect
+∞
42.9
41
*
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
6.9
42.3
67
102
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
42.0
389
1980
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.5
41.7
163
523
I48.2
ICD-10 Finland
Chronic atrial fibrillation
6.3
41.2
71
118
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
5.5
40.1
80
153
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
211.9
40.1
41
*
Q23.11
ICD-10 Finland
Bicuspid aortic valve
11.1
40.0
43
40
C07AB07
ATC
bisoprolol; oral
2.3
39.7
476
2700
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.6
39.5
100
235
APK
HP
ASD closure
+∞
38.7
37
*
C03DA01
ATC
spironolactone; oral
3.3
38.2
162
545
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
10.6
37.8
42
41
I49.5
ICD-10 Finland
Sick sinus syndrome
6.3
37.7
65
108
FFC50
NOMESCO Finland
Closure of ostium secundum type ASD using patch
378.2
37.2
37
*
I50.0
ICD-10 Finland
Congestive heart failure
4.6
36.9
91
209
62
HP
Catheterization and pressure measurement of the right side of the heart
70.5
36.1
41
6
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
35.8
329
1650
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
346.2
34.1
34
*
I48.1
ICD-10 Finland
Persistent atrial fibrillation
5.7
33.6
64
117
XF640, ,
NOMESCO Finland
7.4
33.1
49
69
XX3BT
NOMESCO Finland
Other labeling with X-ray guidance
8.1
32.4
44
56
C07AA07
ATC
sotalol; systemic
6.1
32.2
57
97
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
73.9
32.0
36
5
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
31.5
478
2912
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
320.4
30.9
31
*
AF1
HP
Surgery of congenital heart defect
164.0
30.8
32
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
6.0
30.6
55
95
B01AF02
ATC
apixaban; oral
3.1
30.3
143
510
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.4
29.7
114
359
Q25.0
ICD-10 Finland
Patent ductus arteriosus
7.6
29.3
42
57
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
9.2
28.6
35
39
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
+∞
28.2
27
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.8
28.1
91
256
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
27.5
425
2575
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
9.4
27.4
33
36
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
27.4
94
275
I34.1
ICD-10 Finland
Mitral (valve) prolapse
6.1
27.4
48
81
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
8.1
27.3
37
47
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.8
27.1
147
565
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.3
25.7
103
333
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
25.2
180
794
XF600
NOMESCO Finland
Bloodpressure measurement
2.8
24.0
134
522
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.9
23.9
72
192
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
4.9
23.4
53
113
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
9.5
22.6
27
29
Z2221
NOMESCO Finland
Medical doctor
2.0
22.5
349
2089
I44.2
ICD-10 Finland
Atrioventricular block, complete
5.8
22.1
41
73
WX892
NOMESCO Finland
Monitored bed care
2.8
22.1
118
449
7456A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[DEFECTUS SEPTI ATRIORUM NUD]
+∞
21.9
21
*
TFP34
NOMESCO Finland
Electrophysiological investigation
4.4
21.4
55
130
Q21.21
ICD-10 Finland
Atrioventricular duct
44.1
21.4
26
6
XF622
NOMESCO Finland
Measurement of minute volume of heart
18.7
20.4
31
17
I48.4
ICD-10 Finland
Atypical atrial flutter
27.5
20.1
27
10
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
19.8
19
*
C01BD01
ATC
amiodarone; systemic
5.4
19.7
39
74
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
14.6
18.1
30
21
C01BC04
ATC
flecainide; systemic
4.2
18.0
48
117
I44.1
ICD-10 Finland
Atrioventricular block, second degree
6.6
17.9
29
45
WX882
NOMESCO Finland
High dependency care
2.7
17.8
99
384
ZXD05
NOMESCO Finland
Urgent procedure
1.8
17.4
332
2095
AP2
HP
Catheterization of the right side of the heart
42.6
17.3
21
5
Q20.1
ICD-10 Finland
Double outlet right ventricle
31.9
17.0
22
7
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
17.7
16.9
26
15
Q21.0
ICD-10 Finland
Ventricular septal defect
21.2
16.0
23
11
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
14.7
15.8
26
18
I47.1
ICD-10 Finland
Supraventricular tachycardia
3.0
15.8
71
245
I50.1
ICD-10 Finland
