Mixed hyperlipidaemia

E4_HYPERLIPMIX

obsolete_familial combined hyperlipidemia: ['A type of familial lipid metabolism disorder characterized by a variable pattern of elevated plasma CHOLESTEROL and/or TRIGLYCERIDES. Multiple genes on different chromosomes may be involved, such as the major late transcription factor (UPSTREAM STIMULATORY FACTORS) on CHROMOSOME 1.']

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E78.2
  • Hospital discharge: ICD-9 2722
  • Cause of death: ICD-10 E78.2
  • Cause of death: ICD-9 2722

2 out of 7 registries used, show all original rules.

1836

4. Check minimum number of events

None

1836

5. Include endpoints

None

1836

6. Filter based on genotype QC (FinnGen only)

1621

Control definitions (FinnGen only)

Control exclude
E4_METABOLIA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E78

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9795 3468 6263
Only index persons 8546 3081 5465
Unadjusted period prevalence (%)
Whole population 0.15 0.10 0.17
Only index persons 0.17 0.11 0.21
Median age at first event (years)
Whole population 57.21 62.08 54.43
Only index persons 56.64 61.35 53.98

-FinnGen-

Key figures

All Female Male
Number of individuals 1621 595 1026
Unadjusted period prevalence (%) 0.38 0.21 0.47
Median age at first event (years) 56.69 59.08 55.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1673
Matched controls
16730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C10AB05
ATC
fenofibrate; oral
28.0
319.9
222
91
E66.00
ICD-10 Finland
Metabolic syndrome
12.3
307.7
356
360
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
6.9
307.7
923
2532
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
16.2
307.7
360
278
E78.29
ICD-10 Finland
Other mixed hyperlipidaemia
4614.0
307.7
1228
10
E78.2
ICD-10 Finland
Mixed hyperlipidaemia
1746.8
305.8
288
*
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
45.6
295.6
176
43
103
Kela drug reimbursment
Diabetes, insulin-treated
6.0
293.6
938
2952
A10BA02
ATC
metformin; oral
5.5
264.5
943
3194
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
10.2
260.2
325
388
215
Kela drug reimbursment
Diabetes, non-insulin-treated
5.4
259.2
830
2564
C10AX09
ATC
ezetimibe; oral
6.0
257.1
623
1512
C10AB02
ATC
bezafibrate; oral
31.2
247.7
164
58
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
5.8
240.3
591
1444
C10AA05
ATC
atorvastatin; oral
5.0
219.0
1144
5027
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
5.1
216.7
633
1773
C10AA01
ATC
simvastatin; oral
4.8
210.9
1102
4799
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
7.6
200.3
318
500
A10AE04
ATC
insulin glargine; parenteral
6.2
198.6
400
802
T90
ICPC
Diabetes non-insulin dependent
4.5
196.2
768
2669
A10AB05
ATC
insulin aspart; parenteral
6.9
188.2
328
568
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
22.0
178.2
134
66
C01DA14
ATC
isosorbide mononitrate; oral
4.8
177.1
511
1391
I25.1
ICD-10 Finland
Atherosclerotic heart disease
4.3
175.5
683
2331
E78.21
ICD-10 Finland
Remnant hyperlipidemia
+∞
175.1
165
*
A10AC01
ATC
insulin (human); parenteral
6.5
166.7
307
559
81
HP
Angiography of the heart and coronary arteries
7.0
164.6
280
470
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
5.2
161.0
398
948
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
6.7
148.8
260
447
I25.2
ICD-10 Finland
Old myocardial infarction
6.1
146.5
284
541
2722A
ICD-9 Finland
Disorders of lipoid metabolism, Mixed hyperlipidaemia
+∞
143.9
136
*
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
6.8
142.1
243
408
A10AE05
ATC
insulin detemir; parenteral
7.0
138.4
228
368
205
Kela drug reimbursment
Chronic hypertension
3.5
137.2
747
3103
I10
ICD-10 Finland
Essential (primary) hypertension
4.3
132.2
1352
8258
C10AA07
ATC
rosuvastatin; oral
3.4
129.7
824
3734
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
3.5
127.8
669
2688
B01AC04
ATC
clopidogrel; oral
3.9
126.4
470
1508
B04AB02, ,
ATC
13.2
124.3
121
98
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.5
122.7
618
2414
C10AB04
ATC
gemfibrozil; oral
22.3
122.6
91
43
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
8.0
120.4
172
236
A10BJ06
ATC
semaglutide; parenteral
6.3
118.1
216
386
SPAT1262
SPAT
Handing over of treatment supplies
3.7
117.8
500
1745
A10BH01
ATC
sitagliptin; oral
4.5
116.1
328
856
E11
ICD-10 Finland
Type 2 diabetes mellitus
3.7
115.5
468
1582
C10AA03
ATC
pravastatin; oral
5.3
115.4
256
547
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
5.2
112.8
260
574
E66.01
ICD-10 Finland
Obesity due to excess calories
5.1
112.4
264
592
A10BB12
ATC
glimepiride; oral
5.1
112.4
264
592
C10AA04
ATC
fluvastatin; oral
4.8
109.0
280
676
C03CA01
ATC
furosemide; systemic
3.1
106.0
745
3484
E78.11
ICD-10 Finland
Other hypertriglyceridemia
56.5
106.0
60
11
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
3.4
103.8
504
1897
A10BK03
ATC
empagliflozin; oral
4.1
102.6
335
969
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
8.0
101.3
143
193
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
4.3
100.8
296
791
B04AC02, ,
ATC
29.8
99.2
66
23
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
6.4
98.9
174
298
AN1
HP
Coronary angiography
4.0
97.5
323
942
C07AB02
ATC
metoprolol; systemic
3.1
90.4
506
2051
B04AC04, ,
ATC
22.1
86.2
64
30
C07AB07
ATC
bisoprolol; oral
2.7
84.8
1044
6315
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
12.6
84.5
84
70
A10AD05
ATC
insulin aspart; parenteral
11.3
83.3
89
83
E66.8
ICD-10 Finland
Other obesity
5.9
83.2
159
294
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
6.8
82.7
134
210
160
Kela drug reimbursment
exenatide
9.4
82.4
101
114
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
4.0
82.3
268
767
M04AA01
ATC
allopurinol; systemic
3.3
81.8
389
1424
C10AA02
ATC
lovastatin; oral
6.3
81.4
144
247
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.8
81.0
623
2969
A10BK01
ATC
dapagliflozin; oral
4.1
79.4
241
655
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
8.3
78.6
106
135
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
6.0
75.4
139
248
A10BJ02
ATC
liraglutide; parenteral
7.2
75.3
115
169
C03DA01
ATC
spironolactone; oral
3.3
74.1
329
1150
C08CA01
ATC
amlodipine; oral
2.5
74.0
834
4730
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
7.4
73.5
110
158
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
6.5
71.9
121
197
A10BB01
ATC
glibenclamide; oral
5.3
71.6
151
305
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.3
69.8
196
501
R07.4
ICD-10 Finland
Chest pain, unspecified
2.6
69.6
603
3005
E87.5
ICD-10 Finland
Hyperkalaemia
21.4
69.2
52
25
C09AA02
ATC
enalapril; systemic
2.7
68.8
474
2108
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
9.6
68.8
82
89
A10BX01
ATC
guar gum; oral
5.6
67.9
136
262
A10BG03
ATC
pioglitazone; oral
6.6
66.5
111
179
I20.09
ICD-10 Finland
Unstable angina
4.6
66.2
167
392
XCK10
NOMESCO Finland
Photography of fundus of eye
3.5
65.5
254
812
E86
ICD-10 Finland
Volume depletion
29.4
64.3
43
15
I50.9
ICD-10 Finland
Heart failure, unspecified
2.9
63.6
359
1432
H3600, E113,
ICD-10 Finland
11.2
62.9
67
62
I20.00
ICD-10 Finland
Unstable angina
6.4
62.8
107
176
B01AC06
ATC
acetylsalicylic acid; oral
5.8
62.3
119
219
4019X
ICD-9 Finland
Essential hypertension, Unspecified
5.9
61.0
113
202
211
Kela drug reimbursment
Severe hereditary disorders of lipid metabolism (familial hypercholesterolaemia and type III dyslipoproteinemia)
26.9
61.0
42
16
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
5.2
59.9
128
261
A10AE06
ATC
insulin degludec; parenteral
5.9
59.3
110
197
11
HP
Coronary artery bypass surgery
7.2
58.8
89
129
H36.01
ICD-10 Finland
Diabetic maculopathy
10.7
58.2
64
62
A10BX07
ATC
[U] liraglutide
10.1
57.5
66
68
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
4.2
57.3
165
428
G47.3
ICD-10 Finland
Sleep apnoea
2.4
57.2
529
2674
177
Kela drug reimbursment
Insulin glargine 300 U / ml
8.9
57.1
72
84
82
HP
Single vessel balloon catheter extension
6.9
56.0
88
133
H3601, E113,
ICD-10 Finland
8.7
55.2
71
85
A10AB04
ATC
insulin lispro; parenteral
6.3
55.1
95
158
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
4.6
54.7
138
323
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
6.0
54.3
99
174
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
4.2
54.2
152
386
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
7.6
54.1
78
107
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
4.4
53.9
142
344
N18.8
ICD-10 Finland
Other chronic renal failure
6.6
53.2
87
137
C02AC05
ATC
moxonidine; oral
4.4
52.8
138
332
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
4.5
52.3
136
326
A10AB01
ATC
insulin (human); parenteral
5.9
51.6
96
172
I20.90
ICD-10 Finland
Angina pectoris, unspecified
5.3
51.6
108
216
C09AA05
ATC
ramipril; oral
2.3
50.5
540
2881
C07AG02
ATC
carvedilol; oral
3.8
50.5
168
482
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.9
49.9
78
117
A10BX04
ATC
[U] exenatide
11.1
49.7
53
49
XF402
NOMESCO Finland
ECG with work load test
3.0
49.6
241
876
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
11.1
48.8
52
48
4130B
ICD-9 Finland
Angina pectoris, Angina decubitus[ANGINA PECTORIS (""""EFFORT ANGINA""""),AHTAUTUNUT]
7.2
48.5
73
105
B01AC07
ATC
dipyridamole; systemic
4.3
48.0
132
330
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.5
47.2
174
534
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.2
47.1
133
339
E87.6
ICD-10 Finland
Hypokalaemia
8.6
46.5
60
72
C08CA13
ATC
lercanidipine; oral
2.6
46.4
326
1435
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
10.9
46.3
50
47
B04AB01, ,
ATC
9.8
46.1
54
57
A10AA02, ,
ATC
5.5
45.9
91
173
I25
ICD-10 Finland
Chronic ischaemic heart disease
4.1
45.6
133
347
T89
ICPC
Diabetes insulin dependent
4.7
45.6
110
248
E66.0
ICD-10 Finland
Obesity due to excess calories
10.5
45.0
50
49
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.4
44.9
116
276
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.4
44.8
392
1907
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
6.3
44.6
77
128
I50.0
ICD-10 Finland
Congestive heart failure
3.2
44.6
193
654
162
Kela drug reimbursment
liraglutide
9.0
44.2
55
63
N02AX02
ATC
tramadol; systemic, rectal
2.0
43.7
817
5336
M10.9
ICD-10 Finland
Gout, unspecified
3.1
43.2
196
683
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
43.1
896
6065
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
43.0
369
1776
A11CC03
ATC
alfacalcidol; systemic
6.5
42.9
71
113
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.4
42.7
165
521
H36.00
ICD-10 Finland
Diabetic background retinopathy
8.9
42.4
53
61
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
3.5
42.3
156
478
N03AX16
ATC
[U] pregabalin
2.2
42.2
436
2269
4100X
ICD-9 Finland
Acute myocardial infarction, Of anterolateral wall[INFARCTUS MYOCARDII ACUTUS DEFINITUS,MÄÄRITTELEMÄT]
6.5
42.1
70
112
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
14.4
41.7
38
27
I20.01
ICD-10 Finland
Unstable angina
5.1
41.6
90
185
C10BA02
ATC
simvastatin and ezetimibe; oral, topical
8.9
41.5
52
60
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
8.1
41.5
56
71
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.2
41.2
71
118
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.4
41.1
107
256
R06.0
ICD-10 Finland
Dyspnoea
2.1
40.6
518
2922
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
