Congenital obstructive defects of renal pelvis and congenital malformations of ureter

Q17_CONGEN_OBSTRUCTIVE_DEFECTS_RENAL_PELVIS_CONGEN_MALFO_URETER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q62
  • Cause of death: ICD-10 Q62

2 out of 7 registries used, show all original rules.

843

4. Check minimum number of events

None

843

5. Include endpoints

None

843

6. Filter based on genotype QC (FinnGen only)

758

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_URINARY_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q6[0-4]
Name in latin
Defectus obstructivi congeniti pelvis renalis

Similar endpoints

List of similar endpoints to Congenital obstructive defects of renal pelvis and congenital malformations of ureter based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10797 5507 5270
Only index persons 8505 4638 3867
Unadjusted period prevalence (%)
Whole population 0.15 0.16 0.15
Only index persons 0.16 0.17 0.15
Median age at first event (years)
Whole population 2.92 4.58 1.05
Only index persons 4.71 6.19 2.94

-FinnGen-

Key figures

All Female Male
Number of individuals 758 495 263
Unadjusted period prevalence (%) 0.16 0.18 0.12
Median age at first event (years) 27.43 26.21 29.73

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
798
Matched controls
7979
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q62.10
ICD-10 Finland
Congenital unilateral occlusion of the pelvic ureteral junction
+∞
307.7
310
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
60.5
307.7
214
48
Q62.7
ICD-10 Finland
Congenital vesico-uretero-renal reflux
3248.9
269.5
245
*
UKC02
NOMESCO Finland
Cystoscopy
12.2
250.7
321
418
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
62.1
247.3
139
27
N13.0
ICD-10 Finland
Hydronephrosis with ureteropelvic junction obstruction
145.2
246.1
123
10
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
14.8
207.1
207
184
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
9.1
191.3
305
507
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
35.3
190.5
123
41
KA1FN
NOMESCO Finland
Isotope renography
67.8
154.5
85
14
J01EA01
ATC
trimethoprim; systemic
5.6
127.1
393
1187
KA1AE
NOMESCO Finland
Kidney ultrasound examination
20.4
125.5
99
55
G04AC01, ,
ATC
17.2
124.4
107
71
Q62.0
ICD-10 Finland
Congenital hydronephrosis
+∞
122.1
114
*
KAH41
NOMESCO Finland
Percutaneous endoscopic pyeloureteroplasty with division of ureteropelvic junction
1326.1
120.1
114
*
1530
FHL
Urethrocystoscopy
30.8
117.0
78
28
J01XE01
ATC
nitrofurantoin; oral
21.4
96.7
74
38
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
31.9
94.4
62
21
KBV52
NOMESCO Finland
Cystoscopic injection therapy for vesicourethral reflux
+∞
92.5
87
*
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
34.0
79.3
51
16
5901A
ICD-9 Finland
Infections of kidney, Acute pyelonephritis
38.3
75.6
47
13
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
40.6
75.2
46
12
Q62.5
ICD-10 Finland
Duplication of ureter
+∞
72.0
68
*
N20.0
ICD-10 Finland
Calculus of kidney
17.8
70.0
58
35
204
Kela drug reimbursment
Leukemia lymphatica
11.6
69.9
75
71
N18.8
ICD-10 Finland
Other chronic renal failure
16.8
68.1
58
37
XKD00
NOMESCO Finland
Uroflowmetry
5.2
64.0
152
348
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
5.2
61.7
142
316
KH1AD
NOMESCO Finland
CT of urinary organs
8.8
58.5
77
96
N13.7
ICD-10 Finland
Vesicoureteral-reflux-associated uropathy
77.0
57.0
64
9
Z94.0
ICD-10 Finland
Kidney transplant status
17.0
56.8
48
30
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.8
56.1
217
715
5937A
ICD-9 Finland
Other disorders of kidney and ureter, Vesicoureteric reflux
196.6
53.7
55
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
12.0
53.2
55
49
J01MA02
ATC
ciprofloxacin; systemic
3.1
52.1
343
1558
UKB02
NOMESCO Finland
Retrograde ureteroscopy
68.0
49.9
57
9
Q62.18
ICD-10 Finland
Other specified atresia and stenosis of ureter
+∞
48.4
46
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
12.7
48.3
48
40
KBH20
NOMESCO Finland
Replantation of ureter
81.1
47.6
53
7
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
47.3
240
929
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
14.6
47.1
43
31
ZXE20
NOMESCO Finland
More than three and less than five hours
3.8
45.3
162
500
A11CC03
ATC
alfacalcidol; systemic
9.7
45.3
54
59
KAH40
NOMESCO Finland
Pyeloureteroplasty with division of ureteropelvic junction
+∞
45.2
43
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
44.4
293
1311
U14
ICPC
Kidney symptom/complaint
14.6
42.7
39
28
XKC03
NOMESCO Finland
Water cystometry
8.5
42.3
56
70
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
17.4
42.1
35
21
127
Kela drug reimbursment
Transplant complication
9.8
41.3
49
53
KC1JB
NOMESCO Finland
Miktiocystography with X-ray
417.7
40.5
40
*
KH1AA
NOMESCO Finland
Urinary tract X-ray examination without contrast
12.7
40.4
40
33
A12AA04
ATC
calcium carbonate; oral
13.7
40.2
38
29
Q62.2
ICD-10 Finland
Congenital megaloureter
+∞
37.8
36
*
ZXC96
NOMESCO Finland
Robot assisted procedure
9.6
36.8
44
48
L04AD02
ATC
tacrolimus; systemic
10.7
35.4
39
38
L04AA06
ATC
mycophenolic acid; systemic
8.4
34.4
46
58
5910A
ICD-9 Finland
Hydronephrosis[HYDRONEPHROSIS]
351.4
34.2
34
*
Q62.3
ICD-10 Finland
Other obstructive defects of renal pelvis and ureter
+∞
33.6
32
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
5.7
33.1
64
120
N30.0
ICD-10 Finland
Acute cystitis
2.8
32.3
213
930
N13.9
ICD-10 Finland
Obstructive and reflux uropathy, unspecified
91.5
32.0
35
*
R4110
NOMESCO Finland
Physiotherapy
2.5
31.7
271
1344
KA3GB
NOMESCO Finland
Retrograde pyelography
313.7
30.0
30
*
KH1EE
NOMESCO Finland
Urologic ultrasound examination
52.2
29.6
35
7
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
28.8
333
1873
KA3EB
NOMESCO Finland
Antegrade pyelography
80.6
28.0
31
*
TK800
NOMESCO Finland
Hemodialysis
9.5
27.5
33
36
R50.9
ICD-10 Finland
Fever, unspecified
2.6
27.3
191
852
Q62.11
ICD-10 Finland
Congenital bilateral occlusion of the pelvic ureteral junction
+∞
27.2
26
*
N18.0
ICD-10 Finland
End-stage renal disease
64.4
27.1
31
5
N13.1
ICD-10 Finland
Hydronephrosis with ureteral stricture, not elsewhere classified
62.2
26.1
30
5
KBV10
NOMESCO Finland
Removal of stent from ureter
