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Congenital musculoskeletal deformities of head, face, spine and chest, including avohilmo

Endpoint Browser PheWeb

Q17_CONGEN_MUSCULOS_DEFORMITI_HEAD_FACE_SPINE_CHEST_WIDE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — Q67
  • Hospital discharge: ICD-10 — Q67
  • Cause of death: ICD-10 — Q67

3 out of 7 registries used, show all original rules.

555

4. Check minimum number of events

None

555

5. Include endpoints

None

555

6. Filter based on genotype QC (FinnGen only)

505

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13
Parent code in ICD-10
Q6[5-9]|Q7
Name in latin
Deformitates musculosceletales congenitae capitis, faciei, columnae vertebralis et thoracis

Similar endpoints

↥

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 505 225 280
Unadjusted period prevalence (%) 0.11 0.08 0.13
Median age at first event (years) 23.00 29.20 18.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
534
Matched controls
5340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q67.6
ICD-10 Finland
Pectus excavatum
+∞
251.6
221
*
Q67.7
ICD-10 Finland
Pectus carinatum
+∞
67.1
63
*
GAF10
NOMESCO Finland
Removal of prosthetic material after correction of malformation of chest wall
+∞
66.0
62
*
GAF03
NOMESCO Finland
Correction of pectus excavatum
+∞
66.0
62
*
DJD20
NOMESCO Finland
Plastic repair of septum of nose
11.1
64.8
73
75
Q67.48
ICD-10 Finland
Other specified congenital deformity of skull, face or jaw
+∞
62.8
59
*
Q67.4
ICD-10 Finland
Other congenital deformities of skull, face and jaw
+∞
59.5
56
*
Q67.0
ICD-10 Finland
Facial asymmetry
+∞
54.1
51
*
Q67.5
ICD-10 Finland
Congenital deformity of spine
+∞
36.9
35
*
Q67.3
ICD-10 Finland
Plagiocephaly
+∞
30.5
29
*
Q67.40
ICD-10 Finland
Other congenital deformities of skull, face and jaw
+∞
26.3
25
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
22.3
216
1144
Q67.8
ICD-10 Finland
Other congenital deformities of chest
+∞
22.0
21
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
21.2
173
842
Z31.5
ICD-10 Finland
Genetic counselling
3.9
20.7
65
182
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
8.6
20.7
27
33
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.3
20.3
42
84
ZXE20
NOMESCO Finland
More than three and less than five hours
3.0
17.1
82
300
ZXE00
NOMESCO Finland
One hour or less
2.1
15.8
222
1332
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
15.8
95
393
AA6AD
NOMESCO Finland
Cranial bones CT examination
164.6
15.6
16
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
15.6
67
230
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
15.3
182
1022
7548A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Other specified nonteratogenic anomalies[PECTUS EXCAVATUM]
+∞
14.6
14
*
75630
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Pectus excavatum
+∞
14.6