3.9
40.3
122
327
A10BD07
ATC
metformin and sitagliptin; systemic
3.9
40.0
124
338
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
6.6
38.6
63
99
A10BJ05
ATC
dulaglutide; parenteral
6.0
38.2
69
120
A10AD01
ATC
insulin (human); parenteral
6.8
38.0
60
91
A10BH05
ATC
linagliptin; oral
3.6
37.1
131
390
C03AA03
ATC
hydrochlorothiazide; oral
2.8
36.6
202
782
E78.49
ICD-10 Finland
Other hyperlipidaemia
12.7
35.8
35
28
C09BA02
ATC
enalapril and diuretics; systemic
2.8
35.8
192
732
4120B
ICD-9 Finland
Old myocardial infarction[STATUS POST INFARCTUM CORDIS,AHTAUTUNUT]
7.5
35.3
51
70
AN4
HP
Balloon angioplasty and drug eluding stent
4.6
35.1
85
192
TK800
NOMESCO Finland
Hemodialysis
5.6
34.1
65
119
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
34.1
538
3242
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
34.0
309
1510
4120X
ICD-9 Finland
Old myocardial infarction[STATUS POST INFARCTUM CORDIS,MÄÄRITTELEMÄT]
7.5
34.0
49
67
E78.40
ICD-10 Finland
Familial combined hyperlipidaemia
333.5
33.0
33
*
C08CA02
ATC
felodipine; oral
2.6
32.6
208
865
RD210, ,
NOMESCO Finland
6.9
32.4
50
74
J01FF01
ATC
clindamycin; systemic
2.0
32.0
500
2991
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.8
31.9
168
633
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
31.8
576
3618
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
8.7
31.5
40
47
A02BC02
ATC
pantoprazole; systemic
1.9
31.4
1164
9121
4130X
ICD-9 Finland
Angina pectoris, Angina decubitus[ANGINA PECTORIS (""""EFFORT ANGINA""""),MÄÄRITTELEMÄT]
5.7
31.3
59
107
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.5
30.8
208
888
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
6.6
30.8
50
78
A10BG02
ATC
rosiglitazone; oral
6.0
30.7
55
95
NHQ40
NOMESCO Finland
Amputation of toe
6.5
30.4
50
79
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.9
30.1
91
243
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
29.6
658
4386
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
29.3
443
2607
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.7
28.9
96
274
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
28.4
260
1269
A12AA04
ATC
calcium carbonate; oral
6.5
28.2
46
72
A10BJ01
ATC
exenatide; parenteral
8.1
28.2
38
48
H3603, E113,
ICD-10 Finland
8.5
27.9
36
43
PE1AT
NOMESCO Finland
Femoral artery PTA
7.4
27.6
40
55
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.9
27.6
139
511
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.1
27.5
123
423
4140B
ICD-9 Finland
Other forms of chronic ischaemic heart disease, Coronary atherosclerosis[ATHEROSCLEROSIS ARTER CORON CORDIS,AHTAUTUNUT]
7.8
27.3
38
50
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
5.5
27.2
53
99
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.3
27.2
243
1172
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
4.4
27.1
69
162
C03BA11
ATC
indapamide; oral
4.3
27.0
70
167
Z3231
NOMESCO Finland
Registered nurse
1.9
26.9
463
2832
J01DB01
ATC
cefalexin; oral
2.0
25.8
1355
11439
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
1.9
25.7
391
2294
A10BB07
ATC
glipizide; oral
6.2
25.5
44
73
A28
ICPC
Limited function/disability NOS
2.0
25.5
331
1838
T82
ICPC
Obesity
3.8
25.5
79
215
R07.3
ICD-10 Finland
Other chest pain
2.3
25.5
203
932
ZXD05
NOMESCO Finland
Urgent procedure
1.8
25.5
482
3030
N19
ICD-10 Finland
Unspecified kidney failure
3.6
25.5
87
253
I50.1
ICD-10 Finland
Left ventricular failure
2.9
25.4
121
431
H3601, E103,
ICD-10 Finland
10.5
25.4
28
27
H3600, E103,
ICD-10 Finland
9.5
25.3
30
32
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.6
25.3
161
666
E66.9
ICD-10 Finland
Obesity, unspecified
3.9
25.2
75
198
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
25.2
674
4684
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
5.0
25.2
55
114
N05CF01
ATC
zopiclone; oral
1.8
24.9
549
3609
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
4.5
24.7
61
140
280
Kela drug reimbursment
Clopidogrel
5.8
24.7
45
79
N06AB04
ATC
citalopram; systemic
1.9
24.5
347
1984
A46
ICD-10 Finland
Erysipelas
2.0
24.5
295
1594
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.6
24.3
149
606
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
4.8
24.2
55
118
N06AA09
ATC
amitriptyline; systemic
2.4
24.1
180
803
I20.80
ICD-10 Finland
Other angina pectoris no detected stenosis of coronary artery
5.7
24.0
45
81
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.6
23.9
57
127
3015
Kela drug reimbursment
Alirocumab and evolocumab for the treatment of hypercholesterolaemia and dyslipidaemia
21.0
23.9
35
17
C02DE02, ,
ATC
5.5
23.9
46
85
I20.91
ICD-10 Finland
Angina pectoris, unspecified
5.9
23.7
43
75
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
6.0
23.6
42
72
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
4.5
23.5
58
133
N18.0
ICD-10 Finland
End-stage renal disease
6.7
23.4
37
56
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.9
23.4
113
405
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
6.0
23.1
41
70
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.1
23.1
97
321
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.6
23.0
44
81
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.7
22.9
132
520
C07AB03
ATC
atenolol; systemic
2.7
22.9
127
491
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
5.2
22.7
47
93
FN1CB
NOMESCO Finland
Coronary flow reserve measurement with pressure wire
4.0
22.6
64
163
A10AB06
ATC
insulin glulisine; parenteral
7.1
22.5
34
49
B01AA03
ATC
warfarin; systemic
1.9
22.4
365
2177
N05BA04
ATC
oxazepam; oral
1.8
22.4
424
2651
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
22.3
223
1122
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
22.3
256
1357
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.7
22.2
41
73
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
5.1
22.1
47
95
XF600
NOMESCO Finland
Bloodpressure measurement
2.7
22.1
121
464
Z3226
NOMESCO Finland
Physiotherapist
2.0
22.1
294
1641
L17
ICPC
Foot/toe symptom/complaint
1.7
22.1
491
3214
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
3.4
22.1
79
237
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.4
21.9
164
731
C07AB08
ATC
celiprolol; oral
3.7
21.9
69
190
L28
ICPC
Limited function/disability (L)
1.9
21.9
336
1966
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
21.8
721
5242
R53
ICD-10 Finland
Malaise and fatigue
1.8
21.8
391
2401
A10AA01, ,
ATC
4.6
21.8
52
116
C10AX13
ATC
evolocumab; parenteral
18.7
21.8
33
18
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
18.7
21.8
33
18
C09CA01
ATC
losartan; oral
1.8
21.7
469
3042
C08CA07
ATC
nisoldipine; oral
6.0
21.4
38
65
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
21.4
382
2342
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
21.4
215
1083
A10BD03
ATC
metformin and rosiglitazone; systemic
4.7
21.3
49
106
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
5.5
21.2
41
76
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
21.2
333
1962
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
8.1
20.9
28
35
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
20.8
197
968
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
5.8
20.7
38
67
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
20.7
181
861
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
20.7
576
3993
ZXE00
NOMESCO Finland
One hour or less
1.7
20.7
599
4196
V03AE01
ATC
polystyrene sulfonate; oral
5.7
20.4
38
68
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
20.4
464
3044
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
20.4
303
1751
S97
ICPC
Chronic ulcer skin
2.5
20.2
137
583
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
6.3
20.2
34
55
N06AX16
ATC
venlafaxine; oral
2.1
20.2
214
1098
C08DB01
ATC
diltiazem; oral
2.8
20.2
108
409
EBA00
NOMESCO Finland
Extraction of tooth
1.7
20.2
593
4162
358
Kela drug reimbursment
liraglutide
8.5
20.2
26
31
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
20.1
240
1287
SPAT1263
SPAT
Sampling
1.6
20.1
649
4665
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
20.0
100
366
294
Kela drug reimbursment
Alirocumab and evolocumab for the treatment of hypercholesterolaemia and dyslipidaemia
21.1
20.0
29
14
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
19.9
473
3137
J01DA01
ATC
[U] cefalexin
1.6
19.8
972
7723
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
19.8
245
1329
E78.10
ICD-10 Finland
Familial hypertriglyceridemia
+∞
19.8
19
*
2720X
ICD-9 Finland
Disorders of lipoid metabolism, Pure hypercholesterolaemia[HYPERCHOLESTEROLAEMIA ALIA]
+∞
19.8
19
*
M10
ICD-10 Finland
Gout
2.7
19.8
106
402
C08CA05
ATC
nifedipine; systemic
2.6
19.8
121
491
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
19.7
589
4146
N06AB10
ATC
escitalopram; oral
1.9
19.7
286
1638
R42
ICD-10 Finland
Dizziness and giddiness
1.8
19.7
377
2352
AA1
HP
Conventional CABG
4.7
19.7
46
101
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.6
19.7
122
498
H03AA01
ATC
levothyroxine sodium; systemic
1.8
19.6
330
1980
N06AX11
ATC
mirtazapine; oral
1.7
19.6
537
3698
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
3.9
19.6
58
153
Z49.0
ICD-10 Finland
Preparatory care for dialysis
6.1
19.5
34
57
OAB50, ,
SPAT
2.3
19.5
165
774
C02EA02, ,
ATC
2.8
19.4
97
355
M10.0
ICD-10 Finland
Idiopathic gout
3.0
19.1
86
297
N02BE01
ATC
paracetamol; systemic, rectal
2.0
19.0
1463
13029
N05CD07
ATC
temazepam; oral
2.0
19.0
214
1123
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
18.7
268
1526
61
HP
Catheterization and pressure measurement of the left side of the heart
4.6
18.7
45
101
J01MA02
ATC
ciprofloxacin; systemic
1.6
18.7
647
4707
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
21.1
18.6
27
13
N05BA01
ATC
diazepam; systemic, rectal
2.0
18.6
218
1160
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.9
18.4
90
325
R02
ICPC
Shortness of breath/dyspnoea
2.0
18.2
229
1248
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.7
18.2
58
161
SPAT1336
SPAT
Request for examination
3.3
18.0
69
216
FN2AB
NOMESCO Finland
Percutaneous transluminal coronary angioplasty (PTCA), drug-eluting balloon
4.4
17.9
45
105
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
7.0
17.8
27
39
N06AX21
ATC
duloxetine; oral
2.1
17.8
184
934
5314
FHL
Bypass surgery for four or more vessels
6.1
17.8
31
52
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
18.3
17.8
27
15
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
17.8
207
1098
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
17.6
306
1850
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
4.8
17.6
39
82
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.9
17.5
85
306
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
5.9
17.5
31
53
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
17.4
163
796
C10AC02
ATC
colestipol; oral
42.5
17.3
21
5
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
17.3
116
492
A02BA02
ATC
ranitidine; systemic
1.8
17.1
318
1959
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.0
17.1
75
255
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.9
17.0
250
1433
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
3.3
16.9
64
199
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.4
16.8
120
523
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.5
16.7
27
42
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.3
