Other/unspecified disorders of vestibular function

H8_VESTIFUNCNAS

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H81.8, H81.9
  • Hospital discharge: ICD-9 386[8-9]
  • Cause of death: ICD-10 H81.8, H81.9
  • Cause of death: ICD-9 386[8-9]

2 out of 7 registries used, show all original rules.

1838

4. Check minimum number of events

None

1838

5. Include endpoints

None

1838

6. Filter based on genotype QC (FinnGen only)

1609

Control definitions (FinnGen only)

Control exclude
H8_INNER

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10780 6802 3882
Only index persons 9261 5920 3341
Unadjusted period prevalence (%)
Whole population 0.16 0.19 0.11
Only index persons 0.19 0.22 0.13
Median age at first event (years)
Whole population 64.51 66.08 61.73
Only index persons 62.36 63.66 60.06

-FinnGen-

Key figures

All Female Male
Number of individuals 1609 1030 579
Unadjusted period prevalence (%) 0.33 0.37 0.27
Median age at first event (years) 63.03 62.25 64.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1691
Matched controls
16910
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
10.4
307.7
443
556
H81.8
ICD-10 Finland
Other disorders of vestibular function
370.4
307.7
304
10
H81.0
ICD-10 Finland
Ménière disease
78.3
307.7
182
26
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
1483.5
307.7
1226
30
R42
ICD-10 Finland
Dizziness and giddiness
9.0
307.7
1033
2514
H81.3
ICD-10 Finland
Other peripheral vertigo
27.8
253.5
175
70
N07CA01
ATC
betahistine; oral
8.1
239.9
366
555
N17
ICPC
Vertigo/dizziness
4.6
159.7
486
1368
H81.2
ICD-10 Finland
Vestibular neuronitis
168.1
133.5
139
9
DFF59
NOMESCO Finland
Other assessment of balance
27.9
132.0
90
34
AA1AD
NOMESCO Finland
CT of head and brain
3.4
130.0
822
3710
3868X
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other disorders of labyrinth
+∞
124.5
118
*
DFF00
NOMESCO Finland
Pure tone audiometry
3.8
94.9
337
1030
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
50.4
84.5
49
10
3869X
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Unspecified vertiginous syndromes and labyrinthine disorders
+∞
72.4
69
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.0
68.6
376
1480
G44.2
ICD-10 Finland
Tension-type headache
2.8
54.7
329
1347
R51.80
ICD-10 Finland
Headache
2.6
50.2
351
1545
H81.4
ICD-10 Finland
Vertigo of central origin
17.8
49.0
40
23
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.9
42.8
224
846
R53
ICD-10 Finland
Malaise and fatigue
2.1
40.3
541
3108
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.2
39.2
109
274
UDC00
NOMESCO Finland
Ear microscopy
3.1
38.5
179
631
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
36.1
676
4331
7804A
ICD-9 Finland
General symptoms, Dizziness and giddiness
6.7
35.0
56
86
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
7.9
32.9
45
58
R11
ICD-10 Finland
Nausea and vomiting
2.5
30.7
212
915
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
29.1
553
3503
A02BC02
ATC
pantoprazole; systemic
1.9
29.0
1224
9837
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
7.3
28.5
42
59
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
4.4
28.3
72
169
M79.6
ICD-10 Finland
Pain in limb
1.8
28.2
804
5737
H82
ICPC
Vertiginous syndrome
5.1
27.6
59
120
D09
ICPC
Nausea
3.2
26.5
111
367
N05AB04
ATC
prochlorperazine; systemic, rectal
4.4
26.4
67
157
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
26.0
156
627
DFF50
NOMESCO Finland
Electronystagmography
40.8
25.9
32
8
L17
ICPC
Foot/toe symptom/complaint
1.8
25.4
569
3759
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
25.4
885
6610
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.4
24.8
181
799
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
24.6
318
1762
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
24.4
230
1132
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.9
24.3
367
2141
A11
ICPC
Chest pain NOS
2.3
24.3
194
890
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
23.9
404
2443
R55
ICD-10 Finland
Syncope and collapse
2.1
23.5
241
1224
A04
ICPC
Weakness/tiredness general
1.9
23.5
325
1841
A28
ICPC
Limited function/disability NOS
1.9
23.4
394
2378
N01
ICPC
Headache
2.2
23.0
204
978
PA6AD
NOMESCO Finland
CT of neck arteries
3.2
22.8
95
313
R4110
NOMESCO Finland
Physiotherapy
1.7
22.1
512
3388
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
21.9
388
2374
DC1AD
NOMESCO Finland
Temporalbone CT
7.0
21.7
33
48
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
21.4
170
777
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.4
21.1
42
80
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
20.9
164
746
H29
ICPC
Ear symptom/complaint other
2.0
20.3
238
1267
R07.3
ICD-10 Finland
Other chest pain
2.1
20.3
216
1110
N02BE01
ATC
paracetamol; systemic, rectal
2.2
20.3
1533
13776
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
20.2
336
2010
S06.0
ICD-10 Finland
Concussion
2.1
20.2
210
1070
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
20.0
755
5632
M79.1
ICD-10 Finland
Myalgia
1.9
19.7
278
1577
A01
ICPC
Pain general/multiple sites
2.1
19.2
209
1082
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.2
18.8
170
820
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
18.4
305
1818
M54.5
ICD-10 Finland
Low back pain
1.6
18.4
618
4457
Z71.8
ICD-10 Finland
Other specified counselling
1.6
18.4
571
4041
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
18.3
1147
9565
N03AX16
ATC
[U] pregabalin
1.7
17.9
412
2696
M03BX02
ATC
tizanidine; oral
1.6
17.9
982
7916
N06AX11
ATC
mirtazapine; oral
1.6
17.8
600
4323
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
17.7
397
2580
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.4
17.5
122
526
N02AX02
ATC
tramadol; systemic, rectal
1.6
17.5
731
5532
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
17.4
583
4188
Z3226
NOMESCO Finland
Physiotherapist
1.8
17.4
324
1998
L01
ICPC
Neck symptom/complaint
1.8
17.4
286
1700
R52.9
ICD-10 Finland
Pain, unspecified
2.0
17.3
196
1029
L03
ICPC
Low back symptom/complaint
1.6
17.2
498
3452
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
17.0
671
5000
N03AX12
ATC
[U] gabapentin; oral
1.8
17.0
293
1766
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.7
16.9
90
340
C07AB07
ATC
bisoprolol; oral
1.5
16.9
872
6895
G43.9
ICD-10 Finland
Migraine, unspecified
2.6
16.9
104
423
A02BC05
ATC
esomeprazole; systemic
1.6
16.8
686
5147
B01AC04
ATC
clopidogrel; oral
1.8
16.8
311
1913
H93.1
ICD-10 Finland
Tinnitus
2.3
16.8
131
594
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
16.6
321
1997
R03AC02
ATC
salbutamol; inhalant
1.5
16.5
905
7236
R06.0
ICD-10 Finland
Dyspnoea
1.6
16.3
498
3489
H01
ICPC
Ear pain/earache
2.0
16.3
203
1101
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
16.2
343
2189
G43.8
ICD-10 Finland
Other migraine
4.6
15.9
37
81
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
15.9
283
1719
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
15.5
513
3655
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.9
15.4
222
1262
H02AB06
ATC
prednisolone; systemic
1.5
15.1
797
6276
Z01.2
ICD-10 Finland
Dental examination
1.5
15.1
724
5589
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
15.0
389
2611
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
15.0
695
5327
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
14.9
213
1208
R20.2
ICD-10 Finland
Paraesthesia of skin
2.2
14.9
128
604
K30
ICD-10 Finland
Functional dyspepsia
1.9
14.8
204
1144
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.1
14.7
150
756
3861A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other and unspecified peripheral vertigo
+∞
14.6
14
*
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
14.5
354
2337
L28
ICPC
Limited function/disability (L)
1.6
14.5
371
2479
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
14.4
859
6911
L29
ICPC
Musculoskeletal sympt/complt other
2.0
14.3
170
906
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
14.1
83
330
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
14.1
198
1115
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.8
14.1
69
250
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
3.4
14.0
51
155
SFA20
NOMESCO Finland
Two-surface restoration
1.5
14.0
893
7270
D01
ICPC
Abdominal pain/cramps general
1.8
14.0
212
1225
N06AB10
ATC
escitalopram; oral
1.7
13.8
315
2044
U07
ICPC
Urine symptom/complaint other
2.0
13.7
165
883
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
13.6
713
5568
R02
ICPC
Shortness of breath/dyspnoea
1.7
13.6
253
1551
M54.2
ICD-10 Finland
Cervicalgia
2.0
13.6
144
737
R05
ICPC
Cough
1.6
13.5
417
2910
U02
ICPC
Urinary frequency/urgency
1.7
13.3
273
1719
I95.1
ICD-10 Finland
Orthostatic hypotension
2.4
13.3
89
377
C10AA05
ATC
atorvastatin; oral
1.5
13.2
720
5658
K02.1
ICD-10 Finland
Caries of dentine
1.5
13.2
892
7309
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
13.1
152
803
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
