erythema multiforme: Erythema multiforme (EM) refers to a group ofhypersensitivity disorders characterized by symmetric red, patchy lesions, primarily on the arms and legs. The cause is unknown, but EM frequently occurs in association with herpes simplex virus , suggesting an immunologic process initiated by the virus. In half of the cases, the triggering agents appear to be medications, including anticonvulsants, sulfonamides, nonsteroidal anti-inflammatory drugs, and other antibiotics. In addition, some cases appear to be associated with infectious organisms such as Mycoplasma pneumoniae and many viral agents. Erythema multiforme is the mildest of three skin disorders that are often discussed in relation to each other. It is generally the mildest of the three. More severe is Stevens-Johnson syndrome . The most severe of the three is toxic epidermal necrolysis (TEN).
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
981 |
4. Check minimum number of eventsNone |
981 |
5. Include endpointsNone |
981 |
6. Filter based on genotype QC (FinnGen only) |
887 |
Control definitions (FinnGen only)
- Control exclude
- L12_URTICARIAERYTHEMA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L50-L54
- Name in latin
- Erythema multiforme
Similar endpoints
↥List of similar endpoints to
Erythema multiforme
based on the number of shared cases.
Similar with more cases:
- Urticaria and erythema
- Diseases of the skin and subcutaneous tissue
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7231 | 3832 | 3367 |
| Only index persons | 6249 | 3374 | 2875 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.09 |
| Only index persons | 0.12 | 0.12 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 43.65 | 47.82 | 38.77 |
| Only index persons | 42.72 | 46.91 | 37.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 887 | 548 | 339 |
| Unadjusted period prevalence (%) | 0.18 | 0.19 | 0.16 |
| Median age at first event (years) | 50.69 | 47.66 | 55.60 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 912
- Matched controls
- 9120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L51.9
ICD-10 Finland
Erythema multiforme, unspecified
5410.7
307.7
356
*
L51.0
ICD-10 Finland
Nonbullous erythema multiforme
+∞
205.2
189
*
L51.8
ICD-10 Finland
Other erythema multiforme
+∞
151.4
141
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.0
127.4
229
415
L51.1
ICD-10 Finland
Bullous erythema multiforme
+∞
124.9
117
*
H02AB06
ATC
prednisolone; systemic
4.0
86.8
623
3178
6951A
ICD-9 Finland
Erythematous conditions, Erythema multiforme[ERYTHEMA MULTIFORME]
+∞
72.9
69
*
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
17.1
69.0
58
36
L51.19
ICD-10 Finland
Other bullous erythema multiforme
+∞
65.4
62
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.3
58.5
308
1225
L50.9
ICD-10 Finland
Urticaria, unspecified
9.8
56.3
67
73
L51.10
ICD-10 Finland
Stevens-Johnson syndrome
+∞
52.6
50
*
D07AC01
ATC
betamethasone; topical
2.8
48.7
435
2268
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.8
40.4
141
424
D07AB08
ATC
desonide; topical
3.3
36.5
158
544
L51
ICD-10 Finland
Erythema multiforme
77.2
33.1
37
5
P01BA02
ATC
hydroxychloroquine; oral
3.5
32.2
122
385
L04AX01
ATC
azathioprine; systemic
4.9
30.8
71
155
J05AB01
ATC
aciclovir; systemic
2.5
30.8
266
1308
R06AE07
ATC
cetirizine; oral
2.2
29.0
463
2929
69510
ICD-8 Finland
Erythematous condition, Eetodermosis multiformis (syndroma Stevens-Johnson)
+∞
28.3
27
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.2
28.1
79
202
J05AB11
ATC
valaciclovir; oral
2.6
26.3
187
833
H02AB07
ATC
prednisone; oral
2.6
25.7
169
725
TQW80
NOMESCO Finland
Local dermatologic skincare
6.0
25.6
46
80
E0000UV, ,
ATC
2.0
24.1
427
2748
L50.0
ICD-10 Finland
Allergic urticaria