16.7
127
570
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
16.6
191
1008
AN2
HP
Balloon angioplasty, including several vessels
3.5
16.5
57
167
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
16.3
576
4178
G63.2
ICD-10 Finland
Diabetic polyneuropathy
14.4
16.3
27
19
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.3
16.2
61
189
N05AH04
ATC
quetiapine; oral
1.8
16.2
271
1616
I50
ICD-10 Finland
Heart failure
3.2
16.1
64
205
310
Kela drug reimbursment
Orlistat, sibutramine and other major and expensive medicines used to treat obesity
5.2
16.0
33
65
4111X
ICD-9 Finland
Other acute and subacute forms of ischaemic heart disease, Intermediate coronary syndrome[PITKITTYNYT ANGINA PECTORIS -KOHTAUS,MÄÄRITTELEMÄT]
6.2
16.0
27
44
SPAT1281
SPAT
Other administrative function
2.2
15.9
133
620
212
Kela drug reimbursment
Gout
3.6
15.9
52
147
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
5.4
15.9
31
58
H04AA01
ATC
glucagon; nasal, parenteral
4.6
15.9
38
85
315
Kela drug reimbursment
Clopidogrel
5.8
15.9
29
51
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
15.9
433
2950
UJF32
NOMESCO Finland
Coloscopy
1.6
15.9
436
2976
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.0
15.8
186
989
B04AX03, ,
ATC
60.6
15.8
18
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
15.8
221
1247
C09CA06
ATC
candesartan; oral
1.7
15.7
385
2553
40199
ICD-8 Finland
Essential benign hypertension
4.2
15.7
42
103
H02AB06
ATC
prednisolone; systemic
1.5
15.7
758
5883
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
13.9
15.5
26
19
CKC15
NOMESCO Finland
Panretinal photocoagulation
6.3
15.5
26
42
FNC30
NOMESCO Finland
Aorto-coronary venous bypass with three distal anastomoses
4.4
15.5
38
87
AA1AD
NOMESCO Finland
CT of head and brain
1.6
15.5
469
3276
J01MA12
ATC
levofloxacin; systemic
1.7
15.4
321
2037
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
6.5
15.4
25
39
N03AX12
ATC
[U] gabapentin; oral
1.8
15.4
257
1531
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
15.3
218
1237
A02BC05
ATC
esomeprazole; systemic
1.5
15.2
617
4602
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.5
15.1
53
157
A41.9
ICD-10 Finland
Sepsis, unspecified
2.8
15.1
74
268
A12BA01
ATC
potassium chloride; oral
2.7
15.0
82
314
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
6.3
15.0
25
40
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
4.4
15.0
37
85
111
HP
Conventional CABG
5.8
14.9
27
47
FNE20
NOMESCO Finland
Coronary bypass using free arterial graft of radial artery
6.6
14.9
24
37
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
14.9
665
5055
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.2
14.8
131
625
PD4AD
NOMESCO Finland
CT of lower extremity arteries
6.0
14.8
26
44
I79.2*E11.5
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
16.6
14.8
23
14
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
4.5
14.8
36
82
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
3.7
14.8
46
126
N06AA12
ATC
doxepin; systemic
2.5
14.7
93
383
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.9
14.7
219
1258
R51.80
ICD-10 Finland
Headache
1.9
14.7
215
1228
CK2S4, ,
SPAT
4.0
14.7
42
108
R05FB02
ATC
cough suppressants and expectorants; systemic
1.5
14.7
574
4237
K99
ICPC
Cardiovascular disease other
3.1
14.7
61
201
PD3YT
NOMESCO Finland
Pelvic artery PTA with stent
5.2
14.6
30
59
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
12.0
14.6
26
22
C01BD01
ATC
amiodarone; systemic
3.0
14.6
64
218
E78.1
ICD-10 Finland
Pure hyperglyceridaemia
11.0
14.5
27
25
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.0
14.5
65
224
J01AA02
ATC
doxycycline; systemic
1.6
14.5
1240
10788
H3603, E103,
ICD-10 Finland
12.7
14.4
25
20
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.7
14.4
80
310
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
14.3
142
709
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
14.2
580
4317
C09CA03
ATC
valsartan; oral
2.0
14.2
171
917
CKC12
NOMESCO Finland
Photocoagulation of retina
2.6
14.1
85
342
5315
FHL
Bypass surgery using a mammary artery
4.6
14.0
33
73
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
14.0
167
892
M79.6
ICD-10 Finland
Pain in limb
1.5
13.9
656
5025
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
13.9
174
945
R11
ICD-10 Finland
Nausea and vomiting
2.2
13.8
125
602
Z71.8
ICD-10 Finland
Other specified counselling
1.6
13.8
469
3348
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
13.7
1090
9264
BEF00, ,
SPAT
5.8
13.7
25
44
E78
ICD-10 Finland
Disorders of lipoprotein metabolism and other lipidaemias
3.0
13.7
59
199
AN3
HP
Balloon angioplasty and metallic stent
3.2
13.6
54
173
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.3
13.6
51
158
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
12.2
13.6
24
20
M54.5
ICD-10 Finland
Low back pain
1.5
13.6
533
3926
A02BC03
ATC
lansoprazole; oral
1.6
13.5
446
3161
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.3
13.5
102
456
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
13.5
135
676
C10AD06
ATC
acipimox; oral
141.1
13.5
14
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.1
13.3
123
597
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
21.3
13.3
19
9
R80
ICD-10 Finland
Isolated proteinuria
6.4
13.3
22
35
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
6.4
13.3
22
35
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
13.3
383
2630
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
5.4
13.3
26
49
R03AC02
ATC
salbutamol; inhalant
1.5
13.3
805
6468
A02BC01
ATC
omeprazole; systemic
1.6
13.2
411
2871
A10BX09
ATC
[U] dapagliflozin
5.8
13.2
24
42
R4110
NOMESCO Finland
Physiotherapy
1.6
13.2
408
2846
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
4.0
13.2
37
94
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
13.2
217
1284
M01AB01
ATC
indometacin; systemic, rectal
2.0
13.0
148
778
A06AD11
ATC
lactulose; oral
1.7
12.9
247
1526
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
2.4
12.9
85
358
B01AB05
ATC
enoxaparin; parenteral
1.5
12.8
481
3499
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
11.6
12.8
23
20
R55
ICD-10 Finland
Syncope and collapse
1.9
12.8
179
1008
E83.50
ICD-10 Finland
Hypercalcemia
10.6
12.8
24
23
3472A
ICD-9 Finland
Cataplexy and narcolepsy[OBSTRUKTIIVINEN UNIAPNEA]
4.0
12.7
36
92
I25.8
ICD-10 Finland
Other forms of chronic ischaemic heart disease
4.2
12.7
33
79
B01AF02
ATC
apixaban; oral
1.7
12.7
235
1439
P29
ICPC
Psychological sympt/compl other
2.3
12.6
97
437
Z02.7
ICD-10 Finland
Issue of medical certificate
2.1
12.6
121
597
C02CA01
ATC
prazosin; oral
3.8
12.6
38
102
E83.51
ICD-10 Finland
Hypocalcemia
32.3
12.6
16
5
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
12.5
106
497
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
12.5
217
1304
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.5
12.4
75
303
C02DE04, ,
ATC
3.3
12.4
47
147
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.3
12.4
45
137
P03
ICPC
Feeling depressed
2.1
12.4
117
574
C09DA01
ATC
losartan and diuretics; oral
1.8
12.3
187
1081
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
9.0
12.2
25
28
P01AB01
ATC
metronidazole; oral, rectal
1.5
12.2
556
4202
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
3.1
12.1
49
159
C07AA07
ATC
sotalol; systemic
2.6
12.1
69
271
104
Kela drug reimbursment
Thyroid insufficiency
2.3
12.1
96
439
E0000UV, ,
ATC
1.5
12.1
603
4640
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
9.3
12.0
24
26
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.2
12.0
99
460
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
5.1
12.0
25
50
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
11.9
1008
8550
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.7
11.9
62
232
XF602
NOMESCO Finland
Bloodpressure monitoring
4.9
11.9
26
54
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.6
11.9
38
106
F32
ICD-10 Finland
Depressive episode
2.6
11.9
70
279
C10AC01
ATC
colestyramine; oral
3.1
11.9
49
161
H25.8
ICD-10 Finland
Other senile cataract
1.8
11.9
198
1175
E66
ICD-10 Finland
Obesity
2.4
11.8
79
335
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
10.6
11.8
22
21
M03BX02
ATC
tizanidine; oral
1.4
11.7
912
7607
B01AC24
ATC
ticagrelor; oral
2.5
11.7
72
293
N30.0
ICD-10 Finland
Acute cystitis
1.7
11.7
208
1257
N17.8
ICD-10 Finland
Other acute renal failure
4.4
11.7
29
67
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.7
11.7
64
246
Z94.0
ICD-10 Finland
Kidney transplant status
5.0
11.7
25
51
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.5
11.7
76
318
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
3.9
11.7
34
89
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.1
11.7
116
580
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
2.8
11.6
57
207
I44.2
ICD-10 Finland
Atrioventricular block, complete
2.7
11.6
60
224
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.1
11.6
115
574
N05BA12
ATC
alprazolam; oral
1.9
11.6
155
859
R06AE07
ATC
cetirizine; oral
1.5
11.6
589
4538
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
23.1
11.6
16
7
C09AA01
ATC
captopril; oral
3.3
11.5
42
128
C01AA05
ATC
digoxin; systemic
1.9
11.5
144
781
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.7
11.5
21
37
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
11.4
380
2685
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
4.2
11.3
30
73
127
Kela drug reimbursment
Transplant complication
4.2
11.3
30
73
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
2.7
11.3
61
233
R05FA02
ATC
opium derivatives and expectorants; systemic
1.5
11.3
574
4418
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
11.3
253
1628
K02.1
ICD-10 Finland
Caries of dentine
1.4
11.2
850
7033
207
Kela drug reimbursment
Chronic arrhythmias
1.6
11.2
276
1817
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
11.2
163
928
A10BD08
ATC
metformin and vildagliptin; systemic
4.8
11.2
25
53
137
Kela drug reimbursment
Uraemia requiring dialysis
5.6
11.2
21
38
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.0
11.0
48
163
T92
ICPC
Gout
2.9
11.0
50
174
N03AX09
ATC
lamotrigine; oral
2.5
11.0
67
272
M48.0
ICD-10 Finland
Spinal stenosis
1.7
11.0
210
1296
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
10.9
160
913
A01
ICPC
Pain general/multiple sites
1.9
10.9
148
824
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
10.9
111
560
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
10.9
530
4042
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
4.3
10.8
27
63
SPAT1260
SPAT
Consultation of another employee
1.6
10.7
260
1704
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
10.7
416
3030
SPAT1097
SPAT
Recording of ECG
1.7
10.7
227
1439
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
10.7
211
1312
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
10.7
633
4999
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.0
10.7
120
627
SPAT1229
SPAT
Assessment of need for aid
2.0
10.7
124
656
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.9
10.7
130
699
S21
ICPC
Skin texture symptom/complaint
1.7
10.6
234
1497
J01CF05
ATC
flucloxacillin; systemic
2.0
10.6
114
586
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
5.3
10.6
21
40
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
10.6
660
5258
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
