Convergent concomitant strabismus

H7_CONVERSTRAB

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H50.0
  • Hospital discharge: ICD-9 3780
  • Hospital discharge: ICD-8 37300
  • Cause of death: ICD-10 H50.0
  • Cause of death: ICD-9 3780
  • Cause of death: ICD-8 37300

2 out of 7 registries used, show all original rules.

2719

4. Check minimum number of events

None

2719

5. Include endpoints

None

2719

6. Filter based on genotype QC (FinnGen only)

2432

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H50
Name in latin
Strabismus convergens concomitans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31953 16397 15488
Only index persons 27242 14182 13060
Unadjusted period prevalence (%)
Whole population 0.45 0.47 0.43
Only index persons 0.51 0.52 0.50
Median age at first event (years)
Whole population 6.21 6.47 5.83
Only index persons 6.67 7.01 6.31

-FinnGen-

Key figures

All Female Male
Number of individuals 2432 1561 871
Unadjusted period prevalence (%) 0.50 0.55 0.40
Median age at first event (years) 10.53 10.94 9.79

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2539
Matched controls
25390
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
3985.1
307.7
356
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
43.7
307.7
220
55
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
307.7
1074
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
16384.0
307.7
1263
*
H50.30
ICD-10 Finland
Intermittent esotropy
1634.3
301.0
287
*
H52.0
ICD-10 Finland
Hypermetropia
23.1
278.5
205
96
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
248.1
234
*
3503
FHL
Single muscle retroposition
+∞
229.7
217
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
2049.4
209.2
200
*
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
198.6
188
*
H53.2
ICD-10 Finland
Diplopia
11.1
191.2
210
205
H50.1
ICD-10 Finland
Divergent concomitant strabismus
920.5
177.4
172
*
H50.2
ICD-10 Finland
Vertical strabismus
287.0
159.5
161
6
H50.31
ICD-10 Finland
Intermittent exotropia
611.0
119.1
117
*
3507
FHL
Retroposition and resection
1203.0
118.8
115
*
H50.51
ICD-10 Finland
Esophoria
158.7
115.3
121
8
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
518.0
101.3
100
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
98.6
94
*
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
26.4
96.9
67
26
H50.52
ICD-10 Finland
Exophoria
23.0
86.6
63
28
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
82.8
79
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
803.0
79.8
78
*
H52.1
ICD-10 Finland
Myopia
6.1
76.0
136
234
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
75.4
72
*
3504
FHL
Retroposition of two muscles
+∞
74.3
71
*
H52.2
ICD-10 Finland
Astigmatism
10.0
72.7
84
87
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.3
71.1
298
989
H50.9
ICD-10 Finland
Strabismus, unspecified
99.3
70.3
77
8
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
63.8
61
*
3505
FHL
Single muscle resection
+∞
58.6
56
*
H50.8
ICD-10 Finland
Other specified strabismus
197.8
56.2
58
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
14.5
52.0
47
33
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
50.2
492
2472
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
+∞
49.1
47
*
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
47.0
45
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
43.9
42
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
11.8
41.2
42
36
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
10.7
37.6
41
39
WX140
NOMESCO Finland
Parabulbar anesthesy
3.8
36.8
116
318
F83
ICD-10 Finland
Mixed specific developmental disorders
7.4
35.6
52
72
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
352.0
35.0
35
*
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
34.4
33
*
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
34.4
33
*
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
34.4
33
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
31.7
892
6188
XCK00
NOMESCO Finland
Perimetry
3.1
29.6
129
434
3510
FHL
Cardiac surgery on three or more muscles
+∞
29.2
28
*
37929
ICD-8 Finland
Blindness, one eye, specifically defined
66.8
28.9
33
5
3508
FHL
Transposition or anteposition
+∞
28.2
27
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
28.2
27
*
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
25.0
24
*
F95
ICPC
Strabismus
43.3
24.6
30
7
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.3
23.5
193
889
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
22.9
22
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
22.5
608
4108
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
17.2
21.8
34
20
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
21.7
280
1527
H50.4
ICD-10 Finland
Other and unspecified heterotropia
221.8
21.6
22
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
20.2
582
3980
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
19.8
19
*
ZXA05
NOMESCO Finland
Left side
1.7
19.7
451
2910
P85
ICPC
Mental retardation
16.0
18.8
30
19
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
18.8
18
*
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
18.8
18
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.8
18.3
94
347
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
25.2
18.2
25
10
3780X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALIUS]
+∞
17.7
17
*
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
17.7
17
*
CE2W4
NOMESCO Finland
Eye movement mapping
24.2
17.3
24
10
R62.0
ICD-10 Finland
Delayed milestone
4.6
17.3
41
91
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
17.0
213
1148
ZXA10
NOMESCO Finland
Bilateral
1.7
17.0
362
2288
37309
ICD-8 Finland
Strabismus, Unspecified
+∞
16.7
16
*
H50
ICD-10 Finland
Other strabismus
171.1
16.5
17
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
16.2
187
980
F82
ICD-10 Finland
Specific developmental disorder of motor function
5.2
15.8
32
62
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
15.6
15
*
3519
FHL
Other measure in this category
+∞
15.6
15
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.2
15.4
126
579
ZXA00
NOMESCO Finland
Right side
1.5
15.1
467
3224
3670A
ICD-9 Finland
Disorders of refraction and accommodation, Hypermetropia
+∞
14.6
14
*
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
14.6
14
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
12.0
14.1
25
21
S01FA01
ATC
atropine; ophthalmic
12.7
13.9
24
19
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
13.6
152
788
H50.3
ICD-10 Finland
Intermittent heterotropia
+∞
13.6
13
*
3501
FHL
Myotomy or tenotomy
+∞
13.6
13
*
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
13.6
13
*
H54.5
ICD-10 Finland
Severe visual impairment, monocular
10.1
13.0
25
25
H52.4
ICD-10 Finland
Presbyopia
2.6
12.7
74
292
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
4.8
12.6
28
59
WX402
NOMESCO Finland
General anaesthesia
1.5
12.6
528
3867
Z3231
NOMESCO Finland
Registered nurse
1.4
12.4
574
4283
