Other and unspecified disorders of white blood cells

D3_WHITEBLOODCELLNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D72.8, D72.9
  • Hospital discharge: ICD-9 288[8-9]
  • Cause of death: ICD-10 D72.8, D72.9
  • Cause of death: ICD-9 288[8-9]

2 out of 7 registries used, show all original rules.

1953

4. Check minimum number of events

None

1953

5. Include endpoints

None

1953

6. Filter based on genotype QC (FinnGen only)

1520

Control definitions (FinnGen only)

Control exclude
D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11640 6110 5442
Only index persons 9637 5134 4503
Unadjusted period prevalence (%)
Whole population 0.16 0.18 0.15
Only index persons 0.18 0.19 0.17
Median age at first event (years)
Whole population 59.46 58.68 60.22
Only index persons 57.31 56.07 58.71

-FinnGen-

Key figures

All Female Male
Number of individuals 1520 820 700
Unadjusted period prevalence (%) 0.30 0.29 0.32
Median age at first event (years) 57.80 53.29 63.08

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1603
Matched controls
16030
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
60.5
307.7
255
50
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
9256.0
307.7
1249
6
XW000
NOMESCO Finland
Bone marrow biopsy
29.6
307.7
521
257
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
15.4
307.7
352
288
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
451.6
307.7
328
9
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
61.6
297.3
166
30
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
28.4
185.0
126
48
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.5
144.7
454
1304
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
43.0
103.2
62
15
L01XX05
ATC
hydroxycarbamide; oral
16.5
100.7
86
55
D70.89
ICD-10 Finland
Neutropenic splenomegaly
170.0
92.2
96
6
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
32.8
88.2
57
18
2888B
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOPENIA]
+∞
82.0
78
*
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
125.0
77.7
83
7
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
9.4
74.6
91
102
L03AA02
ATC
filgrastim; parenteral
6.9
73.9
118
182
M04AA01
ATC
allopurinol; systemic
3.2
73.2
347
1264
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
66.6
955
5988
R50.9
ICD-10 Finland
Fever, unspecified
2.8
61.3
370
1530
WW500
NOMESCO Finland
Blood transfusion
5.1
58.8
131
277
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
23.3
56.5
41
18
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
13.1
53.0
51
40
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
50.6
270
1037
189
Kela drug reimbursment
Imatinib
78.4
47.2
53
7
L01XE01
ATC
[U] imatinib
96.8
43.0
47
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
42.1
527
2968
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.6
42.0
146
431
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
17.0
41.9
35
21
JN4BD
NOMESCO Finland
Extensive body CT
2.8
40.9
229
897
C91.7
ICD-10 Finland
Other lymphoid leukaemia
210.2
40.0
41
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
7.9
39.7
55
72
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
107.8
38.9
42
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
38.7
37
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
38.3
217
854
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
73.4
38.1
43
6
127
Kela drug reimbursment
Transplant complication
6.8
35.4
56
85
J01MA12
ATC
levofloxacin; systemic
2.2
35.3
365
1887
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.5
34.7
127
387
L01EA01
ATC
imatinib; oral
66.5
34.1
39
6
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
66.5
34.1
39
6
JN6AD
NOMESCO Finland
CT of torso and neck
6.0
32.7
58
99
ZX120
NOMESCO Finland
Intravenous
2.6
31.9
197
807
A04AA01
ATC
ondansetron; systemic, rectal
2.7
31.6
181
714
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
30.9
231
1036
H02AB06
ATC
prednisolone; systemic
1.8
30.7
817
5794
H02AB09
ATC
hydrocortisone; systemic
4.7
30.3
72
160
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.6
30.0
199
843
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
84.3
29.8
33
*
JN4AD
NOMESCO Finland
Body CT examination
2.3
28.1
241
1145
B73
ICPC
Leukaemia
65.2
28.0
32
5
316
Kela drug reimbursment
Imatinib
101.9
27.7
30
*
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
54.4
27.2
32
6
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
26.1
517
3309
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
25.8
321
1761
C03CA01
ATC
furosemide; systemic
1.8
25.3
533
3468
WW200
NOMESCO Finland
Immunization
4.1
25.3
71
180
A02BC02
ATC
pantoprazole; systemic
1.8
24.3
1121
9062
Z2221
NOMESCO Finland
Medical doctor
1.8
24.1
475
3021
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
23.8
400
2420
D45
ICD-10 Finland
Polycythaemia vera
7.5
23.8
34
46
L01XX52
ATC
venetoclax; oral
31.6
23.7
31
10
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
22.8
149
625
D72.1
ICD-10 Finland
Eosinophilia
121.8
22.6
24
*
TGC00
NOMESCO Finland
Bronchial lavation
3.9
22.5
66
173
A41.9
ICD-10 Finland
Sepsis, unspecified
3.4
22.1
82
252
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
22.0
562
3834
399
Kela drug reimbursment
Venetoclax
25.4
21.8
30
12
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.4
21.5
155
680
212
Kela drug reimbursment
Gout
4.6
21.3
51
114
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
9.1
21.2
26
29
J01MA14
ATC
moxifloxacin; systemic
2.3
21.2
173
801
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.0
21.2
95
327
J01DB01
ATC
cefalexin; oral
1.9
21.1
1327
11464
Z3231
NOMESCO Finland
Registered nurse
1.7
21.0
461
3006
A05AA02
ATC
ursodeoxycholic acid; oral
4.9
20.9
46
96
L04AD01
ATC
ciclosporin; systemic
4.7
20.6
48
105
D75.2
ICD-10 Finland
Essential thrombocytosis
111.5
20.6
22
*
1512
Kela drug reimbursment
Ibrutinib
33.0
20.2
26
8
390
Kela drug reimbursment
Ibrutinib
33.0
20.2
26
8
L01BB05
ATC
fludarabine; systemic
48.7
20.2
24
5
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
19.9
181
877
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
19.6
838
6462
152
Kela drug reimbursment
Nilotinib
202.4
19.6
20
*
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
19.6
366
2272
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
19.4
125
520
R4110
NOMESCO Finland
Physiotherapy
1.7
19.3
469
3132
L04AA06
ATC
mycophenolic acid; systemic
4.4
19.1
48
112
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
18.8
426
2790
1518, ,
Kela drug reimbursment
22.0
18.2
26
12
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
18.2
232
1273
ZXE00
NOMESCO Finland
One hour or less
1.6
18.0
625
4554
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
18.0
188
960
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
17.9
380
2439
2888A
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOCYTOSIS]
+∞
17.7
17
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
17.6
331
2052
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.5
17.4
25
34
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
24.3
17.3
24
10
ZX108
NOMESCO Finland
Inhalation
6.9
17.0
26
38
J05AB11
ATC
valaciclovir; oral
1.9
16.8
248
1426
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
6.5
16.7
27
42
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
16.6
296
1802
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.0
16.6
25
36
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
23.3
16.4
23
10
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
16.3
68
225
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
16.1
116
508
L01EL01
ATC
ibrutinib; oral
48.0
16.0
19
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
16.0
566
4113
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.9
15.9
47
124
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
4.2
15.9
42
102
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
60.6
15.8
18
*
L01XX28
ATC
[U] imatinib
161.5
15.5
16
*
B03XA02
ATC
darbepoetin alfa; parenteral
3.6
15.5
51
145
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
15.5
565
4129
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.2
15.5
62
200
L01AA02
ATC
chlorambucil; oral
17.9
15.2
23
13
Z2446
NOMESCO Finland
Social worker
2.2
15.0
125
583
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
12.6
14.9
26
21
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
14.8
311
1978
Z3226
NOMESCO Finland
Physiotherapist
1.7
14.8
298
1875
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
14.6
190
1045
328
Kela drug reimbursment
Nilotinib
151.3
14.5
15
*
J01MA02
ATC
ciprofloxacin; systemic
1.5
14.5
605
4542
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.2
14.4
120
559
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
14.4
177
955
N05AA02
ATC
levomepromazine; systemic
2.7
14.3
76
288
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
12.1
14.1
25
21
A46
ICD-10 Finland
Erysipelas
1.8
14.0
248
1504
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.0
