central nervous system disease: A disease involving the central nervous system.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
527 |
4. Check minimum number of eventsNone |
527 |
5. Include endpointsNone |
527 |
6. Filter based on genotype QC (FinnGen only) |
476 |
Control definitions (FinnGen only)
- Control exclude
- G6_OTHNEU
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G90-G99
- Name in latin
- Aliae morbositates systematis nervosi centralis
Similar endpoints
↥List of similar endpoints to
Other disorders of central nervous system
based on the number of shared cases.
Similar with more cases:
- Other neurological diseases
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3599 | 1799 | 1755 |
| Only index persons | 2683 | 1459 | 1224 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.05 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 51.05 | 50.08 | 51.69 |
| Only index persons | 46.73 | 46.94 | 46.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 476 | 296 | 180 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.08 |
| Median age at first event (years) | 50.02 | 46.53 | 55.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 491
- Matched controls
- 4910
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
+∞
265.5
230
*
G96.9
ICD-10 Finland
Disorder of central nervous system, unspecified
+∞
132.4
121
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
9.2
97.1
141
207
3499X
ICD-9 Finland
Other and unspecified disorders of the nervous system, Unspecified disorders of nervous system
+∞
81.6
76
*
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
50.7
78.8
46
10
AA1AD
NOMESCO Finland
CT of head and brain
5.2
71.2
232
724
TAB00
NOMESCO Finland
Lumbar puncture
9.0
60.0
81
106
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.9
52.8
112
236
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
11.0
50.8
57
58
G96.8
ICD-10 Finland
Other specified disorders of central nervous system
+∞
49.8
47
*
M03BX01
ATC
baclofen; systemic
13.0
42.4
42
35
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
9.9
35.3
42
46
R51.80
ICD-10 Finland
Headache
3.6
35.1
150
531
N03AX14
ATC
levetiracetam; systemic
9.7
34.7
42
47
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
188.0
34.2
35
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
6.0
33.8
64
119
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
11.0
33.7
37
36
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.0
33.6
80
183
G96.1
ICD-10 Finland
Disorders of meninges, not elsewhere classified
+∞
29.5
28
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.6
25.3
51
100
N03AF02
ATC
oxcarbazepine; oral
6.6
25.0
42
69
WX882
NOMESCO Finland
High dependency care
7.5
24.9
37
53
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
262.8
24.9
25
*
XCK00
NOMESCO Finland
Perimetry
4.9
24.8
58
130
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
23.8
86
267
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
6.1
23.3
42
74
N03AX12
ATC
[U] gabapentin; oral
3.1
22.9
118
457
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.4
22.2
94
323
H02AB09
ATC
hydrocortisone; systemic
6.9
22.0
35
54
N03AX16
ATC
[U] pregabalin
2.8
21.8
149
671
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.1
21.8
48
102
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
24.6
20.2
28
12
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
19.9
19
*
X59
ICD-10 Finland
Exposure to unspecified factor
2.7
19.9
136
609
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
19.8
106
416
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
18.8
102
403
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
7.3
18.0
27
39
ZXD05
NOMESCO Finland
Urgent procedure
2.4
17.7
186
1009
R1250
NOMESCO Finland
Evaluation of functional capability
5.8
17.7
33
60
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.7
17.5
25
34
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
17.3
133
626
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
52.0
17.1
20