Left ventricular failure
3.8
15.8
48
129
AN1
HP
Coronary angiography
2.7
15.8
86
330
AP3
HP
Catheterization of the right and left side of the heart
60.7
15.8
18
*
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
161.6
15.5
16
*
B01AB05
ATC
enoxaparin; parenteral
1.8
15.4
280
1732
WX402
NOMESCO Finland
General anaesthesia
1.8
15.2
301
1909
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
15.2
14.9
24
16
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
14.6
257
1570
R06.0
ICD-10 Finland
Dyspnoea
1.8
14.5
276
1728
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.9
14.3
31
64
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
22.5
14.2
20
9
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
13.6
14.2
24
18
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.1
13.9
146
749
R04.0
ICD-10 Finland
Epistaxis
2.6
13.9
86
352
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.6
13.9
82
328
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
20.3
13.8
20
10
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
5.8
13.6
25
44
Q21.29
ICD-10 Finland
Atrioventricular septal defect UNS
+∞
13.5
13
*
Q87.14
ICD-10 Finland
Noonan's syndrome
34.4
13.5
17
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
13.2
190
1086
I49.1
ICD-10 Finland
Atrial premature depolarization
3.3
13.2
49
151
Q90.9
ICD-10 Finland
Down syndrome, unspecified
40.4
13.2
16
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
12.3
13.1
23
19
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
5.0
13.1
28
57
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
16.9
13.0
20
12
C07AB02
ATC
metoprolol; systemic
2.0
12.9
161
878
FFC32
NOMESCO Finland
Percutaneous transluminal closure of sinus venosus type ASD
+∞
12.5
12
*
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
24.5
12.5
17
7
RS224, ,
NOMESCO Finland
4.9
12.4
27
56
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.9
12.4
36
94
R4110
NOMESCO Finland
Physiotherapy
1.7
12.3
315
2127
Z31.5
ICD-10 Finland
Genetic counselling
2.3
12.3
101
470
Z98.8
ICD-10 Finland
Other specified postsurgical states
4.5
12.1
29
65
I48.3
ICD-10 Finland
Typical atrial flutter
11.2
12.0
22
20
Q26.1
ICD-10 Finland
Persistent left superior vena cava
21.5
12.0
17
8
ZXE00
NOMESCO Finland
One hour or less
1.6
11.9
432
3169
Q21.12
ICD-10 Finland
Defective sinus venosus
47.0
11.9
14
*
Q22.5
ICD-10 Finland
Ebstein anomaly
47.0
11.9
14
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
47.0
11.9
14
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
11.6
227
1421
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
11.5
11
*
81
HP
Angiography of the heart and coronary arteries
3.2
11.1
43
136
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
43.6
10.9
13
*
K80
ICPC
Cardiac arrhythmia NOS
2.2
10.8
90
420
Z3231
NOMESCO Finland
Registered nurse
1.6
10.8
338
2385
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
28.2
10.7
14
5
Q21.30
ICD-10 Finland
Tetralogy of Fallot
13.0
10.6
18
14
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
60.4
10.6
12
*
B01AE07
ATC
dabigatran etexilate; oral
3.6
10.6
35
100
342
Kela drug reimbursment
Dronedarone
11.3
10.5
19
17
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
10.5
330
2328
I47.2
ICD-10 Finland
Ventricular tachycardia
4.5
10.5
25
56
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
10.4
10
*
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
5.2
10.3
21
41
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
23.5
10.2
14
6
FM1CD
NOMESCO Finland
Very extensive CT of heart
23.5
10.2
14
6
TFP35
NOMESCO Finland
Electroanatomical mapping
4.6
10.2
24
53
B01AC04
ATC
clopidogrel; oral
2.0
10.2
117
618
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
10.1
242
1597
C01BD07
ATC
dronedarone; oral
12.3
9.8
17
14
FFC42
NOMESCO Finland
Percutaneous closure of patent foramen ovale
55.3
9.6
11
*
K84
ICPC
Heart disease other
3.8
9.6
29
78
51
HP
Other heart surgery
100.5
9.4
10
*
Q90
ICD-10 Finland
Down syndrome
100.5
9.4
10
*
APJ
HP
PFO closure
100.5
9.4
10
*
5207
FHL
VSD closure
+∞
9.4
9
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
9.4
9
*
I51.0
ICD-10 Finland
Cardiac septal defect, acquired
+∞
9.4
9
*
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
4.1
9.2
25
62
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.6
9.2
30
85