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.2
12.3
48
152
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.2
12.3
104
486
WX002
NOMESCO Finland
Sedation and analgesia
1.6
12.3
349
2357
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
12.2
165
913
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
18.1
12.0
18
10
H26.4
ICD-10 Finland
After-cataract
2.0
11.9
125
634
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
11.9
182
1045
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
11.9
347
2355
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
11.5
11
*
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
120.5
11.4
12
*
H53.4
ICD-10 Finland
Visual field defects
3.2
11.4
45
144
CS494
NOMESCO Finland
Other visual field testing
3.0
11.4
49
165
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
11.3
430
3083
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
11.2
433
3116
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
11.1
691
5408
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
11.1
164
932
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
28.1
10.7
14
5
Q12.0
ICD-10 Finland
Congenital cataract
28.1
10.7
14
5
34301
ICD-8 Finland
Cerebral spastic infantile paralysis, Diplegia spastica
60.3
10.6
12
*
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
110.5
10.4
11
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
110.5
10.4
11
*
3782A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS CONVERGENS INTERMITTENS]
+∞
10.4
10
*
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
10.4
10
*
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
10.4
10
*
3768
FHL
Eye examination under general anesthesia
32.7
10.3
13
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.9
10.3
121
639
ZXD20
NOMESCO Finland
Day surgery
1.6
10.1
264
1746
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
10.1
1798
16337
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.3
10.0
36
109
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.9
9.9
114
598
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
9.9
299
2044
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
2.3
9.6
71
314
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
9.5
105
543
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.2
9.4
74
336
3430A
ICD-9 Finland
Infantile cerebral palsy, Diplegic
30.1
9.4
12
*
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
9.4
9
*
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
9.4
9
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
3.5
9.3
31
89
AA1AD
NOMESCO Finland
CT of head and brain
1.4
9.2
459
3449
TAB00
NOMESCO Finland
Lumbar puncture
1.9
9.2
106
558
CAC44
NOMESCO Finland
Combined decompression of orbit
36.8
9.0
11
*
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
7.0
9.0
21
30
N03AG01
ATC
valproic acid; systemic, rectal
1.8
8.9
135
774
N03AX14
ATC
levetiracetam; systemic
2.3
8.7
61
264
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
14.1
8.7
14
10
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
8.5
121
681
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.1
8.5
23
57
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.6
8.5
49
194
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
8.4
726
5926
XCW11
NOMESCO Finland
Assessment of strabismus
90.4
8.4
9
*
H50.39
ICD-10 Finland
Intermittent heterotropia
90.4
8.4
9
*
H54.7
ICD-10 Finland
Unspecified visual loss
4.3
8.4
21
49
ZXE00
NOMESCO Finland
One hour or less
1.3
8.3
815
6768
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.6
8.3
203
1324
H52.5
ICD-10 Finland
Disorders of accommodation
33.5
8.1
10
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
8.0
190
1228
H26.02
ICD-10 Finland
Presenil cataract
2.4
8.0
52
218
S01CA03
ATC
hydrocortisone and antiinfectives; ophthalmic
3.6
8.0
25
69
WX704
NOMESCO Finland
Intubation
1.6
7.9
166
1043
R52.9
ICD-10 Finland
Pain, unspecified
1.5
7.9
219
1469
N05BA09
ATC
clobazam; oral
3.6
7.8
25
70
H47.2
ICD-10 Finland
Optic atrophy
8.5
7.8
16
19
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.7
409
3099
WX702
NOMESCO Finland
Supraglottic ventilation device
1.8
7.7
119
687
CD2S4
NOMESCO Finland
Photography of eye
5.9
7.7
20
34
XA800
NOMESCO Finland
Neuropsychological investigation
1.9
7.6
97
528
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
18.4
7.6
11
6
183
Kela drug reimbursment
Lamotrigin and topiramate
3.3
7.4
27
83
3795A
ICD-9 Finland
Other disorders of eye, Nystagmus and other irregular eye movements
+∞
7.3
7
*
H53.3
ICD-10 Finland
Other disorders of binocular vision
4.3
7.2
18
42
WX882
NOMESCO Finland
High dependency care
2.1
7.2
65
314
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.2
7.2
58
268
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
12.0
7.1
12
10
N06AX21
ATC
duloxetine; oral
1.5
7.0
255
1806
H03AA01
ATC
levothyroxine sodium; systemic
1.3
7.0
439
3411
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
7.0
273
1959
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
10.0
7.0
13
13
WX725
NOMESCO Finland
Noninvasive ventilation
1.7
7.0
112
654
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
7.0
161
1035
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
7.0
138
854
S01FA04
ATC
cyclopentolate; ophthalmic
3.3
7.0
25
76
M41.4
ICD-10 Finland
Neuromuscular scoliosis
11.0
6.8
12
11
F79
ICD-10 Finland
Unspecified mental retardation
40.2
6.8
8
*
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
3.6
6.7
21
58
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.9
6.7
79
420
N03AX12
ATC
[U] gabapentin; oral
1.4
6.7
283
2064
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
2.7
6.6
33
122
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
6.6
456
3598
A28
ICPC
Limited function/disability NOS
1.5
6.6
224
1569
N03AX16
ATC
[U] pregabalin
1.3
6.5
402
3121
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
6.4
249
1789
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
6.4
136
859
S01EA03
ATC
apraclonidine; ophthalmic
3.7
6.4
19
51
S01ED01
ATC
timolol; ophthalmic
2.3
6.3
43
185
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
6.3
511
4117
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
3.8
6.3
18
47
3785A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Paralytic strabismus
+∞
6.3
6
*
3431A
ICD-9 Finland
Infantile cerebral palsy, Hemiplegic
+∞
6.3
6
*
3699X
ICD-9 Finland
Blindness and low vision, Unspecified visual loss
+∞
6.3
6
*
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
6.3
6
*
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
26.7
6.2
8
*
H16.0
ICD-10 Finland
Corneal ulcer
1.7
6.2
110
663
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.4
6.2
263
1920
H25.1
ICD-10 Finland
Senile nuclear cataract
1.4
6.2
269
1972
N03AF02
ATC
oxcarbazepine; oral
1.9
6.1
68
355
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.3
6.1
45
201
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.4
6.0
38
158
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
6.0
413
3251