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
16.3
78
286
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
16.3
131
628
S18
ICPC
Laceration/cut
2.2
16.1
259
1659
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.5
15.9
60
190
WX402
NOMESCO Finland
General anaesthesia
2.4
15.9
136
669
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
+∞
15.7
15
*
ZXC95
NOMESCO Finland
Use of surgical navigator
12.9
15.5
27
22
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
11.8
15.5
28
25
CS494
NOMESCO Finland
Other visual field testing
7.0
15.4
24
36
L89
ICD-10 Finland
Decubitus ulcer and pressure area
7.3
15.4
23
33
N03AE01
ATC
clonazepam; systemic
4.0
15.3
46
125
R20.2
ICD-10 Finland
Paraesthesia of skin
3.4
15.2
58
185
G35
ICD-10 Finland
Multiple sclerosis
12.4
14.7
26
22
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
+∞
14.7
14
*
L28
ICPC
Limited function/disability (L)
2.5
14.4
106
485
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.0
14.2
31
65
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.0
14.2
31
65
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
14.2
244
1578
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
14.1
151
813
G03.9
ICD-10 Finland
Meningitis, unspecified
31.1
14.0
18
6
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
13.7
67
248
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
13.6
68
255
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
13.5
93
411
AAK10
NOMESCO Finland
Repair of dura
143.8
13.5
14
*
109
Kela drug reimbursment
Multiple sclerosis
18.9
13.5
20
11
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
18.9
13.5
20
11
H53.2
ICD-10 Finland
Diplopia
5.0
13.2
29
61
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.9
13.2
30
65
A28
ICPC
Limited function/disability NOS
2.5
13.0
95
431
G82.2
ICD-10 Finland
Paraplegia, unspecified
29.3
13.0
17
6
AA1BD
NOMESCO Finland
Extensive CT of head and brain
5.8
13.0
24
43
R4120
NOMESCO Finland
Occupational therapy
3.3
12.9
51
166
XKC03
NOMESCO Finland
Water cystometry
5.3
12.8
26
51
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
16.0
12.7
20
13
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.8
12.7
40
112
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.9
12.7
64
241
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
12.6
12
*
Z3226
NOMESCO Finland
Physiotherapist
2.3
12.5
111
549
N02AX02
ATC
tramadol; systemic, rectal
2.0
12.3
225
1465
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
38.6
12.3
15
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.5
12.2
43
130
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.5
12.2
43
130
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
12.2
80
345
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
18.6
12.1
18
10
M54.4
ICD-10 Finland
Lumbago with sciatica
2.3
12.0
110
551
N18
ICPC
Paralysis/weakness
9.3
11.9
24
27
R4110
NOMESCO Finland
Physiotherapy
2.1
11.9
154
885
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
10.9
11.9
22
21
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
13.0
11.7
20
16
R42
ICD-10 Finland
Dizziness and giddiness
2.2
11.7
121
637
TKC20
NOMESCO Finland
Catheterisation of bladder
3.4
11.7
44
139
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
+∞
11.5
11
*
ZZC00
NOMESCO Finland
Graft of fascia
122.8
11.5
12
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
11.4
51
179
XKD06
NOMESCO Finland
Physiologic investigation of micturition
4.9
11.3
25
53
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.9
11.3
25
53
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
11.3
108
550
H02AB06
ATC
prednisolone; systemic
1.9
11.3
246
1686
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
11.5
11.1
20
18
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
11.0
186
1170
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
10.9
123
668
R41.0
ICD-10 Finland
Disorientation, unspecified
5.3
10.9
22
43
R55
ICD-10 Finland
Syncope and collapse
2.7
10.8
63
255
UDM02
NOMESCO Finland
Sinoscopy
5.1
10.8