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
9.2
248
1681
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.0
9.0
25
63
I97.0
ICD-10 Finland
Postcardiotomy syndrome
15.7
9.0
14
9
B01AF01
ATC
rivaroxaban; oral
2.0
9.0
102
537
WX704
NOMESCO Finland
Intubation
2.1
8.9
89
447
Q26.3
ICD-10 Finland
Partial anomalous pulmonary venous connection
24.1
8.9
12
5
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
24.1
8.9
12
5
C09AA05
ATC
ramipril; oral
1.7
8.9
174
1086
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.2
8.8
35
113
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
9.5
8.8
17
18
I44.0
ICD-10 Finland
Atrioventricular block, first degree
7.2
8.7
20
28
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
7.7
8.6
19
25
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
8.6
135
789
C07AB03
ATC
atenolol; systemic
2.7
8.6
47
181
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
2.9
8.6
39
136
K77
ICPC
Heart failure
4.4
8.6
21
48
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
27.6
8.5
11
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
90.4
8.4
9
*
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
90.4
8.4
9
*
602
Kela drug reimbursment
Children's severe malnutrition
2.9
8.3
38
133
250, ,
Kela drug reimbursment
4.1
8.2
22
54
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
8.2
58
253
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
3.7
8.2
25
68
K90
ICPC
Stroke/cerebrovascular accident
3.5
8.1
27
78
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
2.6
8.0
44
170
PD5BD
NOMESCO Finland
Extensive CT of aorta
6.3
8.0
20
32
R50.9
ICD-10 Finland
Fever, unspecified
1.6
8.0
208
1394
I50
ICD-10 Finland
Heart failure
3.5
7.9
27
79
R62.0
ICD-10 Finland
Delayed milestone
2.5
7.9
48
195
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
7.9
311
2282
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.6
7.9
43
166
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
9.5
7.8
15
16
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
45.1
7.7
9
*
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
45.1
7.7
9
*
J01CA04
ATC
amoxicillin; systemic
1.6
7.7
945
8607
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.5
7.6
18
40
I27.0
ICD-10 Finland
Primary pulmonary hypertension
25.1
7.6
10
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
8.9
7.5
15
17
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
7.5
96
527
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
7.5
76
385
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
80.3
7.4
8
*
SPAT1097
SPAT
Recording of ECG
1.8
7.4
111
641
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
6.0
7.4
19
32
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
7.3
58
266
Q21.2
ICD-10 Finland
Atrioventricular septal defect
+∞
7.3
7
*
FM2FN
NOMESCO Finland
Intra cardiac shunt isotope imaging
+∞
7.3
7
*
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
10.9
7.3
13
12
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
15.8
7.2
11
7
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
7.3
7.2
16
22
Q24.6
ICD-10 Finland
Congenital heart block
30.1
7.1
9
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
20.1
7.1
10
5
K99
ICPC
Cardiovascular disease other
3.8
7.1
21
56
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
3.8
7.1
21
56
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
8.8
7.0
14
16
AA1AD
NOMESCO Finland
CT of head and brain
1.5
7.0
226
1587
J96.1
ICD-10 Finland
Chronic respiratory failure
3.9
7.0
20
52
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.0
6.9
29
97
C09DX04
ATC
valsartan and sacubitril; oral
7.6
6.9
15
20
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
6.8
80
427
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.7
6.8
127
781
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
40.2
6.7
8
*
I36.0
ICD-10 Finland
Nonrheumatic tricuspid (valve) stenosis
40.2
6.7
8
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
16.7
6.7
10
6
GE1BE
NOMESCO Finland
Mediastinal ultrasound examinaiton through oesophagus
16.7
6.7
10
6
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.8
6.7
99
568
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
3.9
6.7
19
49
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
3.9
6.7
19
49
F83
ICD-10 Finland
Mixed specific developmental disorders
2.5
6.7
39
156
Z95.9
ICD-10 Finland
