No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditions
|
1023 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1005 |
4. Check minimum number of eventsNone |
1005 |
5. Include endpointsNone |
1005 |
6. Filter based on genotype QC (FinnGen only) |
919 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
Graves ophthalmopathy
based on the number of shared cases.
Similar with more cases:
- Disorders of lacrimal system and orbit in diseases classified elsewhere
- Disorders of orbit
- Thyrotoxicosis
- Disorders of thyroid, IBD co-morbidities
- Disorders of eyelid, lacrimal system and orbit
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4440 | 3590 | 832 |
| Only index persons | 4309 | 3510 | 799 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.02 |
| Only index persons | 0.11 | 0.13 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 50.59 | 50.50 | 51.24 |
| Only index persons | 50.44 | 50.39 | 50.67 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 919 | 753 | 166 |
| Unadjusted period prevalence (%) | 0.23 | 0.27 | 0.08 |
| Median age at first event (years) | 51.87 | 51.37 | 54.11 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 960
- Matched controls
- 9600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
307.7
855
*
H03AA01
ATC
levothyroxine sodium; systemic
21.2
307.7
799
1819
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
40.6
307.7
273
93
H03BB01
ATC
carbimazole; oral
185.4
307.7
772
208
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
86.7
307.7
516
127
BAA60
NOMESCO Finland
Total thyroidectomy
42.9
307.7
347
125
104
Kela drug reimbursment
Thyroid insufficiency
14.3
307.7
383
425
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
497.3
307.7
839
132
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
157.6
296.4
147
11
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
44.5
254.7
154
41
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
43.5
253.1
154
42
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
238.8
219
*
H062, E050,
ICD-10 Finland
+∞
236.5
217
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
61.9
179.0
100
18
H50.2
ICD-10 Finland
Vertical strabismus
45.7
159.6
95
23
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
6.7
148.3
757
3431
H53.2
ICD-10 Finland
Diplopia
12.2
145.7
156
150
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.8
124.7
615
2587
C07AA05
ATC
propranolol; systemic
4.4
108.0
425
1478
H05.2
ICD-10 Finland
Exophthalmic conditions
181.6
95.1
98
6
XCK00
NOMESCO Finland
Perimetry
6.9
94.4
162
275
T85
ICPC
Hyperthyroidism/thyrotoxicosis
26.9
90.8
63
25
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.9
82.9
220
554
E03.89
ICD-10 Finland
Other specified hypothyroidism
7.0
80.0
132
214
T86
ICPC
Hypothyroidism/myxoedema
5.9
69.3
136
261
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
11.2
65.5
71
68
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.6
63.6
276
976
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
12.8
59.6
59
49
H02AB06
ATC
prednisolone; systemic
3.0
58.5
617
3584
ZX120
NOMESCO Finland
Intravenous
4.2
57.1
178
499
H50.0
ICD-10 Finland
Convergent concomitant strabismus
18.8
56.3
45
25
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
54.7
52
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.8
54.6
136
320
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
52.2
288
1162
CA1AD
NOMESCO Finland
Orbita CT
137.3
49.3
52
*
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
48.3
46
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
64.4
42.6
49
8
XCD10
NOMESCO Finland
