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Follicular adenocarcinoma of thyroid gland, including Hilmo

Endpoint Browser PheWeb

C3_THYROID_FOLLICULAR_WIDE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C73.92&
  • Hospital discharge: ICD-9 — 193B
  • Cause of death: ICD-10 — C73.92&
  • Cause of death: ICD-9 — 193B
  • Cancer registry: Topography ICD-O-3 — C73
  • Cancer registry: Morphology ICD-O-3 — 833[0-2]|8335
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

418

4. Check minimum number of events

None

418

5. Include endpoints

None

418

6. Filter based on genotype QC (FinnGen only)

387

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 387 256 131
Unadjusted period prevalence (%) 0.08 0.09 0.06
Median age at first event (years) 54.36 51.20 60.54

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
400
Matched controls
4000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
104
Kela drug reimbursment
Thyroid insufficiency
65.4
307.7
290
155
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
126.8
307.7
199
31
EP1AE
NOMESCO Finland
Neck ultrasound examination
57.7
307.7
207
73
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
+∞
307.7
367
*
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
+∞
279.0
234
*
H03AA01
ATC
levothyroxine sodium; systemic
129.9
278.0
385
660
BAA60
NOMESCO Finland
Total thyroidectomy
64.6
238.9
137
32
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
67.7
223.2
126
27
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
490.1
183.6
170
6
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
175.3
155
*
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
331.5
168.6
160
8
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
137.7
124
*
ZX114
NOMESCO Finland
Intramuscular
62.5
127.9
72
14
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
46.5
105.1
63
16
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
25.9
80.7
58
26
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
14.0
80.0
80
70
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
+∞
67.7
63
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.8
66.9
252
908
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
65.4
61
*
130
Kela drug reimbursment
Malignant tumour
+∞
64.3
60
*
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
+∞
63.2
59
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
25.3
57.0
41
18
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
56.6
53
*
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
16.4
54.5
48
33
H02AB02
ATC
dexamethasone; systemic
24.6
52.4
38
17
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
+∞
51.2
48
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.4
47.9
203
756
4CJ01, ,
NOMESCO Finland
+∞
46.8
44
*
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
42.5
40
*
XX3DW
NOMESCO Finland
Time consuming IT work
7.9
37.4
55
79
WX402
NOMESCO Finland
General anaesthesia
4.0
35.1
131
430
8290/3-C73.9
ICD-O-3
Oxyphilic adenocarcinoma of thyroid gland
+∞
34.9
33
*
Z51.88
ICD-10 Finland
Other specified medical care
10.9
32.3
36
36
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
31.7
30
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
173.4
31.2
32
*
JN4AD
NOMESCO Finland
Body CT examination
6.3
29.7
54
97
115
Kela drug reimbursment
Breast cancer
+∞
29.5
28
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
29.5
28
*
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
69.3
28.4
32
5
WW200
NOMESCO Finland
Immunization
10.4
27.1
31
32
19399
ICD-8 Finland
Malignant neoplasm of thyroid gland
+∞
26.3
25
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
25.3
24
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
25.3
24
*
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
92.5
24.0
26
*
Z51.5
ICD-10 Finland
Palliative care
6.8
23.6
39
63
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
23.1
22
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
48.0
22.7
27
6
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
22.1
21
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
22.1
21
*
WB223
NOMESCO Finland
Demanding adjuvant hormone therapy of malignancy
+∞
22.1
21
*
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
232.2
21.8
22
*
A04AA02
ATC
granisetron; systemic, transdermal
232.2
21.8
22
*
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
18.8
21.7
33
19
ZXE10
NOMESCO Finland
More than one and less than three hours
2.7
21.0
177
901
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
116.1
20.8
22
*
WF002
NOMESCO Finland
Radical radiotherapy
60.8
20.1
23
*
JN4BD
NOMESCO Finland
Extensive body CT
5.8
19.9
38
71
WZC30
NOMESCO Finland
Teaching
3.5
19.5
78
260
T71
ICPC
Malignant neoplasm thyroid
+∞
18.9
18
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
18.9
18
*
JN6AD
NOMESCO Finland
CT of torso and neck
31.8
18.5
24
8
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
18.0
101
411
106
Kela drug reimbursment
Hypoparathyroidism
99.5
17.7
19
*
HA1AA
NOMESCO Finland
X-ray mammography
5.8
16.9
32
59
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
66.3
16.9
19
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.8
16.9
27
42
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
16.8
119
545
GD1AD
NOMESCO Finland
Thorax CT examination
5.0
16.7
38
83
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
177.1
16.6
17
*
A11CC03
ATC
alfacalcidol; systemic
12.4
16.3
29
25
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
14.7
14
*
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
+∞
14.7
14
*
116
Kela drug reimbursment
Prostate cancer
+∞
14.7
14
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.2
14.5
31
64
A03FA01
ATC
metoclopramide; systemic, rectal
2.9
14.4
81
327
N02AA05
ATC
oxycodone; systemic
2.8
14.2
82
335
GD6AD
NOMESCO Finland
CT of chest and neck
44.2
14.2
17
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
55.4
13.9
16
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
13.6
13
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
13.6
13
*
8335/3-C73.9
ICD-O-3
Follicular carcinoma, minimally invasive of thyroid gland
+∞
13.6
13
*