Presence of cardiac and vascular implant and graft, unspecified
22.6
6.7
9
*
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
22.6
6.7
9
*
AR5
HP
Catheter ablation of arrhythmia, target: atrial flutter
22.6
6.7
9
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
12.3
6.6
11
9
4122
FHL
Tympanostomy (tympanic tube)
3.5
6.5
22
64
P85
ICPC
Mental retardation
3.4
6.5
23
69
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.5
455
3682
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.5
6.5
38
152
AS4
HP
Physiological pacemaker insertion DDD (R)
6.9
6.5
15
22
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.7
6.5
34
129
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
70.0
6.4
7
*
Q90.1
ICD-10 Finland
Trisomy 21, mosaicism (mitotic nondisjunction)
70.0
6.4
7
*
74690
ICD-8 Finland
Congenital anomalies of heart, Maleformatio cordis suspecta
70.0
6.4
7
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
70.0
6.4
7
*
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
70.0
6.4
7
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
70.0
6.4
7
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
6.4
172
1157
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
14.3
6.4
10
7
P07.3
ICD-10 Finland
Other preterm infants
2.8
6.3
30
108
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
6.3
736
8121
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
11.1
6.3
11
10
WZC30
NOMESCO Finland
Teaching
1.6
6.3
148
966
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.0
6.3
27
92
APX
HP
Other cardiac catheter operation
+∞
6.2
6
*
7463A
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[STENOSIS VALVULAE AORTAE CONGENITA]
+∞
6.2
6
*
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.0
6.2
69
361
74
HP
Initial installation of the atrial pacemaker
26.7
6.2
8
*
FFC96
NOMESCO Finland
Other closure of isolated atrial septal defect
26.7
6.2
8
*
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
7.0
6.2
14
20
H53.0
ICD-10 Finland
Amblyopia ex anopsia
2.9
6.2
28
98
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
6.2
65
334
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
3.5
6.1
20
57
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
6.1
85
479
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.9
6.1
28
99
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
12.6
6.1
10
8
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
8.6
6.0
12
14
K83
ICPC
Heart valve disease NOS
8.6
6.0
12
14
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
10.1
6.0
11
11
Q20.48
ICD-10 Finland
Single ventricle
10.1
6.0
11
11
UGC02
NOMESCO Finland
Rigid bronchoscopy
5.2
6.0
17
33

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
536
2069
4.05
114.95
6.0
3.7
1315.62
1085.59
ng/l
0.59
484
1729
674
3526
3.29
81.63
27.8
10.5
1.45
1.17
inr
23.38
581
2926
215
541
4.67
79.65
3.3
4.2
193.06
204.34
ng/l
0.14
201
494
360
1482
3.10
62.76
3.7
3.9
30.91
29.88
s
2.05
349
1452
342
1571
2.69
46.57
4.2
3.8
1256.28
519.91
ng/l
1.16
275
1064
418
2323
2.27
35.80
2.6
2.7
—
—
—
0
0
427
2490
2.15
31.57
6.4
6.1
80.97
90.79
%
11.38
420
2445
479
2984
2.05
29.11
2.7
2.7
—
—
—
0
0
145
554
2.85
27.07
1.8
2.4
16.15
6.84
ug/l
2.94
125
489
32
36
9.09
25.93
3.3
8.4
4.96
4.93
kpa
0.05
32
36
609
4256
1.94
25.45
3.2
3.0
—
—
estimate
—
0
0
287
1552
2.14
24.79
6.9
7.2
0.82
0.82
mmol/l
0.60
275
1486
186
883
2.32
21.90
18.7
10.4
0.94
0.51
mmol/l
0.85
171
733
186
889
2.30
21.53
18.8
10.4
7.41
7.41
ph
0.20
81
451
131
536
2.63
21.25
4.3
5.1
21.47
21.85
s
0.46
113
501
57
146
4.05
20.01
1.2
1.2
—
—
—
0
0
386
2521
1.80
18.20
5.1
3.3
—
0.71
—
0
7
734
5766
1.79
18.12
5.1
3.6
—
8418.17
—
0
12
709
5586
1.73
16.56
9.9
6.4
6.26
6.39
mmol/l
1.15
684
5257
417
2859
1.73
16.18
4.7
3.4
47.21
70.60
ng/l
0.37
284
1797
27
20
13.76
16.00
2.7
2.8
99.00
94.60
g/l
0.78
27
20
222
1287
1.90
14.95
18.4
11.4
—
—
—
0
0
45
126
3.67
13.98
2.4
2.4
—
—
—
0
0
38
96
4.05
13.62
3.2
3.4
0.81
0.84
nmol/l
0.13
31
80
55
180
3.15
13.41
1.3
1.3
4.88
5.43
u/ml
0.10
26
82
224
1354
1.81
13.06
3.6
3.0
20.77
22.58
%
1.36
211
1294
588
4591
1.59
12.63
8.5
7.3
16.77
14.44
umol/l
1.09
555
4359
238
1481
1.76
12.53
3.4
2.9
2.47
2.42
g/l
0.67
223
1397
358
2499
1.63
12.22
2.7
2.4
221.51
235.59
u/l
0.13
337
2392
565
4392
1.57
12.21
14.9
10.0
1.21
1.22
mmol/l
4.50
536
4120
74
306
2.51
11.69
2.1
2.2
1.18
1.37
g/l
1.10
60
275