Electrophysiological examination of eye
7.7
42.4
61
84
H04.10
ICD-10 Finland
Dry eye syndrome
3.0
40.5
217
848
E03
ICD-10 Finland
Other hypothyroidism
3.8
40.1
133
385
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
10.4
37.4
42
42
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
197.6
37.1
38
*
ZXA10
NOMESCO Finland
Bilateral
2.7
36.9
253
1122
H50.8
ICD-10 Finland
Other specified strabismus
131.7
36.0
38
*
CAC44
NOMESCO Finland
Combined decompression of orbit
359.8
35.2
35
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
7.9
35.1
49
65
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
32.9
280
1369
CAC20
NOMESCO Finland
Lateral decompression of orbit
+∞
31.4
30
*
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
30.4
29
*
A02BC02
ATC
pantoprazole; systemic
2.5
29.8
749
5662
C07AB07
ATC
bisoprolol; oral
2.1
28.8
505
3286
WF099
NOMESCO Finland
Other radiotherapy
27.0
28.6
39
15
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.4
28.6
75
182
L04AX03
ATC
methotrexate; systemic
2.9
28.0
154
603
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
31.1
27.4
36
12
H02AB07
ATC
prednisone; oral
2.6
26.3
185
819
L04AA06
ATC
mycophenolic acid; systemic
6.5
25.0
41
65
CS494
NOMESCO Finland
Other visual field testing
5.2
24.7
52
105
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
5.1
23.9
51
104
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
128.2
23.7
25
*
A11CC03
ATC
alfacalcidol; systemic
5.8
23.2
43
77
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
30.9
22.9
30
10
XCK10
NOMESCO Finland
Photography of fundus of eye
2.9
22.8
118
445
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.1
22.6
64
164
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
22.2
287
1630
2AB04, ,
NOMESCO Finland
39.7
21.8
27
7
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
28.8
21.0
28
10
Z3231
NOMESCO Finland
Registered nurse
2.0
20.3
293
1724
CEW99
NOMESCO Finland
Other operation on extraocular muscle
58.8
20.0
23
*
WX402
NOMESCO Finland
General anaesthesia
2.0
19.9
264
1504
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
19.9
19
*
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
19.9
19
*
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
15.7
19.8
32
21
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
7.9
19.6
27
35
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
19.6
386
2515
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
3.0
19.2
87
304
N05CF01
ATC
zopiclone; oral
1.9
18.8
350
2231
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
28.5
18.8
25
9
E05.5
ICD-10 Finland
Thyroid crisis or storm
71.3
18.8
21
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
18.4
400
2676
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.8
18.4
58
161
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.5
18.2
121
516
E05.89
ICD-10 Finland
Other thyrotoxicosis
33.6
18.0
23
7
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
14.2
17.4
29
21
H57.1
ICD-10 Finland
Ocular pain
3.2
16.7
68
223
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
12.4
16.4
29
24
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.1
16.0
34
69
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
18.1
15.2
23
13
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
15.0
459
3332
WF002
NOMESCO Finland
Radical radiotherapy
3.3
15.0
58
184
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
6.5
14.6
24
38
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.7
13.9
80
318
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.0
13.8
166
901
CE2W4
NOMESCO Finland
Eye movement mapping
