Progressive vascular leukoencephalopathy

I9_PROGVASC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I67.3
  • Cause of death: ICD-10 I67.3

2 out of 7 registries used, show all original rules.

1813

4. Check minimum number of events

None

1813

5. Include endpoints

None

1813

6. Filter based on genotype QC (FinnGen only)

1562

Control definitions (FinnGen only)

Control exclude
I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I67
Name in latin
Leucoencephalopathia vascularis progressiva

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8396 4988 3358
Only index persons 7636 4604 3032
Unadjusted period prevalence (%)
Whole population 0.12 0.14 0.09
Only index persons 0.15 0.17 0.12
Median age at first event (years)
Whole population 80.45 81.63 78.75
Only index persons 80.80 81.89 79.13

-FinnGen-

Key figures

All Female Male
Number of individuals 1562 846 716
Unadjusted period prevalence (%) 0.31 0.30 0.33
Median age at first event (years) 80.51 80.98 79.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1623
Matched controls
16230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R41.3
ICD-10 Finland
Other amnesia
12.3
313.0
343
345
R4110
NOMESCO Finland
Physiotherapy
6.5
310.7
994
3185
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
88.1
307.7
374
55
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
12.0
307.7
878
1448
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
127.4
307.7
381
39
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
4503599627370496.0
307.7
1621
54
Z2221
NOMESCO Finland
Medical doctor
5.2
241.8
871
2944
G30.1
ICD-10 Finland
Alzheimer disease with late onset
5.4
208.8
551
1417
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
4.6
202.3
846
3116
Z71.8
ICD-10 Finland
Other specified counselling
4.4
194.3
881
3421
XA800
NOMESCO Finland
Neuropsychological investigation
16.8
158.1
135
87
R4120
NOMESCO Finland
Occupational therapy
7.8
157.6
237
348
Z3226
NOMESCO Finland
Physiotherapist
4.2
157.4
584
1910
P20
ICPC
Memory disturbance
3.9
153.8
747
2937
ZXD10
NOMESCO Finland
Scheduled procedure
3.8
149.4
992
4761
AA1AD
NOMESCO Finland
CT of head and brain
3.7
146.8
860
3796
R5110, ,
SPAT
4.6
145.3
431
1185
Z01.9
ICD-10 Finland
Special examination, unspecified
6.2
142.9
272
509
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
7.2
142.5
231
367
Z76.0
ICD-10 Finland
Issue of repeat prescription
3.7
136.2
640
2426
Z3231
NOMESCO Finland
Registered nurse
3.5
132.7
756
3230
A28
ICPC
Limited function/disability NOS
3.5
132.3
813
3638
N06DX01
ATC
memantine; oral
3.7
119.6
511
1798
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
323.0
118.9
119
*
XF400
NOMESCO Finland
ECG with 12 standard connections
3.5
115.2
532
1962
F01.9
ICD-10 Finland
Vascular dementia, unspecified
9.7
111.9
135
150
Z01.7
ICD-10 Finland
Laboratory examination
3.6
111.6
473
1646
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
4.7
106.4
279
685
R53
ICD-10 Finland
Malaise and fatigue
3.1
105.1
709
3250
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
6.2
101.0
185
330
ZXE00
NOMESCO Finland
One hour or less
2.8
92.8
858
4584
WX002
NOMESCO Finland
Sedation and analgesia
3.0
88.2
556
2410
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
7.3
87.9
134
197
ZXA05
NOMESCO Finland
Left side
2.8
86.9
703
3475
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.4
85.8
371
1287
R4130
NOMESCO Finland
Speech therapy
9.9
84.1
99
106
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.7
79.6
640
3123
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
79.3
453
1844
ZXA00
NOMESCO Finland
Right side
2.7
79.0
717
3713
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
78.0
803
4415
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.3
71.1
322
1139
A23
ICPC
Risk factor NOS
4.0
71.0
226
634
WX110, ,
SPAT
5.3
70.6
151
309
Z71.9
ICD-10 Finland
Counselling, unspecified
3.8
69.3
240
714
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.2
68.6
319
1145
Z73.6
ICD-10 Finland
Limitation of activities due to disability
11.2
67.4
72
67
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.4
67.2
829
4856
R42
ICD-10 Finland
Dizziness and giddiness
2.5
65.7
632
3299
U13
ICPC
Bladder symptom/complaint other
5.1
64.4
142
298
EB1AA, ,
SPAT
4.5
63.2
165
398
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
62.9
60
*
XCK10
NOMESCO Finland
Photography of fundus of eye
3.1
62.5
316
1186
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.5
62.0
244
787
Z71
ICD-10 Finland
Persons encountering health services for other counselling and medical advice, not elsewhere classified
6.8
61.3
98
151
A97
ICPC
No disease
2.6
59.9
483
2305
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
58.6
373
1581
N05AX08
ATC
risperidone; systemic
3.0
58.6
302
1143
B01AC04
ATC
clopidogrel; oral
2.6
57.6
457
2159
N06DA03
ATC
rivastigmine; oral, transdermal
3.3
57.2
251
864
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.2
57.2
161
411
PA6AD
NOMESCO Finland
CT of neck arteries
5.9
56.9
105
187
C10AA05
ATC
atorvastatin; oral
2.3
55.1
917
5931
K90
ICPC
Stroke/cerebrovascular accident
10.5
54.9
61
60
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
3.2
54.8
249
874
ZXD35
NOMESCO Finland
Usual procedure
5.1
54.8
120
250
Z2446
NOMESCO Finland
Social worker
3.9
53.8
169
467
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.6
53.5
133
308
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.8
53.2
315
1281
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
118.1
53.1
57
5
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.6
53.1
189
569
ZXD20
NOMESCO Finland
Day surgery
2.8
51.1
306
1249
N06AX11
ATC
mirtazapine; oral
2.2
49.6
680
4018
U72
ICPC
Urethritis
5.6
48.7
95
178
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
247.1
47.3
48
*
N06DA04
ATC
galantamine; oral
3.8
45.8
147
411
WX892
NOMESCO Finland
Monitored bed care
3.2
45.3
203
703
N17
ICPC
Vertigo/dizziness
2.4
44.4
375
1798
M79.6
ICD-10 Finland
Pain in limb
2.1
44.0
793
5134
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.2
43.8
481
2576
M54
ICD-10 Finland
Dorsalgia
2.8
43.5
249
988
Z02.7
ICD-10 Finland
Issue of medical certificate
3.0
43.4
210
760
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.7
43.3
146
422
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.8
43.2
141
399
F03
ICD-10 Finland
Unspecified dementia
3.0
42.9
208
753
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.3
42.8
114
278
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
150.7
42.0
44
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
41.8
217
816
N06AX26
ATC
vortioxetine; oral
3.6
41.3
142
416
K91
ICPC
Cerebrovascular disease
11.6
40.6
42
37
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.6
39.9
98
224
Z2445
NOMESCO Finland
Psychologist
7.7
39.6
56
75
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
66.0
39.3
45
7
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
396.7
39.2
39
*
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
204.9
39.0
40
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
0.4
38.8
305
5680
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
6.0
38.7
70
122
S01.0
ICD-10 Finland
Open wound of scalp
2.7
38.5
225
900
I10
ICD-10 Finland
Essential (primary) hypertension
2.3
38.2
1295
10314
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
4.1
38.1
108
276
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.5
37.7
62
98
A98
ICPC
Health maint/preventive medicine
3.5
37.1
1517
13062
H81
ICPC
Excessive ear wax
2.1
36.9
473
2663
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.4
36.6
140
439
F01.2
ICD-10 Finland
Subcortical vascular dementia
9.2
36.1
44
49
IGY02
NOMESCO Finland
Psychiatric monitoring contact
7.8
35.8
50
66
L28
ICPC
Limited function/disability (L)
2.0
35.5
551
3318
TAB00
NOMESCO Finland
Lumbar puncture
4.3
35.4
93
224
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.1
35.3
100
255
F05.9
ICD-10 Finland
Delirium, unspecified
4.2
34.9
95
235
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
2.1
34.6
438
2446
WYA30, ,
SPAT
10.5
34.3
38
37
SPAT1153
SPAT
Removal of sutures
0.4
33.9
204
4299
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
33.5
350
1813
SPAT1263
SPAT
Sampling
0.5
33.4
303
5441
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.4
33.3
264
1217
R1260
NOMESCO Finland
Evaluation of communicative skills
6.2
33.3
57
94
GD1LA
NOMESCO Finland
GD
5.4
33.1
66
126
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
8.9
32.9
41
47
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.0
32.9
530
3216
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
32.5
226
980
I95.1
ICD-10 Finland
Orthostatic hypotension
2.9
32.4
161
588
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.7
32.3
108
310
EB1SA, ,
SPAT
4.1
32.0
89
224
N06DA02
ATC
donepezil; oral
2.3
31.7
273
1303
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
6.8
31.6
50
76
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.4
31.3
41
50
N30
ICD-10 Finland
Cystitis
2.7
31.1
189
767
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.1
31.0
141
490
N02BE01
ATC
paracetamol; systemic, rectal
2.9
31.0
1494
13000
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
30.9
344
1821
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
8.2
30.8
41
51
N03AG01
ATC
valproic acid; systemic, rectal
3.5
30.7
109
325
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
10.8
30.5
33
31
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.8
30.2
95
261
ZXA10
NOMESCO Finland
Bilateral
2.0
30.1
447
2623
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.2
29.8
122
398
F06.7
ICD-10 Finland
Mild cognitive disorder
3.1
29.8
131
446
N30.0
ICD-10 Finland
Acute cystitis
2.0
29.7
385
2153
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.9
29.5
88
233
R52.9
ICD-10 Finland
Pain, unspecified
2.5
29.5
209
913
M25.5
ICD-10 Finland
Pain in joint
1.9
29.2
491
3000
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
29.1
176
712
XF404
NOMESCO Finland
Ambulatory ECG
2.4
29.1
220
990
C07AB07
ATC
bisoprolol; oral
1.8
29.0
1066
8266
EBA00, ,
SPAT
4.5
28.9
71
162
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
152.7
28.7
30
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
28.7
459
2757
C08CA01
ATC
amlodipine; oral
1.8
28.5
861
6281
U07
ICPC
Urine symptom/complaint other
2.3
28.5
231
1072
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
6.5
28.3
46
72
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.0
28.0
355
1965
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
10.9
27.8
30
28
SPAT1312
SPAT
General health counselling
0.4
27.7
174
3666
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
27.4
1030
7972
N05AH04
ATC
quetiapine; oral
2.1
27.3
284
1459
N06AB10
ATC
escitalopram; oral
2.2
26.7
269
1363
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
26.3
943
7160
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.1
25.9
311
1682
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
25.8
438
2666
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
25.8
239
1170
R51.80
ICD-10 Finland
Headache
2.3
25.7
221
1049
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
5.0
25.7
55
112
XF402
NOMESCO Finland
ECG with work load test
2.2
25.5
250
1252
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
25.2
234
1147
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
25.0
570
3790
M03BC01
ATC
orphenadrine (citrate); systemic
2.1
24.8
291
1559
A02BC02
ATC
pantoprazole; systemic
