Disorders of orbit

H7_ORBIT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H05, H06*
  • Cause of death: ICD-10 H05, H06*

2 out of 7 registries used, show all original rules.

1804

4. Check minimum number of events

None

1804

5. Include endpoints

1914

6. Filter based on genotype QC (FinnGen only)

1747

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11521 7147 4305
Only index persons 10492 6687 3805
Unadjusted period prevalence (%)
Whole population 0.17 0.20 0.12
Only index persons 0.21 0.25 0.15
Median age at first event (years)
Whole population 48.52 51.10 44.14
Only index persons 48.17 50.74 43.66

-FinnGen-

Key figures

All Female Male
Number of individuals 1747 1224 523
Unadjusted period prevalence (%) 0.38 0.43 0.24
Median age at first event (years) 52.95 52.40 54.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1812
Matched controls
18120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H03AA01
ATC
levothyroxine sodium; systemic
6.1
307.7
995
3031
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
307.7
387
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
93.8
307.7
193
23
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
20.6
307.7
286
163
H03BB01
ATC
carbimazole; oral
41.7
307.7
817
350
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
307.7
856
*
BAA60
NOMESCO Finland
Total thyroidectomy
21.7
307.7
362
206
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
80.7
307.7
881
210
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
122.5
307.7
187
17
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
38.3
307.7
543
200
104
Kela drug reimbursment
Thyroid insufficiency
7.7
267.5
440
727
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
244.4
229
*
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
25.8
233.4
165
70
H062, E050,
ICD-10 Finland
+∞
231.3
217
*
H05.0
ICD-10 Finland
Acute inflammation of orbit
2199.7
218.1
207
*
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
23.6
216.0
158
73
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.6
215.9
1208
5457
H04.10
ICD-10 Finland
Dry eye syndrome
6.5
190.6
353
648
H53.2
ICD-10 Finland
Diplopia
10.4
187.9
220
237
H50.2
ICD-10 Finland
Vertical strabismus
32.8
171.4
111
36
H02.3
ICD-10 Finland
Blepharochalasis
25.1
169.0
120
51
H02.4
ICD-10 Finland
Ptosis of eyelid
29.2
144.6
97
35
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.8
138.3
554
1871
XCK00
NOMESCO Finland
Perimetry
6.2
132.5
247
450
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.6
126.2
350
900
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
122.7
903
4371
H05.1
ICD-10 Finland
Chronic inflammatory disorders of orbit
+∞
104.2
99
*
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
51.7
104.1
60
12
H05.8
ICD-10 Finland
Other disorders of orbit
+∞
102.0
97
*
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
101.0
96
*
C07AA05
ATC
propranolol; systemic
3.0
98.6
586
2458
H02AB06
ATC
prednisolone; systemic
2.7
90.5
1073
6352
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
34.8
85.1
54
16
CEC00
NOMESCO Finland
Recession of extraocular muscle
38.2
84.1
52
14
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
32.7
83.6
54
17
T85
ICPC
Hyperthyroidism/thyrotoxicosis
13.9
71.0
66
49
CA1AD
NOMESCO Finland
Orbita CT
99.1
69.5
76
8
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.8
61.3
380
1584
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
60.8
58
*
H57.1
ICD-10 Finland
Ocular pain
4.9
59.6
137
297
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.3
58.9
161
401
XCK10
NOMESCO Finland
Photography of fundus of eye
3.2
53.9
231
780
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.7
53.7
184
538
T86
ICPC
Hypothyroidism/myxoedema
3.9
51.8
165
459
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.4
51.4
136
330
CAA30
NOMESCO Finland
Biopsy of orbit
113.4
51.1
55
5
ZXA10
NOMESCO Finland
Bilateral
2.5
51.0
390
1787
ZX120
NOMESCO Finland
Intravenous
3.0
49.7
246
902
H50.6
ICD-10 Finland
Mechanical strabismus
501.2
49.6
49
*
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
8.0
49.5
68
88
WF099
NOMESCO Finland
Other radiotherapy
16.8
48.8
41
25
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.1
48.5
649
3752
H02AB07
ATC
prednisone; oral
2.6
48.5
323
1383
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.1
47.8
103
211
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.9
46.7
85
149
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
6.2
46.0
80
134
A02BC02
ATC
pantoprazole; systemic
2.2
44.3
1336
10253
H01.0
ICD-10 Finland
Blepharitis
3.5
43.2
162
501
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
41.9
526
2940
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
15.1
41.7
37
25
H50.0
ICD-10 Finland
Convergent concomitant strabismus
10.2
41.7
47
47
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
395.8
39.2
39
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.8
38.8
216
839
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
38.5
697
4411
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
13.0
38.4
37
29
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
38.2
459
2509
CAC44
NOMESCO Finland
Combined decompression of orbit
385.3
38.2
38
*
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
73.2
38.1
43
6
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
37.8
726
4679
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
37.0
890
6153
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
9.2
37.0
45
50
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.2
36.6
156
522
L04AX03
ATC
methotrexate; systemic
2.6
36.3
240
1016
Z3231
NOMESCO Finland
Registered nurse
2.0
35.7
531
3127
CAC20
NOMESCO Finland
Lateral decompression of orbit
+∞
35.5
34
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
11.4
35.4
37
33
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
183.5
34.9
36
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
6.5
34.2
56
88
CS494
NOMESCO Finland
Other visual field testing
4.5
34.1
84
192
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
8.5
33.9
44
53
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
178.3
33.8
35
*
E03
ICD-10 Finland
Other hypothyroidism
2.9
33.7
169
620
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
7.4
33.6
49
68
H50.8
ICD-10 Finland
Other specified strabismus
56.9
33.3
39
7
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.6
33.2
204
831
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
118.9
32.8
35
*
3760A
ICD-9 Finland
Disorders of the orbit, Acute inflammation of orbit
+∞
32.4
31
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
86.7
30.8
34
*
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
30.3
29
*
F29
ICPC
Eye symptom/complaint other
2.4
30.1
231
1044
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
84.1
29.8
33
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.8
29.5
93
256
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
+∞
29.2
28
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
40.8
29.0
36
9
C07AB07
ATC
bisoprolol; oral
1.7
29.0
853
6113
L04AA06
ATC
mycophenolic acid; systemic
5.3
28.4
58
113
WX002
NOMESCO Finland
Sedation and analgesia
2.0
28.0
364
2023
CA1BD
NOMESCO Finland
Extensive orbita CT
101.7
27.7
30
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
26.9
399
2316
1XC02, ,
NOMESCO Finland
9.5
26.2
31
33
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
25.8
166
690
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
264.3
25.8
26
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.5
25.2
90
269
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.0
25.2
73
189
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
25.1
24
*
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
253.5
24.7
25
*
WX402
NOMESCO Finland
General anaesthesia
1.8
24.7
451
2789
H05.5
ICD-10 Finland
Retained (old) foreign body following penetrating wound of orbit
+∞
24.0
23
*
WF002
NOMESCO Finland
Radical radiotherapy
3.0
24.0
108
372
H02AB09
ATC
hydrocortisone; systemic
3.9
23.6
69
180
ZXE00
NOMESCO Finland
One hour or less
1.7
23.5
695
4906
UDM02
NOMESCO Finland
Sinoscopy
4.2
23.5
63
154
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.7
23.1
128
493
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
2.6
22.7
135
539
A11CC03
ATC
alfacalcidol; systemic
4.2
22.7
60
145
N05CF01
ATC
zopiclone; oral
1.7
22.6
583
3962
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.5
22.0
152
652
H10.4
ICD-10 Finland
Chronic conjunctivitis
8.2
21.8
29
36
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
21.7
222
1123
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
22.5
21.7
31
14
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
6.6
21.3
34
52
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
50.6
21.1
25
5
H02.8
ICD-10 Finland
Other specified disorders of eyelid
34.2
21.1
27
8
XCH00
NOMESCO Finland
Eye pressure measurement
2.9
20.6
99
354
H50.1
ICD-10 Finland
Divergent concomitant strabismus
8.3
20.5
27
33
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
3.8
20.5
64
175
2AB04, ,
NOMESCO Finland
19.0
20.0
30
16
CEW99
NOMESCO Finland
Other operation on extraocular muscle
58.2
19.9
23
*
E05.5
ICD-10 Finland
Thyroid crisis or storm
74.3
19.7
22
*
S01ED01
ATC
timolol; ophthalmic
3.5
19.7
68
199
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.4
19.7
145
640
H02.1
ICD-10 Finland
Ectropion of eyelid
55.6
18.9
22
*
Z2221
NOMESCO Finland
Medical doctor
1.7
18.8
489
3301
H05.4
ICD-10 Finland
Enophthalmos
+∞
18.8
18
*
F01
ICPC
Eye pain
3.3
18.7
70
216
AA1AD
NOMESCO Finland
CT of head and brain
1.7
18.7
487
3288
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.2
18.7
76
247
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
191.9
18.6
19
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
191.9
18.6
19