14
*
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
6.2
14.4
25
42
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
12.7
221
1408
5853
FHL
Anterior thoracoplasty (funnel breast, chicken breast)
+∞
12.5
12
*
ZZG00
NOMESCO Finland
Graft of cartilage
133.0
12.5
13
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
11.7
119
620
DLD20
NOMESCO Finland
Rhinoplasty
28.7
10.8
14
5
GAF96
NOMESCO Finland
Other correction of malformation of chest wall
+∞
10.4
10
*
Q67.2
ICD-10 Finland
Dolichocephaly
+∞
10.4
10
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
13.5
10.2
17
13
M41.9
ICD-10 Finland
Scoliosis, unspecified
8.7
10.1
21
25
K07.10
ICD-10 Finland
Asymmetry of jaw
13.7
9.7
16
12
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
101.8
9.4
10
*
GAD00
NOMESCO Finland
Thoracoplasty without plombage
+∞
9.4
9
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.2
9.2
89
452
K22
ICPC
Risk factor cardiovascular disease
3.7
9.1
29
82
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
12.8
8.9
15
12
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
8.7
118
676
Q17.2
ICD-10 Finland
Microtia
50.8
8.7
10
*
EEC05
NOMESCO Finland
Le Fort I osteotomy
16.6
8.6
13
8
J34.2
ICD-10 Finland
Deviated nasal septum
3.0
8.5
38
133
5859
FHL
Other operations in this group (eg removal of fixation plate)
+∞
8.4
8
*
M41.4
ICD-10 Finland
Neuromuscular scoliosis
33.9
8.1
10
*
Z50.1
ICD-10 Finland
Other physical therapy
3.5
8.0
27
79
Q87.4
ICD-10 Finland
Marfan syndrome
45.7
7.7
9
*
L04
ICPC
Chest symptom/complaint
2.6
7.6
46
189
N02AX02
ATC
tramadol; systemic, rectal
1.7
7.5
163
1076
R4110
NOMESCO Finland
Physiotherapy
1.8
7.3
133
833
Q75.00
ICD-10 Finland
Coronary craniosynostosis
+∞
7.3
7
*
-69
ICPC
Other reason for encounter NEC
3.7
7.2
23
65
WX002
NOMESCO Finland
Sedation and analgesia
2.0
7.1
78
414
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
7.1
52
235
R01AD05
ATC
budesonide; nasal
2.8
7.0
36
136
R06.0
ICD-10 Finland
Dyspnoea
1.8
7.0
114
691
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
6.9
218
1582
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.5
6.8
45
193
WX402
NOMESCO Finland
General anaesthesia
1.8
6.8
121
751
Q16.1
ICD-10 Finland
Congenital absence, atresia and stricture of auditory canal (external)
40.6
6.8
8
*
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
17.0
6.8
10
6
R01BA52
ATC
pseudoephedrine, combinations; oral
1.9
6.7
97
567
Q87.03
ICD-10 Finland
Syndrome Goldenhar
70.7
6.4
7
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
6.4
104
629
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
9.4
6.3
12
13
EB1MA
NOMESCO Finland
Cephalometry with X-ray
2.3
6.3
46
207
AAK30
NOMESCO Finland
Craniofacial reconstruction in congenital malformations
+∞
6.3
6
*
XF404
NOMESCO Finland
Ambulatory ECG
2.4
6.1
40
171
J31.0
ICD-10 Finland
Chronic rhinitis
2.2
6.1
53
257