7.9
23.9
33
43
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
23.9
474
3175
R50.9
ICD-10 Finland
Fever, unspecified
2.4
23.3
184
857
E000001, ,
ATC
2.3
22.6
216
1093
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.7
22.2
134
548
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
22.2
315
1859
XQ802
NOMESCO Finland
Epicutan test
4.1
21.4
60
153
L04AX03
ATC
methotrexate; systemic
2.7
20.6
119
475
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
20.5
343
2132
L50.8
ICD-10 Finland
Other urticaria
24.0
20.0
28
12
T78.4
ICD-10 Finland
Allergy, unspecified
3.9
19.2
58
156
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.4
18.8
151
705
D07AC13
ATC
mometasone; topical
2.0
18.4
285
1714
6951B
ICD-9 Finland
Erythematous conditions, Erythema multiforme[SYNDROMA STEVENS-JOHNSON]
+∞
17.8
17
*
L51.2
ICD-10 Finland
Toxic epidermal necrolysis [Lyell]
+∞
17.8
17
*
D07AA02
ATC
hydrocortisone; topical
2.2
16.4
157
786
L01BA01
ATC
methotrexate; systemic
3.9
16.3
48
127
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
16.0
63
202
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.8
15.7
81
304
XQ848
NOMESCO Finland
Dermatological photography
4.1
15.4
42
105
L04AA06
ATC
mycophenolic acid; systemic
5.1
15.3
32
64
J01FF01
ATC
clindamycin; systemic
1.9
15.0
264
1638
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.8
14.6
33
71
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
14.5
142
716
R06AX27
ATC
desloratadine; oral
1.8
14.4
278
1772
K12.10
ICD-10 Finland
Stomatitis NOS
13.8
13.8
23
17
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
13.4
222
1344
J01MA12
ATC
levofloxacin; systemic
1.9
13.1
178
1009
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
13.1
119
582
L12.0
ICD-10 Finland
Bullous pemphigoid
13.2
13.0
22
17
J04BA02
ATC
dapsone; oral
19.4
12.9
19
10
D07AD01
ATC
clobetasol; topical
2.0
12.7
163
907
XQ800
NOMESCO Finland
Prick test
2.5
12.0
75
310
H02AB04
ATC
methylprednisolone; systemic
2.0
11.9
140
753
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
11.9
11.9
21
18
L04AD01
ATC
ciclosporin; systemic
4.8
11.7
26
55
A07AA02
ATC
nystatin; oral
2.7
11.7
65
254
H02AB09
ATC
hydrocortisone; systemic
4.0
11.6
33
85
M05BA04
ATC
alendronic acid; oral
2.3
11.5
88
399
J01MA02
ATC
ciprofloxacin; systemic
1.6
11.3
342
2434
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.2
11.1
44
142
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.1
11.0
30
75
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.6
11.0
26
58
D69.0
ICD-10 Finland
Allergic purpura
12.1
10.9
19
16
N05CF01
ATC
zopiclone; oral
1.7
10.9
292
2014
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
10.8
96
465
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.4
10.6
39
120
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.6
10.5
25
56
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.5
10.5
70
299
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
10.3
210
1343
D05BB02
ATC
acitretin; oral
4.2
10.2
27
66
J01DB01
ATC
cefalexin; oral
1.8
10.2
742
6485
A02BC02
ATC
pantoprazole; systemic
1.6
10.2
603
4999
L13.9
ICD-10 Finland
Bullous disorder, unspecified
11.5
10.1
18
16
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.5
9.9
34
100
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
7.7
9.9
22
29
D01BA02
ATC
terbinafine; oral
1.7
9.9
226
1487
J01AA02
ATC
doxycycline; systemic
1.7
9.9
678
5802
L04AB04
ATC
adalimumab; parenteral
3.9
9.8
29
77
J01FA06
ATC
roxithromycin; oral
1.6
9.8
352
2591
L93.1
ICD-10 Finland
Subacute cutaneous lupus erythematosus
55.6
9.7
11
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
9.6
93
465
N05BB01
ATC
hydroxyzine; systemic
2.4
9.6
65
280
SPAT1263
SPAT
Sampling
1.6
9.4
365
2728
R06AE09
ATC
levocetirizine; oral
1.9
9.4
133
760
