appendicitis: Acute inflammation of the vermiform appendix.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4009 |
4. Check minimum number of eventsNone |
4009 |
5. Include endpointsNone |
4009 |
6. Filter based on genotype QC (FinnGen only) |
3635 |
Control definitions (FinnGen only)
- Control exclude
- K11_APPENDIX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other appendicitis
based on the number of shared cases.
Similar with more cases:
- Appendicitis, broad definition
- Diseases of appendix
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 30807 | 15923 | 14710 |
| Only index persons | 27597 | 14579 | 13018 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.43 | 0.46 | 0.41 |
| Only index persons | 0.52 | 0.54 | 0.50 |
| Median age at first event (years) | |||
| Whole population | 26.65 | 26.67 | 26.39 |
| Only index persons | 25.39 | 25.68 | 25.07 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3635 | 2144 | 1491 |
| Unadjusted period prevalence (%) | 0.73 | 0.76 | 0.68 |
| Median age at first event (years) | 28.95 | 27.81 | 30.58 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3754
- Matched controls
- 37540
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
54199
ICD-8 Finland
Appendicitis, unqualified
+∞
307.7
1286
*
5410X
ICD-9 Finland
Appendicitis, unqualified[APPENDICITIS NUD]
+∞
307.7
659
*
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
397.5
307.7
629
19
K36
ICD-10 Finland
Other appendicitis
1908.7
307.7
334
*
JEA01
NOMESCO Finland
Laparoscopic appendectomy
99.6
307.7
770
97
6421
FHL
Appendicectomy
29.6
307.7
783
331
K37
ICD-10 Finland
Unspecified appendicitis
787.9
307.7
944
16
54200
ICD-8 Finland
Other appendicitis, Appendicitis chronica
+∞
232.8
221
*
JEA00
NOMESCO Finland
Appendectomy
6.7
141.5
233
369
54208
ICD-8 Finland
Other appendicitis
+∞
113.1
108
*
K35.1
ICD-10 Finland
Acute appendicitis with peritoneal abscess
+∞
111.0
106
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
109.9
668
2729
5428X
ICD-9 Finland
Other appendicitis[APPENDICITIS ALIA DEFINITA]
+∞
107.8
103
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
87.7
1533
9635
K35.0
ICD-10 Finland
Acute appendicitis with generalized peritonitis
+∞
82.6
79
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
66.4
422
1738
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
64.3
994
5863
P01AB01
ATC
metronidazole; oral, rectal
1.8
59.0
1564
10834
54003
ICD-8 Finland
Acute appendicitis, Cum abscessu
+∞
49.1
47
*
5420A
ICD-9 Finland
Other appendicitis[APPENDICITIS CHRONICA]
+∞
49.1
47
*
WX402
NOMESCO Finland
General anaesthesia
1.7
42.1
890
5673
54099
ICD-8 Finland
Acute appendicitis, Without mention of peritonitis
+∞
39.6
38
*
5409X
ICD-9 Finland
Acute appendicitis, Without mention of peritonitis
+∞
39.6
38
*
ZXD05
NOMESCO Finland
Urgent procedure
1.7
39.3
1041
7031
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
33.5
892
5992
WX704
NOMESCO Finland
Intubation
2.1
30.5
318
1601
N02BE01
ATC
paracetamol; systemic, rectal
1.7
26.8
3270
29918
A02BC05
ATC
esomeprazole; systemic
1.5
26.1
1424
11067
N02AX02
ATC
tramadol; systemic, rectal
1.5
25.7
1487
11676
R10.0
ICD-10 Finland
Acute abdomen
2.7
25.1
133
497
5401A
ICD-9 Finland
Acute appendicitis, With peritoneal abscess
+∞
25.0
24
*
J01DB01
ATC
cefalexin; oral
1.6
24.8
3004
27048
D88
ICPC
Appendicitis
84.0
22.7
25
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
21.7
637
4328
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
21.1
447
2804
D01
ICPC
Abdominal pain/cramps general
1.7
21.0
435
2711
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.7
20.9
115
439
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
19.9
1522
12385
54201
ICD-8 Finland
Other appendicitis, Appendicitis recidivans
+∞
19.8
19
*
K35
ICD-10 Finland
Acute appendicitis
22.7
19.0
27
12
M01AB05
ATC
diclofenac; systemic, rectal
1.4
18.9
2356
20664
UJF32
NOMESCO Finland
Coloscopy
1.4
18.2
824
6100
J01AA02
ATC
doxycycline; systemic
1.4
17.7
2754
24887
N03AX16
ATC
[U] pregabalin
1.5
17.2
753
5532
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
17.2
914
6957
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
16.9
1177
9370
JAH01
NOMESCO Finland
Laparoscopy
2.1
16.1
158
777
A02BC02
ATC
pantoprazole; systemic
1.3
16.1
2366
21002
ZXE00
NOMESCO Finland
One hour or less
1.4
15.7
1238
10022
M03BX02
ATC
tizanidine; oral
1.3
15.6
2216
19524
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
15.0
699
5183
SPAT1263
SPAT
Sampling
1.3
14.6
1309
10770
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
14.3
175
933
H02AB06
ATC
prednisolone; systemic
1.3
13.9
1564
13260
99850
ICD-8 Finland
Other complications of surgical procedures, Postoperative wound infection
5.3
13.7
27
51
M79.6
ICD-10 Finland
Pain in limb
1.3
13.6
1506
12724
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
