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Retinal haemorrhage

DOID EFO Endpoint Browser PheWeb

H7_RETINAHAEMORR

age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H35.6
  • Hospital discharge: ICD-9 — 3628A
  • Hospital discharge: ICD-8 — 37701
  • Cause of death: ICD-10 — H35.6
  • Cause of death: ICD-9 — 3628A
  • Cause of death: ICD-8 — 37701

2 out of 7 registries used, show all original rules.

1149

4. Check minimum number of events

None

1149

5. Include endpoints

None

1149

6. Filter based on genotype QC (FinnGen only)

985

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H35
Name in latin
Haemorrhagia retinae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6470 3761 2664
Only index persons 5746 3425 2321
Unadjusted period prevalence (%)
Whole population 0.09 0.11 0.07
Only index persons 0.11 0.13 0.09
Median age at first event (years)
Whole population 71.27 74.94 66.17
Only index persons 71.43 75.09 66.04

-FinnGen-

Key figures

All Female Male
Number of individuals 985 534 451
Unadjusted period prevalence (%) 0.20 0.19 0.21
Median age at first event (years) 69.86 69.73 70.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1022
Matched controls
10220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
49.4
321.2
190
47
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
19.3
316.8
273
189
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
497.8
307.7
310
9
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
15.0
307.7
346
337
H43.1
ICD-10 Finland
Vitreous haemorrhage
68.4
307.7
199
36
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
307.7
997
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
417.2
307.7
372
14
CKC12
NOMESCO Finland
Photocoagulation of retina
135.0
278.4
140
12
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
77.3
270.9
146
22
WX140
NOMESCO Finland
Parabulbar anesthesy
21.0
250.1
200
117
XCW99
NOMESCO Finland
Other investigative procedure of eye
10.6
235.3
308
401
XCK10
NOMESCO Finland
Photography of fundus of eye
8.2
167.2
260
407
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
387.0
138.3
136
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
27.7
112.0
77
30
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.4
100.3
330
991
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.5
98.2
312
911
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
132.3
90.7
96
8
XCD20
NOMESCO Finland
Photoangiography of eye
127.7
87.6
93
8
H33.0
ICD-10 Finland
Retinal detachment with retinal break
888.9
84.8
82
*
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
22.7
83.9
62
29
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
43.8
83.4
50
12
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
182.8
81.4
84
5
A10AA01, ,
ATC
15.8
77.4
68
46
A10AB01
ATC
insulin (human); parenteral
11.3
77.0
83
79
XCH00
NOMESCO Finland
Eye pressure measurement
6.6
69.7
120
202
CKD40
NOMESCO Finland
Endophotocoagulation of retina
714.3
68.9
67
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
19.9
67.9
53
28
A10AA02, ,
ATC
9.8
65.9
79
87
H34.8
ICD-10 Finland
Other retinal vascular occlusions
234.9
65.0
66
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
338.5
63.1
63
*
T89
ICPC
Diabetes insulin dependent
8.0
61.0
86
116
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.9
60.3
509
2610
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.2
59.0
179
491
A10AC01
ATC
insulin (human); parenteral
4.8
58.4
145
340
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
8.3
58.1
79
102
H43.8
ICD-10 Finland
Other disorders of vitreous body
4.2
57.2
176
487
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
589.7
57.2
56
*
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
21.3
56.9
43
21
H3603, E103,
ICD-10 Finland
+∞
56.8
54
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.7
54.6
525
2839
H26.4
ICD-10 Finland
After-cataract
3.6
52.7
200
639
A10AB04
ATC
insulin lispro; parenteral
8.5
52.6
70
88
H33.3
ICD-10 Finland
Retinal breaks without detachment
274.0
51.6
52
*
H04AA01
ATC
glucagon; nasal, parenteral
13.6
50.5
48
37
A10AB05
ATC
insulin aspart; parenteral
4.3
48.5
139
363
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
467.7
45.6
45
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
240.6
45.3
46
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
+∞
43.0
41
*
H36.01
ICD-10 Finland
Diabetic maculopathy
153.1
42.1
44
*
H3603, E113,
ICD-10 Finland
+∞
39.8
38
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
7.2
39.4
60
88
H53.1
ICD-10 Finland
Subjective visual disturbances
4.0
38.7
121
335
H36.00
ICD-10 Finland
Diabetic background retinopathy
391.5
38.3
38
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
37.7
36
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
6.8
36.1
58
90
E10
ICD-10 Finland
Type 1 diabetes mellitus
12.5
34.3
34
28
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
67.4
34.2
39
6
A10AE04
ATC
insulin glargine; parenteral
3.2
34.1
149
513
XCK00
NOMESCO Finland
Perimetry
4.0
33.8
104
284
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
93.3
32.9
36
*
ZXA10
NOMESCO Finland
Bilateral
2.5
32.4
256
1203
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
74.4
32.1
36
5
A10AE05
ATC
insulin detemir; parenteral
4.2
31.9
89
226
A10AE06
ATC
insulin degludec; parenteral
5.4
31.5
64
125
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
165.0
30.8
32
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
30.0
517
3331
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
46.5
29.8
36
8
S01ED51
ATC
timolol, combinations; ophthalmic
3.2
29.1
129
446
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.6
28.4
69
157
127
Kela drug reimbursment
Transplant complication
9.5
28.4
34
37
H53.4
ICD-10 Finland
Visual field defects
6.0
28.3
51
89
H3600, E113,
ICD-10 Finland
+∞
28.3
27
*
H3601, E103,
ICD-10 Finland
+∞
28.3
27
*
H3600, E103,
ICD-10 Finland
+∞
27.2
26
*
CKC15
NOMESCO Finland
Panretinal photocoagulation
77.3
26.9
30
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
41.3
25.9
32
8
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
24.8
25.8
36
15
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
6.3
25.6
44
73
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.6
25.6
63
145
XCW10
NOMESCO Finland
Assessment of vision
8.1
25.3
34
43
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
25.1
24
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
+∞
25.1
24
*
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
25.1
24
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
27.0
25.0
34
13
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
24.4
124
462
H25.1
ICD-10 Finland
Senile nuclear cataract
2.0
24.1
390
2405
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
24.1
23
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.4
23.5
90
284
ZX198
NOMESCO Finland
Other local administration
25.3
23.2
32
13
H25.8
ICD-10 Finland
Other senile cataract
2.5
23.1
171
770
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