34.6
13.5
17
5
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
14.3
12.8
21
15
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
12.7
326
2230
S01KA02
ATC
hypromellose; ophthalmic
4.4
12.5
31
72
H02AB09
ATC
hydrocortisone; systemic
3.9
12.4
36
94
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
47.3
11.9
14
*
H03BA02
ATC
propylthiouracil; oral
30.4
11.7
15
5
1XC02, ,
NOMESCO Finland
9.8
11.3
22
23
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
11.1
83
373
106
Kela drug reimbursment
Hypoparathyroidism
14.1
11.0
18
13
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.6
10.8
35
99
S01GX01
ATC
cromoglicic acid; ophthalmic
1.7
10.4
235
1540
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
111.2
10.4
11
*
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
10.7
10.3
19
18
XCH00
NOMESCO Finland
Eye pressure measurement
2.7
10.1
54
207
CA1BD
NOMESCO Finland
Extensive orbita CT
26.3
9.8
13
5
WX002
NOMESCO Finland
Sedation and analgesia
1.7
9.7
187
1171
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
13.5
9.7
16
12
N07BA03
ATC
varenicline; oral
2.5
9.6
61
254
H40.0
ICD-10 Finland
Glaucoma suspect
2.2
9.5
87
425
F29
ICPC
Eye symptom/complaint other
1.9
9.4
122
677
Z2221
NOMESCO Finland
Medical doctor
1.6
9.4
273
1903
H02.4
ICD-10 Finland
Ptosis of eyelid
3.0
9.3
41
141
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
7.8
9.2
20
26
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
8.4
9.1
19
23
WX892
NOMESCO Finland
Monitored bed care
2.3
8.8
70
323
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
8.8
213
1416
ZX090
NOMESCO Finland
Other technic of radiotherapy
3.1
8.8
36
119
H50.52
ICD-10 Finland
Exophoria
4.3
8.7
22
52
H02.8
ICD-10 Finland
Other specified disorders of eyelid
10.1
8.5
16
16
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.2
8.5
74
354
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.3
8.3
31
97
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.8
8.1
118
679
ZXE00
NOMESCO Finland
One hour or less
1.5
8.1
368
2815
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.0
8.0
83
425
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
22.2
8.0
11
5
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
7.3
8.0
18
25
A11CC02
ATC
dihydrotachysterol; oral
13.2
7.9
13
10
CD2S4
NOMESCO Finland
Photography of eye
8.5
7.8
16
19
107
Kela drug reimbursment
Pernicious anaemia
4.0
7.6
21
53
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
25.2
7.6
10
*
H01.0
ICD-10 Finland
Blepharitis
2.0
7.5
83
436
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.7
7.5
23
63
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
13.5
7.4
12
9
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
+∞
7.3
7
*
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
30.2
7.2
9
*
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
20.2
7.1
10
5
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
20.2
7.1
10
5
H50.1
ICD-10 Finland
Divergent concomitant strabismus
8.9
7.1
14
16
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
7.0
134
835
H02.3
ICD-10 Finland
Blepharochalasis
2.0
6.9
73
378
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
11.0
6.8
12
11
ZX050
NOMESCO Finland
Stereotactic radiotherapy
7.2
6.7
15
21
Z01.7
ICD-10 Finland
Laboratory examination
1.6
6.7
169
1130
ZXC95
NOMESCO Finland
Use of surgical navigator
3.8
6.7
20
54
E83.51
ICD-10 Finland
Hypocalcemia
6.5
6.7
16
25
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
10.1
6.5
12
12
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.3
6.4
23
70
XCW12
NOMESCO Finland
Assessment of colour vision
