No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1452 |
4. Check minimum number of eventsNone |
1452 |
5. Include endpointsNone |
1452 |
6. Filter based on genotype QC (FinnGen only) |
1261 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H49
- Name in latin
- Paresis/paralysis nervi abducentis
Similar endpoints
↥List of similar endpoints to
Sixth [abducent] nerve palsy
based on the number of shared cases.
Similar with more cases:
- Paralytic strabismus
- Strabismus
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7973 | 4049 | 3894 |
| Only index persons | 7178 | 3707 | 3471 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.11 |
| Only index persons | 0.13 | 0.14 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 63.91 | 64.87 | 62.88 |
| Only index persons | 63.69 | 64.69 | 62.63 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1261 | 633 | 628 |
| Unadjusted period prevalence (%) | 0.26 | 0.22 | 0.29 |
| Median age at first event (years) | 63.32 | 61.84 | 64.81 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1319
- Matched controls
- 13190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
307.7
1319
*
H53.2
ICD-10 Finland
Diplopia
83.7
307.7
607
133
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.6
149.8
351
807
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.1
143.7
294
596
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
9.9
121.9
148
167
AA1AD
NOMESCO Finland
CT of head and brain
3.2
92.8
635
2969
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
872.1
84.5
82
*
XCK00
NOMESCO Finland
Perimetry
5.2
83.4
189
411
G35
ICD-10 Finland
Multiple sclerosis
14.2
79.8
74
55
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
79.0
75
*
109
Kela drug reimbursment
Multiple sclerosis
19.5
73.9
58
31
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
21.2
72.7
55
27
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.9
71.4
240
706
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
16.4
71.3
61
39
G51.0
ICD-10 Finland
Bell palsy
8.1
71.2
99
131
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
68.3
65
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
68.1
375
1503
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
21.6
66.6
50
24
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
648.2
63.4
62
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.7
50.4
72
98
A10AB05
ATC
insulin aspart; parenteral
3.5
49.2
185
580
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
19.5
48.5
38
20
A10AE04
ATC
insulin glargine; parenteral
3.1
46.5
218
782
A10AC01
ATC
insulin (human); parenteral
3.4
45.1
178
574
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
18.5
44.8
36
20
CE2W4
NOMESCO Finland
Eye movement mapping
121.8
44.0
47
*
TAB00
NOMESCO Finland
Lumbar puncture
4.5
44.0
113
269
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
10.8
40.4
44
42
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.3
38.6
66
109
A10AA02, ,
ATC
4.8
37.3
88
195
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.4
36.4
142
453
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
35.6
34
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.8
34.9
198
783
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.0
34.8
102
268
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.5
34.7
88
207
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
6.1
34.5
61
104
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.6
33.5
215
904
A10AB01
ATC
insulin (human); parenteral
4.6
33.1
81
185
H3603, E103,
ICD-10 Finland
13.2
32.4
31
24
A10AA01, ,
ATC
5.3
31.9
65
127
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
7.5
29.8
43
59
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.1
29.3
63
129
XCK10
NOMESCO Finland
Photography of fundus of eye
2.6
29.1
185
772
T89
ICPC
Diabetes insulin dependent
3.8
28.2
89
246
B01AC04
ATC
clopidogrel; oral
2.1
27.6
307
1634
CEC00
NOMESCO Finland
Recession of extraocular muscle
276.5
26.8
27
*
R51.80
ICD-10 Finland
Headache
2.3
26.1
238
1167
A10AB04
ATC
insulin lispro; parenteral
4.2
24.9
67
165
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
9.3
24.8
30
33
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
10.2
24.8
28
28
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
24.7
431
2676
H46
ICD-10 Finland
Optic neuritis
9.5
24.5
29
31
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.9
22.9
115
423
H04AA01
ATC
glucagon; nasal, parenteral
5.3
22.3
45
87
PA6AD
NOMESCO Finland
CT of neck arteries
3.4
22.3
82
251
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
21.9
21
*
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
21.7
119
459
H50.51
ICD-10 Finland
Esophoria
223.6
21.7
22
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
8.9
21.6
27
31
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
21.6
385
2390
CS494
NOMESCO Finland
Other visual field testing
4.0
21.2
61
158
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
8.6