85.4
22.8
25
*
A10AD01
ATC
insulin (human); parenteral
6.9
22.6
35
52
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
22.0
22.2
32
15
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
22.1
294
1680
H3601, E113,
ICD-10 Finland
+∞
22.0
21
*
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
117.6
21.7
23
*
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
61.4
20.9
24
*
H35.9
ICD-10 Finland
Retinal disorder, unspecified
61.4
20.9
24
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
214.2
20.6
21
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
20.4
559
4030
1LA05, ,
NOMESCO Finland
+∞
19.9
19
*
H33.5
ICD-10 Finland
Other retinal detachments
29.6
19.7
26
9
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.0
19.6
30
44
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.1
19.6
42
86
TK800
NOMESCO Finland
Hemodialysis
5.3
19.2
39
76
S01EC01
ATC
acetazolamide; systemic
5.0
19.1
41
84
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.2
18.9
178
885
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
18.8
18
*
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
18.7
319
1968
H35.37
ICD-10 Finland
Macular holes
193.4
18.6
19
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
17.9
710
5629
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
14.9
17.7
29
20
S01BC03
ATC
diclofenac; ophthalmic
5.2
17.5
36
71
AA1AD
NOMESCO Finland
CT of head and brain
1.8
17.2
365
2399
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
12.8
17.2
30
24
ZXA05
NOMESCO Finland
Left side
1.9
17.1
286
1746
C08CA01
ATC
amlodipine; oral
1.8
17.0
467
3306
B03XA02
ATC
darbepoetin alfa; parenteral
4.6
16.9
40
89
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.7
16.9
39
85
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
16.7
16
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
16.6
288
1775
WZC30
NOMESCO Finland
Teaching
2.0
16.0
188
1014
177
Kela drug reimbursment
Insulin glargine 300 U / ml
5.6
15.8
30
55
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
34.0
15.8
20
6
A11CC03
ATC
alfacalcidol; systemic
4.2
15.7
42
103
C03CA01
ATC
furosemide; systemic
1.7
15.7
416
2899
S01EA05
ATC
brimonidine; ophthalmic
3.9
15.6
47
126
ZXD05
NOMESCO Finland
Urgent procedure
1.8
15.6
323
2096
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.3
15.3
59
187
L04AA06
ATC
mycophenolic acid; systemic
5.7
15.1
28
50
H35.4
ICD-10 Finland
Peripheral retinal degeneration
57.6
14.8
17
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
25.5
14.7
20
8
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
21.4
14.7
21
10
H35.36
ICD-10 Finland
Macular cyst
+∞
14.6
14
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
14.5
162
855
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
152.1
14.5
15
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.6
14.5
89
365
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
12.8
14.4
25
20
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
19.5
14.3
21
11
137
Kela drug reimbursment
Uraemia requiring dialysis
13.6
14.2
24
18
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
14.0
81
322
C02AC05
ATC
moxonidine; oral
2.8
14.0
74
281
S18
ICPC
Laceration/cut
1.6
13.6
499
3745
37701
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia retinae et chorioideae
+∞
13.6
13
*
V03AE02
ATC
sevelamer; oral
26.1
13.4
18
7
WW200
NOMESCO Finland
Immunization
4.0
13.3
37
94
Z49.2
ICD-10 Finland
Other dialysis
15.3
13.1
21
14
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
28.8
13.0
17
6
F29
ICPC
Eye symptom/complaint other
2.2
13.0
121
596
H26.2
ICD-10 Finland
Complicated cataract
11.7
12.8
23
20
S01EE01
ATC
latanoprost; ophthalmic
2.4
12.8
90
393
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.9
12.8
23
40
L04AD01
ATC
ciclosporin; systemic
5.6
12.6
24
44
WX002
NOMESCO Finland
Sedation and analgesia
1.8
12.6
211
1274
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
12.5
12
*
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
12.5
12
*
3628A
ICD-9 Finland
Other retinal disorders[HAEMORRHAGIA RETINAE]
+∞
12.5
12
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
131.6
12.5
13
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.7
12.5
23
41
ZXA00
NOMESCO Finland
Right side
1.7
12.4
289
1918
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
4.3
12.3
32
77
N02BE01
ATC
paracetamol; systemic, rectal
2.1
12.2
908
8115
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
18.3
12.1
18
10
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
11.9
294
1979
S01BC05
ATC
ketorolac; ophthalmic
2.8
11.8
58
212
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
16.6
11.7
18
11
B05DA
ATC
Isotonic solutions
12.7
11.7
20
16
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
+∞
11.5
11
*
H3602, E103,
ICD-10 Finland
+∞
11.5
11
*
C07AB07
ATC
bisoprolol; oral
1.6
11.5
550
4338
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
121.3
11.4
12
*
A12AA04
ATC
calcium carbonate; oral
4.7
11.2
26
57
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
43.8
10.9
13
*
H57.1
ICD-10 Finland
Ocular pain
3.0
10.9
48
165
A10AA03, ,
ATC
9.0
10.8
22
25
Z94.0
ICD-10 Finland
Kidney transplant status
9.7
10.8
21
22
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
10.7
105
527
A02BC02
ATC
pantoprazole; systemic
1.6
10.6
690
5790
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.3
10.6
78
348
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
14.4
10.5
17
12
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
10.5
356
2579
H34.2
ICD-10 Finland
Other retinal artery occlusions
111.1
10.4
11
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
111.1
10.4
11
*
R42
ICD-10 Finland
Dizziness and giddiness
1.7
10.4
257
1720
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
10.4
10
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
16.2
10.4
16
10
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
10.4
121
647
C09CA01
ATC
losartan; oral
1.6
10.4
288
1987
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.8
10.2
31
84
J01DB01
ATC
cefalexin; oral
1.7
10.1
800
6986
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
10.1
139
785
C08CA13
ATC
lercanidipine; oral
1.8
10.0
180
1104
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
9.9
100
507
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.4
9.8
34
101
C10AA05
ATC
atorvastatin; oral
1.5
9.7
452
3494
L17
ICPC
Foot/toe symptom/complaint
1.6
9.7
314
2239
SPAT1263
SPAT
Sampling
1.5
9.7
407
3078
T90
ICPC
Diabetes non-insulin dependent
1.6
9.7
257
1748
A98
ICPC
Health maint/preventive medicine
2.1
9.6
945
8706
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
9.6
379
2829
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
9.5
259
1771
L04AD02
ATC
tacrolimus; systemic
9.2
9.5
19
21
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
15.2
9.5
15
10
CKC20
NOMESCO Finland
Cryopexy of undetached retina
100.9
9.4
10
*
L28
ICPC
Limited function/disability (L)
1.6
9.4
233
1557
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
9.4
9
*
H3603, E107,