13.6
535
3840
J01MA02
ATC
ciprofloxacin; systemic
1.3
13.5
1215
9973
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
13.4
345
2262
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.2
12.9
112
527
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
12.8
1485
12598
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
12.6
601
4462
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
12.3
3283
31087
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
12.0
2520
22964
M01AE02
ATC
naproxen; oral, rectal
1.3
12.0
1910
16812
M54.5
ICD-10 Finland
Low back pain
1.3
11.9
1235
10298
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
11.8
1775
15507
J01MA12
ATC
levofloxacin; systemic
1.4
11.7
542
4002
A02BC01
ATC
omeprazole; systemic
1.3
11.6
813
6415
5421A
ICD-9 Finland
Other appendicitis[APPENDICITIS RECIDIVANS]
+∞
11.5
11
*
R51.80
ICD-10 Finland
Headache
1.4
11.4
515
3785
R03AC02
ATC
salbutamol; inhalant
1.3
11.2
1855
16350
D06
ICPC
Abdominal pain localized other
1.6
11.2
283
1847
A02BC03
ATC
lansoprazole; oral
1.3
11.2
871
6975
A03FA02
ATC
cisapride; oral, rectal
1.7
11.1
208
1259
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
11.1
1455
12462
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
11.0
1082
8936
AA1AD
NOMESCO Finland
CT of head and brain
1.3
10.7
837
6703
D37.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Appendix
10.0
10.5
20
20
54191, ,
ICD-8 Finland
+∞
10.4
10
*
Y0599
ICD-8 Finland
Investigation of digestive system
2.8
10.3
51
186
M01AH05
ATC
etoricoxib; oral
1.3
10.0
2185
19775
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
9.8
828
6690
R06.0
ICD-10 Finland
Dyspnoea
1.3
9.6
804
6486
M01AH01
ATC
celecoxib; oral
1.4
9.6
527
3997
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
9.2
282
1921
UKC02
NOMESCO Finland
Cystoscopy
1.4
9.2
417
3061
B01AB05
ATC
enoxaparin; parenteral
1.3
9.2
925
7634
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
9.1
864
7077
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
9.1
675
5352
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
9.0
718
5750
N05BA04
ATC
oxazepam; oral
1.3
8.9
798
6487
G44.2
ICD-10 Finland
Tension-type headache
1.4
8.8
431
3205
R51
ICD-10 Finland
Headache
1.6
8.8
183
1142
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
8.7
777
6312
J01EA01
ATC
trimethoprim; systemic
1.3
8.7
748
6047
H57.1
ICD-10 Finland
Ocular pain
1.8
8.6
128
728
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
8.6
354
2554
N05BA01
ATC
diazepam; systemic, rectal
1.4
8.5
378
2763
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
8.5
165
1012
J02AC01
ATC
fluconazole; systemic
1.2
8.5
1279
11047
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
8.4
400
2962
J01MA14
ATC
moxifloxacin; systemic
1.5
8.4
262
1794
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
8.4
1746
15594
54100, ,
ICD-8 Finland
+∞
8.3
8
*
54091
ICD-8 Finland
Acute appendicitis, Gangraenosa, peritonitide non indicata
+∞
8.3
8
*
K30
ICD-10 Finland
Functional dyspepsia
1.4
8.3
352
2554
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
2.7
8.2
42
156
R50.9
ICD-10 Finland
Fever, unspecified
1.4
8.2
448
3392
N06AX21
ATC
duloxetine; oral
1.4
8.2
382
2818
WX725
NOMESCO Finland
Noninvasive ventilation
1.6
8.1
170
1064
J01FA10
ATC
azithromycin; systemic
1.2
8.1
1933
17477
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
2.8
8.1
39
141
N06AX11
ATC
mirtazapine; oral
1.2
8.0
1075
9152
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
8.0
344
2502
N06AA09
ATC
amitriptyline; systemic
1.5
8.0
266
1844
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.8
8.0
121
693
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
7.9
395
2946
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
7.9
589
4667
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
7.9
810
6688
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.4
7.8
335
2434
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
2.4
7.8
50
208
S06.0
ICD-10 Finland
Concussion
1.4
7.8
316
2275
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
1.9
7.8
87
453
XKD00
NOMESCO Finland
Uroflowmetry
1.4
7.7
379
2818
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
7.7
293
2083
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
7.6
1869
16896
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.4
7.6
310
2236
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.4
7.5
283
2008
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
7.4
822
6838
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
7.4
915
7708
UJF30
NOMESCO Finland
Ileoscopy through colon
1.4
7.4
309
2236
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
7.4
387
2909
J01DA01
ATC
[U] cefalexin
1.2
7.4
2024
18474
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
7.4
585
4672
R52.9
ICD-10 Finland
Pain, unspecified