14.0
60
202
R03BB04
ATC
tiotropium bromide; inhalant
1.9
13.9
180
989
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
3.4
13.9
49
146
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
13.7
119
564
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
13.7
256
1574
B03XA01
ATC
erythropoietin; parenteral
5.5
13.6
26
48
150
Kela drug reimbursment
Dasatinib
141.2
13.5
14
*
L01EA03
ATC
nilotinib; oral
141.2
13.5
14
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.8
13.3
67
247
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
13.1
218
1295
N05CF01
ATC
zopiclone; oral
1.5
13.1
492
3590
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
2.7
13.1
70
266
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
12.9
575
4348
SPAT1255
SPAT
Intravenous administration of medicine
2.2
12.9
115
552
ZX112
NOMESCO Finland
Subcutaneous
3.4
12.8
46
139
WX402
NOMESCO Finland
General anaesthesia
1.6
12.7
352
2394
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.2
12.7
113
542
J02AC03
ATC
voriconazole; systemic
15.6
12.6
20
13
A07AA02
ATC
nystatin; oral
2.3
12.6
100
457
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
12.6
156
844
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
32.3
12.6
16
5
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.9
12.5
59
210
N03AE01
ATC
clonazepam; systemic
2.3
12.4
96
434
WX892
NOMESCO Finland
Monitored bed care
2.0
12.4
133
684
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
12.4
68
262
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
12.3
140
735
D75.1
ICD-10 Finland
Secondary polycythaemia
37.8
12.2
15
*
J01FF01
ATC
clindamycin; systemic
1.5
12.2
414
2950
UJF32
NOMESCO Finland
Coloscopy
1.5
11.9
403
2868
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
11.8
188
1101
L01AA01
ATC
cyclophosphamide; systemic
11.8
11.8
21
18
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.3
11.8
91
411
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
4.3
11.8
30
71
L04AD02
ATC
tacrolimus; systemic
4.8
11.7
26
55
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
16.5
11.7
18
11
N05BA01
ATC
diazepam; systemic, rectal
1.8
11.7
204
1229
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
65.4
11.6
13
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
11.6
380
2682
N06AB04
ATC
citalopram; systemic
1.6
11.5
306
2058
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
13.7
11.5
19
14
L01XE06
ATC
[U] dasatinib
120.9
11.4
12
*
N06AX16
ATC
venlafaxine; oral
1.7
11.4
218
1346
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.4
435
3170
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.4
652
5147
T90
ICPC
Diabetes non-insulin dependent
1.5
11.2
385
2744
120
Kela drug reimbursment
Hypogammaglobulinaemia
25.2
11.1
15
6
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
11.1
74
314
9101
FHL
Bone biopsy
43.6
10.9
13
*
N07BA03
ATC
varenicline; oral
2.4
10.8
77
336
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.8
10.8
52
187
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
10.8
183
1093
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
10.7
252
1643
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
10.6
712
5767
XF600
NOMESCO Finland
Bloodpressure measurement
2.1
10.5
106
533
J01CA04
ATC
amoxicillin; systemic
1.5
10.5
1248
11205
A02BC01
ATC
omeprazole; systemic
1.5
10.5
405
2951
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.4
10.4
72
310
L01XE08
ATC
[U] nilotinib
110.7
10.4
11
*
1XC02, ,
NOMESCO Finland
5.5
10.4
20
37
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
16.2
10.4
16
10
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
12.1
10.3
18
15
B99
ICPC
Blood/lymph/spleen disease other
12.1
10.3
18
15
L01XE27
ATC
[U] ibrutinib
32.7
10.3
13
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
10.2
291
1983
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.2
10.2
84
390
ZY010
NOMESCO Finland
Hospital outpatient
2.2
10.2
84
391
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
10.1
213
1349
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
11.4
10.1
18
16
C83.1
ICD-10 Finland
Mantle cell lymphoma
11.4
10.1
18
16
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
5.1
10.1
21
42
E0000UV, ,
ATC
1.4
10.0
614
4876
H02AB07
ATC
prednisone; oral
1.7
10.0
203
1273
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
10.0
351
2505
N03AX16
ATC
[U] pregabalin
1.5
10.0
341
2419
J05AB01
ATC
aciclovir; systemic
1.5
9.9
322
2260
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
16.8
9.9
15
9
L04AA01
ATC
[U] ciclosporin
4.3
9.9
25
59
R4190
NOMESCO Finland
Nutritional therapy
2.3
9.8
72
319
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.6
9.8
32
91
N02BE01
ATC
paracetamol; systemic, rectal
1.6
9.8
1386
12790
L04AX01
ATC
azathioprine; systemic
2.4
9.7
66
282
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.7
275
1871
R05
ICPC
Cough
1.5
9.7
381
2782
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
55.3
9.7
11
*
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
55.3
9.7
11
*
A03
ICPC
Fever
1.6
9.6
250
1667
N05AH02
ATC
clozapine; systemic
3.3
9.6
35
107
J01AA02
ATC
doxycycline; systemic
1.5
9.6
1175
10489
R02
ICPC
Shortness of breath/dyspnoea
1.6
9.6
214
1375
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
9.6
88
428
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
9.5
159
944
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
4.0
9.5
26
65
Z51.5
ICD-10 Finland
Palliative care
1.8
9.4
139
795
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
100.6
9.4
10
*
B84
ICPC
Unexplained abnormal white cells
100.6
9.4
10
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
17.6
9.4
14
8
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
9.4
220
1430
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
9.4
165
994
D07AB08
ATC
desonide; topical
1.7
9.4
163
979
R4120
NOMESCO Finland
Occupational therapy
2.0
9.3
105
551
R53
ICD-10 Finland
Malaise and fatigue
1.5
9.2
380
2797
R60.0
ICD-10 Finland
Localized oedema
1.7
9.2
197
1253
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
3.9
9.2
26
67
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.0
9.1
95
484
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
9.1
118
648
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
9.1
132
752
UJF92
NOMESCO Finland
Capsular endoscopy
3.0
9.1
39
132
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.8
9.1
20
42
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.4
9.1
60
254
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
9.0
198
1265
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
9.0
285
1984
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
9.0
370
2718
C95.9
ICD-10 Finland
Leukaemia, unspecified
36.9
9.0
11
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
9.0
62
267
ZXD05
NOMESCO Finland
Urgent procedure
1.4
9.0
447
3404
L04AX03
ATC
methotrexate; systemic
1.8
8.9
146
861
R03AC02
ATC
salbutamol; inhalant
1.4
8.9
810
6828
P01AB01
ATC
metronidazole; oral, rectal
1.4
8.9
577
4603
A06AD11
ATC
lactulose; oral
1.6
8.9
222
1465
D07AC01
ATC
betamethasone; topical
1.4
8.8
529
4162
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
8.8
298
2104
SPAT1263
SPAT
Sampling
1.4
8.8
601
4835
SPAT1262
SPAT
Handing over of treatment supplies
1.5
8.8
258
1768
L03AA13
ATC
pegfilgrastim; parenteral
2.3
8.8
68
309
RS220, ,
NOMESCO Finland
3.6
8.7
28
79
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.0
8.7
38
130
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.9
8.6
107
580
L28
ICPC
Limited function/disability (L)
1.5
8.6
290
2046
N02AA05
ATC
oxycodone; systemic
1.5
8.6
282
1979
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
3.6
8.6
27
75
N05AF03
ATC
chlorprothixene; systemic
2.8
8.5
42
154
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
27.7
8.5
11
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
3.7
8.5
26
71
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
8.5
171
1070
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
8.4
130
754
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.0
8.4
37
127
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
3.3
8.4
31
96
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
7.9
8.4
18
23
J12.8
ICD-10 Finland
Other viral pneumonia
4.7
8.4
19
41
9831/3-C42.1
ICD-O-3
T-cell large granular lymphocytic leukemia of bone marrow
+∞
8.3
8
*
TAB00
NOMESCO Finland
Lumbar puncture
2.1
8.3
73
349
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
10.8
8.3
15
14
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.2
8.3
72
343
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.1
8.3
76
370
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
8.3
641
5250
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.2
8.2
31
97
AA1AD
NOMESCO Finland
CT of head and brain
1.4
8.2
436
3352
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
8.2
368
2747
A02BC05
ATC
esomeprazole; systemic
1.4
8.1
581
4692
N06AX11
ATC