ICD-10 Finland
+∞
9.4
9
*
B05DB
ATC
Hypertonic solutions
12.5
9.4
16
13
H16.0
ICD-10 Finland
Corneal ulcer
2.5
9.2
56
229
H40.0
ICD-10 Finland
Glaucoma suspect
2.1
9.1
88
439
F05
ICPC
Visual disturbance other
2.9
9.0
42
149
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
10.1
9.0
17
17
H44.1
ICD-10 Finland
Other endophthalmitis
37.0
9.0
11
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.5
9.0
58
244
H53.8
ICD-10 Finland
Other visual disturbances
4.3
8.9
23
55
SPAT1325
SPAT
Vaccination
1.5
8.9
352
2618
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
4.9
8.9
19
39
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.8
8.8
43
157
J01MA02
ATC
ciprofloxacin; systemic
1.5
8.8
394
3007
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
3.8
8.7
26
70
F16
ICPC
Eyelid symptom/complaint
2.5
8.6
55
230
S01BA07
ATC
fluorometholone; ophthalmic
4.6
8.6
20
44
SPAT1262
SPAT
Handing over of treatment supplies
1.7
8.6
178
1133
205
Kela drug reimbursment
Chronic hypertension
1.5
8.6
312
2274
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
10.1
8.5
16
16
Z49.0
ICD-10 Finland
Preparatory care for dialysis
7.4
8.5
19
26
V03AE01
ATC
polystyrene sulfonate; oral
4.4
8.4
21
49
H44.2
ICD-10 Finland
Degenerative myopia
90.8
8.4
9
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
8.3
234
1607
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
8.3
8
*
CKD90
NOMESCO Finland
Removal of subretinal haematoma
+∞
8.3
8
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
8.6
8.3
17
20
C09AA02
ATC
enalapril; systemic
1.6
8.3
221
1500
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
8.2
298
2167
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
8.2
651
5538
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
8.1
186
1214
R04.0
ICD-10 Finland
Epistaxis
2.0
8.1
94
501
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
8.1
364
2768
H44.0
ICD-10 Finland
Purulent endophthalmitis
33.6
8.1
10
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
8.1
394
3045
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.2
8.0
31
99
C10AX09
ATC
ezetimibe; oral
1.7
7.8
170
1097
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
6.4
7.7
19
30
R06.0
ICD-10 Finland
Dyspnoea
1.5
7.7
291
2131
Z01.2
ICD-10 Finland
Dental examination
1.5
7.6
393
3060
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.8
7.6
122
723
Z3231
NOMESCO Finland
Registered nurse
1.5
7.5
265
1913
J01MA12
ATC
levofloxacin; systemic
1.6
7.5
190
1272
S29
ICPC
Skin symptom/complaint other
1.6
7.5
201
1364
R05
ICPC
Cough
1.5
7.4
236
1666
M79.6
ICD-10 Finland
Pain in limb
1.4
7.3
419
3321
B01AC04
ATC
clopidogrel; oral
1.6
7.3
192
1295
H3603, E106,
ICD-10 Finland
+∞
7.3
7
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
7.3
7
*
R51.80
ICD-10 Finland
Headache
1.7
7.3
143
896
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
6.3
7.3
18
29
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.5
7.3
44
180
SPAT1229
SPAT
Assessment of need for aid
1.9
7.2
92
506
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
7.2
81
428
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
7.2
286
2113
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.7
7.1
36
134
C02CA01
ATC
prazosin; oral
3.5
7.1
24
70
PA2AD
NOMESCO Finland
CT angiography of brain
8.0
7.1
15
19
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
6.1
7.1
18
30
L04AA01
ATC
[U] ciclosporin
5.7
7.1
19
34
ZYC01
NOMESCO Finland
Remote contact by phone
2.2
7.1
57
265
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
7.1
218
1525
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.0
244
1750
F38
ICPC
Eye, Other laboratory test NEC
3.5
7.0
23
66
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
4.4
7.0
17
39
J01FF01
ATC
clindamycin; systemic
1.5
7.0
252
1824
H02AB04
ATC
methylprednisolone; systemic
1.7
6.9
141
891
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
4.0
6.9
19
48
WX199
NOMESCO Finland
Other local analgesia
2.5
6.8
42
173
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
9.4
6.8
13
14
Z2446
NOMESCO Finland
Social worker
2.1
6.8
65
324
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
40.3
6.8
8
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
6.8
175
1175
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
16.8
6.8
10
6
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
3.3
6.7
24
73
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.7
6.7
35
133
SPAT1310
SPAT
Counselling related to known health issue
1.5
6.7
292
2192
SPAT1312
SPAT
General health counselling
1.5
6.7
278
2067
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
6.7
123
757
H54.1
ICD-10 Finland
Severe visual impairment, binocular
22.7
6.7
9
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
6.7
256
1873
E0000UV, ,
ATC
1.4
6.7
385
3044
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
6.7
408
3260
J01CA04
ATC
amoxicillin; systemic
1.5
6.6
759
6768
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
4.1
6.6
18
45
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
4.1
6.6
18
45
SPAT1260
SPAT
Consultation of another employee
1.6
6.6
167
1114
S01ED01
ATC
timolol; ophthalmic
2.5
6.6
41
170
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
6.6
201
1401
R05
ICD-10 Finland
Cough
1.5
6.6
199
1384
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.1
6.5
60
294
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
10.1
6.5
12
12
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.6
6.5
36
141
H28.0
ICD-10 Finland
Diabetic cataract
70.3
6.4
7
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
6.4
168
1130
S97
ICPC
Chronic ulcer skin
1.9
6.4
75
402
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.8
6.4
19
51
RS222, ,
NOMESCO Finland
4.1
6.4
17
42
J01CF05
ATC
flucloxacillin; systemic
2.0
6.4
71
374
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
6.4
469
3860
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
6.3
163
1092
S01EA03
ATC
apraclonidine; ophthalmic
6.0
6.3
16
27
L14
ICPC
Leg/thigh symptom/complaint
1.8
6.3
87
492
S01EC03
ATC
dorzolamide; ophthalmic
3.4
6.3
22
66
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
6.3
136
873
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
6.3
94
545
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
+∞
6.3
6
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
6.3
6
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
6.3
6
*
CKA10
NOMESCO Finland
Biopsy of vitreous body
26.8
6.2
8
*
K99
ICPC
Cardiovascular disease other
2.7
6.2
33
127
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.4
6.2
17
32
XKD00
NOMESCO Finland
Uroflowmetry
1.6
6.2
156
1041
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.2
454
3730
A28
ICPC
Limited function/disability NOS
1.5
6.1
219
1577
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
6.1
184
1278
C10AA01
ATC
simvastatin; oral
1.4
6.0
450
3701
M65.3
ICD-10 Finland
Trigger finger
2.3
6.0
45
203
K85
ICPC
Elevated blood pressure
1.5
6.0
184
1281
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
6.0
72
389