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
21.9
9.4
13
6
B00.10
ICD-10 Finland
Herpes simplex facialis
7.0
9.4
22
32
J01DA01
ATC
[U] cefalexin
1.6
9.3
542
4430
L04AA13
ATC
[U] leflunomide
3.6
9.3
30
85
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.3
9.1
34
106
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
9.0
54
220
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
8.9
97
507
L50.3
ICD-10 Finland
Dermatographic urticaria
10.8
8.8
16
15
D02AX
ATC
Other emollients and protectives
3.2
8.7
34
109
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
8.6
104
563
L40.9
ICD-10 Finland
Psoriasis, unspecified
4.8
8.6
19
40
A46
ICD-10 Finland
Erysipelas
1.8
8.6
127
736
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.2
8.6
33
105
L12.9
ICD-10 Finland
Pemphigoid, unspecified
16.5
8.6
13
8
L27.1
ICD-10 Finland
Localized skin eruption due to drugs and medicaments
10.2
8.5
16
16
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
8.5
112
624
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
8.4
229
1569
M14.8*L51.9
ICD-10 Finland
Arthropathy in erythema: multiforme
+∞
8.3
8
*
S18
ICPC
Laceration/cut
1.5
8.3
411
3213
J01MA14
ATC
moxifloxacin; systemic
2.0
8.2
86
443
A03
ICPC
Fever
1.7
8.2
163
1029
R03AC02
ATC
salbutamol; inhalant
1.5
8.2
494
4022
SBA00
NOMESCO Finland
Microbiological examinations
3.4
8.1
29
88
B02.9
ICD-10 Finland
Zoster without complication
2.2
8.1
66
308
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
8.0
101
555
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.0
7.9
35
121
N02AX02
ATC
tramadol; systemic, rectal
1.5
7.8
370
2856
C03CA01
ATC
furosemide; systemic
1.6
7.8
241
1697
B00.11
ICD-10 Finland
Herpes simplex labialis
3.7
7.8
24
66
S29
ICPC
Skin symptom/complaint other
1.6
7.8
180
1183
A01AB09
ATC
miconazole; local oral
2.0
7.8
81
417
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.9
7.7
36
129
L04AA01
ATC
[U] ciclosporin
6.2
7.6
19
31
N03AX16
ATC
[U] pregabalin
1.6
7.6
199
1349
L52
ICD-10 Finland
Erythema nodosum
10.1
7.5
14
14
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
7.5
454
3670
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
7.3
221
1545
K12.18
ICD-10 Finland
Other forms of stomatitis
8.5
7.3
15
18
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
7.3
150
955
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.6
7.2
23
65
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.6
7.1
39
152
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
5.7
7.1
19
34
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
7.1
91
504
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.8
7.0
34
124
N03AX14
ATC
levetiracetam; systemic
3.0
7.0
30
102
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.1
7.0
65
320
N02AA05
ATC
oxycodone; systemic
1.7
7.0
155
1005
D06AX01
ATC
fusidic acid; topical
1.9
7.0
86
469
A02BC03
ATC
lansoprazole; oral
1.5
7.0
241
1734
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
7.0
121
735
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.2
6.9
27
87
J02AC01
ATC
fluconazole; systemic
1.5
6.9
329
2529
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
6.9
369
2901
D07BC01
ATC
betamethasone and antiseptics; topical
1.8
6.9
100
576
SPAT1153
SPAT
Removal of sutures
1.5
6.8
255
1865
D07XC01
ATC
betamethasone; topical
1.8
6.8
99
570
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
6.2
6.8
17
28
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
40.4
6.8
8
*
L88
ICPC
Rheumatoid/seropositive arthritis
2.5
6.7
40
163
L29.9
ICD-10 Finland
Pruritus, unspecified
2.8
6.7
33
122
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
6.7
110
658
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.7
315
2414
AA1AD
NOMESCO Finland
CT of head and brain
1.5
6.7
236
1706