13.0
116
555
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
13.0
659
5099
J01MA02
ATC
ciprofloxacin; systemic
1.5
13.0
643
4951
N06AX21
ATC
duloxetine; oral
1.8
13.0
209
1228
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
12.9
489
3565
A02BC01
ATC
omeprazole; systemic
1.5
12.9
458
3293
S29
ICPC
Skin symptom/complaint other
1.6
12.9
353
2392
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
12.6
219
1317
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
12.6
329
2204
SFA10
NOMESCO Finland
One-surface restoration
1.5
12.5
840
6844
Z2221
NOMESCO Finland
Medical doctor
1.5
12.5
443
3182
R06AE53
ATC
cyclizine, combinations; systemic
5.1
12.4
26
52
TAB00
NOMESCO Finland
Lumbar puncture
2.4
12.3
83
353
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.3
12.3
89
391
A02BC03
ATC
lansoprazole; oral
1.5
12.2
480
3518
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.9
12.2
58
207
A29
ICPC
General symptom/complaint other
1.7
12.1
243
1519
R05
ICD-10 Finland
Cough
1.6
12.1
353
2425
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
12.0
744
5955
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
12.0
417
2976
A97
ICPC
No disease
1.6
12.0
341
2327
R01AD09
ATC
mometasone; nasal
1.4
12.0
692
5469
D02
ICPC
Abdominal pain epigastric
2.1
11.9
115
568
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
11.9
130
672
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.9
11.9
55
193
L12
ICPC
Hand/finger symptom/complaint
1.6
11.9
284
1858
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
11.9
369
2569
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
11.9
297
1965
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
11.9
126
645
L15
ICPC
Knee symptom/complaint
1.5
11.9
424
3044
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
11.8
222
1362
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
11.8
1126
9750
N03AX09
ATC
lamotrigine; oral
2.5
11.8
76
317
M79.7
ICD-10 Finland
Fibromyalgia
2.6
11.8
67
263
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
11.7
440
3193
M25.5
ICD-10 Finland
Pain in joint
1.5
11.6
521
3915
N05CF01
ATC
zopiclone; oral
1.5
11.5
545
4137
H80.9
ICD-10 Finland
Otosclerosis, unspecified
+∞
11.5
11
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
11.3
286
1896
N05AH04
ATC
quetiapine; oral
1.6
11.3
276
1815
R12
ICD-10 Finland
Heartburn
1.9
11.2
143
780
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
11.2
204
1241
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.6
11.2
63
246
H02
ICPC
Hearing complaint
1.6
11.2
261
1696
H53.2
ICD-10 Finland
Diplopia
2.6
11.2
65
258
J01DB01
ATC
cefalexin; oral
1.5
11.1
1333
11993
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
11.1
305
2061
D19
ICPC
Teeth/gum symptom/complaint
1.5
11.1
465
3443
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.6
11.1
291
1946
DFF15
NOMESCO Finland
Speech audiometry
2.2
11.0
95
449
D83
ICPC
Mouth/tongue/lip disease
4.3
11.0
28
66
J01AA02
ATC
doxycycline; systemic
1.5
11.0
1262
11235
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
11.0
1006
8588
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.1
11.0
107
531
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
10.9
290
1944
UJF32
NOMESCO Finland
Coloscopy
1.5
10.9
434
3180
N06AX16
ATC
venlafaxine; oral
1.7
10.8
222
1394
L86
ICPC
Back syndrome with radiating pain
2.0
10.8
113
576
J01CA04
ATC
amoxicillin; systemic
1.5
10.7
1293
11587
DAX08
NOMESCO Finland
Fitting of hearing aid
2.0
10.7
114
585
R83
ICPC
Respiratory infection other
1.5
10.7
347
2435
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
10.6
131
707
R06.4
ICD-10 Finland
Hyperventilation
3.7
10.4
32
87
F29
ICPC
Eye symptom/complaint other
1.8
10.4
178
1063
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
10.4
401
2916
M48.0
ICD-10 Finland
Spinal stenosis
1.7
10.3
226
1443
Z2445
NOMESCO Finland
Psychologist
2.6
10.3
60
239
K80
ICPC
Cardiac arrhythmia NOS
1.8
10.2
153
878
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
3.0
10.2
45
154
L04
ICPC
Chest symptom/complaint
2.0
10.2
116
609
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
10.2
693
5592
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
10.2
395
2874
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
10.1
57
223
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
10.1
434
3221
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
10.1
217
1380
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
10.0
93
453
D11
ICPC
Diarrhoea
1.7
10.0
183
1114
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.8
10.0
141
795
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.9
9.9
120
643
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
9.9
88
421
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.8
9.9
47
168
Z01.7
ICD-10 Finland
Laboratory examination
1.6
9.9
268
1804
R50.9
ICD-10 Finland
Fever, unspecified
1.6
9.8
241
1582
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
9.8
415
3066
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.3
9.8
76
344
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
1.9
9.8
122
660
N30.0
ICD-10 Finland
Acute cystitis
1.5
9.8
302
2090
P01
ICPC
Feeling anxious/nervous/tense
1.8
9.8
157
920
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
9.8
221
1422
R51
ICD-10 Finland
Headache
2.1
9.8
90
437
J01DA01
ATC
[U] cefalexin
1.4
9.8
975
8366
H02AB04
ATC
methylprednisolone; systemic
1.6
9.8
233
1520
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.5
9.7
431
3213
R74
ICPC
Upper respiratory infection acute
1.4
9.7
458
3456
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
9.6
183
1125
J01FA10
ATC
azithromycin; systemic
1.4
9.6
847
7111
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
9.6
131
730
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
9.6
174
1056
XQ800
NOMESCO Finland
Prick test
2.0
9.6
111
586
H92.0
ICD-10 Finland
Otalgia
2.0
9.6
99
502
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.3
9.5
70
310
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.8
9.5
134
755
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.4
9.5
66
285
P03
ICPC
Feeling depressed
1.8
9.5
133
748
PA7BD
NOMESCO Finland
CT angiography of neck and brain
3.2
9.5
36
113
A02BA02
ATC
ranitidine; systemic
1.5
9.5
319
2250
J02AC01
ATC
fluconazole; systemic
1.4
9.4
594
4713
P29
ICPC
Psychological sympt/compl other
2.0
9.4
107
562
R01AD58
ATC
fluticasone, combinations; nasal
1.5
9.4
348
2503
P01AB01
ATC
metronidazole; oral, rectal
1.4
9.4
620
4959
N03AE01
ATC
clonazepam; systemic
2.0
9.4
95
479
WX402
NOMESCO Finland
General anaesthesia
1.5
9.3
339
2428
D06
ICPC
Abdominal pain localized other
1.8
9.3
143
827
T78.4
ICD-10 Finland
Allergy, unspecified
2.2
9.3
73
333
J01FA06
ATC
roxithromycin; oral
1.4
9.3
620
4968
K24
ICPC
Fear of heart disease
2.6
9.2
51
198
N30.9
ICD-10 Finland
Cystitis, unspecified
1.9
9.2
122
675
R5110, ,
SPAT
1.7
9.2
165
1000
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.8
9.1
135
772
TDA90
NOMESCO Finland
Removal wax from ear
3.5
9.1
31
91
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.0
784
6544
H81
ICD-10 Finland
Disorders of vestibular function
15.7
9.0
14
9
N05BA01
ATC
diazepam; systemic, rectal
1.6
9.0
214
1394
I20.09
ICD-10 Finland
Unstable angina
1.9
9.0
106
564
R00.2
ICD-10 Finland
Palpitations
1.8
9.0
129
732
K02
ICPC
Pressure/tightness of heart
2.6
9.0
49
189
WX290
NOMESCO Finland
Other blockage of nerve
1.4
8.9
665
5417
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
8.9
463
3550
C08CA01
ATC
amlodipine; oral
1.4
8.8
654
5316
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.3
8.8
63
276
M01AH05
ATC
etoricoxib; oral
1.4
8.8
951
8202
Z3231
NOMESCO Finland
Registered nurse
1.4
8.8
424
3203
KMAK, ,
NOMESCO Finland
1.4
8.8
743
6167
SFA30
NOMESCO Finland
Three-surface restoration
1.4
8.8
631
5105
M01AB05
ATC
diclofenac; systemic, rectal
1.4
8.7
1012
8822
N06AX26
ATC
vortioxetine; oral
1.9
8.7
109
592
F41.00
ICD-10 Finland
Moderate panic disorder
3.6
8.7
28
79
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
8.7
442
3371
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.0
8.7
91
465
C07AA05
ATC
propranolol; systemic
1.5
8.7
297
2100
L13
ICPC
Hip symptom/complaint
1.5
8.6
328
2368
L11
ICPC
Wrist symptom/complaint
1.7
8.6
151
908
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.7
8.5
174
1090
R21
ICPC
Throat symptom/complaint
1.5
8.5
277
1936
N06AB04
ATC
citalopram; systemic
1.5
8.5
317
2278
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.2
8.5
33
105
N05BA04
ATC
oxazepam; oral
1.4
8.5
422
3202
XA800
NOMESCO Finland
Neuropsychological investigation
2.3
8.5
65
294
R03DC03
ATC
montelukast; oral
1.5
8.5
252
1729
W19
ICD-10 Finland
Unspecified fall
1.7
8.4
162
999
C01DA14
ATC
isosorbide mononitrate; oral
1.5
8.4
272
1898
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
2.2
8.4
68
314
X15
ICPC
Vaginal symptom/complaint other
2.3
8.4
60
263
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
8.4
