No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
229 |
4. Check minimum number of eventsNone |
229 |
5. Include endpointsNone |
229 |
6. Filter based on genotype QC (FinnGen only) |
206 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF13
Similar endpoints
↥List of similar endpoints to
Pectus excavatum, including avohilmo
based on the number of shared cases.
Similar with more cases:
- Congenital musculoskeletal deformities of head, face, spine and chest, including avohilmo
- Congenital malformations and deformations of the musculoskeletal system, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 206 | 75 | 131 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 18.56 | 21.59 | 16.83 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 221
- Matched controls
- 2210
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q67.6
ICD-10 Finland
Pectus excavatum
+∞
320.1
221
*
GAF03
NOMESCO Finland
Correction of pectus excavatum
+∞
68.3
62
*
GAF10
NOMESCO Finland
Removal of prosthetic material after correction of malformation of chest wall
+∞
67.2
61
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.2
31.6
32
28
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.1
20.6
51
123
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
15.4
102
474
75630
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Pectus excavatum
+∞
14.7
14
*
7548A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Other specified nonteratogenic anomalies[PECTUS EXCAVATUM]
+∞
14.7
14
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
12.3
73
313
5853
FHL
Anterior thoracoplasty (funnel breast, chicken breast)
+∞
11.6
11
*
Z31.5
ICD-10 Finland
Genetic counselling
4.3
11.1
31
81
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.3
11.0
50
182
GAF96
NOMESCO Finland
Other correction of malformation of chest wall
+∞
10.5
10
*
XF404
NOMESCO Finland
Ambulatory ECG
5.0
10.3
23
50
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.3
9.3
25
63
Q67.7
ICD-10 Finland
Pectus carinatum
38.4
9.1
11
*
R06.0
ICD-10 Finland
Dyspnoea
2.7
8.7
56
246
5859
FHL
Other operations in this group (eg removal of fixation plate)
+∞
8.4
8
*
GAD00
NOMESCO Finland
Thoracoplasty without plombage
+∞
8.4
8
*
L04
ICPC
Chest symptom/complaint
3.7
8.0
27
81
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
117
2.92
6.31
5.2
16.4
2.02
0.55
mmol/l
1.05
26
93
41
202
2.26
4.83
4.0
3.3
634.07
1598.33
ng/l
0.59
33
153
115
866
1.68
3.57
4.0
6.3
5.89
6.29
mmol/l
2.28
104
787
180
1544
1.89
3.39
8.6
9.4
103.28
102.00
ml/min/173m2
0.39
158
1344
202
1818
2.29
3.11
12.5
11.3
25.29
22.13
mg/l
0.68
156
1357
17
69
2.59
3.04
4.5
18.0
0.59
0.69
%
0.64
17
69
17
72
2.47
2.80
4.8
17.5
95.83
94.51
%
0.43
17
72
17
72
2.47
2.80
4.8
17.4
0.90
1.40
%
2.44
17
72
22
106
2.19
2.74
1.6
1.3
—
—
—
0
0
62
425
1.64
2.62
2.9
2.5
19.00
16.58
ng/l
0.16
34
207
26
144
1.91
2.26
1.7
1.4
83.93
451.41
u/ml
1.25
26
136
50
337
1.63
2.24
1.6
2.7
1.24
1.27