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
18.4
142
640
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.9
18.3
28
41
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
6.2
18.1
31
51
ZXA00
NOMESCO Finland
Right side
1.7
18.0
439
2910
R51.80
ICD-10 Finland
Headache
1.8
18.0
305
1827
E05.89
ICD-10 Finland
Other thyrotoxicosis
18.3
17.8
27
15
WX140
NOMESCO Finland
Parabulbar anesthesy
2.8
17.7
93
349
CE2W4
NOMESCO Finland
Eye movement mapping
18.8
17.3
26
14
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
42.4
17.3
21
5
J01DB01
ATC
cefalexin; oral
1.7
17.2
1474
13019
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
31.8
17.0
22
7
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
17.0
476
3260
Z3226
NOMESCO Finland
Physiotherapist
1.8
16.9
320
1977
3763A
ICD-9 Finland
Disorders of the orbit, Other exophthalmic conditions
+∞
16.7
16
*
CBA10
NOMESCO Finland
Biopsy of eyelid
6.5
16.7
27
42
N02AX02
ATC
tramadol; systemic, rectal
1.5
16.6
730
5537
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.2
16.6
141
661
S01KA02
ATC
hypromellose; ophthalmic
4.2
16.6
44
107
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
16.5
16.6
26
16
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
171.5
16.5
17
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
16.4
373
2420
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
6.4
16.3
27
43
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
16.2
223
1249
DPA30
NOMESCO Finland
Sphenotomy
6.8
16.2
25
37
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.4
15.9
58
176
H02.2
ICD-10 Finland
Lagophthalmos
60.6
15.8
18
*
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.2
15.7
61
193
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
15.7
1275
10959
CCA10
NOMESCO Finland
Biopsy of lacrimal gland
+∞
15.6
15
*
CAA00
NOMESCO Finland
Puncture of orbital abscess
+∞
15.6
15
*
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
85.8
15.6
17
*
ZXA05
NOMESCO Finland
Left side
1.6
15.3
393
2628
R4110
NOMESCO Finland
Physiotherapy
1.6
15.2
482
3386
S01XA18
ATC
ciclosporin; ophthalmic
20.2
15.1
22
11
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.8
15.1
264
1590
N02BE01
ATC
paracetamol; systemic, rectal
1.8
15.0
1601
14609
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
5.2
14.9
30
58
ZXD20
NOMESCO Finland
Day surgery
1.8
14.7
228
1325
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
+∞
14.6
14
*
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
+∞
14.6
14
*
3762A
ICD-9 Finland
Disorders of the orbit, Endocrine exophthalmos
+∞
14.6
14
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
14.5
466
3279
CD2S4
NOMESCO Finland
Photography of eye
10.5
14.2
27
26
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
11.0
14.0
26
24
S01ED51
ATC
timolol, combinations; ophthalmic
2.2
14.0
127
612
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
6.1
13.9
24
40
H04.0
ICD-10 Finland
Dacryoadenitis
24.0
13.8
19
8
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
13.7
220
1291
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
13.6
13
*
CAE10
NOMESCO Finland
Revision and secondary implant in orbit
+∞
13.6
13
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
4.6
13.6
32
71
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
13.4
152
795
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.3
13.4
27
52
A02BC01
ATC
omeprazole; systemic
1.5
13.2
450
3198
H02AB04
ATC
methylprednisolone; systemic
1.7
13.2
247
1515
H00.1
ICD-10 Finland
Chalazion
3.1
13.2
55
182
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.0
13.1
139
710
106
Kela drug reimbursment
Hypoparathyroidism
12.2
13.1
23
19
A97
ICPC
No disease
1.6
13.1
349
2346
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.9
13.0
172
948
CBB00
NOMESCO Finland
Excision of chalazion
28.6
13.0
17
6
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
28.6
13.0
17
6
H40.0
ICD-10 Finland
Glaucoma suspect
2.0
12.9
141
728
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
12.9
483
3502
S01EA05
ATC
brimonidine; ophthalmic
3.3
12.6
46
140
N07BA03
ATC
varenicline; oral
2.3
12.6
95
424
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.6
12.6
41
116
CBH30
NOMESCO Finland
Tarsorraphy
+∞
12.5
12
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
12.5
12
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
12.5
12
*
H02.9
ICD-10 Finland
Disorder of eyelid, unspecified
20.2
12.5
18
9
CAW99
NOMESCO Finland
Other operation on orbit
130.9
12.4
13
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
12.4
214
1282
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
12.4
240
1485
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
12.3
735
5826
H16.9
ICD-10 Finland
Keratitis, unspecified
3.7
12.2
38
104
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
5.2
12.2
25
49
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
37.8
12.2
15
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.8
12.1
181
1038
S18
ICPC
Laceration/cut
1.4
12.1
775
6221
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
12.0
958
7994
CS2P4
NOMESCO Finland
Optic nerve head imaging
5.7
12.0
22
39
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
11.8
621
4801
N03AX16
ATC
[U] pregabalin
1.5
11.7
380
2666
A02BC05
ATC
esomeprazole; systemic
1.4
11.7
687
5419
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
11.6
701
5553
A04
ICPC
Weakness/tiredness general
1.6
11.6
275
1792
J01FF01
ATC
clindamycin; systemic
1.5
11.5
446
3244
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
11.5
633
4927
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
11.5
224
1386
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
11.5
259
1665
36907
ICD-8 Finland
Other inflammatory diseases of eye, Morbi inflammatori orbitae alii
+∞
11.5
11
*
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
11.5
11
*
36900
ICD-8 Finland
Other inflammatory diseases of eye, Abscessus orbitae
+∞
11.5
11
*
CBH25
NOMESCO Finland
Tarsorrhaphy
+∞
11.5
11
*
R01AD09
ATC
mometasone; nasal
1.4
11.4
790
6407
H44.5
ICD-10 Finland
Degenerated conditions of globe
35.2
11.3
14
*
H03BA02
ATC
propylthiouracil; oral
20.2
11.1
16
8
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
43.6
10.9
13
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
2.7
10.9
57
214
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
10.8
385
2750
114
Kela drug reimbursment
Glaucoma
1.9
10.7
133
718
R03BB04
ATC
tiotropium bromide; inhalant
1.8
10.7
156
888
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
10.7
83
376
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
10.5
381
2727
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
10.1
10.5
20
20
CAE00
NOMESCO Finland
Removal of implant from orbit
+∞
10.4
10
*
N06AX11
ATC
mirtazapine; oral
1.4
10.4
576
4475
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.1
10.4
42
137
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
10.3
133
727
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
10.7
10.3
19
18
E83.51
ICD-10 Finland
Hypocalcemia
4.9
10.3
22
45
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
10.3
232
1492
WX892
NOMESCO Finland
Monitored bed care
1.9
10.2
123
658
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
10.2
505
3840
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.3
10.2
38
118
R42
ICD-10 Finland
Dizziness and giddiness
1.5
10.1
367
2627
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
10.0
734
5967
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
4.8
10.0
22
46
H20.1
ICD-10 Finland
Chronic iridocyclitis
4.6
10.0
23
50
S01EE01
ATC
latanoprost; ophthalmic
2.1
10.0
98
487
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
40.3
10.0
12
*
Z97.0
ICD-10 Finland
Presence of artificial eye
40.3
10.0
12
*
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
9.9
123
665
J02AC01
ATC
fluconazole; systemic
1.4
9.9
695
5611
S01EC04
ATC
brinzolamide; ophthalmic
2.4
9.8
64
269
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
9.7
1252
11136
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.5
9.7
58
234
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
9.6
495
3782
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
9.6
159
939
C03CA01
ATC
furosemide; systemic
1.5
9.6
426
3168
ZX050
NOMESCO Finland
Stereotactic radiotherapy
5.0
9.6
20
40
H16.0
ICD-10 Finland
Corneal ulcer
2.1
9.6
85
407
R03BA02
ATC
budesonide; inhalant
1.5
9.5
302
2098
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
9.5
297
2059
R06.0
ICD-10 Finland
Dyspnoea
1.4
9.4
438
3284
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.5
9.4
60
249
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.2
9.4
77
357
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
9.4
247
1646
J01FA10
ATC
azithromycin; systemic
1.4
9.4
983
8431
CA1CD
NOMESCO Finland
Very extensive orbita CT
+∞
9.4
9
*
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
9.4
9
*
Z71.8
ICD-10 Finland
Other specified counselling
1.4
9.3
572
4507
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
9.6
9.3
18
19
R51.81
ICD-10 Finland
Facial pain NOS
2.7
9.3
48
180
J20
ICD-10 Finland
Acute bronchitis
1.7
9.1
177
1094
E06.3
ICD-10 Finland
Autoimmune thyroiditis
4.8
9.1
20
42
J32.4
ICD-10 Finland
Chronic pansinusitis
3.2
9.1
35
111
H04.2
ICD-10 Finland
Epiphora
11.5
9.1
16
14
A11CC02
ATC
dihydrotachysterol; oral
11.5
9.1
16
14
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.4
9.0
32
96
M79.6
ICD-10 Finland
Pain in limb
1.4
8.9
745
6156
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
8.9
82
399
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
4.9
8.8
19
39
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
8.8
177
1103
S01AD03
ATC
aciclovir; ophthalmic
2.5
8.8
54
221
R06AE07
ATC
cetirizine; oral
1.4
8.8
747
6185
L17
ICPC
Foot/toe symptom/complaint
1.4
8.7
505
3932
R74
ICPC
Upper respiratory infection acute