1.4
7.4
312
2264
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
7.3
616
4958
N06AB10
ATC
escitalopram; oral
1.3
7.2
645
5228
J01FF01
ATC
clindamycin; systemic
1.3
7.2
821
6851
7231A
ICD-9 Finland
Other disorders of cervical region, Cervicalgia
3.1
7.2
29
95
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.8
7.1
100
561
A02BA04
ATC
nizatidine; systemic
1.5
7.1
195
1300
J01DA06
ATC
[U] cefuroxime
1.3
7.0
417
3200
N03AX12
ATC
[U] gabapentin; oral
1.3
7.0
471
3679
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
1.7
6.9
108
625
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
6.9
844
7099
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
6.8
406
3111
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.6
6.8
154
983
1220
FHL
Arthroscopy
1.7
6.8
111
651
Z13.5
ICD-10 Finland
Special screening examination for eye and ear disorders
3.0
6.8
29
98
K38.9
ICD-10 Finland
Disease of appendix, unspecified
40.1
6.8
8
*
T81.2
ICD-10 Finland
Accidental puncture and laceration during a procedure, not elsewhere classified
2.7
6.8
34
126
C01CA24
ATC
epinephrine; parenteral
1.5
6.7
193
1299
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.2
6.7
52
236
N05AH04
ATC
quetiapine; oral
1.3
6.7
535
4274
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.7
2283
21172
G47.3
ICD-10 Finland
Sleep apnoea
1.3
6.6
723
5997
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
2.2
6.6
51
231
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.4
6.6
324
2410
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.4
6.6
296
2171
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
1.9
6.6
80
430
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.4
6.5
245
1739
R03BA05
ATC
fluticasone; inhalant
1.3
6.5
530
4245
Z71.9
ICD-10 Finland
Counselling, unspecified
1.4
6.5
244
1734
K66.0
ICD-10 Finland
Peritoneal adhesions
3.7
6.5
20
55
J01FA06
ATC
roxithromycin; oral
1.2
6.4
1237
10875
XFE00
NOMESCO Finland
Epicardial ultrasonography
2.1
6.4
57
274
R42
ICD-10 Finland
Dizziness and giddiness
1.3
6.4
645
5301
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
6.4
556
4489
M02AA07
ATC
piroxicam; topical
1.2
6.4
1035
8952
R52.2
ICD-10 Finland
Other chronic pain
1.7
6.4
115
694
S83.2
ICD-10 Finland
Tear of meniscus, current
1.5
6.3
209
1449
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
2.0
6.3
65
330
XKD06
NOMESCO Finland
Physiologic investigation of micturition
1.9
6.3
75
400
C07AB07
ATC
bisoprolol; oral
1.2
6.3
1392
12396
54190, ,
ICD-8 Finland
+∞
6.2
6
*
K38.8
ICD-10 Finland
Other specified diseases of appendix
+∞
6.2
6
*
C10AX09
ATC
ezetimibe; oral
1.3
6.2
478
3798
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
1.7
6.2
107
638
A02BA02
ATC
ranitidine; systemic
1.3
6.2
519
4169
M01AX17
ATC
nimesulide; oral
1.3
6.1
660
5467
C01DA14
ATC
isosorbide mononitrate; oral
1.4
6.1
324
2443
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
6.1
306
2287
EB1VA, ,
NOMESCO Finland
1.3
6.1
574
4682
N03AE01
ATC
clonazepam; systemic
1.5
6.0
160
1060
J01FA09
ATC
clarithromycin; systemic
1.2
6.0
973
8403
A01AB09
ATC
miconazole; local oral
1.4
6.0
218
1538
N06AB04
ATC
citalopram; systemic
1.3
6.0
613
5043
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1460
10260
1.69
49.88
2.8
2.7
58.93
60.38
u/l
0.11
1375
9555
1821
14202
1.55
36.68
13.1
13.6
1.19
1.22
inr
1.90
1557
11781
2109
16993
1.55
36.62
5.9
6.8
11.06
11.32
umol/l
0.40
2040
16256
1529
11776
1.50
30.81
4.0
3.6
34.82
58.74
ng/l
1.62
1016
7735
1259
9535
1.48
26.46
3.5
3.2
0.15
0.14
estimate
0.02
413
2774
2422
20774
1.47
26.42
4.8
4.4
1236.41
2081.98
e6/l
0.29
29
278
1853
15144
1.44
25.94
2.8
2.7
—
—
estimate
—
0
0
2782
24903
1.45
21.26
8.4
8.4
76.62
77.97
u/l
1.17
2667
23794
1613
13173
1.39
21.01
3.8
3.6
0.02
0.08
estimate
0.99
438
2892
1150
8882
1.42
20.59
3.3
3.2
0.37
0.39
e6/l
0.15
854
6455
2053
17548
1.38
19.75
3.9
3.8
0.06
0.10
estimate
0.17
499
3340
2175
18857
1.36
18.60
5.5
5.1
6.77
6.64
mmol/l
1.63
2097
17818
2012
17250
1.36
18.39
3.9
3.8
0.00
0.00
estimate
1.08
518
3498
2032
17455
1.36
18.31
3.9
3.8
2.80
5.16
estimate
0.34
521
3572
1287
10312
1.38
18.01
3.3
3.3
68.20
90.10
e6/l
0.45
995
7818
928
7091
1.41
17.06
2.6
2.7
6.22
5.76
e6/l
0.46
843
6459
2168
18959
1.34
16.55
9.2
10.0
4.61
4.02
e9/l
16.79
1914
16514
3393
32074
1.60
15.88
17.9
15.2
26.19
22.81
mg/l
6.00
3006
26201
1158
9385
1.34
14.26
3.9
3.9
0.01
0.00
estimate
0.14
479
3280
217
1275
1.75
12.92
2.4
2.3
6660.62
5497.72
u/l
0.18
62
511
1422
11994
1.30
12.79
4.0
3.9
132.90
94.72
e6/l
0.47
1058
8340
2556
23298
1.30
12.40
3.5
3.3
46.85
45.97
u/l
0.18
2445
22124
3414
32626
1.51
11.73
19.8
17.1
139.60
139.73
mmol/l
2.63
3379
32031
978
7949
1.31
11.29
2.3
2.3
—
—
—
0
0
3417
32713
1.50
11.07
20.0
17.3
3.97
3.96
mmol/l
0.28
3379
32049
3282
31186
1.42
11.05
16.4
14.4
83.67
83.85
ml/min/173m2
0.20
3064