1930B
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA FOLLICULARE THYREOIDEAE]
+∞
13.6
13
*
JN5SN, ,
NOMESCO Finland
+∞
13.6
13
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
26.8
13.5
18
7
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
23.5
13.0
18
8
NK6AN
NOMESCO Finland
Total body bone isotope imaging
51.8
12.9
15
*
L02BG04
ATC
letrozole; oral
9.8
12.7
25
27
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
12.6
12
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
12.6
12
*
323
Kela drug reimbursment
Sorafenib
+∞
12.6
12
*
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
+∞
12.6
12
*
198
Kela drug reimbursment
Sorafenib
+∞
12.6
12
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
134.0
12.5
13
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
134.0
12.5
13
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
38.9
12.3
15
*
WX704
NOMESCO Finland
Intubation
3.6
11.7
40
119
L03AA13
ATC
pegfilgrastim; parenteral
67.0
11.7
13
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
11.5
11
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
11.5
11
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
11.5
11
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.5
11
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
4.7
11.1
26
58
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
10.8
199
1314
L02BA01
ATC
tamoxifen; oral
61.7
10.7
12
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
4.7
10.6
25
56
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
10.6
94
468
Z31.5
ICD-10 Finland
Genetic counselling
4.4
10.5
27
65
HAC20
NOMESCO Finland
Total mastectomy
112.9
10.5
11
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
112.9
10.5
11
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
10.5
10
*
1508
Kela drug reimbursment
Lenvatinib
+∞
10.5
10
*
2506
FHL
Thyroidectomy
+∞
10.5
10
*
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
+∞
10.5
10
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
10.5
10
*
3019
Kela drug reimbursment
Lenvatinib
+∞
10.5
10
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
41.2
10.0
12
*
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
12.6
9.9
17
14
E04.8
ICD-10 Finland
Other specified nontoxic goitre
56.4
9.7
11
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
9.4
9
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
9.4
9
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
9.4
9
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.2
9.4
38
126
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
37.6
9.1
11
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.3
8.8
23
56
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
51.1
8.7
10
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.8
8.6
26
71
A11CC02
ATC
dihydrotachysterol; oral
28.2
8.5
11
*
BAA99
NOMESCO Finland
Other operation on thyroid gland
91.9
8.4
9
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
91.9
8.4
9
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
91.9
8.4
9
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
8.4
8
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
8.4
8
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
8.4
8
*
JN5AN
NOMESCO Finland
Total body isotope imaging
+∞
8.4
8
*
XX1MN
NOMESCO Finland
Isotope examination with measurement
+∞
8.4
8
*
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
+∞
8.4
8
*
L02BG03
ATC
anastrozole; oral
+∞
8.4
8
*
8339/3-C73.9
ICD-O-3
Follicular carcinoma, encapsulated, angioinvasive of thyroid gland
+∞
8.4
8
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
7.9
48
199
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.2
7.9
73
366
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
13.4
7.9
13
10
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
7.7
54
241
JN4CD
NOMESCO Finland
Very extensive body CT
9.1
7.6
15
17
T86
ICPC
Hypothyroidism/myxoedema
3.1
7.4
31
105
A04AA01
ATC
ondansetron; systemic, rectal
4.3
7.4
19
46
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
7.3
7
*
L01BC06
ATC
capecitabine; oral
+∞
7.3
7
*
L01EX08
ATC
lenvatinib; oral
+∞
7.3
7
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
7.3
7
*
BA1AQ
NOMESCO Finland
Thyroid SPECT with low dose CT
+∞
7.3
7
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
7.3
7
*
C739, ,
ICD-10 Finland
+∞
7.3
7
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
7.3
7
*
C73.93
ICD-10 Finland
Anaplastic thyroid carcinoma (thyroid)
+∞
7.3
7
*
X76
ICPC
Malignant neoplasm breast female
+∞
7.3
7
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
7.3
7
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
7.3
7
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
20.5
7.2
10
5
B01AB05
ATC
enoxaparin; parenteral
1.9
7.1
117
722
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.5
6.9
45
194
E03.89
ICD-10 Finland
Other specified hypothyroidism
3.2
6.6
26
85
A12AA04
ATC
calcium carbonate; oral
10.3
6.6
12
12
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
10.3
6.6
12
12
XKD00
NOMESCO Finland
Uroflowmetry
2.4
6.5
47
212
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
70.9
6.4
7
*
ZSB00
NOMESCO Finland
Procedure related to previous procedure classified in chapter B
70.9
6.4
7
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
70.9
6.4
7
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
70.9
6.4
7
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
70.9
6.4
7
*
WX725
NOMESCO Finland
Noninvasive ventilation
3.0
6.3
28
98
ZXA00
NOMESCO Finland
Right side
1.8
6.3
107
664
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
6.3
6
*
1930A
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA PAPILLARE THYREOIDEAE]
+∞
6.3
6
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
6.3
6
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
L01EX02
ATC
sorafenib; oral
+∞
6.3
6
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
6.3
6
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
6.3
6
*
Y77
ICPC
Malignant neoplasm prostate
+∞
6.3
6
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.9
6.2
16
28
ZXE00
NOMESCO Finland
One hour or less
1.7
6.0
151
1047