1.8
24.8
1170
9533
R60.0
ICD-10 Finland
Localized oedema
2.0
24.7
324
1808
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
24.6
488
3112
M54.5
ICD-10 Finland
Low back pain
1.8
24.6
581
3901
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
24.1
135
524
SPAT1301
SPAT
No procedures
0.5
24.1
258
4508
S06.0
ICD-10 Finland
Concussion
2.2
23.9
216
1045
EBA30
NOMESCO Finland
Extraction of root of tooth
2.6
23.8
141
564
R41.0
ICD-10 Finland
Disorientation, unspecified
3.0
23.6
107
371
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
5.0
23.5
51
105
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
23.5
549
3663
WX320
NOMESCO Finland
Spinalanesthesy
1.8
23.5
498
3232
EBA05, ,
SPAT
5.6
23.3
44
80
R05
ICD-10 Finland
Cough
1.9
23.1
379
2271
WW200, ,
SPAT
0.4
23.0
168
3380
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
23.0
341
1979
Z50.1
ICD-10 Finland
Other physical therapy
2.6
22.9
136
544
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.5
22.8
203
3797
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
233.2
22.7
23
*
D12
ICPC
Constipation
2.7
22.6
124
476
SPAT1336
SPAT
Request for examination
3.0
22.6
104
363
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
22.6
128
500
D11
ICPC
Diarrhoea
2.3
22.5
196
933
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
32.8
22.4
29
9
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
3.8
22.3
68
183
G04BD12
ATC
mirabegron; oral
1.9
22.2
305
1722
I67.8
ICD-10 Finland
Other specified cerebrovascular diseases
52.8
22.1
26
5
L17
ICPC
Foot/toe symptom/complaint
1.7
22.1
556
3773
R55
ICD-10 Finland
Syncope and collapse
2.0
22.1
276
1508
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
22.0
437
2771
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.2
22.0
88
283
L84
ICD-10 Finland
Corns and callosities
3.2
22.0
91
299
Z01.3
ICD-10 Finland
Examination of blood pressure
4.7
21.8
51
112
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
21.8
533
3587
A04
ICPC
Weakness/tiredness general
1.8
21.6
366
2212
J01DB01
ATC
cefalexin; oral
1.8
21.5
1275
10829
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
21.4
381
2336
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
3.5
21.4
76
227
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
21.3
559
3828
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
8.0
21.3
29
37
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
20.7
235
1240
G46.8*I67.9
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
33.0
20.2
26
8
F32
ICD-10 Finland
Depressive episode
3.4
20.0
73
222
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
+∞
19.8
19
*
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
19.8
19
*
WX212
NOMESCO Finland
Femoral plexus blockade
3.0
19.7
87
297
WX290, ,
SPAT
4.1
19.5
53
131
C10AA01
ATC
simvastatin; oral
1.6
19.5
913
7187
G30.8
ICD-10 Finland
Other Alzheimer disease
2.7
19.5
110
429
SPAT1310
SPAT
Counselling related to known health issue
0.5
19.4
224
3878
P70
ICPC
Dementia
2.6
19.3
115
460
F51.0
ICD-10 Finland
Nonorganic insomnia
2.1
19.3
210
1088
J20
ICD-10 Finland
Acute bronchitis
2.2
19.3
183
900
B01AF02
ATC
apixaban; oral
1.8
19.3
372
2328
W19
ICD-10 Finland
Unspecified fall
2.0
19.2
216
1133
I63
ICD-10 Finland
Cerebral infarction
46.6
19.2
23
5
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.5
19.2
66
193
J45
ICD-10 Finland
Asthma
2.1
19.0
184
912
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
+∞
18.8
18
*
F05.1
ICD-10 Finland
Delirium superimposed on dementia
4.9
18.8
41
85
N01
ICPC
Headache
2.3
18.7
144
649
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
7.4
18.7
27
37
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
24.0
18.7
26
11
I63.8
ICD-10 Finland
Other cerebral infarction
101.2
18.6
20
*
N03AX14
ATC
levetiracetam; systemic
4.0
18.5
52
132
G44.2
ICD-10 Finland
Tension-type headache
2.1
18.5
196
1006
SPAT1053
SPAT
Memory test
1.7
18.4
437
2893
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
18.3
286
1677
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.0
18.0
212
1131
I25
ICD-10 Finland
Chronic ischaemic heart disease
2.3
17.9
149
694
N06AB04
ATC
citalopram; systemic
1.8
17.9
330
2033
SPAT1342
SPAT
Referral to specialised care
4.8
17.8
40
85
315
Kela drug reimbursment
Clopidogrel
5.7
17.8
33
59
I67.4
ICD-10 Finland
Hypertensive encephalopathy
+∞
17.7
17
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
17.7
412
2709
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.3
17.6
138
627
R20.2
ICD-10 Finland
Paraesthesia of skin
2.6
17.5
102
404
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
2.5
17.5
115
483
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
17.5
322
1982
G45
ICD-10 Finland
Transient cerebral ischaemic attacks and related syndromes
5.9
17.5
31
53
R26.2
ICD-10 Finland
Difficulty in walking, not elsewhere classified
4.3
17.5
45
107
R83
ICPC
Respiratory infection other
1.9
17.3
228
1263
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.8
17.2
87
320
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.0
17.2
79
276
F00
ICD-10 Finland
Dementia in Alzheimer disease
7.6
17.0
24
32
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.4
17.0
115
490
SPAT1097
SPAT
Recording of ECG
0.4
16.8
86
2030
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
16.8
337
2123
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
0.5
16.7
242
3947
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.5
16.6
40
90
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.7
16.6
94
367
ZXC20
NOMESCO Finland
Use of chemical agents
3.1
16.6
70
233
Z20.8
ICD-10 Finland
Contact with and exposure to other communicable diseases
3.3
16.5
62
192
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
16.5
546
3912
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.4
16.4
115
497
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.3
16.4
132
607
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.1
16.4
172
879
ZXD05
NOMESCO Finland
Urgent procedure
1.6
16.3
491
3436
207
Kela drug reimbursment
Chronic arrhythmias
1.6
16.2
434
2949
SPAT1249
SPAT
Treatment-related counselling outside office
0.6
16.2
321
4812
R5130, ,
SPAT
7.1
16.1
24
34
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
48.0
16.0
19
*
D07AB08
ATC
desonide; topical
2.0
16.0
191
1022
N05BA01
ATC
diazepam; systemic, rectal
1.9
15.9
233
1335
R25.1
ICD-10 Finland
Tremor, unspecified
2.8
15.9
78
283
R49.03
ICD-10 Finland
Atrophic dysphonia
4.0
15.8
44
111
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
6.7
15.8
25
38
R52.0
ICD-10 Finland
Acute pain
3.2
15.7
63
203
Z01.2
ICD-10 Finland
Dental examination
1.6
15.7
567
4134
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
15.6
15
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
15.6
15
*
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
0.5
15.6
174
3080
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.3
15.5
128
594
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.9
15.5
229
1314
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
0.6
15.5
265
4141
EBA30, ,
SPAT
12.5
15.4
27
22
S16
ICPC
Bruise/contusion
2.6
15.3
87
340
M03BC51
ATC
orphenadrine, combinations; systemic
1.7
15.3
360
2361
A08
ICPC
Swelling
2.1
15.3
159
808
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
11.4
15.3
28
25
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.3
15.3
57
176
S09.9
ICD-10 Finland
Unspecified injury of head
3.5
15.2
51
147
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
15.1
229
1324
D19
ICPC
Teeth/gum symptom/complaint
1.7
15.1
363
2395
N03AX16
ATC
[U] pregabalin
1.6
15.1
392
2638
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.7
15.0
283
1748
N05AH03
ATC
olanzapine; systemic
2.6
15.0
89
356
RS222, ,
NOMESCO Finland
4.5
15.0
36
81
R06.0
ICD-10 Finland
Dyspnoea
1.6
15.0
546
3980
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.0
15.0
177
943
QAE99, ,
SPAT
4.2
14.9
39
94
M79.1
ICD-10 Finland
Myalgia
1.9
14.8
212
1204
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
5.4
14.7
29
55
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
14.6
687
5286
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
2.2
14.6
121
563
N06AX21
ATC
duloxetine; oral
1.9
14.5
181
982
R51
ICD-10 Finland
Headache
2.8
14.5
74
274
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
14.4
259
1575
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
3.3
14.4
55
172
F38
ICPC
Eye, Other laboratory test NEC
3.4
14.3
51
153
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
14.3
391
2660
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
14.2
817
6544
R73
ICD-10 Finland
Elevated blood glucose level
2.9
14.1
68
244
K08.3
ICD-10 Finland
Retained dental root
2.1
14.1
145
734
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
14.1
175
948
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.7
14.1
76
290
N03AF02
ATC
oxcarbazepine; oral
3.5
14.1
48
140
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
14.0
259
1587
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
5.5
14.0
27
50
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
5.5
14.0
27
50
R07.0
ICD-10 Finland
Pain in throat
2.6
14.0
85
344
H02AB07
ATC
prednisone; oral
1.8
13.9
257
1575
S22.3
ICD-10 Finland
Fracture of rib
2.1
13.8
139
698
Z51.88
ICD-10 Finland
Other specified medical care
3.0
13.7
60
204
E78
ICD-10 Finland
Disorders of lipoprotein metabolism and other lipidaemias
2.5
13.7
83
336
TNG34
NOMESCO Finland
Major custom moulded orthopaedic cast, knee or lower leg
4.4
13.6
34
79
I50
ICD-10 Finland
Heart failure
2.2
13.6
111
513
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.2
13.5
117
554
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.7
13.4
72
274
K59.1
ICD-10 Finland
Functional diarrhoea
2.2
13.4
117
556
WX402
NOMESCO Finland
General anaesthesia
1.7
13.3
290
1859
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
13.3
479
3465
Z04
ICD-10 Finland
Examination and observation for other reasons
3.7
13.2
41
112
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
13.2
306
1992
R47.0
ICD-10 Finland
Dysphasia and aphasia
5.8
13.2
24
42
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
13.2
215
1269
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
4.3
13.2
34
81
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
13.1
146
762
K02.1
ICD-10 Finland
Caries of dentine
1.5
13.0
686
5364
-44
ICPC
Preventive immunization/medic
0.3
13.0
34
1119
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
12.9
774
6205
K59.0
ICD-10 Finland
Constipation
2.0
12.9
138
709
XF606
NOMESCO Finland
Ortostatic test
4.4
12.9
32
74
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
12.9
277
1768
SPAT1304
SPAT
Counselling and guidance related to ageing
0.4
12.8
62
1509
I67.2
ICD-10 Finland
Cerebral atherosclerosis
14.2
12.8
21
15
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
12.7
272
1734
N05BA04
ATC
oxazepam; oral
1.5
12.7
451
3247
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.7
12.7
39
106
C09CA01
ATC
losartan; oral
1.5
12.7
500
3682
H81.3
ICD-10 Finland
Other peripheral vertigo
2.7
12.6
68
259
H02BX01
ATC
methylprednisolone, combinations; systemic
2.0
12.6
132
672
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
4.3
12.5
32
76
R2110
NOMESCO Finland
Giving the first information
2.3
12.5
98
446
XX9CW
NOMESCO Finland
Submitting image material and/or investigation material to patient
5.7
12.4
23
41
S00
ICD-10 Finland
Superficial injury of head
5.7
12.4
23
41
WX720