70.3
6.4
7
*
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
70.3
6.4
7
*
H01CB02
ATC
octreotide; parenteral
14.4
6.4
10
7
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.3
6.4
48
217
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
6.4
272
2035
E06.3
ICD-10 Finland
Autoimmune thyroiditis
5.6
6.3
17
31
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
6.3
6
*
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
6.3
6
*
H060, E050,
ICD-10 Finland
+∞
6.3
6
*
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
26.9
6.2
8
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.1
6.2
25
82
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.2
403
3256
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
6.1
117
728
WX140
NOMESCO Finland
Parabulbar anesthesy
2.3
6.1
45
202
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.0
238
1752
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
528
294
38.69
307.65
5.7
2.0
6.08
3.87
iu/l
2.99
377
121
508
635
15.87
307.65
8.6
3.5
4.63
4.52
pmol/l
0.81
484
561
238
769
3.79
62.77
1.5
1.2
200.87
145.15
u/ml
1.30
115
313
943
7138
19.13
61.16
17.1
4.8
15.89
14.66
pmol/l
42.42
917
6624
658
4378
2.60
41.00
7.9
6.6
1.21
1.22
mmol/l
1.98
579
3779
593
3914
2.35
35.17
6.6
5.9
1.21
1.22
mmol/l
1.71
567
3608
178
720
2.81
30.55
2.9
3.6
53.52
80.16
ng/l
9.53
161
638
698
5130
2.32
29.45
10.1
9.7
3.87
3.98
e9/l
0.72
607
4503
944
8163
10.39
29.17
18.9
5.9
1.63
1.88
mu/l
4.36
919
7624
482
3167
2.05
25.81
3.3
3.4
2.33
2.36
mmol/l
5.15
435
2880
599
4313
2.03
24.21
3.0
2.5
76.69
78.47
nmol/l
0.86
560
3926
812
6733
2.34
20.32
9.6
8.0
76.55
77.88
u/l
0.37
792
6390
786
6569
2.08
17.11
5.2
4.5
11.48
11.80
mm/h
0.28
749
6142
173
910
2.10
15.84
2.4
2.1
372.75
379.73
nmol/l
0.19
162
847
626
5000
1.72
13.99
4.7
4.5
6.39
6.56
mmol/l
1.52
601
4734
53
175
3.15
12.87
2.1
2.7
5.07
7.71
pmol/l
3.23
53
175
514
3953
1.65
12.73
11.7
10.9
0.00
0.00
e9/l
0.31
402
3251
496
3856
1.59
11.19
4.2
4.5
36.03
36.11
g/l
0.12
464
3646
36
104
3.56
10.80
4.3
5.6
38.98
48.14
u/ml
0.17
12
35
888
8098
2.29
10.71
6.8
6.1
38.68
38.81
mmol/mol
0.18
849
7620
290
2008
1.64
10.42
1.5
1.5
2.21
2.34
g/l
0.64
172
1225
926
8632
3.05
10.20
19.5
16.6
139.81
139.72
mmol/l
0.51
915
8460
927
8647
3.10
10.19
19.8
16.7
3.92
3.94
mmol/l
2.51
914
8456
318
2314
1.56
9.03
1.4
1.3
1.25
1.72
u/ml
0.47
82
622
909
8457
2.41
8.97
16.2
14.7
21.92
21.49
mg/l
0.15
756
6904
891
8266
2.08
8.15
5.7
5.1
5.82
5.85
mmol/l
0.26
853
7658
58
257
2.34
8.03
1.2
1.2
55.10
53.18
u/ml
—
6
29
476
3858
1.46
7.69
2.3
2.1
102.61
97.85
pmol/l
1.23
243
1932
311
2319
1.50
7.64
3.1
3.1
0.24
0.40
e6/l
1.50
213
1679
191
1290
1.60
7.29
3.0
3.0
4.20
3.43
e6/l
0.28
88
587
888
8277
1.97
7.25
16.4
14.1
83.79
82.60
ml/min/173m2
1.10
823
7628
51
225
2.34
7.15
2.2
3.0
1.73
2.21
index
0.27
26
113
939
8973
3.12
6.88
16.3
12.0
23.85
25.12
u/l
2.03
928
8745
208
1461
1.54
6.64
3.2
3.0
0.82
0.82
mmol/l
0.06
192
1384
24
75
3.26
6.45
1.1
1.1
1.13
0.89
nmol/l
—
7
8
939
8995
3.01
6.41
22.3
18.9
70.93
71.81
umol/l
0.54
930
8894
201
1419
1.53
6.24
2.9
2.8
1.62
1.16
e6/l
0.38
99
718
680
6019
1.44
6.14
3.7
3.2
35.89
44.04
u/l
3.18
658
5686
163
1108
1.57
5.98
4.7
5.0
1.07
1.04
mmol/l
0.66
147
1022
217
1577
1.49
5.83
4.4
3.6
204.91
275.98
ng/l
0.19
164
1142
20
60
3.38
5.74
6.3
8.0
6.96
284.44
ug/l
0.53
14
41
340
2696
1.40
5.69
3.2
3.2
35.08
72.75
e6/l
0.72
242
2046
76
428
1.84
5.61
1.6
2.0
8.47
7.61
iu/ml
0.07
15
102
239
1783
1.45
5.59
2.8
2.7
2.43
2.45
mmol/l
2.39
208
1606
235
1766
1.44
5.26
1.4
1.3
7.20
11.62
u/ml
0.56
73
694
785
7219
1.48
5.16
24.9
18.2
13.58
13.57
%