21.1
27
32
E10
ICD-10 Finland
Type 1 diabetes mellitus
5.5
21.0
41
77
H36.01
ICD-10 Finland
Diabetic maculopathy
5.9
20.2
36
62
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
7.1
20.0
30
43
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
5.6
19.9
38
70
L03AX13
ATC
glatiramer acetate; parenteral
29.4
19.7
26
9
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
8.5
19.3
25
30
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
18.8
18
*
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
18.8
18
*
R42
ICD-10 Finland
Dizziness and giddiness
1.8
18.6
345
2153
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.7
18.5
43
94
SPAT1262
SPAT
Handing over of treatment supplies
1.9
18.5
264
1516
A10AE05
ATC
insulin detemir; parenteral
2.7
18.2
100
386
H02.2
ICD-10 Finland
Lagophthalmos
16.8
17.9
28
17
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.3
17.8
67
208
F05
ICPC
Visual disturbance other
3.3
17.6
67
210
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
17.4
684
5209
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
17.4
577
4210
C10AA05
ATC
atorvastatin; oral
1.7
17.4
608
4496
164
Kela drug reimbursment
Fingolimod
42.6
17.3
21
5
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.5
17.2
110
457
H3600, E103,
ICD-10 Finland
7.3
17.0
25
35
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
7.3
17.0
25
35
H3601, E113,
ICD-10 Finland
4.6
16.9
40
89
L03AB07
ATC
interferon beta-1a; parenteral
15.3
16.7
27
18
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
16.6
372
2438
H50.9
ICD-10 Finland
Strabismus, unspecified
91.2
16.6
18
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.4
16.6
24
33
H3600, E113,
ICD-10 Finland
5.8
16.4
30
53
353
Kela drug reimbursment
Cladribine and fingolimod
40.6
16.4
20
5
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.6
16.2
38
84
H50.2
ICD-10 Finland
Vertical strabismus
48.1
16.0
19
*
A10AD01
ATC
insulin (human); parenteral
4.3
15.8
41
98
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.0
15.8
72
251
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
15.7
128
594
H50.8
ICD-10 Finland
Other specified strabismus
+∞
15.7
15
*
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.8
15.5
35
75
H3601, E103,
ICD-10 Finland
12.5
15.4
27
22
N86
ICPC
Multiple sclerosis
15.0
15.4
25
17
L04AX07
ATC
dimethyl fumarate; oral
23.7
15.1
21
9
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.6
15.1
50
143
C08CA01
ATC
amlodipine; oral
1.6
14.9
555
4119
T90
ICPC
Diabetes non-insulin dependent
1.7
14.6
357
2383
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4.0
14.3
41
106
L04AA27
ATC
[U] fingolimod
43.0
14.1
17
*
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
4.3
13.9
36
86
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
75.9
13.6
15
*
A10BB01
ATC
glibenclamide; oral
2.8
13.5
69
256
S06.2
ICD-10 Finland
Diffuse brain injury
6.1
13.4
23
38
A10AE06
ATC
insulin degludec; parenteral
2.9
13.2
62
220
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
4.8
13.1
29
61
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.0
13.0
58
200
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.8
12.9
29
62
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.4
12.8
91
397
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.7
12.8
67
252
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
12.8
132
672
Z3231
NOMESCO Finland
Registered nurse
1.6
12.7
362
2500
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
12.5
12
*
3785A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Paralytic strabismus
+∞
12.5
12
*
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
12.5
12
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
9.4
12.5
25
27
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
6.3
12.5
21
34
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.9
12.4
27
56
N03AX16
ATC
[U] pregabalin
1.7
12.3
301
1998
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
37.9
12.2
15
*
CKC12
NOMESCO Finland
Photocoagulation of retina
2.7
12.2
66
253
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
12.1
280
1834
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
4.5
11.9
29
66
A10AD05
ATC
insulin aspart; parenteral
3.4
11.6
41
123
C10AA01
ATC
simvastatin; oral
1.5
11.5
575
4479
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
5.4
11.4
22
41
ZXA10
NOMESCO Finland
Bilateral
1.7
11.3
252
1631
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
9.0
11.3
23
26
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.6
11.2
37
106
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
20.2
11.1
16
8
H57.1
ICD-10 Finland
Ocular pain
2.7
11.1
58
218
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.7
11.0
59
225
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
4.9
11.0
24
50
N03AX12
ATC
[U] gabapentin; oral
1.7
11.0
211
1311
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.1
10.9
44
143
CKC15
NOMESCO Finland
Panretinal photocoagulation
5.2