1.4
8.7
561
4445
A07AA02
ATC
nystatin; oral
2.0
8.6
95
493
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
4.4
8.6
21
48
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
8.6
315
2252
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
8.6
156
946
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
10.1
8.5
16
16
J01AA02
ATC
doxycycline; systemic
1.4
8.5
1331
12061
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
20.1
8.5
12
6
J01MA14
ATC
moxifloxacin; systemic
1.7
8.5
141
835
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
8.5
118
663
H04.19
ICD-10 Finland
Other disorders of lacrimal gland
90.5
8.4
9
*
CDC40
NOMESCO Finland
Evisceration of eye with insertion of prosthesis
90.5
8.4
9
*
J01.4
ICD-10 Finland
Acute pansinusitis
4.3
8.4
21
49
A02BC03
ATC
lansoprazole; oral
1.4
8.4
457
3515
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
8.4
281
1973
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
8.4
341
2489
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
4.5
8.4
20
45
H50.52
ICD-10 Finland
Exophoria
3.4
8.4
29
86
36902
ICD-8 Finland
Other inflammatory diseases of eye, Tenonitis
+∞
8.3
8
*
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
+∞
8.3
8
*
H05.3
ICD-10 Finland
Deformity of orbit
+∞
8.3
8
*
3761A
ICD-9 Finland
Disorders of the orbit, Chronic inflammatory disorders of orbit
+∞
8.3
8
*
CAE20
NOMESCO Finland
Revision of conjunctival sac with graft
+∞
8.3
8
*
CEA00
NOMESCO Finland
Biopsy of extraocular muscle
+∞
8.3
8
*
CBN20
NOMESCO Finland
Shortening of eyelid retractors
+∞
8.3
8
*
S01EE05
ATC
tafluprost; ophthalmic
2.3
8.3
59
258
D06
ICPC
Abdominal pain localized other
1.7
8.2
149
903
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
8.2
870
7414
S01GX09
ATC
olopatadine; ophthalmic
2.4
8.2
52
216
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
8.2
574
4600
H10
ICD-10 Finland
Conjunctivitis
1.8
8.2
122
700
H25.8
ICD-10 Finland
Other senile cataract
1.7
8.2
148
898
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
4.4
8.2
20
46
M25.5
ICD-10 Finland
Pain in joint
1.4
8.1
574
4602
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
2.9
8.1
38
135
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.1
670
5502
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.1
8.1
32
103
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
8.1
454
3506
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.2
8.1
66
306
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
8.1
142
854
R03AC02
ATC
salbutamol; inhalant
1.3
8.1
937
8086
EBA00
NOMESCO Finland
Extraction of tooth
1.4
8.0
596
4813
F03
ICPC
Eye discharge
1.8
8.0
112
629
R60.0
ICD-10 Finland
Localized oedema
1.6
8.0
193
1258
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
8.0
264
1846
ZXC95
NOMESCO Finland
Use of surgical navigator
3.5
8.0
27
79
A12AA04
ATC
calcium carbonate; oral
3.4
7.9
28
84
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
7.9
318
2315
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
7.8
645
5288
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.8
993
8662
H26.4
ICD-10 Finland
After-cataract
1.7
7.8
142
862
XCW10
NOMESCO Finland
Assessment of vision
3.4
7.8
27
80
A01AB09
ATC
miconazole; local oral
1.7
7.8
134
802
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
45.2
7.7
9
*
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
15.1
7.7
12
8
H57.8
ICD-10 Finland
Other specified disorders of eye and adnexa
15.1
7.7
12
8
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.0
7.7
33
112
R05
ICPC
Cough
1.4
7.6
413
3169
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
7.6
89
473
H25.1
ICD-10 Finland
Senile nuclear cataract
1.4
7.6
366
2752
N03AX12
ATC
[U] gabapentin; oral
1.5
7.6
249
1741
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.7
7.5
39
147
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.5
154
966
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.5
410
3151
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
3.6
7.4
24
68
F13
ICPC
Eye sensation abnormal
2.3
7.4
51
221
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
7.3
436
3393
H47.2
ICD-10 Finland
Optic atrophy
8.4
7.3
15
18
CBF99
NOMESCO Finland
Other operation for ectropion
+∞
7.3
7
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
7.3
7
*
C69.60
ICD-10 Finland
Malignant tumor in orbit without histology
+∞
7.3
7
*
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
+∞
7.3
7
*
CA1DM
NOMESCO Finland
Eye and orbita very extensive MRI examination with 3 Tesla magnet
+∞
7.3
7
*
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
2.4
7.3
46
191
S01AA01
ATC
chloramphenicol; ophthalmic
2.0
7.3
76
388
E0000UV, ,
ATC
1.3
7.3
671
5577
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
7.3
188
1247
SPAT1009
SPAT
Measurement of intraocular pressure
3.4
7.3
25
74
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.2
386
2950
G44.2
ICD-10 Finland
Tension-type headache
1.5
7.2
228
1580
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
7.2
307
2258
CDC00
NOMESCO Finland
Enucleation of eye
30.1
7.1
9
*
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
6.6
7.1
17
26
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
8.0
7.1
15
19
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
3.0
7.1
30
101
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
4.1
7.1
19
47
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
12.1
7.1
12
10
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
5.6
7.1
19
34
N05BA04
ATC
oxazepam; oral
1.4
7.1
416
3231
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
7.0
95
529
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
7.0
92
508
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
7.0
7.0
16
23
J32.1
ICD-10 Finland
Chronic frontal sinusitis
4.4
7.0
17
39
WW200
NOMESCO Finland
Immunization
2.4
7.0
44
183
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.0
767
6523
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
6.9
151
961
M03BX02
ATC
tizanidine; oral
1.3
6.9
1052
9333
J01DA01
ATC
[U] cefalexin
1.3
6.9
1014
8958
JN4BD
NOMESCO Finland
Extensive body CT
1.6
6.8
146
925
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.8
6.8
109
639
R4120
NOMESCO Finland
Occupational therapy
1.8
6.8
104
603
CAB10
NOMESCO Finland
Lateral orbitotomy with excision of lesion
40.2
6.8
8
*
R01AD08
ATC
fluticasone; nasal
1.3
6.7
461
3661
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.3
6.7
51
230
Z01.7
ICD-10 Finland
Laboratory examination
1.4
6.7
272
1980
S97
ICPC
Chronic ulcer skin
1.8
6.7
90
501
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.7
279
2042
M54.5
ICD-10 Finland
Low back pain
1.3
6.7
606
5013
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
6.6
135
845
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.4
6.6
43
181
D07AC01
ATC
betamethasone; topical
1.3
6.6
573
4706
L15
ICPC
Knee symptom/complaint
1.4
6.6
419
3288
H26.3
ICD-10 Finland
Drug-induced cataract
5.9
6.6
17
29
D01
ICPC
Abdominal pain/cramps general
1.5
6.6
201
1382
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
2.8
6.6
31
111
R03BA01
ATC
beclometasone; inhalant
1.5
6.6
218
1525
H54.4
ICD-10 Finland
Blindness, monocular
10.1
6.5
12
12
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
6.5
295
2190
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
6.5
364
2800
N06AX21
ATC
duloxetine; oral
1.5
6.5
196
1345
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.0
6.5
64
321
M05BA04
ATC
alendronic acid; oral
1.6
6.5
133
835
ZXD05
NOMESCO Finland
Urgent procedure
1.3
6.5
450
3580
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
6.5
107
634
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
6.4
158
1036
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
70.1
6.4
7
*
CAD00
NOMESCO Finland
Exenteration of orbit with use of graft or flap
70.1
6.4
7
*
3112
FHL
Orbitotomy (includes biopsy and removal of local tumor or foreign object)
70.1
6.4
7
*
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.4
436
3457
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.4
405
3176
L04AD01
ATC
ciclosporin; systemic
2.7
6.4
32
119
J34.1
ICD-10 Finland
Cyst and mucocele of nose and nasal sinus
2.8
6.3
30
108
K90.0
ICD-10 Finland
Coeliac disease
2.2
6.3
50
230
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.9
6.3
70
366
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
6.3
167
1115
H54.1
ICD-10 Finland
Severe visual impairment, binocular
18.1
6.3
9
5
G73.0*E05.9
ICD-10 Finland
Myasthenic syndromes in thyrotoxicosis [hyperthyroidism]
+∞
6.3
6
*
CBG10
NOMESCO Finland
Cryotherapy for trichiasis
+∞
6.3
6
*
H060, E050,
ICD-10 Finland
+∞
6.3
6
*
CAB50
NOMESCO Finland
Orbitotomy with removal of foreign body
+∞
6.3
6
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
6.2
222
1575
XCW12
NOMESCO Finland
Assessment of colour vision
26.8
6.2
8
*
R5599
NOMESCO Finland
Other rehabilitation service
2.2
6.2
47
212
S29
ICPC
Skin symptom/complaint other
1.4
6.2
317
2400
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.0
6.2
68
354
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
2.9
6.2
27
93
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
6.2
201
1402
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
6.2
152
998
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
3.2
6.2
23
72
N05BA01
ATC
diazepam; systemic, rectal
1.5
6.1
193
1337
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.6
6.1
33
128
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
8.6
6.1
12
14
Z01.2
ICD-10 Finland
Dental examination
1.3
6.0
769
6625
M54.3
ICD-10 Finland
Sciatica
1.8
6.0
93
540
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.9
6.0
68
358
C08CA01
ATC
amlodipine; oral
1.3
6.0
565
4682
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
6.0
838
7301
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
6.0
472
3817