1025
9335
2.19
11.58
25.9
16.7
3.98
3.95
mmol/l
2.77
1020
9137
177
1034
1.84
11.43
10.8
9.4
—
—
—
0
0
504
3859
1.55
11.37
5.9
6.3
36.37
36.73
g/l
0.74
477
3667
247
1594
1.70
11.30
3.5
2.9
12.63
13.61
umol/l
1.35
232
1513
319
2212
1.61
10.98
4.8
4.4
—
—
—
0
0
27
64
4.28
10.54
1.7
1.5
—
—
—
0
0
203
1265
1.73
10.48
10.7
9.1
7.41
7.41
ph
0.46
176
1017
227
1460
1.69
10.44
6.9
8.9
7.38
7.37
ph
0.80
159
927
161
943
1.82
10.26
22.1
11.4
1.23
1.35
mmol/l
0.72
161
928
25
57
4.45
10.24
1.9
1.4
82532.50
53009.31
e6/l
0.18
16
32
223
1435
1.69
10.22
6.9
8.8
1.77
1.37
mmol/l
1.01
197
1209
243
1602
1.65
10.14
9.3
9.4
1.22
1.19
mmol/l
0.68
235
1519
42
143
3.00
9.63
7.5
7.2
11.74
11.28
mg/l
0.19
36
136
26
65
4.06
9.49
1.8
1.4
1585.65
2516.30
e6/l
0.45
20
46
293
2088
1.54
8.65
3.2
2.6
1.27
1.37
mg/l
0.22
215
1600
588
4824
1.46
8.56
12.6
9.9
1.21
1.22
mmol/l
2.78
522
4292
22
56
3.97
7.86
2.0
1.4
—
—
—
0
0
76
385
2.04
7.46
1.2
1.7
—
14.32
—
0
12
1045
9810
2.01
7.34
23.3
16.7
69.77
68.47
umol/l
0.62
1040
9698
178
1178
1.60
7.14
3.5
4.8
1.95
1.64
%
2.12
166
1098
68
341
2.05
6.88
1.1
1.3
—
—
—
0
0
187
1268
1.56
6.75
2.6
2.0
—
—
—
0
0
140
888
1.65
6.65
3.1
3.9
77.08
68.42
e9/l
1.36
103
593
20
54
3.74
6.62
2.2
1.7
—
—
—
0
0
40
163
2.50
6.61
7.3
5.3
1.71
2.27
mmol/l
0.87
26
100
1020
9550
1.77
6.53
20.1
14.3
24.90
22.29
mg/l
1.99
859
7528
464
3781
1.38
6.33
7.6
8.8
—
—
—
0
0
1031
9731
1.76
5.74
17.9
11.9
—
—
—
0
0
630
5454
1.35
5.57
7.4
8.2
0.57
0.57
e9/l
0.30
548
4624
642
5575
1.35
5.56
7.4
8.3
1.90
2.12
e9/l
3.51
570
4862
16
32
5.04
5.55
1.1
1.3
31.69
28.06
s
0.72
16
32
630
5456
1.35
5.55
7.4
8.3
0.04
0.04
e9/l
1.68
550
4625
335
2643
1.38
5.39
3.1
2.8
2.98
2.68
mg/l
1.62
299
2331
53
267
2.03
5.35
1.2
1.3
—
7.93
—
0
6
381
3084
1.35
5.16
1.5
1.6
—
—
—
0
0
644
5636
1.33
5.07
7.8
8.8
0.18
0.20
e9/l
2.03
571
4875
342
2730
1.36
5.05
3.2
2.7
63.25
59.16
u/l
0.49
323
2544
749
6750
1.32
4.52
8.9
7.6
94.36
92.01
u/l
0.39
715
6408
38
182
2.12
4.42
3.3
3.1
17.27
16.72
%
0.65
38
176
99
639
1.60
4.41
1.7
3.1
65.73
66.54
g/l
0.42
91
603
25
100
2.53
4.37
1.7
2.4
0.77
0.98
%
1.09
15
55
395
3293
1.30
4.17
4.1
4.0
34.68
32.19
u/l
0.23
372
3143
21
79
2.68
4.14
50.1
51.3
7.47
6.45
ug/l
1.14
21
73
165
1208
1.42
4.03
5.5
5.3
9.45
7.06
umol/l
0.59
151
1028
155
1125
1.43
3.97
1.9
1.7
1154.81
1171.44
nmol/l
0.08
113
854
578
5083
1.28
3.95
7.8
8.5
0.62
0.67
%
1.85
556
4840
38
194
1.99
3.77
2.7
2.6
—
—
—
0
0
39
203
1.95
3.68
6.0
4.5
—
—
—
0
0
594
5269
1.26
3.67
7.7
8.3
28.54
31.47
%
8.20
575
5066
585
5184
1.26
3.63
7.5
8.2
56.36
53.53
%
6.64
569
5011
578
5127
1.26
3.51
4.2
3.4
90.41
89.20
ug/l
0.06
547
4867
365
3068
1.28
3.49
2.8
3.3
2.36
2.37
mmol/l
0.98
329
2840
574
5098
1.25
3.40
7.8
8.4
2.82
3.01
%
1.25
551
4858
575
5108
1.25
3.40
7.9
8.5
8.84
8.56
%
1.59
553
4870
17
64
2.67
3.38
1.2
1.1
—
—
—
0
0
94
641
1.50
3.33
3.5
3.5
4.57
4.75
pmol/l
0.77
87
583
662
5990
1.25
3.27
10.2
11.0
3.94
3.85
e9/l
0.53
581
5129
23
104
2.23
3.14
2.1
2.5
32.52
32.28
pg
0.09
23
104
21
92
2.30
3.09
2.1
3.7
—
—
—
0
0
17
380
0.44
3.04
1.1
1.1
1.53
1.54
g/l
0.09
17
380
39
219
1.80
2.97
5.3
5.3
92.23
90.96
%
0.83
39
211
305
2554
1.26
2.94
4.7
4.1
7.40
7.39
ph
0.16
218
1784
18
388
0.45
2.94
1.1
1.2
0.90
0.89
g/l
0.02
18
388
27
135
2.02
2.89
1.9
1.6
—
—
—
0
0
14
53
2.65
2.78
4.7
2.5
—
—
—
0
0
150
1153
1.34
2.75
1.7
1.5
—
—
—
0
0
39
225
1.75
2.74
1.9
2.0
—
—
—
0
0
39
225
1.75
2.74
1.9
2.0
—
—
—
0
0
7
15
4.67
2.59
1.1
1.1
—
—
—
0
0
156
1222
1.32
2.52
2.3
1.7
—
—
—
0
0
38
225
1.71
2.46
1.9
2.0
—
—
—
0
0
38
225
1.71
2.46
1.9
2.0
—
—
—
0
0
67
954
0.68
2.44
1.3
1.3
—
—
—
0
0
96
701
1.40
2.43
2.9
2.8
0.18
0.30
e6/l
0.46
91
669
91
665
1.40
2.31
5.1
4.2
7.37
7.35
ph
1.31
65
491
70
488
1.46
2.29
1.7
2.0
—
—
—
0
0
547
4964
1.19
2.26
11.8
12.1
0.00
0.00
e9/l
0.15
434
3957
27
149
1.83
2.23
2.1
1.5
658.43
343.02
mu/l
1.10
22
123
269
2292
1.22
2.16
1.8
1.6
18.47
20.68
nmol/l
1.91
237
1973
45
290
1.57
2.14
2.8
3.9
29.60
35.23
umol/l
1.72
45
269
103
780
1.35
2.12
4.8
5.7
0.09
0.09
%
0.03
32
203
244
2067
1.23
2.07
3.9
3.3
346.82
321.17
umol/l
2.83
217
1862
315
2739
1.20
2.05
3.4
2.9
—
—
—
0
0
8
26
3.08
2.00
1.1
1.1
—
—
—
0
0
811
7665
1.20
1.98
5.1
4.4
14.85
14.58
pmol/l
2.46
758
7139
178
1464
1.25
1.98
1.5
1.4
550.97
489.46
titre
0.20
31
296
30
482
0.61
1.96
1.0
1.2
2.93
3.14
u/ml
0.03
20
337
21
112
1.89
1.95
1.4
1.3
—
—
—
0
0
105
809
1.32
1.94
