Other articular cartilage disorders

M13_CARTILAGE

cartilage disease: Softening and degeneration of the CARTILAGE. Pathological processes involving the chondral tissue (CARTILAGE).

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M24.1
  • Hospital discharge: ICD-9 7180
  • Hospital discharge: ICD-8 7249
  • Cause of death: ICD-10 M24.1
  • Cause of death: ICD-9 7180
  • Cause of death: ICD-8 7249

2 out of 7 registries used, show all original rules.

1010

4. Check minimum number of events

None

1010

5. Include endpoints

None

1010

6. Filter based on genotype QC (FinnGen only)

930

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M24
Name in latin
Alia vitia cartilaginum articularium

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7026 3215 3754
Only index persons 6071 2847 3224
Unadjusted period prevalence (%)
Whole population 0.10 0.09 0.10
Only index persons 0.11 0.10 0.12
Median age at first event (years)
Whole population 37.19 39.65 34.93
Only index persons 35.55 37.92 33.46

-FinnGen-

Key figures

All Female Male
Number of individuals 930 455 475
Unadjusted period prevalence (%) 0.19 0.16 0.22
Median age at first event (years) 35.29 34.33 36.22

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
950
Matched controls
9500
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M17.1
ICD-10 Finland
Other primary gonarthrosis
28.6
307.7
345
186
M24.1
ICD-10 Finland
Other articular cartilage disorders
+∞
307.7
302
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
22.4
302.1
240
141
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
54.0
280.2
162
36
1220
FHL
Arthroscopy
45.8
277.5
167
44
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
80.6
257.7
138
20
72498
ICD-8 Finland
Internal derangement of joint, Alio loco definito
+∞
232.1
213
*
72499
ICD-8 Finland
Internal derangement of joint, Derangement of other joints
+∞
224.1
206
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
22.2
203.7
157
84
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
194.7
180
*
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
17.5
188.9
164
112
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
38.0
186.5
117
35
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
14.0
183.6
183
159
7180F
ICD-9 Finland
Other derangement of joint, Articular cartilage disorder[NIVELRUSTON SAIRAUS,POLVI]
+∞
182.3
169
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
22.2
165.4
126
65
M01AX05
ATC
glucosamine; oral
6.8
133.6
250
472
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
70.7
132.0
72
11
M09AX01
ATC
hyaluronic acid; parenteral
22.8
124.8
93
45
1221
FHL
Arthroscopy and meniscus surgery
48.9
109.4
64
14
1223
FHL
Arthroscopy and articular cartilage surgery
1139.7
106.5
102
*
M25.5
ICD-10 Finland
Pain in joint
4.4
104.3
379
1239
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
+∞
104.1
98
*
L90
ICPC
Osteoarthrosis of knee
13.7
103.3
100
81
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
186.0
97.3
100
6
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
53.0
95.7
55
11
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
41.6
90.6
55
14
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
6.7
88.7
156
271
M20.1
ICD-10 Finland
Hallux valgus (acquired)
15.4
87.0
78
55
M13.9
ICD-10 Finland
Arthritis, unspecified
13.5
84.8
82
66
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
+∞
80.4
76
*
N02AX02
ATC
tramadol; systemic, rectal
3.5
80.2
524
2454
1225
FHL
Arthroscopy and other therapeutic procedure
39.7
79.7
49
13
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
8.2
76.5
108
147
WX320
NOMESCO Finland
Spinalanesthesy
4.1
75.1
262
808
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
14.5
74.8
69
51
L15
ICPC
Knee symptom/complaint
3.8
70.1
276
922
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
17.6
69.9
58
35
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
27.4
68.4
47
18
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
14.3
67.9
63
47
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.2
67.7
494
2404
M22.4
ICD-10 Finland
Chondromalacia patellae
125.8
65.8
70
6
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
84.0
63.0
70
9
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
8.8
61.5
80
98
M23.8
ICD-10 Finland
Other internal derangements of knee
16.0
60.9
53
35
M01AH01
ATC
celecoxib; oral
3.9
60.9
216
666
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
6.3
56.7
102
179
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.2
56.2
307
1239
M01AH05
ATC
etoricoxib; oral
3.0
55.1
648
3949
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
5.3
54.6
119
250
L04AX03
ATC
methotrexate; systemic
6.9
51.9
84
132
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
50.5
48
*
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
+∞
49.4
47
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
6.0
49.3
92
167
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
5.0
48.2
111
244
B01AB05
ATC
enoxaparin; parenteral
2.8
45.8
320
1455
ZXA05
NOMESCO Finland
Left side
3.0
45.6
266
1098
N03AX12
ATC
[U] gabapentin; oral
3.4
45.5
192
655
B01AF01
ATC
rivaroxaban; oral
4.1
45.2
139
383
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
45.2
43
*
ZXA00
NOMESCO Finland
Right side
2.9
45.1
277
1175
M79.6
ICD-10 Finland
Pain in limb
2.6
44.8
449
2438
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
84.3
43.3
48
6
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.8
43.0
149
446
P01BA02
ATC
hydroxychloroquine; oral
7.7
42.4
61
84
N03AX16
ATC
[U] pregabalin
2.9
42.2
254
1062
S83.2
ICD-10 Finland
Tear of meniscus, current
5.2
39.8
87
182
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
10.0
39.7
46
48
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
39.2
433
2419
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
208.5
39.1
40
*
84400
ICD-8 Finland
Sprains and strains of knee and leg
12.3
38.7
39
33
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.3
36.4
159
550
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
35.6
34
*
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
33.5
32
*
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
13.2
33.3
32
25
WX111
NOMESCO Finland
Local infiltration anesthesia
93.5
32.9
36
*
M10.9
ICD-10 Finland
Gout, unspecified
5.3
32.4
68
137
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
10.4
32.0
36
36
M01AC06
ATC
meloxicam; systemic, rectal
2.3
31.1
347
1904
N02BE01
ATC
paracetamol; systemic, rectal
3.7
30.6
871
7105
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
+∞
30.4
29
*
L89
ICPC
Osteoarthrosis of hip
11.4
30.4
32
29
S18
ICPC
Laceration/cut
2.2
30.3
464
2886
ACC51
NOMESCO Finland
Release of median nerve
3.9
29.4
93
259
L08
ICPC
Shoulder symptom/complaint
2.4
28.8
242
1168
L13
ICPC
Hip symptom/complaint
2.7
28.7
177
736
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.6
28.6
41
56
N06AA09
ATC
amitriptyline; systemic
3.4
28.3
110
352
N02BF01
ATC
gabapentin; oral
3.2
28.2
121
411
M01AB05
ATC
diclofenac; systemic, rectal
2.2
27.5
639
4604
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
6.0
27.0
49
86
M19.9
ICD-10 Finland
Arthrosis, unspecified
6.3
26.9
46
76
M17.5
ICD-10 Finland
Other secondary gonarthrosis
77.5
26.9
30
*
M02AA07
ATC
piroxicam; topical
2.2
26.9
343
1964
M03BX02
ATC
tizanidine; oral
2.1
26.9
614
4377
NFF25
NOMESCO Finland
Cleaning of hip joint, arthroscopic
278.6
26.9
27
*
X58
ICD-10 Finland
Exposure to other specified factors
2.7
26.8
164
678
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.3
26.7
112
375
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.2
26.6
73
183
X59
ICD-10 Finland
Exposure to unspecified factor
2.5
26.4
197
897
1222
FHL
Arthroscopy and synovial surgery
+∞
26.2
25
*
NF1AA
NOMESCO Finland
Hip X-ray examination
4.2
26.0
72
182
M70.6
ICD-10 Finland
Trochanteric bursitis
3.0
25.9
130
483
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.0
25.8
76
201
H02AB06
ATC
prednisolone; systemic
2.1
25.8
449
2880
A07EC01
ATC
sulfasalazine; oral, rectal
5.2
25.6
54
109
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.8
25.5
81
226
9254
FHL
Arthrotomy (includes biopsy, revision, loose removal, fixation, and similar procedures)
51.5
25.4
30
6
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.7
25.1
158
661
B01AX06
ATC
[U] rivaroxaban
59.7
25.1
29
5
M01AX17
ATC
nimesulide; oral
2.3
24.9
235
1185
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
256.6
24.8
25
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
133.5
24.7
26
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
133.5
24.7
26
*
Z3226
NOMESCO Finland
Physiotherapist
2.5
24.3
176
788
L01BA01
ATC
methotrexate; systemic
30.0
24.2
32
11
A02BC02
ATC
pantoprazole; systemic
2.1
24.2
652
4852
M54.5
ICD-10 Finland
Low back pain
2.1
23.8
347
2070
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.5
23.5
85
259
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
8.6
23.2
30
36
N02AA05
ATC
oxycodone; systemic
2.4
23.2
190
898
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.5
23.2
83
251
N06AX21
ATC
duloxetine; oral
2.8
22.8
125
486
M19.2
ICD-10 Finland
Other secondary arthrosis
123.0
22.7
24
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
22.7
99
339
M01AB08
ATC
etodolac; oral
3.4
22.6
84
260
L17
ICPC
Foot/toe symptom/complaint
2.1
22.5
279
1563
R03AC02
ATC
salbutamol; inhalant
2.0
22.3
522
3650
M48.0
ICD-10 Finland
Spinal stenosis
2.8
22.3
120
462
M15
ICD-10 Finland
Polyarthrosis
5.2
22.3
47
95
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
21.8
350
2149
WX200
NOMESCO Finland
Interscalenous plexus blockade
7.3
21.7
32
45
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
21.5
118
459
M01AE02
ATC
naproxen; oral, rectal
1.9
21.5
515
3614
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.3