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
268
205
37.59
315.37
9.6
3.6
4.60
4.56
pmol/l
0.14
263
181
109
38
39.05
168.91
1.5
1.2
—
—
—
0
0
110
82
18.12
122.71
1.4
1.3
—
—
—
0
0
249
964
5.19
58.45
8.9
3.2
7.40
7.40
ph
0.26
210
689
325
1632
6.29
53.25
13.3
6.0
1.20
1.22
mmol/l
2.57
276
1422
300
1452
5.26
50.28
10.5
5.5
1.21
1.22
mmol/l
1.53
288
1323
113
269
5.46
46.82
2.1
3.8
45.49
81.67
ng/l
12.60
99
237
102
266
4.80
37.29
1.6
1.1
—
—
—
0
0
236
1115
3.72
36.84
5.2
2.0
2.31
2.36
mmol/l
6.77
229
971
90
230
4.76
33.50
6.9
2.7
1.20
1.23
mmol/l
2.99
85
198
45
60
8.32
32.50
2.6
2.6
4.67
9.88
pmol/l
2.21
45
60
65
159
4.69
25.20
3.4
1.6
4.30
2.57
ug/l
0.54
51
121
373
2755
6.24
23.68
14.2
4.4
17.85
14.79
pmol/l
55.24
360
2536
207
1113
2.78
22.37
2.7
1.7
—
—
—
0
0
244
1447
2.76
21.43
2.8
2.4
—
—
estimate
—
0
0
231
1425
2.47
17.31
5.4
3.7
36.44
36.22
g/l
0.29
220
1336
249
1613
2.44
16.38
3.0
2.6
80.83
77.96
nmol/l
1.01
235
1447
173
976
2.36
15.34
2.5
2.0
—
—
—
0
0
247
1660
2.28
14.00
7.9
3.7
11.06
11.23
umol/l
0.11
237
1576
329
2522
2.72
13.57
11.6
5.6
76.88
74.98
u/l
0.49
316
2353
36
95
4.07
12.47
2.3
2.4
3.65
5.44
iu/l
0.50
17
44
258
1815
2.19
12.39
9.3
6.3
3.98
4.23
e9/l
1.07
223
1573
270
1988
2.10
10.80
4.9
4.3
6.51
6.66
mmol/l
0.44
257
1873
376
3227
3.75
10.18
19.3
5.5
2.76
1.89
mu/l
0.50
363
2996
42
143
3.16
9.95
1.6
1.4
38.20
28.18
u/ml
0.33
42
138
212
1499
1.88
8.76
14.1
14.2
1.24
1.25
inr
0.16
178
1255
58
263
2.41
7.95
4.3
3.2
—
—
—
0
0
11
6
18.80
7.64
2.9
1.0
18.27
14.83
u/ml
—
11
6
77
415
2.06
6.91
4.1
4.8
1.07
1.03
mmol/l
0.63
68
369
51
235
2.34
6.73
4.5
4.1
0.58
0.23
%
0.48
12
47
132
861
1.80
6.63
1.5
1.4
—
—
—
0
0
150
1019
1.76
6.54
4.7
3.7
0.00
0.00
estimate
-0.00
62
345
139
939
1.74
6.10
3.0
2.9
0.39
0.41
e6/l
0.06
107
690
50
243
2.21
5.82
4.7
4.3
0.09
0.05
%
0.18
11
42
51
252
2.17
5.70
4.8
4.2
0.50
0.68
%
0.33
12
51
156
1105
1.68
5.67
3.1
3.1
65.41
98.21
e6/l
0.21
124
842
26
94
2.89
5.58
2.5
2.0
—
—
—
0
0
104
664
1.77
5.49
3.1
2.7
525.54
521.89
mosm/kgh2o
0.06
86
581
51
256
2.14
5.48
4.8
4.5
0.18
0.00
%
0.78
11
41
122
816
1.71
5.46
4.1
3.7
—
—
—
0
0
8
5
16.27
5.43
5.4
