Generalized epilepsy

GE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G40.3
  • Hospital discharge: ICD-9 345[0-3]
  • Hospital discharge: ICD-8 34519
  • Hospital discharge: excluded ICD-8 34511
  • Cause of death: ICD-10 G40.3
  • Cause of death: ICD-9 345[0-3]
  • Cause of death: ICD-8 34519
  • Cause of death: excluded ICD-8 34511

2 out of 7 registries used, show all original rules.

1926

4. Check minimum number of events

None

1926

5. Include endpoints

None

1926

6. Filter based on genotype QC (FinnGen only)

1720

Control definitions (FinnGen only)

Control exclude
G6_EPLEPSY

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 23791 11883 11645
Only index persons 18264 9848 8416
Unadjusted period prevalence (%)
Whole population 0.33 0.34 0.33
Only index persons 0.34 0.36 0.32
Median age at first event (years)
Whole population 27.14 24.77 28.84
Only index persons 22.12 22.16 22.08

-FinnGen-

Key figures

All Female Male
Number of individuals 1720 1039 681
Unadjusted period prevalence (%) 0.35 0.37 0.31
Median age at first event (years) 27.45 24.49 31.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1795
Matched controls
17950
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
307.7
360
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
307.7
1588
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
7949.6
307.7
566
*
G40
ICD-10 Finland
Epilepsy
1989.0
307.7
319
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
34.8
307.7
611
262
N03AF02
ATC
oxcarbazepine; oral
83.1
307.7
491
81
N03AX14
ATC
levetiracetam; systemic
216.5
307.7
565
38
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
+∞
307.7
866
*
G40.3
ICD-10 Finland
Generalized idiopathic epilepsy and epileptic syndromes
+∞
307.7
353
*
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
+∞
307.7
380
*
N03AB02
ATC
phenytoin; systemic
121.8
307.7
176
16
G40.9
ICD-10 Finland
Epilepsy, unspecified
4654.5
307.7
999
5
N03AX09
ATC
lamotrigine; oral
15.8
307.7
549
488
N03AF01
ATC
carbamazepine; oral, rectal
35.1
307.7
580
241
N03AG01
ATC
valproic acid; systemic, rectal
62.5
307.7
1050
396
G40.30
ICD-10 Finland
Benign myoclonic eplilepsy in infancy
+∞
307.7
321
*
N05BA01
ATC
diazepam; systemic, rectal
8.3
307.7
612
1059
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
307.7
375
*
183
Kela drug reimbursment
Lamotrigin and topiramate
+∞
307.7
504
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
306.3
285
*
N88
ICPC
Epilepsy
+∞
252.2
236
*
N05BA09
ATC
clobazam; oral
426.4
230.1
226
6
N03AE01
ATC
clonazepam; systemic
9.3
222.3
292
368
7803A
ICD-9 Finland
General symptoms, Convulsions
24.3
215.8
156
70
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
213.9
201
*
G40.36
ICD-10 Finland
Juvenile myoclonic epilepsy [impulsive petit mal]
+∞
209.6
197
*
N03AX11
ATC
topiramate; oral
11.4
192.0
211
208
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
+∞
191.1
180
*
N05CD08
ATC
midazolam; nasal, systemic
18.3
183.2
150
89
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
12.7
180.8
183
159
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
+∞
163.0
154
*
G40.89
ICD-10 Finland
Other epilepsy
+∞
159.8
151
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
+∞
144.8
137
*
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
19.8
143.1
112
60
G40.10
ICD-10 Finland
Simple partial seizures
+∞
140.5
133
*
3459X
ICD-9 Finland
Epilepsy, unspecified
+∞
137.3
130
*
N03AX18
ATC
lacosamide; systemic
715.8
136.6
133
*
34519
ICD-8 Finland
Epilepsy, Generalisata convulsiva NUD
+∞
125.5
119
*
34599
ICD-8 Finland
Epilepsy, Other and unspecified
+∞
125.5
119
*
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
+∞
115.9
110
*
AA1AD
NOMESCO Finland
CT of head and brain
3.1
97.9
578
2416
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
990.0
96.9
94
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.8
96.5
190
362
G40.35
ICD-10 Finland
Juvenile absence epilepsy
+∞
95.7
91
*
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
+∞
94.6
90
*
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
+∞
93.6
89
*
34510
ICD-8 Finland
Epilepsy, """"Grand mal""""
+∞
92.5
88
*
3450A
ICD-9 Finland
Epilepsy, Generalised nonconvulsive epilepsy
+∞
90.4
86
*
3453A
ICD-9 Finland
Epilepsy, Grand mal status
+∞
90.4
86
*
N03AD01
ATC
ethosuximide; oral
+∞
85.1
81
*
G40.33
ICD-10 Finland
Juvenile absence epilepsy
+∞
85.1
81
*
N03AX22
ATC
perampanel; oral
+∞
85.1
81
*
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
+∞
84.0
80
*
XA400
NOMESCO Finland
EEG
29.8
82.7
55
19
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
81.9
78
*
N03AX23
ATC
brivaracetam; systemic
+∞
80.8
77
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
127.4
79.6
85
7
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.4
74.3
99
124
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.7
72.3
252
751
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.6
62.8
228
696
N03AX15
ATC
zonisamide; oral
89.7
62.4
69
8
N03AG04
ATC
vigabatrin; oral
+∞
61.8
59
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.3
60.7
262
891
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
10.0
54.7
63
65
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
5.4
52.2
106
206
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
9.2
51.3
63
71
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.6
48.9
169
497
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.3
47.9
199
658
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.7
46.2
283
1161
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
45.0
43
*
3454B
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[TEMPORAALIEPILEPTINEN POISSAOLOKOHTAUS]
+∞
42.9
41
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.5
41.6
303
1348
N05AX08
ATC
risperidone; systemic
3.0
41.4
204
743
R56.0
ICD-10 Finland
Febrile convulsions
10.7
40.3
44
42
N05AA02
ATC
levomepromazine; systemic
4.2
40.2
110
273
R55
ICD-10 Finland
Syncope and collapse
2.8
40.1
220
849
Z2445
NOMESCO Finland
Psychologist
3.4
39.7
150
466
G40.0
ICD-10 Finland
Localization-related (focal)(partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset
+∞
38.7
37
*
34532
ICD-8 Finland
Epilepsy, Partialis (focalis) generalisata
+∞
38.7
37
*
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
+∞
37.6
36
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
36.9
309
1458
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
36.6
35
*