10.8
22
43
H3603, E113,
ICD-10 Finland
5.3
10.6
21
40
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
5.1
10.5
22
44
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
10.1
10.5
20
20
A10BA02
ATC
metformin; oral
1.5
10.5
395
2886
A10BB12
ATC
glimepiride; oral
2.1
10.5
108
549
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.1
10.5
44
147
ZXD05
NOMESCO Finland
Urgent procedure
1.5
10.4
385
2802
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
10.4
350
2496
XA800
NOMESCO Finland
Neuropsychological investigation
2.5
10.3
62
251
XCW10
NOMESCO Finland
Assessment of vision
3.7
10.1
32
89
A28
ICPC
Limited function/disability NOS
1.6
10.1
269
1815
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
14.7
10.0
16
11
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
10.0
826
7028
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
40.4
10.0
12
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.2
9.9
80
370
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
26.2
9.8
13
5
H16.0
ICD-10 Finland
Corneal ulcer
2.3
9.8
71
313
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
3.8
9.8
29
77
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.8
9.8
29
77
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.5
9.8
59
239
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
9.6
9.8
19
20
H25.8
ICD-10 Finland
Other senile cataract
1.8
9.7
161
957
H52.2
ICD-10 Finland
Astigmatism
7.4
9.7
22
30
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.6
9.7
31
87
H50.52
ICD-10 Finland
Exophoria
13.5
9.7
16
12
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.0
9.7
42
143
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
9.6
239
1585
SPAT1229
SPAT
Assessment of need for aid
2.0
9.4
106
556
H02AB09
ATC
hydrocortisone; systemic
3.1
9.4
39
129
A02BC02
ATC
pantoprazole; systemic
1.5
9.4
873
7551
L03AB08
ATC
interferon beta-1b; parenteral
21.9
9.4
13
6
N29
ICPC
Neurological sympt/complt other
3.3
9.3
34
104
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.9
9.3
122
676
S18
ICPC
Laceration/cut
1.4
9.2
615
4999
H52.1
ICD-10 Finland
Myopia
3.9
9.2
26
67
ZX120
NOMESCO Finland
Intravenous
1.9
9.1
128
724
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
11.6
9.1
16
14
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
9.1
160
969
C09AA02
ATC
enalapril; systemic
1.6
9.0
260
1785
XCH00
NOMESCO Finland
Eye pressure measurement
2.2
9.0
74
345
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.9
283
1985
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.8
8.5
41
148
G70.0
ICD-10 Finland
Myasthenia gravis
10.1
8.5
16
16
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.6
8.5
247
1698
H47.1
ICD-10 Finland
Papilloedema, unspecified
7.4
8.5
19
26
XCW20
NOMESCO Finland
Eye Movement Research, HESS
90.6
8.4
9
*
C09AA05
ATC
ramipril; oral
1.5
8.4
342
2523
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
8.4
113
631
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
8.4
376
2827
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
8.4
208
1377
AAH50
NOMESCO Finland
Cranial nerve anastomosis
+∞
8.3
8
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.9
8.3
39
139
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.2
321
2345
ZXC95
NOMESCO Finland
Use of surgical navigator
3.9
8.2
23
59
G91.0
ICD-10 Finland
Communicating hydrocephalus
8.2
8.1
17
21
CBH25
NOMESCO Finland
Tarsorrhaphy
33.6
8.1
10
*
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
6.9
8.1
19
28
L04AA31
ATC
[U] teriflunomide
22.2
8.0
11
5
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.9
8.0
37
131
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
7.3
8.0
18
25
H02AB06
ATC
prednisolone; systemic
1.4
7.9
590
4842
N07AA02
ATC
pyridostigmine; systemic
7.8
7.9
17
22
N06AA09
ATC
amitriptyline; systemic
1.8
7.8
120
698
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
7.7
185
1213
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.0
7.6
32
107
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
7.6
208
1405
N06AX21
ATC
duloxetine; oral
1.7
7.6
143
880
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
8.1
7.6
16
20
205
Kela drug reimbursment
Chronic hypertension
1.4
7.6
357
2699
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
4.1
7.5
20
49
L28
ICPC
Limited function/disability (L)
1.5
7.5
254
1799
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
7.5
141
868
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
7.5
444
3497
TKC22
NOMESCO Finland
Catheterisation instruction
2.8
7.5
37
136
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
7.5
200
1346
XCW11
NOMESCO Finland
Assessment of strabismus
80.5
7.4
8
*
H50.31
ICD-10 Finland
Intermittent exotropia
80.5
7.4
8
*
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
3.4
7.4
26
78
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
7.7
7.4
16
21
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
13.4
7.4
12
9
G91.1
ICD-10 Finland
Obstructive hydrocephalus