10.6
383
2750
A10BH02
ATC
vildagliptin; oral
3.3
10.6
39
120
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.6
10.5
60
236
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.5
10.5
25
56
SPAT1054
SPAT
Examination of peripheral nervous system
3.5
10.5
35
101
N02BF02
ATC
pregabalin; oral
2.1
10.4
102
507
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
10.4
486
3670
K05.31
ICD-10 Finland
Periodontitis pronounced
1.7
10.4
189
1150
PD3AT
NOMESCO Finland
Pelvic artery PTA
12.1
10.3
18
15
Z50.0
ICD-10 Finland
Cardiac rehabilitation
4.3
10.3
26
61
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
4.4
10.3
25
57
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.6
10.3
59
233
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
4.7
10.2
23
49
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.1
10.1
99
492
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.6
10.1
56
217
C07AB05
ATC
betaxolol; oral
2.9
10.1
47
166
J01FA06
ATC
roxithromycin; oral
1.4
10.1
577
4517
R4190
NOMESCO Finland
Nutritional therapy
2.5
10.1
63
259
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.9
10.1
136
756
196
Kela drug reimbursment
Paricalcitol and cinacalcet
8.5
10.0
21
25
C09DA07
ATC
telmisartan and diuretics; oral
2.4
10.0
71
309
D11
ICPC
Diarrhoea
1.8
10.0
157
914
K74
ICPC
Ischaemic heart dis with angina
4.5
10.0
24
54
QBJ30
NOMESCO Finland
Correction of abdominal apron
14.7
10.0
16
11
H02AB04
ATC
methylprednisolone; systemic
1.7
10.0
214
1359
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.5
9.9
63
261
E29.1
ICD-10 Finland
Testicular hypofunction
3.5
9.9
33
95
WX722
NOMESCO Finland
PEEP
2.2
9.9
87
415
EB1AA, ,
SPAT
2.1
9.9
91
442
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
16.8
9.9
15
9
ZX120
NOMESCO Finland
Intravenous
1.8
9.9
138
776
SPAT1255
SPAT
Intravenous administration of medicine
2.0
9.8
109
568
SFA10
NOMESCO Finland
One-surface restoration
1.4
9.8
793
6580
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.0
9.8
108
561
A10BX02
ATC
repaglinide; oral
3.8
9.8
29
77
3025
Kela drug reimbursment
Calcium carbonate
10.7
9.8
18
17
R60.0
ICD-10 Finland
Localized oedema
1.7
9.8
197
1232
Z2221
NOMESCO Finland
Medical doctor
1.5
9.7
364
2626
D29
ICPC
Digestive symptom/complaint other
3.0
9.7
41
137
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
3.7
9.7
30
82
N06AB06
ATC
sertraline; oral
1.8
9.7
147
847
ZXA00
NOMESCO Finland
Right side
1.5
9.7
394
2889
K92.1
ICD-10 Finland
Melaena
2.1
9.7
92
452
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
9.7
362
2610
C09AA03
ATC
lisinopril; oral
2.2
9.7
80
372
SFA20
NOMESCO Finland
Two-surface restoration
1.4
9.7
839
7037
321
Kela drug reimbursment
Paricalcitol and cinacalcet
5.3
9.6
19
36
Z50.1
ICD-10 Finland
Other physical therapy
2.1
9.6
86
413
J01DA09
ATC
[U] cefadroxil
1.5
9.6
374
2721
SPAT1254
SPAT
Administration of medicine
1.6
9.6
216
1390
M01AH02
ATC
rofecoxib; oral
1.7
9.5
195
1223
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
9.5
218
1407
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.8
9.5
137
777
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
9.5
268
1819
A10BD20
ATC
metformin and empagliflozin; oral
3.5
9.5
32
93
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.2
9.5
36
113
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.2
9.5
36
113
L04AA06
ATC
mycophenolic acid; systemic
3.3
9.5
34
103
J01MA01
ATC
ofloxacin; systemic
1.8
9.4
136
772
A11
ICPC
Chest pain NOS
1.8
9.4
133
750
E87.2
ICD-10 Finland
Acidosis
100.6
9.4
10
*
R52.9
ICD-10 Finland
Pain, unspecified
1.8
9.4
150
878
AP1
HP
Catheterization of the left side of the heart
3.6
9.4
30
84
A99
ICPC
Disease/condition unspecnature/site
1.7
9.4
162
970
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.0
9.4
41
140
A08AB01
ATC
orlistat; oral
5.2
9.4
19
37
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
9.4
165
994
F60.9
ICD-10 Finland
Personality disorder, unspecified
4.4
9.3
23
53
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
3.8
9.3
28
75
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
9.3
291
2020
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
8.7
9.3
19
22
R31
ICD-10 Finland
Unspecified haematuria
1.7
9.3
184
1145
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.8
9.3
147
859
C09DA06
ATC
candesartan and diuretics; oral
1.9
9.3
122
673
EBA30
NOMESCO Finland
Extraction of root of tooth
2.0
9.3
107
565
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.0
9.3
104
544
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.3
256
1729
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.3
749
6195
XCH00
NOMESCO Finland
Eye pressure measurement
2.1
9.2
85
413
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
9.2
318
2253
J01CA04
ATC
amoxicillin; systemic
1.4
9.2
1227
11010
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.8
9.2
46
169
CL2S4, ,
SPAT
2.8
9.2
44
158
PEN23
NOMESCO Finland
Plastic repair of femoral artery
5.0
9.1
19
38
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
3.8
9.1
27
72
ACC51
NOMESCO Finland
Release of median nerve
1.9
9.1
115
627
M79.1
ICD-10 Finland
Myalgia
1.6
9.0
197
1256
N02AA05
ATC
oxycodone; systemic
1.5
9.0
302
2126
F61.0
ICD-10 Finland
Mixed personality disorders
3.7
9.0
28
77
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.2
9.0
72
331
A04
ICPC
Weakness/tiredness general
1.6
8.9
212
1380
N05AX12
ATC
aripiprazole; systemic
2.5
8.9
53
213
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
8.9
796
6673
C09CA07
ATC
telmisartan; oral
1.9
8.9
121
674
41300
ICD-8 Finland
Angina pectoris, Cum hypertonia
24.1
8.9
12
5
PFP26
NOMESCO Finland
Percutaneous plastic repair of popliteal artery
24.1
8.9
12
5
A97
ICPC
No disease
1.5
8.9
289
2021
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
8.9
183
1150
K81.9
ICD-10 Finland
Cholecystitis, unspecified
4.0
8.9
25
64
5313
FHL
Bypass surgery for three vessels
8.0
8.9
19
24
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.5
8.8
53
214
A10AA03, ,
ATC
4.9
8.8
19
39
PEH57
NOMESCO Finland
Bypass from femoral artery to popliteal artery below knee
4.9
8.8
19
39
B03XA02
ATC
darbepoetin alfa; parenteral
2.9
8.8
41
145
XCK00
NOMESCO Finland
Perimetry
2.0
8.8
93
476
R06.2
ICD-10 Finland
Wheezing
2.2
8.8
70
321
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
8.7
8.8
18
21
S18
ICPC
Laceration/cut
1.4
8.8
741
6152
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
8.8
296
2086
R03BB04
ATC
tiotropium bromide; inhalant
1.7
8.8
168
1035
M01AE02
ATC
naproxen; oral, rectal
1.4
8.8
801
6733
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
9.5
8.8
17
18
R52.2
ICD-10 Finland
Other chronic pain
2.4
8.7
59
252
4140X
ICD-9 Finland
Other forms of chronic ischaemic heart disease, Coronary atherosclerosis[ATHEROSCLEROSIS ARTER CORON CORDIS,MÄÄRITTELEMÄT]
7.2
8.7
20
28
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
8.7
252
1718
FL1AC
NOMESCO Finland
Left cardioangiography
3.2
8.7
34
109
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
8.7
105
564
N05CF02
ATC
zolpidem; oral
1.6
8.7
237
1596
PH2CD
NOMESCO Finland
Very extensive CT of inferior vena cava, pelvic veins and veins of lower extremity
7.7
8.6
19
25
U14
ICPC
Kidney symptom/complaint
3.3
8.6
32
99
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
2.6
8.6
48
187
L04AD02
ATC
tacrolimus; systemic
4.8
8.6
19
40
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.2
8.6
69
318
4110X
ICD-9 Finland
Other acute and subacute forms of ischaemic heart disease, Postmyocardial infarction syndrome[EPÄSTABIILI ANGINA PECTORIS,MÄÄRITTELEMÄT]
8.3
8.6
18
22
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
8.6
469
3624
H05BX01
ATC
cinacalcet; oral
6.4
8.5
21
33
B04AC01, ,
ATC
20.1
8.5
12
6
-50
ICPC
Medication/prescr/renewal
2.3
8.5
65
294
C08CA10
ATC
nilvadipine; oral
3.1
8.5
35
116
N17
ICPC
Vertigo/dizziness
1.6
8.4
181
1149
E78.3
ICD-10 Finland
Hyperchylomicronaemia
90.5
8.4
9
*
M02AA07
ATC
piroxicam; topical
1.4
8.4
532
4211
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.5
8.4
28
81
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
8.4
323
2338
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
8.4
146
877
N06AX26
ATC
vortioxetine; oral
2.0
8.4
90
464
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
4.9
8.4
18
37
PE1BT
NOMESCO Finland
Femoral artery extensive PTA
4.9
8.4
18
37
T93
ICPC
Lipid disorder
1.8
8.4
118
666
SPAT1240
SPAT
Therapeutic discussion
1.8
8.4
118
666
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
+∞
8.3
8
*
I79.2
ICD-10 Finland
Peripheral angiopathy in diseases classified elsewhere
+∞
8.3
8
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
8.3
129
749
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
10.8
8.3
15
14
TK810
NOMESCO Finland
Hemofiltration
9.5
8.3
16
17
WX872
NOMESCO Finland
Intensive care
2.1
8.3
81
404
TQW11
NOMESCO Finland
Vacuum treatment of wound
2.9
8.2
38
134
WX892
NOMESCO Finland
Monitored bed care
1.8
8.2
113
632
K76.9
ICD-10 Finland
Liver disease, unspecified
3.5
8.2
28
82
J01EA01
ATC
trimethoprim; systemic
1.5
8.2
316
2286
R06.5
ICD-10 Finland
Mouth breathing
1.7
8.2
143
859
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.2
8.2
67
311
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
8.2
370
2759
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
2.7
8.2
43
163
Z3229
NOMESCO Finland
Other healthcare associate professional
1.8
8.2
128
746
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.9
8.1
38
135
N06AB03
ATC
fluoxetine; oral
1.7
8.1
166
1041
K78
ICPC
Atrial fibrillation/flutter
1.8
8.1
128
748
PC5DE
NOMESCO Finland
Ultrasound of kidney circulation with Doppler technic
8.2
8.1
17
21
R03BA05
ATC
fluticasone; inhalant
1.5
8.1
242
1663
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.5
8.0
49
200
XA420
NOMESCO Finland
Extensive sleep examination
3.9
8.0
23
60
5253
FHL
Cardiac lung machine
3.9
8.0
23
60
K08.3
ICD-10 Finland
Retained dental root
1.8
8.0
129
759
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.7
8.0
40
148
D01
ICPC
Abdominal pain/cramps general
1.7
7.9
152
937
I21.90
ICD-10 Finland
Myocardial infarction (acute) UNS no detected stenosis of the coronary artery
3.0
7.9
33
110
N06AX05
ATC
trazodone; oral
2.8
7.9
39
143
ZXA10
NOMESCO Finland
Bilateral
1.5
7.9
260
1822
JDF01
NOMESCO Finland
Laparoscopic gastroplasty
13.1
7.9
13
10
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
7.8
7.9
17
22
N02AC04
ATC
dextropropoxyphene; oral
2.3
7.9
60
271
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
7.8
337
2488
A29
ICPC
General symptom/complaint other
1.6
7.8
198
1308
WX110, ,
SPAT
2.1
7.8
74
364
L03
ICPC
Low back symptom/complaint
1.4
7.8
386
2922
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.5
7.8
49
203
Z72.0
ICD-10 Finland
Tobacco use
2.7
7.7
41
156
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.7
7.7
41
156
FN2CC
NOMESCO Finland
Percutaneous transluminal coronary angioplasty (PTCA) of left main trunk
4.2
7.7
20
48
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.7
356
2661
SGA01
NOMESCO Finland
Emergency treatment
1.5
7.7
219
1485
WX199
NOMESCO Finland
Other local analgesia
2.2
7.7
60
273
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.6
7.7
42
162
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
7.7
152
944
S76
ICPC
Skin infection other
1.9
7.7
88