1.6
86.25
59.60
nmol/l
—
8
5
117
776
1.72
5.38
2.9
2.3
4.40
6.28
e6/l
1.42
104
705
10
12
8.51
5.09
1.9
1.6
12.34
14.99
ug/l
—
10
12
196
1503
1.60
5.01
15.8
9.6
0.00
0.00
e9/l
0.49
169
1238
171
1277
1.59
4.84
3.6
3.7
52.83
124.52
e6/l
1.53
130
884
370
3375
2.28
4.73
22.0
13.1
22.38
22.09
mg/l
0.05
314
2695
143
1036
1.59
4.54
4.5
3.1
0.00
0.00
estimate
-0.00
61
295
15
39
3.95
4.24
1.3
1.2
—
—
—
0
0
183
1431
1.51
4.00
5.0
3.5
0.05
0.03
estimate
0.18
59
290
27
119
2.36
3.97
1.8
2.2
9027.20
9686.60
u/l
—
6
50
373
3451
2.20
3.96
22.5
16.1
139.94
139.76
mmol/l
0.76
367
3377
373
3455
2.18
3.88
23.0
16.1
3.93
3.97
mmol/l
2.50
366
3376
177
1382
1.50
3.86
3.9
3.7
24.98
105.60
ng/l
1.02
127
973
230
1902
1.49
3.74
4.9
3.7
0.00
0.02
estimate
0.93
69
351
226
1863
1.49
3.73
4.8
3.6
0.00
0.00
estimate
-0.00
68
360
228
1884
1.49
3.71
4.9
3.7
0.00
0.00
estimate
-0.00
70
367
15
51
3.02
3.61
1.9
3.3
4.10
4.11
e9/l
0.00
15
51
10
22
4.63
3.45
1.3
1.2
—
—
—
0
0
18
70
2.65
3.43
1.7
1.3
74.61
109.54
pmol/l
0.28
18
70
106
758
1.54
3.43
5.3
4.2
—
—
—
0
0
23
101
2.36
3.43
4.0
2.8
25.87
24.77
mmol/l
0.48
23
101
140
1074
1.47
3.20
6.0
5.4
—
—
—
0
0
6
8
7.59
3.06
1.2
1.0
—
—
—
0
0
6
8
7.59
3.06
1.0
1.0
—
—
—
0
0
44
258
1.79
3.06
1.3
1.3
73.80
116.86
u/ml
0.75
18
117
19
81
2.41
3.03
4.7
1.3
20.93
1.50
ratio
0.46
12
51
15
57
2.70
3.00
4.8
2.8
—
—
—
0
0
37
210
1.84
2.86
6.0
4.0
5.35
5.16
kpa
0.63
37
203
19
84
2.32
2.82
1.3
1.2
15.97
11.70
u/l
0.25
13
70
373
3511
1.92
2.81
21.6
12.0
—
—
—
0
0
8
18
4.51
2.81
1.1
1.1
162.38
182.26
mmol/24h
—
8
18
209
1759
1.39
2.74
6.1
5.7
0.17
0.20
e9/l
1.77
180
1544
16
68
2.41
2.59
1.8
3.0
62.83
58.74
%
0.67
16
68
201
1692
1.38
2.58
6.1
5.6
0.56
0.56
e9/l
0.06
173
1457
138
1093
1.40
2.55
2.4
2.2
108.13
58.18
u/l
1.11
121
1012
54
353
1.61
2.55
5.3
7.1
0.74
1.22
mmol/l
0.52
45
293
67
461
1.54
2.55
2.7
2.3
22.38
22.63
%
0.04
61
432
55
362
1.60
2.53
5.3
7.0
7.41
7.42
ph
0.35
32
211
29
161
1.86
2.42
1.1
1.3
31.77
24.12
iu/l
0.49
24
142
13
52
2.55
2.38
1.1
1.2
—
—
—
0
0
12
46
2.66
2.38
1.3
1.4
—
—
—
0
0
5
8
6.31
2.38
1.4
1.3
102.60
241.63
e6/l
—
5
8
200
1705
1.35
2.27
6.1
5.6
0.04
0.04
e9/l