28.1
26.0
35
13
B03XA02
ATC
darbepoetin alfa; parenteral
9.0
25.5
32
37
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
25.4
159
669
R31
ICD-10 Finland
Unspecified haematuria
3.5
24.8
90
276
N20.1
ICD-10 Finland
Calculus of ureter
6.0
24.4
44
77
Q62.8
ICD-10 Finland
Other congenital malformations of ureter
+∞
24.1
23
*
Q64.2
ICD-10 Finland
Congenital posterior urethral valves
+∞
24.1
23
*
TKC20
NOMESCO Finland
Catheterisation of bladder
4.1
23.6
67
173
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
22.9
23.2
33
15
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.8
23.0
75
214
KBV00
NOMESCO Finland
Insertion of stent into ureter
28.3
22.4
30
11
KH1CB
NOMESCO Finland
Urography with X-ray
+∞
20.9
20
*
KBV15
NOMESCO Finland
Cystoscopic change of ureteral stent
42.9
20.5
25
6
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
20.5
287
1694
WX402
NOMESCO Finland
General anaesthesia
2.2
20.3
222
1191
TPH07
NOMESCO Finland
Cathetrisation of artery
2.9
19.8
101
379
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
194.4
18.6
19
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
18.1
18.3
28
16
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
15.8
18.1
29
19
ZXE00
NOMESCO Finland
One hour or less
1.9
18.0
333
2147
N20.9
ICD-10 Finland
Urinary calculus, unspecified
6.2
17.4
30
50
KAE12
NOMESCO Finland
Retrograde ureteronephroscopic lithotripsy in pelvis of kidney
32.3
17.1
22
7
J01DA01
ATC
[U] cefalexin
1.9
16.9
460
3339
N28.8
ICD-10 Finland
Other specified disorders of kidney and ureter
35.9
16.7
21
6
Q62.12
ICD-10 Finland
Congenital occlusion of ureterovesical orifice
+∞
16.7
16
*
Q62.6
ICD-10 Finland
Malposition of ureter
+∞
16.7
16
*
KAH62
NOMESCO Finland
Endopyelotomy
+∞
16.7
16
*
N30.9
ICD-10 Finland
Cystitis, unspecified
2.9
16.3
81
299
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
19.0
16.1
24
13
ZXD05
NOMESCO Finland
Urgent procedure
2.0
15.7
244
1470
ZXA00
NOMESCO Finland
Right side
2.1
15.1
180
984
Z3226
NOMESCO Finland
Physiotherapist
2.1
15.1
168
895
V03AE01
ATC
polystyrene sulfonate; oral
14.3
15.1
25
18
KAC00
NOMESCO Finland
Nephrectomy
32.4
14.9
19
6
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
18.8
14.7
22
12
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
11.6
14.4
26
23
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
22.7
14.3
20
9
N02AX02
ATC
tramadol; systemic, rectal
1.8
14.1
278
1796
TKC22
NOMESCO Finland
Catheterisation instruction
6.2
13.9
24
40
XF602
NOMESCO Finland
Bloodpressure monitoring
6.6
13.7
22
34
7143
FHL
Pyeloureteroplasty
76.5
13.6
15
*
KAH30
NOMESCO Finland
Pyeloureteroplasty without division of ureteropelvic junction
+∞
13.6
13
*
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
10.3
13.5
26
26
Z3231
NOMESCO Finland
Registered nurse
1.9
13.5
239
1490
L04AD01
ATC
ciclosporin; systemic
5.0
13.4
29
60
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.5
13.3
46
136
Z2221
NOMESCO Finland
Medical doctor
1.9
13.3
226
1389
196
Kela drug reimbursment
Paricalcitol and cinacalcet
28.9
13.0
17
6
J01MA06
ATC
norfloxacin; oral
2.5
12.9
88
381
J01CA08
ATC
pivmecillinam; oral
1.7
12.9
337
2353
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
32.6
12.6
16
5
Q61.0
ICD-10 Finland
Congenital single renal cyst
+∞
12.5
12
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.3
12.5
47
147
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
24.8
12.5
17
7
7187
FHL
Ureterohydroplasty due to reflux, for example
132.0
12.5
13
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
12.4
327
2283
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
14.6
12.3
20
14
137
Kela drug reimbursment
Uraemia requiring dialysis
11.3
12.1
22
20
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
27.2
12.1
16
6
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
12.0
116
582
ZXA05
NOMESCO Finland
Left side
2.0
11.9
155
868
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
11.9
174
1014
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.7
11.7
37
103
J01MA12
ATC
levofloxacin; systemic
2.1
11.7
119
609
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
16.7
11.7
18
11
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
11.5
77
330
KCW98
NOMESCO Finland
Other transluminal endoscopic operation on bladder
121.7
11.5
12
*
B03XA01
ATC
erythropoietin; parenteral
12.0
11.4
20
17
5990B
ICD-9 Finland
Other disorders of urethra and urinary tract, Urinary tract infection, site not specified[INFECTIO VIARUM URINARIUM ACUTA]
15.3
11.3
18
12
WX704
NOMESCO Finland
Intubation
2.5
11.2
70
290
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
11.1
123
651
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
15.8
10.9
17
11
RD210, ,
NOMESCO Finland
3.5
10.8
37
109
7219
FHL
Other measure in this category
60.8
10.6
12
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
10.5
309
2194
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.6
10.5
25
56
KBV42
NOMESCO Finland
Cystoscopic incision or excision of ureterocele
111.4
10.4
11
*
N13.8
ICD-10 Finland
Other obstructive and reflux uropathy
111.4
10.4
11
*
Q60.3
ICD-10 Finland
Renal hypoplasia, unilateral
+∞
10.4
10
*
Q60.0
ICD-10 Finland
Renal agenesis, unilateral
+∞
10.4
10
*
KCF02
NOMESCO Finland
Transluminal endoscopic removal of foreign body from bladder
+∞
10.4
10
*
KDD52
NOMESCO Finland
Urethroscopic excision of urethral valve
+∞
10.4
10
*
N19
ICD-10 Finland
Unspecified kidney failure
4.0
10.4
29
74
7532A
ICD-9 Finland
Congenital anomalies of urinary system, Obstructive defects of renal pelvis and ureter
33.0
10.4
13
*
V03AE03
ATC
lanthanum carbonate; oral
26.4
9.8
13
5
N30
ICD-10 Finland
Cystitis
2.2
9.8
88
428
V03AE02
ATC
sevelamer; oral
20.3
9.8
14
7
G04BD04
ATC
oxybutynin; oral, transdermal
2.8
9.7
49
182
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.9
9.7
28
73
N26
ICD-10 Finland
Unspecified contracted kidney
55.7
9.7
11
*
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
55.7
9.7
11
*
N13.2
ICD-10 Finland
Hydronephrosis with renal and ureteral calculous obstruction
55.7
9.7
11
*
7534X
ICD-9 Finland
Congenital anomalies of urinary system, Other specified anomalies of ureter
101.2
9.4
10
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
17.8
9.4
14
8
B34.9
ICD-10 Finland