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
+∞
36.6
35
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.0
36.4
175
627
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
35.7
451
2505
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
34.8
165
587
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
34.6
543
3254
N05AD01
ATC
haloperidol; systemic
4.8
34.1
78
168
G41.0
ICD-10 Finland
Grand mal status epilepticus
77.7
33.9
38
5
N03AF04
ATC
eslicarbazepine; oral
+∞
31.3
30
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
30.9
276
1332
N05AH03
ATC
olanzapine; systemic
2.7
30.0
171
670
34530
ICD-8 Finland
Epilepsy, Psychomotorica
+∞
29.2
28
*
34500
ICD-8 Finland
Epilepsy, """"Petit mal""""
+∞
28.2
27
*
N06AB04
ATC
citalopram; systemic
2.0
27.0
369
2084
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
26.6
382
2193
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
26.4
265
1337
N07
ICPC
Convulsion/seizure
37.3
26.2
33
9
R42
ICD-10 Finland
Dizziness and giddiness
1.9
26.2
378
2174
G40.7
ICD-10 Finland
Petit mal, unspecified, without grand mal seizures
+∞
26.1
25
*
W19
ICD-10 Finland
Unspecified fall
2.3
25.7
206
947
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
5.6
25.6
49
90
A06AD11
ATC
lactulose; oral
2.3
25.4
219
1038
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.6
25.1
159
656
F44.5
ICD-10 Finland
Dissociative convulsions
+∞
25.1
24
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
24.9
415
2497
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.9
24.6
118
421
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.4
24.2
177
780
N05AH04
ATC
quetiapine; oral
1.9
24.1
376
2211
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.9
23.8
112
396
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
23.8
312
1732
N05CD07
ATC
temazepam; oral
2.4
23.6
170
744
N05AH02
ATC
clozapine; systemic
4.2
23.3
63
155
R40.2
ICD-10 Finland
Coma, unspecified
9.8
23.3
27
28
G40.34
ICD-10 Finland
Epilepsy with grand mal seizures on awakening
+∞
23.0
22
*
G40.80
ICD-10 Finland
Epilepsy with continuous EEG spike-waves during slow wave sleep
+∞
23.0
22
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
9.1
22.1
27
30
Z2446
NOMESCO Finland
Social worker
2.4
22.0
164
728
34598
ICD-8 Finland
Epilepsy, Alia definita
+∞
21.9
21
*
G40.8
ICD-10 Finland
Other epilepsy
+∞
21.9
21
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.9
21.7
64
168
S06.0
ICD-10 Finland
Concussion
2.1
21.5
232
1197
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
6.6
21.3
34
52
3454X
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[ALII DISTURBATIONES CONSCIENTAE EPILEPTICI]
+∞
20.9
20
*
G40.31
ICD-10 Finland
Benign neonatal convulsions (familial)
+∞
20.9
20
*
G40.59
ICD-10 Finland
Other special epileptic syndromes
+∞
20.9
20
*
N03AG06
ATC
tiagabine; oral
+∞
20.9
20
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
7.4
20.8
30
41
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.1
20.6
90
305
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
42.2
20.5
25
6
R11
ICD-10 Finland
Nausea and vomiting
2.2
20.4
192
940
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
20.3
701
5102
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.7
20.1
46
99
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
3.9
19.9
58
151
3069, ,
Kela drug reimbursment
+∞
19.8
19
*
N05CD02
ATC
nitrazepam; oral
5.3
19.4
39
75
N03AA02
ATC
phenobarbital; systemic
55.6
18.9
22
*
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
3.8
18.9
57
152
WX892
NOMESCO Finland
Monitored bed care
2.4
18.8
137
602
1541, ,
Kela drug reimbursment
+∞
18.8
18
*
N04AA02
ATC
biperiden; systemic
4.2
18.7
49
118
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
18.6
359
2235
G41.2
ICD-10 Finland
Complex partial status epilepticus
191.9
18.6
19
*
N05AF03
ATC
chlorprothixene; systemic
3.6
18.5
62
178
A28
ICPC
Limited function/disability NOS
2.0
18.5
225
1211
R53
ICD-10 Finland
Malaise and fatigue
1.7
18.0
470
3173
N05AB03
ATC
perphenazine; systemic, rectal
3.1
17.8
77
259
G40.37
ICD-10 Finland
Baltic myoclonus
+∞
17.7
17
*
N03AX25
ATC
cenobamate; oral
+∞
17.7
17
*
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
37.1
17.6
22
6
C03CA01
ATC
furosemide; systemic
1.7
17.5
337
2095
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.6
17.4
101
399
TAB00
NOMESCO Finland
Lumbar puncture
2.6
17.3
99
388
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.4
17.3
128
567
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
50.5
17.0
20
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
17.0
159
776
N05BA04
ATC
oxazepam; oral
1.6
16.7
432
2899
3452A
ICD-9 Finland
Epilepsy, Petit mal status
+∞
16.7
16
*
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
18.1
16.5
25
14
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
5.8
15.9
29
51
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.1
15.8
67
223
Z3231
NOMESCO Finland
Registered nurse
1.6
15.8
457
3148
S01.0
ICD-10 Finland
Open wound of scalp
2.3
15.7
129
597
H53.4
ICD-10 Finland
Visual field defects
4.2
15.6
41
99
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.4
15.5
57
174
7802X
ICD-9 Finland
General symptoms, Syncope and collapse[SYNCOPE ET COLLAPSUS NUD]
13.9
15.5
26
19
N05AF05
ATC
zuclopenthixol; systemic
5.7
15.1
28
50
Y0209
ICD-8 Finland
Examination of the nervous system and sensory organs, Nervous system
11.9
15.1
27
23
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
15.0
161
827
G41.1
ICD-10 Finland
Petit mal status epilepticus
+∞
14.6
14
*
A04
ICPC
Weakness/tiredness general
1.7
14.5
299
1887
N05AC02
ATC
thioridazine; oral
3.6
14.4
47
133
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
3.5
14.3
48
138
R51.80
ICD-10 Finland
Headache
1.7
14.3
323
2086
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.1
14.2
132
642
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
14.1
192
1071
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
6.7
14.0
22
33
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
12.8
13.9
24
19
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
4.8
13.8
31
66
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
13.7
118
556
P99
ICPC
Psychological disorders other
2.6
13.6
79
312
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
13.6
653
4996
L28
ICPC
Limited function/disability (L)
1.8
13.6
244
1480
T90.5
ICD-10 Finland
Sequelae of intracranial injury
4.8
13.6
30
63
34539