8.4
7.3
15
18
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
7.3
70
347
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
7.3
431
3389
108
Kela drug reimbursment
Myasthenia gravis
10.9
7.3
13
12
H51.2
ICD-10 Finland
Internuclear ophthalmoplegia
+∞
7.3
7
*
H49.9
ICD-10 Finland
Paralytic strabismus, unspecified
+∞
7.3
7
*
H50.4
ICD-10 Finland
Other and unspecified heterotropia
+∞
7.3
7
*
G52.8
ICD-10 Finland
Disorders of other specified cranial nerves
+∞
7.3
7
*
S02.10
ICD-10 Finland
Fracture of base of skull, closed
9.4
7.3
14
15
WX140
NOMESCO Finland
Parabulbar anesthesy
2.0
7.2
72
363
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.7
7.2
22
60
H02.4
ICD-10 Finland
Ptosis of eyelid
2.5
7.1
44
181
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.1
7.1
63
303
A06AD11
ATC
lactulose; oral
1.6
7.1
199
1352
Z50.1
ICD-10 Finland
Other physical therapy
2.0
7.1
71
358
E66.00
ICD-10 Finland
Metabolic syndrome
2.0
7.1
73
372
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
6.1
7.1
18
30
G63.2
ICD-10 Finland
Diabetic polyneuropathy
8.8
7.1
14
16
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
8.8
7.1
14
16
H47.2
ICD-10 Finland
Optic atrophy
8.8
7.1
14
16
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.0
173
1141
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
4.2
7.0
18
43
AAF00
NOMESCO Finland
Ventriculostomy
5.9
6.9
18
31
H26.4
ICD-10 Finland
After-cataract
1.7
6.8
137
858
G44.2
ICD-10 Finland
Tension-type headache
1.6
6.8
153
988
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.8
419
3315
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
6.7
149
957
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
6.7
280
2065
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
22.6
6.7
9
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
6.5
6.6
16
25
A10AA03, ,
ATC
4.0
6.6
18
45
J01CA04
ATC
amoxicillin; systemic
1.4
6.6
995
9037
OAB50, ,
SPAT
1.7
6.6
110
656
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
4.2
6.6
17
41
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.8
6.5
93
529
J01MA12
ATC
levofloxacin; systemic
1.5
6.5
233
1666
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.5
6.5
188
1285
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
6.9
6.5
15
22
A10BH01
ATC
sitagliptin; oral
1.7
6.5
128
798
J01DB01
ATC
cefalexin; oral
1.4
6.5
1020
9312
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.5
415
3295
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
2.6
6.5
35
135
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
3.2
6.5
25
80
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.5
205
1431
AAA10
NOMESCO Finland
Biopsy through craniotomy
70.2
6.4
7
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
70.2
6.4
7
*
AN4
HP
Balloon angioplasty and drug eluding stent
2.2
6.4
51
236
ZXA05
NOMESCO Finland
Left side
1.4
6.4
300
2261
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.3
6.3
47
211
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
6.3
78
424
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
6.3
307
2327
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
9.3
6.3
12
13
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
6.3
6
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
6.3
6
*
H49.8
ICD-10 Finland
Other paralytic strabismus
+∞
6.3
6
*
D33.12
ICD-10 Finland
Cerebellum
+∞
6.3
6
*
H50.59
ICD-10 Finland
Heterophor UNS
+∞
6.3
6
*
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
+∞
6.3
6
*
N18
ICPC
Paralysis/weakness
2.6
6.2
34
132
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
6.2
73
391
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.2
1134
10589
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
6.1
107
647
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
3.8
6.1
18
48
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.1
6.1
25
83
WX872
NOMESCO Finland
Intensive care
1.9
6.1
71
379
N01
ICPC
Headache
1.7
6.1
122
765
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
6.1
163
1097
C10AX09
ATC
ezetimibe; oral
1.5
6.0
215
1535
WX882
NOMESCO Finland
High dependency care
2.4
6.0
41
177
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
6.0
189
1315
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.0
346
2695
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
82
68
12.79
82.90
1.1
1.1
3.19
3.86
nmol/l
0.11
17
15
124
275
4.87
52.81
1.5
1.7
396.94
610.75
e6/l
0.18
101
212
123
272
4.88
52.56
1.5
1.6
125.21
67.50
e6/l
0.26
95
202
60
62
10.09
52.18
1.2
1.0
1.36
1.13
u/l
0.59
30
30
652
3844
2.38
51.19
2.4
2.3
160.65
227.74
u/l
1.14
631
3659
393
1997
2.38
41.65
2.0
2.2
28.90
29.66
s
1.61
380
1944
66
102
6.76
41.15
1.1
1.1
—
—
—
0
0
57
77
7.69
40.10
1.2
1.1
49.25
40.91
mg/l
0.42
44
63
54
69
8.12
39.81
1.1
1.0
—
—
—
0
0
55
72
7.93
39.73
1.1
1.1
330.77
264.95
mg/l
0.37
47
61
67
121
5.78
35.77
1.8
1.5
—
—
—
0
0
945
7103
2.17
34.41
6.5
5.4
7.28
6.75
mmol/l
8.24
910
6767
179
682
2.88
33.78
1.3
1.3
62.33