6.6
6.3
79.99
67.65
ng/l
1.13
90
755
29
173
1.69
1.89
1.4
1.3
25.79
19.61
u/l
0.40
22
147
45
301
1.51
1.85
2.3
2.0
2.48
3.61
iu/l
1.11
19
126
31
485
0.63
1.82
1.0
1.2
1.48
1.11
u/ml
0.15
20
322
373
3324
1.18
1.81
2.0
2.0
—
—
—
0
0
32
494
0.64
1.78
1.0
1.2
2.39
4.92
u/ml
0.88
23
358
147
1199
1.26
1.77
2.6
3.0
4.11
5.28
e9/l
1.39
126
1088
37
551
0.66
1.75
1.1
1.2
5.91
2.95
u/ml
0.34
24
385
98
762
1.31
1.72
4.1
5.0
0.72
0.54
%
0.45
36
237
70
518
1.37
1.70
1.3
1.2
—
—
—
0
0
43
293
1.48
1.64
1.9
3.3
145.56
968.15
u/ml
0.99
34
255
7
25
2.80
1.64
2.4
2.2
806.14
1370.84
e6/l
—
7
19
5
14
3.57
1.61
2.6
2.1
—
—
—
0
0
75
969
0.75
1.57
1.7
1.8
—
—
—
0
0
28
175
1.61
1.57
7.5
5.1
8.36
7.45
pmol/l
0.29
28
175
12
57
2.11
1.54
1.1
1.1
290.40
223.35
iu/ml
0.39
12
57
5
15
3.33
1.52
1.0
1.3
—
—
—
0
0
105
842
1.27
1.48
2.4
2.1
0.00
0.03
estimate
0.78
23
194
95
754
1.28
1.46
4.8
5.4
0.24
0.12
%
0.50
31
212
15
80
1.88
1.43
1.5
1.8
—
—
—
0
0
5
16
3.12
1.43
1.6
1.3
—
—
—
0
0
99
794
1.27
1.40
4.8
5.3
1.23
0.91
%
0.42
37
252
184
1576
1.20
1.40
1.6
1.6
446.70
36350585.54
pmol/l
1.92
158
1348
0
38
0.00
1.34
0.0
1.3
—
—
—
0
0
60
453
1.34
1.33
1.4
2.4
—
—
—
0
0
41
291
1.42
1.32
1.2
1.2
—
—
—
0
0
58
437
1.34
1.31
1.5
1.8
4.99
5.69
iu/ml
0.20
12
87
143
1205
1.21
1.30
1.3
1.3
—
—
—
0
0
246
2174
1.16
1.30
3.7
3.0
5.52
6.66
e6/l
0.70
235
1952
254
2252
1.16
1.28
4.6
5.2
—
—
—
0
0
5
18
2.78
1.28
1.6
1.1
—
—
—
0
0
13
69
1.89
1.27
1.3
1.1
—
—
—
0
0
8
35
2.29
1.26
2.4
1.5
71.60
80.11
nmol/24h
—
8
35
20
313
0.63
1.25
1.1
1.1
0.02
0.86
u/ml
—
10
165
126
1054
1.22
1.24
1.1
1.2
—
—
—
0
0
181
1567
1.18
1.23
2.4
2.6
2.42
2.44
mmol/l
2.48
156
1397
655
6195
1.13
1.23
5.2
4.4
29.64
2223.85
e6/l
1.53
14
82
86
693
1.26
1.20
2.7
4.3
25.67
24.64
ug/l
0.02
69
553
79
631
1.27
1.19
4.8
4.5
1.23
1.23
mmol/l
0.06
71
546
24
355
0.67
1.17
1.1
1.1
1.70
7.61
u/ml
4.63
15
229
414
3828
1.12
1.10
5.4
4.6
34.61
87.22
e6/l
2.86
304
2554
5
21
2.38
1.08
2.6
1.5
—
—
—
0
0
37
269
1.38
1.08
5.1
4.4
8.97
11.28
umol/l
0.37
29
223
128
1482
0.84
1.05
1.6
1.9
—
—
—
0
0
906
8783
1.15
1.05
6.2
5.2
1.96
1.89
mu/l
1.20
865
8280
204
1808
1.15
1.05
3.4
3.3
1.14
0.95
e6/l
0.28
118
923
1070
10529
1.33
1.04
30.6
21.8
4.48
4.53
e12/l
2.79
1053
10222
55
428
1.30
1.04
2.5
2.1
0.07
1.62
estimate
0.47
15
155
5
22
2.27
1.03
2.2
2.1
—
—
—
0
0
23
333
0.68
1.03
1.1
1.1
5.34
10.28
u/ml
0.93
12
200
1070
10531
1.32
1.02
30.7
21.9
6.78
6.80
e9/l
0.08
1054
10218
115
975
1.20
1.02
1.3
1.4
188.05
271.04
u/ml
0.78
107
912
17
106
1.61
1.02
1.1
1.2
—
—
—
0
0
811
7814
1.13
1.01
5.8
5.6
37.81
38.19
mmol/mol
0.64
776
7419
37
273
1.36
1.00
1.8
1.9
35.10
22.70
ng/l
0.53
37
273
1069
10523
1.31
0.99
30.7
21.9
250.15
261.63
e9/l
6.86
1057
10252
323
2963
1.12
0.98
1.5
1.7
1.95
1.99
g/l
0.22
210
1700
0
30
0.00
0.97
0.0
2.0
—
—
—
0
0
59
731
0.79
0.96
1.6
1.6
1199.48
1000.61
mu/l
0.67
48
641
840
8119
1.13
0.96
4.9
4.4
5.72
5.76
mmol/l
0.35
789
7534
217
1945
1.14
0.95
4.1
3.1
567.53
544.71
mosm/kgh2o
0.73
204
1706
15
93
1.62
0.93
4.4
4.1
0.80
0.65
index
0.32
15
93
387
3597
1.11
0.92
2.3
2.0
95.86
97.34
pmol/l
0.26
233
1873
25
176
1.43
0.89
6.1
4.0
—
—
—
0
0
8
44
1.82
0.85
1.4
1.3
—
—
—
0
0
8
44
1.82
0.85
1.4
1.3
—
—
—
0
0
8
44
1.82
0.85
1.4
1.3
—
—
—
0
0
360
3348
1.11
0.84
7.4
7.5
—
—
—
0
0
292
2686
1.11
0.84
4.2
3.9
0.00
0.01
estimate
1.23
94
968
259
2370
1.12
0.82
4.2
4.2
7.15
15.63
mg/mmol
0.57
174
1501
100
857
1.18
0.82
1.3
1.3
136.81
138.22
u/ml
0.01
36
315
36
276
1.31
0.79
3.1
3.2
3.87
3.48
index
0.12
24
162
255
2337
1.11
0.79
3.6
3.5
41.19
51.29
mg/l
0.44
172
1536
6
33
1.82
0.79
2.0
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
2.4
—
40.12
—
0
26
0
26
0.00
0.78
0.0
4.8
—
7.62
—
0
26
29
216
1.35
0.78
1.6
1.4
81.16
174.66
pmol/l
0.89
29
209
56
677
0.81
0.77
1.9
1.7
—
—
—
0
0
348
3246
1.10
0.76
4.6
3.8
56.03
61.01
e6/l
0.06
288
2421
6
34
1.76
0.76
2.7
2.5
31.50
29.00
%
—
6
34
42
334
1.26
0.72
1.5
1.2
—
—
—
0
0
9
58
1.55
0.69
2.0
2.5
—
—
—
0
0
15
215
0.69
0.69
1.0
1.5
1.83
3.67
u/ml
—
9
143
12
77
1.56
0.68
1.7
1.4
1.40
1.37
promille
0.03
12
63
25
187
1.34
0.67
2.0
1.6
24932.44
15136.07
e6/l
0.52
18
135
442
4190
1.08
0.66
3.7
3.5
6.29
6.23
ph
0.43
221
2276
49
402
1.22
0.66
2.5
2.5
—
—
—
0
0
32
250
1.28
0.65
16.2
8.2
—
—
—
0
0
5
29
1.72
0.63
1.0
1.7
—
—
—
0
0
36
445
0.80
0.63
1.4
1.3
166.89
227.79
miu/ml
0.89
18
212
15
104
1.44
0.61
1.3
2.2
—
—
—
0
0
5
30