ICD-8 Finland
Epilepsy, Partialis (focalis) NUD
+∞
13.6
13
*
4300A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]
25.9
13.4
18
7
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
11.6
13.3
24
21
N05AX12
ATC
aripiprazole; systemic
2.3
13.3
107
491
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.4
13.2
47
141
SPAT1301
SPAT
No procedures
1.5
13.2
481
3472
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.2
13.1
50
157
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
12.6
161
879
SPAT1229
SPAT
Assessment of need for aid
2.3
12.5
92
406
AAA35
NOMESCO Finland
Insertion of subdural electrodes
+∞
12.5
12
*
N29
ICPC
Neurological sympt/complt other
3.7
12.5
39
107
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
5.7
12.4
23
41
P72
ICPC
Schizophrenia
3.2
12.4
49
157
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
12.3
196
1147
N28
ICPC
Limited function/disability (N)
4.2
12.3
32
77
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
6.1
12.1
21
35
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
12.0
304
2014
P76
ICPC
Depressive disorder
1.9
12.0
157
863
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
3.6
11.7
38
107
F83
ICD-10 Finland
Mixed specific developmental disorders
4.1
11.7
32
80
R32
ICD-10 Finland
Unspecified urinary incontinence
3.2
11.5
44
138
P85
ICPC
Mental retardation
11.2
11.5
21
19
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.5
11.5
69
278
3458X
ICD-9 Finland
Epilepsy, Other forms of epilepsy
+∞
11.5
11
*
G40.50
ICD-10 Finland
Epilepsia partialis continua [Kozhevnikof]
+∞
11.5
11
*
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
4.4
11.5
28
64
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
11.3
160
901
RS222, ,
NOMESCO Finland
4.2
11.3
30
73
SPAT1254
SPAT
Administration of medicine
1.7
11.3
237
1495
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.9
11.3
51
177
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
35.3
11.3
14
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
11.2
365
2558
P29
ICPC
Psychological sympt/compl other
1.8
11.2
186
1100
G81.9
ICD-10 Finland
Hemiplegia, unspecified
5.0
11.2
24
49
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
11.2
399
2852
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
11.2
189
1124
R60.9
ICD-10 Finland
Oedema, unspecified
2.3
11.2
82
362
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
3.8
11.0
33
88
G25.0
ICD-10 Finland
Essential tremor
3.2
11.0
44
142
N05CF01
ATC
zopiclone; oral
1.5
11.0
434
3166
A46
ICD-10 Finland
Erysipelas
1.7
11.0
192
1154
R41.0
ICD-10 Finland
Disorientation, unspecified
3.2
10.9
42
133
F40.9
ICD-10 Finland
Phobic anxiety disorder, unspecified
5.2
10.8
22
43
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
5.2
10.8
22
43
WX730
NOMESCO Finland
Conventional respirator
4.3
10.8
27
63
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.2
10.7
41
129
XCK00
NOMESCO Finland
Perimetry
2.3
10.7
78
344
SPAT1240
SPAT
Therapeutic discussion
1.7
10.6
217
1359
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.9
10.6
127
678
A10AB01
ATC
insulin (human); parenteral
2.4
10.6
69
289
N01
ICPC
Headache
1.6
10.6
273
1814
ZY010
NOMESCO Finland
Hospital outpatient
2.0
10.5
123
651
79399
ICD-8 Finland
Observation, without need for further medical care, Unspecified
5.0
10.5
22
44
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.4
10.5
68
284
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
4.7
10.5
24
52
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
4.7
10.5
24
52
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.1
10.4
98
479
J01EA01
ATC
trimethoprim; systemic
1.5
10.4
375
2681
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
110.7
10.4
11
*
96698
ICD-8 Finland
Other antiepileptics
+∞
10.4
10
*
34520
ICD-8 Finland
Epilepsy, Status epilepticus
+∞
10.4
10
*
R25.2
ICD-10 Finland
Cramp and spasm
2.9
10.3
46
159
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
23.5
10.2
14
6
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
5.3
10.1
20
38
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.9
10.1
47
166
A29
ICPC
General symptom/complaint other
1.7
10.1
201
1252
ZXD05
NOMESCO Finland
Urgent procedure
1.4
10.1
480
3625
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
10.0
388
2815
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
10.0
629
4990
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.6
10.0
238
1551
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
9.9
486
3685
K07
ICPC
Swollen ankles/oedema
2.5
9.9
63
261
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
9.9
174
1046
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
9.8
123
2142
N06AX16
ATC
venlafaxine; oral
1.6
9.8
251
1663
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
20.1
9.8
14
7
R1250
NOMESCO Finland
Evaluation of functional capability
2.8
9.8
47
169
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
9.7
146
838
N18
ICPC
Paralysis/weakness
3.7
9.7
30
82
C07AA05
ATC
propranolol; systemic
1.5
9.7
342
2433
6489X
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other current conditions classifiable elsewhere
13.4
9.7
16
12
N03AX12
ATC
[U] gabapentin; oral
1.6
9.7
221
1425
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.6
9.6
248
1645
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.0
9.6
99
501
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.3
9.6
71
315
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
4.6
9.5
22
48
F61.0
ICD-10 Finland
Mixed personality disorders
3.1
9.5
39
128
SPAT1216
SPAT
Assessment of functional ability
1.7
9.5
180
1105
SPAT1210
SPAT
Application of cast or individual aid
2.3
9.5
69
304
78259
ICD-8 Finland
Symptoms referable to cardiovascular and lymphatic system, Syncope (lipothymia) alia sive NUD
30.2
9.4
12
*
AAJ99
NOMESCO Finland
Other operation for epilepsy
+∞
9.4
9
*
G40.51
ICD-10 Finland
Epileptic seizures related to alcohol
+∞
9.4
9
*
G41.8
ICD-10 Finland
Other status epilepticus
+∞
9.4
9
*
K90
ICPC
Stroke/cerebrovascular accident
3.2
9.4
37
119
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
9.3
123
678
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
9.3
105
549
F20.0
ICD-10 Finland
Paranoid schizophrenia
4.9
9.3
20
41
OAB43, ,
SPAT
0.7
9.3
448
5769
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.2
9.3
80
379
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
9.3
233
1537
A10AA02, ,
ATC
2.5
9.2
55
222