NOMESCO Finland
Own respiration
0.1
12.4
*
395
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.7
12.4
224
1363
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.1
12.3
121
602
A11
ICPC
Chest pain NOS
1.8
12.3
187
1081
U07.2
ICD-10 Finland
COVID-19, virus not identified
2.2
12.3
100
462
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.1
12.3
124
624
SPAT1260
SPAT
Consultation of another employee
0.5
12.2
111
2122
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
12.2
174
985
Z76
ICD-10 Finland
Persons encountering health services in other circumstances
4.5
12.2
29
65
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.4
12.1
81
343
K02.0
ICD-10 Finland
Caries limited to enamel
1.8
12.1
183
1055
M19
ICD-10 Finland
Other arthrosis
2.9
12.1
58
208
A02BC05
ATC
esomeprazole; systemic
1.5
12.1
622
4824
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
12.0
529
3976
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
3.2
12.0
47
150
Z26.9
ICD-10 Finland
Need for immunization against unspecified infectious disease
3.9
11.9
35
92
ZA1.0
ICD-10 Finland
Shoulder region
2.9
11.9
54
188
S01
ICD-10 Finland
Open wound of head
4.0
11.8
33
84
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
16.5
11.7
18
11
SPAT1043
SPAT
Audiometry
0.4
11.6
68
1531
L08
ICD-10 Finland
Other local infections of skin and subcutaneous tissue
3.9
11.6
33
85
SPAT1236
SPAT
Informing family of child’s disability
3.0
11.6
52
180
I84
ICD-10 Finland
Hemorrhoids
2.7
11.5
63
242
D01
ICPC
Abdominal pain/cramps general
1.8
11.5
185
1086
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
11.5
308
2072
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.6
11.5
203
3190
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
+∞
11.5
11
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
11.5
11
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.2
11.4
95
443
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
11.4
129
676
R07.3
ICD-10 Finland
Other chest pain
1.8
11.3
185
1093
L60.8
ICD-10 Finland
Other nail disorders
4.8
11.2
25
53
Z13.5
ICD-10 Finland
Special screening examination for eye and ear disorders
4.8
11.2
25
53
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.5
11.1
70
289
D64.8
ICD-10 Finland
Other specified anaemias
2.8
11.0
54
196
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.8
11.0
20
35
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.7
11.0
234
1486
W10
ICD-10 Finland
Fall on and from stairs and steps
2.2
10.9
97
464
N06AB06
ATC
sertraline; oral
2.0
10.9
130
693
K43
ICPC
Cardiovascular, Other diagnostic procedure
3.5
10.9
37
108
S00.0
ICD-10 Finland
Superficial injury of scalp
2.6
10.8
63
250
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.7
10.8
34
94
R52.2
ICD-10 Finland
Other chronic pain
2.5
10.8
68
281
R06AE07
ATC
cetirizine; oral
1.4
10.7
572
4440
Z00.8
ICD-10 Finland
Other general examinations
1.9
10.7
130
699
R39.1
ICD-10 Finland
Other difficulties with micturition
2.5
10.7
66
270
SPAT1222
SPAT
Counselling/guidance promoting independent living
0.6
10.7
152
2537
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.6
10.6
284
1908
J01CA04
ATC
amoxicillin; systemic
1.5
10.6
1157
10208
ZY010
NOMESCO Finland
Hospital outpatient
2.7
10.6
56
212
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
10.5
348
2453
L82
ICD-10 Finland
Seborrhoeic keratosis
1.6
10.5
324
2249
M81.5
ICD-10 Finland
Idiopathic osteoporosis
3.8
10.5
31
82
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
10.4
698
5636
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
110.7
10.4
11
*
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
+∞
10.4
10
*
UJH02
NOMESCO Finland
Anoscopy
2.3
10.4
77
342
A01
ICPC
Pain general/multiple sites
1.7
10.4
194
1189
G04CA02
ATC
tamsulosin; oral
1.5
10.4
457
3416
RD211, ,
NOMESCO Finland
0.1
10.4
*
344
Z25.1
ICD-10 Finland
Need for immunization against influenza
2.2
10.4
91
434
M48.0
ICD-10 Finland
Spinal stenosis
1.6
10.3
274
1836
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
10.3
633
5031
J02AC01
ATC
fluconazole; systemic
1.5
10.3
466
3501
S18
ICPC
Laceration/cut
1.4
10.3
777
6404
G81.9
ICD-10 Finland
Hemiplegia, unspecified
8.8
10.3
21
24
W06
ICD-10 Finland
Fall involving bed
3.7
10.3
32
88
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.3
10.3
77
344
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.6
10.2
227
1456
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.9
10.2
132
724
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
3.4
10.2
36
108
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
10.2
157
911
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.3
10.1
75
333
R35
ICD-10 Finland
Polyuria
1.8
10.1
142
800
D07AA02
ATC
hydrocortisone; topical
1.7
10.1
196
1215
IAB14
NOMESCO Finland
Geriatric psychiatry consultation
11.4
10.1
18
16
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
10.1
215
1366
WX725
NOMESCO Finland
Noninvasive ventilation
0.2
10.0
8
447
1LA05, ,
NOMESCO Finland
4.5
10.0
24
54
130
Kela drug reimbursment
Malignant tumour
0.4
10.0
49
1191
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
10.1
10.0
19
19
N30.9
ICD-10 Finland
Cystitis, unspecified
1.8
10.0
140
789
KMAK, ,
NOMESCO Finland
1.4
9.9
596
4712
C09AA05
ATC
ramipril; oral
1.4
9.9
501
3840
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
9.9
230
1493
R11
ICD-10 Finland
Nausea and vomiting
1.8
9.9
167
995
L29.9
ICD-10 Finland
Pruritus, unspecified
2.6
9.8
56
221
I83
ICD-10 Finland
Varicose veins of lower extremities
2.8
9.8
48
175
X57
ICD-10 Finland
Unspecified privation
2.8
9.8
48
175
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.9
9.8
117
626
M54.8
ICD-10 Finland
Other dorsalgia
2.3
9.7
75
339
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.6
9.7
218
1401
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.2
9.7
77
352
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
9.7
866
7314
B01AB05
ATC
enoxaparin; parenteral
1.4
9.7
552
4317
M15
ICD-10 Finland
Polyarthrosis
1.9
9.7
128
707
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
9.7
324
2286
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
13.5
9.7
16
12
FM1DE, ,
SPAT
5.3
9.6
19
36
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
2.9
9.6
44
154
R32
ICD-10 Finland
Unspecified urinary incontinence
2.3
9.6
71
315
F32.0
ICD-10 Finland
Mild depressive episode
3.2
9.6
37
117
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
9.6
121
658
U02
ICPC
Urinary frequency/urgency
1.6
9.6
276
1883
I48.2
ICD-10 Finland
Chronic atrial fibrillation
1.9
9.6
127
703
EBA00
NOMESCO Finland
Extraction of tooth
1.4
9.5
465
3534
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.1
9.5
86
415
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.6
9.5
31
88
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
15.1
9.5
15
10
X58
ICD-10 Finland
Exposure to other specified factors
1.7
9.5
176
1077
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.0
9.5
100
512
R4150
NOMESCO Finland
Neuropsychological rehabilitation
100.6
9.4
10
*
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
17.6
9.4
14
8
R13
ICD-10 Finland
Dysphagia
1.9
9.4
130
729
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.7
9.4
191
1197
G04BD08
ATC
solifenacin; oral
1.8
9.4
150
879
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.0
9.4
109
577
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
+∞
9.4
9
*
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
9.4
9
*
G46.7*I67.9
ICD-10 Finland
Other lacunar syndromes
+∞
9.4
9
*
HMAK, ,
NOMESCO Finland
0.3
9.4
25
814
QBE99, ,
SPAT
4.7
9.3
21
45
R26
ICD-10 Finland
Abnormalities of gait and mobility
10.7
9.3
17
16
F05.8
ICD-10 Finland
Other delirium
3.7
9.3
29
80
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
9.3
247
1655
S20.2
ICD-10 Finland
Contusion of thorax
2.1
9.3
89
440
UJF32
NOMESCO Finland
Coloscopy
1.4
9.3
462
3523
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.6
9.2
51
198
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
3.2
9.2
35
110
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
9.2
860
7294
N03AX09
ATC
lamotrigine; oral
3.1
9.2
38
126
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.9
9.2
118
647
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
9.1
152
901
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.5
9.1
57
235
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
9.1
432
3263
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
9.1
249
1680
XCK00
NOMESCO Finland
Perimetry
1.8
9.1
133
760
H53.4
ICD-10 Finland
Visual field defects
3.3
9.1
33
101
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
9.0
204
1313
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
9.0
170
1044
XKD00
NOMESCO Finland
Uroflowmetry
1.5
9.0
303
2137
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.4
9.0
63
274
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
9.0
569
4522
DAX08
NOMESCO Finland
Fitting of hearing aid
0.4
8.9
34
926
J01MA02
ATC
ciprofloxacin; systemic
1.4
8.9
651
5292
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
2.6
8.9
51
201
F29
ICPC
Eye symptom/complaint other
1.7
8.9
155
930
C03CA01
ATC
furosemide; systemic
1.4
8.9
778
6512
XCD20
NOMESCO Finland
Photoangiography of eye
2.7
8.9
47
178
F45.8
ICD-10 Finland
Other somatoform disorders
2.7
8.9
48
184
E0000UV, ,
ATC
1.4
8.9
608
4891
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
4.0
8.9
25
64
K30
ICD-10 Finland
Functional dyspepsia
1.7
8.9
161
979
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
2.5
8.9
53
214
B35.6
ICD-10 Finland
Tinea inguinalis [Tinea cruris]
3.1
8.8
36
118
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.0
8.8
91
462
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
8.8
115
633
G03DA02
ATC
medroxyprogesterone; systemic
1.7
8.8
151
903
B01AB04
ATC
dalteparin; parenteral
2.0
8.8
99
519
Z29.8
ICD-10 Finland
Other specified prophylactic measures
3.0
8.8
37
124
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
8.7
505
3945
C10AA07
ATC
rosuvastatin; oral
1.4
8.7
467
3599
K44
ICD-10 Finland
Diaphragmatic hernia
3.9
8.7
25
65
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
8.7
532
4197
R25.2
ICD-10 Finland
Cramp and spasm
2.7
8.7
45
169
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.5
8.7
307
2187
M02AA07
ATC
piroxicam; topical
1.4
8.7
620
5019
M03BX02
ATC
tizanidine; oral
1.4
8.6
717
5944
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
8.6
167
1033
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.5
8.6
55
229
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
4.6
8.6
20
44
UJD10, ,
SPAT
2.7
8.6
46
176
P01AB01
ATC
metronidazole; oral, rectal
1.4
8.5
527
4161
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
2.8
8.5
41
148
SPAT1148
SPAT
Treatment of chronic ulcer or burn
0.6
8.5
121
2030
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
0.5
8.5
96
1721
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
8.5
130
753
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
8.4
528
4176
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
2.9
8.4
39
138
Z29.9
ICD-10 Finland
Prophylactic measure, unspecified
4.5
8.4
20
45
S29
ICPC
Skin symptom/complaint other
1.5
8.4
336
2454
TQW99
NOMESCO Finland
Other minor procedure on skin
1.8
8.3
116
653
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
8.3
399
3014
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.1
8.3
80
397
F32.1
ICD-10 Finland
Moderate depressive episode
2.7
8.3
43
162
G45.3