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
716
5355
2.13
26.31
8.7
5.1
7.32
6.73
mmol/l
5.92
690
5108
649
4825
1.95
22.39
13.0
7.2
1.21
1.21
mmol/l
0.95
552
4128
605
4472
1.86
20.36
24.0
17.2
1.37
1.31
inr
1.67
513
3756
445
3030
1.83
19.16
4.6
3.3
95.31
45.17
mg/l
2.95
291
1950
259
1484
2.00
18.92
2.7
1.9
29.65
29.59
s
0.07
253
1440
281
1661
1.95
18.73
4.3
2.6
12.54
12.23
umol/l
0.31
263
1532
263
1537
1.96
18.04
4.3
2.5
2.22
2.27
g/l
0.79
247
1406
454
3152
1.79
17.99
4.6
3.3
6.36
7.28
mmol/l
5.32
368
2642
454
3177
1.77
17.32
3.8
3.4
2198.60
1606.45
ng/l
1.06
406
2764
50
131
3.96
17.15
2.0
1.3
115.20
170.98
au/ml
2.06
15
37
809
6736
1.96
16.95
12.2
8.1
84.62
80.10
u/l
1.35
772
6358
385
2580
1.79
16.94
3.0
2.3
2.81
2.91
mg/l
0.39
331
2183
443
3102
1.76
16.68
5.6
3.9
19.98
7.76
mg/mmol
2.98
289
1931
577
4357
1.74
16.57
12.9
6.5
1.21
1.21
mmol/l
1.22
527
3990
425
2954
1.75
16.33
2.6
2.2
260.31
238.79
u/l
0.10
402
2801
32
61
5.38
16.16
1.3
1.2
—
—
—
0
0
243
1438
1.91
15.80
4.5
2.5
23.01
21.76
%
0.73
228
1325
50
140
3.70
15.63
1.9
1.3
—
—
—
0
0
179
958
2.05
15.53
4.0
2.5
71.80
66.80
e9/l
0.82
142
717
428
3021
1.72
15.28
8.8
5.7
—
—
—
0
0
928
8243
2.37
14.68
27.4
17.9
24.50
26.67
mg/l
1.33
813
6917
223
1319
1.88
14.38
13.3
5.3
1.13
1.03
mmol/l
4.74
211
1200
522
3929
1.67
14.35
4.6
3.0
160.08
133.48
ug/l
0.84
482
3602
212
1237
1.90
14.24
4.0
2.5
1.83
1.79
%
0.23
188
1109
946
8499
2.52
14.13
34.1
21.8
139.31
139.60
mmol/l
2.50
934
8326
946
8508
2.50
13.93
34.9
21.9
4.03
3.99
mmol/l
3.23
931
8318
256
1606
1.79
13.56
5.8
3.2
0.83
0.81
mmol/l
1.09
238
1501
431
3120
1.66
13.53
4.8
3.6
44.48
83.10
e6/l
0.88
355
2427
162
878
2.00
13.47
16.9
6.4
11.89
10.68
mmol/l
1.33
153
836
398
2831
1.66
13.32
6.0
4.4
—
—
—
0
0
552
4268
1.64
13.23
2.6
2.2
92.42
95.21
pmol/l
0.76
290
2213
572
4463
1.64
13.22
8.0
5.8
0.62
0.60
e9/l
1.47
506
3789
490
3679
1.64
13.21
5.0
4.2
46.65
83.58
ng/l
0.83
390
2792
340
2328
1.69
13.12
4.1
2.8
358.87
350.12
umol/l
0.76
296
2016
573
4479
1.64
13.09
8.0
5.8
0.04
0.04
e9/l
0.07
507
3808
886
7807
2.01
13.07
9.2
6.7
42.66
39.55
mmol/mol
11.93
809
7222
46
138
3.44
13.00
1.7
1.2
237.37
285.17
u/ml
0.48
35
76
471
3513
1.63
12.96
5.7
4.2
146.79
119.21
e6/l
0.21
364
2524
579
4545
1.63
12.94
8.2
5.8
2.03
1.83
e9/l
0.62
523
3957
290
1909
1.72
12.90
2.0
1.7
1.38
1.39
mg/l
0.01
239
1502
585
4609
1.63
12.84
8.6
6.1
0.19
0.19
e9/l
0.10
519
3994
958
8722
2.57
12.71
35.4
23.8
90.72
80.39
umol/l
5.36
950
8597
593
4699
1.62
12.61
5.4
4.2
0.00
0.31
estimate
0.50
122
964
608
4852
1.62
12.53
9.3
6.4
11.55
11.98
umol/l
0.39
573
4636
183
1060
1.88
12.45
6.8
3.5
7.38
7.38
ph
0.14
102
619
584
4619
1.62
12.45
5.3
4.2
0.00
0.00
estimate
-0.00
121
987
900
8011
2.03
12.33
6.3
5.2
4.30
4.53
mmol/l
9.53
823
7373
590
4687
1.61
12.27
5.4
4.2
0.00
1.59
estimate
0.50
128
1023
176
1022
1.87
11.84
7.6
3.4
1.85
2.08
mmol/l
0.33
159
875
946
8608
2.33
11.80
17.9
12.3
24.73
25.14
u/l
0.36
916
8330
709
5924
1.64
11.71
6.5
5.2
2426.88
1945.80
e6/l
—
8
99
529
4133
1.58
11.50
8.9
6.0
8.93
8.97
%
0.09
505
3857
909
8165
2.02
11.44
7.1
6.0
2.41
2.62
mmol/l
10.43
830
7467
117
598
2.08
11.36
8.0
3.4
24.09
24.46
mmol/l
0.56
117
591
535
4202
1.57
11.29
8.8
6.0
26.18
26.71
%
0.45
515
3969
963
8856
2.51
11.26
40.9
26.9
91.51
91.51
fl
0.01
956
8738
963
8857
2.51
11.24
41.1
27.0
238.88
245.22
e9/l
2.08
947
8660
487
3746
1.57
11.24
4.5
3.7
6.27
6.27
ph
0.03
240
2071
155
878
1.90
11.23
13.3
8.2
—
—
—
0
0
963
8859
2.51
11.20
42.1
27.5
39.12
39.76
%
2.90
955
8735
963
8859
2.51
11.20
41.0
27.1
7.12
6.83
e9/l
1.56
940
8636
963
8859
2.51
11.20
41.0
27.0
4.35
4.41
e12/l
2.94
944
8639
963
8859
2.51
11.20
40.8
26.9
30.30
30.39
pg
0.75
956
8741
537
4228
1.57
11.16
8.1
4.9
34.88
35.06
g/l
0.32
497
3938
963
8861
2.50
11.16
41.5
27.2
130.44
133.00
g/l
5.45
956
8744
619
5054
1.57
10.81
12.5
9.3