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.1
9.1
38
126
H03AA01
ATC
levothyroxine sodium; systemic
1.5
9.1
329
2348
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.6
9.1
29
81
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
4.8
9.1
20
42
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
4.6
9.1
21
46
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
9.0
77
363
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.8
9.0
127
715
SPAT1263
SPAT
Sampling
1.4
9.0
660
5348
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
8.9
153
913
M41.4
ICD-10 Finland
Neuromuscular scoliosis
18.7
8.9
13
7
R5599
NOMESCO Finland
Other rehabilitation service
2.6
8.9
52
207
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
24.1
8.9
12
5
2161
FHL
Neck ligation, big brain
24.1
8.9
12
5
S01.9
ICD-10 Finland
Open wound of head, part unspecified
3.1
8.7
35
114
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
50.2
8.7
10
*
R50.9
ICD-10 Finland
Fever, unspecified
1.5
8.6
267
1844
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
2.6
8.6
47
181
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
2.0
8.6
86
431
N03AX16
ATC
[U] pregabalin
1.5
8.6
302
2142
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
8.6
122
689
S42.0
ICD-10 Finland
Fracture of clavicle
2.5
8.6
51
205
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
8.6
272
1889
N05BA06
ATC
lorazepam; systemic, sublingual
2.2
8.6
74
351
S82.6
ICD-10 Finland
Fracture of lateral malleolus
1.9
8.6
99
523
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
16.4
8.6
13
8
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.1
8.5
81
399
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
3.0
8.5
36
121
J01DA01
ATC
[U] cefalexin
1.3
8.5
952
8204
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
7.4
8.4
19
26
R4150
NOMESCO Finland
Neuropsychological rehabilitation
4.3
8.4
21
49
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.6
8.4
47
184
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
7.9
8.4
18
23
N99
ICPC
Neurological disease other
4.0
8.3
23
58
S03.20
ICD-10 Finland
Dental dislocation
4.0
8.3
23
58
3456B
ICD-9 Finland
Epilepsy, Infantile spasms[EPILEPSIA MYOCLONICA CUM ASTASIA]
+∞
8.3
8
*
V628A
ICD-9 Finland
Other psychosocial circumstances, Other psychological or physical stress, not elsewhere classified
+∞
8.3
8
*
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
8.3
447
3434
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
8.2
153
935
OAA67, ,
SPAT
0.6
8.2
174
2649
N03AA03
ATC
primidone; oral
14.5
8.2
13
9
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
14.5
8.2
13
9
S70.0
ICD-10 Finland
Contusion of hip
2.3
8.2
59
260
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
8.2
157
968
RS221, ,
NOMESCO Finland
3.0
8.1
35
119
Z2221
NOMESCO Finland
Medical doctor
1.4
8.1
422
3221
J46
ICD-10 Finland
Status asthmaticus
2.5
8.0
49
200
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.5
8.0
49
200
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
22.1
8.0
11
5
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
6.3
8.0
20
32
J01FF01
ATC
clindamycin; systemic
1.4
8.0
387
2916
Z3226
NOMESCO Finland
Physiotherapist
1.5
7.9
266
1868
N06AB10
ATC
escitalopram; oral
1.4
7.9
373
2795
R41.3
ICD-10 Finland
Other amnesia
2.9
7.9
35
121
F99
ICD-10 Finland
Mental disorder, not otherwise specified
2.5
7.9
48
196
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
6.1
7.8
20
33
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
6.1
7.8
20
33
SPAT1050
SPAT
Extensive neurological examination
3.0
7.8
34
116
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.6
7.8
43
167
K92.0
ICD-10 Finland
Haematemesis
2.8
7.7
38
139
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
3.1
7.7
31
101
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
45.2
7.7
9
*
31099
ICD-8 Finland
Borderline mental retardation, Other and unspecified
45.2
7.7
9
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
7.7
125
735
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
15.1
7.7
12
8
N05AL01
ATC
sulpiride; systemic
3.6
7.7
25
71
F39
ICD-10 Finland
Unspecified mood [affective] disorder
2.5
7.7
45
180
N06AX11
ATC
mirtazapine; oral
1.4
7.7
511
4055
N05AB04
ATC
prochlorperazine; systemic, rectal
3.3
7.7
28
86
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
7.6
143
876
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
7.6
155
971
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
7.6
308
2245
L17
ICPC
Foot/toe symptom/complaint
1.4
7.6
462
3614
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.3
7.5
54
238
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
2.6
7.4
43
171
G43.9
ICD-10 Finland
Migraine, unspecified
1.7
7.4
133
804
S20.2
ICD-10 Finland
Contusion of thorax
1.9
7.4
85
448
R4120
NOMESCO Finland
Occupational therapy
1.9
7.4
99
549
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
4.0
7.3
20
50
WX704
NOMESCO Finland
Intubation
1.7
7.3
124
738
Z50.5
ICD-10 Finland
Speech therapy
2.8
7.3
35
126
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
7.3
290
2103
30188
ICD-8 Finland
Personality disorders, Alia definita
8.4
7.3
15
18
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
7.3
360
2716
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
10.9
7.3
13
12
N03AF03
ATC
rufinamide; oral
+∞
7.3
7
*
AAJ20
NOMESCO Finland
Excision of epileptic focus
+∞
7.3
7
*
N03AX17
ATC
stiripentol; oral
+∞
7.3
7
*
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.0
7.3
75
381
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.4
7.3
46
191
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.1
7.3
65
313
U04
ICPC
Incontinence urine
2.1
7.3
69
340
N05BA02
ATC
chlordiazepoxide; systemic
2.7
7.3
37
138
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.9
7.3
21
55
N05AD03
ATC
melperone; systemic
3.9
7.3
21
55
85000
ICD-8 Finland
Concussion, Current or unspecified
2.8
7.2
35
127
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
7.2
79
411
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
7.2
459
3614
2152
FHL
Extraction, big brain
20.1
7.1
10
5
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.2
7.1
57
263
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.7
7.1
133
815
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.6
7.1
38
146
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
8.8
7.0
14
16
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.4
7.0
45
188