333
2423
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
8.4
368
2731
R03BA05
ATC
fluticasone; inhalant
1.5
8.3
273
1911
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
8.3
171
1074
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
8.3
82
410
N06AB06
ATC
sertraline; oral
1.7
8.3
170
1067
N02BF02
ATC
pregabalin; oral
1.9
8.3
112
624
G04CA02
ATC
tamsulosin; oral
1.5
8.2
319
2312
WX892
NOMESCO Finland
Monitored bed care
1.8
8.2
128
745
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.7
8.2
171
1078
R25.2
ICD-10 Finland
Cramp and spasm
2.5
8.2
48
192
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.5
8.2
268
1876
N06AA09
ATC
amitriptyline; systemic
1.7
8.1
161
1003
SDA03
NOMESCO Finland
Periodontal treatment
1.4
8.1
589
4761
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
8.0
1030
9059
H91.9
ICD-10 Finland
Hearing loss, unspecified
1.9
8.0
92
485
M54.6
ICD-10 Finland
Pain in thoracic spine
1.8
8.0
116
660
L05
ICPC
Flank/axilla symptom/complaint
1.8
8.0
110
616
S21
ICPC
Skin texture symptom/complaint
1.5
8.0
244
1682
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.7
8.0
150
920
N19
ICPC
Speech disorder
3.2
8.0
30
94
UKC02
NOMESCO Finland
Cystoscopy
1.5
7.9
243
1677
A23
ICPC
Risk factor NOS
1.7
7.9
146
891
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.4
7.9
402
3059
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.5
7.9
49
202
K29
ICPC
Cardiovascular sympt/complt other
2.0
7.8
78
391
SGC00
NOMESCO Finland
Medication, disinfection of root canals
1.7
7.8
143
870
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.6
7.8
177
1140
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
7.8
314
2290
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.4
7.8
433
3346
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.7
582
4720
M02AA07
ATC
piroxicam; topical
1.4
7.7
570
4609
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.7
7.7
155
968
H13
ICPC
Plugged feeling ear
1.5
7.7
314
2295
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.0
7.7
76
381
R13
ICD-10 Finland
Dysphagia
1.8
7.6
120
701
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
3.6
7.6
24
67
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
7.6
162
1028
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.8
7.5
22
58
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.8
7.5
122
718
N02BF01
ATC
gabapentin; oral
1.6
7.5
167
1069
W22
ICD-10 Finland
Striking against or struck by other object(s)
1.9
7.5
91
489
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
7.5
143
880
C07AB02
ATC
metoprolol; systemic
1.4
7.5
331
2453
K03.64
ICD-10 Finland
Dental calculus supragingival
1.4
7.5
455
3565
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
80.4
7.4
8
*
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
7.4
352
2643
WX002
NOMESCO Finland
Sedation and analgesia
1.4
7.4
303
2215
G04BD12
ATC
mirabegron; oral
1.5
7.4
203
1368
C09CA06
ATC
candesartan; oral
1.4
7.4
375
2851
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
7.4
591
4832
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.1
7.3
65
312
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.3
269
1924
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.4
7.3
15
18
3860A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Ménière's disease
+∞
7.3
7
*
P20
ICPC
Memory disturbance
1.5
7.3
254
1800
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.1
7.3
64
307
S80.0
ICD-10 Finland
Contusion of knee
1.8
7.2
116
681
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
7.2
299
2189
G04CA01
ATC
alfuzosin; oral
1.6
7.2
166
1072
K08.80
ICD-10 Finland
Toothache NOS
1.7
7.2
130
789
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
7.2
196
1317
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.4
7.2
386
2959
WX704
NOMESCO Finland
Intubation
1.7
7.2
125
751
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.2
557
4527
R96
ICPC
Asthma
1.6
7.2
160
1026
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
7.2
385
2952
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
7.1
223
1544
G50.1
ICD-10 Finland
Atypical facial pain
2.9
7.1
33
117
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
7.1
133
815
H02AB07
ATC
prednisone; oral
1.5
7.1
217
1495
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.7
7.1
142
886
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
7.1
184
1224
K85
ICPC
Elevated blood pressure
1.4
7.0
283
2062
F01
ICPC
Eye pain
2.3
7.0
50
220
XF404
NOMESCO Finland
Ambulatory ECG
1.7
7.0
140
874
P74
ICPC
Anxiety disorder/anxiety state
2.1
7.0
64
312
WZA90
NOMESCO Finland
Other medical or dental certificate
1.4
6.9
338
2548
P06
ICPC
Sleep disturbance
1.6
6.9
185
1238
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
6.9
156
1003
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
6.9
280
2041
B01AC07
ATC
dipyridamole; systemic
2.0
6.9
76
396
A13
ICPC
Concern/fear medical treatment
2.6
6.9
39
154
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
6.9
398
3088
R51.81
ICD-10 Finland
Facial pain NOS
2.4
6.8
43
179
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
6.8
172
1137
A98
ICPC
Health maint/preventive medicine
1.7
6.8
1572
15013
U04
ICPC
Incontinence urine
1.7
6.8
110
649
C09CA01
ATC
losartan; oral
1.4
6.7
413
3231
H82
ICD-10 Finland
Vertiginous syndromes in diseases classified elsewhere
16.8
6.7
10
6
K01
ICPC
Heart pain
3.2
6.7
26
83
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
6.7
156
1010
Z97.4
ICD-10 Finland
Presence of external hearing-aid
1.9
6.7
83
450
K05.1
ICD-10 Finland
Chronic gingivitis
1.8
6.7
98
560
EB1AA, ,
SPAT
1.8
6.7
97
553
K07.60
ICD-10 Finland
Snapping jaw
1.9
6.7
76
401
R03BA02
ATC
budesonide; inhalant
1.4
6.7
268
1950
A03
ICPC
Fever
1.5
6.7
226
1591
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
6.6
338
2568
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
3.5
6.6
22
64
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
6.6
106
624
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
2.8
6.6
32
117
M54.1
ICD-10 Finland
Radiculopathy
2.1
6.5
63
313
W17
ICD-10 Finland
Other fall from one level to another
2.1
6.5
59
286
J46
ICD-10 Finland
Status asthmaticus
2.3
6.5
48
214
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
6.5
180
1215
N03AF01
ATC
carbamazepine; oral, rectal
1.9
6.5
80
434
WX110, ,
SPAT
1.9
6.5
83
456
WX320
NOMESCO Finland
Spinalanesthesy
1.4
6.4
388
3025
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.6
6.4
144
924
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.0
6.4
70
364
L02
ICPC
Back symptom/complaint
1.6
6.4
152
990
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.8
6.4
99
576
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.2
6.4
50
229
P76
ICPC
Depressive disorder
1.8
6.4
87
487
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
2.6
6.4
36
142
-1, ,
NOMESCO Finland
1.3
6.4
452
3613
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.6
6.4
170
1137
M01AE02
ATC
naproxen; oral, rectal
1.3
6.4
829
7205
G47.3
ICD-10 Finland
Sleep apnoea
1.4
6.4
320
2422
C03DA01
ATC
spironolactone; oral
1.5
6.4
207
1445
C01CA24
ATC
epinephrine; parenteral
1.8
6.3
89
503
R03BA08
ATC
ciclesonide; inhalant
1.6
6.3
129
809
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.2
6.3
50
230
SPAT1043
SPAT
Audiometry
1.6
6.3
164
1090
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.1
6.3
60
297
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
2.6
6.3
36
143
A02BX02
ATC
sucralfate; oral
2.0
6.3
64
325
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
6.3
107
640
R25.1
ICD-10 Finland
Tremor, unspecified
2.2
6.3
52
244
Z30.0
ICD-10 Finland
General counselling and advice on contraception
2.1
6.3
55
264
38699, ,
ICD-8 Finland
+∞
6.3
6
*
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.4
6.2
41
174
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
6.2
118
726
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.7
6.2
119
734
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.1
6.2
54
258
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
6.2
413
3268
G62.8
ICD-10 Finland
Other specified polyneuropathies
3.7
6.2
19
52
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.1
6.2
25
82
XF600
NOMESCO Finland
Bloodpressure measurement
1.7
6.2
99
582
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.8
6.2
93
537
H81
ICPC
Excessive ear wax
1.4
6.2
280
2082
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
2.3
6.2
44
194
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.1
6.1
52
246
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
2.2
6.1
50
233
D29
ICPC
Digestive symptom/complaint other
2.3
6.1
43
188
J01CA08
ATC
pivmecillinam; oral
1.3
6.1
656
5551
D07AC01
ATC
betamethasone; topical
1.3
6.1
548
4527
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.9
6.1
75
407
N29
ICPC
Neurological sympt/complt other
2.6
6.0
34
134
D12
ICPC
Constipation
2.0
6.0
64
330
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.7
6.0
112
686