mirtazapine; oral
1.4
8.1
493
3878
N03AX09
ATC
lamotrigine; oral
2.1
8.1
72
346
374
Kela drug reimbursment
Ruxolitinib
33.5
8.1
10
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
17.3
8.1
12
7
R55
ICD-10 Finland
Syncope and collapse
1.6
8.1
171
1083
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
8.0
604
4917
Z2445
NOMESCO Finland
Psychologist
2.3
8.0
60
269
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.7
8.0
40
148
R51.80
ICD-10 Finland
Headache
1.5
8.0
228
1552
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
3.3
7.9
29
89
J01FA09
ATC
clarithromycin; systemic
1.4
7.9
433
3343
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.0
7.9
81
411
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.1
7.9
32
105
P01BA02
ATC
hydroxychloroquine; oral
1.8
7.9
118
679
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
3.6
7.9
25
70
K59.1
ICD-10 Finland
Functional diarrhoea
1.9
7.9
91
482
R05
ICD-10 Finland
Cough
1.5
7.8
314
2290
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.0
7.8
34
116
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.2
7.8
65
304
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.8
542
4352
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
7.8
197
1303
J01FA10
ATC
azithromycin; systemic
1.3
7.8
807
6889
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.5
7.8
270
1914
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.6
7.7
42
162
ZXA05
NOMESCO Finland
Left side
1.4
7.7
352
2630
B01AB05
ATC
enoxaparin; parenteral
1.4
7.7
458
3583
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.3
7.7
54
235
C07AB07
ATC
bisoprolol; oral
1.3
7.6
729
6141
N03AX12
ATC
[U] gabapentin; oral
1.5
7.6
237
1642
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
18.4
7.6
11
6
TPH00
NOMESCO Finland
Phlebotomy
8.1
7.6
16
20
R04.2
ICD-10 Finland
Haemoptysis
2.3
7.6
56
250
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
7.5
137
833
N05BA04
ATC
oxazepam; oral
1.4
7.5
382
2910
N05AH04
ATC
quetiapine; oral
1.5
7.5
251
1766
N05AH03
ATC
olanzapine; systemic
1.9
7.5
94
512
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.7
7.5
143
882
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
2.9
7.5
33
114
324
Kela drug reimbursment
Dasatinib
80.5
7.4
8
*
N05AB03
ATC
perphenazine; systemic, rectal
2.3
7.4
54
240
A28
ICPC
Limited function/disability NOS
1.5
7.4
270
1934
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
4.0
7.4
20
50
TQW99
NOMESCO Finland
Other minor procedure on skin
2.0
7.4
81
422
J02AC01
ATC
fluconazole; systemic
1.4
7.3
521
4189
6BA02, ,
NOMESCO Finland
10.9
7.3
13
12
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
7.3
7
*
2888X
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOCYTOPATHIA ALIA DEFINITA]
+∞
7.3
7
*
D72
ICD-10 Finland
Other disorders of white blood cells
+∞
7.3
7
*
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
7.3
7
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
7.3
7
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
7.3
232
1615
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
7.3
415
3221
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.9
7.2
33
116
C03DA01
ATC
spironolactone; oral
1.6
7.2
185
1227
Z31.5
ICD-10 Finland
Genetic counselling
2.0
7.2
76
390
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.2
7.2
61
288
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
7.2
106
607
SPAT1254
SPAT
Administration of medicine
1.5
7.2
210
1434
R06AE07
ATC
cetirizine; oral
1.3
7.2
606
4997
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.0
7.2
73
370
R31
ICD-10 Finland
Unspecified haematuria
1.6
7.2
157
1003
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
7.2
1062
9505
L01EJ01
ATC
ruxolitinib; oral
30.1
7.1
9
*
174
Kela drug reimbursment
Ruxolitinib
30.1
7.1
9
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
7.1
117
692
B02.9
ICD-10 Finland
Zoster without complication
1.8
7.1
105
602
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.0
7.1
77
399
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
7.1
199
1347
RD210, ,
NOMESCO Finland
2.9
7.1
32
112
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
8.8
7.0
14
16
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
7.0
394
3045
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
7.0
89
486
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
7.0
138
857
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
4.2
7.0
18
43
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.2
7.0
57
265
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.2
7.0
26
81
E000002, ,
ATC
1.6
7.0
149
946
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.9
7.0
84
452
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.2
6.9
58
273
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.6
6.9
37
142
R11
ICD-10 Finland
Nausea and vomiting
1.7
6.9
130
800
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
6.9
170
1119
R81
ICPC
Pneumonia
2.1
6.8
60
288
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.3
6.8
48
210
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.8
6.8
96
543
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.4
6.8
43
179
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
2.5
6.8
41
167
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.0
6.8
74
385
C91.4
ICD-10 Finland
Hairy-cell leukaemia
40.2
6.8
8
*
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
16.8
6.7
10
6
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.2
6.7
53
243
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
2.8
6.7
33
121
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.8
6.7
33
121
A10BA02
ATC
metformin; oral
1.4
6.7
419
3293
N05CD07
ATC
temazepam; oral
1.6
6.7
166
1092
B01AB10
ATC
tinzaparin; parenteral
1.6
6.7
161
1053
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.6
229
1619
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
6.6
112
668
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.0
6.6
70
361
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
6.6
204
1412
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
6.9
6.5
15
22
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
5.3
6.5
18
34
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.6
6.5
37
147
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
6.5
332
2526
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.2
6.5
25
80
E000001, ,
ATC
1.4
6.4
268
1964
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
70.1
6.4
7
*
D69.4
ICD-10 Finland
Other primary thrombocytopenia
70.1
6.4
7
*
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
70.1
6.4
7
*
C91
ICD-10 Finland
Lymphoid leukaemia
70.1
6.4
7
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
70.1
6.4
7
*
B74
ICPC
Malignant neoplasm blood other
14.4
6.4
10
7
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.9
6.4
79
429
R52.9
ICD-10 Finland
Pain, unspecified
1.6
6.3
150
977
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
5.2
6.3
18
35
3AC01, ,
NOMESCO Finland
3.6
6.3
20
56
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.6
6.3
158
1043
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.3
612
5128
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.2
6.3
50
231
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
18.1
6.3
9
5
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
6.3
405
3197
D73.1
ICD-10 Finland
Hypersplenism
+∞
6.3
6
*
2889X
ICD-9 Finland
Diseases of white blood cells, Unspecified disease of white blood cells
+∞
6.3
6
*
D73.0
ICD-10 Finland
Hyposplenism
+∞
6.3
6
*
C91.5
ICD-10 Finland
Adult T-cell lymphoma/leukaemia [HTLV-1-associated]
+∞
6.3
6
*
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
+∞
6.3
6
*
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
6.3
6
*
D73.5
ICD-10 Finland
Infarction of spleen
+∞
6.3
6
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
6.2
94
543
C95.1
ICD-10 Finland
Chronic leukaemia of unspecified cell type
26.8
6.2
8
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.5
6.2
37
150
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.8
6.2
84
470
XX9XE
NOMESCO Finland
Other ultrasound examination
4.0
6.2
17
43
B04
ICPC
Blood symptom/complaint
6.3
6.2
15
24
A02BC03
ATC
lansoprazole; oral
1.4
6.2
400
3158
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.1
905
8004
N03AG01
ATC
valproic acid; systemic, rectal
1.8
6.1
86
486
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
2.6
6.1
35
139
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.8
6.1
30
110
J94.8
ICD-10 Finland
Other specified pleural conditions
3.0
6.1
26
88
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.1
6.0
53
255
S01.50
ICD-10 Finland
Open wound in oral cavity
3.5
6.0
20
58
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.0
376
2950
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
3.0
6.0
26
89
PJA10
NOMESCO Finland
Exploration of lymph nodes
3.3
6.0
22
68
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.4
6.0
21
63