21.4
87
285
J01AA02
ATC
doxycycline; systemic
2.2
21.1
754
6054
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
4.1
20.8
58
147
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.5
20.8
76
233
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
3.8
20.6
66
185
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
20.6
368
2334
SPAT1153
SPAT
Removal of sutures
2.0
20.4
284
1650
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.1
20.4
57
145
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
20.2
337
2084
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
8.6
20.2
26
31
NG2AA
NOMESCO Finland
Patella X-ray examination
27.7
20.1
27
10
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
20.0
328
2015
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
+∞
19.9
19
*
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
5.0
19.8
43
89
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
75.1
19.8
22
*
A02BC05
ATC
esomeprazole; systemic
1.9
19.8
381
2469
NBB20
NOMESCO Finland
Primary total prosthetic replacement of humero-scapular joint
29.6
19.7
26
9
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
19.5
241
1337
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
32.0
19.3
25
8
L88
ICPC
Rheumatoid/seropositive arthritis
17.2
19.3
30
18
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
5.4
19.0
38
73
L40.5
ICD-10 Finland
Arthropathic psoriasis
56.2
19.0
22
*
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
18.8
18
*
71301
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) genus
+∞
18.8
18
*
NGT60
NOMESCO Finland
Forcible manipulation of knee joint
+∞
18.8
18
*
9243
FHL
Plastic of the patella and its tendons
28.5
18.8
25
9
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
71.4
18.8
21
*
NG1AA, ,
SPAT
3.0
18.6
85
298
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
3.7
18.6
60
169
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
18.4
291
1757
RF210, ,
NOMESCO Finland
6.8
18.4
29
44
M25.2
ICD-10 Finland
Flail joint
44.9
18.3
22
5
NG1DA
NOMESCO Finland
X-ray of knees
53.6
18.0
21
*
M01AE11
ATC
tiaprofenic acid; oral, rectal
4.6
17.9
43
97
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.5
17.8
62
184
L04AA13
ATC
[U] leflunomide
67.9
17.8
20
*
J01DB01
ATC
cefalexin; oral
2.1
17.8
767
6342
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
17.7
187
974
M54.4
ICD-10 Finland
Lumbago with sciatica
2.2
17.5
177
906
R4110
NOMESCO Finland
Physiotherapy
2.0
17.5
260
1534
L20
ICPC
Joint symptom/complaint NOS
5.0
17.4
38
79
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
5.0
17.4
38
79
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.0
17.4
78
271
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
17.3
110
459
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
17.8
17.0
26
15
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.4
16.8
63
196
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
64.5
16.8
19
*
SPAT1202
SPAT
Intra-articular injection
6.6
16.7
27
42
7180A
ICD-9 Finland
Other derangement of joint, Articular cartilage disorder[NIVELRUSTON SAIRAUS,OLKANIVEL]
+∞
16.7
16
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
16.7
16
*
9271
FHL
Hallux surgery
+∞
16.7
16
*
NGC20
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, normal prosthesis
+∞
16.7
16
*
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
16.7
180
944
L28
ICPC
Limited function/disability (L)
2.2
16.6
159
795
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
91.7
16.6
18
*
L12
ICPC
Hand/finger symptom/complaint
2.2
16.6
158
789
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
18.3
16.5
25
14
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.7
16.5
93
366
A02BC01
ATC
omeprazole; systemic
1.9
16.5
245
1442
S83.5
ICD-10 Finland
Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
4.3
16.4
42
100
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.9
16.3
48
127
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
21.4
16.0
23
11
NGE35
NOMESCO Finland
Plastic repair of ligament of knee not using prosthetic material, anterior cruciate, arthroscopic
5.6
15.8
30
55
M02AA10
ATC
ketoprofen; topical
2.2
15.8
150
748
72490, ,
ICD-8 Finland
+∞
15.7
15
*
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
5.7
15.6
29
52
NGF40
NOMESCO Finland
Repair of defect of cartilage in the knee joint with transplant
162.6
15.5
16
*
R4120
NOMESCO Finland
Occupational therapy
3.1
15.5
68
233
NBG10
NOMESCO Finland
Acromioplastia
5.9
15.5
28
49
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
15.3
173
922
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.9
15.3
34
72
L29
ICPC
Musculoskeletal sympt/complt other
2.7
15.3
85
332
L16
ICPC
Ankle symptom/complaint
2.5
15.2
106
462
M20.2
ICD-10 Finland
Hallux rigidus
18.1
15.2
23
13
S43.0
ICD-10 Finland
Dislocation of shoulder joint
3.8
15.2
46
124
72908
ICD-8 Finland
Other diseases of joint, Alii definiti
23.8
15.1
21
9
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
45.8
15.1
18
*
D07AC01
ATC
betamethasone; topical
1.8
15.1
335
2225
1224
FHL
Arthroscopy and loose removal
57.6
14.8
17
*
R03DC03
ATC
montelukast; oral
2.1
14.7
156
811
J01DA01
ATC
[U] cefalexin
1.7
14.7
560
4315
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
14.6
652
5244
212
Kela drug reimbursment
Gout
+∞
14.6
14
*
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
14.6
14
*
NBL22
NOMESCO Finland
Myotomy, tenotomy or excision of tendon of upper arm
6.5
14.6
24
38
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
81.4
14.6
16
*
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
4.8
14.6
33
71
M01AH02
ATC
rofecoxib; oral
2.4
14.3
101
442
M24.2
ICD-10 Finland
Disorder of ligament
27.6
14.3
19
7
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
10.7
14.3
27
26
Z50.1
ICD-10 Finland
Other physical therapy
3.3
14.1
53
165
M04AA01
ATC
allopurinol; systemic
2.4
13.8
105
475
G47.3
ICD-10 Finland
Sleep apnoea
1.9
13.8
223
1338
M93.2
ICD-10 Finland
Osteochondritis dissecans
54.2
13.8
16
*
M19.8
ICD-10 Finland
Other specified arthrosis
4.2
13.8
37
91
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.0
13.8
63
221
A01
ICPC
Pain general/multiple sites
2.5
13.8
93
399
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
13.8
200
1160
S80.0
ICD-10 Finland
Contusion of knee
2.7
13.6
74
285
WZA00
NOMESCO Finland
Concise certificate
3.2
13.6
54
174
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
76.3
13.6
15
*
M23.4
ICD-10 Finland
Loose body in knee
+∞
13.6
13
*
M22.0
ICD-10 Finland
Recurrent dislocation of patella
+∞
13.6
13
*
7350A
ICD-9 Finland
Acquired deformities of toe, Hallux valgus (acquired)
+∞
13.6
13
*
9241
FHL
Due to repeated dislocation of the shoulder joint plastic
+∞
13.6
13
*
NGC60
NOMESCO Finland
Exchange or addition of patellar part
+∞
13.6
13
*
7174A
ICD-9 Finland
Internal derangement of knee, Derangement of lateral meniscus
+∞
13.6
13
*
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
+∞
13.6
13
*
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
16.5
13.5
21
13
M25.0
ICD-10 Finland
Haemarthrosis
142.0
13.5
14
*
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
18.5
13.4
20
11
WZA90
NOMESCO Finland
Other medical or dental certificate
1.9
13.3
199
1164
M10.0
ICD-10 Finland
Idiopathic gout
5.4
13.3
26
49
M01AB55
ATC
diclofenac, combinations; oral
3.1
13.2
56
188
H02AB04
ATC
methylprednisolone; systemic
2.1
13.2
129
648
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.6
13.1
31
69
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
15.3
13.1
21
14
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.2
13.1
53
173
TQW40
NOMESCO Finland
Remowal of suture of skin
2.8
13.1
68
256
M79.1
ICD-10 Finland
Myalgia
2.1
13.1
134
686
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.3
12.9
49
154
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
3.4
12.9
46
139
M77.1
ICD-10 Finland
Lateral epicondylitis
2.6
12.9
80
330
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
50.7
12.9
15
*
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.2
12.8
51
165
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
10.7
12.8
24
23
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
10.7
12.8
24
23
R06AE07
ATC
cetirizine; oral
1.7
12.7
371
2629
M35.7
ICD-10 Finland
Hypermobility syndrome
15.7
12.6
20
13
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
12.6
277
1816
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
70.8
12.6
14
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
10.2
12.5
24
24
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
12.5
12
*
NGC30
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, special prosthesis
+∞
12.5
12
*
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
13.4
12.5
21
16
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
131.7
12.5
13
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
131.7
12.5
13
*
WX002
NOMESCO Finland
Sedation and analgesia
2.0
12.4
153
837
J04AB02
ATC
rifampicin; systemic
11.8
12.4
22
19
M54.3
ICD-10 Finland
Sciatica
2.8
12.2
61
225
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
12.2
425
3144
R06.0
ICD-10 Finland
Dyspnoea
1.8
12.0
235
1490
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
11.9
201
1217
N02BF02
ATC
pregabalin; oral
2.7
11.9
63
240
M79.7
ICD-10 Finland
Fibromyalgia
4.2
11.9
31
75
R20.2
ICD-10 Finland
Paraesthesia of skin
2.6
11.8
69
276
S70.0
ICD-10 Finland
Contusion of hip
3.5
11.8
41
122
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
11.7
203
1239
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
5.6
11.7
22
40
R05
ICD-10 Finland
Cough
1.8
11.7
189
1130
WZC30
NOMESCO Finland
Teaching
1.9
11.6
166
954
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
3.1
11.6
48
159
A02BC03
ATC
lansoprazole; oral
1.7
11.6