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
4.2
7.0
18
43
IEY01
NOMESCO Finland
Psychoeducation, individual
3.2
7.0
27
86
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.2
7.0
27
86
IEY08
NOMESCO Finland
Psychiatric coaching, domestic and community skills
7.0
7.0
16
23
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
7.0
93
516
SPAT1172
SPAT
Guidance concerning hydration
3.3
7.0
25
76
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
7.0
162
1048
J01DB01
ATC
cefalexin; oral
1.4
7.0
1384
12771
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
1.8
6.9
100
569
R60.0
ICD-10 Finland
Localized oedema
1.6
6.9
155
994
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
5.5
6.9
19
35
A10AA01, ,
ATC
2.4
6.9
46
196
N91.1
ICD-10 Finland
Secondary amenorrhoea
2.5
6.9
43
178
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.1
6.8
66
328
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
6.8
130
800
N30.0
ICD-10 Finland
Acute cystitis
1.5
6.8
257
1845
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
4.1
6.8
18
44
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
6.7
6.8
16
24
M79.6
ICD-10 Finland
Pain in limb
1.3
6.8
668
5592
43090
ICD-8 Finland
Subarachnoid haemorrhage, Postaneurysma sacculare, hypertonia non indicata
40.2
6.8
8
*
C02AC05
ATC
moxonidine; oral
2.3
6.7
51
230
N06AA09
ATC
amitriptyline; systemic
1.7
6.7
108
634
X58
ICD-10 Finland
Exposure to other specified factors
1.5
6.7
254
1824
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
3.9
6.7
19
49
F22.0
ICD-10 Finland
Delusional disorder
3.2
6.7
25
78
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
22.6
6.7
9
*
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
22.6
6.7
9
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.2
6.6
54
251
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
2.4
6.6
42
175
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
2.0
6.6
65
325
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
1.9
6.6
77
409
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
5.9
6.6
17
29
G04BD09
ATC
trospium; oral
2.9
6.6
29
100
G04BD07
ATC
tolterodine; oral
2.2
6.6
54
252
QAB00
NOMESCO Finland
Suture of skin of head or neck
3.2
6.6
25
79
S21
ICPC
Skin texture symptom/complaint
1.5
6.6
218
1526
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.5
6.6
177
1186
30040
ICD-8 Finland
Neuroses, Neurotico-depressiva
8.7
6.6
13
15
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
2.2
6.5
53
246
SPAT1104
SPAT
Monitoring of emergency patient
1.9
6.5
84
461
79199
ICD-8 Finland
Headache
3.8
6.5
19
50
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
10.1
6.5
12
12
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
1.9
6.5
78
418
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
6.5
200
1380
3141A
ICD-9 Finland
Hyperkinetic syndrome of childhood, Hyperkinesis with developmental delay
70.1
6.4
7
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.3
6.4
23
70
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
7.4
6.4
14
19
SPAT1251
SPAT
Organisation of medication
2.3
6.4
47
210
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
4.1
6.4
17
42
H50.1
ICD-10 Finland
Divergent concomitant strabismus
4.1
6.4
17
42
G44.2
ICD-10 Finland
Tension-type headache
1.5
6.4
224
1587
J01CA04
ATC
amoxicillin; systemic
1.4
6.3
1447
13504
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
6.3
89
503
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.3
188
1287
30180
ICD-8 Finland
Personality disorders, Immatura
9.3
6.3
12
13
R4120, ,
SPAT
3.4
6.3
22
66
SPAT1234
SPAT
Support of social functional capacity
2.0
6.3
64
325
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.8
6.3
95
549
F44.4
ICD-10 Finland
Dissociative motor disorders
18.1
6.3
9
5
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
18.1
6.3
9
5
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.2
6.3
48
218
AAJ15
NOMESCO Finland
Hippocampectomy
+∞
6.3
6
*
F73.0
ICD-10 Finland
Profound mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
6.3
6
*
3457B
ICD-9 Finland
Epilepsy, Epilepsia partialis continua[EPILEPSIA PARTIALIS CONTINUA]
+∞
6.3
6
*
N03AX24
ATC
cannabidiol; oral
+∞
6.3
6
*
3046, ,
Kela drug reimbursment
+∞
6.3
6
*
199
Kela drug reimbursment
Rufinamide
+∞
6.3
6
*
34300
ICD-8 Finland
Cerebral spastic infantile paralysis, Hemiplegia spastica
+∞
6.3
6
*
31599
ICD-8 Finland
Unspecified mental retardation, Other and unspecified
+∞
6.3
6
*
34533
ICD-8 Finland
Epilepsy, Partialis (focalis) alia
+∞
6.3
6
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.2
684
5792
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
3.0
6.2
26
87
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
26.8
6.2
8
*
2910A
ICD-9 Finland
Alcoholic psychoses, Alcohol withdrawal delirium
26.8
6.2
8
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
7.0
6.2
14
20
R13
ICD-10 Finland
Dysphagia
1.8
6.2
94
543
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
6.2
201
1400
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.6
6.2
158
1045
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.7
6.2
99
581
L16
ICPC
Ankle symptom/complaint
1.5
6.2
202
1409
L03
ICPC
Low back symptom/complaint
1.3
6.2
459
3684
F05
ICPC
Visual disturbance other
2.1
6.2
56
272
N05AA01
ATC
chlorpromazine; systemic, rectal
3.2
6.2
23
72
W10
ICD-10 Finland
Fall on and from stairs and steps
1.9
6.1
78
427
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.5
6.1
36
145
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
6.1
135
863
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.7
6.1
116
714
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.1
359
2782
Z71.8
ICD-10 Finland
Other specified counselling
1.3
6.1
578
4798
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
1.9
6.1
78
428
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
6.1
189
1305
A01
ICPC
Pain general/multiple sites
1.6
6.1
144
937
A03FA02
ATC
cisapride; oral, rectal
1.8
6.1
82
458
29599
ICD-8 Finland
Schizophrenia, Unspecified type
8.6
6.1
12
14
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
3.6
6.0
19
53
F50.9
ICD-10 Finland
Eating disorder, unspecified
2.7
6.0
30
111
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.0
887
7783
D01
ICPC
Abdominal pain/cramps general
1.5
6.0
225
1612
L84
ICPC
Back syndrome without radiat pain
1.9
6.0
78
430
AA3AD
NOMESCO Finland
CT of face
5.2
6.0
17
33
WYA20
NOMESCO Finland
Home visit
2.9
6.0
26
89

