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Other and unspecified disorders of orbit

DOID Endpoint Browser PheWeb

H7_ORBITNAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H05.8, H05.9
  • Hospital discharge: ICD-9 — 376[8-9]
  • Cause of death: ICD-10 — H05.8, H05.9
  • Cause of death: ICD-9 — 376[8-9]

2 out of 7 registries used, show all original rules.

202

4. Check minimum number of events

None

202

5. Include endpoints

None

202

6. Filter based on genotype QC (FinnGen only)

184

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1041 548 489
Only index persons 942 504 438
Unadjusted period prevalence (%)
Whole population 0.01 0.02 0.01
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 56.46 57.28 55.63
Only index persons 55.79 56.02 55.53

-FinnGen-

Key figures

All Female Male
Number of individuals 184 103 81
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 61.87 60.45 63.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
191
Matched controls
1910
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H05.8
ICD-10 Finland
Other disorders of orbit
+∞
113.1
97
*
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
110.4
95
*
CAA30
NOMESCO Finland
Biopsy of orbit
+∞
30.0
28
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
326.7
28.6
28
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.3
18.3
62
193
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.6
17.2
115
560
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
16.9
16
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
49.4
15.4
18
*
H05.0
ICD-10 Finland
Acute inflammation of orbit
+∞
14.8
14
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.9
14.1
35
84
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.9
13.9
27
52
H04.10
ICD-10 Finland
Dry eye syndrome
5.7
13.3
27
54
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
138.7
12.6
13
*
H02.4
ICD-10 Finland
Ptosis of eyelid
40.4
12.4
15
*
H02.3
ICD-10 Finland
Blepharochalasis
24.8
11.8
16
7
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
+∞
11.6
11
*
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
127.4
11.6
12
*
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
+∞
10.5
10
*
XCK10
NOMESCO Finland
Photography of fundus of eye
4.0
10.3
32
91
WX140
NOMESCO Finland
Parabulbar anesthesy
5.0
9.8
22
48
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
105.0
9.5
10
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
9.8
9.3
18
20
H01.0
ICD-10 Finland
Blepharitis
5.3
9.0
19
39
Z3229
NOMESCO Finland
Other healthcare associate professional
4.0
8.8
27
76
CAW99
NOMESCO Finland
Other operation on orbit
+∞
8.4
8
*
WX002
NOMESCO Finland
Sedation and analgesia
2.9
8.3
48
201
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
8.0
85
477
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.4
7.8
78
424
F29
ICPC
Eye symptom/complaint other
3.2
7.6
33
117
H57.1
ICD-10 Finland
Ocular pain
6.3
7.4
19
33
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
7.3
7
*
CAE10
NOMESCO Finland
Revision and secondary implant in orbit
+∞
7.3
7
*
H05.1
ICD-10 Finland
Chronic inflammatory disorders of orbit
+∞
7.3
7
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
7.3
7
*
XCK00
NOMESCO Finland
Perimetry
4.4
7.3
19
47
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.3
7.2
29
98
S01ED51
ATC
timolol, combinations; ophthalmic
3.7
7.1
24
72
ZXA00
NOMESCO Finland
Right side
2.4
7.0
64
333
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.6
6.9
17
40
F01
ICPC
Eye pain
7.7
6.9
15
21
WF002
NOMESCO Finland
Radical radiotherapy
4.3
6.8
18
45
H53.2
ICD-10 Finland
Diplopia
6.3
6.8
17
29
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.3
6.6
26
86
H02AB06
ATC
prednisolone; systemic
2.2
6.6
104
673
J01FF01
ATC
clindamycin; systemic
2.3
6.5
64
342
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
18.8
6.3
9
5
CBA10
NOMESCO Finland
Biopsy of eyelid
18.8
6.3
9
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
6.3
107
710
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
6.3
6
*
CCA10
NOMESCO Finland
Biopsy of lacrimal gland
+∞
6.3
6
*
CA1AD
NOMESCO Finland
Orbita CT
+∞
6.3
6
*
CAE00
NOMESCO Finland
Removal of implant from orbit
+∞
6.3
6
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
6.2
80
475
ZXE00
NOMESCO Finland
One hour or less
2.1
6.0
85
522