4.47
4.16
e9/l
1.81
562
4386
525
4133
1.56
10.77
9.0
6.0
0.63
0.66
%
0.37
500
3851
33
90
3.76
10.75
1.4
1.2
—
—
—
0
0
149
846
1.89
10.69
2.9
2.5
6.69
6.31
ug/l
0.13
134
734
18
14
13.06
10.67
1.0
1.0
—
—
—
0
0
314
2204
1.61
10.55
3.9
2.8
5.32
5.86
e6/l
0.21
289
2014
370
2701
1.58
10.53
4.8
3.5
0.58
0.46
e6/l
0.41
295
2027
142
799
1.90
10.47
5.2
3.5
114.82
90.93
ng/l
1.29
123
677
887
7954
1.87
10.46
6.3
5.1
1.42
1.46
mmol/l
1.96
805
7258
523
4131
1.54
10.45
8.8
5.9
2.78
2.84
%
0.21
499
3856
252
1679
1.66
10.41
3.6
3.1
0.92
1.08
e6/l
0.38
148
935
318
2251
1.60
10.27
3.7
2.4
—
—
—
0
0
123
666
1.96
10.15
3.4
2.8
10.00
10.93
g/l
1.47
111
600
398
2974
1.55
10.13
4.2
2.5
—
—
—
0
0
392
2920
1.56
10.11
1.9
1.7
20.56
19.94
nmol/l
0.35
332
2451
265
1803
1.63
10.03
1.8
1.8
1212.55
1190.67
nmol/l
0.13
198
1337
413
3120
1.54
9.96
3.8
3.5
—
—
—
0
0
109
571
2.02
9.88
5.4
2.5
1.26
1.19
%
0.27
109
566
17
14
12.33
9.87
1.0
1.1
—
—
—
0
0
205
1316
1.70
9.67
2.9
2.0
—
—
—
0
0
859
7683
1.74
9.51
6.5
5.4
1.99
2.02
mu/l
0.28
783
7008
148
870
1.82
9.48
3.5
3.0
65.59
66.38
g/l
0.50
130
800
520
4161
1.51
9.39
4.3
2.8
—
—
estimate
—
0
0
853
7622
1.72
9.38
5.4
4.3
1.30
1.28
mmol/l
0.42
763
6887
387
2915
1.53
9.30
9.1
4.1
7.40
7.40
ph
0.05
271
2131
319
2303
1.56
9.29
6.4
4.2
86.63
87.06
%
0.10
314
2265
514
4115
1.50
9.19
8.7
5.9
58.27
58.03
%
0.15
495
3909
501
3994
1.50
9.12
3.4
2.4
80.02
79.32
nmol/l
0.20
450
3535
52
207
2.59
9.01
1.6
1.3
—
—
—
0
0
26
68
3.90
9.00
1.2
1.3
—
—
—
0
0
883
7991
1.77
8.96
6.3
5.4
6.36
5.98
mmol/l
7.25
796
7234
172
1074
1.72
8.93
2.2
1.7
—
—
—
0
0
101
536
1.98
8.82
2.6
1.8
1.76
1.50
g/l
0.20
87
482
97
508
2.00
8.79
2.0
1.8
1.38
1.58
g/l
1.56
80
449
378
2860
1.51
8.77
4.3
2.5
59.81
90.70
u/l
0.56
335
2647
148
892
1.77
8.69
6.1
4.5
7.37
7.36
ph
0.19
111
632
49
194
2.60
8.59
2.9
2.3
77.72
74.86
ug/min
0.03
31
116
136
806
1.79
8.45
2.2
1.6
—
—
—
0
0
14
11
12.88
8.38
1.4
1.0
—
—
—
0
0
67
310
2.24
8.37
3.2
2.0
20.51
21.09
s
0.53
61
282
34
112
3.11
8.34
1.6
1.3
—
—
—
0
0
227
1548
1.60
8.34
3.8
3.3
2.65
2.24
e6/l
0.28
125
807
41
154
2.73
7.98
6.2
1.4
1.03
0.91
nmol/l
0.19
35
126
113
644
1.85
7.97
5.0
3.0
124.01
127.93
g/l
1.08
113
628
153
958
1.70
7.82
2.2
1.6
—
—
—
0
0
111
635
1.84
7.73
4.5
3.8
7.41
7.42
ph
0.41
99
533
347
2635
1.48
7.68
6.1
4.3
0.00
0.01
estimate
0.96
107
905
262
1891
1.52
7.38
4.3
3.1
499.21
529.01
mosm/kgh2o
1.62
235
1656
909
8396
1.75
7.27
23.5
16.1
—
—
—
0
0
734
6460
1.48
7.26
5.0
4.3
15.21
15.01
pmol/l
1.24
658
5843
161
1044
1.64
7.19
2.2
1.5
—
—
—
0
0
408
3230
1.44
7.14
4.0
3.9
—
0.67
—
0
12
74
381
2.02
7.06
1.3
1.5
—
16.93
—
0
8
417
3324
1.43
6.98
3.6
3.4
2.35
2.36
mmol/l
0.59
370
2990
35
132
2.71
6.79
1.2
1.1
—
—
—
0
0
57
271
2.17
6.70
1.5
1.5
289.92
276.16
ug/g
0.21
38
161
418
3355
1.42
6.64
2.1
2.2
—
—
—
0
0
257
1885
1.49
6.61
5.6
4.2
215.53
348.37
ng/l
0.80
214
1566
65
329
2.04
6.51
1.3
1.2
—
—
—
0
0
131
829
1.67
6.41
2.2
2.0
390.94
385.92
nmol/l
0.10
122
762
41
173
2.43
6.36
1.2
1.2
70.04
43.76
u/l
0.47
33
152
53
253
2.15
6.19
3.8
2.5
58.86
60.60
%
0.21
53
248
226
1642
1.48
6.04
1.7
1.5
2.64
2.55
g/l
0.10
140
948
166
1135
1.55
5.89
1.3
1.3
612.38
497.28
titre
0.31
42
243
128
826
1.63
5.80
2.7
2.5
0.43
0.55
e6/l
0.30
123
787
15
29
5.23
5.40
1.0
1.1
1820.47
1372.62
miu/ml
0.81
15
29
14
25
5.66
5.38
2.1
1.4
—
—
—
0
0
163
1135
1.52
5.31
2.3
1.8
—
—
—
0
0
154
1065
1.53
5.18
12.0
7.7
95.31
95.42
%
0.10
148
1028
11
15
7.40
5.15
5.5
3.3
—
—
—
0
0
244
1850
1.42
5.12
6.0
4.5
—
—
—
0
0
409
3385
1.35
4.99
2.2
1.9
1.30
1.32
mmol/l
0.20
330
2818
23
83
2.81
4.90
1.0
1.2
—
—
—
0
0
168
1198
1.48
4.87
11.7
7.5
5.05
5.12
kpa
0.49
160
1149
168
1198
1.48
4.87
12.3
7.5
7.42
7.41
ph
0.67
89
684
454
3827
1.34
4.86
17.5
12.0
0.03
0.00
e9/l
0.62
376
3130
168
1199
1.48
4.84
11.7
7.4
11.47
11.90
kpa
0.62
160
1153
126
846
1.56
4.84
4.1
2.5
51.70
91.59