Viral infection, unspecified
2.7
9.4
52
203
Q61.40
ICD-10 Finland
Renal dysplasia of a kidney (multicystic)
+∞
9.4
9
*
7186
FHL
Ureteroplasty, narrowing and resection (includes neoimplantation)
+∞
9.4
9
*
Q61.1
ICD-10 Finland
Polycystic kidney, autosomal recessive
+∞
9.4
9
*
5990C
ICD-9 Finland
Other disorders of urethra and urinary tract, Urinary tract infection, site not specified[INFECTIO VIARUM URINARIUM RECIDIVANS]
22.0
9.4
13
6
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
4.8
9.3
21
45
WX892
NOMESCO Finland
Monitored bed care
2.4
9.1
62
268
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
11.6
9.1
16
14
H05BX01
ATC
cinacalcet; oral
15.8
9.1
14
9
R39.1
ICD-10 Finland
Other difficulties with micturition
3.9
9.0
26
68
R32
ICD-10 Finland
Unspecified urinary incontinence
3.8
8.9
27
73
KH1DD
NOMESCO Finland
CT urography of urinary organs
24.3
8.9
12
5
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
8.9
111
610
R33
ICD-10 Finland
Retention of urine
2.8
8.9
45
168
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.5
8.8
56
234
KDV20
NOMESCO Finland
Submucous urethral injection
50.5
8.7
10
*
ZXD20
NOMESCO Finland
Day surgery
2.0
8.6
98
522
UKA02
NOMESCO Finland
Retrograde ureteronephroscopy
20.3
8.5
12
6
Z99.2
ICD-10 Finland
Dependence on renal dialysis
20.3
8.5
12
6
WX725
NOMESCO Finland
Noninvasive ventilation
2.7
8.5
46
178
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
8.4
69
324
Q62.1
ICD-10 Finland
Atresia and stenosis of ureter
+∞
8.3
8
*
7533X
ICD-9 Finland
Congenital anomalies of urinary system, Other specified anomalies of kidney
+∞
8.3
8
*
3076C
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Enuresis[YÖ- JA PÄIVÄKASTELU]
+∞
8.3
8
*
SPAT1255
SPAT
Intravenous administration of medicine
2.7
8.2
45
175
U07
ICPC
Urine symptom/complaint other
2.2
8.2
69
327
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.0
8.2
23
59
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
8.2
77
382
WZC30
NOMESCO Finland
Teaching
1.9
8.2
111
628
N28.1
ICD-10 Finland
Cyst of kidney
8.2
8.1
17
21
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
8.1
87
454
WX199
NOMESCO Finland
Other local analgesia
3.6
8.0
26
74
C08CA01
ATC
amlodipine; oral
1.7
8.0
184
1213
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
2.8
7.9
38
138
F98.02
ICD-10 Finland
Non-organic nocturnal and diurnal enuresis
7.5
7.7
17
23
R4190
NOMESCO Finland
Nutritional therapy
2.3
7.7
58
263
J01DB01
ATC
cefalexin; oral
1.7
7.7
637
5613
J01MA01
ATC
ofloxacin; systemic
2.5
7.6
46
188
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
7.6
62
290
H02AB04
ATC
methylprednisolone; systemic
2.0
7.6
91
493
KH1YT
NOMESCO Finland
Percutaneous implantation of endoprothesis with radiological guidance
25.3
7.6
10
*
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
9.0
7.6
15
17
B05DB
ATC
Hypertonic solutions
9.0
7.6
15
17
602
Kela drug reimbursment
Children's severe malnutrition
4.3
7.5
19
45
D41.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Ureter
80.8
7.4
8
*
KAC20
NOMESCO Finland
Nephroureterectomy
80.8
7.4
8
*
KBV32
NOMESCO Finland
Cystoscopic incision of ureteric orifice
80.8
7.4
8
*
Q42.2
ICD-10 Finland
Congenital absence, atresia and stenosis of anus with fistula
80.8
7.4
8
*
Q61.99
ICD-10 Finland
Cystic kidney disease, unspecified
80.8
7.4
8
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.7
7.4
39
149
B05DA
ATC
Isotonic solutions
8.5
7.3
15
18
U28
ICPC
Limited function/disability (U)
9.5
7.3
14
15
N13.4
ICD-10 Finland
Hydroureter
+∞
7.3
7
*
7536A
ICD-9 Finland
Congenital anomalies of urinary system, Atresia and stenosis of urethra and bladder neck[OBSTRUCTIO URETHRAE ET COLLI VESICAE CONGENITA]
+∞
7.3
7
*
KBV04
NOMESCO Finland
Laparoscopic insertion of stent into ureter
+∞
7.3
7
*
KBJ00
NOMESCO Finland
Cutaneous ureterostomy
+∞
7.3
7
*
59199
ICD-8 Finland
Hydronephrosis
+∞
7.3
7
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.5
7.3
25
74
C03CA01
ATC
furosemide; systemic
1.7
7.1
134
836
U05
ICPC
Urination problems other
2.6
7.0
40
159
ZX120
NOMESCO Finland
Intravenous
2.1
7.0
71
362
L04AA01
ATC
[U] ciclosporin
7.1
7.0
16
23
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.8
7.0
33
119
GD1AD
NOMESCO Finland
Thorax CT examination
2.5
6.9
41
166
RS220, ,
NOMESCO Finland
4.0
6.9
19
48
Z2446
NOMESCO Finland
Social worker
2.0
6.9
78
414
U99
ICPC
Urinary disease other
13.9
6.9
11
8
L04AX01
ATC
azathioprine; systemic
2.6
6.9
39
155
205
Kela drug reimbursment
Chronic hypertension
1.8
6.8
110
655
U13
ICPC
Bladder symptom/complaint other
3.1
6.8
28
93
5604
FHL
Vascular preparation or cannulation in the operating room
16.9
6.8
10
6
TK810
NOMESCO Finland
Hemofiltration
16.9
6.8
10
6
5AB14, ,
NOMESCO Finland
12.4
6.6
11
9
K06.18
ICD-10 Finland
Another gingival hyperplasia
6.9
6.5
15
22
Z50.1
ICD-10 Finland
Other physical therapy
2.6
6.5
36
141
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
6.5
107
642
G04CA02
ATC
tamsulosin; oral
1.9
6.5
84
468
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.4
6.5
23
70
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
6.4
593
5210
H05BX02
ATC
paricalcitol; systemic
70.4
6.4
7
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.4
65
332
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
14.4
6.4
10
7
59010
ICD-8 Finland
Infections of kidney, Pyelonephritis
5.2
6.3
18
35
N18
ICD-10 Finland
Chronic kidney disease
11.1
6.3
11
10
7188
FHL
Ureteroneocystostomy
+∞
6.3
6
*
Q62.4
ICD-10 Finland
Agenesis of ureter
+∞
6.3
6
*
Q61.48
ICD-10 Finland
Nonspecified renal dysplasia
+∞
6.3
6
*
Q63.2
ICD-10 Finland
Ectopic kidney
+∞
6.3
6
*
KAD10
NOMESCO Finland
Heminephrectomy
+∞
6.3
6
*
N13.5
ICD-10 Finland
Kinking and stricture of ureter without hydronephrosis
+∞
6.3
6
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
6.2
204
1455
Z49.2
ICD-10 Finland
Other dialysis
7.8
6.1
13
17
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
7.8
6.1
13
17
U70
ICPC
Pyelonephritis/pyelitis
4.2
6.1
16
39
B01AB10
ATC
tinzaparin; parenteral
1.9
6.1
71
381
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
8.7
6.1
12
14
N28.9
ICD-10 Finland
Disorder of kidney and ureter, unspecified
10.1
6.0
11
11
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
6.0
56
277