ICD-10 Finland
Amaurosis fugax
2.8
8.3
40
145
F51
ICD-10 Finland
Nonorganic sleep disorders
2.8
8.2
41
151
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
8.2
228
1541
EB1HA, ,
SPAT
2.8
8.2
39
140
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.2
8.2
66
305
B35.1
ICD-10 Finland
Tinea unguium
1.9
8.1
98
527
B01AC07
ATC
dipyridamole; systemic
2.0
8.0
89
464
A99
ICPC
Disease/condition unspecnature/site
1.6
8.0
188
1221
U04
ICPC
Incontinence urine
1.7
8.0
152
935
PD5BD
NOMESCO Finland
Extensive CT of aorta
2.6
8.0
43
165
C09DA01
ATC
losartan and diuretics; oral
1.6
8.0
194
1271
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.0
540
4319
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
0.5
8.0
56
1178
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.4
7.9
28
84
Y94.8
ICD-10 Finland
Other leisure activity accident
2.5
7.9
49
201
R23.3
ICD-10 Finland
Spontaneous ecchymoses
2.5
7.9
48
195
H25.8
ICD-10 Finland
Other senile cataract
0.6
7.9
137
2187
L60.0
ICD-10 Finland
Ingrowing nail
2.1
7.9
76
376
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.2
7.9
65
303
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
2.6
7.9
43
166
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.0
7.9
83
425
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
3.3
7.8
28
85
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.2
7.8
66
311
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
7.8
9
401
L02
ICPC
Back symptom/complaint
1.7
7.7
133
796
A46
ICD-10 Finland
Erysipelas
1.5
7.7
276
1966
TNH32
NOMESCO Finland
Custom moulded split, ankle or foot
4.2
7.7
20
48
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
4.2
7.7
20
48
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
45.2
7.7
9
*
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.4
7.7
49
204
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
3.9
7.7
22
57
L03
ICPC
Low back symptom/complaint
1.4
7.7
408
3130
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.3
7.7
58
261
R02
ICPC
Shortness of breath/dyspnoea
1.5
7.7
255
1791
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.2
7.7
60
274
N05CF01
ATC
zopiclone; oral
1.4
7.7
551
4443
R21
ICPC
Throat symptom/complaint
1.6
7.7
186
1218
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
7.6
253
1776
R05FB02
ATC
cough suppressants and expectorants; systemic
1.4
7.6
608
4981
I11
ICD-10 Finland
Hypertensive heart disease
3.6
7.6
24
67
XCH05
NOMESCO Finland
Eye pressure longterm registration
3.1
7.6
30
97
FP1C5
NOMESCO Finland
Resting ECG, 15 leads
3.1
7.6
30
97
WX290
NOMESCO Finland
Other blockage of nerve
1.4
7.6
420
3246
TQW40
NOMESCO Finland
Remowal of suture of skin
1.8
7.6
109
620
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
6.2
7.5
19
31
UJF30, ,
SPAT
4.1
7.5
20
49
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
7.5
125
741
UDC00
NOMESCO Finland
Ear microscopy
0.4
7.5
28
769
EB4VA, ,
NOMESCO Finland
0.4
7.5
28
769
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
7.5
69
336
J01CF05
ATC
flucloxacillin; systemic
1.8
7.5
104
584
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.5
196
1306
J01FA10
ATC
azithromycin; systemic
1.3
7.5
639
5285
S01KA02
ATC
hypromellose; ophthalmic
2.5
7.4
45
183
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
0.5
7.4
87
1547
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
2.3
7.4
54
239
H91.9
ICD-10 Finland
Hearing loss, unspecified
1.8
7.4
103
579
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.8
7.4
36
131
N06AX16
ATC
venlafaxine; oral
1.7
7.4
139
853
C07AA05
ATC
propranolol; systemic
1.5
7.4
226
1560
N06AX03
ATC
mianserin; oral
2.0
7.3
80
415
A91
ICPC
Abnormal result investigation NOS
1.9
7.3
97
537
J01EA01
ATC
trimethoprim; systemic
1.4
7.3
460
3625
DFF15
NOMESCO Finland
Speech audiometry
0.3
7.3
23
686
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
8.4
7.3
15
18
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
7.3
122
725
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
+∞
7.3
7
*
SFA30
NOMESCO Finland
Three-surface restoration
1.4
7.3
481
3820
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
0.6
7.3
125
2001
G21.8
ICD-10 Finland
Other secondary parkinsonism
9.4
7.3
14
15
H53.8
ICD-10 Finland
Other visual disturbances
3.3
7.3
27
84
WX213
NOMESCO Finland
Lower leg blockade
3.9
7.3
21
55
EB1VA, ,
NOMESCO Finland
0.5
7.2
61
1204
R06AX27
ATC
desloratadine; oral
1.5
7.2
274
1974
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
2.6
7.2
40
156
SPAT1325
SPAT
Vaccination
0.7
7.2
425
5325
A10AE04
ATC
insulin glargine; parenteral
1.6
7.2
161
1033
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
3.7
7.2
22
60
D09
ICPC
Nausea
2.1
7.2
65
315
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
30.1
7.1
9
*
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
30.1
7.1
9
*
SPAT1370
SPAT
Other health check-up
0.2
7.1
8
364
ZQZ00
NOMESCO Finland
Treatment of several skin areas
3.6
7.0
22
61
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.8
7.0
109
634
H02AB02
ATC
dexamethasone; systemic
0.5
7.0
59
1164
N06AB03
ATC
fluoxetine; oral
1.6
7.0
152
970
U01
ICPC
Dysuria/painful urination
1.7
6.9
136
844
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
6.9
252
1800
I25.8
ICD-10 Finland
Other forms of chronic ischaemic heart disease
2.6
6.9
37
142
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.5
6.9
191
1289
F01.8
ICD-10 Finland
Other vascular dementia
13.8
6.9
11
8
K03.64
ICD-10 Finland
Dental calculus supragingival
1.4
6.9
322
2412
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
6.9
339
2563
U71
ICPC
Cystitis/urinary infection other
1.7
6.9
122
738
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
6.8
56
261
R23
ICD-10 Finland
Other skin changes
3.4
6.8
24
72
R12
ICD-10 Finland
Heartburn
1.7
6.8
114
678
J01FA06
ATC
roxithromycin; oral
1.3
6.8
579
4769
G04BD07
ATC
tolterodine; oral
1.7
6.8
115
686
SDA03
NOMESCO Finland
Periodontal treatment
1.4
6.8
421
3305
L01BC06
ATC
capecitabine; oral
0.2
6.8
9
370
IGY99
NOMESCO Finland
Other psychiatric treatment contact
5.7
6.8
18
32
B60
ICPC
Blood and Immunity, Result test/procedure
2.8
6.8
32
115
TNH31
NOMESCO Finland
Prefabricated orthosis, ankle or foot
4.3
6.8
17
40
G45.8
ICD-10 Finland
Other transient cerebral ischaemic attacks and related syndromes
4.3
6.8
17
40
S70.0
ICD-10 Finland
Contusion of hip
1.8
6.7
91
508
P99
ICPC
Psychological disorders other
3.2
6.7
26
83
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
3.2
6.7
25
78
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.5
6.7
40
162
ZX080
NOMESCO Finland
Image guided radiotherapy
0.0
6.7
*
166
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
6.7
103
598
R30.0
ICD-10 Finland
Dysuria
2.0
6.7
66
331
M01AB05
ATC
diclofenac; systemic, rectal
1.3
6.7
870
7600
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.7
6.7
35
133
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.7
6.7
35
133
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
0.6
6.7
162
2392
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.6
6.6
37
145
G30
ICD-10 Finland
Alzheimer disease
2.3
6.6
46
200
R49.0
ICD-10 Finland
Dysphonia
2.7
6.6
33
122
N02AX02
ATC
tramadol; systemic, rectal
1.3
6.6
653
5488
H92.0
ICD-10 Finland
Otalgia
2.0
6.6
72
374
H53.2
ICD-10 Finland
Diplopia
2.2
6.6
51
232
ZY000
NOMESCO Finland
Hospital inpatient
5.5
6.6
18
33
L12
ICPC
Hand/finger symptom/complaint
1.5
6.6
230
1629
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.2
6.6
56
265
R54
ICD-10 Finland
Senility
3.6
6.6
21
59
H61.2
ICD-10 Finland
Impacted cerumen
1.7
6.6
119
723
R01AD09
ATC
mometasone; nasal
1.3
6.6
511
4150
62550, ,
ICD-8 Finland
4.2
6.6
17
41
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.8
6.5
97
557
P29
ICPC
Psychological sympt/compl other
2.1
6.5
56
266
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
3.8
6.5
19
50
5CM18, ,
NOMESCO Finland
10.1
6.5
12
12
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
1.7
6.5
123
756
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
6.9
6.5
15
22
Z02
ICD-10 Finland
Examination and encounter for administrative purposes
6.9
6.5
15
22
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
6.5
346
2648
H60
ICD-10 Finland
Otitis externa
2.1
6.5
56
267
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
0.3
6.5
16
540
B02
ICD-10 Finland
Zoster [herpes zoster]
1.9
6.5
80
434
R33
ICD-10 Finland
Retention of urine
1.6
6.5
170
1134
K05.31
ICD-10 Finland
Periodontitis pronounced
1.6
6.5
147
948
ZXE22
NOMESCO Finland
Procedure duration at least 4 but less than 5 hours
70.1
6.4
7
*
F01.84
ICD-10 Finland
Other specified vascular dementia other mixed symptoms of mixed type
70.1
6.4
7
*
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.3
6.4
48
216
S42.2
ICD-10 Finland
Fracture of upper end of humerus
1.8
6.4
100
584
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.0
6.4
67
344
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.4
623
5222
Z5132
NOMESCO Finland
Nursing associate professional
3.8
6.4
19
51
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.4
6.3
41
173
G40
ICD-10 Finland
Epilepsy
6.0
6.3
16
27
F01
ICD-10 Finland
Vascular dementia
5.5
6.3
17
31
N28
ICPC
Limited function/disability (N)
2.6
6.3
36
143
C10AA04
ATC
fluvastatin; oral
1.5
6.3
192
1323
R03BA02
ATC
budesonide; inhalant
1.5
6.3
244
1764
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
0.1
6.3
*
212
N30.8
ICD-10 Finland
Other cystitis
3.3
6.3
23
71
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
3.4
6.3
22
66
N05AN01
ATC
lithium; oral
3.4
6.3
22
66
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.3
263
1929
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.7
6.3
111
671
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
+∞
6.3
6
*
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
3.0
6.2
26
87
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.7
6.2
111
672
H26.9
ICD-10 Finland
Cataract, unspecified
2.6
6.2
35
138
N43
ICPC
Neurological, Other diagnostic procedure
5.0
6.2
18
36
G25.2
ICD-10 Finland
Other specified forms of tremor
4.0
6.2
17
43
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
2.4
6.2
41
175
R31
ICD-10 Finland
Unspecified haematuria
1.5
6.2
198
1379
F32.8
ICD-10 Finland
Other depressive episodes
3.4
6.1
21
62
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.8
6.1
16
28
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
7.7
6.1
13
17
S20
ICD-10 Finland
Superficial injury of thorax
7.7
6.1
13
17
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.7
6.1
119
738
SPAT1305
SPAT
Counselling and guidance related to physical exercise
0.5
6.1
65
1188
L03
ICD-10 Finland
Cellulitis
3.8
6.1
18
48
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.8
6.1
18
48
-31
ICPC
Medical examin/health eval partial
0.4
6.1
35
794
R03AC02
ATC
salbutamol; inhalant
1.3
6.1
735
6326
SPAT1254
SPAT
Administration of medicine
0.6
6.1
152
2234
NF3AA
NOMESCO Finland
Femur X-ray examination
2.2
6.1
50
234
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
6.1
129
818
ZXC10
NOMESCO Finland
Use of laser
2.4
6.1
39
164
G20
ICD-10 Finland
Parkinson disease
1.9
6.1
73
393
F43
ICPC
Eye, Other diagnostic procedure
2.5
6.0
35
140
J01MA06
ATC
norfloxacin; oral
1.5
6.0
216
1538
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
2.8
6.0
28
100
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.8
6.0
28
100
M05BA04
ATC
alendronic acid; oral
1.5
6.0
216
1539
H26.4
ICD-10 Finland
After-cataract
1.4
6.0
267
1979