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
208
1471
1.68
7.45
11.3
10.1
1.20
1.16
inr
0.62
183
1228
304
2373
1.65
7.37
4.7
5.9
6.15
6.38
mmol/l
1.48
282
2198
198
1386
1.68
7.35
6.3
7.7
—
—
—
0
0
163
1137
1.62
5.90
4.0
3.4
0.13
0.26
e6/l
1.34
124
818
180
1303
1.58
5.52
4.2
3.5
13.21
102.91
e6/l
1.08
145
975
66
365
1.92
5.33
5.6
10.4
7.42
7.41
ph
0.62
34
188
65
359
1.92
5.27
5.6
10.5
1.46
0.47
mmol/l
1.25
56
301
126
867
1.59
4.70
3.6
2.9
6.62
5.19
e6/l
0.39
120
786
463
4212
1.75
4.62
14.5
14.1
139.77
139.67
mmol/l
0.55
455
4121
463
4217
1.74
4.53
14.6
14.2
3.93
3.94
mmol/l
0.67
455
4109
83
526
1.68
4.27
2.0
1.7
—
—
—
0
0
494
4605
1.97
4.23
16.1
14.6
71.43
72.32
umol/l
0.44
489
4551
53
297
1.87
4.14
3.0
2.0
6.21
6.23
ph
0.05
43
192
55
324
1.78
3.67
2.7
1.9
0.00
0.00
estimate
—
10
85
197
1555
1.42
3.65
4.8
4.2
52.66
76.04
e6/l
0.30
145
1034
31
151
2.12
3.59
1.9
1.6
—
—
—
0
0
98
680
1.54
3.47
3.2
3.3
2.82
2.13
e6/l
0.28
55
333
96
673
1.52
3.24
5.1
3.4
355.70
580.85
ng/l
0.44
66
428
74
500
1.56
2.95
5.4
8.6
105.49
104.84
mmol/l
0.63
74
500
272
2339
1.33
2.74
7.3
8.3
31.60
31.09
%
0.31
261
2260
321
2832
1.33
2.69
4.9
4.2
—
3.36
—
0
7
228
1925
1.32
2.56
6.3
8.7
1.21
1.22
mmol/l
0.40
202
1707
285
2485
1.31
2.53
7.6
8.2
2.00
2.05
e9/l
0.35
260
2181
476
4501
1.53
2.44
14.5
12.7
24.85
21.84
mg/l
1.15
384
3477
265
2299
1.30
2.39
7.1
8.2
53.39
54.23
%
0.58
254
2226
156
1257
1.34
2.39
2.2
2.6
—
—
—
0
0
76
546
1.46
2.29
3.2
3.1
4.07
5.22
e9/l
0.86
65
492
21
106
2.02
2.28
2.1
1.9
3.75
3.97
ug/l
0.03
21
99
283
2487
1.29
2.28
7.9
8.7
0.21
0.19
e9/l
0.55
257
2161
518
5021
2.06
2.20
20.8
19.3
255.61
256.12
e9/l
0.07
507
4918
63
440
1.49
2.19
1.3
1.5
—
—
—
0
0
275
2416
1.29
2.19
7.7
8.2
0.55
0.56
e9/l
0.34
246
2063
518
5023
2.04
2.16
20.7
19.2
89.08
89.08
fl
0.00
513
4986
518
5025
2.03
2.13
20.8
19.2
4.67
4.66
e12/l
0.28
508
4916
274
2414
1.28
2.10
7.7
8.2
0.04
0.04
e9/l
0.31
245
2059
191
1610
1.29
2.08
5.4
6.0
38.02
37.42
g/l
0.76
179
1536
192
1621
1.29
2.06
6.5
8.5
—
—
—
0
0
518
5029
2.00
2.05
21.0
19.4
138.73
138.62
g/l
0.07
513
4990
255
2231
1.27
2.05
7.6
8.5
0.73
0.68
%
0.82
243
2129
256
2241
1.27
2.05
7.5
8.4
3.22
2.95
%
0.90
245
2141
205
1749
1.28
2.01
6.4
8.8
1.21
1.22
mmol/l
0.59
192
1641
131
1055
1.32
1.99
3.0
4.0
7.38
7.39
ph
1.43
92
737
66
476
1.44
1.96
1.1
1.2
—
—
—
0
0
256
2252
1.26
1.93
7.6
8.5
8.71
8.62
%
0.23
245
2157
517
5025
1.91
1.90
20.7
19.2
29.84
29.91
pg
0.44
512
4987
517
5025
1.91
1.90