59.82
au/ml
—
6
53
190
750
2.79
33.54
2.4
2.5
15.68
21.74
au/ml
0.56
11
65
46
60
7.91
33.30
1.4
1.2
0.69
0.50
ratio
1.57
23
35
769
5859
1.75
21.19
12.3
17.2
1.19
1.29
inr
7.53
645
4908
650
4731
1.74
21.03
4.7
4.2
36.17
75.25
ng/l
1.23
504
3550
123
494
2.64
20.70
1.9
2.0
35.91
40.09
u/l
1.33
112
439
30
46
6.65
18.80
1.0
1.0
423.70
94.78
ng/l
—
10
9
31
51
6.20
18.17
1.9
2.0
—
—
—
0
0
790
6249
1.66
17.26
9.5
7.6
1.21
1.21
mmol/l
0.04
681
5403
726
5624
1.65
17.21
8.4
6.9
1.21
1.21
mmol/l
0.08
670
5203
706
5478
1.62
16.24
5.4
5.3
35.07
35.21
g/l
0.24
662
5139
920
7685
1.65
15.14
6.4
5.0
717.88
2148.03
e6/l
0.92
16
116
1001
8552
1.71
15.05
5.4
4.4
13.40
13.02
mm/h
0.32
942
7970
175
940
1.99
14.66
3.8
3.2
9.92
10.91
g/l
2.04
161
866
26
23
11.51
14.31
1.2
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
30
61
5.01
14.09
1.2
1.1
—
—
—
0
0
557
4195
1.57
13.73
5.2
4.2
10.96
8.30
mg/mmol
0.71
370
2683
28
55
5.18
13.67
1.1
1.2
—
—
—
0
0
566
4286
1.56
13.58
4.3
3.5
7.24
7.58
mmol/l
1.05
470
3620
24
43
5.67
12.92
1.1
1.1
—
—
—
0
0
764
6225
1.54
12.88
4.9
4.1
0.02
0.24
estimate
0.46
142
1274
1021
8934
1.63
12.18
10.3
8.5
85.59
80.05
u/l
1.48
969
8470
194
1146
1.81
12.06
3.3
2.3
354.83
384.18
nmol/l
1.27
183
1058
748
6116
1.52
12.04
4.9
4.1
0.00
0.00
estimate
0.50
157
1337
244
1541
1.72
12.03
7.4
7.8
0.99
0.95
mmol/l
0.05
197
1275
44
135
3.34
11.98
1.3
1.7
—
—
—
0
0
808
6720
1.52
11.96
12.1
9.7
4.54
4.19
e9/l
1.87
705
5833
20
15
13.52
11.95
1.1
1.0
5.73
6.46
mg/g
0.36
20
15
29
66
4.47
11.94
1.2
1.1
—
—
—
0
0
755
6192
1.51
11.93
4.9
4.1
0.00
3.85
estimate
1.08
161
1365
420
3044
1.56
11.86
5.0
4.4
89.82
87.02
%
1.62
411
2985
189
1120
1.80
11.61
3.1
3.0
66.33
66.25
g/l
0.04
171
1032
244
1556
1.70
11.58
7.5
7.8
5.19
5.10
kpa
0.54
230
1496
244
1557
1.70
11.55
7.5
7.8
12.48
12.04
kpa
0.59
229
1499
267
1756
1.65
11.24
6.4
6.2
1.05
1.04
mmol/l
0.18
248
1629
396
2862
1.55
11.20
3.3
2.7
4.09
5.43
e6/l
2.16
362
2620
75
319
2.43
11.20
1.8
2.2
11.90
12.30
mg/l
0.14
70
293
766
6376
1.48
10.72
7.4
6.8
10.82
11.75
umol/l
2.00
740
6088
461
3473
1.50
10.63
5.1
4.2
0.00
0.01
estimate
1.15
146
1228
39
123
3.24
10.19
1.3
1.8
—
—
—
0
0
1191
11014
1.84
9.80
24.0
17.8
23.35
25.79
mg/l
2.00
1039
9199
215
1395
1.65
9.43
7.9
8.2
96.03
95.50
%
1.03
207
1353
21
28
7.60
9.43
1.1
1.1
—
—
—
0
0
67
297
2.32
9.16
2.6
2.5
77.28
119.89
ug/min
0.51
40
174
1124
10272
1.64
9.13
6.4
5.4
1.98
1.97
mu/l
0.09
1039
9438
1212
11337
1.85
8.63
28.9
21.3
139.50
139.61
mmol/l
0.77
1192
11121
515
4089
1.43
8.58
4.5
3.5
40.37
88.18
e6/l
1.60
416
3170
298
2131
1.51
8.52
3.6
3.6
0.81
0.82
mmol/l
0.49
277
2017
1212
11350
1.84
8.41
28.9
21.5
3.99
3.99
mmol/l
0.08
1187
11119
452
3520
1.43
8.32
4.2
3.4
0.23
0.45
e6/l
4.13
358
2630
19
27
7.12
8.26
1.1
1.1
—
—
—
0
0
969
8634
1.46
8.26
5.2
4.3
15.03
14.90
pmol/l
0.86
885
7900
565
4605
1.40
7.92
4.9
4.1
0.00
0.04
estimate
4.08
128
1119
638
5309
1.39
7.89
2.6
2.5
77.64
77.65
nmol/l
0.00
569
4749
13
10
13.11
7.88
1.0
1.0
—
—
—
0
0
28
85
3.34
7.82
5.5
2.1
17.76
21.60
nmol/l
0.83
28
76
38
139
2.79
7.75
2.1
1.6
25.08
32.90
ng/l
0.39
38
139
560
4587
1.38
7.49
5.1
4.1
121.83
113.00
e6/l
0.05
426
3296
303
2230
1.47
7.41
2.0
2.0
—
—
—
0
0
25
75
3.38
7.12
2.1
2.2
—
—
—
0
0
343
2603
1.43
7.08
1.8
1.8
1.44
1.40
mg/l
0.07
278
2035
12
10
12.10
7.08
2.1
2.8
—
—
—
0
0
13
13
10.09
7.04
1.1
1.4
—
—
—
0
0
182
1219
1.57
6.92
7.0
7.7
9.92
10.40
mmol/l
0.39
173
1170
275
2028
1.45
6.58
3.0
2.7
2.16
2.28
g/l
2.85
254
1883
290
2170
1.43
6.40
3.0
2.7
12.19
12.68
umol/l
0.56
265
2015
12
13
9.30
6.29
1.2
1.3
—
—
—
0
0
129
814
1.65
6.27
9.0
6.4
25.13
24.45
mmol/l
1.26
121
778
17
32
5.37
6.16
1.0
1.1
—
—
—
0
0
255
1887
1.44
5.94
3.0
2.7
22.70
22.48
%
0.08
237
1763
128
818
1.63
5.92
8.1
10.0
24.16
24.32
mmol/l
0.21
123
802
17
34
5.05
5.88
1.1
1.2
—
—
—
0
0
232
1692
1.45
5.84
1.9
1.9
—
—
—
0
0
639
5498
1.31
5.61
2.3
2.2
98.95
94.66
pmol/l
1.17
319
2940
16
32
5.05
5.57
1.1
1.2
—
—
—
0
0
16
32
5.05
5.57
1.0
1.1
—
—
—
0
0
67
362
1.90
5.56
1.7
1.5
0.06
23.63
iu/ml
0.49
16
51
57
292
2.00
5.52
1.6
1.8
3.26
24.65
iu/l
0.51
25
111
81
466
1.79
5.51
3.8
4.0
54.09
61.90
mg/l
0.20
69
396
380
3041
1.35
5.50
3.1
2.5
—
—
—
0
0
81
467
1.78
5.47
3.8
4.0
47.31
70.67
mg/l
0.42
70
398
19
58
3.31
5.31
1.0
1.1
1343.37
1443.22
miu/ml
0.18
19
58
640
5544
1.30
5.20
3.3
2.9
—
—
estimate
—
0
0
51
257
2.02
5.18
2.8
1.8
0.73
0.87
nmol/l
0.89
40
213
306
2393
1.36
5.09
4.3
4.3
549.20
406.31
ng/l
0.18
256
1950
106
672
1.63
5.08
1.6
1.5
—
—
—
0
0
187
1344
1.46
5.06
4.8
3.8
2.09
1.90
mmol/l
0.34
154
1150
10
12
8.39
5.06
1.1
1.3
—
—
—
0
0
341
2716
1.34
5.03
5.5
4.2
1.02
1.57
kg/l
0.50
230
1830
477
3990
1.31
4.98
3.5
3.4
1397.73
1503.93
ng/l
0.21
421
3458
26
100
2.63
4.91
2.3
2.4
615.94
640.06
ml
0.16
18
63
10
13
7.74
4.85
1.3
1.3
—
—
—
0
0
1115
10484
1.41
4.83
9.4
6.8
43.63
39.73
mmol/mol
19.10
1027
9768
822
7398
1.29
4.82
3.8
3.4
60.09
50.94
u/l
1.05
770
6953
193
1410
1.43
4.78
3.1
3.0
6.15
8.12
umol/l
1.44
173
1265