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
331
191
21.58
307.65
2.0
1.6
—
—
—
0
0
244
113
25.29
307.65
1.3
1.3
—
—
—
0
0
255
128
23.50
307.65
1.4
1.3
—
—
—
0
0
683
1692
6.29
279.99
5.8
2.6
1.82
1.81
%
0.07
647
1508
572
1305
6.26
253.37
6.1
2.7
73.60
69.24
e9/l
1.60
431
962
511
1123
6.21
233.80
4.0
2.9
9.48
10.81
g/l
6.56
472
1040
172
120
15.94
193.82
1.2
1.1
—
—
—
0
0
413
889
5.91
190.08
2.3
1.9
1.43
1.44
g/l
0.02
371
828
1283
6720
5.55
186.70
17.4
6.4
8.55
8.87
%
1.51
1246
6292
1280
6705
5.51
185.87
17.2
6.4
0.63
0.67
%
1.61
1244
6266
1280
6706
5.51
185.80
17.1
6.3
2.45
2.82
%
4.60
1245
6270
208
213
11.07
184.66
6.9
3.3
0.93
1.30
%
0.65
195
195
1290
6860
5.51
181.97
17.2
6.4
35.89
27.27
%
42.11
1253
6510
159
110
15.94
179.78
3.5
2.4
1782.52
1170.32
e6/l
0.47
139
99
1255
6742
4.97
168.84
15.8
6.3
50.01
57.68
%
39.61
1226
6438
139
84
18.02
168.34
2.5
2.1
67.59
72.34
%
1.19
133
79
476
1279
4.87
167.52
9.9
4.5
0.81
0.91
%
0.33
334
373
452
1228
4.73
155.84
10.1
4.3
0.50
0.67
%
1.21
322
355
1281
7298
4.76
150.99
15.1
6.2
0.06
0.04
e9/l
0.97
1162
6233
1278
7283
4.72
150.19
15.2
6.2
0.74
0.59
e9/l
7.03
1157
6221
1297
7529
4.79
147.05
17.1
6.4
0.22
0.19
e9/l
1.61
1194
6542
1286
7427
4.70
146.64
15.5
6.3
5.18
1.93
e9/l
16.80
1198
6524
433
1230
4.45
139.56
10.3
4.5
0.13
0.10
%
0.19
292
322
427
1240
4.33
133.09
10.3
4.8
0.42
0.11
%
1.01
291
293
425
1241
4.30
131.34
2.4
2.9
66.52
66.49
g/l
0.02
400
1145
373
1008
4.52
127.37
2.3
2.7
—
—
—
0
0
115
82
15.03
127.32
3.7
2.5
899.05
536.90
e6/l
0.48
88
69
1318
8162
4.46
125.95
23.0
9.3
4.44
4.16
e9/l
1.96
1223
7061
110
83
14.16
117.85
4.0
2.6
204.87
216.20
e6/l
0.17
92
75
283
680
4.84
111.14
2.4
1.8
1.27
1.53
g/l
4.71
243
598
126
134
10.12
107.87
9.0
3.5
—
—
—
0
0
155
227
7.45
102.29
1.4
1.2
53.61
43.89
u/l
0.21
143
197
168
271
6.81
101.35
1.4
1.4
—
—
—
0
0
120
138
9.32
96.76
7.3
3.2
43.00
56.40
%
4.87
103
126
1198
7592
3.29
96.03
12.0
6.4
10.91
11.60
umol/l
1.36
1164
7256
746
3700
2.90
93.47
5.4
2.8
345.62
346.51
umol/l
0.08
690
3254
154
247
6.79
93.27
1.5
1.4
152.71
154.28
au/ml
0.05
49
71
236
576
4.63
90.08
2.1
2.6
2.97
2.98
g/l
0.07
221
527
241
614
4.44
86.97
2.1
2.5
3.47
3.80
g/l
2.16
226
566
241
615
4.44
86.78
2.1
2.5
4.11
4.23
g/l
0.94
226
566
241
615
4.44
86.78
2.1
2.5
7.01
7.42
g/l
3.03
226
566
512
2139
3.05
86.75
3.5
2.7
22.79
22.50
%
0.16
483
2000
138
215
6.93
85.79
4.9
2.2
1.10
0.89
%
1.78
105
147
71
44
16.84
84.31
2.5
1.7
29.55
28.50
%
0.14
71
44
531
2321
2.93
82.23
3.4
2.6
2.32
2.31
g/l
0.25
502
2150
648
3159
2.76
81.35
11.4
4.7
—
—
—
0
0
552
2488
2.86
80.44
3.5
2.6
12.64
12.87
umol/l
0.29
522
2318
214
535
4.46
78.84
2.1
2.6
10.14
10.58
g/l
0.48
198
482
476
2023
2.92
76.91
9.6
5.9
1.05
1.03
mmol/l
0.56
456
1877
794
4371
2.62
76.87
7.9
4.2
7.40
7.40
ph
0.58
633
3152
599
2882
2.72
76.18
1.9
1.5
2.14
2.47
g/l
4.48
443
1761
1028
6431
2.67
75.90
7.6
5.1
35.30
35.54
g/l
0.65
972
6041
311
1038
3.48
75.80
1.4
1.4
—
—
—
0
0
1004
6325
2.57
71.12
25.3
11.4
0.01
0.00
e9/l
1.74
861
5158
525
2448
2.70
70.05
1.8
1.8
—
—
—
0
0
746
4137
2.50
69.03
7.1
4.4
—
—
—
0
0
1100
7323
2.60
67.88
12.8
7.4
1.21
1.21
mmol/l
0.21
940
6353
194
503
4.25
67.81
2.6
4.0
45.78
60.22
mg/l
0.55
165
433
194
504
4.24
67.63
2.6
4.0
37.58
76.13
mg/l
0.94
164
436
181
453
4.38
66.23
2.5
3.8
3.13
4.07
ratio
0.19
113
264
53
30
18.24
65.61
2.6
2.4
3.44
0.25
e9/l
0.80
34
15
1012
6573
2.46
64.34
11.9
6.7
1.21
1.21
mmol/l
0.55
965
6082
516
2477
2.60
63.98
6.4
3.5
0.81
0.82
mmol/l
1.45
498
2343
381
1572
2.87
63.65
1.6
1.6
—
—
—
0
0
136
279
5.23
63.31
1.3
1.3
246.57
262.42
u/ml
0.22
91
162
175
445
4.29
62.62
1.3
1.3
—
—
—
0
0
451
2067
2.64
61.09
1.6
1.6
—
—
—
0
0
140
313
4.81
58.86
5.2
3.3
49.91
58.64
%
5.56
140
313
57
47
12.54
57.55
1.1
1.1
—
—
—
0
0
73
86
8.85
57.49
2.6
2.7
34.73
42.26
%
1.10
30
42
163
427
4.14
55.91
2.9
2.7
3.58
3.63
g/l
0.13
158
406
93
151
6.48
55.29
2.3
2.5
13.49
52.36
iu/ml
1.59
17
20
399
1798
2.62
55.28
4.5
3.2
5.45
4.97
e9/l
0.29
350
1569
137
323
4.54
53.87
1.4
1.7
—
—
—
0
0
421
1977
2.53
53.29
1.5
1.3
546.25
499.31
titre
0.20
96
435
1380
10798
3.00
53.04
17.4
8.1
84.30
79.10
u/l
2.63
1354
10254
720
4293
2.23
52.24
13.8
6.2
—
—
—
0
0
299
1220
2.78
49.98
1.5
1.4
—
—
—
0
0
665
3916
2.19
48.95
3.1
2.3
3.10
2.83
mg/l
1.68
591
3359
363
1667
2.52
47.59
5.2
2.7
7.16
7.85
umol/l
0.23
325
1477
449
2272
2.36
47.46
3.0
2.2
30.30
29.67
s
1.02
441
2206
972
6732
2.13
45.78
4.6
3.1
206.98
125.23
ug/l
2.63
913
6263
629
3703
2.15
45.54
6.9
4.2
87.81
88.84
%
0.50
619
3628
167
529
3.41
43.12
1.3
1.2
—
—
—
0
0
511
2840
2.17
42.26
3.6
3.0
516.87
532.99
mosm/kgh2o
0.95
456
2483
1312
10408
2.44
41.71
7.2
4.4
14.28
12.26
mm/h
4.13
1262
9709
1121
8450
2.09
38.87
8.2
5.3
6.65
6.73
mmol/l
0.57
1081
8032
655
4095
2.01
38.76
4.6
3.4
0.45
0.43
e6/l
0.09
521
3028
734
4790
1.98
38.28
4.9
3.3
39.81
34.20
u/l
1.05
702
4530
727
4756