21.2
19.8
41.16
42.07
%
0.49
512
4983
249
2187
1.26
1.90
9.3
11.6
0.00
0.00
e9/l
0.55
208
1723
517
5026
1.90
1.88
20.9
19.3
6.68
6.67
e9/l
0.04
507
4912
484
4634
1.47
1.87
12.0
10.5
—
—
—
0
0
482
4612
1.46
1.86
10.9
10.5
26.13
28.67
u/l
2.50
473
4508
112
891
1.33
1.85
2.2
2.5
0.87
1.04
mg/l
0.42
76
652
66
485
1.41
1.78
1.4
1.4
—
—
—
0
0
42
283
1.53
1.75
1.9
1.9
17.05
17.05
iu/l
0.00
31
218
122
992
1.30
1.72
2.9
2.6
—
—
—
0
0
5
13
3.87
1.72
1.0
2.8
—
—
—
0
0
330
3017
1.25
1.68
7.5
7.8
85.41
85.33
u/l
0.01
319
2875
27
165
1.67
1.68
3.8
7.2
—
—
—
0
0
251
2241
1.23
1.56
4.0
3.6
0.00
0.00
estimate
-0.00
52
427
115
940
1.28
1.55
4.5
4.3
—
—
—
0
0
51
372
1.41
1.46
1.6
1.4
652.85
289.13
u/ml
0.28
51
345
246
2202
1.22
1.46
3.9
3.5
0.00
0.00
estimate
-0.00
51
457
208
1831
1.22
1.46
2.6
2.9
—
—
estimate
—
0
0
34
491
0.67
1.45
1.6
1.6
3.42
3.39
mmol/l
0.06
26
325
248
2223
1.22
1.45
3.9
3.6
0.02
0.00
estimate
0.49
52
448
293
2673
1.21
1.42
10.0
11.1
3.79
3.85
e9/l
0.26
267
2288
52
383
1.40
1.42
8.6
11.3
6.86
6.82
mmol/l
0.02
52
375
25
158
1.61
1.40
1.8
2.3
—
—
—
0
0
11
53
2.10
1.39
1.3
1.4
179.86
210.33
pmol/l
0.32
11
53
0
38
0.00
1.35
0.0
1.1
—
—
—
0
0
67
520
1.33
1.33
5.5
8.5
2.39
1.26
mmol/l
2.36
61
430
56
423
1.36
1.32
5.8
6.9
7.41
7.41
ph
0.07
46
342
9
172
0.52
1.31
1.2
1.5
—
—
—
0
0
91
739
1.28
1.30
1.3
1.3
35.08
28.59
iu/ml
0.11
26
200
8
34
2.37
1.29
1.9
2.6
4.01
4.00
mmol/l
—
8
34
8
34
2.37
1.29
1.9
2.6
107.13
105.79
mmol/l
—
8
34
8
34
2.37
1.29
1.9
2.6
1.20
1.18
mmol/l
—
8
34
8
35
2.30
1.27
1.3
1.1
—
—
—
0
0
6
25
2.42
1.24
1.7
2.3
—
—
—
0
0
153
1749
0.82
1.22
2.5
2.5
—
—
—
0
0
204
1823
1.19
1.18
3.3
3.3
6.25
6.22
ph
0.17
112
1016
14
79
1.79
1.18
1.4
3.4
—
—
—
0
0
0
35
0.00
1.15
0.0
1.1
—
716.67
—
0
6
21
135
1.58
1.13
1.8
2.3
2.12
4.96
iu/l
—
10
61
68
543
1.29
1.12
5.5
8.3
7.37
7.38
ph
0.88
42
336
128
1101
1.21
1.11
6.3
5.1
—
—
—
0
0
7
31
2.27
1.10
1.0
1.2
144.14
110.74
pmol/l
—
7
31
29
205
1.44
1.03
2.8
7.7
0.80
0.61
%
1.92
29
205
79
653
1.25
1.00
1.5
1.4
447.27
449.67
titre
0.01
11
120
9
159
0.56
1.00
1.2
1.4
—
—
—
0
0
43
329
1.33
0.98
3.4
2.6
3307.33
4708.04
u/l
0.23
16
145
137
1201
1.19
0.97
3.9
3.2
2.36
2.36
mmol/l
0.30
125
1117
9
50
1.81
0.97
1.4
1.5
0.49
0.48
e9/l
—
9
50
134
1173
1.19
0.96
2.2
2.8
50.94
59.69
u/l
1.36
119
1105
28
384
0.71
0.95
1.6
1.5
—
—
—
0
0
45
349
1.32
0.94
5.7
6.9
—
—
—
0
0
6
27
2.24
0.93
1.2
2.4
13.00
338.92
ug/l
—
6
22
36
270
1.36
0.93
2.0
2.0
5.95
7.02
u/l
0.28
25
202
99