0.42
172
1471
19
93
2.10
2.25
4.8
1.4
32.16
30.13
mg/l
0.09
14
82
19
93
2.10
2.25
4.8
1.4
37.49
43.75
mg/l
0.32
14
84
55
373
1.55
2.24
1.9
2.3
6.89
6.46
umol/l
0.08
47
332
202
1728
1.34
2.23
6.3
5.6
1.70
1.87
e9/l
2.63
179
1536
45
293
1.60
2.17
9.6
4.1
7.38
7.36
ph
0.62
37
197
51
345
1.55
2.10
2.2
2.0
405.13
378.86
nmol/l
0.19
46
318
5
10
5.05
2.07
1.4
1.4
—
—
—
0
0
6
15
4.04
2.04
1.3
1.3
70.17
71.27
%
—
6
15
181
1545
1.31
1.95
6.5
5.6
0.67
0.68
%
0.14
167
1441
8
27
3.00
1.94
3.1
2.7
—
—
—
0
0
6
16
3.79
1.94
2.5
1.3
0.62
0.93
e9/l
—
6
16
180
1539
1.31
1.90
6.5
5.6
8.87
8.64
%
0.62
166
1443
25
144
1.79
1.90
4.2
3.6
1.00
0.90
%
0.86
25
138
57
409
1.46
1.80
1.5
1.7
—
—
—
0
0
12
54
2.26
1.75
1.2
1.2
9.58
17.71
u/l
1.11
12
47
183
1581
1.29
1.75
6.2
5.5
26.67
28.01
%
0.97
171
1501
32
203
1.63
1.74
3.3
1.4
—
—
—
0
0
117
955
1.32
1.70
6.9
4.4
—
—
—
0
0
6
19
3.19
1.66
1.0
1.2
—
—
—
0
0
6
19
3.19
1.66
1.0
1.4
—
—
—
0
0
178
1543
1.28
1.62
6.4
5.5
2.65
3.01
%
1.61
164
1442
8
32
2.53
1.60
1.1
1.7
20.30
22.20
ng/l
—
8
32
6
20
3.03
1.58
1.0
1.3
—
—
—
0
0
22
130
1.73
1.56
1.2
1.3
—
—
—
0
0
130
1089
1.29
1.54
3.1
3.3
1132.87
1345.95
ng/l
0.40
112
916
49
353
1.44
1.53
1.4
1.4
—
—
—
0
0
5
15
3.36
1.53
1.2
1.3
15.00
12.87
%
—
5
15
7
27
2.62
1.52
1.1
1.1
114.29
103.74
pmol/l
—
7
27
109
896
1.30
1.49
2.6
2.3
3.59
2.83
mg/l
2.09
96
769
25
156
1.64
1.47
4.6
3.5
1.66
1.59
%
0.27
25
151
130
1095
1.28
1.47
3.2
3.0
—
—
—
0
0
19
111
1.75
1.41
1.1
1.3
—
—
—
0
0
6
23
2.63
1.37
1.0
1.3
—
—
—
0
0
0
37
0.00
1.35
0.0
2.3
—
—
—
0
0
174
1532
1.24
1.32
4.1
3.3
6.32
6.23
ph
0.46
107
880
371
3581
1.50
1.29
15.2
9.8
23.88
25.16
u/l
1.12
364
3468
188
1674
1.23
1.28
3.6
3.0
96.47
102.22
ug/l
0.21
177
1563
176
1569
1.22
1.15
6.4
5.5
59.20
57.56
%
1.07
167
1495
66
527
1.30
1.12
2.2
2.9
8.63
2.85
e6/l
0.68
34
242
27
185
1.49
1.11
3.7
4.2
—
—
—
0
0
50
384
1.35
1.11
1.7
1.6
—
—
—
0
0
16
98
1.66
1.05
1.6
1.3
297.77
338.61
ug/g
—
9
58
101
861
1.23
1.01
3.4
2.3
354.59
343.86
umol/l
0.46
87
753
58
463
1.30
1.00
1.5
1.8
—
—
—
0
0
28
199
1.44
0.98
4.8
6.0
24.63
24.77
mmol/l
0.11
28
193
15
92
1.65
0.98
1.2
1.1
—
—
—
0
0
14
85
1.67
0.95