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
610
1060
8.17
307.65
7.7
3.5
4.59
4.52
pmol/l
0.50
581
950
649
456
21.62
307.65
4.9
1.9
5.64
15.91
iu/l
0.41
424
195
325
1231
3.00
62.69
1.4
1.2
198.37
146.64
u/ml
1.34
146
476
1593
12710
3.10
56.85
12.5
4.5
15.47
14.72
pmol/l
27.52
1518
11799
1279
9232
2.31
56.46
12.2
9.6
4.11
4.03
e9/l
0.58
1123
8056
125
271
4.88
54.31
2.2
1.7
0.93
0.78
g/l
0.46
98
218
1143
7966
2.18
53.80
8.9
7.1
1.21
1.22
mmol/l
1.64
1010
6905
846
5304
2.12
51.97
7.5
6.2
—
—
—
0
0
1099
7696
2.09
49.06
7.9
6.3
27.85
28.25
%
0.61
1049
7327
1147
8178
2.10
48.53
7.8
6.1
0.58
0.56
e9/l
1.94
988
7056
1035
7107
2.06
48.53
7.7
6.5
1.21
1.21
mmol/l
0.87
989
6590
1147
8195
2.09
48.03
7.9
6.2
0.04
0.04
e9/l
0.84
988
7072
1073
7502
2.06
47.42
8.0
6.3
8.88
8.71
%
1.12
1021
7059
1162
8369
2.08
47.25
7.8
6.2
1.90
1.94
e9/l
0.51
1030
7408
1069
7484
2.04
46.81
8.1
6.3
0.70
0.69
%
0.58
1016
7022
1169
8467
2.07
46.42
8.1
6.4
0.20
0.19
e9/l
1.12
1025
7421
1067
7483
2.04
46.28
8.0
6.3
2.98
2.83
%
1.11
1014
7034
1071
7566
2.02
44.95
7.7
6.2
57.10
56.97
%
0.13
1030
7249
753
4782
1.98
42.09
5.3
4.1
7.40
7.40
ph
0.14
566
3430
80
153
5.42
40.03
1.7
1.4
6.37
6.64
g/l
0.26
62
113
80
153
5.42
40.03
1.7
1.4
0.32
0.39
g/l
1.05
63
113
80
153
5.42
40.03
1.7
1.4
2.88
2.97
g/l
0.15
62
111
80
154
5.39
39.75
1.7
1.4
—
—
—
0
0
834
5640
1.89
37.28
3.7
3.5
2.34
2.36
mmol/l
2.97
761
5146
427
2343
2.08
34.81
1.5
1.3
370.42
483.87
titre
1.36
96
507
1469
12163
2.10
33.23
10.7
8.1
78.18
78.99
u/l
0.28
1423
11544
153
551
2.94
31.48
1.5
1.2
—
—
—
0
0
263
1248
2.30
30.63
3.7
3.8
67.10
83.31
ng/l
3.04
234
1094
307
1577
2.14
29.32
2.7
2.1
360.76
378.39
nmol/l
0.91
287
1476
719
4898
1.78
29.30
7.6
6.1
—
—
—
0
0
169
667
2.69
29.23
2.0
1.4
16.86
11.63
iu/ml
—
5
15
1175
9223
1.78
28.91
5.5
5.0
6.54
6.62
mmol/l
0.70
1124
8718
1669
14774
2.64
28.69
13.7
5.5
1.74
1.89
mu/l
3.34
1595
13802
950
7037
1.74
28.55
5.5
5.0
35.66
35.93
g/l
0.83
897
6644
1424
11886
1.92
28.23
5.7
4.2
12.73
11.86
mm/h
1.41
1353
11162
995
7493
1.73
27.93
2.9
2.5
75.73
77.59
nmol/l
1.33
923
6828
122
414
3.09
27.82
1.9
2.3
11.75
12.44
mg/l
0.38
117
387
256
1268
2.19
26.67
3.7
2.7
9.98
10.71
g/l
1.85
238
1175
948
7195
1.67
24.55
12.9
11.0
0.00
0.00
e9/l
0.04
763
5895
128
494
2.71
23.06
1.3
1.2
94.14
33.39
u/ml
—
7
23
312
1783
1.91
21.62
2.1
1.7
—
—
—
0
0
508
3361
1.71
21.54
1.8
1.5
2.31
2.38
g/l
0.36
324
2123
104
382
2.83
20.58
1.2
1.2
56.76
47.15
u/ml
—
8
42
151
677
2.34
19.81
1.9
1.8
11.42
8.67
iu/ml
0.36
31
154
198
1008
2.08
18.96
2.0
1.8
1.25
1.37
g/l
0.39
186
935
312
1870
1.81
18.36
1.6
1.6
—
—
—
0
0
353
2196
1.75
18.29
2.3
2.0
—
—
—
0
0
604
4321
1.60
18.25
3.5
3.1
0.36
0.42
e6/l
0.24
424
3106
398
2569
1.70
18.04
1.6
1.7
—
—
—
0
0
1691
15580
2.28
17.57
20.7
14.8
22.56
22.80
mg/l
0.11
1454
12715
448
3007
1.65
17.42
1.9
1.9
—
—
—
0
0
1029
8395
1.52
16.64
7.2
6.6
10.78
11.19
umol/l
0.59
995
8022
874
6890
1.52
16.62
2.3
2.1
99.68
97.04
pmol/l
0.77
449
3593
398
2621
1.66
16.56
3.8
3.5
0.81
0.82
mmol/l
0.56
376
2490
110
464
2.46
16.52
1.3
1.2
15.91
13.45
u/ml
—
10
65
1220
10336
1.55
16.47
5.3
4.5
2284.78
1944.92
e6/l
—
9
144
558
4001
1.57
16.32
4.9
4.0
91.67
92.69
%
0.42
548
3912
670
5007
1.54
16.26
3.7
3.2
31.92
56.88
e6/l
1.36
491
3756
109
462
2.45
16.20
1.3
1.2
9.84
2.57
u/ml
—
7
38
754
5790
1.52
16.06
4.6
3.8
72.11
100.96
e6/l
0.83
513
3986
224
1261
1.89
16.00
1.4
1.5
—
—
—
0
0
455
3162
1.59
15.03
3.1
2.9
2.45
2.45
mmol/l
0.29
404
2847
560
4098
1.53
14.63
4.9
4.3
—
—
—
0
0
323
2082
1.67
14.40
5.7
5.8
1.04
1.04
mmol/l
0.00
299
1926
1253
10814
1.51
14.34
5.4
4.4
—
3.47
—
0
15
1033
8580
1.47
14.28
4.1
3.8
0.03
0.01
estimate
0.43
208
1691
38
93
4.15
14.22
1.1
1.1
1.33
1.70
nmol/l
—
9
14
54
170
3.24
14.02
3.9
4.8
31.22
71.03
u/ml
1.00
18
56
1015
8419
1.47
14.01
4.1
3.8
0.00
0.00
estimate
0.50
215
1757
125
599
2.17
13.96
3.4
2.6
3.01
2.95
g/l
0.21
119
550
810
6444
1.46
13.81
2.3
2.1
—
—
—
0
0
186
1040
1.88
13.51
3.3
2.5
—
—
—
0
0
420
2939
1.56
13.24
4.4
3.7
326.93
449.11
ng/l
0.43
325
2157
1021
8529
1.45
13.24
4.1
3.8
12.69
3.47
estimate
0.50
222
1801
637
4869
1.48
13.17
2.5
2.1
162.50
212.57
u/l
1.13
590
4625
451
3218
1.53
12.98
1.4
1.3
26.80
31.52
iu/ml
0.39
124
1004
215
1279
1.77
12.74
3.3
2.9
66.68
66.81
g/l
0.09
202
1180
1697
15910
2.05
12.73
23.6
17.3
3.94
3.96
mmol/l
3.13
1674
15580
1694
15878
2.03
12.62
23.3
17.2
139.69
139.71
mmol/l
0.11
1674
15584
1597
14708
1.72
12.52
7.0
6.1
39.13
39.00
mmol/mol
0.26
1519
13830
126
636
2.05
12.30
3.4
2.5
4.00
3.73
g/l
0.58
120
588
357
2444
1.57
12.29
3.3
2.9
3.63
3.09
e6/l
0.27
161
1150
126
637
2.05
12.25
3.4
2.5
7.78
7.44
g/l
1.15
120
588
126
637
2.05
12.25
3.4
2.5
4.28
4.27
g/l
0.07
120
588
222
1348
1.74
12.24
1.3
1.2
—
—
—
0
0
382
2664
1.55
12.10
3.2
2.8
1.28
1.09
e6/l
0.25
188
1369
548
4140
1.46
11.74