28840
1795
15902
1.25
9.87
8.0
7.3
1.21
1.21
mmol/l
0.47
1527
13859
2623
24283
1.27
9.64
4.7
4.4
11.61
11.27
mm/h
0.62
2466
22929
1803
16033
1.24
9.40
6.9
6.7
28.25
28.15
%
0.14
1731
15256
1165
9910
1.25
8.95
2.2
2.2
224.25
217.56
u/l
0.06
1100
9436
291
2013
1.48
8.82
3.5
3.6
5.13
5.16
kpa
0.29
280
1941
637
5062
1.31
8.38
3.0
3.0
2.62
2.64
e6/l
0.02
286
2417
316
2247
1.44
8.32
1.7
1.7
—
—
—
0
0
1656
14735
1.22
8.15
13.4
11.2
0.00
0.00
e9/l
0.17
1416
12005
1761
15775
1.22
8.07
6.8
6.6
57.19
57.05
%
0.20
1714
15122
1599
14240
1.21
7.63
7.2
6.6
1.21
1.21
mmol/l
0.64
1496
13268
1940
17613
1.21
7.55
6.9
6.8
0.20
0.19
e9/l
1.40
1760
15504
1921
17427
1.21
7.53
6.8
6.6
2.03
1.91
e9/l
0.87
1746
15463
681
5556
1.28
7.24
2.9
2.9
1.30
1.00
e6/l
0.56
332
2908
189
1249
1.54
7.16
2.3
1.9
1.40
2.01
ug/l
0.62
166
1122
242
1688
1.46
7.07
3.0
3.4
1.92
1.84
mmol/l
0.14
179
1258
2337
21685
1.21
6.93
3.3
3.1
—
—
—
0
0
333
2470
1.38
6.90
4.3
4.1
1.23
1.23
mmol/l
0.14
297
2145
2893
27427
1.24
6.88
21.0
18.5
13.53
13.55
%
0.35
2866
27059
407
3142
1.33
6.52
3.8
3.3
—
—
—
0
0
1017
8774
1.22
6.44
3.3
3.1
1321.58
1127.42
ng/l
0.48
862
7465
1106
9631
1.21
6.36
3.0
2.8
0.16
0.02
0.42
19
186
791
6664
1.24
6.28
1.4
1.3
24.02
29.15
iu/ml
1.09
257
2051
564
4571
1.28
6.28
2.5
2.6
120.20
128.03
ug/g
0.24
445
3703
1588
14319
1.19
6.18
5.2
5.2
35.81
36.08
g/l
1.14
1505
13499
941
8093
1.22
6.10
1.4
1.3
1.19
1.81
u/ml
1.95
263
2242
876
7503
1.22
5.89
1.7
1.8
1.21
1.14
mg/l
0.23
676
5787
3167
30475
1.25
5.72
6.5
6.0
39.13
38.84
mmol/mol
1.08
2990
28855
3516
34332
1.38
5.43
21.9
19.1
77.25
75.80
umol/l
1.63
3489
33972
316
2418
1.34
5.39
2.3
2.4
22.86
21.56
au/ml
0.10
36
283
968
8435
1.20
5.37
4.0
4.1
90.04
91.46
%
1.06
952
8245
135
888
1.54
5.31
1.2
1.3
—
—
—
0
0
409
3250
1.29
5.31
2.6
2.6
32.94
55.01
u/l
0.86
357
2783
2706
25696
1.19
5.30
4.9
4.4
14.64
14.66
pmol/l
0.13
2509
23916
1003
8793
1.19
5.18
2.7
2.6
335.75
335.97
umol/l
0.03
890
7907
440
3585
1.26
4.66
4.2
4.6
234.06
242.78
u/l
0.59
415
3424
290
2244
1.32
4.61
1.2
1.3
57.06
55.51
au/ml
0.05
18
159
172
1238
1.41
4.35
1.6
1.7
—
—
—
0
0
394
3198
1.26
4.32
2.6
2.3
377.97
378.33
nmol/l
0.01
372
2964
1529
14020
1.15
4.31
2.1
2.1
95.54
96.62
pmol/l
0.41
813
7512
478
3968
1.23
4.29
2.2
2.8
8.31
7.91
umol/l
0.12
424
3495
3118
30151
1.20
4.24
5.8
5.3
1.80
1.87
mu/l
2.33
2914
28258
31
139
2.24
4.24
1.1
1.1
240.64
189.16
iu/ml
0.18
31
139
212
1596
1.35
4.10
3.0
2.8
0.62
0.62
%
0.04
212
1587
340
2736
1.27
4.02
2.6
2.9
10.39
10.64
g/l
0.44
315
2541
369
2999
1.26
4.01
4.5
3.8
1.86
1.84
mmol/l
0.04
325
2601
249
1932
1.31
3.92
2.3
2.0
—
—
—
0
0
183
1358
1.37
3.89
5.3
5.4
1.61
1.63
%
0.15
175
1285
711
6190
1.18
3.86
1.3
1.3
11.15
10.49
u/ml
0.09
283
2503
1745
16231
1.14
3.86
3.4
3.1
124.25
119.26
ug/l
0.24
1645
15328
348
2830
1.25
3.78
8.8
8.0
1.46
1.33
mmol/l
0.99
348
2772
132
933
1.43
3.74
1.3
1.3
—
—
—
0
0
982
8794
1.16
3.73
1.8
1.7
20.09
20.20
nmol/l
0.08
821
7574
3157
30647
1.19
3.68
4.4
4.2
1.37
1.30
mmol/l
4.62
2944
28689
69
426
1.63
3.66
1.4
1.3
6.98
7.20
mmol/l
0.28
62
377
806
7122
1.17
3.64
1.5
1.5
2.30
2.41
g/l
0.96
493
4548
109
750
1.47
3.58
2.6
2.3
132.22
130.32
g/l
0.38
90
586
1281
11722
1.14
3.54
3.3
3.4
29.95
34.77
u/l
2.05
1215
11124
590
5093
1.19
3.53
3.0
2.6
2.36
2.33
g/l
0.47
539
4739
314
2544
1.26
3.53
3.1
2.8
66.41
66.78
g/l
0.43
287
2378
310
2523
1.25
3.36
1.2
1.2
132.00
146.49
u/ml
0.25
102
977
202
1561
1.31
3.32
1.4
1.5
—
—
—
0
0
289
2338
1.26
3.31
2.3
2.0
—
—
—
0
0
83
1228
0.67
3.31
1.6
1.5
—
—
—
0
0
861
7701
1.15
3.28
3.8
3.8
1.02
1.21
kg/l
0.50
586
5121
197
1523
1.31
3.23
3.1
3.2
1.02
1.02
ratio
0.20
182
1374
3293
32155
1.20
3.23
5.2
4.9
1.43
1.46
mmol/l
4.93
3086
30345
143
1056
1.37
3.20
3.0
3.6
25.05
24.92
mmol/l
0.23
138
979
3306
32315
1.19
3.08
5.3
5.0
4.70
4.70
mmol/l
0.07
3123
30672
345
2871
1.22
3.06
7.7
8.2
9.09
9.46
mmol/l
0.51
333
2767
623
5468
1.17
3.05
3.1
2.6
13.91
13.62
umol/l
0.45
588
5129
1617
15143
1.12
2.92
2.6
2.5
76.55
76.78
nmol/l
0.11
1475
13973
558
4884
1.17
2.83
2.0
2.1
29.56
29.59
s
0.03
547
4747
134
1001
1.35
2.82
1.3
1.4
264.32
286.90
ug/g
0.67
75
583
47
283
1.67
2.82
1.9
1.6
33.40
32.14
%
0.08
28
168
1208
11144
1.12
2.81
3.7
3.5
7.75
7.75
mmol/l
0.02
999
9569
583
5134
1.16
2.73
2.0
1.9
—
—
—
0
0
22
105
2.10
2.68
1.6
1.5
67.00
413.52
nmol/24h
0.70
22
105
534
4683
1.16
2.64
3.1
2.6
23.45
23.48
%
0.02
501
4386
177
1391
1.29
2.63
1.3
1.3
0.19
1.23
u/ml
—
8
112
312
2614
1.21
2.62
2.6
2.7
71.83
70.93
e9/l
0.15
235
1898
162
1259
1.30
2.62
5.7
5.8
0.88
0.89
%
0.14
155
1187
731
6564
1.14
2.60
1.8
1.7
71335918.74
36716528.95
pmol/l
0.52
614
5597
262
2160
1.23
2.58
2.0
1.9
1.22
1.38
g/l
0.63
245
2002
3469
34136
1.21
2.56
12.8
11.9
26.87
26.86
u/l
0.01
3384
33332
203
1630
1.26
2.54
2.3
2.2
0.09
0.01
estimate
0.68
68
538
681
6100
1.14
2.51
3.9
3.7
241.58
441.28
ng/l
1.73
487