u/l
0.30
104
715
149
1046
1.50
4.66
5.7
2.7
9.28
8.58
umol/l
0.12
129
912
27
109
2.52
4.66
1.1
1.3
0.56
0.66
nmol/l
1.29
27
103
240
1843
1.39
4.64
1.4
1.3
1.85
1.73
u/ml
0.05
67
471
414
3463
1.33
4.60
5.7
4.3
1.05
0.68
estimate
0.12
97
803
116
774
1.56
4.58
6.2
4.0
1.03
0.57
%
1.29
59
236
25
98
2.59
4.57
2.0
2.1
9.65
10.42
%
0.36
25
98
37
174
2.17
4.55
3.6
1.5
—
—
—
0
0
121
817
1.55
4.53
6.1
4.1
1.32
0.92
%
0.58
57
252
25
99
2.56
4.49
1.2
1.2
2.86
7.82
u/ml
0.93
14
44
16
49
3.30
4.48
2.0
1.7
—
52.54
—
0
5
30
130
2.35
4.46
1.2
1.1
—
—
—
0
0
11
19
5.84
4.45
2.2
1.4
—
—
—
0
0
163
1187
1.44
4.22
11.9
7.5
0.86
1.13
mmol/l
0.43
136
960
84
532
1.63
4.13
1.8
1.5
—
—
—
0
0
8
10
8.05
4.06
6.0
15.0
6.81
4.84
mmol/l
—
8
10
66
394
1.72
4.06
4.2
2.7
10.98
10.53
g/l
0.26
56
353
14
37
3.82
3.90
2.4
2.6
4978.21
1233.03
u/ml
0.42
14
37
7
8
8.80
3.77
2.0
1.4
—
—
—
0
0
600
5366
1.29
3.76
4.0
3.3
56.25
50.77
u/l
0.66
544
5001
115
801
1.49
3.74
1.6
1.4
—
—
—
0
0
22
90
2.48
3.73
1.1
1.2
—
—
—
0
0
256
2050
1.33
3.71
3.2
3.0
2.46
2.46
mmol/l
0.18
232
1832
40
211
1.93
3.67
6.5
3.9
—
—
—
0
0
25
112
2.26
3.50
4.2
2.3
1.36
0.90
g/24h
0.63
18
62
291
2393
1.30
3.46
3.2
3.3
0.00
0.07
—
7
73
71
452
1.61
3.46
4.3
4.1
—
—
—
0
0
119
855
1.44
3.32
3.5
3.1
191.62
232.32
ng/l
1.02
109
798
32
162
2.01
3.32
1.5
1.1
—
—
—
0
0
334
2816
1.28
3.24
4.4
3.3
32.90
33.30
u/l
0.08
312
2653
109
774
1.46
3.24
5.9
4.2
0.17
0.12
%
0.32
46
210
39
214
1.86
3.22
2.2
1.3
686.71
536.55
mg/l
0.25
34
200
60
376
1.63
3.13
3.6
3.8
57.52
206.43
mg/l
0.53
49
326
110
788
1.44
3.13
6.4
4.4
0.48
0.13
%
1.12
48
202
192
1510
1.33
3.12
1.3
1.3
27.08
37.70
iu/ml
0.77
40
471
55
339
1.66
3.07
3.7
3.8
1.89
2.82
ratio
0.85
31
194
317
2671
1.27
3.06
8.9
6.5
—
—
—
0
0
25
119
2.13
3.06
2.9
2.0
213.42
3416.32
u/l
—
9
39
55
341
1.65
3.00
2.1
1.8
9.01
7.85
iu/ml
0.10
15
81
11
31
3.58
2.99
1.4
1.2
—
—
—
0
0
5
5
10.04
2.98
1.4
1.0
—
—
—
0
0
5
5
10.04
2.98
4.0
7.6
—
—
—
0
0
72
479
1.54
2.94
1.3
1.4
63.00
49.77
au/ml
—
5
34
59
376
1.60
2.90
3.6
3.8
40.41
50.71
mg/l
0.49
48
326
159
1230
1.35
2.88
1.3
1.2
—
—
—
0
0
35
193
1.84
2.87
7.7
4.7
2.10
2.57
mmol/l
0.51
25
128
150
1152
1.35
2.85
1.2
1.3
—
—
—
0
0
26
130
2.03
2.82
2.4
1.4
—
—
—
0
0
26
130
2.03
2.82
2.4
1.4
—
—
—
0
0
26
130
2.03
2.82
2.4
1.4
—
—
—
0
0
26
130
2.03
2.82
2.4
1.4
—
—
—
0
0
22
103
2.16
2.82
1.2
1.3
—
—
—
0
0
22
103
2.16
2.82
1.4
1.3
314.94
284.43
pmol/l
0.14
17
94
98
702
1.44
2.80
6.4
4.2
—
—
—
0
0
273
2284
1.27
2.76
1.4
1.4
—
—
—
0
0
36
203
1.80
2.76
2.1
1.8
2.29
32.50
iu/l
0.53
19
81
32
174
1.87
2.75
2.0
1.4
—
—
—
0
0
117
870
1.39
2.72
2.4
2.2
0.00
0.02
estimate
0.50
21
167
12
40
3.02
2.70
2.6
2.4
22.08
20.36
nmol/l
0.11
12
35
121
907
1.38
2.68
2.7
2.2
0.21
0.20
g/l
0.13
116
837
11
35
3.17
2.65
1.2
1.9
1.85
1.07
nmol/l
0.93
11
28
38
221
1.75
2.64
1.2
1.2
2.39
2.76
u/ml
—
7
23
106
779
1.40
2.64
10.8
4.0
1.22
1.23
mmol/l
0.04
91
670
335
2888
1.24
2.58
5.7
5.8
2.19
2.53
ug/l
0.45
296
2582
128
975
1.36
2.57
1.3
1.3
—
—
—
0
0
33
186
1.80
2.55
5.6
2.9
58.36
58.69
%
0.04
33
186
15
63
2.40
2.47
2.0
1.8
39.81
38.68
%
0.10
15
63
54
352
1.56
2.45
3.9
3.5
1335.89
418.27
mg/l
0.48
27
146
13
51
2.57
2.45
1.0
1.1
—
—
—
0
0
10
32
3.15
2.44
1.3
1.4
121.10
177.52
mmol/24h
—
10
32
41
250
1.67
2.43
2.3
1.5
16307.43
16144.11
e6/l
0.01
30
173
48
305
1.60
2.43
1.4
1.2
1.06
1.83
u/ml
—
9
16
8
22
3.66
2.36
3.5
1.2
—
—
—
0
0
13
52
2.52
2.36
1.5
2.9
37.00
37.23
%
—
6
27
239
2003
1.25
2.36
2.0
1.7
69780646.71
6915983.43
pmol/l
0.43
182
1634
19
91
2.11
2.34
1.5
1.6
24.63
39.47
ng/l
0.56
19
91
25
133
1.90
2.33
10.3
6.0
11.97
12.83
mg/l
0.46
25
124
128
991
1.33
2.32
2.1
2.2
130.53
130.28
ug/g
0.00
98
787
64
439
1.49
2.32
2.4
2.2
0.00
0.01
estimate
0.50
13
135
9
28
3.23
2.31
2.2
1.5
29.33
31.75
%
—
9
28
14
59
2.39
2.30
2.6
1.5
131.79
98.02
ng/l
0.60
14
59
74
524
1.44
2.29
2.6
2.6
20.29