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
449
172
34.48
307.65
5.4
6.4
399.63
371.25
umol/l
1.45
416
148
753
3873
2.63
83.13
3.5
2.1
182.75
199.70
u/l
0.33
736
3707
1007
6752
2.12
51.87
8.0
7.7
1.21
1.21
mmol/l
1.90
896
5921
914
5992
2.07
49.02
7.2
7.5
1.21
1.21
mmol/l
2.65
873
5594
146
414
3.75
44.46
2.5
2.4
627.03
330.25
ug/l
0.43
140
390
1125
8382
1.92
37.31
6.4
5.3
6.42
6.47
mmol/l
0.30
1064
7812
104
303
3.58
30.31
2.7
3.7
34.13
33.36
umol/l
0.15
94
282
287
1524
2.05
24.84
4.7
6.1
7.37
7.38
ph
0.25
174
919
578
3864
1.73
24.14
4.3
4.2
7.40
7.40
ph
0.51
435
2712
255
1349
2.04
22.16
7.7
9.5
7.42
7.41
ph
0.15
154
733
272
1475
1.99
22.04
4.6
6.1
1.22
1.58
mmol/l
0.82
231
1249
276
1517
1.97
21.49
4.6
6.0
5.80
5.81
kpa
0.08
259
1477
252
1351
2.01
21.04
7.6
9.5
5.10
5.11
kpa
0.10
245
1296
249
1330
2.01
21.01
7.7
9.6
0.99
0.77
mmol/l
0.35
203
1091
252
1352
2.00
21.00
7.6
9.4
12.96
12.67
kpa
0.33
244
1300
215
1109
2.07
19.92
8.3
10.3
123.26
122.72
g/l
0.15
209
1087
949
7444
1.58
19.81
7.4
7.2
0.66
0.68
%
0.53
905
7034
724
5338
1.60
19.66
4.0
3.5
28.49
31.21
u/l
1.69
690
5087
365
2251
1.78
19.65
3.8
4.6
0.81
0.82
mmol/l
0.73
347
2147
949
7468
1.57
19.35
7.4
7.2
8.92
8.54
%
3.99
906
7070
947
7451
1.57
19.31
7.3
7.1
2.56
2.88
%
4.33
904
7047
509
3454
1.66
19.29
5.2
4.1
—
—
—
0
0
754
5642
1.58
19.05
12.8
11.2
1.17
1.18
inr
0.14
637
4684
785
5944
1.57
18.74
5.3
5.5
36.00
36.73
g/l
3.16
746
5610
1007
8068
1.57
18.71
7.1
7.0
0.04
0.04
e9/l
1.46
878
6996
617
4419
1.60
18.69
2.8
2.6
60.59
59.47
u/l
0.05
576
4144
1005
8059
1.56
18.51
7.1
7.0
0.58
0.56
e9/l
1.25
877
6988
955
7596
1.55
18.06
7.0
6.9
53.89
55.78
%
5.23
923
7311
1029
8329
1.55
17.92
7.8
7.3
0.17
0.19
e9/l
2.01
911
7346
968
7732
1.55
17.88
7.4
7.1
31.22
29.63
%
4.27
931
7391
1023
8280
1.55
17.73
7.3
7.0
2.00
2.01
e9/l
0.15
908
7374
645
4777
1.55
16.38
4.1
3.2
24.74
72.26
ng/l
1.36
395
2794
216
1200
1.91
16.08
8.2
10.1
95.82
95.75
%
0.06
209
1164
141
681
2.16
15.44
8.5
6.9
24.61
24.36
mmol/l
0.29
135
648
908
7292
1.50
15.41
6.3
6.5
8.96
11.89
umol/l
9.36
856
6945
509
3617
1.57
15.34
1.8
1.6
19.92
19.98
nmol/l
0.03
460
3169
297
1885
1.69
14.03
1.7
1.7
1106.15
1139.47
nmol/l
0.25
237
1470
1060
8884
1.47
13.86
11.6
9.8
3.86
3.98
e9/l
0.85
923
7743
545
4005
1.52
13.84
3.5
2.7
—
—
—
0
0
225
1330
1.79
13.67
4.3
5.6
4.80
4.79
kpa
0.04
211
1295
152
804
1.97
13.03
4.6
5.3
128.85
130.68
g/l
0.43
144
783
193
1105
1.84
13.00
4.4
5.9
5.16
5.09
kpa
0.69
186
1071
134
681
2.05
12.84
9.8
12.4
16.43
16.11
%
0.66
129
654
33
80
4.18
12.52
1.8
3.8
163.81
138.07
umol/l
0.15
16
46
218
1310
1.76
12.48
7.3
10.8
—
—
—
0
0
1250
10924
1.48
12.44
8.2
7.7
78.96
79.75
u/l
0.28
1181
10415
729
5780
1.44
12.23
2.1
2.0
96.48
97.10
pmol/l
0.14
396
3197
360
2473
1.57
12.22
4.2
3.5
200.85
519.10
ng/l
2.39
239
1630
58
207
2.86
12.18
1.5
1.7
67.63
68.72
mmol/l
0.05
46
174
187
1085
1.81
12.05
4.5
5.9
7.41
7.41
ph
1.34
145
901
111
540
2.13
11.95
4.8
4.0
24.96
25.18
mmol/l
0.26
105
520
101
474
2.20
11.90
8.2
5.6
0.91
0.88
%
0.35
94
445
311
2079
1.60
11.83
2.0
2.7
28.86
29.52
s
0.90
301
2025
1601
14837
1.73
11.70
21.9