1151
0.83
0.93
1.6
1.7
—
—
—
0
0
34
253
1.37
0.93
4.7
4.8
3.10
51.13
ug/l
0.83
24
199
32
236
1.38
0.92
4.4
7.9
136.00
132.07
g/l
0.44
32
228
31
228
1.38
0.91
2.4
4.8
20.87
21.42
s
0.38
31
212
13
206
0.62
0.90
1.8
1.6
188.00
209.15
u/ml
—
8
105
37
282
1.34
0.88
1.3
1.2
—
—
—
0
0
8
43
1.87
0.87
1.0
1.3
—
—
—
0
0
12
72
1.68
0.85
7.9
4.3
3.29
3.89
e9/l
0.78
12
72
6
113
0.53
0.84
1.8
2.2
8.72
10.53
mg/l
—
6
108
11
65
1.71
0.83
1.5
1.3
2.62
2.42
g/l
—
6
51
11
65
1.71
0.83
1.5
1.3
7.20
6.33
g/l
—
6
51
11
65
1.71
0.83
1.5
1.3
0.29
0.34
g/l
—
6
50
11
65
1.71
0.83
1.5
1.3
—
—
—
0
0
8
46
1.75
0.83
1.1
1.0
—
—
—
0
0
163
1471
1.16
0.80
1.7
1.8
100.84
97.86
pmol/l
0.24
85
770
121
1067
1.17
0.80
3.6
3.3
1.02
1.02
kg/l
0.26
80
675
89
765
1.20
0.79
3.2
3.0
607.70
559.52
mosm/kgh2o
0.60
81
677
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
0.08
—
0
5
58
478
1.24
0.78
8.0
10.7
—
—
—
0
0
0
27
0.00
0.77
0.0
2.6
—
86.31
—
0
13
11
173
0.63
0.76
1.4
1.6
—
—
—
0
0
80
684
1.20
0.76
1.3
1.3
10.58
7.82
u/ml
0.17
32
268
13
85
1.54
0.69
4.6
3.0
1.41
1.35
mmol/l
0.17
13
80
35
439
0.78
0.69
1.7
1.8
—
—
—
0
0
32
405
0.78
0.68
1.3
1.6
1054.72
916.42
mu/l
0.27
27
360
138
1246
1.15
0.67
2.9
3.1
17.13
29.99
ng/l
1.99
79
714
31
241
1.30
0.67
1.5
3.3
67.72
66.19
g/l
0.49
31
231
7
43
1.64
0.67
5.6
6.0
—
—
—
0
0
19
259
0.72
0.66
1.2
1.4
241.81
244.47
miu/ml
—
7
136
18
128
1.42
0.66
2.3
2.1
299.52
286.42
ug/l
0.04
18
121
120
1334
0.87
0.66
1.8
1.6
1.86
2.04
g/l
0.87
70
796
49
405
1.23
0.66
1.9
2.5
28.45
32.44
u/l
0.87
42
337
11
164
0.66
0.62
3.5
1.6
—
—
—
0
0
25
191
1.32
0.62
2.2
1.7
2.89
4.61
iu/ml
—
8
39
58
493
1.20
0.60
2.6
2.7
0.74
0.69
ug/l
0.15
33
268
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.4
—
0.00
—
0
20
53
623
0.83
0.59
2.2
1.6
443.98
33394281.71
pmol/l
0.76
48
551
20
149
1.36
0.58
1.2
1.2
—
—
—
0
0
17
124
1.38
0.56
1.0
1.4
—
—
—
0
0
8
124
0.64
0.55
1.4
1.2
—
—
—
0
0
65
564
1.17
0.55
2.4
2.1
—
—
—
0
0
6
38
1.59
0.54
56.3
29.3
130.50
144.97
ug/l
—
6
32
303
3162
0.90
0.54
2.9
3.6
32.28
38.63
u/l
2.33
290
3046
154
1421
1.12
0.54
1.5
1.6
—
—
—
0
0
83
930
0.87
0.52
1.5
1.5
20.31
19.93
nmol/l
0.10
74
815
46
389
1.20
0.52
2.2
2.6
—
—
—
0
0
28
224
1.26
0.52
1.8
1.9
37.71
36.53
nmol/l
0.12
28
217
6
40
1.51
0.51
1.2
1.2
—
—
—
0
0
121
1322
0.89
0.51
3.8
3.6
8.70
8.77
mmol/l
0.04
108
1185
352
3397
1.11
0.50
3.9
4.1
14.75
14.68
pmol/l
0.21
330
3128
21
163
1.30
0.49
1.6
2.3
—
—
—
0
0
13
93
1.41
0.48
3.3
2.5
—
—
—
0
0
7
47
1.50