4482
185
1474
1.27
2.48
2.0
2.0
39.87
39.38
u/l
0.11
162
1349
270
2245
1.22
2.46
3.3
3.5
4.46
4.52
pmol/l
0.41
239
2020
129
984
1.32
2.41
3.9
3.8
33.26
58.30
mg/l
1.27
108
837
129
985
1.32
2.40
3.9
3.8
36.87
58.24
mg/l
2.07
110
837
48
305
1.58
2.38
2.1
2.5
3.92
4.05
mmol/l
1.91
48
299
48
305
1.58
2.38
2.1
2.5
106.10
105.57
mmol/l
0.39
48
299
84
600
1.41
2.37
1.3
1.3
180.00
426.00
titre
—
8
50
51
330
1.55
2.35
2.1
5.1
6.70
7.37
mmol/l
0.66
40
280
1195
11113
1.11
2.33
3.1
3.6
2.35
2.35
mmol/l
0.28
1078
10215
3569
35255
1.25
2.32
26.5
22.9
254.29
254.27
e9/l
0.01
3524
34639
84
604
1.40
2.29
1.9
1.7
—
—
—
0
0
3569
35262
1.25
2.26
26.4
22.8
90.91
90.94
fl
0.13
3547
34945
3569
35264
1.25
2.24
27.1
23.3
40.65
41.02
%
0.99
3547
34931
3569
35266
1.24
2.23
26.5
22.9
4.52
4.52
e12/l
0.42
3513
34553
3569
35268
1.24
2.21
26.5
22.9
6.90
6.66
e9/l
4.58
3517
34552
3569
35273
1.24
2.17
26.7
23.0
135.95
136.20
g/l
0.50
3546
34961
117
897
1.31
2.15
1.7
1.8
—
—
—
0
0
3325
32668
1.16
2.14
5.9
5.6
2.79
2.77
mmol/l
0.37
3130
30869
376
3267
1.17
2.13
9.8
8.5
95.37
95.79
%
0.49
365
3169
41
259
1.59
2.12
2.2
2.1
11.73
15.13
%
1.51
41
254
11
43
2.56
2.07
1.0
1.0
—
—
—
0
0
34
206
1.66
2.07
1.1
1.1
0.89
1.14
u/l
—
10
93
1510
14277
1.10
2.05
2.1
1.9
1.45
1.40
mmol/l
1.30
1229
12225
88
652
1.36
2.04
1.5
1.6
—
—
—
0
0
471
4183
1.14
1.99
7.3
6.5
1.03
1.04
mmol/l
0.23
446
3908
215
1791
1.21
1.98
2.4
3.6
36.44
63.21
u/ml
1.52
205
1733
50
337
1.49
1.96
2.1
2.3
25.83
18.88
mg/l
0.39
20
132
119
928
1.29
1.95
2.1
2.1
10.87
11.62
mg/l
0.49
112
875
141
1124
1.26
1.95
2.2
2.3
319.21
456.42
ug/l
0.89
133
1060
3166
31041
1.13
1.95
5.1
4.9
5.92
5.88
mmol/l
1.14
2965
28949
163
1322
1.24
1.94
1.7
1.6
14.57
13.80
u/ml
0.06
31
327
113
878
1.30
1.91
4.0
3.5
1.56
3.41
ratio
1.90
66
484
1115
10431
1.10
1.87
4.4
4.2
11.19
7.73
mg/mmol
1.12
688
6575
45
300
1.51
1.87
2.2
2.5
1.20
1.19
mmol/l
0.24
45
294
602
5453
1.12
1.87
3.5
3.6
0.82
0.82
mmol/l
0.35
576
5172
37
236
1.57
1.87
2.4
2.6
216.16
215.05
e6/l
0.01
32
205
36
229
1.58
1.84
2.5
2.5
580.42
545.39
e6/l
0.16
31
187
40
261
1.54
1.84
2.2
2.0
—
—
—
0
0
6
17
3.53
1.83
1.0
1.1
7.16
8.10
mmol/l
—
6
17
43
286
1.51
1.81
2.4
2.7
—
—
—
0
0
242
2059
1.19
1.80
1.5
1.4
23.22
29.24
iu/l
2.35
206
1757
79
591
1.34
1.77
2.0
2.0
5.63
5.13
mmol/24h
0.58
69
530
215
1815
1.20
1.75
12.8
10.9
16.29
16.13
%
0.30
209
1751
350
3077
1.15
1.73
10.3
9.0
123.41
122.61
g/l
0.28
342
3010
68
499
1.37
1.72
3.6
3.4
0.77
0.81
nmol/l
0.43
51
416
0
47
0.00
1.70
0.0
2.1
—
—
—
0
0
56
399
1.41
1.69
2.5
2.1
7.18
5.32
umol/l
0.44
41
288
906
8439
1.10
1.66
2.4
2.3
2.73
2.76
mg/l
0.09
788
7352
35
228
1.54
1.64
1.2
1.7
—
—
—
0
0
22
127
1.74
1.64
2.2
2.1
31.55
30.38
%
0.12
22
122
96
749
1.29
1.62
4.5
5.9
1115.75
503.52
iu/ml
0.28
12
99
1093
10279
1.09
1.61
3.7
3.5
50.94
43.45
mg/l
0.54
673
6579
40
270
1.49
1.61
2.0
2.2
19.96
19.04
nmol/l
0.20
40
256
40
270
1.49
1.61
1.0
1.2
104.20
109.80
pmol/l
0.42
40
270
53
378
1.41
1.60
1.5
1.7
67.07
59.81
%
0.67
28
234
84
645
1.31
1.60
8.2
7.6
105.39
105.22
mmol/l
0.12
77
581
2725
27877
0.92
1.56
21.1
19.0
332.85
332.53
g/l
1.08
2714
27727
409
3662
1.13
1.56
9.4
8.1
11.87
12.59
kpa
2.60
390
3529
425
3817
1.13
1.55
1.9
1.8
—
—
—
0
0
59
432
1.37
1.54
1.3
1.3
227.29
323.92
pmol/l
2.46
51
369
272
2371
1.16
1.54
1.4
1.3
364.21
210.26
u/ml
0.33
258
2204
30
192
1.57
1.54
1.8
1.6
—
—
—
0
0
14
71
1.98
1.53
1.8
1.3
1.47
47.38
ug/l
—
6
28
114
917
1.25
1.52
1.1
1.1
3.02
4.67
eliau/ml
—
9
127
408
3661
1.13
1.51
9.4
8.2
5.09
5.11
kpa
0.14
389
3530
62
460
1.35
1.50
1.2
1.4
0.61
4.46
nmol/l
0.50
62
443
38
259
1.47
1.48
2.8
2.5
27.20
29.97
mg/l
0.18
25
181
80
620
1.30
1.45
1.1
1.1
22.34
16.74
au/ml
0.32
22
162
35
236
1.49
1.44
2.5
2.5
0.98
0.72
e9/l
0.38
35
226
30
197
1.53
1.40
1.8
1.6
—
—
—
0
0
42
296
1.42
1.39
1.6
1.4
1.22
1.23
promille
0.02
33
236
1005
9476
1.08
1.38
5.8
5.0
2.30
2.52
ug/l
0.27
899
8654
133
1103
1.21
1.37
1.9
1.8
1.18
1.19
g/l
0.10
127
1061
401
3624
1.12
1.34
9.5
8.1
0.82
0.95
mmol/l
0.26
336
2982
70
540
1.30
1.33
1.1
1.1
3.73
4.04
u/ml
0.05
28
240
19
113
1.68
1.31
1.3
1.5
14.47
15.58
pmol/l
0.28
19
99
32
217
1.48
1.30
1.3
1.2
0.55
0.58
ratio
0.22
17
128
9
43
2.10
1.30
15.3
11.4
4.88
5.34
mmol/l
—
9
43
155
1312
1.19
1.30
2.1
1.6
280.01
288.82
mu/l
0.18
144
1201
35
242
1.45
1.30
1.3
1.3
—
—
—
0
0
164
1396
1.18
1.29
1.7
1.6
23.33
16.35
iu/ml
—
6
39
179
1537
1.17
1.27
1.9
1.7
0.33
0.32
mg/l
0.16
91
748
129
1077
1.20
1.26
3.0
2.5
0.46
1.07
g/l
2.25
107
943
355
3199
1.12
1.26
3.9
4.3
7.04
22.17
ug/l
2.30
282
2561
124
1032
1.21
1.25
2.4
2.8
—
—
—
0
0
109
898
1.22
1.22
1.5
1.4
—
—
—
0
0
78
619
1.27
1.22
1.7
1.8
—
—
—
0
0
52
391
1.33
1.21
1.4
1.4
—
—
—
0
0
81
647
1.26
1.20
4.2
3.7
128.92
699.18
u/ml
0.80
74
601
40
289
1.39
1.19
1.2
1.2
34.26
43.16
mg/l
1.46
34
241
15
250
0.60
1.18
1.9
1.5
—
—
—
0
0
25
165
1.52
1.17
1.3
1.3
—
—
—