23
47
R50.9
ICD-10 Finland
Fever, unspecified
2.3
10.8
95
466
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.6
10.7
67
281
Z2446
NOMESCO Finland
Social worker
3.0
10.6
49
175
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
112.3
10.5
11
*
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
16.5
10.4
16
10
WX892
NOMESCO Finland
Monitored bed care
3.0
10.2
48
173
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.7
10.1
21
25
Z2445
NOMESCO Finland
Psychologist
3.5
10.1
36
110
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.6
10.0
62
259
R53
ICD-10 Finland
Malaise and fatigue
2.0
10.0
140
821
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
9.8
36
112
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.7
9.8
55
219
A02BC02
ATC
pantoprazole; systemic
1.9
9.6
333
2590
N99
ICPC
Neurological disease other
11.7
9.6
17
15
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.8
9.6
51
197
Z3231
NOMESCO Finland
Registered nurse
1.9
9.6
146
879
B01AB05
ATC
enoxaparin; parenteral
1.9
9.5
157
970
WX002
NOMESCO Finland
Sedation and analgesia
2.1
9.5
98
512
ZXA10
NOMESCO Finland
Bilateral
2.1
9.5
98
512
E23.00
ICD-10 Finland
Panhypopituitarism
30.7
9.4
12
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
+∞
9.4
9
*
L04AA31
ATC
[U] teriflunomide
+∞
9.4
9
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
9.4
9
*
G93.2
ICD-10 Finland
Benign intracranial hypertension
+∞
9.4
9
*
DC1AD
NOMESCO Finland
Temporalbone CT
11.0
9.4
17
16
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
14.0
9.2
15
11
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.4
9.2
23
54
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.4
9.2
23
54
ZX120
NOMESCO Finland
Intravenous
2.6
9.2
57
238
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.1
9.2
25
63
N02AA05
ATC
oxycodone; systemic
2.2
9.2
91
468
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
9.1
135
803
N06AA09
ATC
amitriptyline; systemic
2.6
9.1
54
221
S02.10
ICD-10 Finland
Fracture of base of skull, closed
19.0
9.0
13
7
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
11.0
8.8
16
15
R01AD08
ATC
fluticasone; nasal
1.9
8.8
153
957
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.1
8.7
24
61
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
8.7
76
371
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
7.1
8.6
20
29
N03AG01
ATC
valproic acid; systemic, rectal
3.0
8.6
39
138
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
10.3
8.6
16
16
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
6.6
8.6
21
33
G44.2
ICD-10 Finland
Tension-type headache
2.1
8.5
85
437
R4130
NOMESCO Finland
Speech therapy
4.0
8.5
24
62
N06AX21
ATC
duloxetine; oral
2.3
8.4
70
335
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
8.4
71
342
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
8.4
8
*
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
+∞
8.4
8
*
R13
ICD-10 Finland
Dysphagia
2.8
8.3
43
164
UJF32
NOMESCO Finland
Coloscopy
1.9
8.3
122
722
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.3
8.3
32
103
R35
ICD-10 Finland
Polyuria
2.8
8.2
41
153
ZXA05
NOMESCO Finland
Left side
1.9
8.1
116
679
J01DB01
ATC
cefalexin; oral
2.0
8.1
405
3438
ZXC86
NOMESCO Finland
Use of endoscopic device
22.5
8.0
11
5
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
8.0
41
155
N02BE01
ATC
paracetamol; systemic, rectal
2.3
8.0
436
3808
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
8.0
103
582
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
7.9
57
255
X58
ICD-10 Finland
Exposure to other specified factors
2.1
7.9
86
456
101
Kela drug reimbursment
Anterior pituitary hypofunction
13.3
7.9
13
10
N02BF02
ATC
pregabalin; oral
2.7
7.9
45
180
M54.5
ICD-10 Finland
Low back pain
1.8
7.9
185
1260
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
7.9
80
414
ZZF00
NOMESCO Finland
Graft of adipose tissue
8.7
7.9
16
19
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
11.0
7.8
14
13
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.8
7.7
23
62