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
46
118
3.95
16.11
1.1
1.1
0.12
4.14
nmol/l
—
7
20
1046
8490
1.39
14.34
5.5
5.1
37.03
36.76
g/l
0.86
986
8011
63
217
2.95
14.00
1.7
1.6
—
—
—
0
0
126
612
2.11
13.46
1.3
1.8
439.95
490.86
mg/l
0.96
119
588
109
515
2.17
12.51
1.5
2.0
—
—
—
0
0
51
167
3.10
12.40
1.1
1.3
1.87
1.87
mmol/l
0.01
46
155
110
554
2.03
10.72
1.2
1.7
3.64
3.64
mmol/l
0.01
102
527
1356
11820
1.32
10.31
6.2
5.0
6.34
6.46
mmol/l
1.51
1270
11017
1123
9552
1.31
10.13
9.1
7.2
1.21
1.21
mmol/l
0.06
1011
8352
107
550
1.99
9.88
1.5
1.9
23.03
19.10
e6/l
0.16
79
404
108
557
1.98
9.87
1.5
1.9
2190.49
1262.18
e6/l
0.23
83
432
1010
8496
1.31
9.76
8.7
6.8
1.21
1.21
mmol/l
0.39
956
7939
610
4785
1.36
9.46
4.5
4.2
—
—
—
0
0
50
204
2.48
8.15
1.1
1.1
222.22
239.84
mg/l
0.31
45
176
271
1890
1.49
8.10
11.6
9.3
7.41
7.41
ph
0.04
145
1032
51
212
2.43
8.00
1.2
1.2
33.24
37.83
mg/l
0.46
42
174
270
1890
1.48
7.92
11.6
9.2
5.12
5.13
kpa
0.04
256
1817
270
1890
1.48
7.92
11.6
9.2
13.64
12.98
kpa
0.95
257
1818
267
1867
1.48
7.87
11.7
9.3
1.01
0.84
mmol/l
0.28
210
1537
1178
10322
1.26
7.63
6.6
6.3
11.19
11.39
umol/l
0.14
1113
9855
153
962
1.63
7.27
12.8
11.8
16.18
16.19
%
0.02
147
927
899
7660
1.27
7.26
3.8
3.3
30.63
30.74
u/l
0.03
862
7291
228
1571
1.50
7.23
12.9
10.1
120.70
123.07
g/l
0.91
221
1536
1699
15594
1.27
7.22
8.5
7.7
78.15
77.62
u/l
0.20
1625
14887
240
1676
1.48
7.12
12.4
9.8
96.08
96.09
%
0.00
231
1621
42
171
2.48
6.93
1.3
1.2
0.58
0.59
ratio
0.06
29
98
142
890
1.63
6.84
3.1
3.0
21.12
20.88
s
0.25
126
795
682
5658
1.28
6.76
3.3
2.6
—
—
—
0
0
925
7987
1.25
6.48
12.1
10.5
1.18
1.16
inr
0.58
773
6605
673
5599
1.27
6.48
2.3
2.2
168.40
237.06
u/l
1.42
638
5357
629
5198
1.28
6.38
5.0
4.3
91.79
93.24
%
0.83
614
5100
1294
11603
1.23
6.36
4.0
3.5
0.00
0.14
estimate
0.53
223
2220
1289
11555
1.23
6.35
3.9
3.5
0.00
6.68
estimate
2.77
230
2343
1502
13687
1.24
6.34
4.9
4.1
1330.55
2128.43
e6/l
0.31
22
159
1879
17575
1.27
6.19
5.2
4.4
14.58
14.50
pmol/l
0.78
1772
16496
1276
11445
1.23
6.19
3.9
3.5
0.00
0.00
estimate
0.80
228
2327
248
1793
1.42
6.14
11.2
10.2
—
—
—
0
0
114
696
1.67
6.12
3.6
2.1
6.64
3.67
iu/l
1.80
62
302
782
6669
1.25
6.02
3.2
3.3
2.35
2.35
mmol/l
0.35
730
6181
199
1400
1.46
5.71
4.4
4.2
71.21
77.36
ng/l
0.59
185
1262
1056
9345
1.22
5.66
3.5
3.1
6.27
6.22
ph
0.75
573
5399
252
1855
1.40
5.64
3.2
2.6
0.22
0.22
g/l
0.30
239
1747
272
2042
1.37
5.41
5.6
5.1
7.37
7.38
ph
0.57
169
1201
334
2591
1.33
5.36
7.6
6.7
1.08
1.08
mmol/l
0.00
314
2427
1102
9843
1.21
5.25
2.9
2.7
—
—
estimate
—
0
0
657
5566
1.24
5.25
4.2
3.9
7.40
7.40
ph
0.01
470
3903
263
1975
1.37
5.22
5.7
5.1
1.92
1.70
mmol/l
0.57
241
1688
1506
13879
1.21
5.11
3.7
3.4
0.50
17914.78
—
6
23
142
957
1.51
5.07
1.6
2.1
11.90
7.13
iu/ml
0.41
24
230
397
3181
1.29
5.04
5.2
4.2
0.81
0.82
mmol/l
1.67
374
3042
104
654
1.62
5.03
8.1
5.4
0.88
0.90
%
0.19
97
616
2212
21282
1.31
4.79
17.7
14.0
139.68
139.62
mmol/l
0.56
2170
20854
74
431
1.74
4.79
3.3
3.2
36.42
33.32
umol/l
0.63
69
402
53
280
1.91
4.69
1.9
2.7
—
—
—
0
0
1292
11794
1.19
4.67
8.0
6.9
1.95
2.01
e9/l
1.12
1164
10519
161
1133
1.45
4.66
3.2
3.1
190.79
155.16
ng/l
0.29
139
1011
1204
10925
1.19
4.64
7.7
6.9
29.44
29.67
%
0.30
1148
10447
255
1942
1.35
4.64
3.1
3.3
1.68
1.74
%
0.38
227
1768
1164
10533
1.19
4.62
7.8
7.0
2.81
2.84
%
0.13
1105
9953
1187
10765
1.19
4.58
7.7
6.8
55.73
55.88
%
0.18
1140
10349
2214
21332
1.30
4.53
17.8
14.1
3.94
3.94
mmol/l
0.35
2169
20849
326
2593
1.30
4.37
1.8
1.7
1143.46
1164.62
nmol/l
0.17
254
2013
769
6728
1.21
4.35
2.6
2.3
—
—
—
0
0
1258
11500
1.19
4.35
8.1
6.9
0.04
0.04
e9/l
0.32
1100
9986
1257
11492
1.19
4.34
8.1
6.8
0.56
0.56
e9/l
0.09
1099
9986
348
2795
1.28
4.33
2.1
2.0
—
—
—
0
0
144
1009
1.45
4.29
13.5
12.0
24.55
24.18
mmol/l
0.86
139
992
1161
10553
1.18
4.26
7.9
7.1
8.63
8.53
%
0.64
1100
9986
205
1532
1.37
4.23
4.2
3.5
4.38
4.63
pmol/l
3.86
193
1380
2112
20269
1.25
4.22
6.2
5.2
1.75
1.81
mu/l
1.79
2016
19232
83
518
1.62
4.19
9.4
6.0
1.36
1.27
mmol/l
0.23
73
452
92
589
1.58
4.19
3.5
2.5
224.26
329.93
ug/l
0.59
87
551
108
722
1.52
4.07
7.9
5.1
1.82
1.60
%
1.11
100
681
413
3411
1.25
4.07
1.4
1.4
475.00
520.29
titre