mg/l
0.02
28
236
185
1668
1.67
2.11
12.4
11.6
3.89
3.92
mmol/l
0.62
180
1622
5
10
5.09
2.08
1.8
1.8
20.10
16.45
ug/l
—
5
10
185
1672
1.65
2.04
12.2
11.6
139.94
139.72
mmol/l
0.99
180
1631
51
356
1.56
1.97
2.3
2.7
—
—
—
0
0
21
115
1.91
1.90
3.8
4.4
—
—
—
0
0
75
578
1.45
1.80
5.3
5.9
38.80
38.43
g/l
0.21
66
549
7
24
2.98
1.73
1.1
1.2
168.33
222.27
pmol/l
—
7
24
5
13
3.91
1.72
1.0
1.1
—
—
—
0
0
200
1869
1.74
1.62
9.4
9.4
25.70
31.04
u/l
4.16
195
1822
84
672
1.40
1.61
5.8
9.4
1.20
1.21
mmol/l
0.77
73
589
215
2071
2.40
1.45
18.8
16.6
250.64
255.66
e9/l
0.67
210
2030
135
1187
1.35
1.37
4.4
4.1
7.00
7.16
mm/h
0.06
130
1110
9
175
0.49
1.36
1.2
2.5
29.00
31.88
u/l
—
9
147
215
2075
2.33
1.32
18.9
16.5
4.70
4.74
e12/l
0.73
210
2031
20
128
1.62
1.13
5.8
6.2
3.77
0.99
mmol/l
1.44
13
92
25
172
1.51
1.05
5.0
10.8
104.72
104.93
mmol/l
0.11
25
172
5
22
2.30
1.04
1.8
1.5
0.46
0.39
e9/l
—
5
22
17
108
1.62
1.00
2.1
2.9
92.22
82.02
ml/min/173m2
—
9
45
73
611
1.29
0.98
6.1
9.2
1.20
1.22
mmol/l
1.15
66
576
9
52
1.76
0.93
1.0
1.2
—
—
—
0
0
18
120
1.54
0.88
2.7
2.8
—
—
—
0
0
20
137
1.51
0.87
1.9
1.5
1162.87
1049.30
nmol/l
—
10
109
169
1581
1.29
0.86
4.2
4.5
1.71
1.81
mu/l
0.80
157
1492
5
96
0.51
0.80
1.8
1.8
—
—
—
0
0
129
1175
1.24
0.80
7.3
7.5
84.61
83.29
u/l
0.10
124
1109
0
26
0.00
0.79
0.0
2.5
—
0.00
—
0
26
0
27
0.00
0.78
0.0
2.5
—
0.00
—
0
27
152
1619
0.80
0.75
3.4
3.5
4.40
4.54
mmol/l
1.59
144
1560
52
431
1.27
0.75
2.6
3.1
0.00
0.01
estimate
0.50
21
164
5
25
2.02
0.73
1.0
1.3
—
—
—
0
0
74
641
1.23
0.73
2.6
2.7
0.00
0.01
estimate
0.50
17
153
25
189
1.36
0.68
2.8
7.7
2.88
1.30
mmol/l
1.36
25
154
82
724
1.21
0.66
2.0
1.8
—
—
—
0
0
69
599
1.22
0.66
2.1
2.5
—
—
—
0
0
152
1611
0.82
0.66
3.3
3.4
1.38
1.36
mmol/l
0.20
144
1542
21
155
1.39
0.66
3.1
2.6
262.45
5854.89
u/l
—
6
67
48
401
1.25
0.65
2.7
2.6
2.70
2.57
mg/l
0.19
41
351
7
111
0.62
0.60
2.0
1.8
—
—
—
0
0
0
22
0.00
0.59
0.0
1.8
—
—
—
0
0
94
848
1.19
0.59
2.8
3.1
0.00
0.00
estimate
-0.00
22
167
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
143
1339
1.19
0.58
3.4
3.8
14.99
14.65
pmol/l
1.09
136
1232
154
1623
0.83
0.58
3.4
3.7
2.63
2.77
mmol/l
1.50
146
1554
93
847
1.17
0.51
2.8
3.0
0.00
0.00
estimate
-0.00
22
168
53
460
1.20
0.51
2.0
2.8
54.70
65.90
u/l
0.59
44
433
10
142
0.69
0.48
1.8
1.4
—
—
—
0
0
5
84
0.59
0.46
1.4
1.3
—
—
—
0
0
5
84
0.59
0.46
3.8
5.2
93.40
93.32
%
—
5
84
113
1051
1.15
0.46
9.6
9.9
3.58
3.92
e9/l
1.29
103
902
91
835
1.15
0.45
2.8
3.0
0.00
0.00
estimate
-0.00
22
177
56
495
1.18
0.44
2.2
2.4
0.00
0.00
estimate
-0.00
17
145
5
33
1.53
0.41
1.2
1.2
—
—
—
0
0
26
312
0.81
0.41
4.2
4.7
6.17
15.79
mg/mmol
0.75
15
232
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
39
337
1.19
0.40
1.9
2.5
—
—
—
0
0
34
290
1.20
0.40
1.6
2.4
—
—
—
0
0
5
37
1.36
0.37
3.4
3.3
2.84
7.22
u/ml
—
5
37
23
190
1.23
0.36
2.6
7.8
6.37
5.84
kpa
1.51
23
185
18
145
1.26
0.35
2.3
7.9
25.58
23.79
mmol/l
1.40
18
145
94
877
1.13
0.35
3.3
3.3
72.68
75.79
ug/l