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
7.7
81
425
J01EA01
ATC
trimethoprim; systemic
1.8
7.7
129
795
WX725
NOMESCO Finland
Noninvasive ventilation
3.0
7.6
34
119
L03AX13
ATC
glatiramer acetate; parenteral
18.7
7.6
11
6
H47.2
ICD-10 Finland
Optic atrophy
18.7
7.6
11
6
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
25.5
7.6
10
*
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
9.1
7.6
15
17
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.2
7.6
30
98
SPAT1167
SPAT
Insertion of urinary catheter
4.5
7.5
18
41
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
7.5
80
422
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
7.4
214
1536
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.1
7.4
75
387
P01AB01
ATC
metronidazole; oral, rectal
1.7
7.4
200
1410
N06AB04
ATC
citalopram; systemic
1.9
7.4
107
627
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
7.4
186
1287
R52.2
ICD-10 Finland
Other chronic pain
3.3
7.4
28
89
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.4
7.3
26
79
AWW99
NOMESCO Finland
Other reoperation in surgery of the nervous system
+∞
7.3
7
*
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
+∞
7.3
7
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.4
7.3
18
42
L03AB07
ATC
interferon beta-1a; parenteral
16.0
7.3
11
7
SPAT1229
SPAT
Assessment of need for aid
2.8
7.2
37
140
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.1
7.2
29
96
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
6.2
7.1
18
30
L03
ICPC
Low back symptom/complaint
1.8
7.1
150
985
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.1
7.1
69
350
R33
ICD-10 Finland
Retention of urine
2.6
7.1
42
172
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.8
7.0
34
125
J01DA01
ATC
[U] cefalexin
1.7
7.0
297
2345
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
7.0
356
2952
H57.1
ICD-10 Finland
Ocular pain
3.0
7.0
30
103
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.0
6.9
79
426
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.5
6.9
24
72
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.8
6.9
34
126
C03CA01
ATC
furosemide; systemic
1.8
6.9
124
777
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
6.8
70
364
PA2AD
NOMESCO Finland
CT angiography of brain
17.0
6.8
10
6
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.8
6.7
33
122
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
6.7
134
864
G43.9
ICD-10 Finland
Migraine, unspecified
2.5
6.7
42
176
R25.1
ICD-10 Finland
Tremor, unspecified
3.8
6.7
20
54
R51
ICD-10 Finland
Headache
2.7
6.7
36
140
ZXE00
NOMESCO Finland
One hour or less
1.7
6.7
189
1341
N03AX11
ATC
topiramate; oral
3.7
6.7
21
59
N01
ICPC
Headache
2.0
6.7
73
388
N04BB01
ATC
amantadine; oral
8.0
6.7
14
18
WX872
NOMESCO Finland
Intensive care
3.1
6.6
28
95
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.6
6.6
22
64
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.4
6.6
23
69
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.6
6.6
39
159
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
3.9
6.6
19
50
A04
ICPC
Weakness/tiredness general
2.0
6.6
80
441
N28
ICPC
Limited function/disability (N)
7.0
6.6
15
22
XKD00
NOMESCO Finland
Uroflowmetry
2.1
6.5
65
333
U13
ICPC
Bladder symptom/complaint other
3.7
6.5
20
55
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.0
6.5
28
96
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
6.5
179
1258
R11
ICD-10 Finland
Nausea and vomiting
2.2
6.5
53
251
G00.1
ICD-10 Finland
Pneumococcal meningitis
70.7
6.4
7
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
6.4
41
174
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.2
6.4
17
42
ZXD35
NOMESCO Finland
Usual procedure
3.7
6.4
20
56
PA6AD
NOMESCO Finland
CT of neck arteries
3.7
6.4
20
56
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
6.3
54
260
U07
ICPC
Urine symptom/complaint other
2.3
6.3
48
220
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
6.3
41
175
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
6.3
26
87
R52.0