2.6
2.2
2.62
2.81
mg/l
1.44
495
3580
848
6950
1.41
11.58
14.6
12.9
1.22
1.21
inr
0.43
729
5734
74
308
2.46
11.49
1.9
2.0
5.09
5.17
mmol/24h
0.07
65
276
49
167
2.99
11.19
1.2
1.2
—
—
—
0
0
575
4420
1.44
11.12
1.7
1.7
20.54
20.59
nmol/l
0.03
494
3744
290
1936
1.59
11.03
1.8
1.4
—
—
—
0
0
404
2918
1.49
10.71
3.2
2.8
533.58
521.74
mosm/kgh2o
0.52
350
2551
259
1695
1.62
10.68
2.7
2.7
1.69
1.80
%
1.47
245
1519
413
3002
1.49
10.60
1.3
1.3
9.73
10.64
u/ml
0.10
133
1192
517
3933
1.44
10.46
1.5
1.3
1.31
1.66
u/ml
0.49
137
1078
459
3420
1.46
10.35
2.9
2.6
6.96
6.77
e6/l
0.09
409
3102
637
5039
1.41
10.32
2.8
2.6
57.10
75.69
u/l
0.61
601
4690
819
6767
1.38
10.21
3.7
3.3
6.18
6.22
ph
0.54
409
3888
655
5216
1.40
10.18
2.7
2.3
—
—
—
0
0
1234
10928
1.41
9.98
3.9
3.3
44.75
46.35
u/l
0.26
1184
10335
347
2465
1.50
9.90
2.6
2.5
2.37
2.35
g/l
0.27
323
2289
98
490
2.06
9.85
1.7
1.5
0.24
0.23
g/l
0.09
91
466
106
546
2.00
9.82
3.4
2.5
9.95
10.16
g/l
0.16
99
495
294
2038
1.53
9.38
3.3
3.1
5.03
4.76
e9/l
0.10
258
1803
926
7870
1.36
9.37
3.7
3.1
126.11
112.79
ug/l
0.60
876
7397
325
2320
1.49
8.99
2.6
2.2
29.44
29.31
s
0.12
309
2254
203
1308
1.62
8.87
2.9
2.7
69.91
70.30
e9/l
0.05
136
953
612
4908
1.37
8.81
3.5
3.1
—
—
—
0
0
185
1167
1.65
8.80
1.7
1.3
281.83
200.55
u/ml
0.59
178
1081
365
2676
1.46
8.79
2.7
2.5
13.49
13.35
umol/l
0.13
342
2503
687
5616
1.36
8.74
3.6
3.3
31.40
32.81
u/l
0.37
651
5314
507
3956
1.39
8.59
2.7
2.3
—
—
—
0
0
97
509
1.96
8.55
1.7
1.5
1.20
1.20
g/l
0.02
90
483
1606
15077
1.57
8.51
5.7
4.9
5.90
5.88
mmol/l
0.27
1509
13918
308
2202
1.48
8.41
1.2
1.2
—
—
—
0
0
1441
13247
1.43
8.41
26.9
18.4
13.68
13.59
%
2.19
1426
13072
166
1036
1.66
8.23
1.3
1.3
47.71
50.76
au/ml
—
10
75
82
414
2.03
8.07
2.6
3.3
1.54
2.04
index
0.48
43
219
212
1415
1.56
7.98
1.5
1.4
—
—
—
0
0
312
2259
1.46
7.96
2.8
2.6
22.19
22.88
%
0.43
292
2113
113
647
1.80
7.63
1.8
1.9
1.58
1.55
g/l
0.10
98
570
114
655
1.79
7.61
1.3
1.2
0.24
1.46
u/ml
—
10
43
877
7542
1.32
7.53
3.0
2.7
—
—
estimate
—
0
0
550
4428
1.35
7.47
2.9
3.1
1256.26
1103.57
ng/l
0.39
472
3749
147
913
1.66
7.43
2.0
1.8
—
—
—
0
0
145
901
1.66
7.32
8.7
10.5
24.69
24.34
mmol/l
0.68
139
886
173
1130
1.59
7.15
2.5
2.4
17.78
21.95
au/ml
0.28
13
133
245
1728
1.48
7.11
7.8
8.7
7.41
7.42
ph
0.49
140
951
262
1873
1.47
7.11
2.6
2.8
5.72
7.84
umol/l
3.13
225
1653
90
494
1.86
6.98
4.8
3.7
46.73
66.97
mg/l
0.53
73
430
1716
16487
1.77
6.96
16.9
11.7
25.53
25.77
u/l
0.25
1690
16054
1722
16576
1.78
6.73
26.3
19.1
73.66
73.96
umol/l
0.17
1708
16386
243
1730
1.47
6.72
7.9
8.7
12.58
12.63
kpa
0.04
228
1668
243
1730
1.47
6.72
7.9
8.7
5.18
5.10
kpa
0.61
230
1668
89
494
1.84
6.68
4.8
3.7
36.42
49.75
mg/l
0.74
73
431
218
1521
1.49
6.67
2.6
2.4
31.68
40.18
u/l
1.55
179
1291
67
339
2.01
6.61
1.6
1.7
—
—
—
0
0
239
1714
1.45
6.36
7.9
8.7
1.17
0.99
mmol/l
0.31
194
1422
81
445
1.86
6.29
4.7
3.4
1.23
2.81
ratio
1.18
42
255
321
2431
1.39
6.29
1.8
1.7
1080.32
1208.30
nmol/l
1.96
242
1844
56
273
2.08
6.13
1.4
1.3
—
10.40
—
0
5
252
1841
1.43
6.06
1.3
1.3
—
—
—
0
0
286
2146
1.40
5.91
2.2
2.4
196.57
113.77
ug/g
1.22
232
1726
160
1075
1.54
5.86
2.5
3.1
175.21
169.24
ng/l
0.07
139
984
790
6850
1.27
5.83
2.0
1.9
1.34
1.37
mmol/l
0.54
669
5814
28
102
2.77
5.80
1.9
1.5
5.31
6.55
u/l
0.82
22
91
680
5798
1.28
5.72
3.6
3.5
58.17
51.58
ng/l
0.10
433
3912
32
126
2.57
5.72
1.1
1.1
—
—
—
0
0
35
145
2.44
5.64
1.7
1.3
1.73
1.12
u/ml
0.22
26
75
33
133
2.51
5.63
1.1
1.1
—
—
—
0
0
28
105
2.69
5.51
6.1
6.5
5.58
38.72
ug/l
1.20
20
62
190
1346
1.46
5.39
8.9
9.1
—
—
—
0
0
460
3755
1.30
5.38
5.6
4.6
—
—
—
0
0
67
369
1.85
5.22
1.3
1.2
—
—
—
0
0
209
1518
1.43
5.19
3.9
3.5
2.21
1.80
mmol/l
0.91
174
1319
450
3680
1.30
5.17
2.0
1.8
1.19
1.18
mg/l
0.02
351
2826
197
1426
1.43
4.99
4.5
4.6
0.75
0.33
%
0.23
57
340
118
774
1.56
4.84
2.4
2.3
—
—
—
0
0
192
1393
1.42
4.80
4.5
4.2
0.90
0.66
%
0.46
60
405
212
1569
1.40
4.74
4.0
3.6
7.38
7.38
ph
0.57
121
878
637
5483
1.25
4.73
3.8
3.4
7.13
7.39
mmol/l
0.73
544
4675
274
2116
1.35
4.70
1.2
1.3
—
—
—
0
0
184
1331
1.43
4.68
7.4
7.7
9.32
9.27
mmol/l
0.04
173
1278
41
198
2.10
4.67
2.3
2.7
—
—
—
0
0
95
598
1.62
4.64
1.2
1.1
—
—
—
0
0
31
134
2.34
4.60
1.2
1.1
—
—
—
0
0
39
189
2.09
4.42
1.2
1.3
—
—
—
0
0
191
1408
1.40
4.37
4.5
4.4
0.06
0.12
%
1.07
53
364
39
191
2.06
4.31
2.5
2.8
—
—
—
0
0
60
345
1.76
4.13
1.5
1.5
—
—
—
0
0
57
323
1.79
4.12
4.9
3.9
—
—
—
0
0
188
1397
1.39
4.11
7.6
7.9
1.31
1.33
mmol/l
0.07
181
1371
482
4075
1.25
4.10
2.9
2.6
325.63
331.61
umol/l
0.68
433
3626
196
1469
1.37
4.07
4.5
4.4
0.98
1.04
%
0.13
59
425
1745
17041
1.65
3.99
33.6
22.7
258.91
256.31
e9/l
0.91
1714
16719
171
1259
1.40
3.96
3.7
3.8
1.23
1.23
mmol/l
0.10
154
1086
1745
17044
1.64
3.94
33.5
22.6
91.10
90.97
fl
0.59
1733
16879
1745
17047
1.64
3.90
33.5
22.6
30.26
30.26
pg
0.07
1733
16881
1745
17047
1.64
3.90
34.2
23.1