0.19
80
678
1155
10521
1.18
4.06
7.9
7.1
0.68
0.68
%
0.03
1092
9927
221
1683
1.34
4.04
11.6
9.2
1.31
1.34
mmol/l
0.19
216
1647
288
2277
1.30
4.04
2.7
2.2
365.51
377.71
nmol/l
0.52
270
2136
421
3490
1.25
4.01
2.8
2.7
2.42
2.43
mmol/l
1.87
369
3126
103
688
1.52
3.91
2.3
2.0
1.40
1.42
g/l
0.09
87
616
728
6394
1.19
3.88
3.1
2.6
55.63
58.16
u/l
0.65
673
5994
395
3265
1.25
3.86
2.5
2.5
13.87
14.22
umol/l
0.44
370
3050
151
1090
1.41
3.85
14.5
11.9
1.32
1.33
%
0.03
151
1085
413
3438
1.24
3.78
3.6
2.7
0.94
1.14
e6/l
0.53
236
1703
1286
11861
1.17
3.78
8.5
7.2
0.19
0.19
e9/l
0.08
1148
10496
1082
9854
1.17
3.71
2.9
2.5
75.30
73.95
nmol/l
0.84
1009
9209
58
343
1.71
3.64
12.2
7.4
12.23
11.55
mmol/l
0.67
52
309
575
4972
1.20
3.60
2.2
1.9
1.08
1.05
mg/l
0.08
451
3717
58
344
1.70
3.60
12.2
7.4
104.77
105.39
mmol/l
0.37
52
310
145
1055
1.40
3.56
15.0
12.3
0.62
0.64
%
0.23
145
1049
751
6657
1.18
3.55
3.0
2.7
0.20
0.04
—
10
97
81
526
1.56
3.52
3.1
3.2
2.77
2.61
index
0.04
47
297
725
6415
1.18
3.49
3.8
3.2
55.85
70.91
e6/l
0.23
560
4757
637
5583
1.19
3.42
3.8
3.1
0.47
0.36
e6/l
0.51
477
3965
187
1427
1.34
3.41
2.7
3.1
68.84
71.79
e9/l
0.47
130
1002
419
3533
1.22
3.39
4.0
3.5
361.15
491.55
ng/l
0.34
299
2309
437
3701
1.22
3.39
3.2
2.8
549.77
534.97
mosm/kgh2o
0.59
385
3254
502
4315
1.20
3.34
3.0
3.1
1220.82
952.93
ng/l
0.41
422
3576
133
965
1.40
3.33
11.8
7.0
24.58
24.48
mmol/l
0.11
126
922
592
5167
1.19
3.33
3.9
3.5
1.02
1.62
kg/l
0.80
381
3375
2351
22976
1.31
3.24
18.7
15.3
72.16
71.95
umol/l
0.14
2330
22735
580
5070
1.19
3.19
1.7
1.6
19.69
20.07
nmol/l
0.28
514
4454
11
29
3.80
3.18
1.5
1.4
—
—
—
0
0
309
2542
1.25
3.16
1.9
1.6
—
—
—
0
0
361
3023
1.23
3.13
2.4
2.4
2.44
2.40
g/l
0.47
332
2812
735
6563
1.17
3.12
3.7
3.6
8.08
8.14
mmol/l
0.10
645
5763
497
4297
1.19
3.09
2.8
2.6
8.43
6.94
e6/l
0.84
452
3901
64
407
1.59
3.08
1.3
1.3
3.38
4.46
u/ml
0.49
37
185
333
2772
1.23
3.05
1.3
1.2
—
—
—
0
0
1356
12676
1.15
3.05
11.1
9.9
4.01
3.97
e9/l
0.19
1198
11044
18
74
2.44
3.04
1.3
1.8
—
—
—
0
0
230
1837
1.28
3.03
2.6
3.1
10.70
10.45
g/l
0.46
215
1712
2058
19864
1.19
2.97
4.5
4.2
5.74
5.74
mmol/l
0.05
1940
18684
335
2801
1.23
2.95
2.6
3.1
4.13
4.80
e9/l
1.66
293
2507
12
37
3.25
2.93
3.3
2.5
—
—
—
0
0
961
8788
1.15
2.92
3.8
3.3
0.01
0.03
estimate
2.30
200
1951
2005
19325
1.18
2.87
5.4
5.1
37.55
37.91
mmol/mol
1.20
1921
18500
751
6754
1.16
2.87
3.3
3.1
22.02
52.69
ng/l
1.66
418
3837
32
172
1.87
2.81
3.2
3.7
13.95
15.06
index
0.25
21
125
338
2843
1.22
2.81
2.7
2.6
30.22
29.51
s
0.88
327
2762
26
132
1.98
2.70
1.2
1.2
—
—
—
0
0
2241
21844
1.22
2.68
15.9
13.0
22.49
21.46
mg/l
0.77
1832
17571
57
367
1.57
2.65
1.1
1.2
—
—
—
0
0
324
2734
1.21
2.62
2.5
2.5
22.69
23.86
%
0.99
299
2553
50
316
1.59
2.53
2.0
1.7
—
—
—
0
0
50
316
1.59
2.53
2.0
1.7
—
—
—
0
0
50
316
1.59
2.53
2.0
1.7
—
—
—
0
0
50
316
1.59
2.53
2.0
1.7
—
—
—
0
0
22
108
2.05
2.51
1.6
1.7
2896.00
2837.65
titre
—
5
17
600
5354
1.16
2.51
3.5
3.6
48.82
51.59
mg/l
0.10
385
3474
209
1691
1.26
2.51
10.1
8.6
7.64
7.88
mmol/l
0.26
198
1635
98
713
1.39
2.49
1.3
1.2
48.10
30.28
u/ml
—
5
35
53
341
1.57
2.49
5.4
6.1
410.06
372.96
umol/l
0.83
48
304
893
8196
1.14
2.49
2.1
1.9
99.76
97.40
pmol/l
0.81
482
4495
1258
11801
1.13
2.47
3.3
3.2
95.61
93.68
ug/l
0.16
1192
11236
600
5362
1.16
2.46
2.5
2.3
2.55
2.64
mg/l
0.51
529
4703
12
45
2.67
2.45
2.0
1.2
—
0.32
—
0
9
570
5077
1.16
2.44
2.5
2.3
—
—
—
0
0
83
590
1.42
2.42
1.6
1.4
275.53
307.11
ug/g
0.58
45
316
371
3202
1.19
2.35
3.8
2.9
4.23
3.12
e6/l
0.58
196
1470
843
7740
1.13
2.30
4.6
3.7
49.61
71.96
e6/l
0.97
595
5146
84
606
1.40
2.27
3.5
2.0
3.46
1.93
ug/l
0.43
68
542
46
295
1.57
2.22
1.6
1.7
—
—
—
0
0
159
1269
1.27
2.17
2.5
2.9
67.33
67.05
g/l
0.16
151
1195
90
663
1.37
2.16
1.3
1.3
5.47
2.16
u/ml
—
6
58
45
290
1.56
2.14
2.4
2.4
—
—
—
0
0
2335
22937
1.22
2.07
12.3
10.6
26.45
26.74
u/l
0.36
2299
22438
493
4401
1.15
2.04
1.4
1.3
27.68
24.39
iu/ml
0.28
141
1270
171
1389
1.25
2.03
6.4
4.4
7.41
7.41
ph
1.03
148
1139
89
663
1.35
2.02
1.3
1.3
13.33
8.70
u/ml
—
6
99
18
90
2.01
2.00
1.8
1.3
—
—
—
0
0
72
519
1.40
1.99
2.2
2.2
9.53
10.40
g/l
1.12
66
476
2032
19753
1.14
1.99
20.7
16.1
333.52
333.38
g/l
0.29
2026
19638