ICD-10 Finland
Acute pain
3.1
6.3
26
87
H47.1
ICD-10 Finland
Papilloedema, unspecified
11.2
6.3
11
10
R06.2
ICD-10 Finland
Wheezing
3.0
6.3
28
98
Q01.1
ICD-10 Finland
Nasofrontal encephalocele
+∞
6.3
6
*
G45.3
ICD-10 Finland
Amaurosis fugax
+∞
6.3
6
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
+∞
6.3
6
*
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
+∞
6.3
6
*
AAK00
NOMESCO Finland
Cranioplasty
+∞
6.3
6
*
ABD40
NOMESCO Finland
Implantation of spinal injection device
+∞
6.3
6
*
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
+∞
6.3
6
*
G93.0
ICD-10 Finland
Cerebral cysts
+∞
6.3
6
*
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
+∞
6.3
6
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
+∞
6.3
6
*
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
27.0
6.2
8
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
6.4
6.2
15
24
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.9
6.2
16
28
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
6.2
149
1011
R60.9
ICD-10 Finland
Oedema, unspecified
2.8
6.1
30
111
U72
ICPC
Urethritis
4.2
6.1
16
39
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
8.8
6.1
12
14
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
8.8
6.1
12
14
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
6.1
75
416
Z71.8
ICD-10 Finland
Other specified counselling
1.6
6.0
179
1278
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
6.0
148
1007
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
6.0
45
205
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
6.0
151
1033
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
97
90
13.18
93.40
1.6
1.3
3.55
3.68
mmol/l
0.38
92
82
64
29
25.23
88.51
1.7
1.2
—
—
—
0
0
89
84
12.72
84.48
1.7
1.3
343.00
13.75
e6/l
1.42
71
64
89
86
12.42
83.15
1.8
1.4
4990.67
219.37
e6/l
0.89
72
67
152
553
3.53
33.94
2.1
2.2
28.55
29.39
s
1.44
146
534
35
32
11.70
33.23
1.2
1.1
44.33
28.38
mg/l
0.85
30
23
32
30
11.34
29.84
1.1
1.0
—
—
—
0
0
120
421
3.45
27.83
7.7
9.1
14.31
12.24
kpa
3.17
115
405
120
421
3.45
27.83
7.7
9.1
5.19
5.21
kpa
0.08
115
403
36
13
29.75
27.08
1.6
1.3
—
—
—
0
0
294
1732
2.74
25.93
10.6
12.1
1.15
1.19
inr
0.79
249
1429
116
416
3.34
25.82
7.8
9.2
0.45
1.07
mmol/l
0.76
99
343
320
2003
2.72
24.40
9.7
7.3
1.21
1.22
mmol/l
1.07
295
1744
32
43
7.89
22.74
1.1
1.0
—
—
—
0
0
292
1798
2.54
22.22
10.2
6.8
1.21
1.22
mmol/l
2.14
280
1673
191
974
2.57
21.67
2.8
2.4
—
—
—
0
0
348
2352
2.65
21.35
7.8
5.0
6.45
6.58
mmol/l
0.59
334
2217
124
513
2.90
21.20
6.9
7.7
105.53
104.40
mmol/l
1.83
124
513
96
356
3.11
19.85
8.0
10.0
121.03
122.42
g/l
0.27
91
348
209
1183
2.33
18.13
2.9
2.1
134.69
266.30
u/l
1.37
203
1125
69
225
3.40
17.54
7.6
10.3
23.89
24.40
mmol/l
0.65
69
220
187
1021
2.34
17.52
5.7
4.0
93.95
92.91
%
0.24
182
1004
273
1766
2.23
16.75
4.9
4.9
35.63
36.34
g/l
1.20
262
1673
135
651
2.48
16.58
2.3
1.9
—
—
—
0
0
286
1905
2.20
16.06
3.7
2.8
—
—
estimate
—
0
0
112
513
2.53
15.23
6.0
6.4
1.00
1.07
mmol/l
1.75
103
471
78
302
2.88
14.73
2.5
2.4
29.95
16.57
au/ml
—
6
27
132
661
2.36
14.71
2.9
4.0
0.83
0.82
mmol/l
0.37
127
634
87
364
2.69
14.16
7.0
8.4
1.09
1.26
mmol/l
1.62
87
358
335
2453
2.15
13.79
13.1
10.0
4.35
4.05
e9/l
1.25
301
2130
100
455
2.50
13.68
2.3
1.8
—
—
—
0
0
194
1168
2.09
13.51
5.3
3.1
0.15
0.32
e6/l
2.20
157
827
159
892
2.16
13.28
3.4
2.8
4.29
6.49
e6/l
1.39
149
813
101
474
2.42
12.87
2.3
1.8
—
—
—
0
0
353
2673
2.14
12.81
7.3
4.3
146.80
787.68
e6/l
—
5
40
303
2171
2.03
12.77
6.9
6.6
10.09
11.20
umol/l
0.83
288
2081
25
27
9.69
12.62
1.1
1.0
1.16
1.05
u/l
0.47
11
13
60
222
2.94
12.24
9.5
8.4
25.35
24.74
mmol/l
0.66
55
211
211
1347
1.99
12.20
5.2
3.3
21.51
90.98
e6/l
0.78
172
1008
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
22
20
11.46
12.15
1.2
1.2
—
—
—
0
0
24
27
9.29
11.88
1.4
1.2
0.64
0.48
ratio
1.16
16
13
72
304
2.60
11.41
3.8
2.5
67.72
67.66
g/l
0.03
66
285
58
224
2.80
10.92
2.1
1.8
—
—
—
0
0
19
17
11.57
10.63
1.2
1.1
—
—
—
0
0
219
1467
1.89
10.57
4.3
3.6
20.65
80.34
ng/l
0.82
148
971
19
19
10.35
10.09