0
0
68
534
1.28
1.17
1.3
1.2
—
—
—
0
0
411
3756
1.11
1.14
4.8
4.7
31.48
31.86
%
0.32
300
2579
274
2449
1.13
1.13
2.3
2.3
8.17
7.80
ug/l
0.07
244
2201
397
3625
1.11
1.13
1.9
1.8
—
—
—
0
0
34
242
1.41
1.11
1.8
1.6
—
—
—
0
0
144
1231
1.18
1.11
3.2
2.4
7.22
7.34
g/l
0.39
128
1148
31
217
1.43
1.11
1.8
1.5
—
—
—
0
0
5
21
2.38
1.09
1.2
1.0
—
—
—
0
0
119
1003
1.19
1.08
1.7
2.1
2.95
9.49
iu/l
0.65
49
431
443
4078
1.10
1.07
2.3
2.1
—
—
—
0
0
598
5580
1.09
1.07
1.5
1.5
—
—
—
0
0
25
169
1.48
1.07
1.3
1.3
—
—
—
0
0
524
4864
1.09
1.06
1.8
1.7
1178.81
1151.42
nmol/l
0.28
397
3772
219
1941
1.14
1.05
7.5
7.0
24.71
24.47
mmol/l
0.44
210
1857
80
652
1.23
1.03
1.1
1.1
3.08
1.56
u/ml
0.73
35
324
125
1064
1.18
1.03
1.9
1.8
0.24
0.23
g/l
0.32
119
1021
110
926
1.19
1.03
1.2
1.1
3.80
4.29
0.30
19
130
14
83
1.69
1.01
1.3
1.2
23.34
12.71
pmol/l
—
7
36
142
1230
1.16
0.96
3.2
2.4
3.55
3.73
g/l
1.02
127
1150
50
389
1.29
0.96
1.5
1.4
—
—
—
0
0
123
1054
1.17
0.96
3.2
2.4
9.54
10.35
g/l
1.51
106
966
142
1231
1.16
0.95
3.2
2.4
4.27
4.24
g/l
0.22
127
1148
607
5699
1.08
0.94
3.3
3.1
0.80
0.73
ug/l
0.56
392
3504
7
37
1.89
0.94
1.4
1.2
3.27
5.00
nmol/l
—
7
37
23
158
1.46
0.93
1.0
1.6
—
—
—
0
0
52
409
1.28
0.93
1.3
1.3
0.18
0.18
nmol/l
0.06
42
322
36
269
1.34
0.92
1.1
1.1
—
—
—
0
0
83
690
1.21
0.91
1.2
2.1
1.01
0.88
nmol/l
1.13
77
588
6
28
2.14
0.91
1.0
1.1
—
—
—
0
0
28
201
1.40
0.91
1.6
2.9
—
—
—
0
0
18
118
1.53
0.90
2.1
1.9
2.26
1.74
ratio
0.53
18
111
119
1023
1.17
0.90
2.1
2.5
3.71
3.62
g/l
0.25
114
967
37
279
1.33
0.90
1.1
1.1
228.10
283.18
mg/l
2.32
31
243
38
288
1.32
0.89
1.1
1.3
1.32
0.95
u/ml
0.15
18
158
47
368
1.28
0.88
1.4
1.4
—
—
—
0
0
10
169
0.59
0.88
2.2
1.7
—
—
—
0
0
10
169
0.59
0.88
2.2
1.7
—
—
—
0
0
10
169
0.59
0.88
2.1
1.7
—
—
—
0
0
10
169
0.59
0.88
2.2
1.7
—
—
—
0
0
7
129
0.54
0.88
2.6
1.8
—
—
—
0
0
7
129
0.54
0.88
2.7
1.8
—
—
—
0
0
7
129
0.54
0.88
2.6
1.8
—
—
—
0
0
64
521
1.23
0.87
1.5
1.5
—
—
—
0
0
8
43
1.86
0.87
1.0
1.2
—
—
—
0
0
102
871
1.18
0.85
3.1
3.3
1.78
1.68
index
0.07
50
467
47
370
1.27
0.85
1.4
1.4
—
—
—
0
0
399
3703
1.09
0.84
2.2
2.0
—
—
—
0
0
133
1161
1.15
0.84
3.3
2.5
2.79
2.92
g/l
1.14
117
1080
78
651
1.20
0.84
1.4
1.5
—
—
—
0
0
108
929
1.17
0.83
3.0
2.4
0.00
0.03
g/l
2.26
95
845
71
588
1.21
0.83
1.1
1.1
3.70
3.33
u/ml
0.09
32
288
47
372
1.27
0.82
1.4
1.4
—
—
—
0
0
20
282
0.71
0.79
1.7
1.5
—
—
—
0
0
20
282
0.71
0.79
1.7
1.5
—
—
—
0
0
20
282
0.71
0.79
1.7
1.5
—
—
—
0
0
6
33
1.82
0.79
1.3
1.3
—
—
—
0
0
8
48
1.67
0.78
4.3
7.7
10.56
10.50
%
—
8
48
29
216
1.35
0.78
2.7
2.8
39.36
42.94
%
0.50
23
116
48
384
1.25
0.78
1.5
1.4
—
—
—
0
0
61
502
1.22
0.77
1.1
1.1
0.13
0.22
u/ml
0.38
14
167
267
2446
1.10
0.77
1.5
1.4
—
—
—
0
0
123
1080
1.14
0.74
1.8
1.8
—
—
—
0
0
17
116
1.47
0.74
1.4
1.4
—
—
—
0
0
17
116
1.47
0.74
1.4
1.4
—
—
—
0
0
82
698
1.18
0.74
1.1
1.1
4.35
4.44
u/ml
0.02
41
364
14
208
0.67
0.74
1.4
1.9
—
—
—
0
0
5
25
2.00
0.72
1.6
1.3
39.60
48.12
umol/l
—
5
25
169
1518
1.12
0.72
2.3
1.8
3.77
6.91
iu/ml
1.11
45
360
7
40
1.75
0.71
1.0
1.5
—
—
—
0
0
5
26
1.92
0.70
1.0
1.1
—
—
—
0
0
18
126
1.43
0.70
2.8
2.7
47.83
137.82
au/ml
—
6
20
70
592
1.19
0.69
3.6
2.8
2916.00
1421.24
u/ml
—
7
34
21
152
1.38
0.69
1.0
1.1
—
—
—
0
0
278
2569
1.09
0.68
2.4
2.5
0.40
0.41
e6/l
0.03
267
2437
340
3174
1.08
0.66
2.5
2.3
0.22
0.21
g/l
0.21
323
2975
5
28
1.79
0.66
1.4
2.2
4.02
2.66
mg/l
—
5
28
5
28
1.79
0.66
2.2
2.2
—
—
—
0
0
5
28
1.79
0.66
1.0
1.3
19.00
2955.57
u/l
—
5
23
31
241
1.29
0.65
1.4
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
110
970
1.14
0.65
3.5
3.2
0.40
0.34
iu/ml
0.86
65
520
21
154
1.37
0.65
1.0
1.4
151.62
163.67
mmol/24h
0.23
21
154
20
270
0.74
0.64
1.5
1.5
13.15
12.50
umol/l
0.11
20
253
40
323
1.24
0.63
1.4
1.5
—
—
—
0
0
16
112
1.43
0.63
1.0
1.3
—
—
—
0
0
20
269
0.74
0.63
1.2
1.4
195.27
196.09
pmol/l
0.01
20
269
30
381
0.79
0.63
1.1
1.2
—
—
—
0
0
12
79
1.52
0.62
1.2
1.1
—
—
—
0
0
44
360
1.22
0.62
1.9
2.0
15.27
24.58
ug/l
1.83
44
354
8
50
1.60
0.61
1.0
1.2
31.81
49.24
mg/l
—
8
44
8
50
1.60
0.61
1.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
31
245
1.27
0.59
1.4
1.2
—
—
—
0
0
58
494
1.18
0.56
5.7
6.1
383.98
362.17
umol/l
0.62
53
440
8
55
1.46
0.56
1.1
1.6
—
—
—
0
0
25
194
1.29
0.55
1.8
1.5
11.00
13.20
u/l
1.49
25
187
131
1183
1.11
0.55
2.0
2.0
—
—
—
0
0
73
635
1.15
0.55
2.9
3.4
23.09
24.92
mg/l
0.19
51
436
77
673
1.15
0.54
1.1
1.1
0.82
0.96
u/ml
0.14
21
284
198
1827
1.09
0.54
1.1
1.1
—
—
—
0
0
151
1377
1.10
0.53
1.8
1.8
1.56
1.55
g/l
0.02
127
1198
25
196
1.28
0.52
1.0
1.1
—
—
—
0
0
100
893
1.12
0.52
1.1
1.1
—
—
—
0
0
20
152
1.32
0.52
1.4
1.7
3.67
3.55
u/field
0.02
15
110
76
667
1.14
0.51
1.5
1.4
142.33
154.50
au/ml
0.34
21
192
465
4433
1.06
0.51
1.8
1.8
1.56
1.46
%
1.43
404
3937
42
352
1.20
0.50
1.1
1.1
—
—
—
0
0
7
45
1.56
0.49
1.1
1.1
48.00
61.04
ug/l
—
7
45
76
671
1.14
0.48
1.5
1.7
—
—
—
0
0
118
1070
1.11
0.48
1.5
1.4