14.6
138.78
139.63
mmol/l
23.30
1567
14542
605
4666
1.45
11.63
3.0
3.3
2.34
2.35
mmol/l
2.00
559
4332
80
350
2.35
11.14
1.5
2.0
—
—
—
0
0
83
373
2.28
10.87
1.5
1.9
4.87
15.77
e6/l
1.95
60
275
176
1035
1.78
10.83
4.3
6.5
23.91
23.90
mmol/l
0.02
170
1027
106
532
2.05
10.53
7.7
5.3
1.80
1.58
%
1.10
99
502
83
379
2.25
10.48
1.5
1.9
834.83
1359.25
e6/l
0.23
65
292
81
368
2.26
10.36
8.5
6.2
1.53
1.25
mmol/l
1.36
68
320
88
416
2.17
10.22
1.3
1.8
501.01
488.98
mg/l
0.05
82
401
1595
14867
1.65
10.13
21.6
14.7
3.97
3.94
mmol/l
3.30
1560
14540
590
4627
1.41
10.01
6.8
6.2
—
—
—
0
0
527
6649
0.71
9.88
2.8
2.7
—
—
—
0
0
222
1441
1.62
9.44
2.8
2.5
34.00
73.09
u/l
0.60
198
1205
89
437
2.09
9.40
2.6
1.9
1.03
1.92
ug/l
0.65
76
386
58
241
2.45
9.10
4.4
3.9
2.34
2.33
mmol/l
0.01
40
149
1112
9776
1.36
8.86
5.3
4.2
428.08
1737.56
e6/l
1.32
24
131
57
239
2.43
8.78
10.3
7.7
11.46
11.41
mmol/l
0.03
52
219
57
240
2.42
8.70
10.3
7.6
103.65
105.31
mmol/l
1.41
52
220
207
1348
1.61
8.67
2.3
2.8
0.22
0.22
g/l
0.30
199
1272
100
530
1.94
8.57
2.5
2.8
—
—
—
0
0
364
2682
1.45
8.53
2.8
2.9
544.94
541.08
mosm/kgh2o
0.11
325
2364
460
3547
1.40
8.34
1.8
2.0
1.25
1.06
mg/l
0.29
344
2677
275
1926
1.51
8.32
5.8
7.5
1.11
1.09
mmol/l
0.32
256
1809
810
6842
1.34
8.14
2.8
2.6
73.76
73.73
nmol/l
0.01
742
6401
126
2055
0.58
7.84
1.2
1.3
—
—
—
0
0
497
3935
1.36
7.55
2.3
2.4
2.63
2.66
mg/l
0.13
422
3438
220
1500
1.53
7.53
3.3
3.5
1.81
1.71
%
0.84
197
1370
33
115
2.90
7.34
2.8
2.0
—
—
—
0
0
173
1123
1.60
7.34
3.9
3.9
7.37
7.35
ph
0.93
142
837
461
3637
1.36
7.10
4.2
3.5
1.02
1.86
kg/l
0.80
329
2386
127
770
1.70
7.04
8.0
12.4
1.31
1.33
%
0.08
127
764
234
1647
1.48
6.87
1.9
2.2
379.58
371.68
nmol/l
0.23
219
1546
71
364
1.99
6.75
3.0
3.0
6.47
3.32
index
0.67
38
200
43
181
2.41
6.64
1.8
2.2
—
—
—
0
0
1359
14484
0.75
6.29
4.6
4.4
1.46
1.45
mmol/l
0.66
1279
13756
1380
14659
0.75
6.06
5.2
4.9
2.77
2.79
mmol/l
0.24
1303
13936
499
4068
1.31
6.00
3.6
3.1
—
1.00
—
0
8
263
1942
1.42
5.97
3.7
3.2
3.78
4.80
e9/l
2.24
230
1743
812
7058
1.27
5.92
11.1
10.6
0.00
0.00
e9/l
0.67
637
5720
128
816
1.61
5.88
2.9
3.0
119.47
165.85
ng/l
1.13
118
732
128
820
1.60
5.77
5.0
6.3
—
—
—
0
0
136
886
1.58
5.71
2.8
2.8
—
—
—
0
0
88
516
1.74
5.55
1.7
2.1
1.25
1.39
g/l
0.69
79
466
398
3182
1.32
5.44
2.9
3.3
713.07
1135.17
ng/l
3.14
329
2665
151
1021
1.52
5.38
3.9
5.0
84.60
80.16
ng/l
0.20
127
930
547
4573
1.28
5.33
3.3
3.4
59.77
65.48
e6/l
0.07
437
3424
49
241
2.06
5.28
2.6
2.5
16.56
16.65
%
0.09
49
236
1280
13671
0.78
5.26
3.9
3.8
1.33
1.26
mmol/l
2.16
1201
12920
1375
14545
0.77
5.16
4.7
4.5
4.70
4.68
mmol/l
0.48
1302
13884
159
1097
1.49
5.16
2.8
3.4
68.46
70.63
e9/l
0.31
117
775
242
1814
1.39
5.02
1.8
1.7
—
—
—
0
0
144
984
1.50
4.90
2.1
2.1
—
—
—
0
0
303
2371
1.33
4.76
2.5
2.6
13.46
14.17
umol/l
0.97
285
2234
117
1731
0.65
4.75
1.5
1.6
3.60
3.45
mmol/l
0.71
75
1144
445
3673
1.28
4.72
4.6
4.4
95.35
91.92
%
2.50
437
3592
57
310
1.87
4.65
2.2
2.4
130.68
132.12
g/l
0.25
50
258
259
1987
1.35
4.64
2.5
2.7
23.33
23.81
%
0.22
240
1873
640
5523
1.25
4.64
4.0
4.0
60.17
81.30
e6/l
0.52
453
3676
40
192
2.11
4.63
1.3
2.5
—
—
—
0
0
53