1.2
1.1
—
—
—
0
0
21
27
8.07
9.71
2.5
1.5
—
—
—
0
0
88
441
2.21
9.46
3.9
4.6
235.56
253.58
u/l
0.68
77
422
12
6
20.45
8.50
1.7
1.0
—
—
—
0
0
78
394
2.16
8.17
5.3
4.9
1.79
1.69
mmol/l
0.08
68
336
154
988
1.81
8.07
2.1
1.8
1.23
1.32
mg/l
0.11
120
768
373
3096
1.85
7.77
5.7
4.3
12.96
10.97
mm/h
1.75
356
2903
73
373
2.12
7.41
3.8
3.2
—
—
—
0
0
103
597
1.92
7.36
1.8
1.6
1155.56
1196.25
nmol/l
0.16
86
455
17
26
6.73
7.17
3.4
2.6
—
—
—
0
0
10
5
20.37
7.16
1.4
1.0
—
—
—
0
0
120
740
1.82
7.04
5.0
2.7
1.47
0.95
e6/l
0.60
65
376
372
3137
1.77
6.72
10.7
8.0
78.85
79.16
u/l
0.05
362
2984
456
4132
2.45
6.43
27.1
14.3
20.28
22.96
mg/l
1.57
417
3324
157
1071
1.68
6.39
3.2
2.3
2.91
2.85
mg/l
0.11
132
937
17
31
5.64
6.35
3.4
1.9
600.25
491.57
e6/l
0.38
12
23
111
688
1.79
6.35
5.3
2.8
2.75
2.88
e6/l
0.06
55
322
94
558
1.85
6.18
3.5
2.5
19.97
22.76
%
1.39
89
526
29
106
2.84
6.06
2.0
1.4
—
—
—
0
0
17
33
5.30
6.06
3.5
2.0
207.50
200.22
e6/l
0.05
12
27
55
272
2.15
6.05
2.1
1.6
—
—
—
0
0
455
4139
2.35
6.01
29.8
16.5
3.95
3.96
mmol/l
0.23
455
4057
25
87
2.97
5.70
1.8
1.4
—
—
—
0
0
13
20
6.64
5.59
2.7
4.1
566.69
632.55
u/ml
0.09
13
20
32
130
2.56
5.49
1.7
2.0
10.17
10.52
g/l
0.20
27
120
23
78
3.04
5.49
1.2
1.2
—
—
—
0
0
23
78
3.04
5.49
1.2
1.2
—
—
—
0
0
102
643
1.74
5.45
3.4
2.5
11.79
13.27
umol/l
1.21
94
601
20
63
3.27
5.37
1.2
1.1
—
—
—
0
0
11
14
8.01
5.37
1.2
1.1
—
—
—
0
0
19
58
3.37
5.36
1.4
1.4
0.55
0.56
nmol/l
0.07
19
53
175
1272
1.58
5.35
2.9
2.6
51.68
64.65
u/l
1.81
160
1192
51
258
2.09
5.31
8.1
5.3
2.01
1.84
mmol/l
0.14
39
194
274
2210
1.54
5.23
5.0
3.7
0.05
4.10
estimate
0.49
66
459
272
2199
1.53
5.07
5.0
3.7
0.00
0.00
estimate
-0.00
66
455
226
1757
1.53
5.05
2.4
2.0
97.39
96.44
pmol/l
0.10
122
908
275
2230
1.53
5.04
5.0
3.8
0.05
0.02
estimate
0.27
65
426
153
1095
1.58
4.93
2.8
3.4
1060.27
1203.19
ng/l
0.15
129
924
30
125
2.49
4.90
2.4
2.8
—
—
—
0
0
157
1135
1.56
4.83
1.8
1.6
18.82
20.84
nmol/l
0.99
137
978
28
115
2.52
4.72
1.3
1.3
—
—
—
0
0
10
14
7.27
4.67
1.2
1.0
—
—
—
0
0
10
14
7.27
4.67
1.2
1.2
—
—
—
0
0
33
148
2.32
4.61
2.4
1.9
0.79
3.06
ug/l
0.66
23
136
192
1468
1.51
4.50
3.5
3.3
31.17
30.65
u/l
0.05
182
1397
39
193
2.11
4.32
1.1
1.2
0.18
3.07
u/ml
—
6
9
373
3283
1.57
4.31
5.8
4.4
14.78
14.63
pmol/l
0.51
348
3051
10
16
6.35
4.31
1.2
1.3
—
—
—
0
0
9
13
7.03
4.18
1.1
1.2
—
—
—
0
0
39
196
2.08
4.15
1.6
1.4
—
—
—
0
0
20
74
2.78
4.13
2.7
3.7
5.32
4.98
kpa
1.19
20
74
108
741
1.59
4.09
3.9
3.4
46.71
368.73
ng/l
3.21
76
532
334
2892
1.48
3.99
4.2
3.4
55.11
42.28
u/l
1.31
322
2766
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
23
94
2.52
3.94
3.3
3.7
0.34
0.37
iu/ml
0.17
11
54
23
94
2.52
3.94
1.3
1.4
—
—
—
0
0
11
23
4.87
3.89
1.0
1.0
711.83
625.77
ng/l
—
6
13
181
1403
1.46
3.83
3.0
3.3
2.35
2.36
mmol/l
0.39
163
1280
7
8
8.85
3.78
1.1
1.4
—
—
—
0
0
24
103
2.40
3.73
1.3
1.5
—
—
—
0
0
231
1883
1.43
3.69
3.0
2.5
75.27
75.71
nmol/l
0.09
208
1724
12
30
4.07
3.61
1.2
1.1
—
—
—
0
0
28
131
2.21
3.59
4.0
3.0
158.79
185.41
%
1.05
28
126
29
138
2.17
3.57
1.4
1.3
—
—
—
0
0
30
145
2.14
3.55
2.1
2.0
—
—
—
0
0
19
75
2.60
3.50
3.1
4.5
—
989.50
—
0
6
12
33
3.70
3.31
3.5
2.9
14.14
12.74
index
—
7
23
11
28
3.99
3.30
1.8
2.6
—
—
—
0
0
419
3858
1.59
3.27
6.8
5.3
1.68
1.86
mu/l
3.19
399
3599
28
137
2.11
3.23
2.0
1.8
—
—
—
0
0
14
50
2.85
3.11
1.4
1.3
—
—
—
0
0
6
8
7.57
3.06
1.2
1.0
—
—
—
0
0
6
8
7.57
3.06
1.2
1.0
—
—
—
0
0
145
1118
1.42
3.04
1.5
1.3
0.79
1.51
u/ml
0.82
35
299
16
63
2.59
2.98
1.0
1.2
—
—
—
0
0
28
142
2.03
2.96
2.8
2.9
104.64
93.65
%
1.44
28
137
152
1187
1.41
2.96
5.1
3.9
0.00
0.01
estimate
0.96
64
430
54
340
1.66
2.89
1.4
1.2
449.10
186.62
u/ml
0.45
48
313
7
13
5.45
2.88
1.1
1.1
—
—
—
0
0
8
18
4.50
2.80
1.5
1.6
8.63
13.78
u/l
—
8
18
22
104
2.17
2.79
3.5
2.6
3.00
1.70
index
0.63
12
63
71
489
1.53
2.63
2.7
3.1
8.23
6.46
umol/l
0.33
61
429
243
2076
1.34
2.61
4.4
3.1
104.51
102.06
ug/l
0.08
224
1961
35
203
1.78
2.52
1.6
2.2
5.72
7.14
iu/ml
0.18
12
45
17
76
2.28
2.47
1.2
1.4
—
—
—
0
0
5
8
6.30
2.37
1.2
1.3
—
—
—
0
0
7
17
4.16
2.36
1.7
1.5