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
43
8.09
20.57
1.9
1.8
2.04
2.72
iu/l
0.75
13
16
27
48
6.39
15.08
1.3
1.1
—
—
—
0
0
27
60
5.08
11.85
1.6
1.4
—
—
—
0
0
127
785
2.84
10.61
9.3
6.3
0.67
0.65
%
0.17
122
736
96
519
2.71
10.40
6.0
4.2
7.40
7.40
ph
0.04
72
365
58
243
2.99
10.18
2.1
1.9
—
—
—
0
0
134
865
2.84
10.05
9.6
6.2
0.61
0.57
e9/l
1.02
114
748
126
789
2.75
10.03
9.4
6.3
2.91
2.94
%
0.04
120
745
128
809
2.77
9.98
9.3
6.4
27.13
27.07
%
0.02
122
775
126
792
2.74
9.90
9.4
6.4
9.03
8.75
%
0.47
121
748
134
870
2.81
9.85
9.6
6.2
0.04
0.04
e9/l
0.33
114
752
98
550
2.61
9.64
8.3
5.7
—
—
—
0
0
17
17
10.85
9.23
2.4
1.4
—
—
—
0
0
134
887
2.71
9.19
9.7
6.3
1.92
1.92
e9/l
0.02
118
793
125
802
2.62
9.11
9.2
6.3
57.46
58.27
%
0.31
120
769
134
902
2.63
8.62
10.1
6.3
0.20
0.20
e9/l
0.07
118
793
141
973
2.72
8.61
15.8
10.0
4.48
4.12
e9/l
0.77
125
855
128
844
2.57
8.59
7.5
7.1
1.22
1.21
mmol/l
0.33
114
727
53
231
2.79
8.50
1.5
1.4
288.00
472.59
titre
0.77
15
54
63
311
2.53
7.81
1.9
2.0
—
—
—
0
0
17
24
7.66
7.67
1.4
1.2
—
—
—
0
0
97
590
2.31
7.44
4.6
3.2
2.35
2.35
mmol/l
0.06
90
537
56
274
2.48
6.98
1.8
1.7
—
—
—
0
0
35
140
2.84
6.48
2.8
3.2
68.03
67.35
g/l
0.23
35
129
32
124
2.90
6.27
1.7
1.6
—
—
—
0
0
41
184
2.56
6.06
2.0
1.7
—
—
—
0
0
35
152
2.59
5.51
1.7
1.4
—
—
—
0
0
84
530
2.04
5.41
3.8
2.8
0.37
0.49
e6/l
0.26
59
379
29
116
2.77
5.35
2.4
2.9
—
—
—
0
0
12
18
7.03
5.34
1.2
1.2
—
—
—
0
0
83
528
2.01
5.18
9.0
6.3
—
—
—
0
0
185
1666
4.51
4.76
25.7
15.1
21.95
24.07
mg/l
0.47
165
1365
36
171
2.36
4.67
1.6
1.9
—
—
—
0
0
84
552
1.93
4.65
3.2
2.4
58.28
64.75
u/l
0.33
75
510
91
619
1.90
4.51
4.0
3.1
19.23
41.18
e6/l
1.11
68
465
110
798
1.89
4.44
15.2
11.6
0.00
0.00
e9/l
0.48
88
653
39
198
2.22
4.32
1.7
1.7
—
—
—
0
0
14
41
3.61
4.27
1.2
1.6
—
—
—
0
0
74
481
1.88
4.14
5.7
4.0
—
—
—
0
0
158
1318
2.15
3.96
12.5
7.9
78.48
79.74
u/l
0.13
153
1246
14
44
3.35
3.86
1.4
1.3
—
2.26
—
0
8
108
811
1.76
3.61
17.7
13.4
1.25
1.22
inr
0.22
93
664
7
9
8.02
3.59
2.1
3.3
428.71
1199.67
u/ml
—
7
9
48
288
1.89
3.35
3.3
2.9
1.40
2.03
e6/l
0.38
21
130
13
43
3.17
3.32
1.1
1.1
—
—
—
0
0
31
161
2.10
3.23
3.7
3.3
68.46
74.92
e9/l
0.44
21
119
93
688
1.69
3.13
4.7
3.9
136.80
71.99
e6/l
0.53
66
478
45
274
1.84
2.98
1.8
1.7
1131.73
1202.57
nmol/l
0.21
35
202
91
676
1.66
2.98
2.4
2.0
—
—
—
0
0
36
204
1.94
2.96
1.6
1.4
—
—
—
0
0
96
724
1.66
2.95
2.2
2.0
93.12
97.01
pmol/l
0.26
45
366
9
22
4.24
2.92
2.2
3.1
—
—
—
0
0
6
9
6.84
2.89
1.2
1.4
—
—
—
0
0
51