0.11
87
839
125
1313
0.89
0.34
2.5
3.6
28.33
34.90
u/l
1.35
119
1272
13
100
1.32
0.34
1.5
1.6
—
—
—
0
0
14
109
1.30
0.34
1.1
1.2
3.43
3.12
u/ml
—
5
73
21
252
0.82
0.34
1.1
1.3
1.32
6.57
u/ml
—
9
98
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
6
46
1.31
0.33
1.2
1.4
—
—
—
0
0
57
517
1.14
0.32
1.5
1.7
91.79
96.81
pmol/l
0.28
35
281
70
645
1.12
0.31
2.1
2.6
—
—
—
0
0
7
54
1.31
0.30
1.3
1.6
306.14
379.67
mg/l
—
7
54
76
708
1.11
0.28
2.9
2.9
—
—
estimate
—
0
0
23
267
0.85
0.27
1.9
3.0
1.77
0.59
e6/l
—
8
139
28
245
1.16
0.26
6.6
3.0
77.60
805.38
ng/l
0.79
16
133
9
72
1.26
0.26
3.4
6.3
1.26
1.66
%
—
9
72
25
219
1.16
0.23
1.8
1.9
—
—
—
0
0
22
252
0.86
0.23
1.7
3.0
4.86
2.32
e6/l
—
5
125
143
1473
0.92
0.21
3.4
3.3
5.39
5.61
mmol/l
2.60
134
1378
65
609
1.10
0.21
1.5
1.5
5.96
2.00
u/ml
0.37
17
150
0
11
0.00
0.21
0.0
1.4
—
2.55
—
0
11
0
11
0.00
0.21
0.0
2.1
—
1106.36
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.29
—
0
12
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
98.23
—
0
13
9
114
0.78
0.20
5.6
7.0
72.52
64.10
ng/l
—
9
105
0
14
0.00
0.20
0.0
1.4
—
9.43
—
0
14
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
30
272
1.12
0.18
1.1
1.3
13.12
23.00
iu/ml
—
6
76
20
226
0.87
0.18
1.5
1.5
—
—
—
0
0
10
120
0.83
0.17
1.4
1.4
—
—
—
0
0
8
70
1.15
0.16
2.8
1.7
—
—
—
0
0
54
510
1.08
0.15
2.6
3.6
—
—
—
0
0
144
1409
1.06
0.13
3.6
4.2
35.17
36.61
mmol/mol
2.16
139
1351
148
1508
0.94
0.12
2.7
3.1
1.08
1.23
mmol/l
2.35
137
1435
18
163
1.11
0.11
1.1
1.0
—
—
—
0
0
19
208
0.91
0.11
2.7
3.7
26.96
21.69
%
—
5
72
18
164
1.11
0.10
1.8
1.6
—
—
—
0
0
5
44
1.14
0.10
1.4
2.7
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
45
1.11
0.10
3.0
1.8
—
—
—
0
0
174
1720
1.05
0.08
3.7
3.7
—
—
—
0
0
6
58
1.04
0.08
1.0
1.2
—
—
—
0
0
8
76
1.05
0.07
1.3
1.3
—
—
—
0
0
8
91
0.87
0.07
1.4
1.6
81.11
52.12
ug/l
—
8
91
45
438
1.03
0.04
2.6
2.6
1.02
1.02
kg/l
0.65
28
265
15
159
0.94
0.03
1.3
1.3
—
—
—
0
0
43
420
1.03
0.03
1.9
3.3
0.10
0.22
e6/l
1.12
29
308
12
128
0.93
0.02
1.3
2.0
—
—
—
0
0
16
161
0.99
0.00
2.1
1.6
—
—
—
0
0
174
1744
0.99
0.00
16.5
13.8
335.73
335.87
g/l
0.08
174
1731
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
9.16
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
10
100
1.00
-0.00
1.4
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
106.00
—
0
7
0
5
0.00
-0.00
0.0
2.6
—
284.20
—
0
5
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
0.60
—
0
5
6
64
0.94
-0.00
1.7
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
30.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
186.00
—
0
5
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
49
1.02
-0.00
1.4
2.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
66.80
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
69
1.01
-0.00
1.6
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_PECTUS_EXCAVATUM_WIDE – Pectus excavatum, including avohilmo
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).