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
893
2682
6.18
297.63
3.8
3.3
3.26
2.76
e6/l
0.50
343
1394
1020
3504
6.14
289.44
4.7
4.0
79.68
82.72
%
3.20
1011
3420
920
2925
5.95
284.57
3.7
3.2
1.35
1.28
e6/l
0.14
377
1644
1041
3751
5.95
275.85
3.3
3.0
2.48
2.48
mmol/l
0.12
942
3344
1070
4367
5.26
231.54
4.4
3.5
0.49
400.20
estimate
—
9
32
1094
4693
5.08
217.88
4.4
3.5
0.59
0.53
e6/l
0.24
678
3581
1217
5932
5.20
198.37
6.0
4.2
107.65
146.19
e6/l
0.62
744
4391
1139
5439
4.67
186.33
4.5
3.6
46.48
91.53
e6/l
2.65
740
4282
1152
5849
4.34
165.32
3.0
3.4
2.37
2.36
mmol/l
4.54
1071
5215
1337
7690
5.19
158.21
3.5
2.3
92.55
94.15
pmol/l
0.70
736
3929
1087
5486
3.97
152.78
2.2
1.8
19.52
20.22
nmol/l
0.91
1022
4540
803
3337
3.78
151.56
4.8
4.5
220.50
276.13
ng/l
0.36
780
3000
471
1367
4.45
148.22
2.4
2.4
32.19
39.46
u/l
2.33
395
1120
842
3774
3.56
138.13
3.8
3.7
0.00
0.06
1.92
16
166
1028
5220
3.64
138.09
3.5
4.0
7.40
7.40
ph
1.96
553
3813
1269
7509
4.16
131.84
4.7
4.6
34.97
34.28
g/l
4.85
1207
6958
474
1507
4.03
129.92
6.0
6.5
—
—
—
0
0
479
1589
3.86
122.74
5.4
5.6
1.40
1.38
mmol/l
0.15
470
1551
547
2142
3.34
106.39
2.1
1.8
29.86
30.09
s
0.40
539
2053
1200
7608
3.21
95.05
6.4
6.1
1.21
1.21
mmol/l
1.33
1156
6933
1409
9871
4.24
94.24
40.6
26.0
14.07
14.10
%
0.33
1403
9733
1093
6717
2.92
88.90
2.5
2.4
78.44
81.77
nmol/l
3.45
1011
5794
841
4602
2.72
84.37
2.4
2.0
282.84
233.78
u/l
0.66
801
4276
167
332
5.49
80.87
1.5
1.8
21.62
21.72
s
0.05
157
302
1345
9517
3.41
80.13
5.4
5.0
—
0.37
—
0
27
315
1031
3.55
79.32
6.6
7.0
24.24
24.39
mmol/l
0.35
305
995
984
5947
2.66
78.77
8.6
13.0
0.00
0.00
e9/l
0.90
639
4822
1245
8599
2.92
74.08
6.5
6.9
1.21
1.21
mmol/l
0.00
1188
7322
300
1010
3.42
71.81
2.7
3.2
24.13
24.06
mmol/l
0.11
291
995
1270
8985
2.90
69.81
5.4
4.8
6.76
6.90
mmol/l
1.57
1220
8575
396
1626
2.90
67.00
2.2
2.5
8.50
10.26
umol/l
0.76
343
1419
688
3710
2.48
66.94
1.6
1.8
891.59
1185.22
nmol/l
14.20
495
2745
973
6141
2.46
66.50
4.2
4.1
6.47
6.32
ph
1.91
247
3304
824
4882
2.40
64.19
5.2
5.6
—
—
—
0
0
290
1024
3.23
63.74
5.9
6.5
24.90
24.89
mmol/l
0.02
290
1016
1494
11830
4.31
63.24
7.0
5.6
1.97
2.12
mu/l
3.73
1447
10553
308
1137
3.11
62.71
7.1
7.2
93.90
93.82
%
0.08
308
1131
678
3735
2.40
61.71
2.4
2.6
—
—
—
0
0
74
83
9.29
60.54
1.2
1.3
—
—
—
0
0
113
207
5.79
59.48
1.2
1.3
3.34
77.93
e6/l
1.19
74
159
813
4907
2.32
59.14
2.5
2.7
—
—
—
0
0
632
3447
2.37
58.04
3.3
3.1
556.01
519.85
mosm/kgh2o
4.54
517
3018
113
212
5.65
57.97
1.2
1.4
82.56
559.47
e6/l
0.76
78
172
942
6089
2.30
57.65
4.3
4.0
—
—
—
0
0
1411
10994
3.17
56.80
7.6
8.0
83.44
83.42
u/l
0.00
1360
10300
1131
7944
2.40
56.26
7.4
8.6
4.53
4.40
e9/l
0.95
820
6765
413
1884
2.60
55.76
2.9
3.2
1.48
1.90
mmol/l
1.26
367
1610
792
4818
2.26
55.42
2.8
2.5
2.39
3.05
mg/l
14.08
693
4102
964
6404
2.24
53.66
6.2
5.8
59.82
59.60
%
0.22
910
6029
416
1949
2.53
52.77
3.0
3.2
5.86
5.84
kpa
0.11
404
1890
835
5263
2.21
52.64
5.5
4.2
—
—
—
0
0
1534
12732
4.74
52.60
30.7
20.6
30.59
28.92
mg/l
1.39
1401
11039
166
465
3.86
51.76
3.7
3.6
2.25
1.85
index
0.33
64
237
411
1951
2.48
50.41
3.0
3.3
7.38
7.38
ph
0.06
189
1169
931
6193
2.18
50.38
3.6
3.1
118.53
147.32
ug/l
3.70
894
5567
962
6484
2.19
50.30
6.2
5.8
2.69
2.78
%
0.62
904
5973
961
6485
2.18
49.96
6.2
5.9
0.63
0.63
%
0.07
901
5977
105
211
5.25
49.87
1.2
1.3
3.93
3.82
mmol/l
0.43
97
195
699
4186
2.18
49.20
6.0
6.4
—
—
—
0
0
960
6502
2.17
49.09
6.2
5.9
9.39
9.24
%
0.78
901
5986
966
6574
2.16
48.58
6.3
5.9
24.08
24.94
%
1.46
911
6136
1295
9933
2.50
48.53
4.4
4.4
14.97
15.34
pmol/l
5.86
1217
8784
1002
6933
2.16
48.04
6.0
5.5
0.66
0.63
e9/l
2.33
706
5738
96
185
5.45
47.75
1.1
1.2
—
—
—
0
0
1004
6963
2.16
47.70
6.0
5.5
0.04
0.04
e9/l
0.03
704
5778
359
1660
2.49
46.17
2.6
2.8
4.34
4.27
kpa
0.32
346
1611
1010
7085
2.13
45.71
6.0
5.6
2.05
1.82
e9/l
0.55
727
6049
1027
7263
2.13
45.31
3.0
3.1
50.60
58.40
u/l
1.93
951
6479
1473
12237
3.20
43.48
6.8
6.2
2.29
2.49
mmol/l
16.20
1404
10833
1009
7150
2.09
43.45
6.2
5.6
0.19
0.19
e9/l
0.15
725
6030
1533
13069
4.12
42.79
14.3
13.0
22.29
22.77
u/l
0.60
1517
12519
414
2115
2.29
42.03
6.2
5.8
7.42
7.42
ph
0.57
107
1208
109
261
4.40
41.88
1.2
1.2
—
—
—
0
0
415
2128
2.28
41.72
6.2
5.7
0.10
1.14
mmol/l
4.97
375
1709
414
2126
2.27
41.44
6.3
5.8
5.07
5.09
kpa
0.15
401
2024
640
3899
2.06
41.18
2.9
2.8
5.31
5.51
e6/l
0.20
551
3557
413
2126
2.26
41.05
6.3
5.8
11.89
11.64
kpa
0.43
400
2027
145
434
3.57
40.81
2.2
2.3
59.19
56.99
%
0.48
133
420
1468
12280
3.05
40.62
5.9
5.9
6.21
6.13
mmol/l
1.28
1386
10801
1546
13359
4.31
39.97
43.2
31.5
4.27
4.29
e12/l
0.88
1512
12924
1546
13359
4.31
39.97
43.3
31.5
236.02
238.61
e9/l
0.84
1510
12992
1546
13362
4.31
39.89
43.1
31.5
7.26
7.04
e9/l
1.18
1512
12923
487
2727
2.12
38.87
2.6
2.6
19.09
20.52
%
1.73
469
2487
1443
12038
2.79
38.68
8.1
7.5
41.35
40.77
mmol/mol
1.26
1393
10889
1080
8064
2.01
37.51
4.4
6.1
13.01
12.63
umol/l
0.38
1032
7646
523
3058
2.05
36.81
1.6
1.6
1.46
1.72
mg/l
1.16
401
2419
1030
7614
1.97
36.20
4.6