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
421
2126
3.07
53.16
8.6
3.3
154.87
42.00
e6/l
0.40
347
1566
383
1862
3.03
51.32
8.2
3.1
0.16
0.36
e6/l
2.11
308
1320
321
1421
3.11
50.73
6.4
2.6
6.90
7.79
e6/l
0.31
300
1286
270
1087
3.24
50.17
6.2
3.0
3.52
2.67
e6/l
0.54
164
503
279
1151
3.19
49.66
5.9
2.9
0.72
0.80
e6/l
0.28
173
566
462
2567
2.90
47.13
10.3
3.9
76.90
64.94
e6/l
0.27
359
1679
386
1975
2.85
45.68
5.3
2.7
—
—
—
0
0
284
1238
3.01
45.23
6.5
2.7
544.05
549.59
mosm/kgh2o
0.16
262
1087
147
450
3.78
41.39
11.2
4.5
100.61
70.37
ng/l
3.19
138
415
43
41
11.03
39.61
49.3
41.4
6.92
6.73
ug/l
0.26
38
36
74
143
5.60
37.10
2.3
2.7
—
—
—
0
0
35
28
13.03
35.97
3.1
2.1
—
—
—
0
0
374
2086
2.49
34.51
4.9
2.8
0.00
0.13
—
6
24
642
4644
2.96
33.54
9.3
4.3
—
2.41
—
0
5
184
741
2.93
32.55
8.1
7.6
104.85
104.27
mmol/l
1.03
184
741
619
4464
2.72
31.19
9.7
4.4
198.00
1849.08
e6/l
1.00
19
61
201
886
2.70
29.68
20.3
7.4
1.15
1.13
mmol/l
0.37
193
834
460
2998
2.26
27.54
6.0
3.3
6.24
6.25
ph
0.06
253
1616
528
3710
2.25
25.36
7.1
3.7
0.04
0.01
estimate
0.37
97
740
524
3671
2.24
25.35
7.1
3.6
0.04
6.46
estimate
1.06
99
776
520
3650
2.22
24.77
7.1
3.6
0.00
0.00
estimate
-0.00
95
783
405
2585
2.15
24.57
10.2
5.5
35.94
37.06
g/l
3.75
390
2439
154
679
2.57
22.17
5.1
4.7
1.66
1.74
%
0.43
147
624
150
659
2.57
21.72
15.0
10.1
—
—
—
0
0
345
2149
2.07
21.49
2.8
2.4
—
—
—
0
0
291
1762
2.03
19.08
10.0
3.7
7.39
7.39
ph
2.57
215
1223
157
748
2.37
18.89
13.0
6.5
7.37
7.38
ph
1.65
119
463
435
3039
1.95
18.68
18.8
7.6
1.22
1.22
mmol/l
0.30
410
2661
153
726
2.37
18.55
13.2
6.6
1.18
1.59
mmol/l
0.88
136
607
116
491
2.59
17.96
3.1
3.7
66.35
72.17
e9/l
1.01
80
341
437
3107
1.90
17.28
3.3
2.9
—
—
estimate
—
0
0
361
2419
1.90
17.09
10.6
9.8
1.16
1.16
inr
0.08
295
2009
120
552
2.38
15.46
9.2
9.6
0.22
0.85
mmol/l
1.07
94
463
41
102
4.18
15.13
9.2
2.6
9.35
7.38
pmol/l
0.57
41
102
119
551
2.36
15.09
9.3
9.6
7.42
7.41
ph
0.21
54
295
247
1513
1.92
14.97
6.9
4.2
—
—
—
0
0
389
2751
1.81
14.83
18.2
7.5
1.22
1.22
mmol/l
0.40
376
2559
118
553
2.33
14.53
9.4
9.5
14.05
12.96
kpa
1.07
110
535
118
553
2.33
14.53
9.4
9.5
4.96
5.16
kpa
1.75
110
533
181
1020
2.00
13.88
6.5
2.5
12.33
13.94
umol/l
2.75
176
944
160
869
2.05
13.56
7.1
2.5
20.98
23.15
%
1.49
155
813
25
24
10.71
13.31
4.4
2.6
—
—
—
0
0
255
1631
1.83
13.21
2.8
2.4
—
—
—
0
0
487
3759
1.76
13.07
8.2
5.3
6.31
6.35
mmol/l
0.14
449
3460
61
227
2.83
12.07
2.9
1.6
—
—
—
0
0
305
2107
1.72
11.86
5.6
3.5
7.20
8.16
mmol/l
3.02
286
1831
58
213
2.86
11.76
2.9
1.6
133.60
128.41
au/ml
0.12
25
71
421
3180
1.69
11.68
6.4
6.4
11.85
11.74
umol/l
0.04
399
3001
15
5
30.52
11.67
8.2
2.2
5.78
10.28
mmol/l
—
15
5
66
265
2.62
11.29
2.4
1.5
220.83
221.32
u/ml
0.00
41
138
296
2084
1.67
10.41
5.8
2.9
0.25
0.01
estimate
0.47
80
639
367
2733
1.63
10.31
6.6
3.4
0.00
0.02
estimate
1.56
82
657
570
4745
1.70
10.25
11.2
7.5
86.92
81.76
u/l
1.32
558
4491
37
113
3.38
10.24
8.6
2.9
—
—
—
0
0
57
226
2.64
10.00
1.9
2.4
1.58
1.41
g/l
0.61
50
205
99
504
2.10
9.84
10.5
10.0
96.99
95.73
%
2.17
94
490
233
1560
1.70
9.80
5.5
3.6
88.69
55.09
mg/l
1.68
182
1041
61
253
2.53
9.77
6.6
5.2
290.66
289.07
mg/l
0.01
47
127
212
1392
1.71
9.55
4.4
3.0
350.90
325.54
umol/l
2.72
200
1249
299
2149
1.63
9.49
8.4
6.8
—
—
—
0
0
41
142
2.99
9.25
3.1
2.1
128.09
129.51
g/l
0.15
35
115
498
4066
1.60
9.07
12.5
10.1
4.06
3.92
e9/l
0.73
432
3520
232
1582
1.66
8.99
6.3
4.3
16.38
9.89
mg/mmol
1.61
178
1017
36
118
3.15
8.92
1.3
1.3
—
—
—
0
0
685
6088
1.88
8.91
30.4
16.9
13.46
13.32
%
2.07
679
6020
133
782
1.84
8.68
3.2
3.9
8.57
6.87
umol/l
0.26
115
663
429
3404
1.56
8.68
10.6
7.5
8.84
8.53
%
1.45
410
3222
426
3386
1.55
8.47
10.7
7.5
0.66
0.67
%
0.07
407
3197
439
3520
1.55
8.34
10.4
7.3
28.97
30.27
%
1.66
421
3371
426
3397
1.54
8.27
10.6
7.4
2.85
2.85
%
0.00
407
3211
721
6561
2.02
8.10
29.0
14.6
139.62
139.58
mmol/l
0.18
713
6401
432
3468
1.54
8.04
10.0
7.2
55.85
55.12
%
0.65
418
3339
388
3045
1.53
8.01
4.1
2.7
70.70
71.99
nmol/l
0.54
380
2811
721
6569
2.01
7.95
29.4
14.6
3.98
3.93
mmol/l
4.60
711
6387
43
169
2.63
7.71
4.0
3.2
2.56
3.30
index
0.33
27
99
265
1927
1.56
7.65
3.7
2.6
63.73
61.08
u/l
0.28
253
1785
741
6834
2.18
7.65
25.0
13.3
25.65
21.68
mg/l
2.70
644
5374
305
2296
1.53
7.50
3.4
3.4
30.12
30.57
u/l
0.12
293
2176
36
135
2.75
7.08
7.9
9.3
1.23
1.18
mmol/l
0.12
30
114
318
2441
1.50
7.01
9.8
7.4
—
—