271
2317
1.19
1.94
1.4
1.4
—
—
—
0
0
1677
16131
1.12
1.90
3.8
3.3
39.19
40.22
u/l
0.31
1610
15487
132
1051
1.27
1.88
7.0
4.7
—
—
—
0
0
600
5456
1.13
1.87
4.4
4.2
11.09
8.85
mg/mmol
0.35
385
3472
42
276
1.53
1.87
1.3
1.4
308.09
398.59
pmol/l
0.92
35
236
173
1422
1.23
1.87
6.5
4.4
5.16
5.12
kpa
0.36
165
1366
285
2457
1.18
1.86
3.2
3.1
7.45
6.90
umol/l
0.18
252
2131
2453
24259
1.33
1.86
24.0
19.7
6.70
6.71
e9/l
0.04
2414
23785
67
915
0.72
1.86
1.5
1.5
—
—
—
0
0
2452
24251
1.32
1.83
23.8
19.6
30.10
30.10
pg
0.09
2437
24069
178
2140
0.82
1.82
1.5
1.6
1004.60
1001.92
mu/l
0.01
148
1818
2452
24252
1.32
1.82
24.7
20.1
40.77
41.48
%
1.21
2437
24057
2451
24241
1.32
1.81
24.0
19.7
259.76
259.65
e9/l
0.03
2416
23824
100
772
1.31
1.81
2.8
3.1
—
—
—
0
0
115
905
1.28
1.80
8.0
4.9
24.50
24.49
mmol/l
0.01
107
865
2452
24254
1.32
1.80
23.9
19.6
4.57
4.57
e12/l
0.12
2413
23791
93
1203
0.76
1.79
1.5
1.5
63.54
60.02
ug/l
0.27
78
1014
184
1530
1.22
1.79
1.3
1.3
34.51
45.65
au/ml
—
10
98
2451
24250
1.31
1.73
23.9
19.6
90.08
90.07
fl
0.05
2436
24067
2452
24263
1.31
1.71
24.1
19.8
136.63
136.71
g/l
0.11
2437
24079
195
1639
1.21
1.71
2.4
2.4
14.57
20.64
au/ml
0.74
18
219
70
935
0.74
1.71
1.5
1.6
—
—
—
0
0
67
900
0.74
1.70
1.5
1.5
1.19
1.25
mm
0.71
47
646
45
308
1.47
1.68
1.2
1.5
70.81
65.30
mmol/l
0.25
36
256
43
294
1.47
1.62
1.8
1.6
34.48
95.85
mu/l
1.02
38
271
17
91
1.87
1.60
3.4
3.0
96.50
105.44
ng/l
—
10
66
707
6550
1.11
1.58
6.7
6.4
—
—
—
0
0
233
2006
1.18
1.58
2.5
2.6
29.89
63.24
u/l
0.77
194
1689
10
44
2.28
1.55
4.6
3.4
2.80
5.36
ug/l
—
10
44
42
289
1.46
1.55
1.1
1.3
—
62.62
—
0
17
23
137
1.69
1.55
3.3
3.5
786.65
862.23
u/ml
0.14
23
137
554
5079
1.12
1.50
2.6
2.5
330.94
326.70
umol/l
0.45
508
4608
415
3745
1.13
1.47
1.7
1.6
56667118.32
29377741.34
pmol/l
0.38
360
3244
91
717
1.28
1.46
3.8
4.4
282.89
408.57
mg/l
0.68
44
361
445
4037
1.12
1.45
1.3
1.3
9.00
9.12
u/ml
0.01
160
1657
21
125
1.69
1.43
3.4
4.0
0.52
0.80
index
1.41
21
125
21
125
1.69
1.43
6.2
3.3
160.56
141.47
umol/l
0.17
16
72
159
1337
1.20
1.43
1.1
1.1
—
—
—
0
0
922
9753
0.91
1.40
2.9
2.7
—
—
—
0
0
58
432
1.35
1.40
2.1
2.2
131.74
132.81
g/l
0.10
43
348
154
1295
1.20
1.39
3.0
3.1
—
—
—
0
0
649
6027
1.10
1.37
4.2
3.6
0.00
0.00
estimate
1.74
218
2195
18
104
1.74
1.37
1.3
1.3
198.50
375.72
u/l
0.89
18
93
709
6618
1.10
1.35
3.4
2.8
0.01
0.06
estimate
0.93
199
1879
932
8812
1.09
1.34
1.9
1.9
1.32
1.38
mmol/l
1.51
827
7769
21
128
1.65
1.33
1.2
1.1
—
—
—
0
0
188
1617
1.18
1.32
3.9
3.9
7.37
7.34
ph
2.35
135
1203
2028
19845
1.11
1.31
3.9
3.8
1.24
1.27
mmol/l
1.07
1927
18796
24
153
1.57
1.28
1.1
1.1
1639.13
1455.52
miu/ml
0.27
24
153
134
1591
0.83
1.27
1.5
1.7
—
—
—
0
0
134
1124
1.20
1.26
1.1
1.1
—
—
—
0
0
230
2610
0.87
1.25
1.5
1.6
3.42
3.45
mmol/l
0.17
161
1735
43
312
1.38
1.24
3.0
3.5
12.58
55.76
u/ml
0.56
43
307
114
946
1.21
1.21
5.9
3.9
1.44
1.33
%
0.35
114
940
391
3565
1.11
1.18
2.9
2.7
102.74
110.20
ug/g
0.19
319
2885
19
117
1.63
1.18
2.1
1.4
—
—
—
0
0
167
1439
1.17
1.18
1.2
1.2
63.75
119.30
titre
—
8
43
82
659
1.25
1.17
1.3
1.4
106.67
88.42
titre
—
6
76
0
34
0.00
1.16
0.0
2.0
—
—
—
0
0
15
87
1.73
1.15
2.7
4.6
—
—
—
0
0
678
6366
1.09
1.12
1.5
1.4
1.98
1.90
u/ml
0.05
189
1775
8
40
2.00
1.12
1.0
1.2
—
—
—
0
0
590
5509
1.09
1.11
5.3
4.5
—
—
—
0
0
58
740
0.78
1.10
1.0
1.1
2.67
1.17
u/ml
0.34
20
361
7
31
2.26
1.10
2.7
2.1
—
—
—
0
0
291
2622
1.12
1.10
1.3
1.2
—
—
—
0
0
5
21
2.38
1.09
1.0
1.1
—
—
—
0
0
5
21
2.38
1.09
1.0
4.2
—
—
—
0
0
8
41
1.95
1.08
1.1
1.1
—
—
—
0
0
19
120
1.59
1.08
51.2
41.2
7.39
7.38
ug/l
0.02
19
110
250
2234
1.13
1.08
1.2
1.2
—
—
—
0
0
309
3404
0.89
1.07
1.8
1.8
3.58
3.52
ratio
0.41
241
2517
58
453
1.29
1.06
1.1
1.2
—
—
—
0
0
18
113
1.60
1.05
2.1
1.4
—
—
—
0
0
44
578
0.76
1.05
1.2
1.1
11.26
19.31
au/ml
—
9
160
58
732
0.79
1.02
1.1
1.1
4.08
1.69
u/ml
0.63
27
400
120
1405
0.85
1.01
1.5
1.5
—
—
—
0
0
20
131
1.53
0.99
2.6
2.4
26.28
27.75
umol/l
0.48
20
121
221
1973
1.13
0.99
1.2
1.2
140.47
141.20
u/ml
0.01
92
732
29
206
1.41
0.98
1.1
1.3
—
196.25
—
0
8
57
450
1.27
0.98
1.7
1.7
8695.10
11489.29
e6/l
0.36
48
323
100
840
1.20
0.98
1.2
1.2
—
—
—
0
0
5
23
2.18
0.98
1.2
1.6
—
—
—
0
0
2140
21076
1.10
0.97
4.6