1.97
37.38
4.7
3.5
92.97
83.61
e6/l
0.06
594
3659
69
131
5.46
34.84
1.4
1.3
0.68
0.41
g/l
0.42
40
98
69
131
5.46
34.84
1.4
1.3
2.80
2.77
g/l
0.02
42
98
69
131
5.46
34.84
1.4
1.3
6.36
6.92
g/l
0.27
41
99
791
5428
1.90
34.27
5.7
4.1
68.31
108.98
e6/l
1.08
621
3840
91
227
4.19
33.10
1.5
1.7
0.76
0.82
g/l
0.15
60
183
67
131
5.29
32.75
1.4
1.3
—
—
—
0
0
917
6685
1.87
32.05
15.9
16.0
1.23
1.27
inr
1.25
802
5591
50
75
6.85
31.97
3.7
2.8
1635.60
1089.44
u/ml
0.62
50
75
521
3174
1.95
31.83
2.3
1.8
1.14
1.27
mg/l
0.75
413
2463
131
435
3.19
31.14
2.3
1.6
0.22
0.24
g/l
1.83
121
415
133
450
3.13
30.63
2.3
1.6
1.10
1.20
g/l
2.76
126
428
885
6473
1.82
29.64
2.6
2.2
94.71
95.05
pmol/l
0.08
542
3466
529
3304
1.90
29.55
3.6
2.7
6.59
5.56
e6/l
0.30
484
2998
282
1413
2.21
28.99
2.6
2.2
352.92
376.49
nmol/l
1.23
269
1310
643
4311
1.82
28.38
2.2
1.7
20.50
20.38
nmol/l
0.07
578
3644
272
1358
2.21
28.16
11.3
7.6
10.53
9.90
mmol/l
0.71
261
1305
723
5051
1.79
27.56
4.3
3.4
2.35
2.35
mmol/l
0.46
672
4584
418
2472
1.93
27.19
2.1
1.7
1241.02
1172.19
nmol/l
0.75
339
1864
143
541
2.80
26.92
3.0
2.2
21.31
21.18
s
0.10
137
491
378
2169
1.97
26.82
2.4
2.1
—
—
—
0
0
114
381
3.14
26.76
2.2
2.3
11.98
12.08
mg/l
0.04
106
354
661
4569
1.76
25.58
3.2
2.6
55.00
78.59
u/l
0.75
625
4244
30
32
9.53
25.34
1.0
1.0
—
—
—
0
0
99
322
3.21
24.31
5.0
3.8
—
—
—
0
0
28
29
9.81
24.15
3.2
1.3
—
—
—
0
0
145
584
2.63
24.12
2.4
1.9
13.95
7.18
iu/ml
1.12
28
137
121
457
2.78
22.81
7.1
4.1
1.53
1.57
mg/l
0.15
114
412
227
1145
2.14
22.61
5.8
3.7
1.21
1.23
mmol/l
2.91
203
975
635
4473
1.69
22.06
3.5
3.2
1867.19
1363.16
ng/l
1.36
550
3854
225
1145
2.12
21.87
4.9
3.8
—
—
—
0
0
388
2382
1.83
21.81
4.2
3.2
3.05
2.35
e6/l
0.54
223
1202
27
31
8.84
21.57
1.1
1.1
—
—
—
0
0
661
4729
1.68
21.50
4.9
2.4
—
—
—
0
0
849
6481
1.66
21.44
3.3
2.5
76.36
77.25
nmol/l
0.40
786
5844
26
7
37.73
20.80
1.2
1.0
—
—
—
0
0
439
2830
1.76
20.79
4.2
4.0
374.86
435.89
ng/l
0.19
353
2231
86
283
3.15
20.71
5.1
4.3
2.42
2.54
mmol/l
0.12
58
188
1128
9326
1.71
20.45
6.4
4.8
243.04
1813.97
e6/l
1.97
28
135
90
308
3.04
20.28
1.3
1.2
—
—
—
0
0
71
211
3.47
20.13
2.5
3.0
—
—
—
0
0
630
4516
1.65
19.92
3.1
2.2
176.81
231.42
u/l
1.20
598
4287
262
1476
1.93
19.03
2.7
2.3
0.20
0.21
g/l
0.59
239
1378
65
190
3.52
18.91
1.8
1.5
—
—
—
0
0
65
190
3.52
18.91
1.8
1.5
—
—
—
0
0
65
190
3.52
18.91
1.8
1.5
—
—
—
0
0
65
190
3.52
18.91
1.8
1.5
—
—
—
0
0
1486
13523
2.35
18.29
35.4
16.4
23.15
25.15
mg/l
1.61
1352
11214
198
1036
2.04
17.71
6.6
3.9
5.23
5.15
kpa
0.44
186
1003
178
896
2.11
17.66
9.3
3.8
24.05
24.21
mmol/l
0.30
178
884
1106
9248
1.63
17.62
4.5
3.4
61.58
49.38
u/l
2.94
1053
8715
609
4442
1.60
17.29
3.7
3.2
—
—
—
0
0
297
1793
1.81
17.22
2.1
1.5
—
—
—
0
0
55
154
3.66
17.07
1.9
1.6
—
—
—
0
0
393
2576
1.70
17.03
4.1
3.1
0.77
1.22
e6/l
1.64
235
1396
186
969
2.04
16.81
1.8
1.3
296.91
228.69
u/ml
0.27
164
900
324
2022
1.75
16.73
1.3
1.2
—
—
—
0
0
851
6743
1.56
16.62
4.8
2.7
—
—
estimate
—
0
0
64
202
3.26
16.53
2.8
2.7
—
—
—
0
0
56
163
3.52
16.42
1.2
1.1
—
—
—
0
0
287
1745
1.79
16.16
1.8
1.7
—
—
—
0
0
242
1401
1.86
15.99
3.0
2.5
35.55
75.12
u/l
0.59
210
1166
923
7496
1.55
15.77
5.0
3.9
0.00
0.00
estimate
0.50
248
1597
189
1013
1.98
15.74
6.8
3.9
7.42
7.42
ph
0.03
155
865
46
121
3.88
15.62
1.1
1.1
—
—
—
0
0
931
7584
1.54
15.62
5.0
3.9
4.57
4.09
estimate
0.03
251
1628
1285
11305
1.69
15.31
44.2
20.3
14.35
13.65
%
37.52
1275
11149
45
119
3.86
15.17
1.2
1.1
83.75
152.00
titre
—
8
20
63
209
3.10
15.01
1.3
1.2
3.88
5.68
u/ml
0.44
33
92
725
5646
1.52
14.64
2.5
2.2
—
—
—
0
0
929
7627
1.52
14.55
5.1
3.9
0.02
0.01
estimate
0.18
229
1525
390
2655
1.62
14.24
1.4
1.3
34.42
31.72
iu/ml
0.16
124
819
226
1331
1.81
14.04
13.2
9.6
—
—
—
0
0
97
417
2.41
14.04
1.4
1.2
3.24
20.26
u/ml
—
5
20
27
27
10.15
13.97
1.3
1.1
—
—
—
0
0
53
166
3.27
13.90
1.7
1.4
—
—
—
0
0
254
1554
1.75
13.86
7.8
3.7
7.36
7.38
ph
3.10
161
895
126
610
2.16
13.78
2.9
1.8
2.15
1.95
ug/l
0.09
113
545
66
237
2.86
13.70
1.1
1.1
—
—
—
0
0
96
416
2.39
13.65
5.4
3.2
1.82
1.97
index
0.12
55
220
244
1499
1.74
13.08
8.2
3.7
1.59
1.83
mmol/l
0.45
220
1276
91
393
2.39
13.05
1.4
1.2
1.49
2.10
u/ml
0.84
12
35
53
173
3.13
13.00
1.7
1.7
35.52
30.74
ng/l
0.11
53
173
61
218
2.87
12.79
1.7
1.4
33.85
31.84
g/l
0.50
51
197
64
237
2.77
12.57
1.1
1.0
—
—
—
0
0
84
357
2.43
12.48
3.5
2.2
118.39
130.38
g/l
3.39
61
292
695
5486
1.47
12.47
5.2
3.9
34.16
63.91
ng/l
1.38
529
3946
24
45
5.40
12.31
2.1
1.6
—
—
—
0
0
24
25
9.73
12.24
1.1
1.4
—
—
—
0
0
754
6068
1.46
12.13
4.2
3.5
6.21
6.23
ph
0.16
416
3382
89
394
2.33
12.08
1.5
1.2
3.81
7.37
u/ml
0.57
19
61
358
2474
1.58
12.02
1.4
1.3
8.81
12.80
u/ml
0.81
110
933
29
68
4.32
11.50
1.3
1.2
—
—
—
0
0
195
1164
1.77
11.50
5.8
4.0
91.86
89.79
ng/l
0.11
170
1023
409
2940
1.53
11.43
3.2
3.0
2.45
2.45
mmol/l
0.20
362
2638
529
4022
1.47
11.19
3.7
3.0
0.00
0.02
—
6
93
190
1135
1.76
11.16
3.0