327
1.76
2.84
4.3
3.5
37.35
408.00
ng/l
2.15
46
250
57
378
1.72
2.83
1.7
1.4
2.69
2.71
g/l
0.02
46
227
11
34
3.37
2.77
1.6
1.4
—
—
—
0
0
6
10
6.15
2.72
1.5
5.0
70.83
229.10
nmol/l
—
6
10
19
87
2.31
2.67
1.6
1.6
0.19
0.33
mg/l
1.21
12
38
34
197
1.88
2.62
3.6
7.2
7.41
7.42
ph
0.08
20
110
63
439
1.65
2.57
2.4
2.2
2.99
2.93
mg/l
0.06
53
385
31
176
1.91
2.53
4.8
3.9
2.20
2.17
mmol/l
0.02
26
152
26
141
1.98
2.42
6.0
7.1
10.29
9.80
mmol/l
0.11
26
132
41
259
1.74
2.39
2.9
2.6
20.50
22.85
%
0.49
41
243
5
8
6.38
2.38
1.0
1.0
—
—
—
0
0
5
8
6.38
2.38
1.0
1.0
—
—
—
0
0
5
8
6.38
2.38
1.0
1.0
—
—
—
0
0
117
960
1.56
2.32
4.9
3.9
0.00
0.02
estimate
0.50
24
188
101
805
1.54
2.26
3.3
3.1
222.08
129.92
ug/l
0.61
95
745
115
944
1.55
2.25
4.9
3.9
0.00
0.00
estimate
-0.00
26
207
59
420
1.59
2.17
3.6
2.5
5.95
4.99
e6/l
0.23
54
390
31
186
1.80
2.14
1.8
1.3
—
—
—
0
0
27
155
1.86
2.14
1.5
1.5
—
—
—
0
0
50
345
1.61
2.08
4.5
2.7
560.64
536.18
mosm/kgh2o
0.34
42
301
5
10
5.10
2.08
1.4
1.1
—
—
—
0
0
114
944
1.52
2.07
4.8
3.8
0.00
0.00
estimate
-0.00
25
199
30
181
1.78
2.04
4.9
3.9
7.38
7.38
ph
0.05
19
100
34
213
1.73
2.03
1.3
1.2
—
—
—
0
0
9
32
2.90
2.03
1.6
1.5
—
—
—
0
0
49
340
1.59
1.99
1.4
1.3
30.92
39.03
iu/ml
0.24
13
97
147
1292
1.60
1.98
5.8
4.2
14.64
14.85
pmol/l
0.50
137
1174
18
92
2.06
1.97
1.0
1.2
403.40
130.11
u/ml
—
5
37
70
528
1.51
1.96
4.3
2.9
—
—
—
0
0
8
27
3.05
1.96
2.1
2.4
30.50
32.41
pg
—
8
27
9
33
2.81
1.96
1.7
2.9
—
—
—
0
0
59
430
1.54
1.93
4.0
3.7
—
0.40
—
0
5
18
93
2.03
1.92
1.8
4.0
—
—
—
0
0
170
1556
1.84
1.90
7.0
5.1
1.96
1.93
mu/l
0.12
158
1422
80
628
1.47
1.82
3.1
3.2
7.78
7.85
mmol/l
0.04
68
540
7
23
3.12
1.81
2.4
2.3
—
—
—
0
0
34
221
1.66
1.78
1.2
1.3
—
—
—
0
0
6
18
3.41
1.76
1.0
1.2
—
—
—
0
0
13
62
2.18
1.70
1.5
1.5
—
—
—
0
0
13
62
2.18
1.70
1.5
1.5
—
—
—
0
0
13
62
2.18
1.70
1.5
1.5
—
—
—
0
0
6
19
3.23
1.67
1.2
1.1
—
—
—
0
0
5
14
3.64
1.62
1.2
1.5
12.60
48.19
ng/l
—
5
14
5
14
3.64
1.62
1.0
1.2
—
—
—
0
0
7
26
2.75
1.59
3.0
2.8
3.66
4.35
e9/l
—
7
26
91
746
1.42
1.59
4.2
3.5
6.42
6.22
ph
0.92
45
420
23
140
1.73
1.53
6.1
3.2
—
—
—
0
0
25
157
1.68
1.50
6.9
8.4
—
—
—
0
0
9
40
2.31
1.42
1.4
1.2
—
—
—
0
0
11
53
2.14
1.41
1.9
2.7
0.67
1.43
index
—
6
30
7
29
2.47
1.40
1.4
3.0
5.94
8.84
pmol/l
—
7
29
5
17
2.99
1.36
2.6
1.7
12.18
11.17
%
—
5
17
12
61
2.03
1.36
1.5
1.5
—
—
—
0
0
34
237
1.53
1.35
5.8
6.2
102.53
103.70
mmol/l
0.71
34
237
170
1588
1.64
1.33
7.5
6.6
39.83
39.40
mmol/mol
0.24
163
1489
25
163
1.61
1.31
4.6
2.1
44.68