1.66
0.61
1.0
1.3
—
—
—
0
0
37
451
0.81
0.58
1.2
1.1
—
—
—
0
0
7
112
0.62
0.58
1.1
1.3
6.52
5.87
u/ml
—
7
107
15
207
0.72
0.58
1.1
1.6
10.48
13.49
u/ml
—
6
130
10
64
1.56
0.58
3.8
2.9
—
—
—
0
0
37
300
1.24
0.57
1.6
1.4
284.64
315.21
ug/g
0.42
22
174
27
211
1.28
0.56
1.5
2.7
73.95
74.98
mmol/l
0.04
22
188
8
55
1.45
0.56
5.5
4.0
119.65
135.57
ug/l
—
8
55
6
38
1.58
0.54
1.3
1.3
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
185.17
174.44
mmol/24h
—
6
38
33
402
0.81
0.53
1.5
1.5
77.40
62.00
ug/l
0.90
27
348
188
1735
1.10
0.53
3.8
3.5
3.69
2.53
e6/l
0.69
104
856
12
169
0.70
0.53
1.0
1.2
1.18
2.57
u/ml
—
5
99
23
178
1.29
0.52
1.1
1.1
—
—
—
0
0
51
433
1.18
0.51
5.5
6.5
256.29
345.19
mg/l
0.60
38
271
12
83
1.45
0.51
1.5
3.8
61.33
55.31
%
0.46
12
75
317
3002
1.07
0.48
3.8
3.9
7.70
7.91
mmol/l
0.33
276
2644
303
2866
1.07
0.48
4.4
3.7
0.41
0.34
e6/l
0.30
243
2051
20
154
1.30
0.47
1.1
1.1
1.48
1.44
g/l
0.18
20
144
129
1177
1.10
0.47
3.8
2.6
345.21
357.68
nmol/l
0.24
121
1117
17
128
1.33
0.47
1.1
1.8
—
—
—
0
0
107
967
1.11
0.47
1.7
1.4
—
—
—
0
0
534
5153
1.06
0.46
4.4
3.8
11.70
3.05
estimate
0.33
103
1026
23
183
1.26
0.44
3.7
3.7
4.97
3.90
e9/l
1.00
23
183
878
8614
1.07
0.43
24.4
18.6
13.56
13.41
%
2.94
871
8531
5
31
1.61
0.43
1.2
1.3
—
—
—
0
0
8
56
1.43
0.42
1.3
1.4
78.63
71.09
umol/l
—
8
56
0
15
0.00
0.41
0.0
12.4
—
96.13
—
0
15
342
3267
1.06
0.40
1.5
1.6
0.71
2.76
u/ml
6.68
84
762
262
2744
0.94
0.40
4.1
3.2
0.65
0.01
estimate
0.52
81
836
5
34
1.47
0.40
3.4
2.5
536.00
522.00
min
—
5
24
66
736
0.89
0.40
2.4
2.2
6.02
6.17
ph
0.73
44
482
15
114
1.32
0.40
4.9
3.8
14.33
15.89
index
0.23
15
93
0
18
0.00
0.40
0.0
1.5
—
68.17
—
0
18
17
132
1.29
0.39
1.6
1.4
—
—
—
0
0
5
35
1.43
0.39
2.0
1.9
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
4.57
5.64
mg/g
—
5
35
63
703
0.89
0.39
1.8
1.9
—
—
—
0
0
59
661
0.88
0.39
1.7
1.9
—
—
—
0
0
10
71
1.41
0.38
1.1
1.2
—
—
—
0
0
25
299
0.83
0.37
1.9
3.0
32.10
240.90
e6/l
1.91
20
222
17
212
0.80
0.36
1.0
1.0
-2.95
-2.07
mmol/l
—
6
51
17
212
0.80
0.36
1.0
1.0
—
—
—
0
0
25
298
0.83
0.36
1.9
3.0
1.32
7.82
e6/l
1.84
19
214
25
298
0.83
0.36
1.6
1.5
—
—
—
0
0
6
41
1.46
0.36
1.0
1.0
—
—
—
0
0
637
6209
1.05
0.36
4.3
3.9
54.05
41.21
u/l
1.98
614
5931
6
42
1.43
0.35
1.3
2.2
94.58
107.10
ng/l
—
6
42
6
42
1.43
0.35
1.2
1.3
—
—
—
0
0
14
178
0.78
0.35
1.0
1.1
7.08
14.18
u/ml
—
6
49
43
488
0.87
0.35
2.6
2.2
—
—
—
0
0
80
726
1.11
0.35
1.4
1.6
—
—
—
0
0
10
73
1.37
0.34
1.4
1.2
—
—
—
0
0
18
219
0.82
0.32
1.5
1.3
—
—
—
0
0
17
208
0.81
0.32
1.1
1.1
—
—
—
0
0
848
8339
1.06
0.32
5.0
4.6
4.42
4.64
mmol/l
8.93
813
7903
15
186
0.80
0.31
2.3
3.9
—
—
—
0
0
26
304
0.85
0.31
1.7
1.5
—
—
—
0
0
13
101
1.29
0.31
1.2
1.1
—
—
—
0
0
13
101
1.29
0.31
1.5
3.9
—
—
—
0
0
14
110
1.27
0.31
1.2
1.2
—
—
—
0
0
797
7829
1.05
0.30
4.4
3.9
1.20
1.25
mmol/l
1.12
757
7347
264
2527
1.05
0.30
3.9
3.7
—
0.18
—
0
17
123
1303
0.93
0.28
1.3
1.2
—
—
—
0
0
30
260
1.15
0.28
1.1
1.2
—
—
—
0
0
55
497
1.11
0.28
1.7
1.7
—
—
—
0
0
524
5107
1.04
0.28
4.4
3.8
0.00
0.00
estimate
0.50
100
1016
20
236
0.84
0.27
1.0
1.1
2.05
4.84
eliau/ml
0.86
11
90
8
64
1.25
0.27
1.0
2.1
6.56
3.08
nmol/l
—
8
64
25
287
0.86
0.25
1.6
1.5
1.30
1.27
mm
0.09
18
211
374
3627
1.04
0.25
1.8
1.9
1.31
1.34
mmol/l
0.25
321
3182
16
132
1.21
0.25
2.6
4.0
221.18
2073.48
u/ml
0.52
16
127
25
286
0.87
0.25
1.1
1.3
—
—
—
0
0
10
126
0.79
0.25
2.2
1.4
372.10
449.39
pmol/l
—
10
109
14
169
0.82
0.24
1.5
1.7
—
—
—
0
0
39
349
1.12
0.24
2.2
2.0
—
—
—
0
0
65
700
0.92
0.24
1.7
1.9
—
—
—
0
0
286
2762
1.04
0.23
4.4
3.6
—
1.75
estimate
—
0
8
52
565
0.91
0.23
1.8
1.8
—
—
—
0
0
851
8394
1.04
0.23
5.5
5.1
2.60
2.74
mmol/l
5.49
813
7926
25
284
0.87
0.23
1.7
3.0
—
—
—
0
0
5
39
1.28
0.23
3.4
2.6
743.00
607.88
ml
—
5
25
86
913
0.93
0.22
2.7
2.9
0.82
0.70
ug/l
0.22
54
512
190
1968
0.95
0.22
1.7
1.7
—
—
—
0
0
38
342
1.11
0.22
1.2
1.1
18.62
15.57
au/ml
—
5
62
24
272
0.88
0.21
4.3
2.0
0.75
0.73
nmol/l
0.08
17
234
66
706
0.93
0.21
1.8
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
5
42
1.19
0.21
1.4
2.5
13.24
20.05
umol/l
—
5
42
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
58.67
—
0
12
0
12
0.00
0.21
0.0
3.4
—
0.43
—
0
12
18
154
1.17
0.20
6.4
4.0
1.68
1.66
umol/l
0.04
18
149
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
17
145
1.17
0.20
1.5
1.3
—
—
—
0
0
14
117
1.19
0.20
1.2
1.2
—
—
—
0
0
12
143
0.83
0.19
1.0
1.3
3.93
24.00