4.8
0.00
0.00
estimate
0.50
76
1708
503
2917
2.05
36.09
2.5
2.6
2.15
2.24
g/l
2.95
479
2662
465
2625
2.08
35.86
3.4
3.7
0.76
0.86
ug/l
1.39
381
1939
1043
7785
1.95
35.10
4.6
4.8
0.05
0.19
estimate
0.34
82
1684
463
2645
2.05
34.34
2.4
2.6
0.80
0.82
mmol/l
3.26
414
2439
66
122
5.60
34.29
4.1
3.6
309.49
339.89
umol/l
0.86
61
107
521
3114
1.99
33.97
2.6
2.6
10.28
11.26
umol/l
3.05
495
2845
1267
10192
2.11
33.53
4.3
4.5
15.38
16.07
mm/h
0.82
1201
9265
1032
7742
1.91
33.39
4.6
4.8
0.02
5.26
estimate
1.71
86
1793
185
718
2.78
33.33
2.2
2.5
10.16
10.45
g/l
0.42
159
625
119
360
3.49
32.85
1.2
1.2
—
—
—
0
0
55
92
6.15
31.67
1.1
1.1
—
—
—
0
0
333
1731
2.16
31.38
7.1
6.3
117.82
118.35
g/l
0.19
333
1686
186
751
2.67
30.95
2.2
2.5
3.06
3.03
g/l
0.19
160
666
73
171
4.42
28.80
3.6
3.3
13.44
11.47
index
0.52
32
83
350
1911
2.06
28.73
6.8
5.9
94.97
95.27
%
0.32
345
1838
93
261
3.72
28.70
1.2
1.3
—
—
—
0
0
52
91
5.87
28.61
1.0
1.0
237.77
314.38
ng/l
1.77
40
55
191
813
2.53
28.45
2.2
2.4
3.93
3.80
g/l
0.43
165
730
191
815
2.52
28.30
2.2
2.4
4.06
4.19
g/l
1.48
165
731
52
92
5.81
28.29
1.0
1.0
797.33
621.15
ng/l
1.50
40
54
191
816
2.52
28.23
2.2
2.4
7.56
7.62
g/l
0.18
165
731
156
609
2.73
27.66
2.0
2.1
843.85
595.66
ug/l
0.32
150
575
403
2391
1.91
25.71
2.0
2.4
1.76
1.80
%
0.42
354
2111
65
152
4.41
25.70
1.7
1.5
9.76
9.95
%
0.10
65
152
1381
11874
2.09
24.83
4.7
5.3
4.14
4.40
mmol/l
16.57
1291
10539
1364
11728
2.02
23.72
4.5
5.2
1.42
1.48
mmol/l
5.55
1263
10312
74
203
3.77
23.60
1.1
1.1
—
—
—
0
0
89
289
3.20
21.91
1.6
1.3
0.32
0.27
mg/l
0.48
48
99
871
6667
1.66
21.79
2.7
2.9
—
—
estimate
—
0
0
50
1717
0.27
21.10
7.4
4.7
7.32
7.36
ph
0.50
30
1214
266
1464
1.98
20.78
3.1
3.3
91.54
96.52
ng/l
0.48
237
1201
106
394
2.81
20.57
1.8
1.5
24.24
31.71
u/ml
0.38
12
58
201
1006
2.14
20.31
1.5
1.7
1.61
1.55
g/l
0.41
172
868
223
3911
0.50
20.27
5.7
4.3
0.02
0.63
estimate
1.17
52
1307
348
2116
1.82
19.94
1.4
1.6
2.89
2.77
g/l
0.30
125
1173
302
1784
1.85
18.91
2.6
3.3
295.90
254.44
ng/l
1.11
286
1644
60
169
3.65
18.45
1.0
1.1
—
—
—
0
0
25
1205
0.20
18.15
3.9
4.7
—
—
—
0
0
197
1029
2.04
17.69
2.6
2.3
0.60
0.62
%
0.35
197
1022
184
947
2.06
17.18
1.6
1.6
—
—
—
0
0
400
5723
0.60
16.96
6.0
4.9
0.08
0.42
estimate
0.46
53
1391
723
5506
1.56
16.85
2.4
2.4
—
—
—
0
0
195
1039
2.00
16.53
2.6
2.4
1.19
1.10
%
0.88
195
1032
1287
11237
1.70
16.41
3.8
4.4
1.19
1.23
mmol/l
2.07
1152
9737
62
1658
0.35
15.92
3.2
3.1
4.96
4.87
e9/l
0.05
53
1342
164
841
2.06
15.43
1.2
1.2
—
—
—
0
0
304
1904
1.73
15.36
1.3
1.3
—
—
—
0
0
299
4512
0.59
15.22
5.1
4.8
0.00
0.00
estimate
0.78
66
1534
515
3711
1.57
14.84
4.6
5.4
24.76
22.32
%
2.42
236
2101
25
42
6.03
14.34
1.2
1.2
0.49
0.50
ratio
0.16
17
25
625
4736
1.52
14.17
1.7
1.9
1.26
1.25
mmol/l
0.05
607
3763
965
8002
1.51
14.12
28.7
20.8
1.49
1.40
inr
3.44
740
6786
283
1784
1.71
13.85
1.8
1.8
—
—
—
0
0
187
1043
1.90
13.79
1.5
1.4
—
—
—
0
0
198
3259
0.55
13.62
3.5
3.8
—
—
—
0
0
252
3850
0.59
13.03
1.7
1.8
466.81
7660159.22
pmol/l
1.29
224
3068
516
3809
1.52
12.97
2.6
2.9
362.42
364.64
umol/l
0.17
414
3182
154
2662
0.53
12.38
4.9
4.7
—
—
—
0
0
62
1488
0.39
12.38
2.9
3.6
1.24
1.23
mmol/l
1.19
57
1248
51
1325
0.36
12.17
5.1
4.0
0.45
0.69
%
0.54
11
437
538
4053
1.49
12.08
3.0
2.9
33.15
36.29
u/l
0.71
500
3764
117
583
2.09
11.87
1.3
1.3
—
—
—
0
0
330
2260
1.58
11.44
2.1
1.9
—
—
—
0
0
254
1653
1.64
10.84
2.2
2.6
66.01
65.79
g/l
0.19
223
1472
210
1303
1.70
10.76
1.9
1.9
125.46
169.22
ug/g
1.64
182
1009
153
867
1.84
10.69
1.5
1.4
—
—
—
0
0
32
86
3.78
10.60
1.0
1.1
4.81
2.81
u/ml
0.35
16
43
351
2484
1.53
10.41
1.3
1.2
2.62
1.29
u/ml
0.69
47
595
67
281
2.44
10.28
1.7
2.2
24.62
33.41
umol/l
3.24
52
241
59
1322
0.43
9.91
6.5
4.3
0.00
0.20
%
—
6
369
108
559
2.00
9.90
1.1
1.1
—
2.15
—
0
6
236
1541
1.62
9.90
1.5
1.4
—
—
—
0
0
586
4627
1.42
9.78
5.6
6.6
3.30
5.18
ug/l
0.97
530
4076
771
6396
1.39
9.58
3.1
3.5
2593.15
1991.23
ng/l
1.63
697
5649
68
1400
0.46
9.13
6.0
4.1
0.53
0.84
%
0.97
17
464
63
1334
0.45
9.13
6.3
4.1
0.08
0.13
%
0.20
12
401
308
2186
1.50
8.88
4.8
4.7
1.01
1.05
mmol/l
1.90
276
2008
64
284
2.30
8.71
1.5
1.4
—
—
—
0
0
6
361
0.16
8.44
1.8
4.8
5.05
5.05
kpa
—
6
353
6
362
0.16
8.43
1.8
4.8
9.28
8.19
kpa
—
6
354
82
410
2.05
8.30
11.9
13.7
—
—
—
0
0
80
407
2.02
7.74
1.4
1.4
53.15
58.92
mmol/l
0.90
66
327
88
464
1.95
7.70
1.4
1.5
259.84
266.86
ug/g
0.12
56
292
13
12
10.91
7.30
1.1
1.0
—
—
—
0
0
419
3269
1.38
7.06
1.2
1.3
—
—
—
0
0
149
946
1.63
6.96
2.3
2.6
—
—
—
0
0
262
1887
1.46
6.92
2.0
2.4
66.33
67.18
e9/l
0.14
96
1416
48
209
2.34
6.88
1.2
1.2
33.82
41.19
u/ml
—
5
20
113
682
1.71
6.42
2.7
2.9
4.15
4.30
pmol/l
1.18
98
585
221
1575
1.47
6.14
4.9
5.4
11.26
12.13
mmol/l
0.83
210
1494
150
990
1.57
5.98
1.5
1.4
—
—
—
0
0
21
64
3.31
5.87
2.0
2.1
—
—
—
0
0
5
263
0.19
5.78
3.2
2.8
—
—
—
0
0
114
722
1.62
5.42
2.4
2.8
—
—
—
0
0
109
684
1.64
5.38
1.2
1.2
—
—
—
0
0
35
752
0.45
5.31
3.4
2.1
0.00
0.00
estimate
-0.00
16
201
23
79
2.94
5.31
1.2
1.2
—
—
—
0
0
103
645
1.64
5.13
3.8
3.5
0.72
0.83
nmol/l