191
1396
1.43
4.72
4.6
3.8
5.85
5.84
kpa
0.06
181
1359
459
3844
1.30
4.68
3.4
2.7
64.85
81.45
u/l
0.35
426
3566
9
11
8.23
4.56
1.0
1.2
—
—
—
0
0
212
1591
1.40
4.51
1.9
1.9
—
—
—
0
0
33
149
2.25
4.46
10.5
5.8
8.52
6.95
mmol/l
1.14
24
123
1218
11683
1.56
4.40
31.3
23.3
82.77
80.32
umol/l
1.23
1204
11549
164
1183
1.44
4.35
4.2
3.3
4.46
4.51
kpa
0.13
152
1149
1206
11550
1.52
4.32
16.5
12.6
26.18
25.93
u/l
0.20
1165
11220
45
233
1.96
4.29
1.4
1.7
—
—
—
0
0
280
2218
1.33
4.21
4.0
3.1
1.24
1.08
e6/l
0.33
158
1214
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
74
451
1.68
4.17
2.5
3.0
0.39
0.36
iu/ml
0.33
29
245
140
989
1.46
4.15
4.2
3.9
96.53
92.93
ng/l
0.14
126
851
278
2210
1.33
4.07
1.8
1.8
1117.62
1185.30
nmol/l
0.66
219
1677
1120
10610
1.37
4.02
22.9
17.2
77.55
78.29
ml/min/173m2
0.53
1059
9883
13
31
4.22
4.01
1.2
1.1
—
—
—
0
0
69
418
1.69
3.99
3.8
3.8
4.06
4.27
ratio
0.03
39
235
130
913
1.47
3.98
3.6
4.0
5.26
5.16
kpa
0.80
123
884
497
4271
1.26
3.97
3.4
3.6
2.35
2.35
mmol/l
0.11
435
3860
59
343
1.75
3.95
1.7
1.4
0.24
0.24
g/l
0.14
54
326
29
131
2.24
3.94
4.4
2.8
—
—
—
0
0
114
782
1.50
3.92
3.2
3.9
1.82
1.83
mmol/l
0.00
83
599
20
76
2.66
3.91
2.6
2.9
—
—
—
0
0
312
2544
1.30
3.78
1.4
1.3
1.56
1.45
u/ml
0.06
86
684
282
2272
1.31
3.73
1.8
1.5
2.48
2.52
g/l
0.09
180
1380
124
879
1.45
3.63
7.4
9.0
24.80
24.80
mmol/l
0.01
124
874
453
3889
1.25
3.57
3.4
3.4
36.63
33.41
u/l
0.44
429
3671
60
362
1.69
3.55
1.8
1.6
—
—
—
0
0
51
294
1.76
3.54
1.5
3.0
27.53
33.58
umol/l
1.18
45
257
82
536
1.56
3.53
2.6
2.6
4.04
3.72
g/l
0.38
73
486
153
1133
1.40
3.52
2.7
2.5
6.54
7.37
ug/l
0.15
134
1018
133
961
1.43
3.52
3.4
2.9
63.98
64.28
ml/min/173m2
0.03
64
413
82
537
1.56
3.51
2.6
2.6
7.52
7.40
g/l
0.28
73
486
82
537
1.56
3.51
2.6
2.6
4.25
4.17
g/l
0.21
73
486
199
1540
1.34
3.49
5.7
4.3
237.74
247.50
u/l
0.47
188
1467
57
341
1.70
3.48
1.5
1.6
—
—
—
0
0
395
3352
1.25
3.42
2.7
2.3
2.93
2.93
mg/l
0.01
349
2872
314
2598
1.27
3.36
1.8
1.8
442.49
18762075.22
pmol/l
1.51
250
2148
107
752
1.46
3.29
8.5
10.4
15.82
15.82
%
0.01
101
724
178
1367
1.35
3.28
9.8
7.7
—
—
—
0
0
24
109
2.22
3.26
1.5
1.5
—
—
—
0
0
24
109
2.22
3.26
1.5
1.5
—
—
—
0
0
24
109
2.22
3.26
1.5
1.5
—
—
—
0
0
251
2027
1.29
3.24
1.3
1.3
29.98
33.63
iu/ml
0.13
62
625
58
356
1.66
3.24
2.1
2.7
96.74
91.27
%
1.22
58
344
602
5377
1.22
3.17
3.4
3.1
174.81
136.20
ug/l
1.26
558
4971
26
124
2.12
3.15
1.2
1.2
—
—
—
0
0
86
585
1.50
3.12
1.7
1.8
2.91
1.89
ug/l
0.25
72
523
15
56
2.70
3.06
1.4
1.8
75.00
92.22
umol/l
—
8
36
159
1215
1.35
3.03
2.3
2.3
0.21
0.21
g/l
0.03
142
1132
13
45
2.91
3.03
1.2
1.0
—
—
—
0
0
16
63
2.56
2.96
1.5
2.9
560.06
1454.32
u/ml
1.37
16
63
8
17
4.73
2.92
1.1
1.1
—
—
—
0
0
65
423
1.56
2.90
1.2
1.2
0.33
1.21
u/ml
—
9
27
187
1475
1.31
2.88
5.1
5.1
34.15
32.56
%
1.05
137
978
528
4693
1.21
2.83
2.3
1.9
1.33
1.33
mmol/l
0.06
440
3897
378
3250
1.23
2.83
4.1
3.6
1.94
0.04
estimate
0.48
129
1054
38
216
1.78
2.82
1.2
1.2
—
281.25
—
0
16
48
293
1.66
2.78
2.2
1.5
11.39
8.91
u/l
0.51
38
222
1225
11894
1.42
2.75
36.7
26.8
248.77
246.05
e9/l
0.72
1204
11647
1225
11895
1.42
2.74
36.5
26.7
91.11
91.38
fl
1.34
1215
11758
52
326
1.62
2.72
2.0
1.5
—
—
—
0
0
1225
11897
1.42
2.72
37.2
27.3
39.86
40.06
%
0.59
1214
11752
1225
11897
1.42
2.72
36.6
26.7
4.45
4.45
e12/l
0.15
1199
11613
1225
11898
1.42
2.71
36.6
26.8
7.20
6.81
e9/l
3.34
1198
11612
1225
11899
1.41
2.69
36.8
27.0
133.36
134.30
g/l
1.31
1216
11761
8
19
4.23
2.68
4.9
1.3
—
—
—
0
0
64
424
1.54
2.66
1.5
1.3
—
—
—
0
0
154
1202
1.32
2.57
2.7
2.7
65.56
69.40
e9/l
0.87
121
899
49
310
1.60
2.50
1.9
2.5
128.63
128.16
g/l
0.05
41
248
364
3155
1.21
2.48
3.6
3.0
348.02
350.51
umol/l
0.17
316
2761
22
109
2.04
2.47
1.3
1.3
—
—
—
0
0
72
499
1.47
2.44
2.8
2.7
2.88
3.00
g/l
0.35
63
448
11
38
2.91
2.41
1.2
1.3
—
—
—
0
0
68
967
0.69
2.39
1.6
2.0
3.44
3.53
ratio
0.17
45
770
301
2569
1.22
2.39
3.1
3.1
2.46
2.46
mmol/l
0.04
255
2313
26
139
1.89
2.37
1.2
1.4
—
—
—
0
0
8
22
3.65
2.36
1.0
1.4
—
—
—
0
0
1112
10694
1.25
2.34
6.1
5.4
6.45
6.01
mmol/l
10.86
1025
9758
246
2060
1.24
2.34
4.2
3.2
2.56
2.09
e6/l
0.31
117
1052
65
448
1.47
2.28
1.8
1.8
—
—
—
0
0
85
619
1.40
2.23
4.1
3.2
25.07
25.32
mmol/l
0.32
80
596
147
1167
1.29
2.19
2.9
2.5
32.59
39.85
u/l
0.80
116
973
39
242
1.63
2.18
2.1
2.2
216.97
4341.01
u/l
2.18
12
100
86
631
1.39
2.17
1.8
1.9
1.68
1.51
g/l
0.78
76
571
7
19
3.70
2.15
1.0
1.2
—
—
—
0
0
44
283
1.57
2.13
1.4
1.5
—
—
—
0
0
123
958
1.31
2.11
1.9
1.7
—
—
—
0
0
50
333
1.52
2.09
4.1
3.5
2.23
1.82
index
0.23
30
182
5
10
5.01
2.07
1.2
1.1
—
—
—
0
0
30
176
1.72
2.07
1.4
1.6
—
—
—
0
0
19
96
1.99
2.06
6.3
5.6
311.90
32.28
u/ml
—
5
33
414
3690
1.18
2.02
1.8
1.8
20.01
20.17
nmol/l
0.07
350
3107
6
16
3.76
1.93
1.8
1.9
—
—
—
0
0
6
16
3.76
1.93
10.0
12.9
4.78
5.26
mmol/l
—
6
16
84
629
1.36
1.90
4.1
3.9
1.02
1.02
ratio
0.61
75
587
1072
10329
1.20
1.87
5.1
4.4
1.35
1.28
mmol/l
1.80
983
9441
49
334
1.49
1.86
1.5
1.6
—
—
—
0
0
66
477
1.40
1.85
2.4
2.7
10.60
10.68
g/l
0.04
57
422