3.1
253.25
211.73
ng/l
0.54
169
1044
49
168
2.98
11.09
1.6
1.4
231321.06
121832.88
e6/l
0.31
31
94
480
3597
1.48
10.87
4.8
2.3
—
—
—
0
0
1206
10730
1.50
10.81
5.1
4.4
14.85
14.79
pmol/l
0.35
1122
9836
89
414
2.22
10.77
1.2
1.2
74.17
89.33
titre
0.25
12
45
1481
13858
1.90
10.68
36.7
19.6
139.35
139.65
mmol/l
4.50
1460
13599
37
110
3.42
10.58
1.2
1.1
—
—
—
0
0
35
102
3.49
10.32
1.1
1.1
—
—
—
0
0
1481
13881
1.88
10.29
38.3
19.7
3.99
3.98
mmol/l
0.56
1458
13598
72
317
2.33
9.94
1.4
1.2
47.52
60.12
u/ml
0.24
11
31
261
1750
1.59
9.81
9.5
8.6
11.81
12.03
kpa
0.28
250
1691
261
1750
1.59
9.81
9.5
8.6
5.12
5.11
kpa
0.03
250
1688
118
637
1.92
9.59
1.5
1.2
—
—
—
0
0
86
414
2.14
9.58
1.2
1.2
—
1290.00
—
0
13
525
4085
1.42
9.48
4.6
3.4
0.00
0.02
estimate
0.76
201
1269
42
145
2.95
9.43
2.6
2.3
—
—
—
0
0
258
1744
1.57
9.34
9.6
8.7
7.41
7.41
ph
0.37
134
965
244
1642
1.57
8.99
1.3
1.4
—
—
—
0
0
144
848
1.77
8.87
10.5
11.8
15.32
15.95
%
1.81
138
822
1101
9776
1.40
8.75
5.1
4.2
—
4592.05
—
0
22
431
3282
1.43
8.63
1.3
1.3
1.61
1.44
u/ml
0.11
116
888
144
855
1.75
8.62
3.2
3.7
4.53
4.55
pmol/l
0.03
124
761
28
80
3.54
8.54
1.9
1.4
22.60
27.18
umol/l
0.29
28
71
50
200
2.55
8.52
1.6
1.4
1882.50
6008.14
e6/l
0.46
36
140
78
379
2.11
8.51
1.3
1.2
—
—
—
0
0
252
1733
1.54
8.41
9.8
8.6
0.78
0.95
mmol/l
0.23
212
1424
18
37
4.91
8.37
2.1
1.6
—
—
—
0
0
16
17
9.49
8.28
5.6
3.5
—
—
—
0
0
145
875
1.72
8.20
1.3
1.3
19.51
49.94
au/ml
—
7
65
20
46
4.39
8.16
1.5
1.4
—
—
—
0
0
155
960
1.68
7.97
2.3
2.5
22.20
19.26
au/ml
0.13
15
91
45
177
2.59
7.96
1.8
2.4
1.62
0.99
g/24h
0.73
28
104
601
4895
1.36
7.93
5.0
4.2
11.95
8.57
mg/mmol
1.09
382
3124
18
39
4.66
7.88
5.9
3.8
—
—
—
0
0
622
5098
1.36
7.87
4.1
3.5
7.22
7.55
mmol/l
1.04
518
4321
401
3070
1.41
7.66
1.9
1.8
20659138.44
34498077.38
pmol/l
0.26
334
2548
17
24
7.15
7.48
3.8
2.3
39.59
107.21
u/l
0.47
17
24
254
1797
1.49
7.37
2.6
2.5
164.34
123.58
ug/g
0.66
199
1445
227
1570
1.52
7.34
10.2
9.1
94.33
95.53
%
1.45
217
1526
503
4024
1.36
7.31
1.6
1.4
—
—
—
0
0
40
155
2.62
7.31
1.5
2.2
—
—
—
0
0
44
180
2.49
7.20
1.4
1.4
441.06
337.64
pmol/l
0.66
36
155
42
169
2.53
7.12
3.0
1.4
—
—
—
0
0
27
86
3.18
7.00
1.5
1.3
7.36
7.38
ph
0.22
21
59
47
202
2.37
6.93
1.3
1.3
0.16
0.43
nmol/l
—
7
16
121
732
1.71
6.80
1.5
1.2
—
—
—
0
0
193
1310
1.54
6.80
7.9
3.1
4.47
4.51
kpa
0.14
187
1273
81
434
1.91
6.79
1.4
1.5
286.38
268.99
ug/g
0.30
50
262
41
167
2.49
6.79
1.7
1.4
—
—
—
0
0
77
406
1.94
6.77
1.7
1.5
9.89
9.11
u/l
0.19
58
324
120
726
1.71
6.75
7.5
4.0
—
—
—
0
0
581
4797
1.33
6.73
4.1
3.6
62.70
47.12
mg/l
0.94
396
3156
1490
14212
1.69
6.71
24.4
12.2
26.42
26.04
u/l
0.35
1470
13819
210
1458
1.51
6.65
10.3
9.6
116.21
120.82
g/l
2.28
203
1429
20
54
3.74
6.64
1.1
1.1
—
—
—
0
0
41
169
2.46
6.63
1.2
1.2
—
—
nmol/l
—
0
0
261
1897
1.45
6.56
1.4
1.3
—
—
—
0
0
62
306
2.07
6.56
3.3
1.5
—
—
—
0
0
45
197
2.32
6.39
1.6
1.4
48.66
74.46
mu/l
0.40
40
179
15
23
6.57
6.34
5.1
2.2
1.47
2.93
%
0.94
15
23
16
39
4.13
6.09
1.3
1.6
74.39
100.23
nmol/24h
0.68
16
39
56
274
2.08
6.08
3.0
3.1
14.39
8.71
pmol/l
0.44
56
274
39
167
2.37
5.84
1.7
1.4
274.32
278.73
mosm/kgh2o
0.60
34
122
511
4210
1.31
5.82
5.1
4.0
0.00
0.01
estimate
1.54
229
1481
101
609
1.70
5.78
2.2
1.7
0.33
0.34
mg/l
0.10
47
288
39
168
2.35
5.77
1.3
1.3
0.18
0.29
nmol/l
0.49
33
132
18
50
3.63
5.76
2.4
2.6
0.63
0.60
mmol/l
0.68
18
50
73
402
1.85
5.68
7.9
2.7
62.67
60.62
%
0.33
73
390
17
46
3.72
5.65
1.8
1.6
—
—
—
0
0
97
587
1.69
5.49
2.5
2.8
—
—
—
0
0
20
62
3.25
5.45
1.8
2.2
63.63
55.11
ug/l
0.23
20
62
37
161
2.33
5.37
12.1
1.7
10.51
10.84
%
0.18
37
161
39
174
2.27
5.35
1.5
1.2
—
—
—
0
0
1347
12695
1.38
5.27
6.4
5.4
1.92
1.93
mu/l
0.11
1253
11720
55
283
1.98
5.25
1.7
1.3
55.98
59.42
mmol/l
0.27
44
233
39
177
2.23
5.15
1.2
1.2
—
—
—
0
0
28
110
2.57
5.06
1.4
1.4
—
—
—
0
0
25
93
2.71
5.02
1.4
1.3
—
—
—
0
0
194
1402
1.44
5.01
1.8
1.5
—
—
—
0
0
36
160
2.28
5.00
1.1
1.1
—
—
—
0
0
14
28
5.03
4.94
1.9
1.9
—
—
—
0
0
19
61
3.14
4.92
1.5
1.8
40.06
40.01
g/l
0.01
19
61
29
118
2.48
4.89
1.2
1.1
112.41
106.74
pmol/l
0.25
29
118
165
1165
1.46
4.81
1.2
1.2
—
—
—
0
0
1490
14347
1.55
4.79
42.1
21.4
80.61
78.16
umol/l
1.88
1477
14191
206
1525
1.40
4.65
3.1
4.3
25.87
17.95
ug/l
0.20
166
1240
41
199
2.09
4.62
1.2
1.2
—
—
—
0
0
1450
13904
1.45
4.56
26.1
14.8
—
—
—
0
0
419
3457
1.29
4.54
4.3
3.8
—
0.14
—
0
36
69
1132
0.59
4.43
1.3
1.4
—
—
—
0
0
103
676
1.56
4.27
1.4
1.4
22.26
26.67
iu/l
0.82
88
574
35
165
2.15
4.27
9.7
6.9
7.38
7.36
mmol/l
0.01
28
141
13
29
4.51
4.25
1.8
1.5
—
185.33
—
0
6
26
108
2.43
4.23
1.1
1.6
14.30
13.66
umol/l
0.13
26
101
9
13
6.95
4.16
2.8
1.8
—
—
—
0
0
35
167
2.12
4.15
1.8
1.6
52.77
60.13
%
0.42
23
107
650
5697
1.24
4.12
5.0
3.9
0.00
0.03
estimate
4.51
218
1329
14
43
3.28
3.91
1.4
1.3
100.94
36.78
ug/l
—
8
19
17
425
0.39
3.84
33.4
10.4
—
—
—
0
0
92
1364
0.65
3.83
2.2
2.0
3.52
3.51
ratio
0.03
76
1078
12
28