9.84
10.19
u/l
0.11
97
871
7
46
1.52
0.48
1.0
1.0
9.37
6.20
u/ml
—
7
46
7
47
1.49
0.47
1.0
1.1
—
—
—
0
0
33
272
1.22
0.47
1.5
1.3
2.40
2.11
mmol/l
0.25
28
255
197
1832
1.08
0.47
1.7
1.7
—
—
—
0
0
117
1064
1.10
0.46
4.5
3.1
1.53
1.49
mg/l
0.24
109
991
27
219
1.23
0.45
1.1
1.1
1.09
1.05
ratio
0.82
22
179
85
761
1.12
0.44
1.4
1.5
—
—
—
0
0
99
895
1.11
0.44
3.2
2.4
0.00
0.00
g/l
-0.00
87
791
7
51
1.37
0.44
1.0
1.0
—
—
—
0
0
91
820
1.11
0.43
1.1
1.1
1.99
2.02
u/ml
0.01
43
428
25
202
1.24
0.43
1.2
1.5
1.17
1.33
nmol/l
0.46
16
152
24
193
1.25
0.43
2.4
2.0
75.13
109.36
ng/l
2.00
24
193
14
104
1.35
0.43
1.0
1.2
88.29
93.40
%
—
7
58
14
104
1.35
0.43
1.0
1.1
85.57
89.77
%
—
7
57
35
294
1.19
0.42
1.5
1.4
27725.65
111731.04
e6/l
1.28
23
197
28
338
0.83
0.42
1.9
1.4
994.16
2228.26
e6/l
2.03
19
238
5
33
1.52
0.41
1.6
1.2
6.00
5.96
mmol/l
—
5
33
8
60
1.33
0.40
1.3
1.7
—
—
—
0
0
18
141
1.28
0.40
1.2
1.2
—
—
—
0
0
5
35
1.43
0.39
1.2
1.1
102.40
89.60
titre
—
5
35
31
260
1.19
0.39
1.0
1.1
11.48
8.22
iu/ml
—
5
74
7
106
0.66
0.39
1.1
1.7
8.65
8.85
ug/l
—
7
106
18
226
0.80
0.39
1.1
1.2
—
—
—
0
0
72
801
0.90
0.38
1.5
1.5
0.90
0.94
ratio
0.50
34
483
72
801
0.90
0.38
1.5
1.5
1.02
1.21
ratio
1.74
35
487
114
1048
1.09
0.38
1.3
1.3
7.75
6.48
u/ml
—
6
94
9
66
1.36
0.38
5.1
6.6
6.21
5.39
kpa
—
9
66
72
800
0.90
0.38
1.5
1.5
1.01
1.14
ratio
0.79
34
482
46
401
1.15
0.38
1.1
1.1
—
—
—
0
0
15
192
0.78
0.38
1.0
1.1
1905.67
1448.99
miu/ml
1.24
15
192
12
89
1.35
0.37
1.1
1.4
42.20
29.86
%
—
5
63
36
308
1.17
0.37
1.3
1.4
—
—
—
0
0
78
861
0.90
0.37
1.5
1.5
51.52
61.09
ug/l
1.27
55
707
17
134
1.27
0.36
2.4
2.1
9.63
9.31
mg/l
0.08
11
115
46
403
1.14
0.36
1.2
1.2
—
—
—
0
0
76
688
1.11
0.35
2.9
2.5
134.43
118.86
ug/min
0.11
47
418
15
117
1.28
0.35
2.1
2.1
127.33
165.09
%
1.38
15
110
123
1325
0.93
0.35
1.7
1.7
5.49
4.63
mg/l
0.19
89
968
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
6
45
1.33
0.33
1.0
1.0
—
—
—
0
0
63
567
1.11
0.33
1.5
1.4
28.53
27.37
u/l
0.10
54
472
77
701
1.10
0.33
1.7
1.6
—
—
—
0
0
6
46
1.30
0.33
1.8
1.2
—
—
—
0
0
337
3509
0.96
0.32
6.4
6.3
—
—
—
0
0
109
1175
0.93
0.32
1.6
1.4
—
—
—
0
0
303
2903
1.05
0.32
2.5
2.4
13.27
13.43
nmol/l
0.13
270
2662
27
229
1.18
0.32
2.8
2.4
641.10
622.88
ml
0.11
21
159
23
192
1.20
0.32
1.0
1.2
—
—
—
0
0
72
789
0.91
0.31
1.4
1.4
—
—
—
0
0
7
97
0.72
0.30
1.4
1.6
0.43
0.50
e9/l
—
7
97
16
129
1.24
0.30
1.2
1.2
0.32
0.30
g/l
—
10
109
96
889
1.08
0.30
1.1
1.1
—
—
—
0
0
20
166
1.21
0.29
2.0
2.1
205.70
158.63
umol/l
—
10
89
7
56
1.25
0.29
1.0
1.1
—
—
—
0
0
73
669
1.09
0.29
1.6
1.5
—
—
—
0
0
17
139
1.22
0.29
2.4
4.5
—
—
—
0
0
90
834
1.08
0.28
1.7
1.7
11073.04
12297.45
e6/l
0.12
74
576
14
112
1.25
0.28
1.3
1.2
—
—
—
0
0
11
85
1.29
0.28
1.0
1.1
—
—
—
0
0
15
183
0.82
0.27
1.6
2.0
7.62
8.17
mmol/l
0.41
15
183
9
121
0.74
0.27
1.0
1.5
—
—
—
0
0
91
846
1.08
0.27
1.3
1.3
4.54
3.24
u/ml
—
5
52
58
635
0.91
0.26
1.4
1.4
0.41
0.38
nmol/l
0.13
41
489
10
77
1.30
0.26
1.4
1.1
—
—
—
0
0
47
424
1.11
0.26
1.2
1.5
3.28
3.58
ug/l
0.20
39
377
42
377
1.12
0.25
1.5
1.4
278.13
279.11
mosm/kgh2o
0.09
31
298
77
830
0.93
0.25
1.3
1.2
—
—
—
0
0
37
330
1.12
0.25
1.1
1.3
—
—
—
0
0
46
416
1.11
0.24
1.7
1.6
—
—
—
0
0
10
78
1.28
0.24
1.2
1.1
—
—
—
0
0
31
274
1.13
0.24
1.1
1.1
25.41
16.95
u/ml
0.74
15
119
91
852
1.07
0.23
1.3
1.2
42.53
49.23
u/ml
—
9
87
56
514
1.09
0.23
1.1
1.1
4.42
2.95
—
10
93
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
79
845
0.93
0.22
1.7
1.6
—
—
—
0
0
14
116
1.21
0.22
1.8
1.8
—
—
—
0
0
15
178
0.84
0.22
1.0
1.1
—
—
—
0
0
122
1158
1.06
0.21
3.0
3.7
560.74
1617.35
u/ml
0.58
109
1007
26
229
1.14
0.21
1.6
2.1
1.50
1.46
u/field
0.03
16
124
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
8.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
111
1051
1.06
0.21
1.3
1.3
19.58
8.10
u/ml
0.32
12
148
0
12
0.00
0.21
0.0
6.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
8
102
0.78
0.21
3.7
3.8
5.18
4.88
kpa
—
8
102
8
102
0.78
0.21
3.7
3.8
9.75
10.36
kpa
—
8
102
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
11
89
1.24
0.21
1.0
1.1
—
—
—
0
0
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
14
0.00
0.20
0.0
1.2
—
4932.78
—
0
9
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
219
2114
1.04
0.20
12.7
10.1
93.75
94.11
%
0.35
219
2105
84
791
1.06
0.19
1.3
1.2
3.66
3.69
mmol/l
0.14
76
751
84
791
1.06
0.19
1.4
1.4
2549.26
1332.94
e6/l
0.31
66
626
6
50
1.20
0.19
2.0
1.9
—
—
—
0
0
38
416
0.91
0.19
2.0
1.6
623.36
348.46
mu/l
0.52
30
334
62
579
1.07
0.18
1.2
1.2
2.17
3.31
u/ml
0.82
24
199
25
223
1.12
0.18
1.0
1.1
2.50
3.57
nmol/l
—
5
42
7
59
1.19
0.18
2.1
1.6
—
—
—
0
0
50
464
1.08
0.17
1.3
1.3
—
—
—
0
0
25
279
0.90
0.17
1.5
1.7
—
—
—
0
0
26
289
0.90
0.17
2.0
1.4
39914.00
86019.68
e6/l
0.72
16
167
243
2359
1.03
0.17
5.4
4.0
102.51
88.23
ng/l
1.16
219
2086
13
110
1.18
0.17
1.2
1.2
—
—
—
0
0
142
1476
0.96
0.16
1.6