40.35
40.51
%
0.23
1733
16871
1745
17047
1.64
3.90
33.5
22.7
4.48
4.48
e12/l
0.05
1709
16675
53
300
1.79
3.86
1.1
1.1
0.79
1.84
u/ml
1.01
33
153
1745
17050
1.63
3.86
33.6
22.7
6.86
6.69
e9/l
1.52
1710
16671
59
345
1.73
3.85
1.3
1.4
—
—
—
0
0
206
1572
1.35
3.82
3.9
3.5
5.76
5.81
kpa
0.38
192
1523
1745
17053
1.63
3.81
33.8
22.8
134.31
134.64
g/l
0.47
1734
16887
122
851
1.46
3.80
10.6
12.0
15.68
15.99
%
0.54
116
819
200
1522
1.35
3.78
8.6
9.2
95.86
95.86
%
0.00
192
1474
14
44
3.20
3.78
1.0
1.4
—
—
—
0
0
70
436
1.63
3.63
1.5
1.4
12.50
10.58
u/l
0.43
52
357
29
139
2.10
3.44
2.2
2.0
38.73
41.06
%
0.34
29
139
14
47
2.99
3.41
1.1
1.1
—
—
—
0
0
14
47
2.99
3.41
1.1
1.1
—
—
—
0
0
14
47
2.99
3.41
1.1
1.1
—
—
—
0
0
35
181
1.95
3.39
1.4
1.2
—
—
—
0
0
119
847
1.43
3.37
1.3
1.2
—
—
—
0
0
27
127
2.14
3.36
1.3
1.1
62.86
147.14
titre
—
7
21
35
182
1.94
3.34
1.5
1.6
—
—
—
0
0
90
611
1.50
3.25
1.6
1.6
18.44
13.17
u/ml
0.53
17
140
43
242
1.80
3.24
1.1
1.1
1.46
3.56
u/ml
1.13
24
102
58
357
1.65
3.19
3.1
3.2
57.14
58.47
%
0.30
58
357
204
1598
1.31
3.19
1.7
1.8
—
—
—
0
0
74
484
1.55
3.17
1.4
1.4
266.42
292.81
ug/g
0.52
45
275
53
319
1.68
3.17
1.1
1.1
1.43
4.28
u/ml
3.41
35
173
15
55
2.74
3.15
1.2
1.1
—
—
—
0
0
36
194
1.87
3.12
1.5
1.4
—
—
—
0
0
36
194
1.87
3.12
1.5
1.4
—
—
—
0
0
36
194
1.87
3.12
1.5
1.4
—
—
—
0
0
36
194
1.87
3.12
1.5
1.4
—
—
—
0
0
53
322
1.67
3.07
1.4
1.4
156.87
147.63
au/ml
0.26
15
100
25
119
2.12
3.04
1.2
1.1
308.84
249.19
mg/l
0.52
19
100
22
100
2.21
3.00
3.1
3.1
74.36
317.04
nmol/l
0.61
22
100
186
1452
1.31
2.99
9.2
9.5
120.18
121.07
g/l
0.24
180
1418
576
5103
1.19
2.91
3.7
3.5
44.10
46.50
mg/l
0.09
368
3176
29
149
1.96
2.90
5.5
3.1
59.86
55.70
%
0.60
29
138
91
635
1.46
2.90
2.5
2.1
20.85
20.79
s
0.04
84
567
196
1550
1.30
2.87
2.4
2.3
0.21
0.21
g/l
0.08
181
1454
67
441
1.54
2.83
5.7
8.1
1.39
1.29
mmol/l
0.42
60
386
167
1296
1.32
2.81
5.1
3.8
—
—
—
0
0
8
18
4.46
2.79
1.5
3.7
—
—
—
0
0
80
549
1.48
2.78
2.4
2.2
143.76
382.94
ug/l
2.06
74
519
584
5198
1.18
2.77
4.3
4.1
8.82
8.14
mg/mmol
0.11
352
3177
50
309
1.64
2.75
1.1
1.1
0.73
1.58
u/ml
0.77
31
135
187
1481
1.29
2.72
6.4
4.0
7.38
7.36
ph
0.89
153
1060
63
414
1.54
2.69
2.0
1.8
—
—
—
0
0
83
579
1.45
2.67
1.8
1.7
289.35
289.95
mu/l
0.01
76
524
37
213
1.75
2.64
1.1
1.2
—
—
—
0
0
25
127
1.98
2.60
1.3
1.2
38.71
39.84
mg/l
0.06
16
105
144
1108
1.33
2.59
1.2
1.3
—
—
—
0
0
21
100
2.11
2.59
1.9
1.6
58.34
106.48
ng/l
3.84
21
100
44
268
1.66
2.57
1.1
1.1
1.91
2.00
u/ml
0.03
24
126
11
36
3.07
2.56
1.3
1.3
—
—
—
0
0
97
704
1.40
2.53
1.8
1.7
0.24
0.35
mg/l
1.61
47
320
65
437
1.51
2.52
1.1
1.2
—
—
—
0
0
64
429
1.51
2.52
1.1
1.2
—
—
—
0
0
10
31
3.24
2.51
1.3
1.0
—
—
—
0
0
43
264
1.64
2.45
2.3
2.4
—
—
—
0
0
524
4663
1.17
2.45
3.7
3.2
0.01
0.19
estimate
0.49
179
1404
13
52
2.51
2.36
1.1
1.7
115.92
607.60
nmol/24h
0.44
13
52
57
379
1.52
2.35
1.5
1.5
1118.87
1388.33
e6/l
0.09
45
294
1616
15729
1.25
2.34
6.1
5.6
2.77
2.77
mmol/l
0.05
1516
14711
50
323
1.56
2.34
1.8
3.1
36.00
33.65
umol/l
0.17
43
293
37
222
1.68
2.32
1.1
1.1
0.11
0.36
u/ml
0.97
16
80
15
65
2.32
2.31
1.3
2.0
—
—
—
0
0
120
917
1.33
2.29
1.5
1.4
27.01
29.22
iu/l
0.33
96
788
184
1490
1.26
2.27
1.9
2.1
0.02
0.03
estimate
0.01
41
313
14
60
2.34
2.22
1.8
2.0
41.17
40.98
g/l
0.05
14
60
64
442
1.46
2.21
1.2
1.1
2.28
7.63
eliau/ml
—
6
57
521
4674
1.16
2.17
1.5
1.5
—
—
—
0
0
1381
13272
1.17
2.16
28.4
19.0
331.62
331.93
g/l
0.66
1372
13198
100
751
1.35
2.16
2.0
2.2
0.00
1.02
estimate
0.51
34
249
22
115
1.92
2.16
1.0
1.1
—
—
—
0
0
55
373
1.49
2.09
1.5
1.5
47.41
14.96
e6/l
0.88
41
273
55
373
1.49
2.09
1.1
1.1
0.74
2.12
u/ml
1.58
33
205
25
138
1.82
2.09
1.0
1.3
—
—
—
0
0
250
2113
1.21
2.09
7.6
7.1
104.11
104.26
mmol/l
0.19
250
2113
74
532
1.41
2.08
1.3
1.3
—
—
—
0
0
16
75
2.14
2.08
2.3
3.4
169.82
197.14
umol/l
0.10
11
44
9
31
2.91
2.07
1.2
1.1
—
—
—
0
0
9
31
2.91
2.07
2.1
2.6
—
—
—
0
0
5
10
5.01
2.07
2.2
1.5
—
—
—
0
0
10
37
2.71
2.07
1.0
1.2
18.11
17.16
umol/l
—
10
30
517
4657
1.15
2.02
4.4
3.9
0.00
0.01
estimate
1.54
211
1669
21
111
1.90
2.01
1.4
1.4
34.38
26.57
umol/l
0.40
21
100
62
435
1.44
2.00
3.7
2.6
—
—
—
0
0
33
201
1.65
1.99
1.5
1.9
—
1977.14
—
0
7
30
178
1.70
1.99
1.5
1.8
—
—
—
0
0
18
91
1.99
1.95
1.3
1.1
—
—
—
0
0
32
195
1.65
1.93
2.2
2.1
5.54
5.31
umol/l
0.05
21
144
8
27
2.97
1.93
2.1
2.0
—
—
—
0
0
25
142
1.77
1.93
1.4
1.7
3.68
3.90
mg/l
0.14
25
137
701
6465
1.14
1.93
4.1
3.7
0.17
0.12
estimate
0.11
175
1447
15
71
2.12
1.92
1.7
1.8
—
—
—
0
0
46
307
1.51
1.91
2.0
1.9
—
—
—
0
0
19
99
1.93
1.90
1.6
1.2
0.52
0.58
ratio
—
8
60
124
980
1.28
1.90
2.8
2.3
12.52
12.78
nmol/l
0.12
113
892
15
72
2.09
1.86
1.1
1.3
123.93
173.16
mmol/24h
2.07
15
72
8
28
2.87
1.86
1.4
1.0
9.22
5.88
mg/g
—
8
28
74
544
1.38
1.86
2.6
3.8
1148.48
305.23
mg/l
0.81
46
237
124
983
1.28
1.86
5.6
3.6
7.41
7.42
ph
0.19
100
834
19
100
1.91
1.85