4.4
4.66
4.72
mmol/l
2.03
2052
20177
9
50
1.80
0.96
1.7
2.1
38.91
41.10
g/l
—
9
50
164
1439
1.15
0.95
2.8
2.3
0.43
0.35
e6/l
0.15
156
1368
13
77
1.69
0.95
1.2
1.3
—
—
—
0
0
1964
19282
1.08
0.93
19.9
15.8
13.40
13.36
%
0.91
1940
19043
164
1443
1.15
0.92
2.0
2.0
1.39
1.32
g/l
0.17
159
1353
57
455
1.26
0.91
1.7
1.8
0.91
0.76
g/l
0.20
46
362
90
755
1.20
0.91
9.5
7.6
1.30
1.28
mg/l
0.08
84
711
49
384
1.28
0.91
3.9
3.1
26.39
22.57
mg/l
0.28
34
257
18
118
1.53
0.90
2.2
1.4
63616.46
33954.12
e6/l
0.25
13
60
11
182
0.60
0.89
1.3
1.3
—
—
—
0
0
26
186
1.40
0.87
2.5
3.5
—
—
—
0
0
102
871
1.18
0.86
1.3
1.6
—
9.85
iu/ml
—
0
27
115
992
1.17
0.86
2.5
2.4
—
—
—
0
0
2129
20990
1.09
0.85
4.5
4.3
1.44
1.46
mmol/l
1.20
2037
19997
29
213
1.37
0.84
1.2
1.3
0.19
3.50
u/ml
3.06
19
115
2151
21221
1.09
0.83
5.1
4.8
2.81
2.81
mmol/l
0.04
2054
20224
55
443
1.25
0.83
2.9
3.7
28.55
41.51
mg/l
0.89
49
375
55
443
1.25
0.83
2.9
3.7
40.31
57.06
mg/l
0.58
49
375
10
57
1.76
0.83
1.1
1.0
4.01
7.34
mg/g
—
10
57
380
3529
1.09
0.83
1.6
1.6
—
—
—
0
0
24
172
1.40
0.81
1.9
1.5
—
—
—
0
0
193
1735
1.12
0.80
2.5
2.2
6.10
6.13
ph
0.13
126
1092
109
943
1.16
0.80
1.1
1.2
0.25
1.07
u/ml
—
6
68
10
58
1.73
0.79
1.1
1.0
—
—
—
0
0
17
114
1.49
0.79
2.0
1.6
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
57.90
—
0
5
9
149
0.60
0.79
1.2
1.3
65.89
75.09
umol/l
—
9
149
11
66
1.67
0.78
1.5
2.2
—
—
—
0
0
12
74
1.62
0.78
7.8
7.5
22.05
96.16
mg/mmol
1.45
12
67
64
769
0.83
0.77
1.0
1.1
5.80
6.10
u/ml
0.06
36
452
23
166
1.39
0.75
1.2
1.2
—
—
—
0
0
5
24
2.09
0.74
1.4
3.1
0.98
1.18
mg/l
—
5
18
298
2755
1.09
0.74
1.9
1.8
—
—
—
0
0
9
55
1.64
0.73
1.2
1.1
—
—
—
0
0
122
1073
1.14
0.73
1.9
1.5
9.01
8.59
u/l
0.15
98
819
44
545
0.80
0.72
1.0
1.1
0.07
0.32
u/ml
2.98
14
183
27
356
0.76
0.72
1.3
1.6
—
—
—
0
0
135
1197
1.13
0.72
2.3
1.7
0.23
0.29
mg/l
1.02
63
577
7
40
1.75
0.71
4.9
2.0
2.00
2.99
%
—
7
40
67
563
1.20
0.71
1.5
1.4
3.37
4.02
ug/l
0.59
62
519
9
57
1.58
0.71
1.6
1.5
8.20
9.69
mmol/l
—
9
57
65
545
1.20
0.70
1.4
1.5
148.96
139.21
au/ml
0.30
24
167
48
390
1.24
0.70
2.5
3.6
1.80
2.30
ratio
0.47
31
209
203
1848
1.11
0.70
1.6
1.3
196.29
254.68
u/ml
0.46
191
1730
15
101
1.49
0.70
1.1
1.2
—
—
—
0
0
19
135
1.41
0.69
2.2
1.3
4586.07
2122.87
e6/l
0.48
14
84
10
61
1.64
0.68
3.0
3.0
0.61
0.62
mmol/l
—
10
61
5
27
1.85
0.68
1.4
1.2
1.64
1.82
umol/24h
—
5
27
31
240
1.30
0.67
1.4
1.7
282.73
282.68
mosm/kgh2o
0.00
26
177
10
156
0.64
0.67
2.2
2.8
—
—
—
0
0
1037
10046
1.05
0.66
11.8
10.5
0.01
0.00
e9/l
0.51
845
8165
13
86
1.51
0.66
1.4
1.3
29.54
28.64
s
0.25
13
86
12
78
1.54
0.65
5.0
2.6
—
—
—
0
0
190
1732
1.10
0.65
3.2
2.3
6811.52
6715.19
u/l
0.01
75
665
743
7137
1.06
0.64
1.5
1.6
—
—
—
0
0
5
29
1.73
0.64
1.6
7.2
0.18
0.23
%
—
5
29
67
571
1.18
0.63
1.4
1.5
—
—
—
0
0
8
49
1.63
0.62
3.6
7.2
4.84
5.17
kpa
—
8
49
53
444
1.20
0.60
1.1
1.1
—
—
—
0
0
66
565
1.17
0.59
1.5
1.3
—
6.19
—
0
10
12
174
0.69
0.59
4.0
2.9
61.43
54.86
%
—
7
162
40
486
0.82
0.58
1.3
2.5
1.00
0.86
nmol/l
0.70
35
425
7
114
0.61
0.58
1.1
1.5
230.71
163.97
mmol/24h
—
7
114
22
167
1.32
0.56
1.6
1.3
3066.36
103188.07
e6/l
1.49
14
108
22
167
1.32
0.56
1.2
1.4
—
—
—
0
0
285
3042
0.93
0.56
1.3
1.3
—
—
—
0
0
41
338
1.22
0.56
3.7
3.9
—
—
—
0
0
6
37
1.62
0.55
1.5
1.4
—
—
—
0
0
33
266
1.24
0.55
1.5
1.3
—
—
—
0
0
73
835
0.87
0.54
1.1
1.2
4.95
2.68
u/ml
0.39
39
462
35
427
0.82
0.54
1.3
1.1
113.29
1216.10
iu/ml
—
7
115
96
853
1.13
0.54
1.3
1.3
—
—
—
0
0
11
74
1.49
0.53
3.2
2.0
15.19
16.29
umol/l
0.20
11
74
13
91
1.43
0.53
1.5
1.2
—
—
—
0
0
204
1890
1.09
0.52
1.6
1.5
25.28
23.19
iu/l
0.43
165
1557
20
152
1.32
0.52
1.5
1.2
—
65.52
—
0
12
82
725
1.14
0.51
1.7
2.0
0.24
0.23
g/l
0.38
76
683
88
986
0.89
0.49
2.0
2.1
0.00
0.01
estimate
0.88
27
349
74
838
0.88
0.49
2.0
1.7
—
—
—
0
0
199
1849
1.08
0.49
2.4
2.3
—
—
—
0
0
98
879
1.12
0.49
3.6
2.9
1.02
1.02
ratio
1.70
86
781
83
737
1.13
0.49
1.2
1.1
6.26
5.15
eliau/ml
—
9
116
20
154
1.30
0.48
1.2
1.1
—
—
—
0
0
233
2488
0.93
0.48
2.6
2.7
0.56
0.71
ug/l
2.75
119
1301
281
2649
1.07
0.47
1.7
1.5
—
—
—
0
0
49
420
1.17
0.47
2.4
1.6
426.56
349.36
mu/l
0.42
41
340
852
8285
1.04
0.45
2.0
2.0
—
—
—
0
0
84
752
1.12
0.44
1.3
1.3
—
—
—
0
0
36
302
1.19
0.44