251
1634
L04AB01
ATC
etanercept; parenteral
23.2
11.6
16
7
M77.4
ICD-10 Finland
Metatarsalgia
2.9
11.6
54
192
J01FA10
ATC
azithromycin; systemic
1.6
11.5
499
3871
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
11.5
315
2182
7152F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,POLVI]
+∞
11.5
11
*
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
+∞
11.5
11
*
M22.1
ICD-10 Finland
Recurrent subluxation of patella
121.4
11.4
12
*
R01AD01
ATC
beclometasone; nasal
2.0
11.4
146
809
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
4.3
11.3
29
69
A02BA02
ATC
ranitidine; systemic
1.9
11.3
173
1015
R01AD09
ATC
mometasone; nasal
1.6
11.3
387
2835
RD211, ,
NOMESCO Finland
3.1
11.3
48
162
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
11.2
565
4532
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
11.2
122
637
R03AC03
ATC
terbutaline; inhalant
2.1
11.2
121
630
NF1DA
NOMESCO Finland
X-ray of hips
17.3
11.2
17
10
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
5.6
11.2
21
38
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
11.2
409
3040
ZXD20
NOMESCO Finland
Day surgery
2.1
11.0
106
529
M01AE01
ATC
ibuprofen; systemic, rectal
1.9
11.0
823
7311
J01FA06
ATC
roxithromycin; oral
1.6
11.0
348
2497
TNG10
NOMESCO Finland
Puncture of knee
43.8
10.9
13
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
10.9
174
1034
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
10.9
79
350
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.9
10.9
50
176
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
5.2
10.8
22
43
M03BC51
ATC
orphenadrine, combinations; systemic
1.7
10.8
233
1513
9255
FHL
Joint auger removal
28.4
10.7
14
5
M77.0
ICD-10 Finland
Medial epicondylitis
4.1
10.7
29
72
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.5
10.7
67
277
72221
ICD-8 Finland
Osteochondrosis, Dissecans
60.7
10.6
12
*
M24.8
ICD-10 Finland
Other specific joint derangements, not elsewhere classified
60.7
10.6
12
*
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.1
10.6
43
141
M15.8
ICD-10 Finland
Other polyarthrosis
9.3
10.5
21
23
NH1AD
NOMESCO Finland
Ankle and foot CT
4.7
10.5
24
52
R03AK07
ATC
formoterol and budesonide; inhalant
1.8
10.5
197
1228
J01FF01
ATC
clindamycin; systemic
1.7
10.4
232
1516
M17.2
ICD-10 Finland
Post-traumatic gonarthrosis, bilateral
111.2
10.4
11
*
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
111.2
10.4
11
*
NGC99
NOMESCO Finland
Other secondary prosthetic replacement inknee joint, other or unspecified
+∞
10.4
10
*
NGC00
NOMESCO Finland
Exchange of a loose part of prosthesis in knee joint
+∞
10.4
10
*
7180G
ICD-9 Finland
Other derangement of joint, Articular cartilage disorder[NIVELRUSTON SAIRAUS,NILKKA]
+∞
10.4
10
*
73799
ICD-8 Finland
Hallux valgus and varus
+∞
10.4
10
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
10.4
10
*
R60.0
ICD-10 Finland
Localized oedema
2.1
10.4
100
498
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
5.2
10.3
21
41
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
10.3
456
3524
XA402
NOMESCO Finland
ENMG
4.1
10.3
28
70
H02AB07
ATC
prednisone; oral
2.1
10.3
107
550
Z01.2
ICD-10 Finland
Dental examination
1.6
10.3
382
2836
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.2
10.2
92
447
M01AH03
ATC
valdecoxib; oral
2.7
10.1
56
218
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
10.1
195
1224
Z71.8
ICD-10 Finland
Other specified counselling
1.6
10.1
283
1962
L03
ICPC
Low back symptom/complaint
1.7
10.1
230
1512
S83.3
ICD-10 Finland
Tear of articular cartilage of knee, current
11.4
10.1
18
16
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.8
10.0
51
190
EC1VA, ,
NOMESCO Finland
2.9
9.9
47
169
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
9.9
185
1151
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
5.2
9.9
20
39
ZXE00
NOMESCO Finland
One hour or less
1.6
9.9
312
2225
S83.4
ICD-10 Finland
Sprain and strain involving (fibular)(tibial) collateral ligament of knee
3.9
9.8
29
77
S83.0
ICD-10 Finland
Dislocation of patella
10.8
9.8
18
17
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
7.5
9.7
22
30
Z3231
NOMESCO Finland
Registered nurse
1.7
9.6
234
1562
M54.2
ICD-10 Finland
Cervicalgia
2.3
9.6
71
318
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
15.2
9.5
15
10
M23.3
ICD-10 Finland
Other meniscus derangements
15.2
9.5
15
10
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.0
9.5
107
565
R50.9
ICD-10 Finland
Fever, unspecified
1.9
9.5
134
764
R52.9
ICD-10 Finland
Pain, unspecified
2.1
9.5
88
432
M01CB01
ATC
sodium aurothiomalate; parenteral
101.0
9.4
10
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
9.4
629
5283
NHG20
NOMESCO Finland
Fusion of talocrural joint
+∞
9.4
9
*
72904
ICD-8 Finland
Other diseases of joint, Dislocatio spontanea
+∞
9.4
9
*
NGB10
NOMESCO Finland
Primary partial prosthetic replacement of knee joint, demi prosthesis
+∞
9.4
9
*
7188E
ICD-9 Finland
Other derangement of joint, Other joint derangement, not elsewhere classified[MB ARTICULI, LIGAM ET CARTILAG AL DEF,LONKKANIVEL]
+∞
9.4
9
*
7183A
ICD-9 Finland
Other derangement of joint, Recurrent dislocation of joint[LUXATIO HABITUALIS, OLKANIVEL]
+∞
9.4
9
*
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
9.3
123
686
M01AB16
ATC
aceclofenac; oral
3.7
9.3
29
80
N04BC05
ATC
pramipexole; oral
2.3
9.3
73
335
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.3
9.3
71
322
N06AX16
ATC
venlafaxine; oral
1.9
9.3
123
688
S89.9
ICD-10 Finland
Unspecified injury of lower leg
3.5
9.3
31
90
H02BX01
ATC
methylprednisolone, combinations; systemic
2.9
9.2
43
153
TQW40, ,
SPAT
2.1
9.2
89
445
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
3.0
9.2
40
137
L14
ICPC
Leg/thigh symptom/complaint
2.3
9.2
69
311
NG1AD
NOMESCO Finland
Knee CT examination
7.8
9.2
20
26
R96
ICPC
Asthma
2.1
9.2
84
411
SFA10
NOMESCO Finland
One-surface restoration
1.5
9.1
471
3730
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.3
9.1
33
101
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
4.6
9.1
21
46
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
4.8
9.1
20
42
AA1AD
NOMESCO Finland
CT of head and brain
1.6
9.1
258
1788
T93.3
ICD-10 Finland
Sequelae of dislocation, sprain and strain of lower limb
15.8
9.0
14
9
R05
ICPC
Cough
1.7
9.0
209
1375
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.6
9.0
29
82
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.7
9.0
47
178
M01AC01
ATC
piroxicam; systemic, rectal
1.9
9.0
111
606
R52.2
ICD-10 Finland
Other chronic pain
3.3
9.0
34
107
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
24.3
8.9
12
5
UJF32
NOMESCO Finland
Coloscopy
1.6
8.9
219
1464
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.6
8.8
29
83
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
10.8
8.8
16
15
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.6
8.8
49
192
P06
ICPC
Sleep disturbance
2.0
8.8
106
574
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
8.8
241
1654
L91
ICPC
Osteoarthrosis other
7.3
8.8
20
28
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
8.7
83
412
R5110, ,
SPAT
2.3
8.7
69
318
M01AB01
ATC
indometacin; systemic, rectal
2.3
8.7
67
305
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.3
8.7
33
104
ZX140
NOMESCO Finland
Intra articular
50.5
8.7
10
*
M96.0
ICD-10 Finland
Pseudarthrosis after fusion or arthrodesis
50.5
8.7
10
*
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
50.5
8.7
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
8.7
118
665
RF410, ,
NOMESCO Finland
11.7
8.6
15
13
M65.3
ICD-10 Finland
Trigger finger
2.7
8.6
44
165
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.6
8.6
28
80
9244
FHL
Plastic or reconstruction of ligaments of the knee other than the lumbar region
16.5
8.6
13
8
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
8.5
82
409
G44.2
ICD-10 Finland
Tension-type headache
1.9
8.4
110
611
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.3
8.4
31
96
M01AE51
ATC
ibuprofen, combinations; systemic
4.9
8.4
18
37
NHG22
NOMESCO Finland
Fusion of subtalar joint
+∞
8.3
8
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
8.3
126
734
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
8.3
93
490
RF420, ,
NOMESCO Finland
9.6
8.3
16
17
R52.1
ICD-10 Finland
Chronic intractable pain
9.6
8.3
16
17
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
9.6
8.3
16
17
N02AC04
ATC
dextropropoxyphene; oral
3.0
8.3
35
118
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.8
8.3
42
157
B01AB04
ATC
dalteparin; parenteral
2.8
8.2
41
152
S83
ICD-10 Finland
Dislocation, sprain and strain of joints and ligaments of knee
4.6
8.1
19
42
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
3.5
8.1
27
78
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.3
8.1
58
256
NCF25
NOMESCO Finland
Operation for osteochondritis of elbow joint, arthroscopic
33.6
8.1
10
*
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
11.8
8.1
14
12
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
17.3
8.1
12
7
R03BA05
ATC
fluticasone; inhalant
1.7
8.1
152
944
J01FA09
ATC
clarithromycin; systemic
1.6
8.0
262
1866
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
22.2
8.0
11
5
N06AX11
ATC
mirtazapine; oral
1.5
8.0
289
2105
M01AX01
ATC
nabumetone; oral
3.0
8.0
34
115
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
7.9
246
1732
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
7.9
206
1391
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.9
188
1241
SFA20
NOMESCO Finland
Two-surface restoration
1.5
7.9
501
4090
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
7.9
206
1392
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
4.7
7.9
18
39
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.3
7.9
62
285
9057A
ICD-9 Finland