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
808
4859
2.27
58.29
2.5
2.2
187.48
234.26
u/l
0.61
781
4585
1236
9067
2.35
52.35
5.5
5.2
6.59
6.75
mmol/l
2.24
1184
8602
567
3067
2.28
51.39
4.8
4.0
291.81
399.25
ng/l
0.39
460
2506
480
2420
2.37
51.30
2.0
2.1
28.59
29.58
s
4.17
467
2353
1071
8065
1.89
33.73
7.8
7.4
1.22
1.21
mmol/l
1.06
948
6939
984
7222
1.87
33.51
6.8
6.7
1.22
1.21
mmol/l
0.99
924
6671
991
7304
1.86
33.14
20.0
16.2
1.28
1.29
inr
0.01
832
6068
1353
11065
2.11
33.01
5.4
4.4
12.51
13.32
mm/h
1.27
1286
10288
1253
10064
1.95
30.83
6.8
5.1
350.38
2388.17
e6/l
2.34
26
151
837
6005
1.78
29.11
5.2
4.0
39.36
143.59
ng/l
0.81
583
4436
713
4908
1.78
28.35
4.3
4.3
7.40
7.40
ph
0.37
520
3557
949
7131
1.75
27.46
2.5
2.2
94.36
95.99
pmol/l
0.47
504
3724
1583
14180
2.82
25.55
24.1
17.4
21.56
25.13
mg/l
5.08
1391
11841
730
5226
1.70
24.06
4.1
3.5
—
—
—
0
0
619
4243
1.72
23.91
3.9
3.3
0.07
0.05
0.10
15
125
586
3957
1.74
23.88
4.5
4.1
87.50
88.64
%
0.48
575
3873
200
950
2.25
23.06
2.7
2.5
21.25
20.81
au/ml
0.03
19
87
934
7187
1.67
22.99
4.7
5.1
36.08
35.25
g/l
4.87
867
6739
1152
9371
1.72
22.94
3.8
3.3
44.66
50.47
u/l
1.69
1081
8756
927
7128
1.67
22.81
7.9
6.5
0.67
0.67
%
0.06
871
6649
927
7129
1.66
22.79
7.5
6.3
57.67
57.87
%
0.21
882
6797
671
4753
1.68
22.62
1.9
1.7
20.49
20.17
nmol/l
0.21
594
3986
927
7147
1.66
22.41
8.0
6.5
9.17
8.92
%
1.53
870
6675
1337
11381
1.83
22.34
5.3
4.6
14.87
14.90
pmol/l
0.22
1245
10409
925
7135
1.65
22.25
7.7
6.4
2.84
2.83
%
0.07
868
6660
1032
8200
1.66
21.97
6.3
6.7
11.59
11.59
umol/l
0.00
990
7825
509
3372
1.73
21.83
2.0
1.7
1.09
1.29
mg/l
1.21
387
2638
937
7279
1.64
21.68
7.8
6.5
27.17
27.00
%
0.18
886
6890
407
2546
1.79
21.24
4.0
3.2
3.27
2.61
e6/l
0.48
195
1259
1350
11591
1.82
21.07
9.3
8.4
77.68
80.23
u/l
1.20
1293
10970
433
2769
1.76
20.90
3.9
3.0
1.13
1.23
e6/l
0.23
220
1488
1501
13357
2.10
20.80
7.0
5.6
1.89
1.95
mu/l
1.21
1411
12289
1004
7987
1.63
20.68
7.3
6.5
0.19
0.19
e9/l
0.12
861
6910
1078
8731
1.65
20.64
10.3
9.7
4.31
4.14
e9/l
1.35
908
7582
978
7737
1.63
20.54
7.0
6.2
0.04
0.04
e9/l
0.28
816
6595
778
5848
1.61
19.97
5.2
4.1
167.36
118.96
e6/l
0.31
538
4123
988
7873
1.61
19.82
7.2
6.3
1.90
1.90
e9/l
0.00
854
6872
972
7723
1.61
19.67
6.9
6.2
0.62
0.59
e9/l
2.12
810
6580
695
5117
1.61
19.21
3.6
3.3
1334.35
1484.18
ng/l
0.50
612
4436
699
5162
1.60
19.03
4.3
3.5
74.28
79.74
e6/l
0.06
519
3968
667
4902
1.60
18.34
3.0
2.6
56.38
77.76
u/l
0.70
614
4535
1588
14599
2.44
17.86
27.8
20.8
139.55
139.59
mmol/l
0.27
1573
14322
1589
14616
2.45
17.79
28.0
21.0
3.96
3.98
mmol/l
3.09
1570
14313
302
1826
1.80
17.32
2.3
2.3
128.93
126.66
ug/g
0.04
240
1452
83
298
2.88
17.17
1.2
1.4
—
—
—
0
0
485
3346
1.63
17.07
1.4
1.3
1.16
1.50
u/ml
0.49
97
897
612
4468
1.58
16.98
4.1
3.3
0.39
0.46
e6/l
0.36
443
3313
89
336
2.74
16.76
1.3
1.4
71.34
57.75
e6/l
0.09
64
252
668
4988
1.56
16.72
3.6
3.2
43.77
33.92
u/l
0.32
632
4708
1489
13432
1.91
16.55
7.5
6.7
39.66
39.69
mmol/mol
0.03
1403
12484
258
1507
1.84
16.52
2.7
2.4
30.47
38.68
u/l
2.70
224
1268
89
340
2.71
16.39
1.3
1.4
2534.56
850.43
e6/l
0.34
66
270
825
6499
1.53
15.92
4.5
3.7
6.20
6.27
ph
1.03
441
3631
884
7079
1.52
15.71
2.9
2.5
77.74
78.64
nmol/l
0.44
811
6356
876
7041
1.51
15.03
3.5
3.1
104.78
124.78
ug/l
3.13
816
6528
401
2730
1.61
14.55
1.5
1.3
50.69
33.55
iu/ml
0.31
111
842
982
8112
1.50
14.54
5.2
4.2
0.00
2.76
estimate
1.08
174
1790
735
5726
1.50
14.49
3.0
3.6
2.37
2.36
mmol/l
1.66
654
5189
988
8177
1.50
14.46
5.3
4.3
0.13
0.19
estimate
0.13
168
1681
971
8014
1.50
14.36
5.3
4.2
0.00
0.00
estimate
0.50
172
1735
605
4555
1.51
13.91
4.3
4.3
—
—
—
0
0
201
1151
1.85
13.60
1.2
1.2
—
—
—
0
0
396
2729
1.59
13.53
2.7
3.2
0.83
0.82
mmol/l
1.01
371
2570
1603
15013
2.30
13.52
30.4
22.9
77.41
78.02
umol/l
0.28
1589
14836
1588
14833
2.16
13.22
15.2
12.7
25.13
25.13
u/l
0.00
1554
14398
296
1918
1.66
12.94
5.7
7.9
7.42
7.42
ph
0.99
162
1060
416
2931
1.56
12.82
1.6
1.5
2.27
2.45
g/l
1.22
221
1775
293
1904
1.65
12.64
5.7
7.9
1.05
1.02
mmol/l
0.04
231
1575
1315
11716
1.55
12.32
29.6
21.5
13.68
13.74
%
0.90
1305
11543
294
1924
1.64
12.32
5.7
7.9
12.24
12.09
kpa
0.17
286
1857
294
1924
1.64
12.32
5.7
7.9
4.99
5.10
kpa
1.20
285
1855
604
4644
1.47
12.11
6.8
6.3
—
—
—
0
0
48
158
3.10
11.63
1.1
1.4
—
—
—
0
0
365
2553
1.55
11.46
1.4
1.3
20.63
12.58
u/ml
0.26
125
935
366
2570
1.54
11.27
2.5
2.6
2.32
2.30
g/l
0.43
343
2372
299
2009
1.59
11.16
1.4
1.3