464
R4180
NOMESCO Finland
Podiatric therapy
3.5
7.7
26
76
C08CA03
ATC
isradipine; systemic
3.5
7.7
26
76
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.7
266
1883
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
7.7
415
3191
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.4
7.6
50
211
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.6
247
1724
SPAT1251
SPAT
Organisation of medication
2.3
7.6
53
230
XF640, ,
NOMESCO Finland
2.6
7.6
44
175
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.0
7.6
77
389
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.7
7.6
18
27
PEP25
NOMESCO Finland
Percutaneous plastic repair of superficial femoral artery
11.9
7.6
13
11
S10
ICPC
Boil/carbuncle
1.9
7.6
90
481
SPAT1211
SPAT
Application of soft bandage
1.7
7.5
125
741
M01AX17
ATC
nimesulide; oral
1.4
7.5
355
2666
J20
ICD-10 Finland
Acute bronchitis
1.7
7.5
138
842
SPAT1312
SPAT
General health counselling
1.4
7.5
428
3320
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.1
7.5
68
330
SPAT1252
SPAT
Overall medication plan or its review
1.8
7.5
104
585
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
2.2
7.5
63
297
K85
ICD-10 Finland
Acute pancreatitis
2.9
7.5
33
114
XCD20
NOMESCO Finland
Photoangiography of eye
3.1
7.4
30
98
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.7
7.4
142
875
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
7.4
197
1316
SPAT1070
SPAT
Doppler ultrasound examination of blood flow in arteries of lower extremity
2.9
7.4
34
120
N30.9
ICD-10 Finland
Cystitis, unspecified
2.0
7.4
81
421
B03BA03
ATC
hydroxocobalamin; parenteral
1.9
7.4
90
485
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.4
7.4
392
3002
A02BA03
ATC
famotidine; systemic
2.2
7.4
61
285
K29
ICPC
Cardiovascular sympt/complt other
2.1
7.4
71
352
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.2
7.4
57
259
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
2.5
7.4
43
172
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
7.3
98
544
B82
ICPC
Anaemia other/unspecified
2.3
7.3
53
234
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.3
266
1900
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
7.3
218
1495
N0830, E112,
ICD-10 Finland
+∞
7.3
7
*
2724X
ICD-9 Finland
Disorders of lipoid metabolism, Other and unspecified hyperlipidaemia[HYPERLIPOIDAEMIA ALIA]
+∞
7.3
7
*
V03AE02
ATC
sevelamer; oral
6.9
7.3
17
25
2780A
ICD-9 Finland
Obesity and other hyperalimentation, Obesity
6.9
7.3
17
25
2500X
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,NUD]
9.4
7.3
14
15
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
7.3
282
2040
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.9
7.3
90
488
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.4
7.3
49
210
C09AA04
ATC
perindopril; oral
2.0
7.2
78
403
B81
ICPC
Anaemia vit B12/folate deficiency
2.2
7.2
62
294
H3602, E113,
ICD-10 Finland
15.8
7.2
11
7
N06AX03
ATC
mianserin; oral
2.0
7.2
73
369
4740A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Chronic tonsillitis
2.8
7.2
34
122
N07BB01
ATC
disulfiram; oral
2.1
7.2
69
342
S17
ICPC
Abrasion/scratch/blister
2.7
7.2
37
139
I21.10
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
4.0
7.2
20
51
UKC02
NOMESCO Finland
Cystoscopy
1.5
7.2
266
1908
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
7.2
88
476
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
20.1
7.1
10
5
R05DB05
ATC
pentoxyverine; oral, rectal
2.3
7.1
53
237
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
7.1
236
1654
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
3.3
7.1
26
80
I70.0
ICD-10 Finland
Atherosclerosis of aorta
6.6
7.1
17
26
TKC20
NOMESCO Finland
Catheterisation of bladder
1.8
7.1
105
602
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
3.0
7.1
30
101
FNC40
NOMESCO Finland
Aorto-coronary venous bypass with four distal anastomoses
4.1
7.1
19
47
M14.6*E11.6
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic neuropathic
12.1
7.1
12
10
WZC30
NOMESCO Finland
Teaching
1.5
7.1
251
1784
S06.0
ICD-10 Finland
Concussion
1.6
7.0
149
943
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.0
595
4896
C10AA06
ATC
cerivastatin; oral
10.1
7.0
13
13
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.9
7.0
89
486
I21.00
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
3.1
7.0
28
91
N05AX08
ATC
risperidone; systemic
1.7
7.0
128
779
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.4
7.0
48
207
ZXD20
NOMESCO Finland
Day surgery
1.6
7.0
167
1089
WX290
NOMESCO Finland
Other blockage of nerve
1.3
7.0
623
5165
FN2CA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty (PTCA), treating more than one main trunk during a single procedure
3.3
7.0
25
76
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.7
6.9
112
659
Z49.2
ICD-10 Finland
Other dialysis
5.5
6.9
19
35
NGQ20
NOMESCO Finland
Amputation of lower leg
5.9
6.9
18
31
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
6.9
104
600
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
1.8
6.9
104
600
R4120
NOMESCO Finland
Occupational therapy
1.9
6.9
86
468
C09BA03
ATC
lisinopril and diuretics; oral
2.5
6.9
40
160
E000003, ,
ATC
2.2
6.9
55
254
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
6.9
149
949
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
6.8
133
824
SPAT1325
SPAT
Vaccination
1.4
6.8
474
3785
SPAT1310
SPAT
Counselling related to known health issue
1.4
6.8
437
3448
ANC
HP
Coronary artery pressure measurement (FFR, fractional flow reserve)
6.1
6.8
17
28
B05DB
ATC
Hypertonic solutions
6.1
6.8
17
28
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.8
415
3249
B04AD02, ,
ATC
40.2
6.8
8
*
NFQ20
NOMESCO Finland
Amputation of femur
4.3
6.8
17
40
27901
ICD-8 Finland
Other and unspecified metabolic diseases, Hyperlipaemia, hyperglyceridaemia non familiaris NUD
16.8
6.7
10
6
S09
ICPC
Infected finger/toe
2.3
6.7
51
230
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.6
6.7
113
1822
D07AC01
ATC
betamethasone; topical
1.3
6.7
529
4301
D19
ICPC
Teeth/gum symptom/complaint
1.4
6.7
409
3198
PEF25
NOMESCO Finland
Thrombendarterectomy of superficial femoral artery
7.2
6.7
15
21
I20.9
ICD-10 Finland
Angina pectoris, unspecified
3.3
6.7
24
73
S29
ICPC
Skin symptom/complaint other
1.4
6.7
286
2105
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
6.7
88
487
K29.7
ICD-10 Finland
Gastritis, unspecified
2.2
6.7
56
264
D02AE01
ATC
carbamide; topical
1.8
6.7
89
495
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
6.5
6.6
16
25
FN2CB
NOMESCO Finland
Percutaneous transluminal coronary angioplasty (PTCA) of coronary chronic total occlusion
6.5
6.6
16
25
FN1XT
NOMESCO Finland
Other coronary artery procedure through catheter
6.5
6.6
16
25
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.1
6.6
57
271
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.1
6.6
27
89
I95.1
ICD-10 Finland
Orthostatic hypotension
2.1
6.6
61
298
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.0
6.6
69
353
SPAT1283
SPAT
Restricted health certificate
1.6
6.6
150
966
L86
ICPC
Back syndrome with radiating pain
1.8
6.6
90
504
A41.8
ICD-10 Finland
Other specified sepsis
2.6
6.6
35
134
SFA30
NOMESCO Finland
Three-surface restoration
1.3
6.6
622
5189
I21.4
ICD-10 Finland
Acute subendocardial myocardial infarction
3.3
6.6
24
74
D07AB08
ATC
desonide; topical
1.6
6.6
147
944
A10AD04
ATC
insulin lispro; parenteral
8.7
6.6
13
15
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.0
6.5
65
327
Z01.9
ICD-10 Finland
Special examination, unspecified
1.8
6.5
91
513
U07
ICPC
Urine symptom/complaint other
1.7
6.5
119
725
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.4
6.5
44
189
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
6.5
156
1018
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.4
6.5
43
183
N05AB03
ATC
perphenazine; systemic, rectal
2.2
6.5
51
234
R4180, ,
SPAT
3.1
6.5
26
85
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
2.4
6.5
41
171
WX213
NOMESCO Finland
Lower leg blockade
5.3
6.5
18
34
K85
ICPC
Elevated blood pressure
1.5
6.5
247
1780
BC1AD
NOMESCO Finland
CT of adrenal glands
3.5
6.4
21
60
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
3.9
6.4
18
46
R05
ICD-10 Finland
Cough
1.4
6.4
287
2128
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
3.2
6.4
24
75
ZXA05
NOMESCO Finland
Left side
1.4
6.4
343
2623
C09DX04
ATC
valsartan and sacubitril; oral
3.4
6.4
22
65
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
2.2
6.4
49
222
J01FA01
ATC
erythromycin; systemic
1.6
6.4
151
981
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
1.9
6.4
72
378
V03AE03
ATC
lanthanum carbonate; oral
7.4
6.4
14
19
7865A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Chest pain
2.8
6.4
31
113
A02BX02
ATC
sucralfate; oral
2.1
6.4
58
282
S20
ICPC
Corn/callosity
2.6
6.4
36
142
K77
ICPC
Heart failure
2.6
6.4
36
142
WW200, ,
SPAT
0.7
6.4
288
3786
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.4
1014
9055
64090
ICD-8 Finland
Artificial termination of pregnancy performed for medical reasons, Woman's illness or physical defect (medicines. Cause)
4.1
6.4
17
42
I20.8
ICD-10 Finland
Other forms of angina pectoris
4.1
6.4
17
42
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
8.2
6.3
13
16
SPAT1216
SPAT
Assessment of functional ability
1.5
6.3
227
1616
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.6
6.3
148
961
E26.0
ICD-10 Finland
Primary hyperaldosteronism
6.0
6.3
16
27
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
6.3
212
1490
R39.1
ICD-10 Finland
Other difficulties with micturition
2.2
6.3
51
237
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
3.5
6.3
21
61
A08
ICPC
Swelling
1.8
6.3
83
460
H3601, E106,
ICD-10 Finland
+∞
6.3
6
*
R26.2
ICD-10 Finland
Difficulty in walking, not elsewhere classified
3.0
6.2
26
87
C07FB02
ATC
metoprolol and felodipine; systemic
2.2
6.2
49
225
H3601, E116,
ICD-10 Finland
26.8
6.2
8
*
M10.3
ICD-10 Finland
Gout due to impairment of renal function
7.0
6.2
14
20
FM1TQ
NOMESCO Finland
Heart perfusion SPECT with low dose CT at rest and with exercise
7.0
6.2
14
20
N06AX12
ATC
bupropion; oral
1.9
6.2
76
411
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
2.3
6.2
43
187
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.9
6.2
76
412
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.2
6.2
23
72
SPAT1172
SPAT
Guidance concerning hydration
2.6
6.1
33
127
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
2.6
6.1
33
127
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
5.8
6.1
16
28
7804A
ICD-9 Finland
General symptoms, Dizziness and giddiness
3.3
6.1
22
67
N20.0
ICD-10 Finland
Calculus of kidney
2.5
6.1
36
145
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.1
514
4209
D01AC02
ATC
miconazole; topical
1.7
6.1
115
707
C09DA03
ATC
valsartan and diuretics; oral
1.9
6.1
72
385
Z13.5
ICD-10 Finland
Special screening examination for eye and ear disorders
4.1
6.1
16
39
T83
ICPC
Overweight
2.9
6.1
27
94
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
6.7
6.0
14
21
E11.09
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - With coma
10.1
6.0
11
11
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.1
6.0
11
11
D07XC01
ATC
betamethasone; topical
1.5
6.0
183
1259
P01
ICPC
Feeling anxious/nervous/tense
1.7
6.0
104
625
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.4
6.0
21
63