0.07
780
7126
282
2206
1.39
4.99
4.3
3.6
92.83
94.87
%
0.73
277
2150
113
736
1.61
4.96
2.2
3.1
10.14
10.51
g/l
0.41
104
689
145
1004
1.52
4.87
2.1
2.5
6.07
6.86
umol/l
0.47
122
885
127
854
1.56
4.87
2.2
2.3
29.30
40.69
u/l
2.64
105
715
88
541
1.69
4.84
2.8
2.9
150.74
161.56
ng/l
0.13
78
499
551
4801
1.35
4.83
3.7
3.9
0.04
0.02
estimate
0.21
106
922
546
4752
1.35
4.81
3.6
3.9
0.00
6.54
estimate
1.33
109
982
541
4703
1.34
4.80
3.6
3.9
0.00
0.00
estimate
0.50
107
956
283
2243
1.37
4.56
2.7
2.2
2.44
2.84
mg/l
3.08
252
1925
12
23
5.27
4.46
1.6
1.3
0.43
0.36
ug/l
—
7
17
69
406
1.75
4.45
2.1
2.2
42.19
40.25
u/l
0.34
62
368
246
1929
1.37
4.20
1.4
1.3
27.63
29.73
iu/ml
0.10
73
603
39
194
2.05
4.18
2.4
2.2
4.78
5.13
mmol/24h
0.35
33
170
265
2112
1.35
4.06
2.2
2.2
—
—
—
0
0
53
299
1.82
3.96
1.5
1.5
0.23
0.08
iu/ml
—
8
41
501
4398
1.29
3.74
3.9
3.1
92.58
103.67
ug/l
0.96
474
4139
302
2503
1.30
3.44
1.6
1.7
21.00
21.22
nmol/l
0.10
263
2106
523
4647
1.28
3.42
5.9
6.2
11.17
10.69
umol/l
0.36
506
4432
51
299
1.75
3.39
1.1
2.1
0.63
0.88
g/l
0.15
46
268
23
101
2.31
3.38
1.3
1.2
—
—
—
0
0
441
3844
1.27
3.35
2.0
1.9
1.28
1.34
mmol/l
1.29
382
3266
944
9218
2.44
3.33
30.2
22.8
262.11
258.44
e9/l
1.09
928
9059
31
155
2.03
3.33
1.1
1.1
—
18.00
—
0
7
944
9220
2.43
3.29
30.1
22.7
91.05
91.01
fl
0.09
938
9131
944
9221
2.43
3.27
30.7
23.1
40.61
40.14
%
2.76
938
9129
944
9221
2.43
3.27
30.1
22.8
4.50
4.46
e12/l
2.95
926
9032
944
9224
2.41
3.21
30.3
22.9
135.17
133.86
g/l
2.74
939
9134
15
56
2.71
3.07
2.3
1.8
—
—
—
0
0
15
57
2.66
2.97
1.1
1.3
38.95
28.73
umol/l
0.40
15
51
87
603
1.49
2.95
1.6
1.9
—
—
—
0
0
180
1420
1.33
2.88
2.6
2.4
14.55
13.26
umol/l
1.52
170
1322
611
5597
1.25
2.82
3.1
3.2
—
—
—
0
0
52
326
1.63
2.75
1.1
2.0
3.02
2.93
g/l
0.25
47
302
97
698
1.43
2.73
3.2
3.6
1.22
1.23
mmol/l
1.20
90
593
462
4118
1.23
2.69
2.7
2.6
—
—
estimate
—
0
0
169
1336
1.32
2.67
1.7
1.7
1070.63
1188.92
nmol/l
1.10
125
987
69
467
1.51
2.64
1.5
1.7
—
—
—
0
0
226
1867
1.28
2.56
2.4
2.6
6.38
7.07
e6/l
0.27
197
1699
47
296
1.62
2.46
1.1
2.0
9.63
10.58
g/l
1.26
42
270
164
1308
1.31
2.43
2.5
2.4
2.43
2.36
g/l
0.89
153
1217
352
3090
1.22
2.27
3.4
3.0
28.56
30.26
u/l
0.63
335
2933
23
120
1.94
2.27
1.2
1.3
—
—
—
0
0
52
344
1.54
2.24
1.1
2.0
4.12
3.77
g/l
0.30
47
320
52
344
1.54
2.24
1.1
2.0
4.25
4.34
g/l
0.39
47
320
52
344
1.54
2.24
1.1
2.0
7.74
7.42
g/l
0.78
47
320
309
2681
1.22
2.23
2.3
2.1
152.37
181.38
u/l
0.35
286
2550
26
143
1.84
2.20
1.7
1.6
—
—
—
0
0
22
398
0.54
2.18
4.5
3.5
56.86
48.64
%
0.69
22
390
154
1237
1.29
2.17
2.1
2.3
160.06
110.11
ug/g
0.44
124
977
116
896
1.34
2.16
3.2
4.4
231.00
247.37
u/l
0.55
109
859
53
357
1.51
2.12
1.5
1.8
—
—
—
0
0
13
56
2.34
2.05
1.5
1.7
46.46
106.94
ng/l
3.33
13
56
25
140
1.81
2.02
1.0
1.0
2.23
1.88
eliau/ml
—
7
59
92
694
1.36
2.01
1.6
2.8
66.32
67.36
g/l
0.70
83
645
19
97
1.98
2.01
1.6
1.3
0.44
0.77
u/ml
0.22
11
46
410
3689
1.19
1.98
11.7
12.0
1.19
1.18
inr
0.26
350
3044
166
1362
1.26
1.98
2.0
1.9
—
—
—
0
0
69
498
1.42
1.96
1.0
1.0
—
—
—
0
0
68
492
1.41
1.91
1.4
1.8
—
—
—
0
0
127
1012
1.29
1.91
1.9
1.8
—
—
—
0
0
80
597
1.37
1.88
1.3
1.3
71.52
37.99
au/ml
—
6
45
6
17
3.54
1.84
4.2
1.9
260.67
286.94
u/l
—
6
17
6
17
3.54
1.84
1.0
1.2
—
—
—
0
0
5
12
4.18
1.82
2.0
1.8
—
—
—
0
0
80
601
1.36
1.81
1.4
1.3
25.34
29.58
iu/l
0.60
64
521
880
8553
1.35
1.79
5.1
5.1
4.79
4.79
mmol/l
0.05
830
8030
240
2072
1.21
1.79
2.0
1.7
1.01
1.06
mg/l
0.08
184
1614
27
162
1.69
1.76
1.0
1.1
0.58
1.39
u/ml
0.71
16
76
146
1201
1.25
1.71
2.7
2.4
23.09
22.62
%
0.18
135
1126
56
769
0.71
1.71
1.7
1.8
3.49
3.50
mmol/l
0.01
41
543
17
89
1.93
1.70
1.5
1.6