1.6
915.19
1032.64
mu/l
0.77
113
1225
82
778
1.06
0.16
1.4
1.3
19.31
37.93
e6/l
0.61
62
581
766
7553
1.02
0.16
4.6
4.1
22.01
21.53
%
0.33
372
3428
6
78
0.77
0.15
1.0
1.4
—
—
—
0
0
32
293
1.09
0.15
1.0
1.1
—
—
—
0
0
106
1015
1.05
0.15
2.1
2.4
184.64
189.87
%
0.24
101
969
154
1488
1.04
0.15
1.2
1.1
1.47
1.53
g/l
2.53
154
1488
29
317
0.91
0.15
4.8
5.5
29.81
72.27
u/ml
—
8
106
9
83
1.08
0.14
1.0
1.1
—
—
—
0
0
124
1195
1.04
0.14
1.4
1.3
175.31
220.25
miu/ml
0.86
59
575
10
84
1.19
0.14
3.1
2.2
16.60
16.53
umol/l
—
10
84
18
201
0.90
0.13
1.5
1.5
—
—
—
0
0
38
354
1.07
0.13
1.1
1.2
—
—
—
0
0
38
354
1.07
0.13
1.1
1.2
—
33.89
—
0
9
40
374
1.07
0.13
1.1
1.1
—
87.48
—
0
5
53
560
0.95
0.12
1.0
1.1
14025.50
19501.01
iu/ml
0.09
13
120
314
3200
0.98
0.12
1.7
1.7
3.57
3.50
mmol/l
0.49
205
2203
32
298
1.07
0.11
2.8
3.4
13.50
12.99
index
0.10
20
183
77
739
1.04
0.11
3.0
3.0
30.38
36.49
umol/l
1.90
71
675
15
134
1.12
0.11
1.3
1.2
775.00
1059.26
titre
—
8
27
271
2662
1.02
0.10
2.7
2.6
64.55
68.85
ml/min/173m2
0.92
110
1105
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
1.4
1.7
—
—
—
0
0
34
320
1.06
0.09
1.0
1.1
—
—
—
0
0
5
47
1.06
0.09
1.2
1.5
2300006.96
718926.54
nmol/l
—
5
37
5
47
1.06
0.09
2.2
2.0
—
—
—
0
0
19
174
1.09
0.09
1.2
1.3
—
—
—
0
0
5
48
1.04
0.09
1.0
1.0
—
—
—
0
0
5
48
1.04
0.09
4.0
2.8
15.66
14.84
ml/dl
—
5
42
43
452
0.95
0.09
1.3
1.5
—
—
—
0
0
11
97
1.13
0.09
1.0
1.1
—
—
—
0
0
143
1397
1.02
0.09
1.1
1.1
0.74
0.62
ratio
1.32
19
176
19
175
1.09
0.08
1.4
1.5
28.21
29.32
umol/l
0.25
19
160
85
876
0.97
0.08
1.7
1.6
—
—
—
0
0
20
185
1.08
0.08
1.3
1.2
132.36
132.28
nmol/l
0.00
20
185
59
568
1.04
0.08
1.2
1.2
2.71
4.66
u/ml
1.66
24
254
7
64
1.09
0.08
1.7
3.0
3.29
4.76
ug/l
—
7
64
174
1707
1.02
0.08
1.3
1.4
—
—
—
0
0
32
303
1.06
0.07
1.0
1.1
—
—
—
0
0
6
71
0.84
0.07
1.0
1.1
—
—
—
0
0
33
313
1.05
0.07
1.0
1.1
—
—
—
0
0
15
137
1.10
0.07
2.4
2.3
—
—
—
0
0
32
304
1.05
0.07
1.0
1.1
—
—
—
0
0
13
118
1.10
0.07
3.4
1.8
40.45
40.97
g/l
0.14
13
118
10
89
1.12
0.06
1.0
1.1
—
—
—
0
0
9
104
0.87
0.06
1.2
1.1
—
—
—
0
0
55
532
1.03
0.06
1.5
1.5
58.68
58.76
ug/l
0.01
55
532
626
6216
1.01
0.06
2.7
2.9
2.45
2.44
mmol/l
0.62
549
5574
40
416
0.96
0.06
1.1
1.1
—
—
—
0
0
73
711
1.03
0.06
1.2
1.2
262.27
269.99
u/ml
0.10
42
435
17
182
0.93
0.05
1.4
1.2
7.00
9.58
mm/h
1.10
17
182
14
129
1.09
0.05
2.4
3.3
1.71
1.19
%
0.40
14
129
38
395
0.96
0.05
1.4
1.2
—
—
—
0
0
57
586
0.97
0.05
1.8
1.7
—
—
—
0
0
31
297
1.04
0.05
1.2
1.2
—
63.63
—
0
8
17
159
1.07
0.05
1.2
1.1
—
—
—
0
0
16
150
1.07
0.04
1.4
1.6
—
—
—
0
0
16
150
1.07
0.04
1.4
1.6
—
—
—
0
0
66
646
1.02
0.04
1.5
1.5
—
—
—
0
0
432
4294
1.01
0.04
2.0
2.0
3.65
3.50
ratio
1.28
327
3292
30
289
1.04
0.04
1.0
1.2
—
—
—
0
0
43
418
1.03
0.03
1.7
1.7
—
—
—
0
0
98
995
0.98
0.03
1.4
1.5
—
—
—
0
0
12
112
1.07
0.03
1.3
1.2
—
—
—
0
0
59
601
0.98
0.02
1.4
1.3
—
—
—
0
0
59
601
0.98
0.02
1.4
1.3
—
—
—
0
0
131
1298
1.01
0.02
1.4
1.4
—
—
—
0
0
36
368
0.98
0.01
1.4
1.7
—
—
—
0
0
223
2241
0.99
0.01
2.5
2.9
182.86
177.27
ng/l
0.06
197
2040
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
17
163
1.04
0.01
1.0
1.1
—
—
—
0
0
56
566
0.99
0.00
1.1
1.1
—
—
—
0
0
19
185
1.03
0.00
8.3
7.2
29.60
54.66
u/ml
—
5
44
50
502
1.00
0.00
1.1
1.1
4.95
3.16
eliau/ml
0.21
21
243
49
495
0.99
0.00
3.5
3.4
0.48
1.50
%
5.75
44
443
118
1182
1.00
0.00
1.6
1.5
0.10
7.02
iu/ml
0.60
24
201
34
341
1.00
0.00
1.4
1.7
—
—
—
0
0
13
126
1.03
0.00
2.8
2.7
0.62
0.62
mmol/l
0.09
13
126
12
124
0.97
0.00
1.0
1.0
—
—
—
0
0
11
106
1.04
0.00
1.0
1.2
16.54
16.64
umol/l
0.03
11
92
30
303
0.99
0.00
3.4
4.1
—
—
—
0
0
25
247
1.01
0.00
2.0
1.4
290.88
378.12
u/l
0.63
25
237
0
9
0.00
0.00
0.0
1.0
—
279.89
—
0
9
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
-0.00
1.1
1.3
—
—
—
0
0
20
200
1.00
-0.00
6.4
7.4
16.78
188.22
ug/l
0.86
14
124
0
7
0.00
-0.00
0.0
5.3
—
0.32
—
0
7
8
80
1.00
-0.00
8.0
6.3
5.38
7.61
%
—
8
80
6
67
0.90
-0.00
1.0
1.2
—
—
—
0
0
19
190
1.00
-0.00
1.2
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_APPENDOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_APPENDOTH | 1.152 [0.93, 1.43] | 0.2 |
| Birth year | 0.992 [0.98, 1.0] | 0.062 |
During the follow-up period (1.1.1998 — 31.12.2019), 155 out of 3277 females with K11_APPENDOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_APPENDOTH | 1.066 [0.88, 1.3] | 0.52 |
| Birth year | 0.991 [0.98, 1.0] | 0.089 |
During the follow-up period (1.1.1998 — 31.12.2019), 202 out of 3197 males with K11_APPENDOTH died.
Mortality risk
Mortality risk for people of age
years, who have K11_APPENDOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.088% | 0.285% |
| 5 | 0.562% | 1.552% |
| 10 | 1.442% | 3.661% |
| 15 | 2.692% | 6.828% |
| 20 | 4.667% | 11.537% |
Relationships between endpoints
↥Index endpoint: K11_APPENDOTH – Other appendicitis
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data