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1016
4907
3.73
150.38
6.2
3.9
19.21
6.24
mg/mmol
6.66
756
3046
997
4808
3.66
146.81
5.0
3.3
93.37
35.76
mg/l
8.26
762
3079
1003
4997
3.52
137.22
5.2
3.3
7.28
7.96
mmol/l
5.35
887
4134
358
1268
3.32
79.31
12.1
6.3
12.42
9.96
mmol/l
5.99
344
1212
145
260
6.01
78.29
1.6
1.7
1.02
0.84
nmol/l
1.34
122
220
431
1744
2.98
75.59
10.7
5.3
1.11
1.01
mmol/l
8.24
410
1610
801
4519
2.48
71.10
4.2
3.0
2624.33
1319.10
ng/l
4.32
706
3879
762
4315
2.41
65.64
3.1
2.1
270.32
249.89
u/l
0.15
723
4087
142
312
4.88
60.93
2.5
2.2
193.62
117.43
ug/min
0.64
93
183
354
1444
2.84
59.81
5.4
3.3
7.37
7.38
ph
3.78
242
814
681
3792
2.34
59.52
3.7
2.7
383.95
351.08
umol/l
10.41
601
3299
343
1398
2.83
57.88
5.5
3.2
1.49
1.93
mmol/l
1.18
299
1226
481
2351
2.47
55.85
4.0
2.4
11.70
13.20
umol/l
4.45
451
2202
1022
6861
2.26
55.49
21.9
15.7
1.35
1.29
inr
2.20
870
5737
455
2182
2.49
54.94
3.9
2.4
2.35
2.28
g/l
1.99
426
2020
345
1448
2.74
54.78
5.4
3.2
5.91
5.83
kpa
0.72
330
1412
1178
8413
2.35
54.72
9.4
4.7
7.87
6.73
mmol/l
34.67
1143
8018
432
2040
2.51
53.79
4.0
2.4
19.80
23.44
%
7.69
410
1904
957
6355
2.18
52.04
6.7
4.9
35.08
35.40
g/l
0.97
901
5906
740
4487
2.16
50.33
3.3
3.1
34.25
37.44
u/l
0.68
689
4209
636
3640
2.21
50.02
3.0
2.2
3.23
2.94
mg/l
2.38
562
3113
297
1248
2.68
46.47
4.1
2.5
4.79
4.53
kpa
0.97
279
1219
242
924
2.89
45.43
5.1
3.5
127.79
89.89
ng/l
3.85
208
792
848
5565
2.06
45.25
6.1
3.5
126.94
60.34
ng/l
0.39
680
4169
1014
7126
2.07
44.55
12.4
6.6
1.20
1.21
mmol/l
1.62
877
6084
80
144
5.78
42.77
1.4
1.2
1.69
1.49
nmol/l
0.65
74
131
230
890
2.84
41.96
4.7
3.5
7.41
7.42
ph
1.93
193
745
234
919
2.80
41.49
4.8
3.5
5.05
5.16
kpa
1.32
227
890
1039
7486
2.02
41.10
6.8
6.7
11.35
12.13
umol/l
1.54
987
7150
91
193
4.93
40.54
1.2
1.1
101.52
116.49
iu/ml
0.05
21
38
355
1723
2.35
40.31
3.5
2.6
1.88
1.75
%
2.08
322
1552
432
2279
2.21
40.15
3.9
3.3
0.81
0.82
mmol/l
1.15
407
2156
78
151
5.37
38.55
2.9
2.4
1.92
1.69
g/24h
0.17
52
83
257
1103
2.57
38.04
2.0
2.3
366.77
369.73
nmol/l
0.08
225
1032
277
1234
2.49
37.89
3.0
2.2
7.31
7.90
ug/l
0.16
247
1104
273
1213
2.49
37.53
12.8
8.6
—
—
—
0
0
652
4158
1.93
35.14
6.0
4.3
—
—
—
0
0
691
4503
1.91
34.79
2.8
2.5
—
—
—
0
0
901
6400
1.88
34.64
2.6
2.1
94.62
95.02
pmol/l
0.10
551
3486
171
641
2.86
32.83
4.8
3.7
—
—
—
0
0
765
5236
1.85
32.33
5.8
3.7
73.73
110.97
e6/l
1.11
575
3815
169
651
2.78
30.77
1.6
1.9
1.78
1.49
g/l
3.18
149
568
700
4728
1.83
30.31
5.2
3.2
52.18
99.86
e6/l
1.33
566
3662
835
5955
1.80
30.10
4.4
2.8
166.94
156.63
ug/l
0.41
769
5473
486
2933
1.93
29.96
1.8
1.6
1.09
1.42
mg/l
2.22
370
2271
313
1634
2.13
28.86
2.2
1.7
—
—
—
0
0
134
478
2.96
28.07
2.2
3.7
45.44
44.71
mg/l
0.03
118
411
134
479
2.95
27.97
2.2
3.7
65.15
57.77
mg/l
0.15
118
408
256
1253
2.23
27.70
1.9
2.6
66.47
66.59
g/l
0.08
235
1146
1318
10938
1.97
27.68
10.6
8.1
84.24
79.27
u/l
2.19
1264
10352
708
4903
1.77
27.40
3.7
3.5
2.36
2.35
mmol/l
0.54
653
4413
373
2113
1.98
27.37
2.2
1.9
30.40
29.83
s
0.66
367
2050
123
426
3.04
27.14
2.1
3.4
2.95
3.36
ratio
0.09
73
244
539
3456
1.83
26.96
2.7
2.4
—
—
—
0
0
521
3312
1.83
26.77
4.3
2.5
4.75
4.66
e6/l
0.06
493
3013
423
2523
1.91
26.54
2.0
1.7
1124.02
1161.19
nmol/l
0.34
334
1928
869
6417
1.74
26.50
11.9
6.0
1.21
1.21
mmol/l
0.21
814
5879
362
2051
1.98
26.45
2.8
2.0
—
—
—
0
0
954
7241
1.74
26.26
7.4
6.3
1.92
1.92
e9/l
0.02
835
6370
258
1295
2.17
26.13
11.4
7.3
1.50
1.37
mmol/l
0.96
252
1274
821
5984
1.73
26.10
3.2
2.3
72.62
78.41
nmol/l
7.23
749
5285
186
823
2.42
25.35
5.5
3.4
23.84
24.31
mmol/l
1.06
178
814
868
6462
1.71
25.23
6.9
6.4
59.39
57.68
%
4.31
832
6163
656
4532
1.74
24.96
3.2
2.5
53.76
62.86
u/l
3.68
613
4170
615
4176
1.75
24.87
7.8
3.9
7.39
7.40
ph
0.89
473
3043
933
7104
1.71
24.77
7.3
6.2
0.04
0.04
e9/l
1.48
807
6087
743
5325
1.71
24.65
5.1
3.4
—
0.77
—
0
22
260
1346
2.10
24.21
3.5
2.8
76.99
67.71
e9/l
4.32
204
1007
928
7084
1.70
24.15
7.2
6.2
0.64
0.60
e9/l
4.15
802
6074
877
6603
1.69
23.96
7.3
6.5
25.81
27.06
%
2.71
839
6236
280
1498
2.04
23.84
11.1
8.2
93.93
95.52
%
2.53
275
1447
793
5833
1.68
23.51
4.8
3.3
6.22
6.21
ph
0.14
458
3276
610
4183
1.72
23.49
1.9
1.7
20.70
19.94
nmol/l
0.32
527
3483
472
3028
1.78
22.89
2.1
1.8
21995288.39
33547268.82
pmol/l
0.19
391
2498
946
7318
1.67
22.87
7.7
6.5
0.21
0.20
e9/l
1.38
822
6372
114
419
2.85
22.58
3.8
2.6
2.01
1.56
mg/l
3.84
108
376
57
135
4.34
22.18
2.5
2.4
—
—
—
0
0
210
1035
2.18
22.09
1.8
2.4
—
—
—
0
0
856
6489
1.65
22.09
7.2
6.6
8.83
9.10
%
2.09
805
6058
852
6479
1.64
21.49
7.3
6.6
0.67
0.68
%
0.12
797
6037
57
140
4.18
21.16
20.6
4.6
8.81
6.74
mmol/l
3.82
50
118
851
6486
1.64
21.14
7.2
6.5
2.85
2.89
%
0.21
802
6048
47
99
4.86
21.11
2.4
2.2
649.09
658.87
ml
0.05
32
56
294
1667
1.93
21.00
11.0
7.9
0.78
0.98
mmol/l
0.34
251
1366
570
3933
1.68
20.89
3.8
3.2
—
—
—
0
0
93
319
3.03
20.85
2.3
2.0
124.70
129.99
g/l
0.92
75
244
1103
8990
1.67
20.80
6.6
4.4
600.00
1908.33
e6/l
1.07
56
120
180
867
2.21
19.99
13.7
9.5
23.84
24.31
mmol/l
1.00
174
850
135
579
2.45
19.61
1.5
2.2
8.00
7.20
g/l
5.44
124
530
135
579
2.45
19.61
1.5
2.2
4.36
4.18
g/l
1.60
123
532
135
579
2.45
19.61
1.5
2.2
3.77
3.79
g/l
0.04
124
531
300
1748
1.87
19.61
1.3
1.3
414.04
466.35
titre
0.39
57
375
943
7463
1.60
19.36
5.4
3.7
0.22
0.21
estimate
0.03
173
1518
129
552
2.45
18.83
1.6
2.2
2.99
2.93
g/l
0.25
118
505
936
7427
1.59
18.74
5.4
3.7
20.04
0.85
estimate
1.00
206
1624
289
1690
1.86
18.60
11.2
7.9
5.09
5.16
kpa
0.50
279
1623
289
1691
1.86
18.56
11.2
7.9
11.14
12.22
kpa
3.58
275
1625
1205
10175
1.66
18.53
5.3
3.8
14.77
14.90
pmol/l
1.09
1107
9151
922
7339
1.57
17.82
5.5
3.7
0.00
0.00
estimate
-0.00
202
1596
384
2470
1.72
17.81
1.5
1.5
2.74
2.67
g/l
0.27
249
1523
988
7997
1.58
17.69
10.6
9.6
4.62
4.17
e9/l
6.96
874
6937
500
3460
1.63
17.50
5.8
4.0
86.96
86.31
%
0.20
483
3394
37
75
5.02
17.39
1.2
1.3
1.22
1.17
nmol/l
0.08
25
54
87
319
2.82
17.32
1.8
4.1
—
—
—
0
0
92
349
2.73
17.17
3.6
2.4
60.34
61.23
%
0.13
85
339
112
469
2.49
17.12
3.9
3.1
520.81
409.24
mg/l
0.31
59
192
827
6460
1.55
17.10
3.2
2.7
—
—
estimate
—
0
0
83
299
2.87
17.07
5.3
3.5
—
—
—
0
0
249
1425
1.88
17.06
2.0
2.3
0.22
0.21
g/l
1.48
227
1336
82
296
2.86
16.80
7.0
3.2
27.52
28.75
mg/l
0.12
65
194
117
506
2.41
16.68
5.0
3.6
23.73
24.94
mmol/l
3.85
111
481
94
368
2.65
16.50
1.1
1.2
376.25
116.18
titre
—
8
34
163
814
2.11
16.45
1.4
2.0
1.07
1.53
g/l
2.93
149
741
280
1685
1.79
16.26
11.4
8.0
7.41
7.41
ph
0.13
157
949
160
813
2.07
15.41
3.6
2.2
1.42
1.22
%
1.29
160
808
560
4090
1.55
15.16
5.1
3.1
0.32
0.45
e6/l
1.50
437
3052
114
509
2.33
15.13
1.6
2.2
9.36
10.61
g/l
3.26
102
457
1457
13169
1.82
15.10
13.2
6.2
47.01
39.23
mmol/mol
92.53
1384
12175
402
2719
1.63
15.07
4.3
2.7
538.63
552.18
mosm/kgh2o
0.53
367
2372
1390
12400
1.72
15.04
6.9
4.7
2.02
1.98
mu/l
0.53
1303
11246
51
148
3.52
15.03
2.0
1.3
76.83
105.39
mu/l
0.24
45
131
395
2669
1.63
14.84
5.1
3.7
331.19
888.88
ng/l
0.91
332
2165
130
623
2.18
14.56
2.1
1.9
4.24
2.46
ug/l
0.68
119
553
1077
9093
1.52
14.33
4.4
3.2
75.06
51.43
u/l
8.07
991
8485
782
6228
1.48
13.58
16.0
11.3
0.01
0.00
e9/l
0.46
643
5124
129
636
2.11
13.44
2.9
3.4
4.17
4.47
pmol/l
2.97
113
566
84
347
2.50
13.24
1.4
1.2
7.72
5.92
iu/ml
—
5
5
221
1314
1.79
13.22
2.0
1.5
—
—
—
0
0
1478
13528
1.79
13.16
27.7
15.4
25.03
26.00
mg/l
0.50
1332
11116
1186
10299
1.52
13.15
5.4
4.3
15.39
12.16
mm/h
8.95
1103
9560
416
2923
1.56
13.03
3.1
3.1
2.47
2.45
mmol/l
1.59
376
2641
189
1080
1.85
12.87
3.1
2.5
5.92
6.04
ph
0.97
147
739
245
1514
1.72
12.79
1.9
1.5
—
—
—
0
0
45
135
3.40
12.64
1.6
1.3
297.49
305.81
pmol/l