0.47
1.1
1.1
—
—
—
0
0
10
68
1.48
0.47
4.9
4.4
5.45
7.62
pmol/l
—
10
68
7
48
1.46
0.47
1.6
1.5
—
—
—
0
0
34
283
1.22
0.46
3.7
4.0
7.41
7.34
ph
1.38
24
208
5
81
0.61
0.46
2.0
2.6
—
28.06
—
0
7
7
50
1.41
0.45
1.3
1.2
—
—
—
0
0
393
4029
0.91
0.43
4.5
4.5
2.67
2.75
mmol/l
1.13
377
3823
178
1677
1.09
0.41
3.7
3.3
0.00
0.01
estimate
0.69
40
395
0
15
0.00
0.41
0.0
2.4
—
117.60
—
0
15
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
7.1
—
—
—
0
0
15
114
1.32
0.41
1.6
1.4
376.56
309.10
ug/g
—
9
62
407
3974
1.10
0.41
4.7
4.9
1.82
1.84
mu/l
0.13
386
3736
0
17
0.00
0.40
0.0
1.2
—
379.17
—
0
6
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
3.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
73
807
0.89
0.39
1.6
1.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
83.68
—
0
14
12
159
0.75
0.39
1.2
1.2
—
—
—
0
0
12
159
0.75
0.39
1.2
1.2
—
—
—
0
0
5
36
1.39
0.38
1.6
1.9
—
—
—
0
0
39
337
1.17
0.37
5.7
5.4
0.67
0.68
%
—
9
101
86
939
0.90
0.37
4.4
4.3
5.61
28.54
mg/mmol
0.71
54
640
21
254
0.82
0.34
1.1
1.1
—
—
—
0
0
120
1282
0.92
0.34
3.1
2.9
0.00
0.00
estimate
-0.00
37
371
33
381
0.86
0.33
1.3
1.3
38.15
151.53
u/ml
4.56
12
139
29
247
1.18
0.33
2.2
4.0
1.24
1.23
mmol/l
0.68
24
219
46
408
1.14
0.33
4.0
8.5
24.78
23.73
mmol/l
1.88
46
408
10
74
1.36
0.32
4.8
4.4
—
—
—
0
0
93
861
1.10
0.32
2.4
3.3
324.61
334.70
umol/l
0.51
85
786
393
4010
0.92
0.32
4.3
4.1
4.50
4.58
mmol/l
1.19
379
3826
18
219
0.82
0.32
1.1
1.1
1.41
1.49
g/l
0.63
18
219
85
918
0.91
0.31
3.6
3.7
26.70
73.32
mg/l
3.04
52
642
391
3987
0.93
0.30
4.2
4.0
1.41
1.41
mmol/l
0.02
376
3787
381
3732
1.07
0.29
4.0
3.8
5.60
5.68
mmol/l
0.66
361
3462
8
62
1.29
0.28
1.5
2.9
—
—
—
0
0
31
271
1.15
0.27
1.1
1.3
—
—
—
0
0
9
116
0.77
0.27
1.2
1.2
—
—
—
0
0
371
3635
1.07
0.27
4.9
4.9
37.16
37.46
mmol/mol
0.28
357
3471
65
599
1.10
0.26
3.0
2.4
2.42
2.43
mmol/l
0.08
58
531
5
75
0.66
0.26
1.0
1.3
—
—
—
0
0
50
548
0.90
0.25
1.3
1.2
—
—
—
0
0
39
350
1.12
0.25
6.7
6.1
0.00
0.11
%
—
8
90
160
1669
0.94
0.24
1.9
1.9
1.34
1.34
mmol/l
0.02
142
1468
114
1080
1.07
0.24
2.4
2.7
2.80
2.70
mg/l
0.14
99
963
49
447
1.11
0.24
1.9
2.0
—
—
—
0
0
19
222
0.85
0.24
1.2
1.1
0.83
0.89
g/l
0.76
19
222
19
222
0.85
0.24
1.8
1.9
—
—
—
0
0
13
106
1.23
0.23
1.5
1.9
1.03
0.79
g/l
—
8
89
5
39
1.28
0.23
1.8
5.1
20.10
20.61
ug/l
—
5
39
192
1853
1.06
0.23
3.0
2.8
74.18
71.38
nmol/l
0.90
182
1730
33
295
1.13
0.22
7.7
5.6
61.29
73.26
ng/l
0.77
33
281
7
93
0.75
0.22
1.4
1.7
12.86
38.71
ng/l
—
7