—
0
0
445
3657
1.49
6.99
10.2
7.3
0.57
0.55
e9/l
0.96
385
3128
152
986
1.67
6.96
9.4
5.1
0.79
0.81
mmol/l
2.93
146
938
166
1104
1.64
6.89
4.1
3.6
136.93
535.72
ng/l
2.12
120
702
445
3664
1.48
6.88
10.2
7.3
0.04
0.04
e9/l
0.63
386
3139
456
3780
1.48
6.77
10.4
7.7
0.19
0.19
e9/l
0.39
403
3292
92
523
1.86
6.64
3.1
2.1
6.16
6.28
ph
0.59
59
332
274
2058
1.50
6.62
5.8
3.2
2.36
2.36
mmol/l
0.15
256
1886
102
600
1.80
6.60
3.0
3.1
0.22
0.22
g/l
0.04
97
566
458
3814
1.47
6.54
4.9
3.3
85.71
82.44
ug/l
0.22
441
3603
136
870
1.68
6.54
2.1
2.1
—
—
—
0
0
14
20
7.10
6.24
2.3
2.6
0.60
0.62
mmol/l
0.54
14
20
108
659
1.74
6.16
2.7
2.4
44.31
30.46
u/l
0.80
95
542
451
3774
1.45
6.09
10.3
7.3
1.95
2.03
e9/l
0.67
398
3325
61
313
2.03
5.95
6.6
4.9
0.64
0.61
%
0.31
61
313
18
49
3.73
5.94
5.1
3.9
0.72
0.78
index
0.10
18
49
175
1230
1.54
5.66
2.4
1.6
—
—
—
0
0
67
363
1.92
5.61
19.7
7.8
9.83
9.34
kpa
1.78
67
351
54
272
2.06
5.55
4.9
2.9
1.02
1.02
ratio
0.55
47
252
14
24
5.92
5.54
3.1
2.9
518.21
520.40
min
0.03
14
15
250
1914
1.45
5.26
2.3
1.8
—
—
—
0
0
30
120
2.56
5.26
2.0
1.8
—
—
—
0
0
30
120
2.56
5.26
2.0
1.8
—
—
—
0
0
30
120
2.56
5.26
2.0
1.8
—
—
—
0
0
30
120
2.56
5.26
2.0
1.8
—
—
—
0
0
93
572
1.71
5.16
16.0
6.6
7.41
7.41
ph
0.17
87
462
86
518
1.74
5.14
2.2
1.4
—
—
—
0
0
29
116
2.56
5.09
6.6
3.8
—
—
—
0
0
477
4105
1.40
5.07
3.8
3.4
—
0.14
—
0
7
121
803
1.60
4.99
1.7
1.5
—
—
—
0
0
222
1678
1.45
4.96
6.5
3.6
1.02
1.02
kg/l
4.09
169
1070
14
29
4.89
4.82
3.3
2.9
648.57
476.38
ml
0.85
14
16
14
29
4.89
4.82
1.1
1.2
—
—
—
0
0
68
393
1.80
4.69
2.5
3.1
65.38
66.91
g/l
0.84
68
371
57
317
1.86
4.45
3.2
4.5
20.77
21.30
s
0.34
52
301
27
113
2.44
4.35
9.1
3.0
1.51
2.46
mmol/l
1.18
15
65
23
90
2.60
4.25
5.4
4.0
1.83
1.33
%
0.17
23
83
16
51
3.18
4.22
1.9
2.6
1.20
1.19
mmol/l
0.71
16
51
12
25
4.86
4.19
1.3
1.8
143.83
141.86
mmol/24h
0.03
12
25
74
454
1.69
4.16
1.7
1.5
—
—
—
0
0
51
281
1.87
4.11
10.5
7.8
23.31
24.58
mmol/l
1.64
45
267
16
52
3.12
4.10
1.9
2.6
107.00
105.92
mmol/l
0.42
16
52
16
52
3.12
4.10
1.9
2.6
4.13
3.95
mmol/l
0.84
16
52
235
1855
1.38
3.98
2.9
2.4
2.87
2.70
mg/l
0.34
204
1614
29
133
2.22
3.84
1.9
1.6
20.07
24.80
ng/l
0.56
29
133
112
776
1.52
3.82
1.2
1.2
—
—
—
0
0
49
274
1.84
3.79
1.5
1.3
—
—
—
0
0
7
8
8.81
3.78
1.7
1.4
264.57
295.00
umol/24h
—
7
8
23
96
2.44
3.75
4.4
2.5
7.57
7.19
mmol/l
0.14
23
89
14
40
3.54
3.62
2.2
2.5
1.25
2.42
u/field
—
8
26
14
40
3.54
3.62
3.9
3.8
853.00
1118.43
mg
0.32
14
40
740
7051
1.68
3.60
19.8
11.2
—
—
—
0
0
46
258
1.83
3.54
9.1
6.1
—
—
—
0
0
88
589
1.56
3.52
3.3
2.0
0.00
0.00
estimate
-0.00
19
136
288
2389
1.32
3.43
1.9
2.0
—
—
—
0
0
31
154
2.05
3.39
2.7
2.1
9.79
10.50
g/l
0.52
31
144
16
59
2.75
3.34
1.3
1.6
—
—
—
0
0
205
1629
1.35
3.25
1.7
1.6
19.68
20.17
nmol/l
0.23
181
1398
15
55
2.76
3.16
4.0
3.1
0.73
0.85
nmol/l
0.30
15
43
24
111
2.20
3.15
4.0
2.5
112.17
93.91
ug/min
0.10
17
66
69
451
1.58
3.07
17.9
7.1
—
—
—
0
0
8
16
5.04
3.05
6.5
10.4
45.00
46.59
%
—
8
16
25
120
2.12
3.01
4.5
2.4
1.28
1.49
mmol/l
1.22
25
112
11
31
3.58
3.00
1.1
1.1
—
—
—
0
0
11
32
3.47
2.90
1.1
1.0
—
—
—
0
0
26
129
2.05
2.89
5.6
3.7
26.22
28.04
mg/l
0.11
21
89
175
1381
1.34
2.88
3.6
3.6
1981.63
884.80
ng/l
1.48
154
1136
239
1980
1.30
2.77
7.7
3.7
0.00
0.01
estimate
1.15
85
739
602
5600
1.30
2.67
6.5
5.2
37.27
37.65
mmol/mol
0.49
580
5311
11
35
3.17
2.65
2.4
1.3
—
—
—
0
0
24
120
2.03
2.63
2.7
4.0
1.78
2.44
ratio
0.39
14
65
43
262
1.68
2.56
1.1
1.5
—
7.60
—
0
8
40
240
1.70
2.52
1.3
1.2
—
—
—
0
0
134
1038
1.35
2.48
1.4
1.4
341.67
536.75
titre
1.48
24
191
14
57
2.48
2.46
1.0
1.2
83.93
111.09
pmol/l
1.68
14
57
43
268
1.64
2.37
2.4
1.7
1.14
1.17
g/l
0.32
43
255
8
22
3.66
2.37
1.0
1.0
—
—
—
0
0
46
293
1.60
2.33
2.2
2.6
—
—
—
0
0
42
262
1.64
2.31
2.4
1.7
0.23
0.22
g/l
0.24
42
250
33
194
1.73
2.26
3.1
3.3
373.29
1000.06
u/ml
0.38
24
167
53
353
1.54
2.23
1.6
1.6
—
—
—
0
0
105
799
1.36
2.19
1.3
1.2
—
—
—
0
0
106
811
1.35
2.14
1.3
1.2
—
—
—
0
0
39
244
1.63
2.14
1.7
1.2
—
—
—
0
0
107
822
1.35
2.11
2.2
1.7
—
—
—
0
0
29
168
1.75
2.10
1.1
1.2
—
—
—
0
0
153
1242
1.29
2.04
2.6
2.8
104.55
113.00
ug/g
0.16
120
993
12
50
2.42
2.03
1.4
1.1
—
—
—
0
0
291
2545
1.23
2.02
2.0
1.9
95.44
97.27
pmol/l
0.27
153
1338
650
6175
1.28
2.01
5.4
4.7
2.60
2.72
mmol/l
2.95
630
5832
293
2571
1.22
1.96
2.0
1.9
1.28
1.31
mmol/l
0.24
273
2216
58
406
1.46
1.96
1.2
1.2
—
—
—
0
0
51
348
1.50
1.95
1.6
1.5