1.85
95
522
34
146
2.36
5.10
1.3
1.1
35.60
35.46
mmol/l
0.01
25
127
47
231
2.07
5.09
1.3
1.4
—
—
—
0
0
72
410
1.79
5.06
1.5
1.6
18421.03
17278.06
e6/l
0.06
34
280
257
1953
1.38
4.95
1.5
1.4
—
—
—
0
0
20
66
3.06
4.95
1.3
1.2
—
—
—
0
0
56
300
1.90
4.78
1.2
1.1
—
—
—
0
0
103
658
1.60
4.76
2.0
3.0
209.78
3775.31
u/ml
1.30
82
563
200
1474
1.41
4.62
1.3
1.3
455.38
502.93
titre
0.22
39
368
224
1687
1.38
4.56
1.7
2.6
6.31
5.45
ug/l
0.34
184
1419
21
75
2.82
4.56
1.5
1.4
1641.76
1677.71
ml
0.08
21
70
25
573
0.43
4.53
2.2
3.9
7.40
7.41
ph
1.15
25
565
9
296
0.30
4.51
1.6
3.1
56.11
60.43
%
—
9
296
27
112
2.43
4.40
1.6
1.4
—
—
—
0
0
20
71
2.84
4.39
1.3
1.1
—
—
—
0
0
49
260
1.91
4.34
1.3
1.4
86256.26
76950.68
e6/l
0.04
23
145
46
244
1.91
4.09
1.3
1.5
—
—
—
0
0
71
1107
0.62
3.72
6.1
3.7
7.40
7.41
ph
0.51
59
919
254
2011
1.31
3.71
1.3
1.3
44.36
38.33
iu/ml
0.21
50
633
116
808
1.47
3.67
1.3
1.3
—
—
—
0
0
252
1999
1.31
3.62
2.7
4.0
5.65
24.51
ug/l
2.91
205
1676
12
30
4.02
3.59
1.2
1.5
—
—
—
0
0
17
62
2.76
3.59
1.5
1.4
61.50
100.38
umol/l
—
8
42
50
291
1.74
3.36
1.3
1.4
1826.50
1715.96
e6/l
0.05
24
203
44
247
1.80
3.34
1.3
1.6
—
—
—
0
0
26
122
2.15
3.27
2.0
2.2
513.67
611.47
ml
0.80
21
68
6
7
8.60
3.26
1.0
1.0
—
—
—
0
0
16
60
2.68
3.23
1.0
1.1
164.31
130.87
nmol/l
0.55
16
60
17
66
2.59
3.21
1.5
1.6
—
—
—
0
0
46
763
0.59
3.15
5.2
3.8
—
—
—
0
0
86
1238
0.68
3.12
3.0
3.5
6.12
6.09
ph
0.11
53
936
11
31
3.57
2.99
1.0
1.3
—
13.00
%
—
0
5
27
134
2.03
2.96
1.3
1.2
—
40.84
—
0
7
6
189
0.31
2.81
4.3
3.0
—
—
—
0
0
17
369
0.45
2.79
2.7
3.1
29.05
1518.55
u/ml
1.26
17
335
12
39
3.09
2.77
1.0
1.2
—
54.20
%
—
0
5
116
1549
0.73
2.74
2.5
2.2
0.00
0.00
estimate
-0.00
26
283
36
206
1.76
2.63
1.2
1.2
269.88
272.10
mosm/kgh2o
0.17
17
142
8
20
4.01
2.57
1.4
1.2
—
—
—
0
0
129
989
1.33
2.41
4.5
4.2
1.02
1.02
ratio
0.54
105
908
15
64
2.36
2.39
1.1
1.1
—
—
—
0
0
0
67
0.00
2.39
0.0
1.3
—
520.77
—
0
35
5
8
6.26
2.37
2.4
2.4
18.90
18.14
umol/l
—
5
8
8
23
3.49
2.27
1.0
1.1
—
—
—
0
0
64
441
1.47
2.24
1.6
1.5
1.17
7.11
iu/ml
4.66
11
96
9
211
0.42
2.19
1.6
1.1
—
—
—
0
0
36
575
0.62
2.19
3.0
2.8
466.56
443.05
mg/l
0.05
16
223
62
881
0.69
2.16
1.9
2.2
—
—
—
0
0
158
1270
1.27
2.10
1.7
2.0
431.26
391.93
nmol/l
1.36
138
1152
24
419
0.57
2.08
5.1
3.8
—
—
—
0
0
6
15
4.01
2.04
1.2
1.1
—
—
—
0
0
8
26
3.09
2.01
1.0
1.1
—
—
—
0
0
5
11
4.56
1.94
1.2
1.1
—
—
—
0
0
8
187
0.42
1.93
2.9
4.9
—
—
—
0
0
55
382
1.46
1.89
1.3
1.2
0.39
0.81
u/ml
—
10
29
0
53
0.00
1.87
0.0
2.6
—
1750.81
—
0
43
24
137
1.76
1.83
1.3
1.3
182.90
152.82
au/ml
—
10
37
5
13
3.85
1.71
4.6
3.8
—
—
—
0
0
0
46
0.00
1.71
0.0
5.9
—
24.19
—
0
41
5
130
0.38
1.62
4.4
1.6
226.20
102.94
ng/l
—
5
130
9
186
0.48
1.62
1.2
2.3
—
—
—
0
0
21
349
0.60
1.58
1.1
1.4
—
—
—
0
0
86
667
1.31
1.56
3.6
3.2
5.91
6.80
ratio
0.07
33
406
48
341
1.42
1.52
1.3
1.4
30.58
30.85
g/l
0.05
39
315
213
1835
1.19
1.50
1.3
1.3
12.49
17.34
u/ml
0.30
48
595
93
734
1.28
1.50
3.5
3.3
50.10
82.78
mg/l
0.60
82
628
12
230
0.52
1.49
1.8
2.4
—
—
—
0
0
96
1197
0.79
1.46
7.7
5.5
24.75
24.46
mmol/l
0.27
96
1143
24
148
1.63
1.44
1.3
1.2
279.68
234.93
pmol/l
0.38
19
125
92
735
1.27
1.36
3.5
3.3
67.04
139.78
mg/l
0.47
81
626
444
4832
0.89
1.35
2.4
2.5
60.08
77.06
u/l
0.50
412
4421
0
39
0.00
1.33
0.0
1.2
—
1.32
—
0
23
0
39
0.00
1.33
0.0
1.2
—
—
—
0
0
25
160
1.57
1.32
2.0
1.2
0.19
0.21
nmol/l
0.25
16
130
6
24
2.51
1.30
1.0
2.0
79.17
93.46
nmol/24h
—
6
24
40
284
1.42
1.30
1.6
1.6
5.12
4.27
iu/l
0.20
12
115
8
34
2.36
1.29
1.6
1.2
—
—
—
0
0
5
18
2.78
1.28
2.4
1.4
—
—
—
0
0
184
1592
1.18
1.26
2.1
1.9
0.20
0.19
g/l
2.01
166
1462
8
36
2.23
1.24
1.1
1.1
186.19
140.99
mmol/24h
—
8
36
8
36
2.23
1.24
1.0
1.2
—
—
—
0
0
175
1510
1.18
1.24
1.4
1.3
—
—
—
0
0
8
37
2.17
1.21
2.4
1.8
0.65
0.62
mmol/l
—
8
37
8
37
2.17
1.21
1.0
1.2
—
—
—
0
0
8
37
2.17
1.21
1.0
1.2
—
—
—
0
0
8
37
2.17
1.21
1.0
1.2
—
—
—
0
0
11
57
1.94
1.17
1.1
1.1
—
—
—
0
0
0
33
0.00
1.16
0.0
1.4
—
33.30
—
0
23
0
33
0.00
1.16
0.0
2.2
—
2.62
—
0
12
8
39
2.06
1.15
3.0
1.2
28.13
30.13
umol/l
—
8
34
65
510
1.29
1.15
1.3
1.2
—
—
—
0
0
24
158
1.53
1.15
1.1
1.1
—
—
—
0
0
36
258
1.40
1.14
2.5
2.3
1.20
1.20
mmol/l
0.29
36
253
36
260
1.39
1.10
2.5
2.3
106.97
105.31
mmol/l
0.94
36
255
36
260
1.39
1.10
2.5
2.3
4.00
4.13
mmol/l
1.09
36
255
21
137
1.54
1.06
1.7
1.6
24.02
34.95
ng/l
0.51
21
137
10
53
1.89
1.01
1.1
1.0
—
9.17
—
0
11
9
48
1.88
1.00
1.6
1.3
—
—
—
0
0
9
48
1.88
1.00
1.8
1.1
—
—
—
0
0
24
164
1.47
0.99
1.3
1.3
—
—
—
0
0
7
131
0.53
0.99
1.0
1.2
—
—
—
0
0
0
30
0.00
0.97
0.0
1.1
—
163.30
—
0
30
7
36
1.95
0.97
1.0
1.2
—
—
—
0
0
0
31
0.00
0.96
0.0
2.1
—
0.68
—
0
31
0
31
0.00
0.96
0.0
1.2
—
38.75
—
0
20
48
374
1.29
0.93
2.1
2.3
39.68
80.48
ug/min
1.64
34
207
6
29
2.07
0.89
1.2
1.0
2389.83
1287.52
miu/ml
—
6
29
70
847
0.82
0.89
1.8
1.8
1.29
2.61
ug/l
1.03
59
736
16
104
1.54
0.84
1.1
1.1
—
—
—
0
0
6
113
0.53
0.83
2.7
3.1
—
—
—
0
0
20
138
1.45
0.81
1.2
1.2
250.82
320.78
u/ml
0.56
11
67
107
926
1.17
0.79
2.0
3.1
10.72
10.93
g/l
0.18
100
829
41
321
1.28
0.79
1.4
1.4
—
—
—
0