N06AX11
ATC
mirtazapine; oral
1.5
6.6
297
2252
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.6
133
842
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
8.8
6.6
13
15
N03AX12
ATC
[U] gabapentin; oral
1.7
6.5
139
891
ZX120
NOMESCO Finland
Intravenous
1.9
6.5
84
465
D06
ICPC
Abdominal pain localized other
1.9
6.5
79
430
M25.5
ICD-10 Finland
Pain in joint
1.5
6.4
290
2199
A07EA06
ATC
budesonide; oral, local oral
2.6
6.4
37
148
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
6.4
113
690
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
6.3
112
683
E000002, ,
ATC
1.8
6.3
93
538
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.3
242
1778
5280A
ICD-9 Finland
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue, Stomatitis
+∞
6.3
6
*
134
Kela drug reimbursment
General erythroderma
+∞
6.3
6
*
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.2
231
1683
J01EA01
ATC
trimethoprim; systemic
1.5
6.2
221
1597
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
6.2
66
343
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.9
6.1
28
99
B08.4
ICD-10 Finland
Enteroviral vesicular stomatitis with exanthem
7.7
6.1
13
17
L40.5
ICD-10 Finland
Arthropathic psoriasis
3.8
6.1
18
48
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
6.1
91
529
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
3.9
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
61
51
12.75
61.39
1.7
1.5
32.47
21.20
u/ml
—
15
5
107
250
4.72
43.08
2.8
1.5
0.21
0.23
g/l
1.72
101
241
108
259
4.60
42.08
2.8
1.4
1.14
1.19
g/l
0.88
102
246
120
317
4.21
41.24
3.1
1.8
21.21
8.32
iu/ml
0.78
31
79
56
91
6.49
33.39
1.4
1.2
—
—
—
0
0
75
191
4.19
26.83
1.6
1.2
—
—
—
0
0
71
181
4.17
25.35
1.8
1.2
1.68
6.87
u/ml
—
6
13
622
4543
2.16
25.34
15.6
9.6
4.16
4.12
e9/l
0.18
563
3963
79
228
3.70
23.71
1.9
1.2
6.49
9.64
u/ml
0.24
19
39
79
228
3.70
23.71
1.9
1.2
2.65
2.49
u/ml
0.06
11
25
96
316
3.28
23.52
1.4
1.2
0.18
1.51
u/ml
—
5
20
81
243
3.56
22.94
1.9
1.2
100.54
2.80
u/ml
—
10
11
133
558
2.62
20.91
2.1
1.7
—
—
—
0
0
239
1323
2.09
19.62
2.6
1.9
—
—
—
0
0
60
163
3.87
19.61
8.6
6.4
962.88
361.00
iu/ml
—
8
17
486
3444
1.88
19.14
7.2
5.1
35.32
35.91
g/l
1.56
459
3229
28
46
6.25
16.46
2.1
2.5
—
—
—
0
0
29
50
5.96
16.26
2.1
2.4
471.10
523.27
e6/l
0.17
21
40
720
5948
2.00
16.11
12.8
8.2
77.24
79.38
u/l
0.80
688
5646
166
863
2.13
15.75
5.7
4.3
244.71
250.91
u/l
0.18
160
817
70
242
3.05
15.73
1.3
1.3
—
—
—
0
0
115
514
2.42
15.66
2.2
1.7
1.05
1.44
g/l
1.71
108
478
522
3941
1.76
15.23
9.7
7.4
1.21
1.21
mmol/l
0.95
472
3410
134
648
2.25
15.21
4.0
2.9
11.30
10.66
g/l
0.67
121
601
60
194
3.24
15.08
1.9
1.2
37.43
45.16
u/ml
—
7
20
180
990
2.02
14.60
2.6
1.8
—
—
—
0
0
63
214
3.09
14.59
2.3
1.6
—
—
—
0
0
130
632
2.23
14.54
2.8
2.9
66.38
66.92
g/l
0.29
123
584
542
4168
1.74
14.50
9.0
6.6
11.26
11.28
umol/l
0.01
513
3986
475
3532
1.72
14.26
8.5
6.8
1.20
1.21
mmol/l
1.89
454
3252
27
50
5.53
14.07
2.2
2.6
184.10
196.30
e6/l
0.18
20
43
170
938
2.00
13.60
2.6
1.9
—
—
—
0
0
360
2521
1.71
13.17
3.1
2.6
57.37
63.49
u/l
0.55
335
2346
102
475
2.29
12.59
1.3
1.3
44.30
39.98
au/ml
—
5
36
27
56
4.94
12.44
1.5
1.2
—
—
—
0
0
74
300
2.60
12.35
2.6
1.9
1.17
2.33
ug/l
0.50
67
264
57
202
2.94
12.27
2.4
1.6
—
—
—
0
0
687
5773
1.77
12.21
7.5
4.4
13.85
11.73
mm/h
2.96
661
5414
50
166
3.13
12.05
1.3
1.3
297.32
268.88
u/ml
0.21
33
96
107
521
2.19
11.85
2.5
2.5
39.42
18.43
au/ml
—
8
42
200
1230
1.80
11.30
2.7
2.6
2.31
2.32
g/l
0.09
184
1148
136
739
1.99
11.24
2.9
2.3
0.20
0.21
g/l
1.43
121
690
51
180
2.94
11.07
1.9
1.5
—
—
—
0
0
527
4197
1.61
10.84
5.3
3.9
0.00
0.00
estimate
0.50
104
903
45
152
3.06
10.55
1.4
1.4
120.07
150.05
au/ml
0.51
11
49
529
4237
1.59
10.45
5.3
3.9
20.51
1.77
estimate
0.44
108
916
621
5175
1.63
10.33
6.5
4.6
21.50
1231.62
e6/l
—
6
77