5.9
3.9
1.83
1.58
mg/l
0.50
14
74
0
32
0.00
0.95
0.0
1.1
—
3.28
—
0
6
27
192
1.44
0.95
2.1
1.8
—
—
—
0
0
20
289
0.68
0.92
1.4
1.9
3.10
3.42
mmol/l
—
10
224
35
263
1.36
0.91
1.3
1.3
—
—
—
0
0
6
30
2.01
0.87
1.2
1.1
—
—
—
0
0
26
188
1.41
0.85
2.8
2.4
—
—
—
0
0
6
31
1.95
0.84
1.0
1.2
—
—
—
0
0
18
121
1.51
0.84
15.9
7.8
—
—
—
0
0
6
114
0.52
0.84
1.3
1.8
25.50
20.08
s
—
6
105
94
812
1.21
0.83
5.7
4.1
2.30
1.87
ug/l
0.66
84
737
6
32
1.89
0.82
2.5
1.2
33.17
33.41
pg
—
6
32
10
58
1.74
0.80
1.0
1.1
—
—
—
0
0
99
864
1.19
0.78
5.5
3.6
1.02
1.02
kg/l
0.24
66
571
72
612
1.22
0.75
1.9
1.9
—
—
—
0
0
378
3702
1.38
0.74
34.5
20.1
252.58
250.75
e9/l
0.23
373
3639
7
40
1.76
0.71
1.4
2.0
17.19
97.57
u/ml
—
7
40
378
3704
1.37
0.71
34.5
20.1
6.45
6.66
e9/l
1.52
373
3629
378
3704
1.37
0.71
34.4
20.1
4.52
4.50
e12/l
0.42
372
3632
10
61
1.66
0.69
1.2
1.3
277.20
202.77
u/ml
—
5
31
7
43
1.64
0.67
6.0
3.5
—
—
—
0
0
7
44
1.60
0.65
1.4
1.4
—
—
—
0
0
58
491
1.21
0.64
1.2
1.2
—
—
—
0
0
5
29
1.73
0.64
1.0
1.2
24.16
25.56
g/l
—
5
24
5
30
1.67
0.61
3.8
1.6
623.20
788.97
mg
—
5
30
58
494
1.20
0.61
1.5
1.6
—
—
—
0
0
43
355
1.24
0.61
2.5
3.3
7.39
7.39
ph
0.16
28
220
35
282
1.26
0.60
3.5
2.5
6.00
6.09
ph
0.24
25
192
56
476
1.21
0.60
2.7
1.8
29.46
29.31
s
0.05
56
463
8
52
1.55
0.60
1.0
1.0
—
—
—
0
0
33
265
1.27
0.59
6.0
8.1
—
—
—
0
0
0
23
0.00
0.58
0.0
15.3
—
847.13
—
0
23
244
2319
1.13
0.58
3.9
3.1
43.67
41.19
u/l
0.23
223
2183
40
330
1.24
0.57
1.9
2.0
0.00
0.07
estimate
—
8
71
44
367
1.22
0.57
2.0
1.5
—
—
—
0
0
41
341
1.23
0.55
2.5
3.2
2.20
1.79
mmol/l
0.39
33
293
20
151
1.34
0.55
6.0
4.1
—
—
—
0
0
59
513
1.18
0.51
1.4
1.4
240.00
507.79
titre
2.85
11
131
16
118
1.37
0.51
6.6
4.7
26.17
25.05
mmol/l
0.53
16
110
22
171
1.30
0.51
1.1
1.1
—
14.20
—
0
5
42
354
1.21
0.50
1.5
1.5
—
—
—
0
0
10
67
1.51
0.50
1.4
1.5
—
—
—
0
0
17
128
1.34
0.48
1.1
1.2
0.89
0.87
g/l
0.20
17
128
25
307
0.80
0.45
1.0
1.2
—
—
—
0
0
53
464
1.16
0.43
4.1
2.8
0.71
0.75
ug/l
0.15
35
289
82
742
1.13
0.43
1.8
1.7
504.34
6472932.15
pmol/l
0.50
70
618
114
1055
1.11
0.41
1.8
1.6
20.09
20.47
nmol/l
0.10
106
899
7
104
0.67
0.40
1.1
1.2
594.00
435.65
mg/l
—
7
96
8
61