3.2
2.9
7.01
7.32
mmol/l
0.27
36
295
67
593
1.13
0.43
2.7
3.8
213.08
844.82
u/ml
1.12
56
511
5
31
1.61
0.43
1.0
1.1
64.00
71.23
titre
—
5
31
27
328
0.82
0.43
4.9
3.9
83.04
28.06
u/ml
0.67
27
320
15
196
0.76
0.42
3.7
3.1
0.85
0.82
nmol/l
0.12
15
157
248
2342
1.07
0.41
1.4
1.5
—
—
—
0
0
5
33
1.52
0.41
1.0
6.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.20
—
0
5
33
277
1.19
0.41
1.5
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
2.2
—
3.61
—
0
8
47
540
0.87
0.40
1.3
1.3
—
—
—
0
0
54
614
0.88
0.40
1.1
1.1
2.14
4.68
u/ml
2.24
25
319
146
1354
1.08
0.40
1.3
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
58
512
1.14
0.39
4.3
2.4
7.22
6.19
umol/l
0.19
40
389
38
443
0.86
0.39
1.2
1.1
—
—
—
0
0
7
106
0.66
0.39
2.6
3.0
42.43
44.59
%
—
7
106
7
106
0.66
0.39
5.1
6.0
9.14
7.85
%
—
7
106
83
751
1.11
0.38
1.7
2.0
1.19
1.18
g/l
0.05
77
709
50
438
1.14
0.38
1.1
1.1
—
—
—
0
0
11
80
1.38
0.38
1.3
1.3
298.60
96.66
nmol/l
—
5
59
15
192
0.78
0.38
4.0
3.1
—
—
—
0
0
33
280
1.18
0.37
1.5
1.4
0.44
0.37
g/l
0.53
25
205
33
280
1.18
0.37
1.5
1.4
2.50
2.86
g/l
0.65
25
208
38
327
1.16
0.37
1.4
1.4
—
—
—
0
0
33
281
1.18
0.36
1.5
1.4
6.91
6.57
g/l
0.20
24
209
197
1857
1.07
0.36
2.2
2.1
—
—
—
0
0
23
189
1.22
0.36
1.5
1.6
46.42
54.98
%
0.43
12
125
53
597
0.89
0.36
1.6
1.5
0.29
0.41
nmol/l
1.18
41
470
26
217
1.20
0.35
2.0
3.0
—
—
—
0
0
31
363
0.85
0.35
4.7
3.8
2.06
2.33
mmol/l
0.24
16
222
195
1841
1.06
0.35
2.3
2.2
—
—
—
0
0
201
1900
1.06
0.34
1.9
2.0
0.00
0.02
estimate
1.30
43
443
10
73
1.37
0.34
1.4
3.1
85.47
78.01
ug/l
—
10
73
36
311
1.16
0.34
1.1
1.1
—
—
—
0
0
164
1541
1.07
0.34
3.4
4.4
107.18
17.02
ug/l
0.42
130
1199
12
91
1.32
0.33
5.0
2.5
—
—
—
0
0
197
1864
1.06
0.33
2.5
2.3
—
—
—
0
0
132
1234
1.07
0.32
2.4
2.2
7.22
7.81
ug/l
0.14
116
1112
15
187
0.80
0.32
1.1
1.0
—
—
—
0
0
16
128
1.25
0.32
1.7
2.7
0.14
0.22
e9/l
—
10
66
24
202
1.19
0.31
2.8
2.1
1.08
0.90
%
0.42
17
129
7
96
0.73
0.31
1.0
1.1
—
—
—
0
0
35
305
1.15
0.30
1.5
1.3
—
0.39
nmol/l
—
0
16
7
53
1.32
0.30
2.9
1.8
—
—
—
0
0
7
53
1.32
0.30
1.4
1.4
—
—
—
0
0
26
221
1.18
0.30
1.4
1.4
45.05
39.71
nmol/l
0.27
26
195
17
138
1.23
0.30
1.8
2.3
—
—
—
0
0
18
218
0.82
0.30
1.2
1.5
—
—
—
0
0
25
212
1.18
0.30
1.2
1.1
—
—
—
0
0
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
12
93
1.29
0.30
1.0
1.0
799.14
767.14
ng/l
—
7
66
11
141
0.78
0.29
1.1
1.2
—
—
—
0
0
114
1219
0.93
0.29
1.1
1.1
0.64
0.64
ratio
—
7
124
156
1475
1.06
0.28
2.4
2.3
—
—
—
0
0
13
162
0.80
0.28
1.0
1.2
8.00
8.04
mm/h
0.01
13
162
27
233
1.16
0.27
1.1
1.2
0.34
2.92
u/ml
1.54
14
96
16
131
1.22
0.27
1.4
1.5
33.11
33.93
%
—
10
83
22
187
1.18
0.26
13.2
14.2
0.66
0.61
mmol/l
0.58
22
170
93
867
1.08
0.26
2.3
2.2
—
—
—
0
0
128
1208
1.06
0.26
1.3
1.3
188.43
227.37
miu/ml
0.75
63
600
569
5556
1.03
0.25
1.6
1.5
2.20
2.20
g/l
0.00
364
3567
42
467
0.90
0.25
1.2
1.2
—
—
—
0
0
9
74
1.22
0.25
2.0
2.1
—
186.40
—
0
12
9
75
1.20
0.25
1.0
1.1
—
—
—
0
0
70
649
1.08
0.23
1.3
1.2
—
—
—
0
0
193
1850
1.05
0.23
5.4
4.9
0.90
0.93
%
0.04
47
531
12
97
1.24
0.23
1.8
1.7
—
—
—
0
0
38
342
1.11
0.23
1.4
1.4
—
10.40
—
0
5
11
88
1.25
0.22
2.0
1.9
84.97
107.57
ng/l
0.77
11
88
180
1725
1.05
0.22
2.4
2.3
—
—
—
0
0
52
477
1.09
0.22
1.7
1.9
—
—
—
0
0
133
1398
0.95
0.22
4.1
3.6
1.23
1.23
mmol/l
0.20
118
1200
184
1766
1.05
0.21
5.3
4.7
0.68
0.63
%
0.13
45
506
0
11
0.00
0.21
0.0
1.0
—
12.33
—
0
5
0
10
0.00
0.21
0.0
1.7
—
4.35
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
16
188
0.85
0.21
1.1
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.10
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
80
750
1.07
0.21
1.2
1.3
—
—
—
0
0
18
209
0.86
0.21
1.2
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
9.5
—
68.00
—
0
6
11
89
1.24
0.21
1.0
1.2
1.66
4.28
u/ml
0.41
11
78
53
573
0.92
0.20
1.1
1.1
4.96
6.15
u/ml
0.18
26
273
6
50
1.20
0.19
2.2
2.0
—
—
—
0
0
19
216
0.88
0.17
1.0
1.1
1.58
4.74
u/ml
—
9
59
187
1808
1.04
0.17
5.9
5.2
0.05
0.32
%
0.77
41
418
116
1212
0.96
0.17
1.3
1.3
—
—
—
0
0
7
63
1.11
0.17
1.1
1.8
—
—
—
0
0
23
205
1.12
0.17
1.1
1.1
—
—
—
0
0
5
67
0.75
0.17
2.8
2.3
2.40
2.53
ug/l
—
5
58
5
67
0.75
0.17
2.2
2.3
3.56
3.70
ug/l
—
5
62
17
194
0.88
0.16
2.5
2.6
1.80
1.48
g/24h