334
2407
1.61
10.30
2.8
2.1
164.29
243.05
u/l
0.89
320
2299
42
139
3.12
10.20
2.5
1.7
—
—
—
0
0
174
1066
1.78
9.84
2.9
2.5
115.85
116.63
ug/g
0.01
143
845
206
1329
1.71
9.70
2.9
2.6
13.02
12.95
umol/l
0.05
192
1244
265
1829
1.63
9.63
1.9
1.7
1.00
1.13
mg/l
0.60
209
1412
528
4275
1.56
9.57
5.4
3.9
0.00
0.36
estimate
0.52
104
861
29
79
3.76
9.49
2.4
1.8
—
—
—
0
0
31
89
3.57
9.41
2.4
1.8
—
—
—
0
0
137
793
1.86
9.31
2.2
2.0
315.33
375.70
nmol/l
3.01
129
745
34
105
3.32
9.24
1.5
1.2
—
—
—
0
0
181
1141
1.73
9.23
2.8
2.6
23.15
22.53
%
0.20
168
1078
62
267
2.42
9.14
1.5
1.5
0.01
0.09
iu/ml
0.89
12
45
47
177
2.75
9.09
1.9
1.6
—
—
—
0
0
236
1609
1.63
8.91
1.7
1.6
—
—
—
0
0
171
1073
1.73
8.84
8.5
6.2
1.06
1.05
mmol/l
0.32
160
991
228
1550
1.63
8.68
1.4
1.3
41.12
30.55
iu/ml
0.51
72
478
26
71
3.74
8.49
2.1
1.6
—
—
—
0
0
26
71
3.74
8.49
2.1
1.6
—
—
—
0
0
26
71
3.74
8.49
2.1
1.6
—
—
—
0
0
247
1729
1.59
8.28
1.9
1.4
2.41
2.38
g/l
0.08
178
1068
137
821
1.79
8.28
4.3
4.3
5.98
5.81
kpa
1.31
132
798
132
783
1.80
8.25
4.4
4.4
2.29
1.83
mmol/l
0.84
118
673
61
274
2.31
8.20
2.2
2.6
0.75
1.24
g/l
0.47
54
242
25
69
3.70
8.05
1.3
1.1
—
—
—
0
0
28
84
3.41
7.98
1.3
1.2
—
—
—
0
0
551
4606
1.50
7.86
6.9
5.1
6.58
6.62
mmol/l
0.18
527
4347
90
479
1.98
7.85
8.1
7.3
25.12
24.61
mmol/l
0.65
84
461
40
150
2.74
7.83
1.9
1.5
—
—
—
0
0
38
139
2.81
7.79
1.8
1.2
93.33
111.43
titre
—
6
7
25
72
3.54
7.58
1.3
1.1
—
—
—
0
0
25
72
3.54
7.58
1.3
1.1
—
—
—
0
0
26
77
3.45
7.57
1.3
1.1
—
—
—
0
0
273
2003
1.52
7.27
3.6
2.7
333.55
339.80
umol/l
0.41
238
1778
305
2296
1.49
7.16
1.9
1.7
20.70
20.36
nmol/l
0.14
277
1949
205
1416
1.58
7.15
1.4
1.3
14.68
10.67
u/ml
0.29
79
541
24
70
3.49
7.15
1.3
1.1
—
—
—
0
0
52
234
2.30
6.99
1.4
1.3
—
—
—
0
0
77
405
1.98
6.95
1.8
1.5
—
—
—
0
0
184
1248
1.59
6.92
1.8
1.7
1210.77
1184.40
nmol/l
0.13
144
933
300
2267
1.48
6.85
3.6
3.1
1436.18
1216.88
ng/l
0.37
264
1914
435
3532
1.44
6.81
17.1
13.3
1.23
1.22
inr
0.05
376
2940
33
121
2.79
6.76
1.4
1.6
—
—
—
0
0
39
156
2.57
6.76
1.4
1.5
—
—
—
0
0
68
346
2.04
6.73
1.9
1.8
1.53
1.50
g/l
0.07
62
306
141
903
1.66
6.67
7.1
8.0
1.64
0.99
mmol/l
1.14
116
750
143
920
1.66
6.64
7.2
7.9
11.99
12.24
kpa
0.26
134
890
143
920
1.66
6.64
7.2
7.9
5.07
5.14
kpa
0.42
135
886
242
1767
1.50
6.49
4.1
2.7
5.20
6.16
e6/l
0.49
229
1611
121
750
1.71
6.46
8.0
8.7
120.54
120.77
g/l
0.04
115
737
55
266
2.14
6.23
1.4
1.3
—
—
—
0
0
20
57
3.57
6.18
4.5
2.7
45.00
41.20
%
0.29
11
30
12
14
8.67
6.07
1.3
1.1
—
—
—
0
0
57
283
2.08
6.04
2.5
1.9
—
—
—
0
0
278
2116
1.45
5.97
2.5
2.2
2.76
2.91
mg/l
0.55
241
1811
422
3472
1.40
5.82
2.3
2.1
95.06
96.08
pmol/l
0.17
222
1808
42
188
2.29
5.75
1.8
1.7
—
—
—
0
0
393
3208
1.40
5.62
5.3
3.8
0.00
0.02
estimate
1.87
86
750
582
5074
1.41
5.62
3.6
3.2
—
—
—
0
0
16
42
3.86
5.55
1.6
1.2
—
—
—
0
0
16
42
3.86
5.55
1.6
1.2
—
—
—
0
0
341
2724
1.40
5.51
5.3
3.4
36.70
31.22
u/l
0.34
325
2586
466
3923
1.38
5.49
3.7
3.1
134.00
112.63
ug/l
0.88
438
3678
50
249
2.07
5.29
2.3
2.8
3.86
3.57
g/l
0.68
44
240
24
85
2.87
5.28
1.5
1.2
—
—
—
0
0
48
237
2.08
5.20
1.6
1.3
—
—
—
0
0
51
258
2.03
5.18
3.4
3.9
34.12
56.88
mg/l
0.81
42
223
51
258
2.03
5.18
3.4
3.9
38.88
70.30
mg/l
0.73
42
223
296
2333
1.40
5.09
5.8
4.0
0.00
0.01
estimate
1.34
97
852
185
1339
1.48
5.06
5.2
3.5
0.81
0.82
mmol/l
0.52
176
1265
244
1866
1.42
4.97
6.0
4.0
1.02
1.02
kg/l
0.28
169
1260
26
100
2.65
4.93
2.5
1.6
—
—
—
0
0
429
3608
1.36
4.88
3.1
2.5
75.12
77.14
nmol/l
0.87
397
3270
51
264
1.99
4.87
3.2
2.9
—
—
—
0
0
317
2544
1.38
4.84
5.4
3.4
19.98
79.83
e6/l
1.54
261
1942
47
238
2.03
4.78
1.7
2.4
0.00
0.00
g/l
-0.00
42
207
167
1199
1.48
4.74
2.5
2.1
28.56
29.33
s
1.24
160
1167
79
477
1.72
4.66
2.2
1.6
—
—
—
0
0
45
228
2.02
4.58
1.2
1.4
352.35
302.23
ug/g
0.86
26
135
44
222
2.03
4.53
1.9
1.5
—
—
—
0
0
26
105