93
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
9.67
—
0
11
0
10
0.00
0.21
0.0
1.0
—
165.10
—
0
10
0
10
0.00
0.21
0.0
1.3
—
51.60
—
0
10
8
103
0.77
0.21
2.4
5.1
39.13
40.18
umol/l
—
8
98
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
4.6
5.1
1.93
1.93
ug/l
—
5
43
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
3.00
—
0
13
0
13
0.00
0.21
0.0
1.3
—
17.40
—
0
5
0
13
0.00
0.21
0.0
26.8
—
0.47
—
0
13
58
539
1.09
0.20
1.9
1.9
—
—
—
0
0
6
48
1.25
0.20
8.0
1.9
10.05
10.15
mmol/l
—
6
48
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
89
842
1.07
0.20
4.4
4.5
1.54
2.03
ug/l
0.60
82
758
27
241
1.13
0.19
1.2
1.1
—
—
—
0
0
12
143
0.84
0.19
1.1
1.1
—
—
—
0
0
14
164
0.85
0.18
1.4
1.3
—
—
—
0
0
36
329
1.10
0.18
4.1
3.5
—
—
—
0
0
48
446
1.08
0.17
2.0
1.6
1009.35
1170.65
nmol/l
0.60
28
353
20
226
0.88
0.17
2.8
2.6
—
—
—
0
0
31
282
1.11
0.17
1.2
1.5
—
—
—
0
0
37
340
1.09
0.17
6.9
5.7
0.00
0.14
%
—
7
93
8
71
1.13
0.16
2.6
4.0
43.50
36.80
%
—
8
71
15
130
1.16
0.16
6.6
3.3
53.40
55.60
%
0.38
15
130
6
80
0.75
0.15
1.7
1.9
—
—
—
0
0
8
98
0.81
0.14
1.0
1.1
—
—
—
0
0
47
498
0.94
0.13
2.2
2.2
386.60
371.27
nmol/l
0.19
42
470
229
2249
1.03
0.12
3.1
3.3
82.63
89.20
ug/l
0.39
217
2143
30
322
0.93
0.11
2.4
5.0
77.74
70.86
e9/l
0.35
19
218
30
279
1.08
0.11
1.4
1.6
0.08
0.29
mg/l
6.92
14
123
38
358
1.07
0.10
6.8
5.6
0.14
0.96
%
—
7
111
32
300
1.07
0.10
1.2
1.2
—
32.82
—
0
17
60
577
1.04
0.09
1.9
1.8
—
—
—
0
0
60
577
1.04
0.09
1.9
1.9
—
—
—
0
0
204
2008
1.03
0.09
5.4
7.3
11.88
12.51
umol/l
0.20
191
1913
6
55
1.09
0.09
1.2
1.2
—
—
—
0
0
377
3740
1.03
0.08
3.6
3.5
1.20
1.23
mmol/l
0.42
359
3538
62
598
1.04
0.08
1.3
1.3
—
—
—
0
0
60
579
1.04
0.08
1.9
1.9
—
—
—
0
0
45
431
1.05
0.08
1.3
1.2
—
—
—
0
0
81
833
0.97
0.07
3.0
3.1
96.70
124.82
ug/g
0.47
63
679
8
76
1.05
0.07
1.0
1.0
1.35
1.40
g/l
—
8
69
7
82
0.85
0.07
1.3
1.1
—
—
—
0
0
92
942
0.97
0.07
1.7
1.9
—
—
—
0
0
52
502
1.04
0.07
1.5
1.6
—
—
—
0
0
16
172
0.93
0.06
1.1
1.3
—
—
—
0
0
25
237
1.06
0.06
11.9
14.9
1.31
1.17
mg/l
0.40
25
225
17
159
1.07
0.05
1.1
1.3
—
—
—
0
0
59
576
1.03
0.04
1.9
1.9
—
—
—
0
0
14
150
0.93
0.04
1.1
1.1
0.80
0.39
u/ml
—
5
67
34
328
1.04
0.04
2.4
2.3
24.62
16.74
au/ml
—
6
33
16
170
0.94
0.04
1.1
1.1
35.66
4.22
u/ml
—
9
108
147
1484
0.99
0.03
2.0
2.2
—
—
—
0
0
15
142
1.06
0.02
1.1
2.5
3.85
3.60
mmol/l
0.58
15
135
21
218
0.96
0.02
1.0
1.2
0.59
1.98
u/ml
1.28
14
150
142
1431
0.99
0.02
1.9
1.9
—
—
—
0
0
105
1060
0.99
0.02
1.7
1.7
—
—
—
0
0