470.94
508.47
titre
0.12
53
472
742
5994
1.42
11.14
2.3
2.2
—
—
—
0
0
261
1699
1.63
11.10
6.0
8.3
95.40
95.39
%
0.01
255
1648
386
2752
1.52
11.06
2.6
2.6
13.07
12.48
umol/l
0.85
361
2561
562
4323
1.45
10.99
2.6
2.3
2.58
2.91
mg/l
3.59
491
3703
233
1483
1.66
10.81
2.0
2.1
377.62
383.58
nmol/l
0.16
219
1372
863
7207
1.40
10.48
2.9
2.8
—
—
estimate
—
0
0
267
1793
1.58
9.92
2.7
2.7
8.45
8.20
umol/l
0.06
237
1579
144
822
1.82
9.81
2.4
2.4
—
—
—
0
0
475
3603
1.44
9.80
2.9
2.8
5.75
6.04
e6/l
0.15
430
3287
1285
11576
1.46
9.72
31.6
22.7
331.74
331.38
g/l
0.77
1280
11502
129
715
1.87
9.65
1.8
2.6
3.72
3.71
g/l
0.02
116
660
218
1404
1.63
9.62
7.4
8.7
—
—
—
0
0
129
716
1.87
9.61
1.8
2.6
4.07
4.21
g/l
1.60
116
660
333
2366
1.51
9.55
2.5
2.6
22.87
22.06
%
0.45
311
2205
511
3946
1.42
9.51
2.5
2.8
336.07
345.74
umol/l
1.23
428
3445
206
1314
1.65
9.44
3.3
3.1
209.49
227.64
ng/l
0.14
190
1210
1607
15287
2.03
9.37
35.7
26.5
248.38
250.46
e9/l
0.65
1586
14979
1607
15290
2.03
9.32
35.5
26.4
91.24
91.38
fl
0.67
1597
15111
1607
15292
2.02
9.28
35.6
26.5
4.43
4.42
e12/l
0.56
1580
14934
1607
15292
2.02
9.28
36.2
27.0
39.87
39.77
%
0.33
1595
15105
1607
15292
2.02
9.28
35.5
26.4
30.33
30.34
pg
0.02
1597
15112
1513
14148
1.66
9.27
6.7
6.0
2.60
2.66
mmol/l
2.17
1422
13037
1607
15293
2.02
9.26
35.7
26.5
6.95
6.78
e9/l
1.62
1581
14934
115
623
1.91
9.23
1.9
2.6
9.71
10.47
g/l
1.19
102
561
1607
15296
2.02
9.21
35.8
26.7
133.16
133.05
g/l
0.10
1597
15120
1478
13749
1.60
9.17
6.2
5.4
6.02
5.98
mmol/l
0.55
1379
12522
250
1696
1.56
8.84
3.8
3.5
7.38
7.38
ph
0.16
129
991
417
3142
1.43
8.78
3.2
3.0
532.61
525.61
mosm/kgh2o
0.28
367
2759
1480
13813
1.57
8.58
5.7
5.1
1.43
1.48
mmol/l
5.28
1384
12691
1487
13901
1.58
8.47
5.8
5.2
4.51
4.60
mmol/l
2.74
1402
12863
240
1641
1.54
8.16
3.8
3.5
2.20
1.86
mmol/l
0.86
222
1416
307
2222
1.47
7.92
5.2
5.6
1.04
1.04
mmol/l
0.00
283
2047
40
149
2.73
7.86
1.2
1.6
—
—
—
0
0
1422
13228
1.47
7.65
4.7
4.4
1.34
1.28
mmol/l
2.61
1320
12025
788
6696
1.33
7.60
12.6
11.9
0.00
0.00
e9/l
0.35
615
5457
148
917
1.67
7.58
3.0
3.6
4.34
4.46
pmol/l
0.85
130
814
439
3415
1.39
7.54
3.0
3.0
2.46
2.46
mmol/l
0.08
382
3073
213
1447
1.54
7.45
2.1
3.0
65.89
66.48
g/l
0.67
184
1333
44
178
2.51
7.36
1.3
1.3
0.19
0.29
nmol/l
0.45
36
137
458
3600
1.37
7.35
5.3
4.4
1.02
1.44
kg/l
0.50
324
2403
272
1951
1.47
7.32
2.7
2.7
1.92
1.80
%
0.84
253
1738
715
6022
1.32
7.21
2.0
1.9
1.32
1.34
mmol/l
0.30
613
5024
199
1341
1.55
7.21
3.7
3.7
85.48
91.10
ng/l
0.40
175
1153
153
970
1.63
7.17
3.1
3.6
24.73
24.17
mmol/l
1.51
153
957
81
430
1.93
6.97
1.1
1.1
—
—
—
0
0
15
20
7.56
6.90
1.0
1.0
—
—
—
0
0
373
2868
1.39
6.78
1.8
1.8
1033.38
1190.53
nmol/l
2.85
284
2148
217
1518
1.49
6.59
2.6
2.7
72.50
69.57
e9/l
0.52
159
1114
25
79
3.20
6.58
1.1
1.2
0.61
0.50
ratio
0.65
13
47
150
968
1.60
6.55
1.3
1.3
129.65
219.86
u/ml
0.80
140
885
46
202
2.31
6.48
1.5
1.4
25.46
80.40
mu/l
1.25
41
182
251
1830
1.44
6.16
1.9
1.7
—
—
—
0
0
179
1235
1.50
5.82
3.5
3.0
6.00
6.07
ph
0.63
134
859
151
1006
1.55
5.77
1.3
1.3
—
—
—
0
0
604
5094
1.29
5.65
2.6
2.5
—
—
—
0
0
283
2139
1.39
5.63
1.3
1.2
—
—
—
0
0
473
3871
1.31
5.54
2.5
2.4
—
—
—
0
0
77
437
1.80
5.44
2.4
3.5
2.71
2.29
index
0.22
38
223
96
581
1.69
5.42
2.1
2.7
—
—
—
0
0
95
574
1.69
5.40
1.9
1.9
20.30
21.28
s
1.59
84
516
172
1198
1.49
5.34
3.0
3.0
10.10
10.79
g/l
1.48
160
1102
26
96
2.74
5.28
1.2
1.1
13.04
7.94
iu/ml
—
9
27
50
251
2.02
5.12
2.3
1.8
—
—
—
0
0
79
461
1.75
5.10
1.6
1.6
1.19
1.19
g/l
0.05
72
436
94
584
1.65
4.84
1.4
1.4
28.10
28.84
iu/l
0.08
80
506
67
382
1.79
4.70
1.1
1.1
—
—
—
0
0
181
1309
1.43
4.64
3.0
2.5
0.20
0.55
e6/l
3.17
170
1255
37
174
2.15
4.52
1.2
1.3
—
—
nmol/l
—
0
0
11
19
5.82
4.44
1.1
1.0
—
—
—
0
0
75
450
1.70
4.43
1.6
1.6
0.23
0.24
g/l
0.21
70
426
18
60
3.02
4.40
2.8
3.3
102.70
96.98
umol/l
—
10
42
25
101
2.50
4.30
1.0
1.1
1.38
5.29
nmol/l
—
5
17
15
38
3.97
4.30
1.2
1.7
535.40
811.79
nmol/24h
0.12
15
38
66
386
1.74
4.28
1.5
2.2
134.21
127.52
g/l
1.29
52
305
251
1948
1.34
4.19
1.6
1.6
—
—
—
0
0
143
1010
1.45
4.17
1.3
1.4
—
—
—
0
0
408
3385
1.27
4.14
1.8
1.8
67155862.12
19307544.70
pmol/l
0.75
341
2771
226
1732
1.35
4.10
1.3
1.3
—
—
—
0
0
54
303
1.81
4.04
1.2
1.1
—
—
—
0
0
45
238
1.92
4.04
1.1
1.7
0.85
0.79
g/l
0.13
35
192
57
329
1.76
3.89
1.4
1.2
36.58
53.25
u/ml
—
6
32
31
145
2.16
3.87
1.2
1.1
—
—
—
0
0
286
2287
1.30
3.86
2.0
2.1
—
—
—
0
0
151
1094
1.42
3.85
8.2
9.5
94.05
93.83
%
0.14
151
1087
105