2.52
4.49
2.1
1.6
—
—
—
0
0
362
2997
1.34
4.44
5.1
3.7
28.64
68.97
ng/l
1.06
257
2063
45
233
1.98
4.32
3.1
3.6
1.42
4.07
ratio
0.99
30
135
85
535
1.65
4.31
2.8
3.1
156.88
190.78
ng/l
0.42
74
489
676
6156
1.38
4.30
5.0
4.3
14.72
14.72
pmol/l
0.00
638
5652
601
5380
1.34
4.23
4.7
3.3
47.13
45.99
u/l
0.16
573
5085
18
62
2.94
4.19
1.6
1.2
248698.80
238348.03
e6/l
—
10
39
8
10
8.06
4.06
1.0
1.2
—
—
—
0
0
273
2190
1.35
4.05
5.2
3.3
0.39
0.41
e6/l
0.03
212
1603
328
2705
1.33
4.04
4.0
3.4
7.33
7.59
mmol/l
0.51
290
2305
90
585
1.60
4.02
3.5
2.5
6.46
7.38
ug/l
0.22
82
521
18
64
2.85
3.97
1.1
1.0
—
—
—
0
0
30
138
2.21
3.93
1.2
1.3
—
—
—
0
0
14
37
3.83
3.90
2.9
1.7
—
—
—
0
0
14
37
3.83
3.90
2.9
1.7
—
—
—
0
0
14
37
3.83
3.90
2.9
1.7
—
—
—
0
0
14
37
3.83
3.90
2.9
1.7
—
—
—
0
0
178
1342
1.41
3.85
4.5
3.0
0.91
1.00
e6/l
0.21
103
702
25
109
2.33
3.71
1.2
1.2
—
—
—
0
0
249
1993
1.34
3.71
1.5
1.3
1.71
1.54
u/ml
0.09
71
544
810
7669
1.50
3.69
27.8
15.5
22.75
24.12
mg/l
0.67
717
6307
47
262
1.84
3.67
2.1
1.8
—
—
—
0
0
9
16
5.67
3.66
1.2
1.1
89.78
98.38
%
—
9
16
14
45
3.14
3.66
1.4
1.1
—
—
—
0
0
19
73
2.64
3.65
2.3
2.5
—
—
—
0
0
13
35
3.75
3.60
1.2
1.1
401.46
116.94
iu/ml
1.25
13
35
328
2745
1.30
3.54
4.1
3.5
2.34
2.36
mmol/l
1.28
304
2503
39
207
1.92
3.54
1.6
1.3
—
—
—
0
0
126
908
1.45
3.49
4.7
2.9
8.51
8.14
umol/l
0.06
113
797
118
840
1.46
3.49
10.1
6.8
—
—
—
0
0
50
291
1.76
3.41
1.3
1.3
181.88
261.90
miu/ml
0.67
17
142
24
108
2.26
3.34
1.0
1.1
1.51
1.48
g/l
0.09
24
99
37
198
1.91
3.29
2.2
1.5
19361.70
15444.33
e6/l
0.14
30
136
11
28
3.96
3.29
3.5
1.9
—
—
—
0
0
11
28
3.96
3.29
1.8
2.4
41.35
41.15
g/l
0.04
11
28
11
28
3.96
3.29
3.5
1.9
—
—
—
0
0
30
149
2.05
3.28
1.5
1.3
—
—
—
0
0
30
149
2.05
3.28
1.5
1.3
—
—
—
0
0
700
6508
1.33
3.20
29.7
19.0
13.78
13.59
%
3.44
694
6428
11
29
3.83
3.19
3.5
1.9
—
—
—
0
0
199
1573
1.34
3.18
1.7
1.7
42105706.56
35779559.84
pmol/l
0.05
171
1322
13
45
2.92
3.03
1.3
1.2
32.61
18.85
umol/l
0.60
13
39
20
87
2.33
3.02
1.6
1.5
73.17
60.28
%
0.99
12
64
162
1251
1.36
3.01
4.7
3.2
2.55
2.73
e6/l
0.07
81
612
57
359
1.63
2.94
6.7
5.8
1.81
1.53
%
1.18
52
341
63
408
1.58
2.91
1.5
1.3
—
—
—
0
0
109
793
1.43
2.89
4.7
3.3
—
—
—
0
0
49
301
1.66
2.80
2.1
1.6
—
—
—
0
0
298
2528
1.27
2.76
4.3
4.2
17.23
9.21
mg/mmol
0.93
187
1563
11
34
3.26
2.73
1.2
1.3
132.64
189.87
mmol/24h
2.34
11
34
29
153
1.92
2.73
9.1
10.2
104.46
105.33
mmol/l
0.42
24
140
29
153
1.92
2.73
9.1
10.2
11.87
11.19
mmol/l
0.48
24
140
7
14
5.03
2.73
1.3
1.4
—
—
—
0
0
33
182
1.84
2.72
1.5
1.5
3.85
13.24
e6/l
0.96
26
136
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
37
212
1.78
2.71
2.9
3.0
0.33
0.35
iu/ml
0.10
20
122
36
206
1.78
2.65
2.6
3.0
1.39
2.00
index
0.37
18
117
84
593
1.46
2.63
1.8
1.4
—
—
—
0
0
416
3683
1.24
2.61
3.4
2.8
—
—
estimate
—
0
0
7
15
4.69
2.60
1.0
1.0
—
—
—
0
0
181
1454
1.31
2.56
4.6
3.8
274.85
369.70
ng/l
0.24
144
1089
193
1569
1.29
2.50
3.1
2.9
2.45
2.45
mmol/l
0.05
176
1407
84
602
1.44
2.44
3.3
2.7
62.84
67.97
ml/min/173m2
0.51
37
259
237
1983
1.26
2.43
6.2
4.1
88.45
91.45
%
1.28
228
1941
9
27
3.36
2.39
1.2
1.1
—
—
—
0
0
8
22
3.66
2.36
1.0
1.8
—
—
—
0
0
15
65
2.33
2.32
1.5
1.7
—
—
—
0
0
63
432
1.49
2.30
10.0
10.5
16.28
15.69
%
1.02
58
417
42
263
1.63
2.27
1.6
1.4
—
—
—
0
0
26
142
1.86
2.25
1.5
1.4
0.69
0.36
nmol/l
0.34
20
113
31
179
1.76
2.25
2.6
1.4
—
—
—
0
0
44
280
1.60
2.24
2.4
2.1
281.22
415.99
ug/l
0.33
39
264
19
93
2.07
2.22
2.3
1.3
—
—
—
0
0
5
9
5.58
2.21
5.2
1.8
—
—
—
0
0
42
265
1.61
2.21
2.0
2.5
98.17
93.93
%
0.61
42
253
10
35
2.88
2.21
6.0
2.9
1.65
1.31
%
—
10
35
85
623
1.40
2.20
5.2
4.2
87.43
85.38
ng/l
0.08
76
555
19
95
2.02
2.11
2.3
1.3
—
—
—
0
0
19
95
2.02
2.11
2.3
1.3
—
—
—
0
0
24
131
1.85
2.09
3.8
3.5
0.98
0.86
nmol/l
0.29
16
107
14
62
2.28
2.08
1.5
1.2
1.27
0.83
u/ml
—
9
29
15
69
2.19