—
9
127
169
1748
0.96
0.16
4.2
3.6
—
—
—
0
0
6
79
0.76
0.15
4.8
2.1
28.50
30.66
%
—
6
79
18
203
0.89
0.15
2.7
3.9
—
—
—
0
0
21
188
1.12
0.14
1.1
1.1
—
—
—
0
0
183
1776
1.03
0.14
5.6
5.0
0.16
0.12
%
0.20
37
454
35
377
0.93
0.13
2.2
2.5
20.72
112.59
ug/min
3.62
19
238
9
110
0.82
0.13
1.1
1.1
—
—
—
0
0
17
190
0.89
0.13
1.4
1.1
110.82
115.49
pmol/l
0.26
17
190
41
384
1.07
0.12
4.6
3.6
—
—
—
0
0
420
4133
1.02
0.12
3.8
4.2
1.88
1.94
ug/l
0.05
388
3787
209
2139
0.98
0.12
4.0
4.1
31.78
31.52
%
0.14
158
1559
24
221
1.09
0.11
6.4
4.6
765.68
66.82
u/ml
0.82
12
68
410
4159
0.98
0.11
1.9
1.9
—
—
—
0
0
142
1383
1.03
0.10
2.1
1.6
342.66
288.67
mu/l
1.16
127
1255
63
657
0.96
0.10
1.3
1.4
197.09
235.66
u/ml
1.01
43
387
124
1207
1.03
0.09
2.0
1.9
—
—
—
0
0
157
1535
1.02
0.09
1.2
1.2
—
—
—
0
0
11
124
0.89
0.09
3.9
3.7
1.11
1.42
ug/l
0.36
11
118
6
54
1.11
0.09
1.3
1.1
—
—
—
0
0
6
54
1.11
0.09
1.3
1.1
—
—
—
0
0
6
54
1.11
0.09
1.3
1.1
—
—
—
0
0
10
88
1.14
0.08
1.8
1.7
—
—
—
0
0
10
88
1.14
0.08
1.2
1.6
81.80
95.84
nmol/24h
—
10
88
18
166
1.08
0.07
1.1
1.1
—
—
—
0
0
8
76
1.05
0.07
1.0
1.3
16.52
17.16
umol/l
—
8
64
22
235
0.94
0.07
1.1
1.2
1.41
14.98
u/ml
—
8
79
10
89
1.12
0.07
1.0
1.0
—
—
—
0
0
8
93
0.86
0.06
1.0
2.4
7.39
8.13
mmol/l
—
8
93
18
193
0.93
0.06
1.2
1.1
—
—
—
0
0
13
119
1.09
0.06
2.0
2.4
749.00
611.45
ml
—
7
84
13
119
1.09
0.06
1.1
1.4
135.14
135.31
nmol/l
0.01
13
119
56
543
1.03
0.06
1.1
1.1
—
—
—
0
0
10
90
1.11
0.05
1.1
1.1
—
—
—
0
0
15
139
1.08
0.05
1.1
1.0
—
—
—
0
0
27
258
1.05
0.04
1.4
1.3
—
—
nmol/l
—
0
0
62
635
0.98
0.04
1.1
1.1
—
—
—
0
0
42
433
0.97
0.04
1.1
1.0
5.25
3.41
eliau/ml
0.28
18
221
11
119
0.92
0.04
1.1
1.2
640.00
987.50
titre
—
5
24
38
369
1.03
0.03
3.8
3.6
3.74
3.96
e9/l
0.41
38
369
77
757
1.02
0.03
1.1
1.2
—
—
—
0
0
26
270
0.96
0.03
2.4
2.2
—
—
—
0
0
16
169
0.95
0.03
2.4
2.1
0.68
3.14
u/ml
—
5
60
19
181
1.05
0.03
1.2
1.4
167.96
218.43
pmol/l
0.43
19
181
660
6618
1.00
0.02
2.1
2.1
—
—
—
0
0
10
93
1.08
0.02
1.1
1.2
—
—
—
0
0
160
1589
1.01
0.02
1.4
1.4
—
—
—
0
0
51
518
0.98
0.01
3.5
3.2
58.83
57.01
%
0.53
51
518
18
187
0.96
0.01
1.1
1.1
—
—
—
0
0
27
277
0.97
0.01
1.9
2.0
—
—
—
0
0
47
463
1.02
0.01
2.4
2.4
—
—
—
0
0
62
613
1.01
0.01
8.7
9.0
—
—
—
0
0
13
125
1.04
0.00
2.5
2.2
2.00
1.80
u/field
—
6
75
16
165
0.97
0.00
1.6
1.6
0.44
0.49
e9/l
0.46
16
165
63
635
0.99
0.00
1.1
1.1
—
—
—
0
0
10
96
1.04
0.00
2.8
3.4
—
—
—
0
0
11
108
1.02
0.00
1.1
1.1
122.55
229.14
iu/ml
1.98
11
108
19
192
0.99
0.00
1.7
2.9
0.63
0.69
e9/l
0.27
19
187
93
932
1.00
0.00
1.6
1.6
15.74
11.53
u/ml
0.30
22
254
532
5318
1.00
0.00
1.7
1.7
—
—
—
0
0
197
1973
1.00
0.00
2.5
2.3
12.94
12.83
nmol/l
0.07
185
1817
24
237
1.01
0.00
1.4
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
2.31
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
31.21
—
0
8
18
180
1.00
-0.00
1.3
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
31.15
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
0.92
—
0
9
8
82
0.98
-0.00
1.0
2.8
17.71
17.24
%
—
8
82
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
71.71
—
0
8
0
9
0.00
-0.00
0.0
7.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.2
—
435.33
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
1500.83
—
0
6
5
57
0.88
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
345.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_CONVERSTRAB and mortality.

Females

Parameter HR [95% CI] p-value
H7_CONVERSTRAB 1.266 [1.03, 1.56] 0.027
Birth year 0.993 [0.98, 1.0] 0.115

During the follow-up period (1.1.1998 — 31.12.2019), 231 out of 8389 females with H7_CONVERSTRAB died.

Males

Parameter HR [95% CI] p-value
H7_CONVERSTRAB 1.261 [1.02, 1.56] 0.03
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 237 out of 7962 males with H7_CONVERSTRAB died.

Mortality risk

Mortality risk for people of age

years, who have H7_CONVERSTRAB.

N-year risk Females Males
1 0.12% 0.25%
5 0.741% 1.622%
10 1.733% 3.733%
15 3.213% 7.03%
20 5.683% 11.43%

Relationships between endpoints

Index endpoint: H7_CONVERSTRAB – Convergent concomitant strabismus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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