—
—
—
0
0
65
466
1.43
1.94
2.3
2.3
17.13
15.60
au/ml
—
6
48
272
2381
1.22
1.84
2.7
2.3
—
—
—
0
0
18
94
1.94
1.81
1.2
1.2
—
—
—
0
0
369
3330
1.20
1.81
15.9
10.9
0.00
0.00
e9/l
0.21
294
2689
9
35
2.59
1.80
2.8
1.6
—
—
—
0
0
23
132
1.76
1.75
2.1
1.9
—
—
—
0
0
84
644
1.34
1.70
1.2
1.3
95.53
136.10
u/ml
0.91
29
242
498
4634
1.20
1.70
3.6
3.4
37.95
36.83
u/l
0.17
476
4423
64
470
1.39
1.69
1.6
1.6
66.76
61.45
ug/l
0.38
55
421
48
336
1.46
1.65
1.6
1.5
1.28
1.26
mm
0.11
39
256
134
1101
1.26
1.63
3.8
2.5
2.44
2.43
mmol/l
0.39
117
977
10
42
2.40
1.62
1.2
3.3
—
—
—
0
0
42
288
1.48
1.60
3.4
1.8
—
—
—
0
0
61
450
1.38
1.58
3.9
4.4
6.10
16.51
ug/l
0.53
51
359
771
7559
1.59
1.58
35.3
20.2
255.08
258.46
e9/l
0.82
763
7399
638
6098
1.23
1.56
4.9
4.2
1.44
1.46
mmol/l
0.47
618
5754
13
64
2.05
1.54
4.7
5.1
—
—
—
0
0
771
7564
1.57
1.51
35.2
20.1
4.50
4.56
e12/l
2.24
761
7382
771
7565
1.56
1.49
35.3
20.2
6.79
6.74
e9/l
0.34
762
7379
9
38
2.38
1.46
1.1
1.1
357.29
145.98
iu/ml
—
9
38
61
458
1.36
1.44
1.9
1.6
37.99
18.31
iu/l
1.86
47
358
45
321
1.43
1.43
4.0
2.0
0.00
0.00
estimate
-0.00
13
115
20
118
1.71
1.42
1.2
1.3
5.80
3.87
u/ml
—
10
54
7
29
2.43
1.39
2.7
3.1
—
—
—
0
0
13
67
1.96
1.39
1.0
1.2
35.70
37.66
mg/l
0.09
13
51
61
462
1.35
1.37
1.8
1.6
363.14
310.52
mu/l
0.24
56
419
639
6132
1.21
1.37
5.0
4.3
4.47
4.59
mmol/l
2.88
621
5815
5
17
2.95
1.36
4.8
1.6
120.10
92.48
ng/l
—
5
17
11
54
2.05
1.33
1.0
1.3
0.70
0.61
ratio
—
6
28
61
465
1.34
1.32
3.6
3.6
4.46
4.72
pmol/l
1.37
55
421
131
1101
1.23
1.32
1.7
1.7
103390283.63
28709079.70
pmol/l
0.32
118
937
6
24
2.51
1.30
2.7
2.3
2411.67
2464.38
ml
—
6
24
267
2399
1.17
1.29
1.7
1.7
—
—
—
0
0
59
762
0.76
1.27
1.2
1.3
—
—
—
0
0
13
70
1.87
1.24
1.9
2.0
32.92
32.19
pg
0.35
13
70
33
229
1.46
1.23
1.1
1.2
—
—
—
0
0
5
19
2.64
1.21
1.0
1.1
4.73
6.31
mg/g
—
5
19
10
50
2.01
1.17
1.6
4.3
—
—
—
0
0
656
6337
1.20
1.16
5.7
5.2
1.93
1.84
mu/l
1.01
630
5940
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
5
20
2.51
1.15
1.0
1.2
19.22
16.35
umol/l
—
5
15
11
58
1.91
1.12
1.0
1.1
—
—
—
0
0
7
31
2.27
1.10
2.7
3.0
—
—
—
0
0
7
32
2.20
1.08
1.9
2.5
—
—
—
0
0
7
32
2.20
1.08
3.3
3.5
—
—
—
0
0
68
544
1.27
1.08
7.2
5.2
0.00
0.16
%
1.41
27
127
95
791
1.23
1.07
2.0
1.8
—
—
—
0
0
71
572
1.26
1.06
3.2
2.8
0.71
0.69
ug/l
0.08
51
334
597
5739
1.16
1.04
4.3
3.6
1.21
1.21
mmol/l
0.06
576
5383
15
90
1.68
1.04
1.0
1.3
59.60
26.74
u/l
0.29
15
77
611
5892
1.16
0.99
4.9
4.1
5.68
5.71
mmol/l
0.26
579
5446
718
7018
1.23
0.98
15.0
10.5
24.66
25.76
u/l
1.02
709
6830
14
84
1.68
0.98
2.4
2.1
—
—
—
0
0
6
27
2.23
0.93
3.5
1.4
0.00
0.00
estimate
—
6
27
65
529
1.25
0.92
7.2
4.5
0.86
0.60
%
0.26
29
150
165
1470
1.15
0.88
2.4
2.4
2.13
1.13
mg/l
0.66
131
1097
220
2004
1.13
0.85
3.6
3.3
149.29
67.85
ng/l
0.30
120
1178
8
45
1.79
0.84
2.1
1.8
5.25
5.95
mmol/l
—
8
33
22
154
1.44
0.84
7.2
3.8
24.22
23.49
nmol/l
0.08
22
148
11
65
1.70
0.82
1.2
1.3
—
—
nmol/l
—
0
0
186
1680
1.14
0.82
2.2
2.2
150.88
215.39
u/l
0.83
180
1601
100
865
1.18
0.79
1.6
1.6
1088.69
960.51
mu/l
0.75
91
772
20
140
1.44
0.77
1.1
1.1
5.31
2.14
eliau/ml
—
8
57
113
990
1.16
0.77
5.5
4.9
2.08
2.07
ug/l
0.01
106
886
21
149
1.42
0.76
1.3
1.7
0.40
0.71
g/l
1.66
16
125
10
59
1.70
0.76
1.0
1.1
—
—
—
0
0
10
59
1.70
0.76
1.3
1.3
—
—
—
0
0
7
38
1.85
0.73
1.7
1.5
—
—
—
0
0
40
318
1.27
0.72
2.4
1.9
5.67
5.58
iu/ml
—
6
66
19
134
1.43
0.71
1.3
1.1
—
—
—
0
0
220
2026
1.12
0.71
1.6
1.5
1.98
2.07
g/l
0.40
133
1229
567
5489
1.11
0.69
4.9
4.3
14.72
14.58
pmol/l
0.74
539
5019
65
549
1.20
0.68
7.5
4.9
0.50
1.06
%
1.59
28
159
44
357
1.25
0.68
1.3
1.3
—
—
—
0
0
24
179
1.35
0.67
1.4
1.3
248.65
333.76
ug/g
1.17
17
102
244
2268
1.11
0.67
1.5
1.5
1.16
1.94
u/ml
1.03
61
568
20
145
1.39
0.66
1.3
1.1
—
—
—
0
0
33
260
1.28
0.65
2.4
2.3
—
—
—
0
0
5
29
1.73
0.64
1.6
2.2
200.40
109.06
ug/l
—
5
29
8
49
1.64
0.62
1.1
1.2
138.71
191.71
pmol/l
—
8
49
30
235
1.29
0.62
1.1
1.1
12.64
8.89
eliau/ml
—
7
40
162
1480
1.12
0.61
1.7
1.7
—
—
—
0
0
29
227
1.29
0.60
1.7
2.1
2.60
4.32
iu/l
—
10
94
61
522
1.18
0.58
7.8
5.0
0.04
0.13
%
1.06
25
130
92
814
1.15
0.58
3.2
3.1
3.78
4.90
e9/l
1.53
85
730
52
440
1.19
0.56
1.5
1.3
250.22
244.19
miu/ml
0.04
27
222
13
90
1.45
0.55
3.2
2.8
35.09
40.22
%
0.64
13
90
9
60
1.51
0.54
2.2
3.3
3.76
3.06
nmol/l
—
9
60
6
39
1.54
0.53
1.2
1.4
68.83
68.13
umol/l
—
6
39
11
75
1.47
0.51
1.2
1.2
—
—
—
0
0
13
93
1.40
0.48
2.2
1.4
—
—