Late effects of musculoskeletal and connective tissue injuries, Late effect of sprain and strain without mention of tendon injury
13.2
7.9
13
10
NB1AD
NOMESCO Finland
Shoulder CT examination
6.2
7.9
20
33
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
7.9
148
919
S66.3
ICD-10 Finland
Injury of extensor muscle and tendon of other finger at wrist and hand level
3.8
7.8
23
61
84500
ICD-8 Finland
Sprains and strains of ankle and foot, Ankle
4.1
7.8
21
52
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.9
7.8
94
508
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.8
209
1422
A03
ICPC
Fever
1.7
7.8
140
858
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
3.7
7.8
24
66
WX290
NOMESCO Finland
Other blockage of nerve
1.5
7.8
391
3048
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
7.7
98
539
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
15.2
7.7
12
8
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.3
7.7
29
91
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.7
330
2489
M54.6
ICD-10 Finland
Pain in thoracic spine
2.2
7.7
65
308
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.6
7.7
18
40
J01CA04
ATC
amoxicillin; systemic
1.5
7.6
713
6274
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.3
7.6
60
276
8449X
ICD-9 Finland
Sprains and strains of knee and leg, Unspecified site of knee and leg
18.5
7.6
11
6
XQ902
NOMESCO Finland
Other photography
8.9
7.6
15
17
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
2.9
7.5
34
119
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
7.5
239
1691
R51.80
ICD-10 Finland
Headache
1.8
7.5
122
727
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
7.5
69
339
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
3.6
7.5
24
68
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.2
7.4
28
88
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.5
7.4
25
73
NGE15
NOMESCO Finland
Incision fo capsule of knee joint, arthroscopic
80.7
7.4
8
*
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
80.7
7.4
8
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
7.4
212
1463
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.9
7.4
102
577
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
7.3
147
928
A29
ICPC
General symptom/complaint other
1.8
7.3
114
670
7180E
ICD-9 Finland
Other derangement of joint, Articular cartilage disorder[NIVELRUSTON SAIRAUS,LONKKANIVEL]
+∞
7.3
7
*
NGF30
NOMESCO Finland
Fixation of loose body of joint of knee
+∞
7.3
7
*
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
+∞
7.3
7
*
K02.1
ICD-10 Finland
Caries of dentine
1.5
7.3
490
4022
R07.0
ICD-10 Finland
Pain in throat
2.3
7.3
55
249
ZXA10
NOMESCO Finland
Bilateral
1.7
7.3
143
898
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
5.9
7.2
19
33
L04AB06
ATC
golimumab; parenteral
15.9
7.2
11
7
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.2
132
814
L10
ICPC
Elbow symptom/complaint
2.4
7.2
48
206
9056A
ICD-9 Finland
Late effects of musculoskeletal and connective tissue injuries, Late effect of dislocation
30.3
7.2
9
*
NDG76
NOMESCO Finland
Fusion of DIP joint
30.3
7.2
9
*
R01AD12
ATC
fluticasone furoate; nasal
1.5
7.1
252
1821
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
7.1
109
637
SPAT1229
SPAT
Assessment of need for aid
2.3
7.1
53
239
B01AF02
ATC
apixaban; oral
1.8
7.1
113
669
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
7.1
106
616
K03.66
ICD-10 Finland
Tooth plaque
2.1
7.0
67
333
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
7.0
54
246
QDB10, ,
SPAT
3.2
7.0
27
86
TKC22
NOMESCO Finland
Catheterisation instruction
3.5
7.0
23
66
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
7.1
7.0
16
23
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
3.3
7.0
26
81
J02AC01
ATC
fluconazole; systemic
1.5
7.0
298
2236
A46
ICD-10 Finland
Erysipelas
1.8
7.0
117
702
N02AJ13
ATC
tramadol and paracetamol; systemic
3.7
6.9
21
57
L11
ICPC
Wrist symptom/complaint
2.0
6.9
71
363
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
6.9
121
736
C07AB07
ATC
bisoprolol; oral
1.4
6.9
420
3376
S15
ICPC
Foreign body in skin
2.2
6.8
54
249
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
4.2
6.8
18
44
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.8
6.8
16
24
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
6.8
55
256
R03BA02
ATC
budesonide; inhalant
1.7
6.8
145
929
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.1
6.8
28
93
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
6.8
460
3763
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
40.3
6.8
8
*
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
40.3
6.8
8
*
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
40.3
6.8
8
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
16.8
6.8
10
6
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.1
6.7
61
298
E0000UV, ,
ATC
1.5
6.7
331
2553
NGH20
NOMESCO Finland
Reduction of dislocation of knee joint, open
22.7
6.7
9
*
S50.0
ICD-10 Finland
Contusion of elbow
2.9
6.7
30
105
NF1AA, ,
SPAT
2.5
6.7
40
163
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.7
226
1616
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.0
6.6
75
398
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
6.6
213
1507
N06AX03
ATC
mianserin; oral
2.4
6.6
44
189
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
8.8
6.6
13
15
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.7
6.6
33
123
M43.1
ICD-10 Finland
Spondylolisthesis
2.7
6.6
33
123
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.8
6.6
97
561
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
3.9
6.6
19
50
L01
ICPC
Neck symptom/complaint
1.7
6.5
121
748
C03CA01
ATC
furosemide; systemic
1.5
6.5
224
1607
M75.2
ICD-10 Finland
Bicipital tendinitis
3.4
6.4
22
65
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.2
6.4
53
249
NDG30
NOMESCO Finland
Fusion of wrist, total
70.3
6.4
7
*
NHE20
NOMESCO Finland
Plastic repair of capsule or ligament of ankle joint with transplant
70.3
6.4
7
*
NBC40
NOMESCO Finland
Secondary implantation of prosthesis in humeroscapular joint, both parts
70.3
6.4
7
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.8
6.4
31
113
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
14.4
6.4
10
7
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.3
6.4
46
204
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.5
6.4
267
1990
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
6.4
209
1481
J01EA01
ATC
trimethoprim; systemic
1.5
6.4
191
1327
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
6.4
307
2352
EB1VA, ,
NOMESCO Finland
1.6
6.4
143
929
205
Kela drug reimbursment
Chronic hypertension
1.5
6.3
210
1492
R5599
NOMESCO Finland
Other rehabilitation service
3.1
6.3
25
81
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
6.3
378
3011
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.6
6.3
35
137
8442A
ICD-9 Finland
Sprains and strains of knee and leg, Cruciate ligament of knee[DISTORSIO/DISTEN/RUPT.LIG.CRUCIATI ANTERIORIS GENUS]
8.2
6.3
13
16
WX702
NOMESCO Finland
Supraglottic ventilation device
2.3
6.3
48
218
L04AB04
ATC
adalimumab; parenteral
6.0
6.3
16
27
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
6.3
51
238
R4110, ,
SPAT
1.8
6.3
100
591
R09
ICPC
Sinus symptom/complaint
2.1
6.3
61
306
J01XX08
ATC
linezolid; systemic
18.2
6.3
9
5
D01AC02
ATC
miconazole; topical
2.0
6.3
65
334
C10AA05
ATC
atorvastatin; oral
1.4
6.3
369
2932
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
+∞
6.3
6
*
349
Kela drug reimbursment
Febuxostat
+∞
6.3
6
*
7183F
ICD-9 Finland
Other derangement of joint, Recurrent dislocation of joint[LUXATIO HABITUALIS, POLVI]
+∞
6.3
6
*
7176A
ICD-9 Finland
Internal derangement of knee, Loose body in knee
+∞
6.3
6
*
M24.0
ICD-10 Finland
Loose body in joint
+∞
6.3
6
*
NGF10
NOMESCO Finland
Total synovectomy of knee, open
+∞
6.3
6
*
71309
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) NUD
+∞
6.3
6
*
L04AC07
ATC
tocilizumab; parenteral
+∞
6.3
6
*
J01DA09
ATC
[U] cefadroxil
1.5
6.3
214
1531
M23.5
ICD-10 Finland
Chronic instability of knee
26.9
6.2
8
*
NBB10
NOMESCO Finland
Primary partial prosthetic replacement of humero-scapular joint not using cement, other or unspecified
26.9
6.2
8
*
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
26.9
6.2
8
*
M25.4
ICD-10 Finland
Effusion of joint
7.1
6.2
14
20
Y88.1
ICD-10 Finland
Sequelae of misadventures to patients during surgical and medical procedures
7.1
6.2
14
20
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.8
6.2
92
532
R05FB02
ATC
cough suppressants and expectorants; systemic
1.4
6.2
299
2289
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
5.1
6.2
18
36
J46
ICD-10 Finland
Status asthmaticus
3.2
6.2
24
77
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
6.2
360
2853
WX204
NOMESCO Finland
Axillary plexus blockaced
2.8
6.2
30
110
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.1
304
2338
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
6.1
57
281
RF220, ,
NOMESCO Finland
7.7
6.1
13
17
E66.01
ICD-10 Finland
Obesity due to excess calories
2.0
6.1
67
351
R06AX27
ATC
desloratadine; oral
1.5
6.1
221
1598
T90
ICPC
Diabetes non-insulin dependent
1.5
6.1
212
1520
NBL05
NOMESCO Finland
Arthroscopic suture or reinsertation of rotator cuff of shoulder
3.8
6.1
18
48
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
4.2
6.1
16
39
M01AC02
ATC
tenoxicam; systemic, rectal
2.5
6.1
37
152
92700
ICD-8 Finland
Contusion of hip, thigh, leg and ankle, Current injury
8.7
6.1
12
14
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
3.6
6.1
19
53
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
10.1
6.0
11
11
L84
ICD-10 Finland
Corns and callosities
2.9
6.0
28
100
M23
ICD-10 Finland
Internal derangement of knee
3.4
6.0
21
63
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.3
6.0
46
210