111.86
74.12
nmol/24h
—
7
17
45
286
1.63
2.35
2.5
2.4
5.79
6.87
ug/l
0.26
39
259
417
3902
1.46
2.32
23.2
13.7
86.84
84.54
ml/min/173m2
1.41
395
3591
457
4361
1.69
2.32
31.2
18.0
73.54
74.26
umol/l
0.18
457
4315
8
23
3.52
2.28
1.3
1.0
—
—
—
0
0
104
796
1.39
2.23
2.9
2.8
2.45
2.45
mmol/l
0.24
90
712
166
1367
1.32
2.22
3.7
3.3
7.99
7.98
mmol/l
0.00
141
1169
50
332
1.56
2.19
1.2
1.3
91.26
164.06
u/ml
0.86
16
145
13
56
2.36
2.06
1.3
1.6
—
—
—
0
0
57
396
1.50
2.05
2.9
2.4
26.89
31.86
u/l
1.12
47
331
129
1035
1.33
2.04
3.2
2.7
340.77
336.66
umol/l
0.17
105
926
36
227
1.63
1.97
2.9
3.9
0.65
0.60
%
0.54
36
227
100
778
1.36
1.94
1.7
1.7
453.59
23680676.22
pmol/l
0.69
87
663
19
99
1.96
1.93
2.9
2.3
139.00
128.61
g/l
1.49
12
75
119
956
1.32
1.86
1.9
1.7
—
—
—
0
0
151
1254
1.29
1.85
4.0
4.1
7.44
9.31
mg/mmol
0.21
89
767
45
305
1.52
1.83
2.9
3.6
1.23
1.23
mmol/l
0.43
38
264
15
73
2.09
1.82
1.3
1.5
—
—
—
0
0
12
53
2.30
1.82
1.6
1.4
—
—
—
0
0
9
35
2.60
1.81
1.0
1.2
122.00
114.57
pmol/l
—
9
35
64
469
1.42
1.77
5.0
4.2
32.24
31.32
%
0.26
46
312
17
88
1.97
1.77
1.4
1.4
0.22
0.33
nmol/l
—
10
67
6
18
3.36
1.75
1.0
2.6
83.83
108.94
ug/l
—
6
18
20
112
1.82
1.67
1.8
1.4
—
—
—
0
0
13
62
2.13
1.67
1.5
1.5
2.21
3.34
ug/l
—
8
54
106
851
1.31
1.66
1.5
1.4
19.73
31.10
iu/ml
0.57
27
268
7
25
2.83
1.65
1.1
2.0
—
—
—
0
0
7
25
2.83
1.65
1.1
2.0
—
—
—
0
0
99
788
1.32
1.65
1.4
1.3
2.45
13.69
u/ml
3.89
36
304
35
230
1.56
1.65
2.9
3.9
1.15
1.25
%
0.24
35
230
46
322
1.47
1.63
1.5
1.4
—
—
—
0
0
309
2837
1.24
1.51
4.0
3.3
—
—
—
0
0
412
3916
1.32
1.49
4.8
4.7
5.88
5.84
mmol/l
0.15
390
3647
17
94
1.84
1.49
1.2
1.8
—
—
—
0
0
10
45
2.25
1.47
5.4
1.4
18.14
23.70
ug/l
—
10
45
19
110
1.76
1.45
1.4
1.4
281.55
317.58
ug/g
0.43
11
66
5
16
3.15
1.44
3.8
6.8
—
—
—
0
0
20
118
1.72
1.43
1.6
1.5
—
—
—
0
0
401
3805
1.29
1.41
6.7
5.9
39.22
38.67
mmol/mol
0.52
381
3611
145
1236
1.25
1.40
4.3
3.1
0.04
0.01
estimate
0.34
57
361
450
4347
1.42
1.36
16.9
11.4
26.18
26.03
u/l
0.07
442
4247
16
90
1.80
1.34
1.6
1.4
—
—
—
0
0
10
47
2.15
1.34
1.9
1.8
—
—
—
0
0
11
55
2.02
1.28
1.1
1.2
—
—
—
0
0
8
35
2.31
1.27
2.0
1.6
—
—
—
0
0
6
25
2.42
1.24
1.5
1.2
—
—
—
0
0
57
438
1.34
1.23
10.2
6.1
—
—
—
0
0
10
49
2.06
1.22
1.8
1.3
—
—
—
0
0
19
117
1.65
1.20
1.1
1.2
—
—
—
0
0
28
190
1.50
1.19
4.9
2.1
947.35
3748.84
u/l
0.89
11
70
19
118
1.63
1.16
1.1
1.2
—
—
—
0
0
5
20
2.51
1.15
1.2
1.6
—
—
—
0
0
5
20
2.51
1.15
1.6
1.3
—
—
—
0
0
5
20
2.51
1.15
1.6
1.3
—
—
—
0
0
10
51
1.98
1.12
2.8
2.7
103.60
105.78
mmol/l
—
10
51
5
21
2.39
1.09
1.2
1.1
0.31
0.26
g/l
—
5
15
8
41
1.97
1.09
1.9
1.9
—
—
—
0
0
7
32
2.20
1.08
1.0
1.0
274.14
285.07
mg/l
—
7
27
28
393
0.70
1.07
1.5
1.8
3.60
3.52
mmol/l
0.14
20
289
21
138
1.55
1.04
1.2
1.3
—
—
—
0
0
12
68
1.78
1.01
1.2
1.3
1.50
1.48
u/ml
—
6
27
12
68
1.78
1.01
1.2
1.2
3.00
3.30
u/ml
—
6
30
18
115
1.59
1.01
1.1
1.1
—
3.34
—
0
14
9
48
1.89
1.01
1.0
1.2
89.67
98.77
%
—
9
43
7
133
0.52
1.00
1.6
1.5
—
—
—
0
0
462
4512
1.41
0.99
39.7
22.0
90.97
90.78
fl
0.40
462
4484
17
108
1.59
0.98
1.2
1.5
335.40
253.28
u/ml
—
10
61
9
50
1.81
0.97
3.0
2.7
1.21
1.20
mmol/l
—
9
50
462
4515
1.39
0.95
40.6
22.5
39.67
40.47
%
2.92
462
4484
462
4518
1.38
0.92
40.1
22.1
132.34
135.37
g/l
4.83
462
4488
31
228
1.38
0.91
1.1
1.3
—
—
—
0
0
23
161
1.45
0.88
1.8
1.3
—
—
—
0
0
6
30
2.01
0.87
1.5
1.5
—
—
—
0
0
185
1680
1.16
0.86
4.9
3.6
0.06
0.04
estimate
0.16
62
374
8
45
1.79
0.84
2.8
4.3
—
—
—
0
0
41
517
0.77
0.82
1.7
2.0
3.84
3.47
ratio
1.04
30
414
9
56
1.62
0.72
1.3
1.4
—
—
—
0
0
9
57
1.59
0.71
1.3
1.4
—
—
—
0
0
9
57
1.59
0.71
1.3
1.4
—
—
—
0
0
9
144
0.62
0.70
1.6
1.6
70.86
55.12
ug/l
—
9
122
16
110
1.47
0.69
1.3
1.2
—
—
—
0
0
5
27
1.86
0.68
1.4
1.4
—
—
—
0
0
15
102
1.49
0.68
10.9
3.2
1.24
2.11
ratio
—
8
57
11
70
1.58
0.65
1.5
1.6
—
—
—
0
0
21
155
1.37
0.64
1.3
1.2
—
1.33
—
0
6
5
29
1.73
0.64
1.2
1.3
—
—
—
0
0
43
352
1.24
0.64
2.0
2.1
—
—
—
0
0
18
130
1.40
0.62
1.2
1.2
—
—
—
0
0
22
165
1.35
0.61
1.4
1.6
—
—
—
0
0
8
54
1.49
0.57
1.4
1.4
—
—
—
0
0
8
54
1.49
0.57
1.4
1.4
—
—
—
0
0
6
36
1.67
0.57
2.0
1.1
—
—
—
0