709
1.51
3.84
1.2
1.2
—
—
—
0
0
613
5363
1.22
3.81
3.3
3.4
7.14
7.14
mmol/l
0.00
512
4525
62
372
1.69
3.71
1.5
1.8
—
—
—
0
0
69
427
1.64
3.68
1.3
1.1
—
—
—
0
0
62
375
1.68
3.61
1.5
1.7
—
—
—
0
0
120
845
1.45
3.59
4.4
3.7
1.02
1.02
ratio
0.55
113
772
181
1371
1.36
3.56
2.5
2.4
6.85
7.40
ug/l
0.11
149
1215
36
185
1.97
3.54
1.1
1.2
—
—
—
0
0
61
371
1.67
3.49
1.5
1.8
—
—
—
0
0
112
783
1.46
3.48
1.6
1.9
1.55
1.56
g/l
0.02
95
691
256
2046
1.30
3.46
1.4
1.3
—
—
—
0
0
58
351
1.68
3.39
1.5
1.8
—
—
—
0
0
12
32
3.77
3.39
1.4
1.5
—
—
—
0
0
194
1497
1.33
3.38
1.6
1.6
—
—
—
0
0
82
541
1.54
3.37
1.6
1.6
7.37
13.15
u/ml
1.50
13
104
240
1909
1.30
3.37
3.7
3.3
4.26
4.85
e9/l
0.89
203
1652
33
168
1.98
3.35
1.8
2.2
—
—
—
0
0
33
169
1.97
3.30
1.1
1.0
0.61
3.22
u/ml
2.36
18
79
134
979
1.40
3.29
1.2
1.2
104.24
133.06
u/ml
0.27
43
364
493
4276
1.22
3.24
4.9
3.7
1.77
0.23
estimate
0.42
145
1372
233
1856
1.30
3.24
1.6
1.4
—
—
—
0
0
45
258
1.76
3.20
1.8
2.5
—
—
—
0
0
21
91
2.32
3.17
1.5
1.2
—
—
—
0
0
197
1539
1.32
3.16
2.3
2.2
0.10
0.02
estimate
0.39
40
310
37
201
1.86
3.13
1.3
1.2
—
—
—
0
0
42
238
1.78
3.11
1.1
1.1
—
—
—
0
0
138
1026
1.38
3.07
3.7
3.9
7.42
7.42
ph
0.12
124
859
141
1052
1.37
3.07
3.7
3.9
5.20
5.18
kpa
0.10
131
1015
49
293
1.69
3.02
1.6
1.8
—
—
—
0
0
59
371
1.61
3.01
1.6
1.7
—
—
—
0
0
64
412
1.58
2.96
1.4
1.2
6.82
2.87
u/ml
—
5
37
105
750
1.43
2.95
2.4
2.0
—
—
—
0
0
64
413
1.57
2.94
1.5
1.2
3.37
10.39
u/ml
—
6
63
89
617
1.47
2.93
1.6
1.8
10.12
8.01
iu/ml
0.21
14
138
34
184
1.87
2.93
1.3
1.2
—
88.61
—
0
9
106
761
1.42
2.90
1.3
1.2
—
—
—
0
0
9
22
4.11
2.88
2.8
2.1
19.14
17.48
umol/l
—
9
22
37
207
1.81
2.88
1.1
1.1
0.64
1.37
u/ml
0.59
16
84
31
164
1.91
2.86
2.2
3.6
14.76
12.13
index
0.47
17
93
25
123
2.05
2.82
1.6
1.4
1676.04
1792.59
ml
0.41
25
118
28
144
1.96
2.80
1.1
1.0
0.04
0.38
u/ml
0.98
12
44
178
1397
1.31
2.78
1.5
1.5
—
—
—
0
0
30
159
1.90
2.76
1.1
1.1
3.69
4.56
u/ml
0.10
14
65
672
6072
1.18
2.71
5.6
4.2
3.58
0.13
estimate
0.48
142
1437
455
3979
1.20
2.68
5.9
5.8
2.42
2.85
ug/l
0.44
418
3585
37
212
1.76
2.68
1.1
1.0
4.65
4.28
u/ml
0.07
18
104
57
367
1.57
2.67
2.5
2.0
3829.37
6266.50
u/l
0.37
18
151
82
572
1.46
2.64
1.3
1.2
0.31
0.97
u/ml
—
9
35
269
2239
1.24
2.60
1.9
1.8
—
—
—
0
0
33
185
1.80
2.58
1.2
1.4
273.11
276.64
mosm/kgh2o
0.33
19
139
5
7
7.16
2.55
1.4
1.0
—
—
—
0
0
56
364
1.56
2.53
1.1
1.2
—
—
—
0
0
27
143
1.90
2.51
2.1
2.2
—
—
—
0
0
36
210
1.73
2.47
1.2
1.2
5.57
4.21
u/ml
0.18
14
90
584
5261
1.17
2.38
3.9
4.2
8.09
8.96
mg/mmol
0.15
354
3258
40
244
1.65
2.35
1.2
1.1
18.54
20.76
au/ml
—
10
56
35
206
1.71
2.35
4.9
5.5
368.59
357.98
umol/l
0.16
29
183
61
414
1.49
2.29
1.2
1.2
—
11.43
—
0
7
41
254
1.63
2.28
1.2
1.1
1.42
1.94
u/ml
0.18
21
138
78
556
1.42
2.28
1.5
1.6
0.27
0.32
mg/l
0.29
32
253
569
5131
1.16
2.27
3.3
3.5
37.78
46.16
mg/l
0.49
364
3269
6
13
4.63
2.27
2.2
1.7
—
—
—
0
0
33
193
1.72
2.27
1.1
1.0
0.48
1.77
u/ml
1.78
18
99
59
399
1.50
2.26
1.2
1.2
—
—
—
0
0
7
18
3.90
2.25
1.3
1.1
0.03
0.07
u/ml
—
7
18
60
409
1.48
2.22
2.0
2.0
3.89
17.82
iu/l
0.50
24
167
32
187
1.72
2.21
1.5
1.3
—
—
—
0
0
51
336
1.53
2.21
4.6
4.0
21.52
27.59
mg/l
0.78
39
230
7
19
3.69
2.15
2.1
2.8
2.00
1.95
%
—
7
19
80
581
1.40
2.13
1.1
1.1
—
—
—
0
0
180
1467
1.25
2.12
6.6
7.2
9.93
10.31
mmol/l
0.26
167
1409
26
146
1.79
2.07
1.1
1.4
—
—
—
0
0
52
351
1.50
2.04
1.5
1.3
65.86
58.53
mmol/l
0.64
42
286
19
97
1.97
2.00
1.5
1.2
—
—
—
0
0
13
57
2.29
1.98
1.2
1.1
173.80
85.06
ng/l
—
5
17
124
979
1.29
1.92
2.5
2.3
12.00
12.91
nmol/l
0.57
109
879
16
78
2.06
1.91
2.3
3.2
504.94
1007.29
u/ml
1.94
16
78
7
22
3.19
1.88
1.1
1.4
61.86
61.64
ug/l
—
7
22
80
595
1.36
1.87
1.9
2.2
384.92
440.32
ug/l
0.17
74
564
67
484
1.40
1.87
1.7
1.4
267.69
278.13
ug/g
0.15
39
287
43
285
1.52
1.85
2.4
2.0
4.92
4.80
mmol/24h
0.08
38
246
26
152
1.72
1.83
2.9
2.4
—
—
—
0
0
81
607
1.35
1.82
2.9
3.6
51.21
53.30
mg/l
0.03
73
526
13
60
2.18
1.78
1.2
1.2
202.36
210.39
iu/ml
0.06
13
60
28
169
1.67
1.77
1.6
1.4
23.85
23.41
ng/l
0.03
28
169
6
18
3.34
1.74
1.0
1.2
0.02
0.02
u/ml
—
6
18
25
147
1.71
1.74
1.1
1.4
2.94
2.86
g/l
0.07
18
110
25
147
1.71
1.74
1.1
1.4
0.32
0.42
g/l
0.98
18
110
25
147
1.71
1.74
1.1
1.4
5.86
7.04
g/l
1.12
18
112
9
36
2.51
1.74
1.6
2.3
—
—
—
0
0
58
417
1.40
1.69
1.2
1.2
140.00
92.82
titre
—
8
39
8
31
2.59
1.66
1.0
1.1
—
—
—
0
0
93
723
1.30
1.65
4.2
4.1
—
—
—
0
0
461
4180
1.14
1.64
1.4
1.4
—
—
—
0
0
39
262
1.50
1.61
1.2
1.2
224.08
257.07
u/ml
0.36
20
150
23