—
0
0
7
48
1.46
0.47
1.1
1.1
1345.00
1617.42
miu/ml
—
7
48
76
676
1.14
0.46
1.4
1.4
—
—
—
0
0
27
219
1.24
0.45
1.2
1.2
—
—
—
0
0
23
183
1.26
0.45
1.1
2.3
414.61
206.88
e6/l
0.36
18
137
7
50
1.40
0.45
4.3
2.1
15.14
36.56
mg/l
—
7
36
16
121
1.33
0.44
1.1
1.1
—
—
—
0
0
28
229
1.23
0.44
2.6
3.0
6.02
6.90
umol/l
0.21
22
176
7
51
1.38
0.44
1.1
1.1
—
0.30
—
0
6
182
1704
1.09
0.44
8.7
4.6
—
—
—
0
0
43
499
0.85
0.43
1.3
1.2
—
—
—
0
0
77
691
1.13
0.42
1.6
1.4
—
—
—
0
0
8
58
1.38
0.41
1.4
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
7.8
—
—
—
0
0
0
17
0.00
0.40
0.0
1.9
—
—
—
0
0
75
674
1.12
0.40
2.4
2.4
10064.28
5641.70
u/l
0.56
31
259
29
241
1.21
0.40
1.4
1.7
39.66
39.03
nmol/l
0.06
29
234
5
34
1.47
0.40
1.0
1.3
—
—
—
0
0
16
124
1.30
0.39
6.6
3.5
3.16
3.92
e9/l
0.78
16
124
11
80
1.38
0.38
1.0
1.8
—
—
—
0
0
10
72
1.39
0.37
1.2
1.2
—
—
—
0
0
22
180
1.23
0.36
1.1
2.3
1.88
10.30
e6/l
1.32
17
130
10
73
1.37
0.34
1.6
1.4
39.68
38.58
nmol/l
—
10
64
35
303
1.16
0.33
1.2
1.1
0.84
0.87
g/l
0.48
35
303
12
92
1.31
0.32
1.0
1.3
1.86
2.80
u/ml
—
7
53
7
53
1.32
0.31
1.3
1.2
—
—
—
0
0
66
604
1.10
0.28
9.0
3.4
—
—
—
0
0
41
366
1.13
0.27
2.2
2.4
12.71
5.78
ug/l
0.81
36
324
23
197
1.17
0.26
1.2
1.1
—
—
—
0
0
23
198
1.17
0.25
1.2
1.1
—
—
—
0
0
12
96
1.25
0.24
1.3
3.3
—
—
—
0
0
11
87
1.27
0.24
1.5
1.3
—
—
—
0
0
5
39
1.28
0.23
3.2
2.7
9.59
10.98
mg/l
—
5
33
7
93
0.75
0.22
1.6
1.6
0.54
0.48
e9/l
—
7
93
5
41
1.22
0.22
1.0
1.0
10.84
9.78
mu/l
—
5
35
54
498
1.09
0.21
2.1
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
51
470
1.09
0.21
8.3
3.8
7.40
7.34
ph
1.50
45
343
0
13
0.00
0.21
0.0
26.9
—
0.52
—
0
13
33
297
1.12
0.20
1.1
1.1
1.58
1.53
g/l
0.54
33
297
6
48
1.25
0.20
1.2
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
4.19
—
0
8
32
288
1.12
0.20
1.7
1.6
4.92
8.13
u/ml
—
5
66
11
90
1.23
0.19
1.5
1.7
—
—
—
0
0
33
363
0.91
0.18
1.6
1.6
—
—
—
0
0
7
58
1.21
0.18
1.3
1.1
—
—
—
0
0
14
119
1.18
0.17
1.1
1.1
—
—
—
0
0
169
1635
1.04
0.17
2.0
2.0
—
—
—
0
0
8
70
1.14
0.16
1.1
1.1
—
—
—
0
0
17
149
1.14
0.15
1.4
1.1
—
—
—
0
0
31
338
0.91
0.15
2.3
2.6
—
—
—
0
0
27
294
0.92
0.13
1.1
1.2
1.49
1.34
u/ml
0.07
18
172
27
294
0.92
0.13
1.1
1.2
5.67
2.14
u/ml
0.90
19
189
83
798
1.04
0.12
1.7
1.6
—
—
—
0
0
21
191
1.10
0.12
7.3
2.8
53.10
56.33
%
0.45
21
191
74
771
0.96
0.11
2.0
1.9
—
—
—
0
0
70
671
1.05
0.11
1.6
1.6
3.30
3.36
mmol/l
0.15
49
450
31
332
0.93
0.11
1.1
1.2
0.42
3.52
u/ml
4.78
19
213
74
769
0.96
0.10
2.0
2.0
—
—
—
0
0
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
51
533
0.95
0.09
2.1
2.7
—
—
—
0
0
75
776
0.96
0.09
2.0
1.9
—
—
—
0
0
6
54
1.11
0.09
1.3
1.7
—
—
—
0
0
33
349
0.94
0.08
1.2
1.1
—
—
—
0
0
33
312
1.06
0.08
1.1
1.1
—
—
—
0
0
5
62
0.81
0.08
1.0
1.0
—
—
—
0
0
5
63
0.79
0.08
1.4
1.0
—
—
—
0
0
122
1248
0.97
0.08
1.3
1.3
15.30
24.78
iu/ml
1.80
32
343
6
72
0.83
0.07
1.0
1.4
—
—
—
0
0
75
772
0.97
0.07
2.0
2.0
—
—
—
0
0
10
89
1.13
0.07
1.0
1.3
—
—
—
0
0
8
92
0.87
0.06
1.1
1.2
—
—
—
0
0
22
234
0.94
0.06
1.1
1.1
18.77
6.09
u/ml
0.95
17
141
18
168
1.07
0.06
1.2
2.4
—
—
—
0
0
10
91
1.10
0.04
1.1
1.7
—
—
—
0
0
12
129
0.93
0.03
1.0
1.1
—
—
—
0
0
38
391
0.97
0.03
1.8
1.6
0.28
0.25
mg/l
0.11
17
164
60
611
0.98
0.03
1.8
2.0
—
—
—
0
0
18
172
1.05
0.02
6.2
8.4
—
—
—
0
0
263
2617
1.01
0.02
2.8
2.7
—
—
—
0
0
21
217
0.97
0.01
1.1
1.1
9.01
7.59
u/ml
0.11
13
122
72
722
1.00
0.00
2.0
2.0
—
—
—
0
0
14
144
0.97
0.00
1.7
1.7
—
2832.00
—
0
5
80
797
1.00
0.00
1.6
1.6
1292.55
1186.34
nmol/l
0.28
63
608
17
165
1.03
0.00
1.5
1.8
228.24
210.19
pmol/l
0.25
17
159
115
1153
1.00
0.00
1.3
1.3
13.01
7.98
u/ml
0.26
40
436
16
164
0.97
0.00
1.4
1.3
—
—
—
0
0
39
386
1.01
0.00
1.9
1.7
15.16
7.86
u/l
0.85
30
290
21
212
0.99
0.00
1.1
1.1
2.84
1.19
u/ml
—
9
90
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
7
77
0.91
0.00
3.3
4.8
—
—
—
0
0
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
427.31
—
0
7
0
9
0.00
0.00
0.0
3.3
—
32.67
—
0
9
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
6
61
0.98
0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
1.3
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
8
87
0.92
-0.00
1.4
2.4
—
—
—
0
0
6
62
0.97
-0.00
1.2
1.3
0.86
1.23
promille
—
6
48
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.0
—
0.20
—
0
8
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_CONGEN_OBSTRUCTIVE_DEFECTS_RENAL_PELVIS_CONGEN_MALFO_URETER and mortality.