0.06
36
116
45
136
3.37
12.50
1.2
1.4
—
—
nmol/l
—
0
0
81
340
2.45
12.36
4.0
4.4
—
—
—
0
0
294
1924
1.64
12.33
1.3
1.2
—
—
—
0
0
103
482
2.21
12.25
1.3
1.2
—
—
—
0
0
612
4713
1.47
12.23
6.3
6.3
—
—
—
0
0
45
138
3.32
12.22
1.3
1.4
1.00
0.19
nmol/l
0.48
28
111
31
73
4.31
12.22
2.5
2.0
514.05
499.72
min
0.29
22
46
395
2784
1.55
12.08
1.3
1.2
1.44
1.58
u/ml
0.15
119
742
74
302
2.52
11.99
2.6
2.7
34.26
35.44
umol/l
0.14
69
273
77
322
2.46
11.85
1.6
1.3
8.36
7.88
u/l
0.16
68
261
29
69
4.26
11.29
2.6
2.0
191.56
125.26
ug/min
—
9
19
181
1069
1.78
11.02
2.0
2.9
10.27
10.84
g/l
0.95
171
985
109
544
2.07
11.01
1.8
1.7
0.37
0.33
mg/l
0.34
57
255
1416
12946
1.61
11.00
7.6
4.2
2.36
1.27
mmol/l
56.60
1326
11785
130
693
1.95
10.93
4.3
3.4
1.02
1.02
ratio
0.64
122
630
187
1119
1.76
10.88
3.2
2.8
354.59
206.08
ng/l
1.75
169
1020
43
138
3.17
10.88
1.4
1.2
55.70
69.63
mmol/l
1.77
33
108
207
1277
1.71
10.81
4.8
4.6
0.07
0.10
%
0.59
69
362
268
1772
1.61
10.68
2.2
1.7
—
—
—
0
0
214
1337
1.69
10.66
4.7
4.5
0.95
0.88
%
0.11
73
420
50
178
2.86
10.59
2.0
1.8
3.65
4.76
mmol/24h
1.67
41
161
354
2512
1.52
10.31
4.5
2.9
1.36
0.99
e6/l
0.90
215
1391
235
1517
1.64
10.31
2.5
2.7
8.92
8.73
umol/l
0.06
195
1357
191
1169
1.72
10.25
8.2
3.4
1.21
1.23
mmol/l
1.53
169
1004
43
145
3.02
10.04
1.7
2.0
—
—
—
0
0
204
1280
1.68
9.98
4.3
4.4
1.04
0.68
%
0.54
68
398
43
149
2.94
9.58
1.3
1.4
26.17
25.02
ng/l
0.08
43
149
119
645
1.91
9.54
1.3
1.3
—
—
—
0
0
19
37
5.18
9.37
1.2
1.6
190.37
158.83
mmol/24h
0.56
19
37
416
3104
1.45
9.32
6.4
4.8
—
—
—
0
0
316
2243
1.50
9.09
4.5
3.1
2.30
1.75
e6/l
0.58
169
1115
553
4366
1.40
8.98
5.7
3.8
0.00
0.00
estimate
0.50
157
1451
149
883
1.75
8.96
5.0
5.2
—
—
—
0
0
130
740
1.82
8.95
6.1
4.2
36.93
36.90
°c
0.33
130
734
82
399
2.11
8.90
1.6
1.5
277.40
263.49
ug/g
0.24
46
241
200
1289
1.63
8.79
5.1
4.9
0.08
0.14
%
0.56
62
346
65
290
2.29
8.73
6.0
3.9
2.48
2.62
mmol/l
0.14
49
192
64
286
2.29
8.57
1.2
1.3
20.67
45.47
u/l
1.31
57
245
20
45
4.49
8.37
1.0
1.0
—
—
—
0
0
193
1250
1.61
8.31
2.6
2.6
164.75
40.40
u/l
0.48
165
1063
218
1463
1.56
8.07
6.8
3.7
7.36
7.34
ph
0.56
178
1036
429
3302
1.40
7.91
4.6
3.6
0.25
0.05
—
8
38
682
5663
1.34
7.79
5.7
3.7
0.60
0.03
estimate
0.49
173
1326
252
1769
1.50
7.56
3.2
3.3
4.72
4.42
e9/l
0.65
219
1525
19
45
4.26
7.48
1.0
1.1
—
—
—
0
0
1432
13376
1.49
7.46
7.9
5.1
6.91
5.97
mmol/l
59.91
1325
12124
1442
13509
1.49
7.19
8.5
5.0
1.16
1.43
mmol/l
140.70
1365
12399
230
1602
1.51
7.16
1.5
1.4
—
—
—
0
0
26
80
3.29
7.12
2.3
2.4
10.67
7.95
mmol/l
2.70
26
80
1503
14210
1.57
7.11
35.6
18.0
139.49
139.81
mmol/l
5.52
1486
13918
54
246
2.23
6.96
1.5
1.2
249.63
282.05
u/ml
0.40
32
141
298
2198
1.43
6.90
1.3
1.3
9.81
10.94
u/ml
0.11
126
860
70
356
2.01
6.81
1.4
1.2
—
—
—
0
0
314
2346
1.42
6.76
1.3
1.3
44.87
36.36
iu/ml
0.39
81
718
487
3910
1.35
6.74
5.3
3.1
0.17
0.04
estimate
0.74
161
1243
56
263
2.17
6.72
1.7
1.4
—
—
—
0
0
1469
13853
1.50
6.68
9.4
5.7
2.31
2.70
mmol/l
43.72
1399
12730
61
297
2.09
6.68
1.5
1.6
280.45
281.21
mu/l
0.01
53
276
1503
14249
1.54
6.58
36.1
18.2
4.03
4.00
mmol/l
5.92
1484
13935
241
1723
1.47
6.57
1.6
1.5
—
—
—
0
0
17
41
4.18
6.55
2.5
1.4
—
—
—
0
0
20
55
3.67
6.48
1.7
2.1
92.33
74.08
umol/l
—
9
38
452
3613
1.34
6.39
3.9
2.8
0.11
0.02
0.37
27
97
1445
13610
1.45
6.34
8.5
5.1
4.28
4.59
mmol/l
18.72
1372
12582
17
43
3.98
6.17
5.1
5.0
—
—
—
0
0
28
101
2.80
5.90
1.2
1.3
19.88
27.85
u/l
0.65
18
83
59
300
2.00
5.79
2.9
3.3
0.89
0.80
nmol/l
1.02
43
248
49
241
2.06
5.29
1.7
1.4
157.39
159.98
au/ml
0.05
16
67
49
242
2.06
5.23
1.3
1.2
—
—
—
0
0
22
75
2.96
5.15
1.2
1.3
—
—
—
0
0
51
258
2.01
5.11
4.2
4.0
1.57
1.57
%
0.00
44
232
30
122
2.49
5.05
1.1
1.2
—
51.76
—
0
9
201
1460
1.43
5.02
2.5
1.9
0.00
0.02
estimate
0.78
39
286
39
179
2.21
5.02
1.2
1.3
—
—
—
0
0
678
5868
1.26
4.99
2.3
1.9
2.61
1.33
mmol/l
23.39
553
4804
25
94
2.68
4.92
1.8
1.5
122.60
85.97
umol/l
1.57
25
94
59
319
1.88
4.89
1.2
1.6
—
—
—
0
0
26
101
2.60
4.81
1.5
2.2
6.85
6.85
mmol/l
0.00
12
59
24
90
2.69
4.75
1.0
1.0
—
—
—
0
0
638
5511
1.25
4.70
2.5
2.2
—
—
—
0
0
23
85
2.73
4.68
1.1
1.1
95.65
108.61
pmol/l
0.51
23
85
45
225
2.03
4.68
2.2
2.4
0.93
0.91
%
0.09
36
164
19
63
3.04
4.67
1.1
3.0
48.31
53.89
mg/l
0.22
13
46
14
31
4.55
4.56
1.5
1.4
56.00
282.32
nmol/24h
0.56
14
31
96
616
1.59
4.37
2.2
1.9
—
—
—
0
0
206
1542
1.38
4.34
2.4
2.5
157.72
143.29
ug/g
0.29
164
1226
22
84
2.64
4.23
3.5
1.9
221.96
137.93
ng/l
1.10
22
84
24
96
2.52
4.22
1.5
1.3
1.54
1.13
promille
0.63
18
78
89
566
1.60
4.21
4.7
6.0
0.83
0.87
%
0.34
89
528
14
41
3.44
4.19
2.8
1.7
—
—
—
0
0
172
1261
1.41
4.10
1.3
1.4
—
—
—
0
0
31
142
2.21
4.06
11.9
2.2
—
—
—
0
0
66
1070
0.60
4.05
1.3
1.4
—
—
—
0
0
244
1898
1.33
4.02
7.4
4.7
27.83
32.45
%
10.09
193
1203
61
357
1.74
3.97
3.7
3.4
1.35
2.04
index
0.62
34
182
27
119
2.29
3.88
1.4
2.0
3.06
1.45
u/field
0.67
18
64
61
360
1.72
3.86
2.2
2.1
11.69
11.78
mg/l
0.02
56
339
90
1336
0.66
3.76
2.3
2.2
5.08
3.59
ratio
1.21
71
1084
29
135
2.17
3.68
1.7
1.9
—
—
—
0
0
33
163
2.05
3.61
4.7
4.5
—
—
—
0
0
15
51
2.96
3.57
3.1
2.0
280.80
740.18
e6/l
—
10
44
9
266
0.33
3.56
17.1
8.6
104.67
105.46
mmol/l
—
9
229
9
266
0.33
3.56
17.1
8.5
10.56
11.27
mmol/l
—
9
229
36
186
1.96
3.49
2.4
4.1
60.48
56.82
%
0.51
29
162
25
112
2.25
3.49
1.2
1.1
—
—
—
0
0
10
22
4.57
3.43
2.2
1.5
114.30
125.50
ug/l
—
10
22
389
3292
1.24
3.26
5.9
3.8
1.02
1.02
kg/l
0.17
290
2116
81
538
1.53
3.24
1.6
1.8
8.04
7.28
iu/ml
0.09
14
128
124
897
1.41
3.23
1.4
1.4
—
—
—
0
0
104
729
1.45
3.21
1.2
1.2
47.72
142.67
u/ml
5.21
31
258
14
49
2.87
3.19
1.0
1.8
38.22
40.60
g/l
0.79
14
49
47
275
1.73
3.12
1.9
1.8
4.80
4.01
iu/l
0.17
14
103
29
145
2.02
3.11
1.2
1.1
—
—
—
0
0
94
652
1.47
3.08
3.4
2.7
—
—
—
0
0
245
1981
1.28
3.04
1.5
1.3
—
—
—
0
0
19
81
2.36
2.99
1.1
1.0
—
—
—
0
0
73
485
1.53
2.95
1.7
1.9
22.12
21.04
s
0.28
66
440
44
259
1.72
2.88
8.6
1.8
—
—
—
0
0
10
27
3.72
2.88
5.1
6.1
8.56
8.63
mmol/l
—
10
27
8
18
4.46
2.79
7.6
9.6
7.15
5.73
mmol/l
—
8
18
10
28
3.59
2.78
1.1
1.1
—
—
—
0
0
24
117
2.07
2.77
1.3
1.2
—
—
—
0
0
26
133
1.97
2.66
1.2
1.1
—
—
—
0
0
12
43
2.80
2.65
3.5
1.7
983.00
35021.75
e6/l
—
7
32
28
148
1.91
2.61
1.8
1.4
24.94
25.07
%
0.01
17
90
65
949
0.67
2.57
2.1
1.9
3.50
3.51
mmol/l
0.03
43
700
5
7
7.16
2.55
1.0
1.3
1.87
2.09
umol/24h
—
5
7
13
50
2.61
2.53
7.9
6.8
6.46
13.51
ug/l
—
8
33
41
249
1.66
2.44
3.1
3.3
4.38
4.37
e9/l
0.00
41
249
18
83
2.18
2.41
2.4
2.9
16.12
16.30
%
0.09
18
83
22
110
2.01
2.41
1.4
1.5
0.15
0.23
nmol/l
1.51
17
76
200
1629
1.26
2.36
3.7
2.3
11.75
14.10
nmol/l
4.81
178
1496
35
206
1.71
2.35
1.1
1.1
—
—
—
0
0
37
223
1.67
2.28
1.1
1.1
—
—
—
0
0
53
351
1.53
2.24
1.1
1.1
—
—
—
0
0
5
9
5.57
2.21
2.0
1.3
—
—
—
0
0
466
4149
1.17
2.18
7.6
6.1
—
—
—
0
0
35
211
1.67
2.17
13.8
2.5
—
—
—
0
0
25
137
1.84
2.14
2.0
2.1
92.08
3626.17
u/l
—
8
43
573
5202
1.15
2.06
5.6
3.1
—
—
—
0
0
12
50
2.41
2.02
1.9
1.8
2.04
12.60
nmol/l
0.68
12
43
8
26
3.09
2.01
1.9
1.8
—
—
—
0
0
1506
14698
1.25
1.98
37.8
20.3
97.85
80.80
umol/l
18.32
1496
14520
49
329
1.50
1.97
8.1
1.8
—
—
—
0
0
49
331
1.49
1.93
8.1
1.8
—
—
—
0
0
49
331
1.49
1.93
8.2
1.8
—
—
—
0
0
16
78
2.06
1.91
1.1
1.5
—
—
—
0
0
29
173
1.69
1.90
1.6
1.6
73.16
59.74
%
1.26
20
110
48
327
1.48
1.83
3.9
1.8
—
—
—
0
0
66
478
1.40
1.82
1.1
1.2
0.16
1.28
u/ml
—
7
33
1487
14516
1.22
1.80
18.1
11.8
30.19
27.21
u/l
6.17
1449
14043
9
35
2.58
1.80
1.4
1.3
9.41
9.01
mmol/l
—
9
35
15
74
2.04
1.75
1.4
1.6
—
—
—
0
0
6
19
3.17
1.66
2.0
2.1
21.13
16.97
umol/l
—
6
19
84
643
1.32
1.66
1.3
1.3
—
—
—
0
0
31
196
1.59
1.66
1.5
1.4
600.52
1840.94
e6/l
3.57
25
144
18
98
1.85
1.62
1.3
1.1
384.23
361.21
nmol/l
0.17
13
86