136
1.70
1.59
1.9
2.1
26.37
5.87
umol/l
0.67
18
99
37
247
1.51
1.58
1.3
1.4
167.92
159.57
au/ml
0.16
13
69
203
1733
1.19
1.57
2.7
4.3
52.55
18.64
ug/l
0.35
155
1444
130
1061
1.24
1.57
1.6
1.6
—
—
—
0
0
79
605
1.32
1.57
3.0
3.6
35.36
144.52
mg/l
0.67
72
523
41
281
1.47
1.55
1.4
1.3
—
—
—
0
0
29
185
1.58
1.52
16.8
6.7
7.87
7.40
mmol/l
0.29
23
156
118
957
1.25
1.51
2.2
1.9
1.06
1.48
g/l
3.22
109
884
12
58
2.08
1.49
1.5
1.3
11.92
10.14
mm/h
0.23
12
58
185
1580
1.19
1.44
2.2
2.3
0.22
0.20
g/l
1.68
173
1469
55
405
1.37
1.43
1.7
1.6
10172.70
14309.08
e6/l
0.50
37
284
96
767
1.27
1.41
4.6
3.0
25.84
25.39
mmol/l
0.78
96
742
71
547
1.31
1.38
3.1
3.5
1.14
3.89
ratio
2.06
39
323
73
565
1.31
1.38
3.2
3.5
346.17
387.21
mg/l
0.11
29
234
20
120
1.67
1.34
2.1
3.1
18.27
24.53
mg/l
0.19
13
84
6
24
2.51
1.30
1.3
1.1
—
—
—
0
0
31
210
1.49
1.28
1.3
1.2
—
—
—
0
0
71
555
1.29
1.26
1.4
1.2
—
—
—
0
0
20
123
1.63
1.24
1.3
1.1
—
—
—
0
0
23
147
1.57
1.23
1.1
1.2
—
—
—
0
0
94
764
1.24
1.23
2.1
2.3
0.00
1.09
estimate
0.50
30
230
11
56
1.97
1.22
1.4
1.2
42.21
126.95
nmol/l
—
6
41
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
16
93
1.73
1.21
1.1
1.1
—
—
—
0
0
6
26
2.31
1.18
1.0
1.4
—
—
—
0
0
30
206
1.46
1.18
1.1
1.1
—
—
—
0
0
14
79
1.78
1.17
1.0
1.2
130.86
139.90
nmol/l
0.45
14
79
30
207
1.46
1.15
1.1
1.1
—
—
—
0
0
8
39
2.06
1.15
1.1
1.3
27.38
28.36
s
—
8
39
5
20
2.50
1.15
1.0
1.2
—
—
—
0
0
26
175
1.49
1.13
1.8
1.3
—
—
—
0
0
208
1835
1.15
1.12
5.2
5.0
32.82
32.89
%
0.03
141
1192
10
51
1.97
1.11
1.0
1.1
—
—
—
0
0
10
51
1.97
1.11
3.3
1.5
33.50
32.16
%
—
10
51
85
694
1.24
1.09
1.6
2.0
0.51
1.80
ug/l
2.09
73
618
11
193
0.57
1.07
1.6
1.4
—
—
—
0
0
24
161
1.50
1.07
5.7
4.3
—
—
—
0
0
34
245
1.40
1.06
1.1
1.0
—
—
—
0
0
43
324
1.34
1.03
1.3
1.3
14.09
10.14
u/l
0.82
32
260
19
122
1.56
1.02
1.4
1.1
367.33
378.21
nmol/l
0.06
12
105
48
368
1.31
1.02
5.5
3.1
7.17
7.72
mmol/l
0.86
48
358
69
555
1.25
1.02
2.9
2.9
24.65
24.86
mmol/l
0.18
69
548
262
2367
1.13
1.00
3.5
3.3
0.82
0.77
ug/l
0.42
179
1591
12
198
0.60
0.95
1.4
1.4
131028.86
133055.33
e6/l
—
7
102
9
51
1.77
0.94
2.4
2.3
138.22
139.30
nmol/l
—
9
46
22
150
1.47
0.93
1.1
1.1
—
—
—
0
0
13
78
1.67
0.91
3.2
2.9
—
—
—
0
0
56
448
1.26
0.89
3.3
3.9
3.76
3.90
mmol/l
1.67
56
442
40
306
1.31
0.89
3.6
4.6
2.08
2.68
mmol/l
0.74
29
211
17
111
1.54
0.87
1.1
1.2
—
—
—
0
0
37
281
1.32
0.87
1.9
1.6
—
—
—
0
0
50
622
0.80
0.83
1.7
1.8
—
—
—
0
0
17
114
1.50
0.79
1.3
1.1
—
—
—
0
0
16
108
1.49
0.73
1.1
1.0
—
—
—
0
0
9
55
1.64
0.73
3.3
4.0
—
—
—
0
0
7
39
1.80
0.72
1.3
1.2
—
—
—
0
0
7
39
1.80
0.72
1.1
1.2
—
—
—
0
0
169
1522
1.12
0.72
4.7
4.5
7.38
7.36
ph
1.85
116
1101
9
56
1.61
0.72
1.2
1.3
162.11
164.94
mmol/24h
—
9
56
28
211
1.33
0.72
1.2
1.4
—
—
—
0
0
28
211
1.33
0.72
1.2
1.4
—
—
—
0
0
28
211
1.33
0.72
1.2
1.4
—
—
—
0
0
28
211
1.33
0.72
1.2
1.4
—
—
—
0
0
7
40
1.75
0.71
1.0
1.0
—
—
—
0
0
7
40
1.75
0.71
1.0
1.3
—
—
—
0
0
7
42
1.67
0.68
1.0
1.1
—
—
—
0
0
7
42
1.67
0.68
1.0
1.1
—
—
—
0
0
7
42
1.67
0.68
1.0
1.1
—
—
—
0
0
26
340
0.76
0.67
1.1
1.5
145.31
247.35
pmol/l
0.70
26
332
18
249
0.72
0.67
1.9
1.5
28.21
32.04
g/l
0.92
18
225
24
181
1.33
0.63
1.2
1.1
—
—
—
0
0
41
335
1.23
0.60
2.9
4.0
—
—
—
0
0
11
72
1.53
0.59
1.2
1.2
—
—
—
0
0
86
977
0.87
0.58
1.4
1.4
—
—
—
0
0
25
193
1.30
0.57
1.2
1.1
0.71
2.34
eliau/ml
—
7
82
127
1144
1.12
0.57
1.5
1.4
—
—
—
0
0
493
5155
0.94
0.57
3.5
3.3
—
—
—
0
0
156
1422
1.11
0.57
5.7
4.3
0.89
0.91
%
0.04
58
423
9
60
1.50
0.54
3.3
3.7
—
—
—
0
0
26
204
1.28
0.54
1.8
2.3
0.99
1.37
g/24h
0.31
14
119
11
74
1.49
0.53
2.7
1.5
—
—
—
0
0
10
66
1.52
0.52
1.1
1.9
41.15
40.03
g/l
—
10
66
6
40
1.50
0.51
1.2
1.2
35.72
27.72
nmol/l
—
6
32
19
144
1.32
0.50
1.1
1.1
110.47
107.31
pmol/l
0.11
19
144
6
41
1.47
0.50
1.5
1.5
7.20
6.51
mmol/l
—
6
41
147
1349
1.10
0.49
4.8
4.1
0.64
0.70
%
0.09
53
394
17
223
0.76
0.48
1.5
1.4
1435.80
1674.20
e6/l
—
10
149
7
47
1.49
0.47
1.0
1.6
—
—
—
0
0
81
908
0.89
0.47
2.0
1.8
3.34
3.46
mmol/l
0.50
54
649
7
49
1.43
0.46
1.0
1.4
—
—
—
0
0
148
1365
1.09
0.45
5.5
4.3
0.13
0.12
%
0.08
50
366
9
128
0.70
0.43
1.6
1.3
—
—
—
0
0
5
31
1.61
0.43
1.2
1.1
15.92
43.91
iu/ml
—
5
31
5
31
1.61
0.43
3.6
5.8
9.90
8.46
mmol/l
—
5
31
43
369
1.17
0.42
1.4
1.3
200.84
259.97
miu/ml
0.53
22
165
8
58
1.38
0.41
1.1
1.1
1099.75
1649.47
miu/ml
—
8
58
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
18.27
—
0
16
0
17
0.00
0.40
0.0
1.5
—
8.26
—
0
7
115
1251
0.91
0.40
4.9
4.2
—
—
—
0
0
0
18
0.00
0.40