—
—
—
0
0
41
276
1.51
1.69
1.3
1.4
281.88
297.35
ug/g
0.19
26
160
40
269
1.51
1.66
1.2
1.2
—
—
—
0
0
16
84
1.92
1.60
1.1
1.2
—
—
—
0
0
24
144
1.68
1.58
1.2
1.4
—
—
—
0
0
24
144
1.68
1.58
1.2
1.4
—
—
—
0
0
25
152
1.66
1.58
1.2
1.2
1.77
3.06
u/ml
0.42
13
49
23
137
1.70
1.56
1.0
1.1
0.42
3.44
u/ml
1.96
14
53
18
100
1.82
1.53
1.5
1.6
—
—
—
0
0
39
266
1.49
1.53
2.5
2.0
161.06
228.55
ug/l
0.50
34
249
17
93
1.84
1.52
1.1
1.1
—
—
—
0
0
109
880
1.27
1.51
8.0
7.3
1.18
1.04
mmol/l
0.14
88
741
16
86
1.88
1.51
1.1
1.2
—
—
—
0
0
887
8660
1.32
1.49
6.0
5.8
2.83
2.79
mmol/l
0.49
835
8105
9
37
2.45
1.48
1.3
1.9
67.89
49.65
ug/l
—
9
37
16
88
1.83
1.42
1.1
1.1
—
—
—
0
0
16
88
1.83
1.42
1.1
1.1
—
—
—
0
0
26
165
1.59
1.41
1.5
1.5
—
—
—
0
0
10
46
2.19
1.40
2.0
2.9
0.90
0.78
index
—
10
46
873
8517
1.28
1.38
5.1
5.0
1.52
1.54
mmol/l
0.51
819
7947
18
105
1.73
1.34
1.3
1.2
—
—
—
0
0
324
2937
1.16
1.32
3.1
3.3
7.00
7.23
mmol/l
0.38
281
2505
42
301
1.41
1.31
1.4
1.8
0.23
0.23
g/l
0.14
37
289
202
1767
1.18
1.30
1.6
1.6
—
—
—
0
0
82
653
1.28
1.29
2.5
2.5
15.35
23.38
au/ml
—
6
64
37
260
1.44
1.29
1.9
3.6
34.60
39.45
mg/l
0.39
28
224
10
48
2.09
1.28
1.5
1.2
15.90
9.54
mm/h
—
10
48
15
84
1.80
1.27
1.1
1.2
—
—
—
0
0
11
56
1.98
1.22
1.2
1.1
—
—
—
0
0
224
1991
1.16
1.18
1.4
1.5
—
—
—
0
0
44
327
1.36
1.14
1.7
1.8
1.41
1.48
g/l
0.19
35
289
35
250
1.42
1.14
1.4
1.6
67.27
60.69
ug/l
0.23
27
205
83
1013
0.80
1.13
1.8
2.0
3.20
3.36
ratio
0.72
67
790
36
260
1.40
1.11
1.2
1.1
—
—
—
0
0
36
260
1.40
1.11
1.1
1.1
—
—
—
0
0
36
260
1.40
1.11
1.9
3.6
32.56
56.74
mg/l
0.89
27
223
48
364
1.34
1.10
1.6
1.6
14.29
10.72
u/ml
—
8
86
285
2592
1.14
1.09
3.3
3.3
0.01
0.03
estimate
0.39
93
780
114
963
1.21
1.09
2.0
1.9
—
—
—
0
0
42
313
1.36
1.08
1.4
1.8
1.18
1.19
g/l
0.09
37
298
11
60
1.84
1.03
1.1
1.5
9.80
10.71
umol/l
0.20
11
54
72
586
1.25
0.99
1.5
1.6
—
—
—
0
0
32
232
1.39
0.98
1.4
3.4
1.14
3.80
ratio
0.98
16
130
262
2387
1.13
0.97
2.8
3.0
1294.57
873.22
ng/l
0.82
221
2005
12
197
0.60
0.94
1.3
1.6
—
—
—
0
0
28
200
1.41
0.94
1.0
1.1
0.58
2.41
u/ml
1.90
16
102
20
135
1.49
0.89
1.9
3.0
—
2636.09
—
0
11
22
152
1.46
0.88
1.3
1.2
2.62
4.66
u/ml
0.55
16
59
22
152
1.46
0.88
1.2
1.3
177.14
161.50
au/ml
—
7
43
6
31
1.94
0.84
1.2
1.1
—
—
—
0
0
10
57
1.76
0.84
1.0
1.1
—
—
—
0
0
14
89
1.58
0.81
2.7
3.8
—
—
—
0
0
8
47
1.71
0.80
1.0
1.1
—
—
—
0
0
18
258
0.69
0.79
2.1
4.3
1.27
1.26
mmol/l
0.04
18
253
79
668
1.20
0.79
2.9
3.1
0.73
0.76
ug/l
0.18
51
406
16
106
1.52
0.79
1.1
1.2
—
—
—
0
0
6
33
1.82
0.79
1.0
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
—
—
0
0
31
234
1.34
0.78
1.4
1.5
—
—
—
0
0
5
96
0.52
0.78
1.0
1.1
—
—
—
0
0
31
235
1.33
0.76
1.4
1.5
1.18
1.21
ratio
0.06
14
152
31
235
1.33
0.76
1.4
1.5
0.99
1.13
ratio
0.39
14
152
31
235
1.33
0.76
1.4
1.5
1.12
0.97
ratio
0.76
14
152
6
34
1.77
0.76
2.3
1.4
—
—
—
0
0
28
210
1.34
0.74
1.3
1.2
15.85
12.59
u/l
0.41
22
166
10
60
1.67
0.72
1.6
1.5
—
—
—
0
0
7
40
1.76
0.71
1.6
1.6
—
—
—
0
0
9
57
1.58
0.71
1.1
1.1
—
—
—
0
0
28
365
0.76
0.71
1.0
1.2
0.95
0.90
g/l
0.42
28
365
80
686
1.18
0.70
1.9
1.5
—
—
—
0
0
36
283
1.28
0.70
1.4
1.5
—
—
—
0
0
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
32
249
1.29
0.68
3.1
2.8
—
—
—
0
0
11
168
0.65
0.68
1.3
1.7
—
—
—
0
0
57
476
1.21
0.67
1.2
1.4
—
—
—
0
0
301
2823
1.10
0.66
2.8
2.4
53.54
60.74
u/l
1.65
285
2622
11
70
1.58
0.65
1.3
1.4
—
20.56
—
0
9
7
44
1.60
0.65
1.1
1.1
1548.14
1721.23
miu/ml
—
7
44
86
983
0.86
0.64
6.8
6.5
—
—
—
0
0
33
261
1.27
0.63
1.2
1.2
—
—
—
0
0
19
138
1.38
0.63
1.1
1.1
0.25
1.80
—
5
25
298
2801
1.09
0.62
3.9
4.0
4.39
6.55
mg/mmol
0.99
164
1658
60
703
0.84
0.61
2.4
2.5