12
113
1.06
0.02
1.7
2.4
0.78
0.67
nmol/l
0.21
12
99
149
1481
1.01
0.01
1.6
1.6
3.49
2.38
u/ml
0.18
34
376
23
237
0.97
0.01
1.4
1.5
—
—
—
0
0
24
247
0.97
0.01
1.1
1.2
1.69
3.46
u/ml
0.71
13
165
15
144
1.04
0.00
1.1
1.1
3.58
8.58
eliau/ml
—
5
23
21
216
0.97
0.00
1.1
1.2
1.23
1.17
u/ml
0.03
11
139
20
195
1.03
0.00
1.2
1.2
—
—
—
0
0
12
124
0.97
0.00
1.8
2.8
—
—
—
0
0
15
153
0.98
0.00
1.1
1.1
5.45
8.22
u/ml
—
9
84
51
506
1.01
0.00
2.1
4.9
4.65
7.48
umol/l
2.10
46
436
12
122
0.98
0.00
9.0
11.2
—
—
—
0
0
16
158
1.01
0.00
2.2
1.4
1.27
1.19
g/l
0.46
16
153
53
527
1.01
0.00
1.4
1.6
—
—
—
0
0
27
272
0.99
0.00
1.4
1.6
403.76
304.16
mu/l
0.66
21
256
10
99
1.01
0.00
1.3
1.4
12.86
4.28
ug/l
—
10
91
10
101
0.99
0.00
1.1
1.1
—
—
—
0
0
116
1157
1.00
0.00
4.1
3.5
0.00
0.01
estimate
0.74
46
426
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
7.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
54
0.93
-0.00
3.8
1.9
5.94
4.74
mmol/24h
—
5
47
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
22
220
1.00
-0.00
1.1
1.2
13.61
8.17
u/ml
0.41
15
157
0
5
0.00
-0.00
0.0
1.0
—
8.52
—
0
5
0
8
0.00
-0.00
0.0
2.4
—
2.89
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.4
—
410.00
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
0.02
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
-0.00
1.4
3.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
86
0.93
-0.00
2.0
3.3
11.43
20.60
mu/l
—
8
78
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
88
0.91
-0.00
1.1
1.1
—
—
—
0
0
8
82
0.98
-0.00
1.4
1.9
—
—
—
0
0
8
82
0.98
-0.00
1.4
1.9
—
—
—
0
0
6
66
0.91
-0.00
1.5
2.2
59.67
67.14
mmol/l
—
6
56
0
5
0.00
-0.00
0.0
1.4
—
14.34
—
0
5
7
71
0.99
-0.00
1.0
1.3
—
—
—
0
0
18
180
1.00
-0.00
2.1
1.9
0.00
0.00
estimate
—
6
67
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
0.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
-0.00
1.1
1.1
—
—
—
0
0
8
82
0.98
-0.00
1.4
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.98
-0.00
1.4
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
3.3
2.1
—
—
—
0
0
5
59
0.85
-0.00
1.4
1.4
35.88
93.97
mu/l
—
5
53
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
4.9
5.2
341.05
399.86
umol/l
—
8
71
0
5
0.00
-0.00
0.0
1.0
—
271.00
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_CONGEN_MUSCULOS_DEFORMITI_HEAD_FACE_SPINE_CHEST_WIDE – Congenital musculoskeletal deformities of head, face, spine and chest, including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).