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
36
20
18.67
44.87
1.8
1.1
—
—
—
0
0
47
43
11.45
44.49
1.7
1.1
11297.85
12308.19
e6/l
0.06
33
31
223
924
2.85
37.18
1.3
1.1
3.41
1.54
u/ml
0.60
97
368
238
1038
2.73
35.83
1.4
1.2
25.80
17.91
iu/ml
0.86
65
272
37
34
11.28
34.83
1.5
1.0
—
—
—
0
0
192
980
2.20
19.29
2.3
2.0
—
—
—
0
0
301
1824
1.95
18.94
2.9
2.6
340.37
346.97
umol/l
0.56
267
1630
476
3384
1.81
17.80
3.1
2.7
—
—
estimate
—
0
0
161
810
2.19
16.59
1.3
1.3
387.32
466.09
titre
0.37
41
161
25
16
16.01
15.77
1.6
1.0
55.57
73.22
%
—
14
9
271
1671
1.87
15.69
1.8
1.7
0.97
1.33
mg/l
2.38
223
1295
515
3839
1.75
15.59
6.2
5.6
0.04
0.04
e9/l
0.66
449
3253
513
3838
1.73
15.16
6.2
5.6
0.58
0.58
e9/l
0.05
450
3250
520
3916
1.72
14.91
6.3
5.6
1.89
1.91
e9/l
0.10
461
3395
524
3977
1.71
14.40
6.4
5.9
0.20
0.19
e9/l
0.58
464
3424
724
6037
1.84
14.04
8.7
8.2
78.03
79.75
u/l
0.63
702
5743
64
229
2.92
13.52
1.3
1.9
2.46
7.89
iu/ml
1.70
17
60
342
2378
1.68
12.56
2.2
2.2
251.65
241.09
u/l
0.06
331
2255
357
2512
1.67
12.53
3.0
2.8
59.33
64.56
u/l
0.38
337
2333
262
1716
1.73
11.89
3.0
2.5
5.21
5.89
e6/l
0.28
245
1549
520
4059
1.62
11.84
4.6
3.4
0.00
5.61
estimate
1.07
111
823
389
2830
1.63
11.80
4.3
3.7
51.32
132.86
e6/l
1.91
305
1998
474
3623
1.62
11.72
14.2
13.8
1.24
1.24
inr
0.07
392
3029
521
4077
1.62
11.67
4.6
3.4
0.03
0.02
estimate
0.13
106
759
860
7727
2.19
11.63
19.5
14.5
23.72
27.28
mg/l
2.17
752
6151
584
4703
1.63
11.59
4.9
5.6
6.74
6.76
mmol/l
0.11
568
4470
353
2518
1.64
11.51
3.8
3.1
44.21
59.09
e6/l
0.34
292
1899
513
4014
1.60
11.38
4.5
3.4
0.00
0.00
estimate
0.50
108
822
460
3513
1.60
11.26
5.3
5.5
36.03
35.70
g/l
0.66
440
3312
603
4942
1.60
10.71
5.2
4.1
3.33
965.66
e6/l
—
6
68
148
840
1.90
10.71
2.6
3.8
4.64
5.96
e9/l
0.79
131
734
44
147
3.09
10.50
1.1
1.1
—
—
—
0
0
306
2169
1.61
9.93
3.5
3.0
0.21
0.53
e6/l
4.52
248
1570
530
4261
1.55
9.86
5.8
7.5
11.02
12.00
umol/l
0.77
512
4071
490
3905
1.53
9.25
7.4
7.9
1.21
1.21
mmol/l
0.52
440
3368
56
231
2.51
9.04
1.2
1.2
0.36
0.90
u/ml
—
9
14
414
3194
1.52
9.03
3.6
3.1
6.24
6.22
ph
0.15
231
1826
305
2206
1.56
8.90
4.5
4.4
—
—
—
0
0
448
3530
1.51
8.75
6.4
5.7
56.96
57.42
%
0.35
430
3389
446
3514
1.51
8.70
6.4
5.8
2.84
2.82
%
0.11
420
3311
445
3511
1.50
8.58
6.6
5.8
0.66
0.67
%
0.19
419
3299
539
4442
1.49
8.28
8.9
9.8
4.10
4.11
e9/l
0.02
483
3833
315
2326
1.53
8.25
4.2
4.1
7.40
7.40
ph
0.07
224
1631
441
3495
1.49
8.20
6.4
7.2
1.21
1.21
mmol/l
0.70
420
3212
393
3048
1.49
8.10
4.2
3.6
32.75
57.89
ng/l
1.23
292
2158
439
3482
1.48
8.09
11.7
10.5
0.00
0.00
e9/l
0.43
373
2809
659
5676
1.53
8.05
4.1
3.9
—
11224.33
—
0
9
271
1945
1.55
8.04
2.5
2.1
2.95
2.76
mg/l
0.54
241
1627
110
621
1.87
8.03
2.7
2.3
0.53
0.59
e6/l
0.09
105
593
452
3610
1.48
8.02
6.4
5.8
28.05
27.52
%
0.47
427
3444
441
3523
1.47
7.72
6.6
5.9
8.90
8.98
%
0.23
416
3315
297
2195
1.51
7.63
5.1
3.4
0.00
0.01
estimate
1.34
105
748
331
2505
1.49
7.57
6.1
5.7
—
—
—
0
0
430
3434
1.46
7.46
2.6
2.3
74.96
76.48
nmol/l
0.58
404
3106
347
2667
1.47
7.29
3.5
3.4
87.05
50.09
mg/l
0.38
246
1705
195
1327
1.59
7.21
3.1
2.8
1.06
0.99
e6/l
0.11
123
689
359
2798
1.46
6.93
3.8
3.3
7.48
7.81
mmol/l
0.69
324
2403
350
2715
1.46
6.93
4.3
4.0
17.82
9.23
mg/mmol
0.39
238
1709
872
8123
1.90
6.90
21.7
17.8
139.58
139.74
mmol/l
1.10
867
7934
387
3067
1.44
6.80
4.5
3.4
0.00
0.07
estimate
1.14
92
663
872
8141
1.87
6.59
22.1
18.0
4.00
3.98
mmol/l
1.27
866
7939
432
3517
1.42
6.44
3.5
2.8
125.98
147.66
ug/l
1.26
413
3278
107
641
1.75
6.43
2.8
2.0
0.00
0.04
estimate
0.78
17
125
292
2214
1.46
6.41
3.8
3.0
—
—
—
0
0
315
2424
1.45
6.40
2.8
2.4
—
—
—
0
0
133
848
1.66
6.36
1.8
1.7
—
—
—
0
0
236
1720
1.50
6.31
4.8
4.5
—
—
—
0
0
291
2219
1.45
6.16
1.7
1.7
20.77
19.98
nmol/l
0.38
262
1886
424
3465
1.40
6.07
2.1
2.0
94.74
94.19
pmol/l
0.09
251
1894
32
123
2.66
6.02
1.1
1.2
39.24
53.12
u/ml
—
5
16
677
6013
1.44
5.89
4.8
4.1
14.78
14.77
pmol/l
0.03
637
5516
867
8125
1.77
5.84
17.3
13.1
—
—
—
0
0
817
7547
1.59
5.75
7.3
6.1
40.35
39.43
mmol/mol
1.91
782
7037
81
462
1.82
5.74
2.6
2.5
32.43
18.91
au/ml
—
10
49
101
623
1.70
5.47
4.4
4.7
0.04
0.16
%
1.08
25
175
75
425
1.83
5.44
1.3
1.3
64.40
59.37
au/ml
—
5
32
268
2057
1.42
5.36
4.1
4.1
93.00
89.28
%
1.71
261
2012
296
2321
1.40
5.22
7.5
6.3
—
—
—
0
0
725
6576