0
322
3467
0.91
0.79
5.0
5.1
1.02
1.02
kg/l
0.22
199
2360
7
122
0.57
0.78
1.1
1.2
—
—
—
0
0
58
476
1.23
0.77
3.5
3.4
7.84
7.74
mmol/l
0.10
58
463
22
157
1.41
0.76
1.0
1.1
—
—
—
0
0
41
323
1.28
0.76
1.2
1.1
—
684.17
—
0
12
6
34
1.77
0.76
2.0
1.4
0.15
0.13
nmol/l
—
6
23
57
469
1.22
0.74
1.1
1.1
—
137.50
—
0
6
5
25
2.00
0.72
1.2
1.4
—
—
—
0
0
24
178
1.35
0.69
1.3
1.2
—
—
—
0
0
10
61
1.64
0.68
1.0
1.0
—
—
—
0
0
23
171
1.35
0.65
1.0
1.1
—
—
—
0
0
624
6494
0.94
0.64
4.6
4.7
53.76
85.88
ng/l
0.96
422
5286
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
14.50
—
0
10
0
23
0.00
0.58
0.0
6.7
—
4.71
—
0
23
7
113
0.62
0.58
1.7
3.0
7.49
7.19
mmol/l
—
7
76
12
81
1.49
0.57
1.5
1.4
—
—
—
0
0
10
65
1.54
0.55
1.1
1.1
11.92
10.01
mmol/l
—
10
58
8
124
0.64
0.54
1.5
1.9
—
—
—
0
0
9
60
1.50
0.54
1.1
1.0
—
—
—
0
0
25
196
1.28
0.52
1.7
1.9
175.54
2026.80
u/ml
0.67
25
191
61
528
1.16
0.51
4.7
3.4
3.90
3.93
mmol/l
0.13
61
522
135
1478
0.91
0.51
2.5
2.4
0.70
0.60
e6/l
0.18
126
1428
522
5423
0.94
0.49
3.8
4.1
14.48
8.94
mg/mmol
1.08
342
3359
63
550
1.15
0.48
5.7
5.2
—
—
—
0
0
15
199
0.75
0.46
2.1
2.2
0.90
1.15
g/24h
—
6
107
5
82
0.61
0.45
1.2
1.1
—
—
—
0
0
11
77
1.43
0.45
1.1
1.5
—
—
—
0
0
5
85
0.59
0.45
4.6
1.7
1.20
2.28
u/field
—
5
58
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
16
123
1.30
0.40
1.1
1.1
—
30.11
—
0
14
510
5272
0.95
0.40
3.0
3.3
6.45
6.56
mmol/l
0.27
430
4304
13
97
1.34
0.39
2.5
2.8
—
—
—
0
0
0
19
0.00
0.39
0.0
2.7
—
1.47
—
0
19
93
1019
0.91
0.38
1.9
1.5
—
—
—
0
0
63
563
1.12
0.37
1.1
1.1
143.18
113.59
u/ml
0.16
12
190
9
71
1.27
0.36
1.1
1.0
—
—
—
0
0
52
462
1.13
0.34
2.9
2.3
133.90
124.21
g/l
1.96
29
369
70
634
1.11
0.34
4.3
3.2
1.76
1.40
mmol/l
0.72
70
624
12
155
0.77
0.33
1.3
1.6
—
—
—
0
0
22
182
1.21
0.33
1.0
1.1
—
—
—
0
0
68
748
0.91
0.32
1.5
1.9
0.96
1.51
g/l
2.84
61
657
7
96
0.73
0.31
1.7
1.1
—
—
—
0
0
10
129
0.77
0.28
1.4
1.9
10.34
7.55
mmol/l
—
10
129
8
63
1.27
0.27
1.3
1.2
—
—
—
0
0
20
168
1.19
0.27
1.1
1.1
—
—
—
0
0
8
67
1.19
0.26
1.1
1.0
—
—
—
0
0
8
67
1.19
0.26
1.1
1.0
—
—
—
0
0
6
82
0.73
0.24
1.0
1.3
0.93
0.90
g/l
—
6
82
95
891
1.07
0.24
5.4
3.9
36.88
36.92
°c
0.57
95
877
14
169
0.83
0.24
1.3
1.2
—
—
—
0
0
20
233
0.86
0.24
1.8
1.6
5.05
4.12
mmol/24h
0.47
14
198
21
181
1.16
0.22
1.3
1.2
—
—
—
0
0
7
94
0.74
0.22
1.1
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.02
—
0
10
0
14
0.00
0.20
0.0
1.1
—
123.43
—
0
14
30
332
0.90
0.18
1.2
1.2
—
—
—
0
0
51
473
1.08
0.18
1.5
1.5
—
—
—
0
0
518
5268
0.98
0.17
3.1
3.4
74.29
45.95
mg/l
1.23
363
3392
5
69
0.72
0.17
4.2
4.4
—
—
—
0
0
5
70
0.71
0.16
1.0
1.4
1.59
1.55
g/l
—
5
70
16
183
0.87
0.16
2.1
1.7
—
—
—
0
0
10
119
0.84
0.15
1.4
1.3
12.43
10.53
u/l
—
5
91
61
576
1.06
0.15
1.1
1.3
213.98
235.96
u/ml
0.09
56
530
15
133
1.13
0.12
1.0
1.2
7.48
7.42
ph
—
5
93
11
95
1.16
0.11
1.5
2.3
—
37.36
—
0
7
65
621
1.05
0.11
1.4
1.3
—
—
—
0
0
28
300
0.93
0.10
1.0
1.2
—
—
—
0
0
6
55
1.09
0.09
1.2
1.3
138.50
137.09
mmol/l
—
6
43
5
64
0.78
0.08
4.2
4.6
—
—
—
0
0
14
127
1.10
0.08
2.1
1.6
—
—
—
0
0
14
153
0.91
0.07
2.6
1.2
—
—
nmol/l
—
0
0
9
88
1.02
0.07
2.0
3.8
85.11
150.31
nmol/l
—
9
88
14
129
1.09
0.05
1.1
1.2
101.86
113.79
pmol/l
0.27
14
129
130
1321
0.98
0.05
1.3
1.4
—
—
—
0
0
17
179
0.95
0.03
1.1
1.3
—
—
—
0
0
17
179
0.95
0.03
1.1
1.3
—
—
—
0
0
17
179
0.95
0.03
1.1
1.3
—
—
—
0
0
17
179
0.95
0.03
1.1
1.3
—
—
—
0
0
11
102
1.08
0.03
1.0
1.0
—
—
—
0
0
73
742
0.98
0.03
2.2
2.4
13.54
11.58
nmol/l
0.78
59
619
14
133
1.05
0.01
1.3
1.7
3.54
5.00
mg/l
1.98
14
127
12
118
1.02
0.00
2.8
2.1
16.52
16.11
%
0.18
12
118
12
115
1.04
0.00
2.1
2.1
2.29
2.99
ug/l
0.51
12
107
9
99
0.91
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
4.28
—
0
5
0
9
0.00
-0.00
0.0
14.0
—
0.20
—
0
9
6
62
0.97
-0.00
1.2
1.2
0.46
1.01
promille
—
6
45
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
18
180
1.00
-0.00
1.1
1.3
11.44
15.61
u/l
0.55
18
165
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.05
—
0
5
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
7
69
1.01
-0.00
2.4
1.6
65.86
51.50
ug/l
—
7
64
0
5
0.00
-0.00
0.0
1.0
—
34.40
—
0
5

Mortality – FinRegistry

Association

Association between endpoint I9_PROGVASC and mortality.

Females

Parameter HR [95% CI] p-value
I9_PROGVASC 1.801 [1.51, 2.14] < 0.001
Birth year 0.998 [0.99, 1.01] 0.614

During the follow-up period (1.1.1998 — 31.12.2019), 1426 out of 3641 females with I9_PROGVASC died.

Males

Parameter HR [95% CI] p-value
I9_PROGVASC 2.237 [1.78, 2.82] < 0.001
Birth year 0.984 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1110 out of 2445 males with I9_PROGVASC died.

Mortality risk

Mortality risk for people of age

years, who have I9_PROGVASC.

N-year risk Females Males
1 0.181% 0.372%
5 1.113% 2.372%
10 2.898% 6.012%
15 5.374% 11.12%
20 9.441% 18.33%

Relationships between endpoints

Index endpoint: I9_PROGVASC – Progressive vascular leukoencephalopathy

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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