85
641
1.35
1.85
3.8
3.5
4.42
4.51
pmol/l
0.33
78
563
1137
11023
1.23
1.83
7.1
6.0
2.45
2.63
mmol/l
9.76
1063
10187
68
498
1.39
1.78
3.3
4.4
25.20
24.86
mmol/l
0.47
61
467
682
6363
1.15
1.75
2.8
2.8
—
—
—
0
0
65
475
1.39
1.73
3.1
2.8
2.17
1.34
g/l
0.40
54
405
43
291
1.49
1.71
1.2
1.3
—
—
—
0
0
51
712
0.70
1.68
1.4
1.8
3.34
3.49
mmol/l
0.25
29
522
1117
10829
1.21
1.68
6.2
5.3
4.33
4.53
mmol/l
8.87
1046
10060
1111
10767
1.20
1.67
6.0
5.2
1.41
1.44
mmol/l
1.86
1035
9921
108
857
1.28
1.66
4.4
3.3
128.53
128.39
g/l
0.02
100
833
95
742
1.30
1.65
4.1
2.8
1.14
1.18
%
0.23
90
737
107
850
1.28
1.63
1.9
1.7
—
—
—
0
0
5
14
3.58
1.61
15.6
8.1
0.50
0.36
umol/l
—
5
14
5
15
3.34
1.52
1.2
1.5
—
—
—
0
0
7
27
2.60
1.51
1.3
1.8
—
—
—
0
0
219
1895
1.19
1.51
1.3
1.3
14.76
12.59
u/ml
0.14
80
704
11
51
2.17
1.50
1.5
1.6
—
—
—
0
0
13
66
1.98
1.43
3.3
2.4
—
—
—
0
0
6
22
2.73
1.43
3.3
2.3
—
—
—
0
0
6
22
2.73
1.43
3.3
2.3
—
—
—
0
0
383
3474
1.14
1.43
4.6
4.7
22.43
21.35
%
0.58
181
1751
121
995
1.24
1.41
4.9
4.3
1.23
1.22
mmol/l
0.03
103
862
944
9072
1.14
1.40
29.2
21.9
13.83
13.73
%
1.23
933
8946
22
134
1.65
1.39
1.6
2.0
—
2413.33
—
0
6
19
111
1.72
1.39
1.5
1.8
7.54
3.98
mg/l
0.43
19
106
469
4319
1.13
1.38
6.0
5.8
2.92
2.94
ug/l
0.01
420
3888
9
41
2.20
1.37
1.8
1.3
—
—
—
0
0
12
61
1.98
1.33
6.5
3.5
0.71
1.24
%
0.59
12
61
23
144
1.61
1.32
1.1
1.3
362.81
342.20
pmol/l
0.07
16
125
64
492
1.32
1.29
2.1
1.9
—
—
—
0
0
35
243
1.45
1.28
1.3
1.5
—
—
—
0
0
10
48
2.09
1.28
4.8
1.9
40.11
39.86
g/l
—
10
48
36
253
1.43
1.25
6.9
3.9
26.33
29.12
mg/l
0.18
25
177
8
36
2.23
1.24
1.9
1.3
—
—
—
0
0
8
36
2.23
1.24
1.3
1.3
107.75
108.87
%
—
8
30
5
19
2.64
1.21
1.2
1.1
—
—
—
0
0
17
101
1.69
1.20
1.2
1.4
14.12
14.39
u/l
0.06
17
96
15
86
1.75
1.19
1.5
1.2
—
—
—
0
0
15
86
1.75
1.19
1.5
1.2
—
—
—
0
0
27
181
1.50
1.19
1.1
1.1
6852.98
29.52
iu/ml
—
5
37
10
50
2.01
1.16
1.5
1.6
—
—
—
0
0
10
50
2.01
1.16
1.5
1.6
—
—
—
0
0
43
319
1.36
1.12
1.5
1.3
—
—
—
0
0
23
151
1.53
1.12
1.1
1.2
2.18
3.47
u/ml
0.40
11
53
23
152
1.52
1.09
1.2
1.0
—
—
—
0
0
8
41
1.96
1.09
1.6
2.3
0.59
0.62
mmol/l
—
8
41
48
367
1.32
1.04
1.9
1.6
—
—
—
0
0
36
263
1.38
1.04
8.1
6.3
106.35
105.08
mmol/l
0.93
31
238
23
154
1.50
1.04
1.1
1.3
0.67
12.29
nmol/l
0.50
23
146
28
197
1.43
1.00
1.2
1.5
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
49
380
1.30
0.98
1.5
1.5
252.65
257.75
ug/g
0.08
34
229
15
92
1.64
0.97
2.0
2.3
22.00
32.50
mg/l
—
10
66
33
242
1.37
0.95
1.5
1.5
—
—
—
0
0
7
37
1.90
0.94
1.1
1.2
—
—
—
0
0
12
70
1.72
0.92
1.3
1.5
0.84
1.29
nmol/l
—
5
50
11
63
1.75
0.90
1.6
1.6
—
—
—
0
0
11
63
1.75
0.90
1.6
1.6
—
—
—
0
0
11
63
1.75
0.90
1.6
1.6
—
—
—
0
0
11
63
1.75
0.90
1.6
1.6
—
—
—
0
0
61
493
1.25
0.90
2.1
2.9
—
—
—
0
0
39
297
1.32
0.90
1.4
1.6
—
—
—
0
0
117
1011
1.17
0.88
2.8
2.3
12.74
12.91
nmol/l
0.07
109
908
123
1069
1.17
0.86
3.9
2.4
0.30
0.50
e6/l
0.97
118
1018
49
388
1.27
0.86
5.4
4.8
1.66
1.60
mg/l
0.19
42
349
57
460
1.25
0.86
2.2
1.6
7.99
7.08
iu/ml
0.13
17
104
148
1306
1.15
0.85
3.8
3.6
—
—
—
0
0
34
256
1.34
0.85
1.3
1.3
—
—
—
0
0
34
256
1.34
0.85
1.3
1.3
—
—
—
0
0
13
203
0.64
0.84
1.5
1.5
—
—
—
0
0
14
88
1.60
0.84
1.0
1.0
280.00
289.91
mg/l
0.17
14
76
6
31
1.94
0.84
1.0
1.5
14.83
14.47
pmol/l
—
6
24
12
73
1.65
0.81
1.1
1.2
—
—
—
0
0
85
721
1.19
0.80
1.3
1.2
153.41
147.77
u/ml
0.05
33
270
0
27
0.00
0.77
0.0
1.2
—
1.21
—
0
18
27
200
1.36
0.76
1.4
1.4
—
—
—
0
0
156
1394
1.14
0.76
2.2
2.4
204.12
135.03
ug/g
0.87
115
1106
65
541
1.21
0.76
1.1
1.1
—
0.90
—
0
5
5
24
2.09
0.74
1.0
1.1
1.21
1.18
mmol/l
—
5
24
7
38
1.85
0.73
2.1
2.8
4.85
4.82
kpa
—
7
38
9
56
1.61
0.72
1.0
1.1
—
—
—
0
0
55
455
1.22
0.69
1.6
1.7
0.35
0.35
mg/l
0.03
22
211
9
145
0.62
0.69
1.1
1.7
—
—
—
0
0
10
157
0.63
0.69
1.2
1.4
6.88
6.46
mmol/l
—
10
150
13
85
1.53
0.69
1.5
1.9
—
—
—
0
0
12
77
1.56
0.68
1.2
1.6
11.86
5.33
u/l
—
7
66
49
402
1.23
0.67
3.4
2.6
0.00
0.02
g/l
0.97
44
357
23
306
0.75
0.67
4.7
3.4
0.69
0.83
nmol/l
1.60
18
254
7
43
1.63
0.67
1.0
1.1
—
—
—
0
0
40
322
1.25
0.65
1.4
1.1
—
—
—
0
0
51
422
1.22
0.65
2.3
1.4
25.26
25.79
iu/l
0.04
42
353
5
29
1.73
0.64
1.8
3.7
4.40
6.10
ug/l
—
5
29
28
216
1.30
0.63
1.4
1.4
180.88
156.59
au/ml
—
8
59
11
71
1.55
0.62
1.4
1.8
68.28
108.17
ng/l
2.16
11
71
20
147
1.37
0.62
2.2
2.4
25.14
24.02
mg/l
—
7
57
58
490
1.19
0.61
1.3
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
16.07
—
0
14
6
35
1.72
0.57
1.3
1.7
—
—
—
0
0
147
1338
1.11
0.56
4.3
4.3
110.36
22.38
ug/l
0.39
125
1102
58
495
1.18
0.56
2.9
3.5
49.55
3020.74
u/ml
0.85
52
424
6
37
1.62
0.55
1.0
1.3
—
9.13
—
0
14
6
38
1.58
0.54
2.3
2.8
9.48
9.79
kpa
—
6
38
128
1410
0.90
0.54
1.4
1.5
—
—
—
0
0
30
240
1.26
0.54
1.2
1.2
66.62
44.45
u/ml
—
6
26
39
322
1.22
0.53
1.4
1.1
—
—
—
0
0
15
108
1.39
0.53
1.3
1.6
—
—
—
0
0
13
91
1.43
0.53
1.2
1.1
116.92
109.09
pmol/l
0.16
13
91
47
397
1.19
0.52
3.6
2.6
0.00
0.00
g/l
-0.00
42
341
37
306
1.22
0.51
1.3
1.2
—
—
—
0
0
9
65
1.39
0.50
3.0
3.8
—
—
—
0
0
22
171
1.29
0.50
1.6
1.6
—
—
—
0
0
12
167
0.72
0.49
1.2
1.5
1.32