28.52
u/l
0.92
19
132
5
18
2.82
1.29
1.0
1.2
—
—
—
0
0
5
18
2.82
1.29
1.0
1.2
—
—
—
0
0
68
548
1.37
1.26
5.2
3.9
0.00
0.01
estimate
0.50
25
186
172
1618
1.63
1.22
6.2
5.3
5.86
5.96
mmol/l
0.62
158
1478
7
30
2.38
1.13
4.3
2.8
3.77
1.97
mmol/l
—
7
18
7
30
2.38
1.13
1.7
1.1
—
—
—
0
0
24
162
1.55
1.11
4.6
6.3
0.00
0.09
%
—
10
47
23
155
1.55
1.07
4.6
5.7
0.22
0.42
%
—
9
51
81
687
1.31
1.03
4.5
3.9
55.21
37.04
ng/l
0.26
57
506
10
53
1.94
1.03
1.5
1.5
—
—
—
0
0
11
61
1.85
1.00
1.5
1.5
—
—
—
0
0
7
36
1.98
0.98
4.9
5.3
—
—
—
0
0
7
36
1.98
0.98
1.7
1.0
125.00
3.50
e6/l
—
7
28
18
117
1.59
0.98
5.7
8.8
92.19
94.21
%
0.67
18
117
22
151
1.52
0.95
4.7
6.1
0.13
0.20
%
—
8
45
23
160
1.50
0.94
4.6
5.9
0.67
0.84
%
—
9
54
70
590
1.29
0.92
3.2
3.4
22.53
41.38
mg/l
1.30
50
384
60
498
1.30
0.88
1.8
1.7
21.03
20.79
nmol/l
0.05
52
416
11
64
1.76
0.88
1.5
1.8
—
—
—
0
0
16
104
1.59
0.88
1.1
1.2
—
—
—
0
0
56
463
1.30
0.84
3.2
2.8
346.18
346.85
umol/l
0.02
50
405
71
606
1.27
0.84
3.7
4.0
2.81
7.00
mg/mmol
2.43
50
375
8
46
1.77
0.83
1.4
1.9
—
—
—
0
0
6
32
1.90
0.82
1.8
6.8
1.32
1.17
mmol/l
—
6
27
27
201
1.40
0.80
2.6
2.3
278.50
99.57
ug/g
0.47
20
164
8
48
1.70
0.80
1.4
1.6
—
—
—
0
0
6
33
1.84
0.79
1.2
1.1
—
—
—
0
0
58
486
1.28
0.79
3.3
3.1
—
0.00
—
0
13
11
67
1.68
0.77
1.5
1.3
—
—
—
0
0
39
311
1.32
0.76
1.3
1.3
1.17
13.50
u/ml
2.82
12
133
9
55
1.67
0.74
14.9
12.9
—
—
—
0
0
7
38
1.87
0.74
1.7
1.1
792.57
251.27
e6/l
—
7
30
182
1767
1.64
0.73
33.0
19.9
77.74
77.29
umol/l
0.08
182
1747
9
57
1.61
0.72
4.2
2.7
—
—
—
0
0
7
40
1.78
0.72
3.3
2.7
56.14
58.55
%
—
7
40
91
811
1.23
0.72
3.5
2.6
—
—
estimate
—
0
0
5
26
1.95
0.71
3.4
1.6
18.20
16.91
ug/l
—
5
26
12
77
1.60
0.70
1.2
1.1
—
—
—
0
0
57
484
1.25
0.69
1.6
1.5
—
—
—
0
0
18
128
1.45
0.68
4.9
3.3
—
—
—
0
0
7
44
1.61
0.66
1.0
1.3
—
—
—
0
0
8
50
1.63
0.62
1.3
1.1
—
58.00
—
0
5
8
51
1.59
0.61
1.9
1.4
—
—
—
0
0
80
713
1.21
0.61
5.5
3.7
0.00
0.03
estimate
0.78
22
171
181
1760
1.54
0.61
17.9
11.9
26.42
26.08
u/l
0.12
176
1707
13
89
1.49
0.59
1.2
1.2
—
—
—
0
0
8
53
1.53
0.59
1.3
1.1
—
—
—
0
0
49
417
1.24
0.58
8.2
5.6
—
—
—
0
0
12
82
1.49
0.56
5.5
4.0
36.98
36.91
°c
0.37
12
82
6
38
1.60
0.55
1.0
2.4
91.42
88.78
%
—
6
38
185
1814
1.63
0.53
39.9
23.8
134.17
135.01
g/l
0.33
185
1794
185
1812
1.67
0.53
40.0
24.0
40.27
40.32
%
0.05
185
1791
185
1812
1.67
0.53
39.5
23.6
30.21
30.32
pg
0.37
185
1792
185
1811
1.69
0.53
39.5
23.6
91.09
91.13
fl
0.03
185
1791
9
64
1.43
0.52
1.1
1.2
—
—
—
0
0
11
156
0.69
0.52
1.5
1.4