Females

Parameter HR [95% CI] p-value
Q17_CONGEN_OBSTRUCTIVE_DEFECTS_RENAL_PELVIS_CONGEN_MALFO_URETER 1.465 [1.2, 1.79] < 0.001
Birth year 0.993 [0.98, 1.0] 0.145

During the follow-up period (1.1.1998 — 31.12.2019), 184 out of 4672 females with Q17_CONGEN_OBSTRUCTIVE_DEFECTS_RENAL_PELVIS_CONGEN_MALFO_URETER died.

Males

Parameter HR [95% CI] p-value
Q17_CONGEN_OBSTRUCTIVE_DEFECTS_RENAL_PELVIS_CONGEN_MALFO_URETER 1.668 [1.31, 2.13] < 0.001
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 136 out of 4660 males with Q17_CONGEN_OBSTRUCTIVE_DEFECTS_RENAL_PELVIS_CONGEN_MALFO_URETER died.

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_OBSTRUCTIVE_DEFECTS_RENAL_PELVIS_CONGEN_MALFO_URETER.

N-year risk Females Males
1 0.093% 0.297%
5 0.765% 1.81%
10 1.936% 4.479%
15 3.673% 8.582%
20 6.517% 15.033%

Relationships between endpoints

Index endpoint: Q17_CONGEN_OBSTRUCTIVE_DEFECTS_RENAL_PELVIS_CONGEN_MALFO_URETER – Congenital obstructive defects of renal pelvis and congenital malformations of ureter

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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