1.43
5.18
22.2
18.4
13.71
13.60
%
1.43
718
6473
234
1771
1.43
5.02
5.1
3.4
1.02
1.90
kg/l
0.50
160
1139
57
308
1.90
4.81
2.1
1.9
—
—
—
0
0
197
1458
1.44
4.75
1.4
1.5
2.29
2.50
g/l
0.97
131
903
784
7253
1.46
4.71
5.9
5.0
1.84
1.95
mu/l
1.79
749
6687
10
14
7.21
4.66
1.4
1.0
—
—
—
0
0
238
1829
1.40
4.64
2.7
2.4
—
—
—
0
0
135
933
1.52
4.58
1.5
1.6
—
—
—
0
0
57
320
1.83
4.30
2.8
2.2
0.00
0.01
estimate
0.50
15
100
198
1494
1.41
4.26
3.4
2.8
530.19
530.98
mosm/kgh2o
0.02
179
1294
151
1086
1.46
4.21
6.2
6.1
1.06
1.03
mmol/l
0.41
143
1004
50
271
1.89
4.21
9.4
9.6
—
—
—
0
0
132
925
1.50
4.19
1.4
1.5
—
—
—
0
0
328
2691
1.33
4.17
2.8
3.3
29.91
33.77
u/l
1.96
298
2554
19
68
2.83
4.14
1.4
1.5
—
—
—
0
0
79
497
1.64
4.01
3.3
3.6
7.41
7.42
ph
0.21
66
424
62
367
1.74
3.94
1.3
1.2
—
—
—
0
0
30
139
2.20
3.86
2.4
2.1
273.26
7107.83
u/l
—
9
55
217
1690
1.37
3.84
1.3
1.3
1.63
1.97
u/ml
0.21
60
458
124
876
1.48
3.79
5.9
10.4
95.14
95.63
%
0.27
119
850
35
175
2.04
3.73
1.2
1.4
285.89
651.23
e6/l
0.35
27
133
280
2285
1.32
3.60
3.1
3.1
1008.35
1244.71
ng/l
0.58
245
1970
603
5447
1.29
3.53
3.7
3.3
48.84
51.64
u/l
0.40
578
5139
92
620
1.54
3.52
4.4
4.5
0.09
0.13
%
0.32
23
190
93
629
1.53
3.50
4.1
4.3
0.84
0.81
%
0.04
28
211
96
654
1.52
3.50
4.3
4.4
1.30
1.06
%
0.32
27
223
34
174
1.99
3.42
1.2
1.3
2.44
8.61
e6/l
0.87
25
130
164
1244
1.38
3.39
3.4
2.9
1.76
1.87
e6/l
0.09
92
600
58
353
1.68
3.37
2.5
2.3
—
—
—
0
0
124
899
1.44
3.32
2.0
2.4
241.50
153.87
ug/g
0.60
93
728
108
768
1.46
3.21
2.7
2.3
12.74
13.34
nmol/l
0.41
101
699
12
34
3.56
3.20
1.2
1.0
—
—
—
0
0
13
45
2.92
3.03
1.2
1.2
32.23
28.87
umol/l
0.39
13
40
13
45
2.92
3.03
1.2
1.2
147.23
142.88
nmol/l
0.08
13
45
25
120
2.11
3.00
2.1
2.1
0.88
0.92
g/l
0.06
19
95
30
156
1.95
2.92
1.1
1.4
—
—
—
0
0
55
344
1.64
2.92
3.1
3.7
—
—
—
0
0
324
2759
1.26
2.90
3.4
4.1
2.36
2.36
mmol/l
0.02
310
2531
199
1594
1.31
2.87
3.7
3.7
133.42
530.20
ng/l
3.75
153
1240
104
755
1.42
2.78
1.5
1.6
—
—
—
0
0
71
479
1.52
2.75
1.9
2.8
—
—
—
0
0
84
588
1.47
2.73
3.8
3.7
114.12
92.77
ng/l
0.46
76
510
199
1607
1.30
2.70
2.9
3.3
2.45
2.45
mmol/l
0.01
188
1468
72
490
1.51
2.68
1.4
1.6
—
—
—
0
0
22
106
2.10
2.64
1.3
1.2
—
—
—
0
0
50
317
1.61
2.54
1.2
1.4
—
7.83
—
0
8
81
572
1.45
2.53
1.2
1.2
—
—
—
0
0
87
624
1.43
2.50
3.3
3.5
1.23
1.23
mmol/l
0.13
74
524
49
311
1.61
2.49
2.7
2.7
—
—
—
0
0
72
500
1.48
2.45
3.2
5.7
—
—
—
0
0
128
985
1.35
2.43
6.1
10.0
7.42
7.41
ph
0.72
73
546
22
110
2.02
2.42
2.5
2.4
—
—
—
0
0
8
22
3.66
2.36
3.9
9.5
29.88
25.56
mmol/l
—
8
22
12
46
2.63
2.36
1.2
1.2
—
—
—
0
0
34
200
1.73
2.31
1.4
1.4
7.86
9.22
u/l
0.32
26
160
259
2199
1.24
2.31
4.1
3.0
0.01
0.01
estimate
0.02
94
627
18
85
2.14
2.30
2.0
1.2
1.90
1.62
nmol/l
0.29
18
80
78
558
1.43
2.29
4.7
2.4
6.20
6.05
ph
0.76
58
375
32
186
1.75
2.27
2.1
2.2
128.15
127.78
g/l
0.03
26
145
19
93
2.06
2.22
1.1
1.5
14.33
24.95
ng/l
1.56
19
93
42
266
1.61
2.18
1.1
1.2
—
—
—
0
0
808
7736
1.30
2.17
5.5
4.9
6.06
5.96
mmol/l
1.36
768
7126
25
138
1.83
2.11
3.8
3.0
7.82
8.85
pmol/l
0.26
25
138
830
7986
1.31
2.07
5.4
5.0
4.56
4.67
mmol/l
2.57
791
7476
840
8103
1.32
1.99
6.3
5.7
2.62
2.75
mmol/l
3.63
799
7555
7
21
3.35
1.96
2.4
2.1
22.14
13.50
%
—
7
16
31
187
1.68
1.96
2.3
2.4
82.62
148.16
ug/min
0.46
21
110
12
51
2.37
1.95
1.8
1.3
146.47
182.70
pmol/l
0.73
12
51
10
39
2.58
1.94
1.2
1.3
4.21
7.59
u/l
—
10
34
892
8689
1.44
1.94
29.2
22.0
251.55
248.53
e9/l
0.70
883
8475
869
8429
1.36
1.93
13.9
11.0
26.97
26.74
u/l
0.17
859
8179
23
128
1.82
1.91
1.1
1.1
1.48
2.40
u/ml
—
7
74
120
950
1.30
1.90
2.4
2.9
10.33
8.52
umol/l
0.26
106
846
62
442
1.43
1.89
2.0
3.8
4.47
4.50
pmol/l
0.09
52
401
892
8693
1.43
1.89
29.2
22.0
4.52
4.52
e12/l
0.11
880
8462
14
65
2.17
1.88
1.1
1.2
—
—
—
0
0
892
8694
1.43
1.88
29.2
22.0
6.78
6.64
e9/l
1.37
882
8458
8
28
2.87
1.86
1.3
2.4
40.04
41.73
g/l
—
8
28
123
980
1.29
1.86
6.0
9.9
1.28
0.96
mmol/l
0.36
103
809
80
599
1.37
1.85
2.4
2.8
102.60
196.41
ng/l
3.32
74
545
107
844
1.30
1.75
3.2
4.0
7.38
7.38
ph
0.30
61
475
19
103
1.86
1.72
1.6
2.0
—
—
—
0
0
127
1029
1.27
1.69
1.3
1.2
—
—
—
0
0
53
376
1.43
1.69
3.5
3.6
1.02
1.02
ratio
0.03
48
349
19
104
1.84
1.68
2.3
3.2
4.40
4.08
e9/l
0.26
19
104
10
40
2.52
1.67
2.1
3.9
376.60
1009.70
u/ml
—
10
40
6
19
3.17
1.66
1.0
1.0
—
—
—
0
0
6
19
3.17
1.66
1.0
1.0
—