3.4
2.4
46.89
41.55
%
—
9
53
41
270
1.53
1.82
1.5
1.6
—
—
—
0
0
1593
15551
1.20
1.80
5.3
5.0
4.71
4.73
mmol/l
0.24
1497
14604
8
29
2.77
1.79
3.3
1.4
—
—
—
0
0
13
60
2.18
1.78
1.6
3.2
—
—
—
0
0
88
671
1.33
1.76
1.2
1.3
—
—
—
0
0
22
124
1.78
1.76
3.3
2.4
26.35
29.42
mg/l
0.14
17
86
84
638
1.33
1.73
2.0
2.0
—
—
—
0
0
44
299
1.48
1.71
7.1
10.2
11.13
11.39
mmol/l
0.21
38
265
76
570
1.35
1.71
1.2
1.3
173.85
221.95
miu/ml
0.57
33
276
44
300
1.48
1.68
7.1
10.2
105.84
105.06
mmol/l
0.60
38
266
1584
15472
1.19
1.68
5.2
4.9
1.46
1.50
mmol/l
2.75
1474
14440
84
642
1.32
1.67
2.0
1.9
—
—
—
0
0
124
998
1.26
1.67
10.8
10.1
1.50
1.29
%
1.12
124
991
84
644
1.32
1.64
2.0
1.9
—
—
—
0
0
83
636
1.32
1.63
2.0
1.9
—
—
—
0
0
30
190
1.59
1.60
2.8
2.4
—
—
—
0
0
78
594
1.33
1.60
2.0
2.0
—
—
—
0
0
11
50
2.21
1.57
2.4
2.6
—
—
—
0
0
35
232
1.52
1.55
1.5
2.1
—
8.17
—
0
6
104
828
1.27
1.55
1.2
1.1
58.00
108.21
titre
—
5
19
13
64
2.04
1.54
52.3
35.1
5.85
7.08
ug/l
1.76
13
57
59
434
1.37
1.52
1.1
1.1
—
—
—
0
0
33
490
0.67
1.52
10.1
9.1
—
—
—
0
0
123
1003
1.24
1.50
11.1
10.2
94.26
94.17
%
0.09
123
997
24
147
1.64
1.47
4.3
3.8
—
—
—
0
0
39
268
1.47
1.47
1.2
1.2
2.75
5.07
u/ml
1.02
28
110
44
310
1.43
1.46
1.4
1.2
—
—
—
0
0
9
38
2.37
1.45
3.0
1.9
—
—
—
0
0
213
1842
1.18
1.43
1.4
1.4
—
—
—
0
0
412
3742
1.13
1.40
4.0
4.0
1.01
1.42
kg/l
0.50
281
2509
35
238
1.48
1.40
1.1
1.1
1.88
3.35
eliau/ml
0.67
12
99
142
1186
1.21
1.40
2.2
2.3
6.05
7.51
ug/l
0.78
119
1070
115
1398
0.81
1.39
1.8
1.7
3.48
3.52
mmol/l
0.13
87
970
17
96
1.78
1.39
1.6
1.5
1.25
1.31
nmol/l
0.08
12
73
155
1312
1.20
1.34
3.4
3.0
4.61
4.50
kpa
0.36
147
1272
16
90
1.78
1.33
1.1
1.1
1681.63
1656.98
miu/ml
0.02
16
90
66
507
1.31
1.32
2.2
1.8
—
—
—
0
0
15
83
1.81
1.31
3.7
3.6
0.80
0.84
index
0.10
15
83
86
685
1.27
1.31
6.5
3.7
—
—
—
0
0
13
69
1.89
1.28
1.6
3.0
—
—
—
0
0
44
598
0.73
1.28
1.1
1.1
0.63
0.64
ratio
—
7
67
11
55
2.01
1.27
2.3
1.5
—
—
—
0
0
28
186
1.51
1.26
2.3
2.2
—
—
—
0
0
24
154
1.57
1.26
1.3
1.3
1338.85
1830.40
e6/l
0.45
13
102
42
303
1.40
1.26
1.1
1.1
21.18
13.98
au/ml
—
9
76
66
512
1.30
1.24
3.8
3.4
7.40
7.41
ph
0.88
66
507
29
195
1.50
1.24
2.6
1.9
32.17
32.22
pg
0.02
29
195
6
25
2.40
1.24
1.0
1.0
—
—
—
0
0
6
25
2.40
1.24
1.2
1.2
—
—
—
0
0
6
25
2.40
1.24
1.0
1.0
—
—
—
0
0
6
25
2.40
1.24
1.0
1.0
—
—
—
0
0
16
93
1.73
1.21
1.4
1.2
14.13
9.69
mm/h
0.65
16
93
21
132
1.60
1.20
1.0
1.4
—
—
—
0
0
40
289
1.39
1.20
1.3
1.1
—
—
—
0
0
6
26
2.31
1.18
18.0
3.8
47.33
40.81
umol/l
—
6
18
6
26
2.31
1.18
1.2
1.5
—
—
—
0
0
52
395
1.33
1.15
2.0
1.7
7496.85
12482.25
e6/l
0.93
40
274
8
39
2.06
1.15
2.0
1.3
—
—
—
0
0
37
266
1.40
1.15
1.4
1.2
—
—
—
0
0
162
1866
0.86
1.13
1.9
1.9
3.29
3.46
ratio
1.25
134
1438
14
80
1.76
1.13
1.1
1.2
—
13.50
—
0
10
23
151
1.53
1.11
1.7
1.2
—
—
—
0
0
43
320
1.35
1.10
1.0
1.1
—
—
—
0
0
50
647
0.77
1.07
1.2
1.1
1.60
1.56
g/l
0.43
50
647
107
900
1.20
1.03
7.4
7.5
24.03
24.48
mmol/l
0.60
101
861
52
665
0.78
1.03
1.3
1.2
0.94
0.89
g/l
0.57
52
665
74
601
1.24
1.01
2.1
1.9
0.71
1.49
ug/l
1.47
63
531
38
282
1.35
1.00
1.1
1.0
—
—
—
0
0
20
131
1.53
1.00
1.3
1.3
31393.13
36339.48
e6/l
—
8
69
10
54
1.86
0.96
1.0
1.1
—
—
—
0
0
21
141
1.50
0.95
3.9
3.3
12.20
11.17
index
0.31
15
83
44
338
1.31
0.94
1.3
1.3
237.77
249.47
u/ml
0.09
22
201
42
321
1.32
0.93
1.0
1.1
—
—
—
0
0
115
985
1.18
0.93
3.1
2.9
130.57
129.24
g/l
0.29
108
952
13
208
0.62
0.92
1.4
1.7
—
—
—
0
0
43
332
1.30
0.90
3.9
3.6
—
—
—
0
0
66
539
1.23
0.88
6.8
3.9
24.73
25.03
mmol/l
0.33
61
506
18
119
1.52
0.88
1.0
1.1
0.53
1.12
u/ml
—
5
41
11
64
1.72
0.86
1.3
1.6
27.00
28.05
%
0.08
11
64
1501
14748
1.10
0.86
4.4
4.2
1.32
1.29
mmol/l
1.24
1382
13642
33
249
1.33
0.82
1.4
1.4
29.73
28.40
u/l
0.07
27
210
18
122
1.48
0.80
1.1
1.6
13.07
12.08
umol/l
0.18
18
114
8
48
1.67
0.78
1.1
1.2
28.50
27.62
s
—
8
48
616
6462
0.93
0.78
3.0
3.1
—
—
—
0
0
14
90
1.56
0.78
1.9
2.0
—
—
—
0
0
47
377
1.25
0.76
2.3
2.1
135.45
128.57
g/l
1.06
33
311
23
166
1.39
0.75
1.1
1.1
—
—
—
0
0
7
38
1.85
0.73
2.4
2.3
13.96
17.88
umol/l
—
7
38
22
159
1.39
0.72
2.6
2.0
—
—
—
0
0
350
3269
1.09
0.72
5.0
5.1
3.09
2.34
ug/l
0.43
312
2941
5
27
1.85
0.68
1.4
1.4
—
—
—
0
0
17
119
1.43
0.67
1.1
1.2
—
—
—
0
0
7
43
1.63
0.67
1.0
1.2
—
—
—
0
0
94
821
1.15
0.65
1.1
1.1
—
—
—
0
0
28
215
1.31
0.65
1.0
1.3
0.16
0.26
nmol/l
0.64
23
167
7
44
1.59
0.65
1.3
1.4
—
—
—
0
0
11
165
0.66
0.63
1.0
1.0
—
—
—
0
0
23
302
0.76
0.62
3.7
2.9
8.79
7.57
mmol/l
0.55
23
290
8
49
1.64
0.62
1.1
1.1
—
—
—
0
0
8
50
1.60
0.61
1.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.7
—
12.64
—
0
11
31
245
1.27
0.60
1.2
1.2
—
—
—
0
0
36
290
1.25
0.59
1.2
1.3
58.29
59.23
mmol/l
0.05
31
234
71
613
1.16
0.58
5.7
6.6
0.87
0.88
%
0.10
65
571
8
53
1.51
0.58
2.8
2.6
0.59
0.61
mmol/l
—
8
53
25
193
1.30
0.57
2.6
2.3
0.63
1.09
g/24h
0.62
14
109
14
98
1.43
0.56
1.1
1.1
—
—
—
0
0
77
674
1.15
0.54