0
6
36
1.67
0.57
2.0
1.1
—
—
—
0
0
11
73
1.52
0.56
1.9
4.4
45.00
8.23
pmol/l
0.53
11
73
8
55
1.46
0.56
1.4
1.4
—
—
—
0
0
17
125
1.37
0.54
2.4
1.8
35.35
42.05
nmol/l
0.83
17
119
39
323
1.23
0.54
2.8
2.6
75.33
67.09
ml/min/173m2
0.77
21
140
11
75
1.48
0.51
1.4
1.5
—
—
—
0
0
15
201
0.74
0.50
1.3
1.1
1.59
1.56
g/l
0.29
15
201
11
155
0.70
0.49
1.2
1.5
—
—
—
0
0
25
199
1.27
0.49
2.8
1.5
0.21
0.29
mg/l
0.32
11
84
35
291
1.22
0.48
1.9
2.1
—
—
—
0
0
16
206
0.77
0.42
1.4
1.1
0.97
0.91
g/l
0.26
16
206
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
15
0.00
0.41
0.0
1.0
—
131.80
—
0
15
0
15
0.00
0.41
0.0
1.0
—
113.50
—
0
8
0
15
0.00
0.41
0.0
1.0
—
95.38
—
0
8
5
35
1.43
0.39
1.4
1.3
85.60
58.22
u/l
—
5
30
188
1783
1.09
0.38
1.9
1.9
1.39
1.34
mmol/l
0.28
164
1540
21
171
1.24
0.36
2.1
1.5
—
—
—
0
0
6
43
1.40
0.35
1.0
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
61
550
1.12
0.34
2.4
1.8
1.55
1.43
%
0.60
53
499
6
45
1.34
0.34
1.0
1.2
—
—
—
0
0
6
45
1.34
0.34
1.0
1.2
—
—
—
0
0
6
47
1.28
0.32
1.2
1.0
—
—
—
0
0
83
765
1.10
0.32
1.5
1.5
—
—
—
0
0
35
400
0.87
0.32
3.0
4.4
8.81
35.49
ug/l
0.70
27
328
110
1029
1.09
0.31
4.9
5.3
2.17
2.43
ug/l
0.30
98
933
7
52
1.35
0.31
1.1
1.4
—
—
—
0
0
7
96
0.73
0.31
1.7
1.7
—
—
—
0
0
7
54
1.30
0.30
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
7.88
—
0
6
355
3607
0.94
0.21
34.2
18.4
332.11
332.51
g/l
0.36
355
3590
5
43
1.16
0.21
2.0
1.5
—
—
—
0
0
5
43
1.16
0.21
2.0
1.5
—
—
—
0
0
5
43
1.16
0.21
2.0
1.5
—
—
—
0
0
6
48
1.25
0.20
1.0
1.1
—
—
—
0
0
14
165
0.84
0.19
1.4
1.8
—
—
—
0
0
7
62
1.13
0.17
1.3
1.3
—
—
—
0
0
7
63
1.11
0.17
1.6
1.4
—
—
—
0
0
17
189
0.90
0.12
1.3
1.3
142.12
252.11
miu/ml
—
8
98
24
261
0.92
0.12
1.1
1.0
—
—
—
0
0
15
167
0.89
0.11
1.6
1.5
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
61
633
0.96
0.09
3.5
3.0
0.79
0.79
ug/l
0.00
42
410
54
562
0.96
0.08
2.4
2.1
—
—
—
0
0
6
56
1.07
0.08
1.3
1.1
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
1.39
1.45
g/l
—
5
54
81
834
0.97
0.08
4.5
4.5
21.90
21.72
%
0.04
42
397
7
65
1.08
0.08
1.1
1.3
—
—
—
0
0
6
72
0.83
0.07
1.7
1.5
52.81
52.78
ug/l
—
6
72
14
128
1.10
0.06
1.4
1.9
2.60
5.20
iu/l
—
6
48
413
4117
1.02
0.03
5.6
5.4
2.68
2.77
mmol/l
0.83
390
3866
407
4060
1.01
0.02
5.1
4.9
4.61
4.71
mmol/l
1.28
383
3827
61
619
0.98
0.02
2.3
2.2
—
—
—
0
0
405
4057
0.99
0.01
5.0
4.8
1.41
1.49
mmol/l
3.51
379
3802
386
3867
0.99
0.01
4.2
4.1
1.36
1.26
mmol/l
1.37
359
3598
99
992
1.00
0.00
4.6
3.7
1.02
1.02
kg/l
0.04
63
652
5
55
0.91
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
1.1
1.1
—
1.12
—
0
30
0
5
0.00
-0.00
0.0
1.0
—
52.40
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
7.17
—
0
7
11
110
1.00
-0.00
1.3
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
85
0.94
-0.00
1.8
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
6.10
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
1.24
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
1.72
—
0
7
0
6
0.00
-0.00
0.0
7.0
—
10.35
—
0
6
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.8
—
0.50
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint G6_CNSOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_CNSOTH | 2.546 [1.94, 3.33] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.811 |
During the follow-up period (1.1.1998 — 31.12.2019), 160 out of 1017 females with G6_CNSOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_CNSOTH | 2.416 [1.86, 3.13] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.03 |
During the follow-up period (1.1.1998 — 31.12.2019), 195 out of 815 males with G6_CNSOTH died.
Mortality risk
Mortality risk for people of age
years, who have G6_CNSOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.256% | 0.513% |
| 5 | 1.547% | 2.716% |
| 10 | 3.976% | 7.605% |
| 15 | 7.418% | 14.388% |
| 20 | 12.607% | 23.066% |
Relationships between endpoints
↥Index endpoint: G6_CNSOTH – Other disorders of central nervous system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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