—
—
0
0
6
19
3.17
1.66
1.0
1.0
—
—
—
0
0
112
896
1.28
1.66
1.3
1.3
—
—
—
0
0
11
49
2.26
1.64
1.3
1.1
20.34
27.13
umol/l
0.28
11
42
21
120
1.77
1.63
1.1
1.6
210.80
56.02
mu/l
0.85
21
109
29
182
1.61
1.62
1.1
1.2
—
—
—
0
0
821
7937
1.25
1.61
5.3
4.9
1.43
1.45
mmol/l
0.79
780
7380
72
544
1.35
1.60
1.3
1.2
—
—
—
0
0
34
224
1.54
1.56
1.6
1.4
161.59
267.22
ug/g
1.78
15
140
191
1635
1.21
1.55
1.7
1.7
420.99
30887060.90
pmol/l
1.69
170
1376
17
93
1.84
1.52
8.1
1.7
—
—
—
0
0
31
202
1.55
1.50
2.1
2.7
11.17
11.20
mg/l
0.01
31
183
17
94
1.82
1.48
1.2
1.5
—
—
nmol/l
—
0
0
107
868
1.26
1.44
1.8
2.6
1.79
1.81
%
0.06
94
769
9
40
2.26
1.40
1.0
1.3
11.67
11.15
mm/h
—
9
40
7
29
2.42
1.39
1.1
1.0
—
0.42
—
0
5
37
256
1.46
1.38
3.0
3.4
7.40
7.41
ph
0.37
37
250
342
3107
1.16
1.37
5.4
5.1
1.99
2.93
ug/l
1.90
322
2822
9
42
2.15
1.34
1.8
3.1
7.26
8.20
mmol/l
—
9
42
18
105
1.73
1.34
1.2
1.0
2.74
6.56
u/ml
—
8
50
145
1227
1.21
1.33
1.6
1.6
1317.51
1167.52
nmol/l
0.76
111
945
43
309
1.41
1.32
2.1
2.2
23.17
21.44
s
0.41
36
282
84
671
1.28
1.29
1.9
2.7
65.42
69.48
e9/l
0.55
60
490
97
790
1.25
1.28
2.5
2.5
30.76
41.02
u/l
2.14
78
672
10
48
2.09
1.28
1.8
3.1
16.63
16.63
%
—
10
48
17
100
1.71
1.24
1.1
1.2
—
—
—
0
0
55
421
1.33
1.17
1.1
1.1
—
—
—
0
0
781
7568
1.18
1.17
4.5
4.2
1.38
1.31
mmol/l
1.71
733
6985
373
3441
1.14
1.16
1.9
1.9
1.47
1.38
mmol/l
0.98
320
2887
29
199
1.47
1.15
4.5
3.3
0.78
2.46
index
2.21
18
109
32
225
1.44
1.13
4.8
1.5
—
—
—
0
0
133
1136
1.20
1.13
1.8
1.8
—
—
—
0
0
163
1420
1.18
1.11
3.1
3.8
0.80
0.82
mmol/l
1.10
155
1360
32
226
1.43
1.11
4.8
1.5
—
—
—
0
0
7
31
2.27
1.10
1.7
2.8
—
—
—
0
0
211
1880
1.16
1.08
3.4
3.0
0.68
0.79
ug/l
0.97
129
1178
31
219
1.43
1.08
1.7
2.0
1.72
4.08
iu/l
—
10
97
32
228
1.42
1.07
4.8
1.5
—
—
—
0
0
17
105
1.63
1.06
1.2
1.1
0.39
1.91
u/ml
—
5
44
22
146
1.52
1.04
2.1
3.2
57.74
57.42
%
0.04
22
146
5
22
2.28
1.03
1.0
1.7
—
—
—
0
0
11
60
1.84
1.03
1.5
1.1
97.91
112.77
pmol/l
0.30
11
60
7
34
2.07
1.03
1.1
1.0
—
0.25
—
0
7
9
47
1.92
1.02
1.0
1.0
—
—
—
0
0
15
91
1.66
1.01
1.0
1.4
—
—
—
0
0
15
91
1.66
1.01
2.5
2.6
1.03
2.00
g/24h
—
9
53
12
68
1.77
1.00
1.3
1.2
—
—
—
0
0
7
35
2.01
1.00
1.4
1.1
—
—
—
0
0
9
49
1.84
0.98
2.4
1.9
60.22
72.59
%
—
9
44
60
479
1.27
0.97
3.2
3.9
24.79
24.02
mmol/l
1.21
60
470
7
37
1.90
0.94
1.1
1.2
111.57
617.23
u/l
—
7
31
19
126
1.52
0.91
1.0
1.2
—
—
—
0
0
22
151
1.47
0.91
1.4
2.1
—
—
—
0
0
35
264
1.34
0.87
1.6
1.7
13.67
10.99
u/ml
—
9
76
28
204
1.38
0.86
5.3
1.5
—
—
—
0
0
25
179
1.41
0.84
4.6
3.5
—
—
—
0
0
6
31
1.94
0.84
1.7
2.3
48.00
51.42
umol/l
—
6
24
245
2244
1.12
0.84
1.4
1.4
—
—
—
0
0
30
224
1.35
0.80
5.1
1.5
—
—
—
0
0
60
493
1.23
0.79
1.6
1.7
—
—
—
0
0
6
33
1.82
0.79
7.3
3.3
40.72
30.29
mu/l
—
6
33
0
25
0.00
0.79
0.0
1.3
—
25.62
—
0
18
91
782
1.18
0.77
6.7
9.6
1.20
1.35
mmol/l
1.25
91
769
6
34
1.77
0.76
1.3
1.1
—
—
—
0
0
13
83
1.57
0.75
1.1
1.4
—
—
—
0
0
57
687
0.82
0.75
1.8
1.8
3.47
3.52
mmol/l
0.15
39
502
5
24
2.09
0.74
1.6
3.0
0.62
0.63
mmol/l
—
5
24
16
108
1.49
0.74
1.4
1.2
1.86
4.45
u/ml
—
7
49
341
3203
1.10
0.73
2.3
2.1
—
—
—
0
0
14
204
0.68
0.69
1.4
1.4
—
—
—
0
0
18
127
1.43
0.68
1.5
1.9
—
—
—
0
0
82
709
1.17
0.66
1.5
1.4
—
—
—
0
0
15
103
1.46
0.65
1.9
2.5
32.80
32.11
pg
0.27
15
103
71
824
0.85
0.64
1.4
1.4
—
—
—
0
0
94
826
1.15
0.63
3.4
3.9
2.44
1.62
mmol/l
1.73
86
693
29
226
1.29
0.62
3.6
3.8
2.16
4.25
ratio
0.60
15
128
6
104
0.57
0.62
1.3
1.1
—
—
—
0
0
22
165
1.34
0.61
6.5
1.5
—
—
—
0
0
80
697
1.16
0.60
2.1
2.4
6.28
8.18
ug/l
0.40
72
620
0
22
0.00
0.59
0.0
1.1
—
301.14
—
0
14
11
72
1.53
0.59
2.3
2.5
—
—
—
0
0
8
53
1.51
0.58
1.0
4.9
78.38
116.53
nmol/l
—
8
53
102
909
1.14
0.57
3.8
5.0
55.72
24.29
ug/l
0.27
82
762
34
278
1.23
0.52
4.1
3.9
132.38
698.43
mg/l
1.46
13
135
46
389
1.19
0.51
2.9
3.6
25.39
24.94
mmol/l
0.33
46
376
28
346
0.80
0.50
1.3
1.2
0.95
0.91
g/l
0.44
28
346
21
162
1.30
0.50
2.3
4.5
—
—
—
0
0
320
3360
0.93
0.50
3.2
3.2
—
—
—
0
0
22
171
1.29
0.50
5.0
3.4
16.64
26.64
mg/l
1.90
11
114
25
198
1.27
0.50
1.1
1.2
—
—
—
0
0
26
323
0.80
0.49
1.2
1.1
0.74
0.66
ratio
—
7
46
7
45
1.56
0.49
1.3
2.3
—
—
—
0
0
7
45
1.56
0.49
1.7
1.3
0.75
1.31
nmol/l
—
7
33
13
93
1.40
0.48
1.5
1.2
—
—
—
0
0
11
76
1.45
0.48
4.2
3.9
9.00
12.07
index
—
6
55
31
254
1.23
0.47
1.1
1.1
—
—
—
0
0
83
742
1.13
0.46
7.7
10.9
—
—
—
0
0