1.32
0.39
1.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
18
143
1.27
0.37
1.2
1.6
—
17.88
—
0
5
5
76
0.65
0.36
1.8
1.3
—
—
—
0
0
17
135
1.27
0.36
1.2
1.5
—
—
—
0
0
16
126
1.28
0.35
1.0
1.1
1.37
1.58
g/l
3.58
16
126
35
302
1.17
0.35
2.1
2.5
4.91
6.38
ug/l
0.36
28
262
112
1195
0.91
0.33
3.9
3.4
87.82
43.16
mg/l
0.63
67
746
17
137
1.25
0.32
1.3
1.5
—
—
—
0
0
17
137
1.25
0.32
1.3
1.5
—
—
—
0
0
62
681
0.89
0.32
4.2
4.0
257.56
392.35
ng/l
0.22
52
527
12
153
0.78
0.31
1.0
1.1
—
—
—
0
0
17
138
1.24
0.31
1.3
1.5
—
—
—
0
0
15
121
1.25
0.29
1.4
1.3
1.58
14.10
u/ml
—
6
25
11
86
1.29
0.26
1.5
1.5
19793.67
18005.69
e6/l
—
6
55
116
1218
0.93
0.23
4.8
4.0
14.96
7.17
mg/mmol
0.69
67
738
5
38
1.32
0.23
2.0
1.2
—
—
—
0
0
5
38
1.32
0.23
2.0
1.2
—
—
—
0
0
5
38
1.32
0.23
2.0
1.2
—
—
—
0
0
5
38
1.32
0.23
2.0
1.2
—
—
—
0
0
16
134
1.20
0.23
1.2
1.5
—
—
—
0
0
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
7
92
0.76
0.22
1.1
1.2
3.99
3.82
mmol/l
—
7
85
30
336
0.88
0.22
1.6
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
27.70
—
0
10
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
20
173
1.16
0.21
1.3
1.2
—
—
—
0
0
19
164
1.17
0.20
2.1
2.0
0.00
0.02
estimate
—
8
54
25
221
1.14
0.20
1.6
1.4
—
—
—
0
0
122
1273
0.94
0.20
3.7
3.2
7.43
7.53
mmol/l
0.10
109
1077
39
426
0.91
0.20
1.4
1.4
—
—
—
0
0
6
50
1.20
0.20
1.8
1.2
—
—
—
0
0
338
3338
1.08
0.19
5.1
5.1
5.85
5.93
mmol/l
0.62
315
3073
84
886
0.93
0.19
1.4
1.3
1.84
1.35
u/ml
0.27
29
255
6
52
1.16
0.19
2.5
1.3
0.48
0.59
nmol/l
—
6
46
35
320
1.10
0.18
2.5
2.1
34.33
35.90
u/l
0.10
30
262
156
1608
0.95
0.17
2.1
2.1
96.39
98.38
pmol/l
0.23
86
811
5
67
0.74
0.17
1.0
2.0
26.60
34.45
umol/l
—
5
62
5
67
0.74
0.17
1.8
1.7
—
—
—
0
0
5
67
0.74
0.17
1.0
1.2
—
—
—
0
0
18
158
1.15
0.16
1.7
2.1
5.17
6.27
iu/ml
—
7
41
142
1376
1.05
0.16
3.3
3.2
—
—
—
0
0
6
77
0.78
0.15
1.0
1.1
—
—
—
0
0
336
3393
0.94
0.15
5.0
5.1
1.45
1.50
mmol/l
1.53
316
3161
7
86
0.81
0.14
1.3
1.5
—
—
—
0
0
7
89
0.78
0.14
1.3
1.6
—
—
—
0
0
149
1532
0.96
0.14
2.2
1.9
1.41
1.33
mmol/l
0.67
124
1315
10
84
1.20
0.14
1.6
1.7
—
—
—
0
0
11
94
1.18
0.13
2.6
2.4
38.33
92.91
ug/min
—
6
57
320
3231