2.05
1.9
1.4
—
—
—
0
0
9
32
2.83
2.00
1.4
1.5
—
—
—
0
0
35
218
1.63
1.96
1.3
1.2
—
—
—
0
0
35
218
1.63
1.96
1.3
1.2
—
—
—
0
0
99
759
1.34
1.96
2.9
2.4
37.70
35.82
u/l
0.15
87
636
12
51
2.37
1.95
1.8
1.2
11.08
11.87
u/l
0.08
12
46
754
7210
1.26
1.95
6.1
5.3
1.90
1.89
mu/l
0.09
718
6696
44
292
1.53
1.91
1.5
1.6
8.23
7.81
u/ml
—
6
67
64
459
1.42
1.90
5.0
4.0
2.58
1.87
mmol/l
1.04
50
342
224
1915
1.22
1.86
2.9
2.3
—
—
—
0
0
128
1030
1.28
1.80
2.7
2.2
—
—
—
0
0
118
943
1.29
1.76
2.5
2.0
—
—
—
0
0
80
605
1.35
1.75
2.7
2.1
—
—
—
0
0
25
147
1.72
1.75
1.6
2.0
4.54
4.93
mmol/24h
0.23
19
129
6
18
3.35
1.75
1.5
1.2
—
—
—
0
0
9
36
2.51
1.74
1.9
1.2
—
—
—
0
0
9
36
2.51
1.74
1.9
1.2
—
—
—
0
0
8
30
2.68
1.72
3.0
2.9
0.64
0.60
mmol/l
—
8
30
57
412
1.41
1.65
1.3
1.4
24.25
24.98
iu/l
0.06
51
352
67
498
1.37
1.65
3.0
3.5
4.48
4.56
pmol/l
0.23
59
445
5
14
3.58
1.61
1.4
1.2
—
—
—
0
0
17
91
1.88
1.61
2.5
1.4
—
—
—
0
0
13
63
2.08
1.60
2.9
1.4
0.81
1.23
promille
—
7
51
804
7787
1.27
1.59
28.6
18.1
3.95
3.96
mmol/l
0.92
795
7623
7
26
2.70
1.58
1.3
1.1
—
—
—
0
0
802
7773
1.26
1.52
28.4
17.9
139.25
139.68
mmol/l
5.07
794
7622
14
72
1.96
1.49
1.6
1.2
96.50
110.46
pmol/l
0.68
14
72
51
369
1.40
1.49
1.7
1.6
0.42
0.31
mg/l
0.49
20
165
11
52
2.13
1.45
1.5
1.4
—
—
—
0
0
66
503
1.34
1.41
2.6
2.0
—
—
—
0
0
6
23
2.62
1.37
1.2
1.0
—
—
—
0
0
14
75
1.88
1.35
3.9
1.6
—
—
—
0
0
828
8074
1.28
1.34
19.4
11.7
26.45
25.71
u/l
0.55
813
7862
265
2366
1.17
1.34
4.6
3.3
0.00
0.05
estimate
0.80
88
731
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
42
2.15
1.34
1.1
1.2
—
—
—
0
0
11
54
2.05
1.33
1.3
1.2
—
—
—
0
0
81
642
1.29
1.33
2.7
2.4
11.22
12.90
nmol/l
1.07
74
589
9
43
2.10
1.30
1.3
1.1
—
—
—
0
0
16
91
1.77
1.29
2.6
1.4
—
—
—
0
0
5
18
2.79
1.28
1.4
1.3
—
—
—
0
0
12
62
1.95
1.28
1.2
1.2
—
—
—
0
0
12
62
1.95
1.28
1.2
1.2
—
—
—
0
0
16
92
1.75
1.25
2.6
1.3
—
—
—
0
0
6
25
2.41
1.24
1.0
1.1
—
—
—
0
0
12
63
1.92
1.23
1.1
1.1
—
—
—
0
0
742
7173
1.18
1.21
6.7
6.2
38.46
38.93
mmol/mol
0.91
711
6745
8
39
2.06
1.15
2.3
1.7
78.00
64.86
ug/l
—
8
39
20
126
1.60
1.15
1.2
1.1
—
1.13
—
0
5
11
58
1.91
1.12
1.5
1.6
—
—
—
0
0
119
1007
1.21
1.12
2.0
1.8
1.41
1.45
%
0.23
99
897
8
40
2.01
1.12
1.3
1.1
1408.12
1526.30
miu/ml
—
8
40
7
33
2.13
1.05
1.4
1.2
—
—
—
0
0
7
33
2.13
1.05
1.1
1.0
—
—
—
0
0
44
332
1.34
1.05
1.9
2.1
7852.12
6722.65
u/l
0.06
13
144
9
46
1.97
1.03
1.2
1.4
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
9
47
1.92
1.02
1.2
1.4
—
—
—
0
0
13
76
1.72
0.99
1.6
1.4
6.45
6.12
mmol/l
0.26
13
70
25
173
1.46
0.98
1.2
1.1
0.82
3.62
u/ml
1.91
15
97
5
23
2.18
0.98
2.0
1.1
125.00
99.29
%
—
5
17
103
1206
0.84
0.96
3.3
3.2
0.84
0.78
ug/l
0.17
75
767
14
86
1.64
0.91
3.4
3.5
—
—
—
0
0
16
103
1.56
0.88
1.3
1.3
—
—
—
0
0
6
30
2.01
0.87
4.3
1.5
—
—
—
0
0
6
31
1.94
0.84
1.0
1.1
—
—
—
0
0
8
46
1.75
0.82
1.0
1.2
—
—
—
0
0
60
491
1.24
0.82
8.2
9.0
24.88
24.42
mmol/l
0.58
60
481
8
48
1.67
0.79
2.6
1.8
91.14
108.87
ng/l
—
8
48
12
74
1.63
0.78
1.1
1.1
—
—
—
0
0
28
208
1.36
0.78
4.5
2.9
1.49
1.55
mmol/l
0.17
28
203
16
107
1.50
0.76
1.8
1.4
240.09
361.81
pmol/l
0.84
11
95
18
124
1.46
0.75
1.2
1.2
5.10
5.73
u/ml
—
10
52
7
38
1.85
0.73
2.3
2.3
—
—
—
0
0
26
194
1.35
0.72
2.8
2.2
126.00
128.75
g/l
0.22
21
156
5
27
1.86
0.68
1.4
1.2
8.56
8.87
ug/l
—
5
27
18
127
1.43
0.68
1.2
1.2
3.44
4.73
u/ml
—
9
40
14
94
1.50
0.67
1.2
1.4
0.14
0.19
nmol/l
—
9
68
7
44
1.60
0.65
1.6
1.4
—
—
—
0
0
7
44
1.60
0.65
1.6
1.4
—
—
—
0
0
5
29
1.73
0.64
1.4
1.6
—
—
—
0
0
5
29
1.73
0.64
3.6
5.1
—
—
—
0
0
15
104
1.45
0.62
5.0
2.3
33.33
32.69
pg
0.26
15
104
91
804
1.15
0.58
3.1
4.5
10.87
27.14
ug/l
0.64
73
662
149
1363
1.11
0.55
1.7
1.5
—
—
—
0
0
19
146
1.31
0.47
1.6
1.7
—
—
—
0
0
7
49
1.43
0.46
1.6
1.7
—
—
—
0
0
345
3311
1.07
0.42
2.1
1.9
1.27
1.35
mmol/l
1.46
300
2826