16
210
0.76
0.46
1.3
1.2
—
—
—
0
0
16
120
1.34
0.46
1.4
1.5
—
—
—
0
0
16
120
1.34
0.46
1.4
1.5
—
—
—
0
0
16
120
1.34
0.46
1.4
1.5
—
—
—
0
0
16
120
1.34
0.46
1.4
1.5
—
—
—
0
0
13
94
1.39
0.46
1.1
1.4
—
—
—
0
0
5
83
0.60
0.46
1.8
1.2
—
—
—
0
0
39
329
1.19
0.45
1.7
2.0
1.88
1.37
ug/l
0.15
33
304
79
707
1.13
0.44
3.4
4.5
7.32
7.35
ph
0.41
62
510
58
508
1.15
0.44
8.6
12.8
24.51
24.37
mmol/l
0.10
58
502
20
157
1.28
0.43
3.8
3.9
3.80
2.46
mmol/l
0.42
15
110
20
157
1.28
0.43
3.8
3.9
5.25
5.05
kpa
0.44
20
151
6
93
0.64
0.42
1.5
1.5
—
—
—
0
0
8
57
1.41
0.42
1.0
1.5
—
—
—
0
0
18
140
1.29
0.42
1.4
2.1
4.54
5.14
mmol/24h
0.43
18
123
5
33
1.52
0.41
1.0
1.2
—
36.22
—
0
9
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
8
59
1.36
0.41
1.5
1.9
39.65
38.58
%
—
8
59
28
336
0.83
0.40
1.3
1.2
1.53
1.54
g/l
0.07
28
336
26
215
1.22
0.38
1.1
1.2
—
1088.57
—
0
7
17
134
1.27
0.37
1.4
1.3
—
—
—
0
0
6
45
1.34
0.33
1.8
1.3
—
—
—
0
0
6
90
0.66
0.33
1.5
1.4
—
—
—
0
0
10
74
1.36
0.32
1.9
1.9
—
—
—
0
0
10
132
0.75
0.32
3.2
2.8
9.84
7.62
u/ml
—
10
127
66
602
1.10
0.30
4.3
3.5
—
—
—
0
0
27
232
1.17
0.29
1.3
1.8
276.78
323.05
mu/l
0.40
27
219
19
158
1.21
0.28
4.0
4.0
7.96
8.49
kpa
0.63
19
152
18
150
1.20
0.26
2.1
2.0
—
—
—
0
0
8
67
1.20
0.26
1.0
1.3
—
—
—
0
0
5
75
0.66
0.26
1.0
4.5
—
—
—
0
0
19
160
1.19
0.25
2.8
3.2
6.91
7.86
mmol/l
1.43
19
154
9
73
1.24
0.25
1.0
1.1
—
—
—
0
0
12
96
1.25
0.24
1.1
1.1
—
—
—
0
0
84
785
1.08
0.24
1.3
1.4
—
—
—
0
0
26
229
1.14
0.22
1.3
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
22
192
1.15
0.21
3.1
5.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
0.59
—
0
8
0
13
0.00
0.21
0.0
1.7
—
7.62
—
0
8
0
13
0.00
0.21
0.0
7.5
—
10.55
—
0
13
0
14
0.00
0.20
0.0
3.2
—
—
—
0
0
16
137
1.17
0.19
1.2
1.1
—
—
—
0
0
16
137
1.17
0.19
1.2
1.1
—
—
—
0
0
39
358
1.09
0.18
1.5
1.8
0.42
0.36
mg/l
0.22
22
182
7
62
1.13
0.17
1.6
1.2
—
—
—
0
0
22
196
1.13
0.16
1.5
1.6
—
—
—
0
0
6
80
0.75
0.15
1.3
1.3
—
—
—
0
0
9
81
1.11
0.15
2.1
2.9
—
—
—
0
0
35
324
1.08
0.14
1.3
1.1
213.00
119.10
titre
—
5
10
24
218
1.10
0.13
1.3
1.3
188.00
269.39
miu/ml
0.38
11
95
8
99
0.81
0.13
1.1
1.1
—
—
—
0
0
15
132
1.14
0.13
1.1
1.1
—
—
—
0
0
12
104
1.16
0.12
1.2
1.8
—
—
—
0
0
54
516
1.05
0.10
1.2
1.2
168.50
138.86
u/ml
0.18
19
190
57
547
1.04
0.09
6.9
10.8
25.29
24.78
mmol/l
0.40
57
540
6
55
1.09
0.09
2.7
4.0
1.00
0.84
index
—
6
55
35
332
1.06
0.08
1.3
1.2
—
—
—
0
0
6
72
0.83
0.07
1.7
1.1
—
—
—
0
0
8
76
1.05
0.07
1.3
1.2
—
—
—
0
0
12
108
1.11
0.07
1.3
2.5
—
—
—
0
0
7
83
0.84
0.07
2.1
1.4
—
—
—
0
0
15
163
0.92
0.07
1.8
1.6
—
—
—
0
0
22
230
0.96
0.03
2.8
3.7
64.90
61.53
%
0.27
22
222
15
144
1.04
0.00
1.5
1.5
152.36
159.51
au/ml
—
5
46
17
174
0.98
0.00
1.4
1.5
1136.08
966.33
mu/l
0.25
12
144
37
366
1.01
0.00
3.1
3.8
75.44
10571.34
u/ml
0.82
29
323
109
1094
1.00
0.00
1.3
1.3
—
—
—
0
0
42
418
1.01
0.00
1.6
1.6
—
—
—
0
0
12
125
0.96
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
62.31
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
359.00
—
0
5
0
8
0.00
-0.00
0.0
5.0
—
100.63
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
3.1
3.7
16.01
56.09
u/ml
—
7
72
0
8
0.00
-0.00
0.0
1.0
—
12.04
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
176.20
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
86
0.93
-0.00
3.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
2.35
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
24.00
—
0
5
5
50
1.00
-0.00
1.0
1.0
1645.40
1635.76
miu/ml
—
5
50
9
89
1.01
-0.00
2.9
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
0.57
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
228.12
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_CARTILAGE and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
M13_CARTILAGE 1.362 [1.0, 1.85] 0.05
Birth year 0.98 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 796 males with M13_CARTILAGE died.

Mortality risk

Mortality risk for people of age

years, who have M13_CARTILAGE.

N-year risk Females Males
1 No data 0.249%
5 No data 1.259%
10 No data 3.205%
15 No data 5.826%
20 No data 9.971%

Relationships between endpoints

Index endpoint: M13_CARTILAGE – Other articular cartilage disorders

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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