4.31
3.82
2.3
2.4
15.03
17.76
umol/l
0.43
12
28
57
332
1.74
3.79
3.5
1.6
275.33
500.68
e6/l
0.26
45
255
57
332
1.74
3.79
4.9
2.4
—
—
—
0
0
39
203
1.94
3.69
2.4
2.0
—
—
—
0
0
22
91
2.44
3.64
10.2
3.7
0.68
0.91
index
0.98
22
91
56
329
1.73
3.62
3.5
1.5
9.90
39.09
e6/l
0.83
40
243
33
163
2.05
3.61
1.1
1.2
—
—
—
0
0
89
589
1.54
3.60
8.8
4.0
24.80
24.88
mmol/l
0.09
83
553
565
4936
1.22
3.57
4.4
3.7
—
0.76
—
0
17
25
112
2.25
3.49
1.2
1.4
2.31
2.00
mmol/l
0.35
20
105
57
342
1.69
3.44
2.8
1.4
3.68
3.76
mmol/l
0.20
51
326
25
113
2.23
3.42
1.4
1.1
—
—
—
0
0
179
1365
1.35
3.39
2.5
2.1
0.00
0.02
estimate
0.78
36
277
12
32
3.77
3.39
1.2
1.2
—
—
—
0
0
7
10
7.02
3.36
5.0
2.1
255.71
152.70
ug/g
—
7
10
132
959
1.41
3.36
1.3
1.2
44.44
146.60
u/ml
6.37
39
384
21
89
2.38
3.32
1.3
1.8
—
—
—
0
0
17
65
2.63
3.30
1.7
3.2
86.17
91.44
umol/l
—
6
39
59
363
1.65
3.25
2.5
1.7
—
—
—
0
0
18
72
2.52
3.21
1.2
1.6
—
—
—
0
0
62
388
1.62
3.20
1.6
2.0
3.81
18.93
iu/l
0.52
24
160
24
110
2.20
3.19
1.7
2.4
601.71
614.61
ml
0.05
14
70
74
484
1.55
3.18
1.6
1.6
12.83
12.87
u/ml
0.00
14
116
11
29
3.81
3.18
1.3
1.2
—
—
—
0
0
21
91
2.33
3.18
1.1
1.0
—
—
—
0
0
176
1357
1.33
3.11
7.1
4.2
7.38
7.36
ph
3.88
148
980
20
86
2.34
3.08
1.6
2.3
511.33
492.12
min
0.32
12
59
99
694
1.45
3.07
2.8
2.1
0.00
1.22
estimate
0.51
27
209
16
62
2.60
3.04
1.3
1.1
42.25
218.61
ng/l
—
8
18
5
5
10.03
2.98
1.0
1.0
—
—
—
0
0
5
5
10.03
2.98
1.0
1.0
—
—
—
0
0
5
5
10.03
2.98
1.0
1.0
—
—
—
0
0
5
5
10.03
2.98
1.0
1.0
—
—
—
0
0
5
5
10.03
2.98
1.0
1.0
—
—
—
0
0
38
213
1.80
2.93
6.2
5.5
397.75
352.30
umol/l
1.10
32
191
1364
13113
1.27
2.92
5.9
5.2
6.11
5.97
mmol/l
2.54
1261
11991
17
70
2.44
2.88
2.2
1.6
—
—
—
0
0
6
9
6.69
2.87
1.3
1.3
—
—
—
0
0
64
416
1.56
2.86
1.2
1.3
180.75
232.95
miu/ml
0.61
23
198
28
143
1.98
2.86
1.1
1.1
—
—
—
0
0
69
1015
0.67
2.81
1.8
1.7
3.16
3.47
mmol/l
1.78
52
729
29
152
1.92
2.76
8.8
3.3
13.00
11.25
index
0.62
22
91
78
535
1.48
2.73
3.4
3.8
326.20
308.44
mg/l
0.09
45
237
29
153
1.91
2.71
2.3
2.2
17.77
6.53
umol/l
0.64
16
115
1333
12809
1.24
2.69
7.7
6.6
39.75
39.43
mmol/mol
0.59
1246
11985
8
19
4.23
2.68
1.0
1.2
—
—
—
0
0
22
106
2.09
2.63
1.0
1.0
—
—
—
0
0
12
41
2.94
2.62
1.3
1.4
26.08
28.44
s
0.90
12
41
8
20
4.01
2.57
2.8
1.0
—
—
—
0
0
8
20
4.01
2.57
2.8
1.0
—
—
—
0
0
8
20
4.01
2.57
2.8
1.0
—
—
—
0
0
1503
14679
1.38
2.56
52.8
25.0
248.06
248.96
e9/l
0.13
1480
14388
5
7
7.16
2.55
1.2
1.0
36.30
35.40
s
—
5
7
1503
14681
1.38
2.54
52.7
24.9
92.10
91.15
fl
9.02
1489
14529
14
56
2.51
2.53
2.3
1.3
—
—
—
0
0
10
31
3.24
2.52
2.3
1.9
—
—
—
0
0
36
209
1.74
2.51
1.7
1.5
0.24
0.33
nmol/l
0.87
29
167
1503
14684
1.38
2.51
53.9
25.5
39.20
40.25
%
11.77
1488
14524
1503
14684
1.38
2.51
52.6
24.8
30.39
30.34
pg
0.48
1488
14530
1503
14684
1.38
2.51
52.8
24.9
4.32
4.48
e12/l
19.57
1473
14349
1503
14686
1.38
2.48
52.9
25.0
11.33
6.79
e9/l
27.00
1474
14343
7
16
4.39
2.47
5.1
10.9
4.97
5.31
mmol/l
—
7
16
1503
14688
1.37
2.46
53.2
25.1
129.67
134.80
g/l
27.08
1488
14535
152
1191
1.31
2.43
2.9
2.3
12.06
12.77
nmol/l
0.49
132
1069
57
376
1.53
2.43
1.8
1.7
8487.08
14234.33
e6/l
0.92
39
274
51
330
1.56
2.37
2.4
2.4
96.77
99.04
ug/min
0.02
30
199
110
826
1.36
2.36
6.9
2.6
1.61
1.21
%
1.74
110
821
7
17
4.13
2.36
2.0
1.7
—
—
—
0
0
79
571
1.40
2.16
2.9
3.5
1363.18
2664.55
u/ml
0.26
72
495
63
437
1.46
2.15
2.6
1.9
—
—
—
0
0
28
159
1.77
2.14
5.0
1.6
—
—
—
0
0
97
727
1.36
2.13
2.6
2.4
—
—
—
0
0
23
124
1.87
2.07
1.8
1.5
26.32
30.07
%
0.15
13
79
95
714
1.35
2.06
4.0
3.6
1.02
1.02
ratio
0.47
87
660
7
20
3.51
2.05
1.7
3.7
—
—
—
0
0
66
467
1.43
2.04
2.5
1.8
—
—
—
0
0
66
468
1.43
2.02
2.5
1.8
—
—
—
0
0
22
118
1.88
2.02
2.4
2.0
1.36
1.69
u/field
0.30
11
64
63
443
1.44
2.02
2.2
2.1
9643.79
5297.13
u/l
0.24
21
186
66
470
1.42
1.98
2.6
1.8
—
—
—
0
0
7
21
3.34
1.96
1.3
1.4
—
—
—
0
0
152
1228
1.26
1.96
1.7
1.7
—
—
—
0
0
60
421
1.44
1.95
6.5
7.4
1.16
1.37
mmol/l
1.84
48
374
38
245
1.56
1.85
1.4
1.1
—
—
—
0
0
21
115
1.84
1.83
2.3
2.6
31.57
33.08
mg/l
0.05
14
84
7
23
3.05
1.80
1.6
3.7
—
—
—
0
0
14
67
2.10
1.76
4.2
2.6
—
—
—
0
0
14
67
2.10
1.76
1.0
1.0
1850.50
1551.12
miu/ml
0.42
14
67
24
139
1.74
1.76
1.6
1.3
19146.08
169227.84
e6/l
1.26
13
93
8
30
2.67
1.72
8.0
7.1
6.89
5.22
kpa
—
8
30
7
24
2.92
1.72
2.1
1.5
—
—
—
0
0
5
13
3.85
1.71
1.2
1.3
—
—
—
0
0
64
468
1.38
1.69
2.6
1.8
—
—
—
0
0
66
486
1.37
1.67
1.7
1.7
275.83
301.04
mu/l
0.18
61
445
17
90
1.90
1.65
1.9
1.7
93.24
108.01
ng/l
0.34
17
90
24
142
1.70
1.65
2.4
2.4
—
—
—
0
0
5
14
3.58
1.61
1.0
1.0
18.62
18.76
g/l
—
5
14
56
405
1.40
1.59
1.3
1.2
—
—
—
0
0
630
5843
1.13
1.59
2.2
1.9
1.52
1.36
mmol/l
3.14
533
4930
7
26
2.70
1.58
1.4
1.0
—
—
—
0
0
30
191
1.58
1.57
1.7
1.8
—
—
—
0
0
41
284
1.46
1.48
6.7
3.9
29.37
28.00
mg/l
0.10
31
201
36
244
1.49
1.45
1.4
1.1
—
—
—
0
0
47
646
0.72
1.44
1.5
1.7
—
—
—
0
0
6
22
2.73
1.43
1.0
1.2
2.31
1.87
umol/24h
—
6
22
16
88
1.83
1.41
1.3
1.2
—
—
—
0
0