1.19
ratio
—
7
103
12
167
0.72
0.49
1.2
1.5
0.76
0.95
ratio
—
7
103
12
167
0.72
0.49
1.2
1.5
1.55
1.14
ratio
—
7
103
12
166
0.72
0.48
1.2
1.5
—
—
—
0
0
12
166
0.72
0.48
1.1
1.1
—
6.00
—
0
5
13
177
0.73
0.47
1.1
1.1
—
—
—
0
0
10
68
1.47
0.47
1.4
1.4
—
—
—
0
0
916
8987
1.06
0.46
31.6
22.8
331.88
332.10
g/l
0.30
909
8936
83
927
0.89
0.46
2.2
2.1
—
—
—
0
0
113
1029
1.11
0.45
3.0
3.2
245.60
231.90
ng/l
0.07
105
955
14
103
1.36
0.45
1.1
1.0
—
—
—
0
0
5
32
1.56
0.42
2.4
1.4
8.74
9.13
ug/l
—
5
32
5
33
1.52
0.41
1.6
1.5
—
—
—
0
0
183
1717
1.08
0.39
1.4
1.5
—
—
—
0
0
25
302
0.82
0.39
1.4
1.5
—
—
—
0
0
42
363
1.16
0.39
1.2
1.3
—
—
—
0
0
11
80
1.38
0.38
1.0
1.7
1.18
1.05
promille
—
6
68
272
2594
1.06
0.37
3.2
3.4
0.79
0.77
ug/l
0.10
190
1745
14
107
1.31
0.37
1.0
1.1
101.36
97.55
%
0.25
14
100
21
172
1.22
0.34
1.6
1.7
—
—
—
0
0
14
109
1.29
0.33
1.3
1.3
—
—
—
0
0
32
370
0.86
0.32
1.7
1.7
2.54
4.08
mg/l
1.00
24
285
19
157
1.21
0.29
1.1
1.4
—
—
—
0
0
19
157
1.21
0.29
1.1
1.4
—
—
—
0
0
19
157
1.21
0.29
1.0
1.2
2.88
4.97
u/ml
—
8
73
30
344
0.87
0.28
1.4
1.4
—
—
—
0
0
10
76
1.32
0.28
1.2
1.6
—
—
—
0
0
8
62
1.29
0.28
3.5
7.3
—
72.50
—
0
16
17
140
1.22
0.27
1.0
1.1
124.00
116.56
%
0.40
17
126
58
529
1.10
0.26
1.1
1.1
—
—
—
0
0
9
74
1.22
0.25
1.2
1.6
—
—
—
0
0
11
87
1.27
0.24
1.2
1.5
—
—
—
0
0
12
97
1.24
0.23
1.1
2.4
3.80
1.59
u/field
—
5
54
7
91
0.77
0.22
1.1
1.4
—
426.00
—
0
10
79
844
0.93
0.22
2.1
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.01
—
0
6
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
96
910
1.06
0.19
1.5
1.5
—
—
—
0
0
70
744
0.94
0.18
1.4
1.3
104.57
240.50
u/ml
2.20
64
685
7
61
1.15
0.17
1.1
1.2
108.40
162.16
pmol/l
—
7
61
27
243
1.11
0.17
1.4
1.4
—
—
—
0
0
16
139
1.15
0.16
3.9
3.6
—
—
—
0
0
33
302
1.10
0.16
1.4
1.5
—
—
—
0
0
8
71
1.13
0.16
4.1
1.5
—
—
—
0
0
8
71
1.13
0.16
4.1
1.5
—
—
—
0
0
6
80
0.75
0.15
1.0
1.1
—
—
—
0
0
10
119
0.84
0.15
1.1
1.1
—
56.60
—
0
5
51
480
1.07
0.14
2.1
1.9
—
—
—
0
0
17
151
1.13
0.13
1.1
1.4
—
—
—
0
0
17
151
1.13
0.13
1.1
1.4
—
—
—
0
0
43
404
1.07
0.12
2.0
1.8
—
—
—
0
0
17
152
1.12
0.12
1.1
1.4
—
—
—
0
0
36
337
1.07
0.11
2.1
1.8
41.50
41.29
nmol/l
0.01
36
322
5
44
1.14
0.10
1.2
1.2
80.60
163.36
iu/ml
—
5
44
17
155
1.10
0.09
1.1
1.4
—
—
—
0
0
6
56
1.07
0.08
1.8
1.3
251.17
483.22
u/l
—
6
50
12
107
1.12
0.08
1.0
1.0
0.18
0.57
u/ml
—
5
37
12
108
1.11
0.07
1.5
1.1
—
166.84
—
0
19
16
147
1.09
0.07
1.0
1.1
—
—
—
0
0
7
80
0.87
0.07
2.6
1.4
79.71
84.74
umol/l
—
7
80
14
153
0.91
0.07
1.1
1.1
—
1.88
—
0
21
33
314
1.05
0.07
1.2
1.2
3.90
8.22
u/ml
—
8
49
11
122
0.90
0.07
1.5
1.7
—
—
—
0
0
124
1265
0.98
0.06
1.8
1.8
1.62
1.52
%
0.65
102
1077
32
305
1.05
0.06
1.0
1.2
1.61
1.53
g/l
0.85
32
305
10
90
1.11
0.05
1.2
1.3
—
—
—
0
0
11
101
1.09
0.04
1.0
1.3
—
—
—
0
0
20
191
1.05
0.03
1.0
1.1
0.26
1.89
u/ml
—
9
112
52
531
0.98
0.03
3.2
3.3
36.05
93.17
u/ml
1.18
47
513
27
279
0.97
0.02
1.1
1.3
239.09
245.99
miu/ml
0.04
11
123
33
322
1.03
0.01
1.1
1.2
0.89
0.90
g/l
0.07
33
322
16
153
1.05
0.01
1.0
1.1
0.09
1.58
u/ml
—
7
83
10
106
0.94
0.01
1.0
1.6
66.54
53.31
ug/l
—
10
106
12
114
1.05
0.00
1.2
1.2
14.75
12.75
u/l
0.21
12
104
23
226
1.02
0.00
1.3
1.3
213.47
262.77
u/ml
0.39
17
119
27
266
1.02
0.00
2.0
1.9
190.41
210.69
pmol/l
0.65
27
251
31
312
0.99
0.00
1.2
1.2
1.14
2.30
u/ml
—
5
26
10
101
0.99
0.00
1.0
1.1
—
—
—
0
0
33
325
1.02
0.00
1.4
1.6
16296.59
14656.12
e6/l
0.07
22
231
0
8
0.00
0.00
0.0
1.1
—
62.00
—
0
8
8
82
0.98
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
82
0.98
0.00
1.1
1.4
—
—
—
0
0
8
82
0.98
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
6.6
—
—
—
0
0
8
82
0.98
0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.8
—
—
—
0
0
6
59
1.02
-0.00
1.7
2.9
—
40740.36
—
0
11
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.3
—
26.00
—
0
9
0
9
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.1
—
395.43
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
-0.00
1.0
1.1
—
—
—
0
0
8
81
0.99
-0.00
1.0
1.1
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
3.00
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint H7_PARASTRA6 and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PARASTRA6 | 1.239 [1.11, 1.39] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.18 |
During the follow-up period (1.1.1998 — 31.12.2019), 956 out of 3610 females with H7_PARASTRA6 died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PARASTRA6 | 1.369 [1.21, 1.55] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 985 out of 3415 males with H7_PARASTRA6 died.
Mortality risk
Mortality risk for people of age
years, who have H7_PARASTRA6.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.088% | 0.26% |
| 5 | 0.674% | 1.56% |
| 10 | 1.642% | 4.144% |
| 15 | 3.278% | 7.631% |
| 20 | 5.817% | 12.723% |
Relationships between endpoints
↥Index endpoint: H7_PARASTRA6 – Sixth [abducent] nerve palsy
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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