0.95
0.12
4.2
4.3
1.33
1.27
mmol/l
1.02
298
2980
51
485
1.06
0.11
2.1
2.6
113.71
109.20
ug/g
0.05
39
367
323
3256
0.96
0.10
6.6
6.5
38.98
39.21
mmol/mol
0.20
301
3058
5
45
1.11
0.10
2.8
1.3
—
—
nmol/l
—
0
0
5
47
1.06
0.09
1.0
1.1
—
5.75
—
0
20
58
603
0.96
0.09
2.3
1.7
1412.09
1220.76
nmol/l
0.62
47
459
32
339
0.94
0.09
1.7
1.4
—
—
—
0
0
12
134
0.89
0.09
1.2
1.3
—
—
—
0
0
339
3411
0.96
0.08
5.2
5.2
4.62
4.64
mmol/l
0.14
320
3194
6
73
0.82
0.07
1.0
1.6
1.34
0.88
nmol/l
—
6
57
10
112
0.89
0.07
1.5
1.2
—
—
—
0
0
10
89
1.13
0.07
5.1
4.4
—
—
—
0
0
8
91
0.88
0.07
1.0
1.1
—
—
—
0
0
10
111
0.90
0.06
2.8
3.8
1.35
1.32
mmol/l
—
10
106
77
752
1.03
0.06
1.6
1.3
2.06
2.48
g/l
1.84
58
443
347
3455
1.03
0.05
5.8
5.9
2.74
2.70
mmol/l
0.39
326
3231
77
786
0.97
0.05
1.5
1.6
0.74
1.10
mg/l
1.72
62
603
35
362
0.96
0.04
1.7
1.7
—
—
—
0
0
19
180
1.06
0.04
1.8
1.8
—
—
—
0
0
19
200
0.95
0.04
1.1
1.1
—
—
—
0
0
66
673
0.98
0.03
1.5
1.3
16.90
11.50
u/ml
0.21
30
256
18
189
0.95
0.03
1.9
2.5
1.00
1.17
%
0.80
18
189
72
729
0.98
0.02
1.5
1.4
15.69
35.90
iu/ml
3.90
26
219
13
123
1.06
0.01
4.9
2.8
261.83
260.63
mg/l
—
6
43
28
274
1.02
0.00
5.1
5.6
10.60
9.55
mmol/l
0.26
23
260
12
117
1.03
0.00
1.2
1.5
—
—
—
0
0
18
185
0.97
0.00
1.9
2.4
0.64
0.60
%
0.20
18
185
5
59
0.85
0.00
1.0
1.0
—
1.45
—
0
31
6
63
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.1
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.0
—
4.15
—
0
26
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
24
240
1.00
-0.00
1.3
1.4
—
42.85
—
0
21
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.40
—
0
7
5
58
0.86
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
9.20
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
134.00
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
0.05
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
74.67
—
0
6
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
69.43
—
0
7
0
9
0.00
-0.00
0.0
5.4
—
7.94
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_THYROID_FOLLICULAR_WIDE – Follicular adenocarcinoma of thyroid gland, including Hilmo

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).