—
—
—
0
0
63
559
1.19
0.49
3.1
2.3
—
—
—
0
0
49
429
1.19
0.44
5.3
3.7
1.02
1.02
kg/l
0.08
34
274
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
20
160
1.28
0.40
1.3
1.5
—
—
—
0
0
61
672
0.86
0.38
3.7
3.4
—
—
—
0
0
6
47
1.29
0.32
1.2
1.1
—
—
—
0
0
7
53
1.33
0.31
1.1
2.6
8.34
7.96
kpa
—
7
53
57
522
1.13
0.29
5.0
3.3
0.00
0.01
estimate
0.50
20
169
28
318
0.86
0.26
3.5
2.8
0.56
0.75
ug/l
1.06
21
197
175
1722
1.19
0.22
20.0
13.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
102.50
—
0
10
13
108
1.22
0.20
4.9
2.4
0.67
0.65
%
0.09
13
108
7
60
1.17
0.18
1.4
2.6
22.49
25.28
mmol/l
—
7
60
13
110
1.20
0.17
5.0
2.5
1.28
1.26
%
0.03
13
110
43
401
1.09
0.16
2.3
1.6
1.91
1.23
mg/l
0.25
33
320
7
85
0.82
0.15
2.1
4.2
—
—
—
0
0
7
87
0.80
0.15
1.4
2.0
—
—
—
0
0
164
1663
0.90
0.14
5.9
5.3
4.53
4.59
mmol/l
0.30
153
1547
171
1688
1.12
0.14
6.6
6.0
2.57
2.67
mmol/l
0.74
160
1563
44
415
1.08
0.13
1.5
1.3
0.82
1.65
u/ml
0.80
12
117
79
763
1.06
0.12
2.1
1.9
1.39
1.36
mmol/l
0.09
65
639
5
61
0.81
0.08
2.0
1.1
1.49
1.56
g/l
—
5
61
7
65
1.08
0.08
3.0
2.6
13.00
3357.56
u/ml
—
7
54
158
1596
0.94
0.07
4.9
4.4
1.41
1.27
mmol/l
1.35
147
1471
7
82
0.85
0.07
2.3
2.3
—
—
—
0
0
37
356
1.05
0.06
2.0
1.8
451.34
39262166.88
pmol/l
0.50
29
298
165
1660
0.96
0.03
5.8
5.2
1.40
1.47
mmol/l
1.24
153
1535
19
184
1.04
0.00
1.4
1.7
—
—
—
0
0
57
566
1.01
0.00
4.8
5.1
2.20
2.42
ug/l
0.12
52
509
14
142
0.98
0.00
2.1
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
19.05
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
62
0.97
-0.00
1.8
1.1
0.74
0.87
g/l
—
6
62
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_ORBITNAS and mortality.

Females

Parameter HR [95% CI] p-value
H7_ORBITNAS 1.807 [1.27, 2.57] 0.001
Birth year 0.993 [0.98, 1.0] 0.157

During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 411 females with H7_ORBITNAS died.

Males

Parameter HR [95% CI] p-value
H7_ORBITNAS 1.939 [1.29, 2.91] 0.001
Birth year 0.989 [0.98, 1.0] 0.021

During the follow-up period (1.1.1998 — 31.12.2019), 70 out of 371 males with H7_ORBITNAS died.

Mortality risk

Mortality risk for people of age

years, who have H7_ORBITNAS.

N-year risk Females Males
1 0.144% 0.383%
5 0.889% 2.239%
10 2.464% 5.928%
15 4.762% 11.4%
20 8.392% 19.205%

Relationships between endpoints

↥

Index endpoint: H7_ORBITNAS – Other and unspecified disorders of orbit

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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