70.00
68.40
ml/min/173m2
0.13
27
300
236
2198
1.10
0.60
2.5
2.5
313.56
322.39
umol/l
0.70
213
1942
27
210
1.29
0.59
1.9
1.5
2745.90
13394.42
e6/l
2.19
21
149
28
354
0.78
0.59
1.0
1.1
1.64
1.58
g/l
0.54
28
354
0
23
0.00
0.58
0.0
3.0
—
4.65
—
0
23
0
23
0.00
0.58
0.0
3.0
—
10.26
—
0
23
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
25
193
1.30
0.58
4.7
2.6
0.32
0.37
iu/ml
—
10
103
8
55
1.46
0.56
1.6
1.5
1.64
6.13
u/l
—
8
45
17
124
1.38
0.56
1.1
1.1
0.16
0.25
u/ml
—
7
36
86
760
1.14
0.55
2.9
3.1
2.12
1.97
mmol/l
0.14
64
661
15
109
1.38
0.51
1.1
1.2
—
—
—
0
0
337
3209
1.08
0.51
3.0
3.5
76.97
60.01
ng/l
0.13
194
2136
39
325
1.21
0.50
1.1
1.3
193.21
241.91
miu/ml
0.38
20
158
40
335
1.20
0.49
1.8
1.6
258.43
302.73
mu/l
0.67
35
299
109
987
1.12
0.49
2.1
2.0
—
—
—
0
0
10
143
0.70
0.48
1.1
1.5
94.77
54.62
ug/l
—
10
143
31
256
1.22
0.45
1.1
1.1
3.23
4.26
—
7
34
34
405
0.83
0.44
1.8
1.5
—
—
—
0
0
12
86
1.40
0.44
4.3
3.1
58.75
55.37
%
0.30
12
78
37
312
1.19
0.44
1.7
1.9
—
—
—
0
0
19
241
0.78
0.44
1.1
1.2
—
—
—
0
0
5
33
1.52
0.41
5.0
4.8
—
—
—
0
0
5
33
1.52
0.41
1.2
1.1
47.24
42.76
u/ml
—
5
33
0
15
0.00
0.41
0.0
1.1
—
0.61
—
0
10
0
15
0.00
0.41
0.0
2.5
—
0.53
—
0
9
34
287
1.19
0.40
1.6
1.8
—
—
—
0
0
19
150
1.27
0.40
1.2
1.3
—
—
—
0
0
47
409
1.16
0.40
1.4
1.6
1149.77
994.52
mu/l
0.31
37
333
5
35
1.43
0.39
1.0
2.1
43.76
41.33
g/l
—
5
35
5
35
1.43
0.39
1.0
1.0
—
—
—
0
0
42
364
1.16
0.38
1.3
1.5
0.21
0.37
mg/l
1.78
17
153
33
280
1.18
0.38
1.3
1.3
—
—
—
0
0
24
197
1.22
0.38
2.0
2.1
133.83
128.86
g/l
0.47
18
154
78
860
0.90
0.38
2.9
4.2
221.36
19.58
ug/l
0.46
63
691
98
899
1.10
0.37
1.9
1.9
—
—
—
0
0
9
69
1.31
0.37
1.1
1.2
—
—
—
0
0
9
69
1.31
0.37
1.1
1.2
—
—
—
0
0
14
180
0.77
0.37
1.3
1.8
0.74
0.86
nmol/l
—
9
148
188
1776
1.07
0.36
1.7
1.7
74390661.61
34608084.82
pmol/l
0.33
164
1491
96
882
1.10
0.36
3.7
4.4
21.72
22.22
%
0.14
39
404
15
117
1.29
0.35
1.2
2.2
3.36
6.09
umol/l
—
9
82
9
125
0.72
0.35
1.0
1.2
—
0.87
—
0
7
6
44
1.37
0.34
1.5
2.2
—
—
—
0
0
25
297
0.84
0.34
1.1
1.4
73.20
214.05
pmol/l
1.67
25
291
132
1235
1.08
0.33
3.1
1.8
30.13
29.26
s
0.49
126
1197
12
155
0.77
0.33
2.4
1.8
51.42
44.79
nmol/l
0.21
12
149
51
455
1.13
0.32
1.3
1.5
—
—
—
0
0
823
8142
1.08
0.32
4.2
4.2
1.23
1.26
mmol/l
0.92
763
7531
7
53
1.32
0.31
2.1
2.1
—
—
—
0
0
7
54
1.30
0.30
1.1
1.2
—
—
—
0
0
15
185
0.81
0.30
1.1
1.8
—
—
—
0
0
33
377
0.87
0.29
1.6
1.7
3.17
4.67
mg/l
0.43
24
274
9
116
0.77
0.27
2.1
1.6
—
—
—
0
0
56
614
0.91
0.27
2.1
2.3
6.06
6.10
ug/l
0.01
46
548
5
71
0.70
0.26
1.0
1.4
—
—
—
0
0
15
123
1.22
0.25
1.0
1.1
—
—
—
0
0
28
245
1.15
0.25
5.9
2.0
179.46
178.70
%
0.02
28
235
28
246
1.14
0.24
1.6
1.6
—
—
—
0
0
5
40
1.25
0.22
1.4
2.5
18.92
217.85
ug/l
—
5
35
0
11
0.00
0.21
0.0
1.1
—
8.63
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
2.23
—
0
7
107
1015
1.06
0.21
1.4
1.7
1.40
1.41
%
0.03
93
891
20
173
1.16
0.21
3.2
3.9
158.77
1699.86
u/ml
0.57
20
163
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.04
—
0
8
84
791
1.07
0.20
2.9
3.1
5.75
5.80
kpa
0.21
75
774
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
0.01
—
0
9
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.5
1.6
—
—
—
0
0
6
48
1.25
0.20
1.5
1.6
—
—
—
0
0
6
48
1.25
0.20
1.5
1.6
—
—
—
0
0
6
48
1.25
0.20
1.5
1.6
—
—
—
0
0
9
115
0.78
0.20
1.8
1.9
160.33
205.41
pmol/l
—
9
109
50
462
1.09
0.19
3.0
2.9
24.81
24.36
mmol/l
0.55
50
456
6
52
1.15
0.19
1.0
1.3
—
—
—
0
0
7
61
1.15
0.17
1.0
1.3
1.17
1.32
promille
—
7
46
5
70
0.71
0.16
1.6
1.1
—
—
—
0
0
9
78
1.16
0.15
2.4
1.5
—
—
—
0
0
9
79
1.14
0.15
1.2
1.0
—
—
—
0
0
254
2597
0.97
0.14
3.7
4.1
0.00
0.00
estimate
1.34
107
921