5
14
3.58
1.61
1.0
1.3
—
—
—
0
0
183
1543
1.21
1.61
3.6
4.5
101.18
29.45
ug/l
0.53
149
1285
13
63
2.07
1.60
1.2
1.2
—
—
—
0
0
15
77
1.96
1.59
1.3
1.2
137.13
140.13
nmol/l
0.10
15
77
7
26
2.70
1.58
2.3
2.6
4.71
1220.46
ug/l
—
7
26
17
92
1.86
1.56
1.1
1.3
—
—
—
0
0
17
92
1.86
1.56
5.6
5.0
70.12
54.42
u/ml
—
6
30
44
306
1.45
1.55
8.9
1.8
—
—
—
0
0
54
391
1.39
1.53
4.4
6.8
1.68
1.30
mmol/l
1.02
47
335
28
177
1.59
1.52
1.5
1.4
43852.65
67818.08
e6/l
0.19
17
106
43
300
1.44
1.50
3.3
3.2
58.19
58.27
%
0.02
43
300
53
385
1.39
1.48
1.9
1.6
11694.92
12095.44
e6/l
0.04
36
270
22
132
1.68
1.46
1.8
1.5
138.02
251.90
pmol/l
0.79
22
132
9
40
2.26
1.40
2.7
2.5
0.55
0.62
mmol/l
—
9
40
383
4216
0.88
1.39
3.4
3.3
1.02
0.78
ug/l
0.89
266
2793
22
134
1.65
1.39
3.9
2.7
16.08
11.04
index
0.65
13
73
59
443
1.34
1.37
1.6
1.6
20.64
17.34
u/ml
0.19
14
91
5
17
2.95
1.36
1.0
1.1
0.02
0.02
u/ml
—
5
17
5
17
2.95
1.36
1.4
1.0
176.56
95.32
ng/l
—
5
11
1152
11112
1.12
1.33
35.0
20.0
330.74
332.70
g/l
9.33
1147
11039
115
947
1.23
1.32
1.2
1.2
—
—
—
0
0
20
121
1.66
1.31
1.2
1.2
—
—
—
0
0
8
34
2.36
1.29
2.8
1.1
—
—
—
0
0
5
18
2.78
1.28
1.2
1.4
58.80
69.06
ug/l
—
5
18
5
18
2.78
1.28
1.2
1.4
1.16
1.18
mmol/l
—
5
18
28
412
0.67
1.27
1.4
1.7
—
—
—
0
0
37
262
1.42
1.23
1.1
1.6
—
—
—
0
0
9
45
2.01
1.23
3.9
1.6
—
—
—
0
0
139
1176
1.20
1.23
5.9
3.6
—
—
—
0
0
5
19
2.64
1.21
1.4
1.3
—
—
—
0
0
21
132
1.60
1.20
3.4
2.5
—
—
—
0
0
42
307
1.38
1.18
1.1
1.1
—
—
—
0
0
96
787
1.23
1.17
2.6
2.0
0.00
1.07
estimate
0.50
21
234
43
317
1.37
1.15
1.4
1.3
17.25
27.22
iu/l
2.03
38
263
7
31
2.26
1.10
1.3
1.2
—
—
—
0
0
20
128
1.57
1.08
1.3
1.3
—
—
—
0
0
82
670
1.24
1.05
2.0
1.6
—
—
—
0
0
87
716
1.23
1.04
2.6
2.3
—
—
—
0
0
9
48
1.88
1.00
1.4
1.3
—
—
—
0
0
7
35
2.00
1.00
1.0
1.1
—
—
—
0
0
20
131
1.53
1.00
1.2
1.1
—
—
—
0
0
14
224
0.62
0.98
2.4
2.4
—
—
—
0
0
14
84
1.67
0.98
1.0
1.0
—
—
—
0
0
6
27
2.23
0.93
21.8
8.8
6.73
4.89
kpa
—
6
27
12
70
1.72
0.92
1.2
1.3
11.34
26.18
umol/l
2.97
12
60
6
28
2.15
0.91
1.0
4.1
—
—
—
0
0
19
127
1.50
0.88
1.8
1.4
—
—
—
0
0
153
1350
1.15
0.86
1.6
1.5
—
—
—
0
0
727
6955
1.08
0.84
5.2
5.6
2.41
2.98
ug/l
0.94
648
6293
10
57
1.76
0.83
1.2
1.2
421.07
222.41
iu/ml
—
10
57
6
32
1.88
0.82
1.2
1.1
136.50
139.13
mmol/l
—
6
23
6
33
1.82
0.79
1.0
1.0
—
—
—
0
0
22
156
1.42
0.79
1.2
1.2
—
—
—
0
0
9
54
1.67
0.74
1.8
3.4
—
—
—
0
0
1508
14900
1.12
0.72
42.5
23.6
243.22
242.00
e9/l
0.28
1480
14588
9
57
1.58
0.71
2.6
2.9
—
—
—
0
0
1508
14903
1.12
0.70
42.3
23.5
91.24
91.47
fl
1.05
1495
14708
1508
14904
1.12
0.70
42.2
23.4
30.21
30.48
pg
6.66
1495
14707
1508
14905
1.12
0.69
42.4
23.5
4.48
4.52
e12/l
1.60
1475
14536
1508
14905
1.12
0.69
43.5
24.0
40.03
40.72
%
4.20
1495
14699
1508
14906
1.12
0.69
42.5
23.5
7.36
6.72
e9/l
27.06
1475
14540
1508
14907
1.12
0.68
42.7
23.7
133.99
136.78
g/l
8.57
1494
14716
11
70
1.58
0.65
1.2
1.2
1.05
1.08
ratio
0.58
11
60
10
153
0.65
0.62
1.2
1.2
—
—
—
0
0
408
3863
1.07
0.61
1.4
1.3
—
—
—
0
0
5
30
1.67
0.61
1.0
4.1
—
—
—
0
0
1127
11032
1.07
0.60
33.7
19.0
14.11
13.69
%
17.04
1118
10862
51
427
1.20
0.59
1.1
1.1
—
—
—
0
0
23
175
1.32
0.58
1.6
1.5
—
—
—
0
0
8
54
1.48
0.57
1.4
1.4
26.38
26.48
%
—
8
49
19
141
1.35
0.56
1.8
1.3
—
—
—
0
0
9
60
1.50
0.54
1.8
3.3
—
—
—
0
0
25
196
1.28
0.52
1.1
1.2
1.87
5.54
u/ml
1.23
15
98
21
161
1.31
0.52
1.6
1.4
—
—
—
0
0
12
83
1.45
0.51
1.3
1.1
—
—
—
0
0
63
548
1.16
0.50
2.5
3.6
32.14
2485.62
u/ml
0.76
54
471
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
101
913
1.11
0.46
1.2
1.3
—
—
—
0
0
22
174
1.27
0.45
1.3
1.4
—
—
—
0
0
20
158
1.27
0.41
1.2
1.1
—
—
—
0
0
28
231
1.22
0.41
2.2
2.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
5.30
—
0
7
0
15
0.00
0.41
0.0
1.7
—
54.33
—
0
15
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
8
61
1.31
0.39
1.0
1.0
1937.75
1317.26
miu/ml
—
8
61
0
19
0.00
0.39
0.0
4.2
—
1.76
—
0
19
40
463
0.86
0.39
1.2
1.2
—
—
—
0
0
9
68
1.33
0.37
1.2
1.1
—
—
—
0
0
10
72
1.39
0.37
1.1
1.5
8.80
7.36
umol/l
—
10
45
15
191
0.78
0.36
1.1
1.1
0.52
1.71
u/ml
—
6
108
9
71
1.27
0.36
1.2
1.6
—
—
—
0
0
12
90
1.34
0.35
1.4
1.1
—
—
—
0
0
20
162
1.24
0.35
1.2
1.2
—
—
—
0
0
21
172
1.22
0.34
1.3
1.2
—
—
—
0
0
12
91
1.32
0.33
2.6
1.7
—
—
—
0
0
18
145
1.24
0.33
1.0
1.3
—
—
—
0
0
44
495
0.89
0.31
1.3
1.7
—
—
—
0
0
7
97
0.72
0.31
1.9
2.2
77.14
69.70
%
—
7
90
34
296
1.15
0.30
1.6
1.3
21.71
39.90
e6/l
0.34
24
228
7
54
1.30
0.30
1.0
1.1
—
3.31
—
0
8
13
102
1.28
0.30
1.2
2.3
41.75
38.38
%
0.33
13
102
7
56
1.25
0.29
1.3
1.1
—
—
—
0
0
7
57
1.23
0.29
1.7
2.4
128.43
142.20
nmol/l
—
7
50
34
299
1.14
0.27
1.6
1.4
1544.32
844.07
e6/l
0.30
25
240
9
72
1.25
0.25
1.1
1.3
30.67
27.78
umol/l
—
9
64
92
860
1.07
0.25
1.3
1.3
—
55.92
—
0
69
91
970
0.93
0.23
1.5
1.3
—
—
—
0
0
31
276
1.13
0.22
1.6
1.3
—
—
—
0
0
13
107
1.22
0.21
2.5
2.7
32.74
18.13
mg/l
—
8
81
5
42
1.19
0.21
1.2
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
4.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
8
102
0.78
0.21
1.5
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
3.4
—
0.15
—
0
13
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
50
1.20
0.19
1.0
1.0
—
0.30
—
0
12
6
52
1.15
0.19
1.0
2.4
14.22
171.74
ug/l
—
6
46
10
121
0.83
0.18
1.2
1.2
7.40
12.52
u/l
—
10
109
35
381
0.92
0.16
2.9
3.7
318.86
1127.25
u/ml
0.60
30
361
9
78
1.15
0.15
1.0
1.0
—
—
—
0
0
98
938
1.05
0.15
2.5
2.5
9.90
18.95
au/ml
—
7
78
9
82
1.10
0.15
1.8
2.7
674.67
600.06
e6/l
—
9
70
27
247
1.09
0.13
1.5
1.3
—
—
—
0
0
10
85
1.18
0.12
2.8
3.0
271.60
224.67
e6/l
—
10
78
13
115
1.13
0.10
1.0
1.0
275.50
339.79
ng/l
—
8
76
33
310
1.07
0.10
1.2
1.2
4.45
3.70
mmol/l
1.71
33
287
13
116
1.12
0.09
1.0
1.0
1030.29
699.23
ng/l
—
7
75
61
586
1.04
0.09
1.1
1.1
—
—
—
0
0
5
61
0.82
0.08
1.4
1.8
0.00
0.05
estimate
—
5
61
5
61
0.82
0.08
1.2
1.1
—
—
—
0
0
37
353
1.05
0.07
1.4
1.2
569.38
612.22
mg/l
0.25
37
329
14
153
0.91
0.07
1.8
2.2
—
—
—
0
0
18
167
1.08
0.07
1.6
1.4
7.82
6.25
mmol/l
1.27
18
154
17
182
0.93
0.05
2.2
1.5
—
—
—
0
0
17
182
0.93
0.05
2.2
1.5
—
—
—
0
0
17
182
0.93
0.05
2.2
1.5
—
—
—
0
0
17
182
0.93
0.05
2.2
1.5
—
—
—
0
0
10
91
1.10
0.04
1.2
1.1
234.70
292.55
mg/l
—
10
78
21
200
1.05
0.03
1.2
1.1
—
—
—
0
0
21
201
1.05
0.03
1.2
1.1
—
—
—
0
0
39
380
1.03
0.03
1.1
1.1
—
—
—
0
0
14
148
0.95
0.02
1.1
1.1
0.69
0.86
u/ml
—
5
61
46
468
0.98
0.01
20.4
9.9
—
—
—
0
0
29
283
1.03
0.01
1.2
1.3
205.23
194.39
miu/ml
0.06
12
108
15
144
1.04
0.00
1.0
1.2
—
86.38
—
0
10
13
126
1.03
0.00
1.6
2.4
1319.77
1179.47
e6/l
0.20
13
115
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
166.20
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
249.80
—
0
5
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
35.65
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.17
—
0
8
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_HYPERLIPMIX and mortality.

Females

Parameter HR [95% CI] p-value
E4_HYPERLIPMIX 1.44 [1.28, 1.62] < 0.001
Birth year 0.996 [0.99, 1.0] 0.339

During the follow-up period (1.1.1998 — 31.12.2019), 748 out of 2730 females with E4_HYPERLIPMIX died.

Males

Parameter HR [95% CI] p-value
E4_HYPERLIPMIX 1.599 [1.45, 1.76] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 1357 out of 4799 males with E4_HYPERLIPMIX died.

Mortality risk

Mortality risk for people of age

years, who have E4_HYPERLIPMIX.

N-year risk Females Males
1 0.169% 0.275%
5 0.803% 1.708%
10 2.097% 4.536%
15 4.065% 8.75%
20 7.427% 14.817%

Relationships between endpoints

Index endpoint: E4_HYPERLIPMIX – Mixed hyperlipidaemia

GWS hits: 7

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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