21.50
au/ml
—
10
40
43
271
1.61
2.26
1.8
1.4
0.23
0.24
g/l
0.12
43
260
44
280
1.60
2.23
1.9
1.4
1.17
1.21
g/l
0.46
44
266
24
128
1.90
2.23
3.3
1.7
33.29
32.60
pg
0.38
24
128
10
35
2.88
2.21
3.2
3.4
—
—
—
0
0
60
411
1.49
2.20
1.1
1.2
—
—
—
0
0
29
168
1.75
2.09
2.4
1.3
—
—
—
0
0
37
231
1.62
2.04
1.1
1.2
247.14
96.52
titre
—
7
23
134
1066
1.30
2.02
3.5
3.1
5.00
4.96
e9/l
0.02
109
902
246
2104
1.22
1.99
5.9
4.4
1.02
1.02
kg/l
0.01
159
1404
39
249
1.59
1.98
3.3
3.4
1.52
2.16
index
0.34
21
130
173
1427
1.26
1.95
1.3
1.3
11.73
13.01
u/ml
0.07
55
500
14
64
2.20
1.95
1.3
1.2
—
88.80
—
0
5
9
33
2.74
1.93
3.4
3.5
—
—
—
0
0
40
259
1.57
1.92
1.3
1.1
—
—
—
0
0
41
268
1.55
1.89
27.5
10.9
—
—
—
0
0
19
100
1.92
1.86
1.2
1.3
—
—
nmol/l
—
0
0
61
435
1.43
1.86
2.3
1.9
2.23
1.58
ug/l
0.34
55
387
11
46
2.41
1.85
1.0
1.0
—
—
—
0
0
6
17
3.54
1.84
34.7
7.6
7.60
4.95
kpa
—
6
17
277
2416
1.20
1.83
4.8
3.7
2.63
0.05
estimate
0.48
95
770
23
130
1.79
1.82
1.3
1.9
0.67
0.87
g/l
0.46
13
105
19
104
1.84
1.68
1.8
1.5
49.92
64.34
%
0.74
13
62
25
149
1.69
1.68
3.0
2.2
—
—
—
0
0
33
212
1.58
1.67
1.3
1.3
77.77
59.47
mmol/l
0.97
26
173
18
97
1.87
1.67
8.1
4.1
—
—
—
0
0
6
19
3.17
1.66
1.2
1.4
—
—
—
0
0
30
189
1.61
1.64
2.5
1.3
5.05
61.42
e6/l
0.98
22
146
34
508
0.66
1.63
1.4
1.4
—
—
—
0
0
20
113
1.79
1.61
5.3
5.9
9.02
7.20
mmol/l
0.49
15
94
6
20
3.01
1.58
1.5
1.8
69.83
97.70
nmol/24h
—
6
20
30
192
1.58
1.55
2.6
1.3
223.38
819.06
e6/l
0.49
24
151
81
626
1.32
1.55
1.9
2.2
14.30
12.87
nmol/l
0.66
69
563
63
470
1.36
1.52
1.8
1.7
—
—
—
0
0
7
27
2.60
1.51
1.1
1.2
—
—
—
0
0
6
21
2.87
1.50
1.0
1.1
26.00
27.10
s
—
6
21
10
45
2.23
1.46
1.9
2.3
305.10
240.38
e6/l
—
10
40
11
52
2.13
1.44
1.5
1.3
—
—
—
0
0
10
46
2.19
1.40
4.8
3.9
109.20
145.20
nmol/l
—
10
46
35
239
1.48
1.38
1.6
1.6
—
—
—
0
0
18
105
1.73
1.33
1.1
1.1
1.44
1.50
g/l
0.23
18
92
53
394
1.36
1.33
2.5
2.8
—
—
—
0
0
29
192
1.53
1.33
1.9
1.8
49.31
41.31
nmol/l
0.89
29
183
57
430
1.34
1.31
1.4
1.2
—
—
—
0
0
24
153
1.58
1.29
2.1
1.4
8.35
9.16
u/l
0.17
19
117
14
77
1.83
1.25
1.4
1.2
—
—
—
0
0
13
70
1.87
1.24
1.8
2.2
—
—
—
0
0
18
108
1.68
1.23
2.7
2.3
—
—
—
0
0
14
78
1.81
1.21
2.0
1.2
—
—
—
0
0
19
117
1.64
1.18
1.3
1.1
—
—
—
0
0
63
491
1.30
1.18
2.8
2.4
—
—
—
0
0
5
20
2.51
1.15
1.0
1.0
—
—
—
0
0
26
175
1.50
1.13
1.2
1.4
140.00
268.18
miu/ml
—
7
76
34
242
1.42
1.13
3.0
2.2
127.63
125.84
g/l
0.13
27
188
18
112
1.62
1.09
1.4
1.4
21559.38
28078.50
e6/l
—
8
62
14
81
1.74
1.09
1.4
1.3
0.23
0.45
g/l
—
7
61
14
81
1.74
1.09
1.4
1.3
5.66
7.23
g/l
—
7
60
14
81
1.74
1.09
1.4
1.3
2.35
2.77
g/l
—
7
62
21
136
1.56
1.09
3.0
2.7
—
—
—
0
0
125
1065
1.20
1.09
3.4
4.2
19.81
19.39
ug/l
0.01
100
898
10
52
1.93
1.06
2.8
2.9
—
—
—
0
0
7
33
2.13
1.05
1.9
2.3
36.43
39.52
g/l
—
7
33
14
82
1.72
1.05
1.4
1.3
—
—
—
0
0
15
90
1.68
1.04
1.1
1.1
0.46
0.65
u/ml
—
8
41
700
6727
1.13
1.04
32.8
22.3
13.93
13.79
%
1.74
689
6635
9
46
1.96
1.03
1.3
1.5
11.44
23.84
umol/l
—
9
38
5
22
2.28
1.03
2.6
2.6
3.00
6.36
ug/l
—
5
22
56
439
1.29
1.03
2.2
2.2
—
—
—
0
0
9
47
1.92
1.02
2.0
2.0
446.89
630.97
e6/l
—
9
38
14
83
1.70
1.01
1.9
1.9
—
—
—
0
0
69
557
1.26
1.01
1.3
1.3
—
—
—
0
0
7
36
1.95
0.97
1.7
1.9
25.71
30.03
umol/l
—
7
31
0
31
0.00
0.96
0.0
3.5
—
29.26
—
0
21
0
31
0.00
0.96
0.0
1.7
—
0.00
—
0
31
43
329
1.32
0.95
1.6
1.6
0.26
0.33
mg/l
0.46
19
146
61
491
1.26
0.93
1.3
1.2
149.28
142.36
u/ml
0.05
25
184
83
695
1.21
0.89
3.2
3.0
5.92
6.08
ph
0.94
57
491
18
119
1.52
0.88
2.3
1.8
91.36
89.39
%
1.18
18
119
13
81
1.61
0.81
1.0
1.2
—
—
—
0
0
19
130
1.47
0.81
1.4
1.4
1266.45
1576.68
e6/l
0.24
11
87
0
24
0.00
0.79
0.0
1.5
—
25.07
—
0
14
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
16
106
1.52
0.79
3.6
2.4
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
137.75
—
0
20
14
91
1.55
0.75
1.1
1.1
0.07
0.64
u/ml
—
8
49
18
254
0.70
0.74
1.6
1.7
—
—
—
0
0
91
788
1.17
0.71
1.6
1.5
—
—
—