23
208
1.11
0.14
2.5
3.9
15.78
34.00
u/ml
2.08
23
201
10
84
1.19
0.14
1.2
1.1
103.40
110.75
pmol/l
—
10
84
115
1110
1.04
0.13
5.3
5.1
2.42
2.27
ug/l
0.10
104
988
13
113
1.15
0.13
1.0
1.4
—
—
—
0
0
15
169
0.89
0.12
2.0
2.4
9.14
80.20
ug/min
—
10
98
13
114
1.14
0.12
1.0
1.4
—
—
—
0
0
13
114
1.14
0.12
1.0
1.4
—
—
—
0
0
86
829
1.04
0.11
2.4
2.1
0.21
0.22
g/l
0.32
77
777
363
3581
1.02
0.11
3.6
3.8
0.31
0.03
estimate
0.50
90
780
19
173
1.10
0.10
1.8
1.3
—
—
—
0
0
26
241
1.08
0.10
1.7
1.6
—
—
—
0
0
70
673
1.04
0.10
7.2
6.6
8.45
8.85
mmol/l
0.24
62
653
42
443
0.95
0.10
1.4
1.5
—
—
—
0
0
51
487
1.05
0.09
3.1
2.8
133.00
128.96
g/l
0.64
45
477
19
174
1.09
0.09
1.6
1.5
—
—
—
0
0
13
116
1.12
0.09
2.2
1.6
—
—
—
0
0
5
48
1.04
0.09
1.2
1.5
—
—
—
0
0
6
55
1.09
0.09
1.3
1.1
—
—
—
0
0
6
56
1.07
0.08
1.2
1.2
—
—
—
0
0
19
175
1.09
0.08
1.1
1.1
11.00
17.00
au/ml
—
5
48
24
224
1.07
0.08
1.4
1.3
—
—
—
0
0
11
123
0.89
0.08
4.1
3.5
1.02
0.78
nmol/l
0.85
11
101
20
215
0.93
0.07
1.4
1.5
538.50
160.45
e6/l
0.32
14
166
9
85
1.06
0.07
1.7
1.5
—
—
—
0
0
9
85
1.06
0.07
1.7
1.5
—
—
—
0
0
9
85
1.06
0.07
1.7
1.5
—
—
—
0
0
8
95
0.84
0.06
1.4
1.1
—
—
—
0
0
30
285
1.05
0.06
1.1
1.3
—
—
—
0
0
64
658
0.97
0.06
2.6
2.6
4.79
4.51
kpa
0.57
59
641
108
1060
1.02
0.05
5.4
4.8
33.40
32.84
%
0.19
73
699
33
344
0.96
0.05
2.8
3.3
25.16
25.42
mmol/l
0.19
27
337
20
212
0.94
0.05
1.4
1.4
10.62
16.42
e6/l
0.25
13
159
11
120
0.92
0.05
1.0
1.1
—
—
—
0
0
13
140
0.93
0.04
2.2
1.7
—
—
—
0
0
28
269
1.04
0.04
4.1
1.8
96.43
95.56
%
0.08
28
259
43
442
0.97
0.03
2.9
3.2
1.92
1.87
mmol/l
0.02
33
329
10
108
0.93
0.03
1.2
1.1
—
—
—
0
0
14
148
0.95
0.02
1.3
1.5
—
—
—
0
0
23
222
1.04
0.02
1.6
1.6
—
—
—
0
0
205
2060
0.99
0.01
3.4
4.1
1.02
1.75
kg/l
0.50
143
1379
84
847
0.99
0.01
2.9
3.1
—
—
—
0
0
15
148
1.01
0.00
1.1
1.1
—
—
—
0
0
109
1091
1.00
0.00
7.6
6.2
104.32
104.17
mmol/l
0.13
109
1091
16
163
0.98
0.00
1.2
1.3
264.10
248.46
u/ml
—
10
94
16
163
0.98
0.00
1.9
1.7
—
—
—
0
0
21
209
1.00
0.00
1.6
1.5
—
—
—
0
0
10
101
0.99
0.00
2.8
2.3
32.00
32.13
pg
—
10
101
11
109
1.01
0.00
1.0
1.4
—
—
—
0
0
11
109
1.01
0.00
1.0
1.4
—
—
—
0
0
35
347
1.01
0.00
1.5
2.1
483.54
4403.39
u/l
2.21
13
144
15
145
1.04
0.00
1.3
1.2
18.08
20.45
u/l
0.13
15
121
18
185
0.97
0.00
1.3
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
8.6
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
7
74
0.95
-0.00
3.3
2.2
—
—
—
0
0
11
110
1.00
-0.00
1.0
1.4
—
—
—
0
0
5
59
0.85
-0.00
1.4
1.3
71.60
75.56
umol/l
—
5
59
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.01
—
0
7
0
5
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.04
—
0
5
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
53
0.94
-0.00
1.2
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint GRAVES_OPHT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| GRAVES_OPHT | 0.959 [0.83, 1.1] | 0.558 |
| Birth year | 0.994 [0.99, 1.0] | 0.163 |
During the follow-up period (1.1.1998 — 31.12.2019), 269 out of 3299 females with GRAVES_OPHT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| GRAVES_OPHT | 0.932 [0.75, 1.16] | 0.532 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 762 males with GRAVES_OPHT died.
Mortality risk
Mortality risk for people of age
years, who have GRAVES_OPHT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.083% | 0.178% |
| 5 | 0.592% | 1.02% |
| 10 | 1.423% | 2.475% |
| 15 | 2.785% | 4.756% |
| 20 | 4.852% | 8.199% |
Relationships between endpoints
↥Index endpoint: GRAVES_OPHT – Graves ophthalmopathy
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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