5.6
6.2
1.64
1.54
%
0.34
69
634
37
303
1.23
0.54
4.9
3.8
2.89
2.63
mmol/l
0.31
31
210
40
331
1.21
0.53
1.4
1.6
—
—
—
0
0
50
423
1.19
0.53
1.4
1.5
66.41
59.40
ug/l
0.30
40
354
37
304
1.22
0.53
4.9
3.9
5.33
5.05
kpa
1.72
37
299
37
304
1.22
0.53
4.9
3.9
8.49
8.61
kpa
0.20
37
299
349
3305
1.07
0.52
1.8
1.7
40531985.39
47036005.31
pmol/l
0.08
301
2783
78
689
1.14
0.50
2.9
3.1
25.60
25.35
mmol/l
0.26
71
659
10
67
1.50
0.49
1.1
1.2
7.39
7.39
ph
—
5
47
26
207
1.26
0.49
1.0
1.3
—
—
nmol/l
—
0
0
142
1302
1.10
0.48
2.6
2.7
6.13
6.10
ph
0.18
107
868
21
164
1.28
0.46
1.1
1.1
—
—
—
0
0
7
49
1.43
0.46
6.7
4.4
—
—
—
0
0
5
82
0.61
0.45
2.0
1.4
146.60
394.95
u/l
—
5
77
48
412
1.17
0.45
2.1
1.8
42.96
40.93
nmol/l
0.18
48
399
18
138
1.31
0.45
1.3
1.4
—
—
—
0
0
67
591
1.14
0.45
2.3
2.1
916.53
6175.07
u/l
3.76
27
261
12
86
1.40
0.44
1.2
1.3
114.67
134.31
nmol/l
0.79
12
86
31
257
1.21
0.43
1.2
1.2
—
—
—
0
0
33
277
1.19
0.41
1.2
1.1
41.34
134.35
iu/ml
—
7
55
124
1141
1.09
0.41
4.5
3.2
—
—
—
0
0
55
483
1.14
0.40
2.9
2.6
—
—
—
0
0
5
34
1.47
0.40
4.0
3.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
260.38
—
0
8
0
18
0.00
0.40
0.0
1.2
—
1.91
—
0
18
10
71
1.41
0.39
2.8
1.6
—
—
—
0
0
34
288
1.18
0.39
1.7
1.5
0.36
0.36
nmol/l
0.00
28
222
21
169
1.25
0.38
1.8
1.7
37.73
61.38
%
1.67
15
106
17
134
1.27
0.37
1.3
1.3
—
—
—
0
0
37
318
1.17
0.37
1.4
1.5
1.32
1.29
mm
0.20
27
223
17
213
0.80
0.36
1.2
1.1
—
—
—
0
0
16
126
1.27
0.35
1.1
1.2
—
—
—
0
0
37
320
1.16
0.34
1.4
1.5
—
—
—
0
0
11
83
1.33
0.32
2.6
2.8
16.63
16.33
%
0.09
11
83
31
354
0.87
0.27
1.8
2.4
254.72
132.77
ug/min
0.21
17
217
204
1949
1.05
0.27
3.1
3.0
0.64
0.74
ug/l
1.66
132
1169
11
139
0.79
0.27
1.1
1.1
15.68
18.12
u/ml
—
5
63
18
150
1.20
0.26
1.8
1.4
13515.92
99048.43
e6/l
1.14
12
106
50
453
1.11
0.26
1.4
1.5
90.39
251.94
pmol/l
2.62
50
443
54
493
1.10
0.24
4.6
3.6
1.42
1.37
mmol/l
0.13
54
487
30
264
1.14
0.24
3.4
3.5
0.89
0.84
nmol/l
0.24
25
218
148
1552
0.95
0.23
1.3
1.3
—
—
—
0
0
5
42
1.19
0.21
1.6
1.5
0.68
0.51
e9/l
—
5
42
0
11
0.00
0.21
0.0
1.6
—
44.90
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
62.60
—
0
5
34
306
1.11
0.21
2.6
2.5
16.91
16.17
%
0.77
34
301
6
50
1.20
0.19
1.0
1.0
44.45
39.42
iu/ml
—
6
50
24
212
1.13
0.19
2.5
1.8
1.02
0.88
%
0.27
16
138
6
51
1.18
0.19
1.5
1.5
8.68
9.19
mmol/l
—
6
51
17
147
1.16
0.18
1.2
1.1
101.24
113.00
pmol/l
0.87
17
147
14
121
1.16
0.15
1.7
1.6
41.74
31.32
%
—
9
74
166
1608
1.04
0.15
3.4
4.5
180.56
22.88
ug/l
0.70
131
1309
7
87
0.80
0.14
1.4
1.3
—
—
—
0
0
77
733
1.05
0.14
1.5
1.6
1023.91
1022.04
mu/l
0.00
62
602
16
141
1.14
0.14
1.2
1.6
—
—
—
0
0
32
345
0.93
0.13
6.0
4.1
—
—
—
0
0
193
1882
1.03
0.12
5.4
4.9
32.16
32.32
%
0.07
140
1254
14
124
1.13
0.11
1.1
1.0
—
—
—
0
0
14
157
0.89
0.11
1.6
2.2
—
—
—
0
0
62
595
1.04
0.09
2.2
3.5
218.62
2526.42
u/ml
0.79
53
520
6
58
1.03
0.08
3.0
3.5
8.66
7.62
mg/l
—
6
46
7
64
1.09
0.08
1.4
2.0
0.00
0.00
estimate
—
7
64
8
75
1.07
0.07
1.9
1.2
140.35
162.90
pmol/l
—
8
75
70
716
0.98
0.04
5.4
4.1
36.94
36.91
°c
0.30
70
710
50
487
1.03
0.04
1.2
1.4
—
—
—
0
0
32
331
0.97
0.03
1.3
1.8
0.95
0.84
nmol/l
0.25
23
280
33
320
1.03
0.03
3.6
3.6
23.46
24.39
mg/l
0.07
26
218
74
730
1.01
0.02
1.9
1.9
—
—
—
0
0
12
114
1.05
0.00
1.6
1.5
71.33
78.49
umol/l
0.60
12
114
17
164
1.04
0.00
3.1
2.6
—
—
—
0
0
18
185
0.97
0.00
1.6
1.3
281.08
278.25
mosm/kgh2o
0.22
12
140
22
225
0.98
0.00
1.8
1.8
1.48
1.63
mmol/l
0.47
22
219
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
385.89
—
0
9
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
19
190
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
53
0.94
-0.00
2.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.42
—
0
5
6
62
0.97
-0.00
1.0
1.0
123.88
186.83
iu/ml
—
6
62
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
9
89
1.01
-0.00
1.7
2.6
11.32
9.36
mmol/l
—
9
89
0
6
0.00
-0.00
0.0
1.2
—
31.15
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
257.67
—
0
6
7
75
0.93
-0.00
1.1
1.5
37.73
31.45
nmol/l
—
7
61

Mortality – FinRegistry

Association

Association between endpoint H7_ORBIT and mortality.

Females

Parameter HR [95% CI] p-value
H7_ORBIT 1.329 [1.18, 1.49] < 0.001
Birth year 0.993 [0.98, 1.0] 0.125

During the follow-up period (1.1.1998 — 31.12.2019), 737 out of 5877 females with H7_ORBIT died.

Males

Parameter HR [95% CI] p-value
H7_ORBIT 1.431 [1.24, 1.65] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 575 out of 3310 males with H7_ORBIT died.

Mortality risk

Mortality risk for people of age

years, who have H7_ORBIT.

N-year risk Females Males
1 0.149% 0.331%
5 0.859% 1.848%
10 1.888% 4.304%
15 3.475% 8.147%
20 6.072% 13.883%

Relationships between endpoints

Index endpoint: H7_ORBIT – Disorders of orbit

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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