u/ml
—
6
115
66
702
0.93
0.19
1.7
1.9
—
—
—
0
0
182
1751
1.04
0.18
1.5
1.3
14.60
28.54
iu/ml
5.66
51
492
10
81
1.23
0.18
1.2
1.1
—
—
—
0
0
16
137
1.17
0.18
1.3
1.3
—
—
—
0
0
7
59
1.18
0.18
1.1
1.2
20.43
8.05
mm/h
—
7
59
18
205
0.87
0.18
1.6
3.8
53.44
42.69
mg/l
0.38
13
173
18
205
0.87
0.18
1.6
3.8
37.20
54.11
mg/l
0.47
13
172
7
61
1.14
0.17
1.0
1.2
—
—
—
0
0
74
697
1.06
0.17
2.2
2.4
10.62
16.97
au/ml
—
6
65
232
2376
0.97
0.17
2.0
2.1
—
—
—
0
0
528
5185
1.03
0.17
4.5
3.9
0.00
0.01
estimate
0.97
95
980
8
71
1.12
0.16
1.0
1.1
—
—
—
0
0
51
475
1.07
0.16
1.0
1.1
—
—
—
0
0
78
817
0.95
0.15
1.7
1.7
3.33
3.47
mmol/l
0.46
57
567
15
130
1.15
0.15
1.5
1.9
—
2413.33
—
0
6
33
356
0.92
0.14
1.6
1.7
28.74
7.49
u/ml
—
5
86
370
3748
0.98
0.13
4.2
3.6
6.61
0.02
estimate
0.49
76
846
11
127
0.86
0.13
2.0
1.6
—
—
—
0
0
11
94
1.17
0.12
1.1
1.2
100.45
114.30
pmol/l
0.44
11
94
15
168
0.89
0.12
2.1
2.9
—
—
—
0
0
837
8290
1.02
0.12
5.0
4.5
1.43
1.47
mmol/l
2.38
799
7816
177
1721
1.03
0.11
2.0
3.1
115.97
101.66
ug/g
0.27
133
1402
80
766
1.04
0.11
2.2
2.3
8.90
11.65
nmol/l
2.05
71
714
64
667
0.95
0.11
1.2
1.2
—
—
—
0
0
96
924
1.04
0.11
2.7
2.4
34.89
35.15
u/l
0.02
85
758
14
124
1.13
0.10
1.8
2.2
—
—
—
0
0
38
401
0.94
0.10
1.8
1.9
285.76
193.52
u/ml
0.89
25
195
36
338
1.06
0.10
1.3
1.2
—
—
—
0
0
19
173
1.10
0.10
1.0
1.1
—
—
—
0
0
47
446
1.05
0.09
1.7
1.6
0.27
0.30
mg/l
0.12
17
195
342
3452
0.98
0.09
2.8
2.8
—
—
—
0
0
14
154
0.90
0.08
1.1
1.1
—
—
—
0
0
11
97
1.13
0.08
1.0
1.3
—
—
—
0
0
24
223
1.07
0.08
1.2
1.2
—
—
—
0
0
980
9736
1.03
0.08
13.5
11.5
25.01
25.76
u/l
0.66
963
9506
5
65
0.77
0.08
2.8
1.6
5.38
6.11
mmol/l
—
5
48
448
4505
0.98
0.08
3.4
3.1
75.74
74.08
nmol/l
0.62
410
4172
17
184
0.92
0.08
1.6
3.7
1.51
2.01
ratio
—
9
108
76
781
0.97
0.08
1.9
1.8
16.94
19.68
iu/l
0.40
61
592
6
73
0.82
0.07
1.0
1.1
31.17
38.70
iu/ml
—
6
73
133
1353
0.98
0.07
1.6
1.6
—
—
—
0
0
35
332
1.05
0.07
2.2
2.1
102.47
117.01
au/ml
0.39
15
129
8
90
0.88
0.06
2.5
1.9
119.38
126.77
ng/l
—
8
81
8
93
0.86
0.06
1.1
1.0
—
—
—
0
0
16
147
1.09
0.06
1.8
4.9
—
—
—
0
0
25
235
1.06
0.06
2.0
1.5
0.65
0.36
nmol/l
0.29
18
186
101
984
1.03
0.06
1.5
1.4
—
—
—
0
0
166
1628
1.02
0.06
1.3
1.3
8.06
9.65
u/ml
0.12
60
612
9
101
0.89
0.06
1.2
1.3
—
—
—
0
0
11
99
1.11
0.06
1.0
1.0
164.27
162.54
g/l
0.11
11
99
45
433
1.04
0.05
1.4
1.3
—
—
—
0
0
11
100
1.10
0.05
2.0
1.8
—
—
—
0
0
11
100
1.10
0.05
1.2
1.1
183.00
223.37
mg/l
0.65
11
90
66
643
1.02
0.04
2.1
2.3
12038.44
5035.09
u/l
0.64
21
242
77
753
1.02
0.04
5.0
3.8
—
—
—
0
0
14
149
0.94
0.04
1.1
1.3
—
—
—
0
0
24
229
1.05
0.03
4.3
3.9
1.31
1.37
mmol/l
0.17
24
222
12
111
1.08
0.03
1.0
1.1
—
—
—
0
0
88
866
1.01
0.02
1.5
1.5
—
—
—
0
0
152
1526
0.99
0.02
4.7
4.5
1.61
2.11
ug/l
1.03
133
1402
33
321
1.03
0.01
1.2
1.2
—
—
—
0
0
233
2311
1.01
0.01
4.2
3.7
1.02
1.02
kg/l
0.31
145
1525
33
322
1.02
0.01
1.2
1.2
—
—
—
0
0
22
225
0.97
0.00
1.1
1.7
0.34
0.72
g/l
3.29
17
187
13
134
0.97
0.00
1.2
1.5
—
—
—
0
0
38
377
1.00
0.00
1.8
1.9
—
—
—
0
0
33
331
0.99
0.00
2.2
2.1
—
—
—
0
0
64
637
1.00
0.00
1.2
1.3
15.28
40.94
au/ml
—
5
37
32
315
1.01
0.00
3.7
3.0
59.02
54.59
%
0.87
32
315
58
578
1.00
0.00
2.1
2.0
8.86
7.76
u/l
0.29
35
375
108
1077
1.00
0.00
1.9
1.9
3.49
3.50
ratio
0.02
86
819
20
198
1.01
0.00
1.1
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
395.89
—
0
8
0
8
0.00
0.00
0.0
1.1
—
308.13
—
0
8
0
8
0.00
0.00
0.0
1.0
—
12.88
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
4.4
—
7.80
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.1
1260.00
1350.52
miu/ml
—
5
58
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
217.00
—
0
5
5
52
0.96
-0.00
3.0
3.0
731.00
987.46
mg
—
5
52
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
59
1.01
-0.00
1.3
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
179.29
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
399.71
—
0
7
9
91
0.99
-0.00
2.0
2.1
—
—
—
0
0
6
62
0.96
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
7
69
1.01
-0.00
3.1
3.2
608.57
822.16
u/ml
—
7
69
0
7
0.00
-0.00
0.0
1.3
—
35.29
—
0
7
6
63
0.95
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
64
0.93
-0.00
2.8
3.5
47.70
15.72
mg/l
—
6
43
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_ATRIAL_SEPTAL_DEFECT_SECUNDUM_TYPE – Atrial septal defect, secundum type

GWS hits: 2

This endpoint is excluded (different definition than used in FinnGen).