9
40
2.26
1.40
1.1
2.3
—
—
—
0
0
115
940
1.24
1.40
1.2
1.3
—
—
—
0
0
6
23
2.61
1.37
1.0
1.1
—
—
—
0
0
135
1126
1.22
1.36
3.5
2.6
6.07
6.08
ph
0.05
98
775
15
83
1.81
1.31
1.5
1.1
0.61
0.51
ratio
—
9
50
32
460
0.69
1.29
1.0
1.1
1.47
1.54
g/l
1.19
32
460
41
294
1.40
1.27
1.6
1.5
104.05
227.13
pmol/l
1.31
41
289
29
423
0.68
1.26
1.0
1.1
0.72
0.67
ratio
—
6
51
41
295
1.40
1.25
7.0
8.7
11.06
11.42
mmol/l
0.26
36
270
41
295
1.40
1.25
7.0
8.7
105.53
105.36
mmol/l
0.07
36
270
35
481
0.72
1.12
1.1
1.2
0.93
0.90
g/l
0.36
35
481
22
143
1.55
1.11
1.0
1.2
—
—
—
0
0
8
41
1.96
1.09
1.0
1.1
—
—
—
0
0
8
41
1.96
1.09
1.0
1.1
—
—
—
0
0
8
41
1.96
1.09
1.0
1.1
—
—
—
0
0
83
677
1.24
1.08
5.7
5.5
1.94
1.58
%
1.25
77
643
7
33
2.13
1.05
1.4
1.1
—
—
—
0
0
82
671
1.23
1.04
2.2
2.0
—
—
—
0
0
109
921
1.20
1.01
8.6
7.5
25.15
24.36
mmol/l
1.17
102
884
19
123
1.55
0.99
1.1
1.3
0.07
1.06
u/ml
—
8
67
18
115
1.57
0.99
1.6
1.3
9.14
8.84
mmol/l
0.16
18
110
44
335
1.32
0.99
2.2
1.9
180.38
204.77
pmol/l
1.13
37
318
29
206
1.42
0.99
1.4
1.2
—
—
—
0
0
6
27
2.23
0.93
1.2
3.1
—
—
—
0
0
16
241
0.66
0.87
1.8
1.5
—
—
—
0
0
138
1208
1.16
0.87
2.3
2.4
7.09
7.34
ug/l
0.07
116
1086
6
30
2.00
0.87
2.3
1.6
—
—
—
0
0
15
96
1.57
0.84
2.7
2.6
8.25
8.36
mmol/l
0.04
15
96
13
200
0.65
0.80
1.1
1.0
20.84
2.86
u/ml
—
5
101
31
233
1.34
0.79
1.1
1.3
—
—
—
0
0
16
235
0.68
0.79
1.8
1.4
—
—
—
0
0
11
66
1.67
0.78
1.5
1.3
151.27
172.99
mmol/24h
0.67
11
66
44
350
1.26
0.76
4.5
4.5
—
—
—
0
0
18
124
1.46
0.75
6.5
5.7
18.33
59.78
u/ml
—
7
44
9
59
1.53
0.68
1.3
3.1
—
—
—
0
0
27
347
0.77
0.62
1.4
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
2.3
—
3.34
—
0
8
8
52
1.54
0.59
1.0
1.1
—
—
—
0
0
10
64
1.57
0.58
1.3
2.9
—
—
—
0
0
34
273
1.25
0.58
1.1
1.1
0.87
2.94
u/ml
1.48
21
152
39
319
1.23
0.57
3.4
3.4
0.78
0.83
nmol/l
0.27
31
263
1292
12728
1.08
0.57
4.8
4.3
1.43
1.29
mmol/l
7.15
1207
11676
71
616
1.16
0.56
6.2
5.8
0.88
0.87
%
0.09
66
582
25
195
1.29
0.54
1.6
1.4
34.16
23.70
u/l
0.68
18
161
7
46
1.52
0.48
1.1
1.0
—
3.04
—
0
5
1372
13574
1.07
0.45
6.2
5.9
2.53
2.67
mmol/l
7.87
1291
12603
20
252
0.79
0.43
1.4
1.7
—
—
—
0
0
44
509
0.86
0.41
1.7
1.6
908.73
989.95
mu/l
0.32
39
413
0
15
0.00
0.41
0.0
1.0
—
257.60
—
0
5
0
16
0.00
0.41
0.0
1.6
—
6.78
—
0
6
38
324
1.18
0.40
2.5
1.7
—
—
—
0
0
5
34
1.47
0.40
1.0
1.0
—
—
—
0
0
14
106
1.32
0.39
1.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
0.25
—
0
6
73
656
1.12
0.38
1.1
1.1
—
—
—
0
0
161
1719
0.93
0.37
4.4
5.0
31.64
32.34
%
0.34
118
1138
5
37
1.35
0.37
1.2
1.6
7.74
7.60
mmol/l
—
5
37
506
5199
0.96
0.30
3.9
3.2
—
—
—
0
0
166
1571
1.06
0.30
1.6
1.7
—
—
—
0
0
488
4756
1.04
0.27
5.4
5.6
2.08
2.64
ug/l
1.29
436
4280
1115
11265
0.97
0.25
45.5
21.2
329.77
332.26
g/l
14.45
1109
11198
1347
13381
1.04
0.23
5.6
5.2
4.37
4.58
mmol/l
11.91
1272
12476
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
1338
13310
1.03
0.17
5.5
5.1
1.34
1.45
mmol/l
18.56
1257
12320
127
1320
0.96
0.16
1.5
1.5
—
—
—
0
0
20
222
0.90
0.13
1.1
1.1
2.89
1.72
u/ml
0.16
12
115
329
3352
0.98
0.13
5.0
4.1
1.02
1.02
kg/l
1.54
252
2233
14
159
0.88
0.13
2.5
2.6
—
—
—
0
0
29
312
0.93
0.11
1.1
1.2
—
—
—
0
0
52
494
1.05
0.11
1.1
1.1
—
—
—
0
0
14
157
0.89
0.11
1.5
2.2
—
—
—
0
0
12
105
1.14
0.11
2.2
1.4
93.92
81.12
umol/l
0.52
12
105
5
47
1.06
0.09
1.2
1.3
0.00
0.06
estimate
—
5
47
5
63
0.79
0.08
2.0
1.3
12.00
9.59
mm/h
—
5
63
6
72
0.83
0.07
1.0
1.1
—
—
—
0
0
10
89
1.12
0.07
3.0
2.8
15.58
16.22
%
—
10
89
72
700
1.03
0.06
5.5
4.5
36.95
36.91
°c
0.67
67
695
22
229
0.96
0.03
1.0
1.1
0.05
0.97
u/ml
—
10
98
286
2872
0.99
0.01
3.2
3.3
0.76
0.76
ug/l
0.03
191
1885
23
236
0.97
0.00
1.0
1.1
2.98
5.15
u/ml
0.59
12
122
39
394
0.99
0.00
1.1
1.1
—
—
—
0
0
15
152
0.99
0.00
2.4
1.5
584.00
324.77
mu/l
—
10
124
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
365.13
—
0
8
7
78
0.90
-0.00
1.9
1.3
184.30
161.93
pmol/l
—
7
78
0
7
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
4.72
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_WHITEBLOODCELLNAS and mortality.

Females

Parameter HR [95% CI] p-value
D3_WHITEBLOODCELLNAS 2.642 [2.33, 3.0] < 0.001
Birth year 0.991 [0.98, 1.0] 0.036

During the follow-up period (1.1.1998 — 31.12.2019), 1292 out of 4517 females with D3_WHITEBLOODCELLNAS died.

Males

Parameter HR [95% CI] p-value
D3_WHITEBLOODCELLNAS 2.552 [2.21, 2.94] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 1504 out of 4168 males with D3_WHITEBLOODCELLNAS died.

Mortality risk

Mortality risk for people of age

years, who have D3_WHITEBLOODCELLNAS.

N-year risk Females Males
1 0.209% 0.51%
5 1.386% 2.595%
10 3.304% 6.39%
15 6.409% 12.203%
20 10.995% 20.185%

Relationships between endpoints

Index endpoint: D3_WHITEBLOODCELLNAS – Other and unspecified disorders of white blood cells

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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