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
25
206
1.22
0.38
1.3
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.4
167.62
175.88
pmol/l
—
6
44
6
47
1.28
0.32
2.3
3.0
0.33
0.91
index
—
6
47
6
47
1.28
0.32
1.5
1.4
—
—
—
0
0
12
92
1.31
0.32
3.1
2.6
106.33
105.40
mmol/l
0.14
12
92
12
92
1.31
0.32
3.1
2.6
3.82
4.03
mmol/l
1.10
12
92
12
92
1.31
0.32
3.1
2.6
1.19
1.19
mmol/l
0.15
12
92
7
53
1.32
0.31
2.4
1.5
—
—
—
0
0
36
315
1.15
0.30
1.4
1.2
0.84
0.90
g/l
1.12
36
315
81
878
0.92
0.30
1.9
2.0
3.34
3.54
ratio
0.83
60
702
30
259
1.16
0.30
1.5
1.5
11.14
9.40
u/l
0.26
25
205
7
55
1.27
0.30
2.4
1.9
—
—
—
0
0
15
122
1.23
0.27
1.0
1.1
—
—
—
0
0
154
1615
0.94
0.25
4.7
4.5
20.69
21.49
%
0.24
75
756
24
208
1.16
0.24
1.3
1.4
257.79
214.30
pmol/l
0.12
24
202
26
228
1.14
0.23
1.6
2.1
3.73
4.40
iu/l
—
9
94
7
91
0.77
0.22
1.0
1.1
101.71
97.05
%
—
7
84
843
8380
1.08
0.22
38.8
23.4
250.84
252.24
e9/l
0.25
835
8220
196
2033
0.95
0.22
6.2
5.3
2.63
2.31
ug/l
0.17
178
1835
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
843
8382
1.08
0.21
38.7
23.4
4.39
4.50
e12/l
7.20
832
8206
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
0.62
—
0
13
54
582
0.92
0.20
1.2
1.2
53.87
144.60
u/ml
2.91
23
239
741
7349
1.04
0.18
22.2
14.7
83.79
82.73
ml/min/173m2
0.62
683
6775
23
204
1.13
0.18
1.2
1.6
—
—
—
0
0
13
111
1.17
0.16
1.7
1.6
—
—
—
0
0
33
304
1.09
0.14
1.1
1.1
1.63
1.55
g/l
0.68
33
304
31
286
1.09
0.13
1.0
1.1
0.47
0.69
ratio
—
7
35
16
180
0.89
0.13
1.4
1.7
—
—
—
0
0
12
104
1.16
0.12
1.3
1.1
—
—
—
0
0
45
424
1.06
0.12
1.1
1.0
—
—
—
0
0
741
7374
1.03
0.09
5.9
4.9
5.87
5.89
mmol/l
0.17
693
6792
6
58
1.03
0.08
1.0
1.0
—
—
—
0
0
33
313
1.06
0.07
4.0
3.5
362.47
4637.16
u/ml
0.75
28
272
770
7673
1.02
0.07
6.1
5.6
2.72
2.73
mmol/l
0.17
730
7165
63
650
0.97
0.07
1.6
1.7
3.42
3.51
mmol/l
0.26
41
474
27
256
1.06
0.06
2.1
1.8
39.44
39.87
nmol/l
0.03
27
242
34
325
1.05
0.06
2.4
1.8
6.30
3.21
mg/l
0.58
29
241
21
223
0.94
0.06
1.5
1.5
1.39
1.13
ratio
0.41
15
143
21
223
0.94
0.06
1.5
1.5
0.89
0.98
ratio
0.77
15
143
21
223
0.94
0.06
1.5
1.5
1.32
1.19
ratio
0.30
15
143
21
221
0.95
0.04
1.5
1.5
—
—
—
0
0
759
7572
1.01
0.04
5.5
5.0
4.62
4.66
mmol/l
0.57
727
7096
31
302
1.03
0.02
1.8
1.5
—
—
—
0
0
15
143
1.05
0.01
1.3
1.1
1.08
1.79
u/ml
—
9
75
719
7198
0.99
0.01
4.6
4.2
1.29
1.28
mmol/l
0.09
678
6655
27
276
0.98
0.00
1.5
1.4
—
—
—
0
0
95
956
0.99
0.00
4.8
4.7
33.47
32.08
%
0.55
70
644
15
148
1.01
0.00
1.3
1.5
70.51
51.49
ug/l
0.97
15
148
755
7547
1.00
0.00
5.3
4.9
1.47
1.47
mmol/l
0.14
716
7035
16
157
1.02
0.00
4.2
3.5
10.33
8.72
pmol/l
0.20
16
157
10
99
1.01
0.00
1.3
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
6.12
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.6
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
6
62
0.97
-0.00
1.2
1.0
237.83
227.13
mg/l
—
6
52
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_ERYTHEMAMULTIF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ERYTHEMAMULTIF | 1.578 [1.37, 1.82] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.068 |
During the follow-up period (1.1.1998 — 31.12.2019), 521 out of 2889 females with L12_ERYTHEMAMULTIF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ERYTHEMAMULTIF | 1.557 [1.32, 1.83] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 415 out of 2388 males with L12_ERYTHEMAMULTIF died.
Mortality risk
Mortality risk for people of age
years, who have L12_ERYTHEMAMULTIF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.167% | 0.238% |
| 5 | 0.852% | 1.464% |
| 10 | 2.022% | 3.826% |
| 15 | 3.886% | 7.226% |
| 20 | 6.825% | 12.223% |
Relationships between endpoints
↥Index endpoint: L12_ERYTHEMAMULTIF – Erythema multiforme
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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