0.0
3.6
—
19.05
—
0
6
40
344
1.17
0.39
2.1
1.8
45.28
41.82
nmol/l
0.42
40
326
48
420
1.15
0.38
6.1
4.8
—
—
—
0
0
146
1363
1.08
0.36
5.6
4.6
0.23
0.11
%
0.57
47
335
6
42
1.43
0.35
1.0
1.2
34.45
38.36
g/l
—
6
22
24
199
1.21
0.35
1.6
1.9
—
—
—
0
0
16
127
1.26
0.33
1.8
1.5
23.47
30.73
%
—
10
76
15
118
1.27
0.33
1.7
1.4
14.20
13.88
u/l
0.07
15
112
15
186
0.80
0.31
1.3
1.5
—
—
—
0
0
70
639
1.10
0.30
1.9
3.6
20.58
2477.75
u/ml
0.95
55
556
34
388
0.87
0.29
1.6
1.6
—
—
—
0
0
38
430
0.88
0.29
1.4
1.6
972.24
999.25
mu/l
0.08
29
355
18
148
1.22
0.29
1.1
1.1
—
—
—
0
0
21
176
1.20
0.29
1.4
1.3
29.75
26.12
u/l
0.18
16
146
13
103
1.26
0.28
2.0
1.4
1.38
1.00
promille
0.35
13
80
47
422
1.12
0.28
1.3
1.3
—
—
—
0
0
8
63
1.27
0.27
1.0
1.2
—
14.56
—
0
9
471
4585
1.04
0.27
5.8
4.3
0.00
0.01
estimate
1.54
161
1605
15
183
0.82
0.27
1.7
1.6
—
—
—
0
0
18
150
1.20
0.26
1.8
1.3
52127.82
160471.83
e6/l
0.75
11
98
20
169
1.19
0.26
3.3
2.6
—
—
—
0
0
9
73
1.23
0.25
1.3
2.9
1941.11
1854.45
ml
—
9
64
26
226
1.15
0.25
2.5
2.7
—
—
—
0
0
17
202
0.84
0.24
1.4
1.5
—
—
—
0
0
12
96
1.25
0.24
1.6
1.4
70.25
83.74
umol/l
0.98
12
96
19
161
1.18
0.24
1.4
1.2
—
—
—
0
0
5
39
1.28
0.23
1.6
2.7
—
—
—
0
0
17
200
0.85
0.22
1.3
1.5
1.18
1.29
mm
0.47
11
145
42
461
0.91
0.21
10.5
11.8
—
—
—
0
0
25
283
0.88
0.21
2.9
3.5
4.11
4.25
e9/l
0.14
25
283
117
1231
0.95
0.21
2.1
2.0
3.51
3.41
ratio
0.45
87
969
34
306
1.11
0.21
1.5
1.9
0.86
0.88
nmol/l
0.04
27
255
0
14
0.00
0.20
0.0
1.0
—
17.29
—
0
7
0
14
0.00
0.20
0.0
1.4
—
6.21
—
0
9
13
108
1.21
0.20
1.7
2.4
8.08
8.75
mmol/l
0.24
13
108
11
133
0.83
0.19
1.5
1.2
6.27
11.83
u/l
2.92
11
121
138
1322
1.05
0.19
4.0
3.8
1.23
1.23
mmol/l
0.10
122
1133
24
269
0.89
0.18
1.2
1.2
—
—
—
0
0
144
1384
1.04
0.17
1.4
1.4
—
—
—
0
0
37
403
0.92
0.17
1.1
1.1
1.48
1.56
g/l
1.10
37
403
12
104
1.15
0.12
1.2
2.4
6.16
6.93
mmol/l
—
7
66
12
137
0.88
0.12
7.3
5.4
47.00
45.42
u/ml
—
5
44
11
95
1.16
0.11
1.0
1.7
—
—
—
0
0
21
192
1.09
0.10
2.2
1.9
20.86
20.89
ug/l
0.00
21
187
25
231
1.08
0.10
3.3
2.7
—
—
—
0
0
5
45
1.11
0.09
1.2
1.1
—
—
—
0
0
25
232
1.08
0.09
3.1
2.3
1.11
0.89
%
0.36
14
157
19
207
0.92
0.09
1.4
1.6
—
—
—
0
0
337
3323
1.02
0.09
4.9
4.7
—
—
—
0
0
13
116
1.12
0.09
1.5
1.1
—
100.67
—
0
6
17
155
1.10
0.09
1.4
1.3
—
—
—
0
0
6
54
1.11
0.09
1.7
2.5
0.66
0.61
mmol/l
—
6
54
40
420
0.95
0.08
1.1
1.2
0.84
0.91
g/l
1.03
40
420
7
68
1.03
0.07
1.1
1.5
—
2.44
—
0
9
8
92
0.87
0.06
1.1
1.1
—
—
—
0
0
8
95
0.84
0.06
1.1
2.8
16.46
16.37
%
—
8
95
9
101
0.89
0.06
1.3
1.6
83.78
107.80
ng/l
—
9
101
34
355
0.96
0.06
1.8
2.4
43.31
80.80
ug/min
0.97
20
215
19
178
1.07
0.05
1.7
2.1
—
—
—
0
0
14
148
0.95
0.02
1.6
2.4
1.29
2.05
u/field
—
7
85
18
174
1.03
0.00
1.8
2.3
—
—
—
0
0
18
185
0.97
0.00
1.7
1.7
—
—
—
0
0
12
119
1.01
0.00
1.0
1.0
772.43
687.79
ng/l
—
7
75
19
189
1.01
0.00
1.1
1.2
—
—
—
0
0
34
345
0.99
0.00
2.6
3.4
56.47
58.37
%
0.31
34
345
18
178
1.01
0.00
1.9
1.6
69.11
60.27
%
0.44
12
113
20
198
1.01
0.00
1.5
1.3
—
—
—
0
0
26
257
1.01
0.00
1.3
1.5
61.59
62.19
ug/l
0.02
20
218
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
247.57
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
98.80
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
8
89
0.90
-0.00
1.6
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
54
0.93
-0.00
2.2
2.0
—
—
—
0
0
6
60
1.00
-0.00
1.7
1.4
139.40
163.12
pmol/l
—
6
60
0
5
0.00
-0.00
0.0
1.0
—
3.74
—
0
5
5
58
0.86
-0.00
51.2
32.3
124.80
129.91
ug/l
—
5
44
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
57
0.88
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_VESTIFUNCNAS and mortality.

Females

Parameter HR [95% CI] p-value
H8_VESTIFUNCNAS 1.017 [0.9, 1.14] 0.778
Birth year 0.994 [0.99, 1.0] 0.148

During the follow-up period (1.1.1998 — 31.12.2019), 998 out of 4177 females with H8_VESTIFUNCNAS died.

Males

Parameter HR [95% CI] p-value
H8_VESTIFUNCNAS 1.072 [0.92, 1.25] 0.379
Birth year 0.988 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 515 out of 2384 males with H8_VESTIFUNCNAS died.

Mortality risk

Mortality risk for people of age

years, who have H8_VESTIFUNCNAS.

N-year risk Females Males
1 0.075% 0.234%
5 0.553% 1.328%
10 1.479% 3.317%
15 2.903% 6.326%
20 4.988% 10.675%

Relationships between endpoints

Index endpoint: H8_VESTIFUNCNAS – Other/unspecified disorders of vestibular function

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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