0
0
35
442
0.78
0.70
1.9
1.8
3.30
3.49
mmol/l
0.34
23
341
77
659
1.18
0.69
1.4
1.2
—
—
—
0
0
5
28
1.79
0.66
3.0
2.3
2.48
2.04
umol/l
—
5
21
13
86
1.52
0.66
3.3
1.3
—
—
—
0
0
16
111
1.45
0.66
1.1
1.2
0.37
1.47
u/ml
—
10
67
7
44
1.59
0.65
3.3
1.6
—
—
—
0
0
15
104
1.45
0.62
1.4
1.2
—
—
—
0
0
11
71
1.56
0.62
1.4
1.3
—
—
—
0
0
16
113
1.42
0.61
1.6
1.4
—
—
—
0
0
18
133
1.36
0.55
1.9
1.7
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
169.17
176.19
iu/ml
—
6
38
26
205
1.28
0.53
1.4
1.3
—
—
—
0
0
9
64
1.41
0.51
3.6
2.7
15.66
15.93
%
—
9
64
15
110
1.37
0.49
1.5
1.4
—
—
—
0
0
10
69
1.45
0.44
1.3
1.1
93.90
103.87
pmol/l
—
10
69
5
31
1.62
0.43
1.0
1.9
—
—
—
0
0
8
56
1.43
0.42
2.6
1.8
—
—
—
0
0
8
56
1.43
0.42
1.4
1.6
147.63
81.46
umol/l
—
8
56
5
32
1.57
0.42
1.4
1.8
—
—
—
0
0
15
195
0.77
0.42
1.4
1.2
—
—
—
0
0
34
286
1.20
0.42
3.7
3.5
0.75
0.80
nmol/l
0.40
26
237
0
15
0.00
0.41
0.0
1.5
—
56.80
—
0
15
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
30
253
1.19
0.37
1.1
1.1
—
—
—
0
0
181
1707
1.07
0.36
3.7
3.4
0.76
0.80
ug/l
0.26
123
1143
31
263
1.18
0.36
4.1
3.2
1.78
1.57
mmol/l
0.51
31
257
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
10
74
1.35
0.32
1.3
1.3
—
—
—
0
0
24
202
1.19
0.31
2.7
3.4
165.13
1915.89
u/ml
0.78
24
190
7
57
1.23
0.29
1.6
1.2
162.00
138.76
nmol/l
—
7
57
14
112
1.25
0.28
1.7
1.7
—
—
—
0
0
9
117
0.77
0.27
1.7
5.6
312.44
358.86
umol/l
—
9
108
54
594
0.90
0.27
1.2
1.5
—
—
—
0
0
29
332
0.87
0.27
1.1
1.1
—
—
—
0
0
9
73
1.23
0.25
4.9
2.5
19.44
36.20
mg/l
—
9
51
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
8.36
—
0
5
12
98
1.23
0.21
1.5
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
219.17
—
0
6
22
192
1.15
0.21
2.6
4.0
13.06
27.59
mg/l
3.41
15
141
0
14
0.00
0.20
0.0
1.0
—
0.03
—
0
14
0
14
0.00
0.20
0.0
1.0
—
0.50
—
0
7
7
62
1.13
0.17
1.3
1.1
—
—
—
0
0
5
66
0.76
0.17
2.0
2.4
—
—
—
0
0
24
217
1.11
0.14
3.2
3.4
7.75
7.48
mmol/l
0.14
24
212
13
112
1.16
0.14
1.8
2.6
—
—
—
0
0
10
84
1.19
0.14
1.0
1.1
—
—
—
0
0
12
104
1.16
0.12
1.3
1.3
—
—
—
0
0
283
2781
1.02
0.11
3.9
3.3
—
—
—
0
0
5
60
0.83
0.08
1.6
1.6
—
—
—
0
0
18
195
0.92
0.08
1.7
1.5
—
—
—
0
0
7
66
1.06
0.08
1.3
1.1
—
—
—
0
0
19
176
1.08
0.07
1.6
1.5
—
—
—
0
0
9
85
1.06
0.07
1.0
1.1
—
—
—
0
0
13
142
0.91
0.06
1.8
1.5
—
—
—
0
0
22
207
1.06
0.06
1.0
1.1
—
—
—
0
0
12
131
0.92
0.05
1.8
1.5
—
—
—
0
0
23
239
0.96
0.02
5.7
4.9
—
—
—
0
0
22
216
1.02
0.00
1.0
1.2
—
—
—
0
0
40
404
0.99
0.00
3.5
3.3
615.43
3739.91
u/ml
0.69
32
354
11
108
1.02
0.00
1.1
1.1
—
—
—
0
0
11
108
1.02
0.00
1.1
1.1
—
—
—
0
0
19
193
0.98
0.00
1.6
1.4
—
—
—
0
0
19
195
0.97
0.00
1.6
1.4
—
—
—
0
0
19
195
0.97
0.00
1.6
1.5
—
—
—
0
0
9
99
0.91
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
0.32
—
0
6
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.05
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
9.54
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.0
—
—
—
0
0
8
88
0.91
-0.00
1.1
1.6
—
—
—
0
0
7
71
0.99
-0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_RETINAHAEMORR and mortality.

Females

Parameter HR [95% CI] p-value
H7_RETINAHAEMORR 0.987 [0.87, 1.12] 0.838
Birth year 0.998 [0.99, 1.01] 0.6

During the follow-up period (1.1.1998 — 31.12.2019), 1022 out of 3021 females with H7_RETINAHAEMORR died.

Males

Parameter HR [95% CI] p-value
H7_RETINAHAEMORR 1.254 [1.05, 1.49] 0.011
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 664 out of 2055 males with H7_RETINAHAEMORR died.

Mortality risk

Mortality risk for people of age

years, who have H7_RETINAHAEMORR.

N-year risk Females Males
1 0.073% 0.242%
5 0.625% 1.341%
10 1.745% 3.327%
15 3.176% 6.081%
20 5.491% 10.27%

Relationships between endpoints

↥

Index endpoint: H7_RETINAHAEMORR – Retinal haemorrhage

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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