283
1.90
4.58
4.2
3.8
—
—
—
0
0
123
828
1.52
4.51
1.7
1.7
0.26
0.30
mg/l
0.59
53
381
282
2201
1.33
4.50
2.5
2.6
2.36
2.40
g/l
0.52
264
2056
110
730
1.54
4.32
5.1
6.3
24.09
24.43
mmol/l
0.72
104
705
50
268
1.89
4.29
3.2
3.9
90.46
90.48
%
0.01
50
258
163
1175
1.43
4.24
2.3
2.4
6642.87
6618.29
u/l
0.00
67
488
167
2262
0.71
4.23
1.7
1.8
3.63
3.48
ratio
0.70
123
1671
63
366
1.75
4.18
4.1
4.0
1.37
1.37
mmol/l
0.00
63
357
327
2642
1.29
4.05
1.7
1.7
453.16
40915457.58
pmol/l
3.28
280
2295
256
2002
1.33
4.03
2.1
2.0
—
—
—
0
0
147
2015
0.71
4.00
2.8
2.9
0.70
0.76
ug/l
0.36
96
1129
1189
11058
1.22
3.90
4.3
3.3
54.90
40.55
u/l
5.84
1152
10626
288
2304
1.30
3.84
2.8
3.1
5.73
2.66
e6/l
2.03
152
1105
167
1238
1.38
3.72
2.2
2.0
—
—
—
0
0
82
530
1.57
3.66
1.1
1.1
2.06
5.58
eliau/ml
1.06
13
79
157
1156
1.39
3.65
2.3
2.1
—
—
—
0
0
167
1244
1.38
3.62
2.2
2.0
—
—
—
0
0
11
25
4.42
3.62
1.6
1.2
—
—
—
0
0
167
1248
1.37
3.55
2.2
2.0
—
—
—
0
0
35
178
1.99
3.54
1.4
1.2
—
—
—
0
0
166
1240
1.37
3.54
7.9
9.7
7.84
8.19
mmol/l
0.28
158
1198
371
3092
1.25
3.54
2.7
2.7
8.89
6.45
e6/l
1.30
339
2807
99
673
1.50
3.53
1.8
2.0
7.38
7.52
iu/ml
0.02
21
160
133
961
1.41
3.46
4.1
3.7
1.21
1.23
mmol/l
2.42
121
816
534
4641
1.21
3.41
3.7
3.7
7.71
8.11
mmol/l
1.00
459
4082
164
1231
1.37
3.40
2.2
2.0
—
—
—
0
0
145
1070
1.39
3.34
2.4
2.5
0.46
0.38
e6/l
0.13
140
1016
59
362
1.65
3.28
4.0
6.9
64.16
64.51
%
0.04
54
352
72
469
1.56
3.15
1.4
1.3
9.22
2.50
u/ml
—
5
35
72
469
1.56
3.15
1.4
1.3
27.92
8.70
u/ml
0.60
11
63
459
3959
1.21
3.14
3.2
3.3
0.36
0.32
e6/l
0.31
358
2829
291
2394
1.26
3.10
1.4
1.4
641.51
471.44
titre
0.50
53
472
147
1103
1.36
3.08
2.3
2.4
14.73
21.42
au/ml
—
10
144
17
68
2.51
3.04
1.9
2.8
7.57
8.29
mmol/l
0.58
17
68
1573
15200
1.28
3.02
19.8
13.4
22.39
21.93
mg/l
0.23
1354
12266
53
840
0.62
3.01
1.1
1.1
0.86
0.89
g/l
0.34
53
840
24
113
2.14
3.01
1.3
1.1
—
—
—
0
0
1632
15853
1.32
2.96
13.5
10.7
25.46
26.59
u/l
2.00
1590
15496
1286
12185
1.20
2.92
5.1
4.4
14.04
14.53
pmol/l
10.58
1207
11401
136
1020
1.36
2.87
1.3
1.3
71.24
47.83
au/ml
—
5
65
29
150
1.95
2.85
1.1
1.2
29.27
40.38
mg/l
1.13
23
121
25
123
2.05
2.82
1.3
1.2
0.56
0.62
ratio
0.47
19
73
20
90
2.24
2.80
1.5
2.7
2.14
1.82
u/field
0.17
14
55
119
878
1.38
2.79
1.9
2.2
7.08
7.67
ug/l
0.07
99
790
9
23
3.93
2.77
1.2
1.8
—
—
—
0
0
53
822
0.63
2.76
1.0
1.1
1.53
1.52
g/l
0.06
53
822
293
2450
1.23
2.69
2.4
2.7
2.42
2.43
mmol/l
0.41
265
2197
76
523
1.47
2.62
1.7
1.8
0.21
0.23
g/l
1.51
67
496
10
30
3.35
2.60
1.0
1.2
—
—
—
0
0
503
4443
1.18
2.60
1.5
1.4
2.07
1.58
u/ml
0.36
118
1208
544
4837
1.18
2.60
2.6
2.4
—
—
—
0
0
7
15
4.68
2.59
1.0
1.3
—
—
—
0
0
225
1839
1.26
2.54
1.5
1.5
—
—
—
0
0
51
324
1.59
2.53
3.2
3.7
47.63
65.08
mg/l
0.40
43
273
51
324
1.59
2.53
3.1
3.7
32.63
38.72
mg/l
0.37
44
274
114
851
1.36
2.51
1.9
1.9
—
—
—
0
0
1462
14077
1.21
2.50
6.2
5.2
1.86
1.82
mu/l
0.57
1391
13326
291
2452
1.22
2.49
2.7
2.9
1.23
1.17
e6/l
0.08
157
1247
883
8173
1.16
2.49
4.2
3.6
10.71
5.78
estimate
0.18
188
1654
34
195
1.76
2.47
1.2
1.5
39.89
129.36
mu/l
0.96
28
175
166
1318
1.29
2.39
2.0
2.0
0.00
0.02
estimate
0.78
43
307
161
1274
1.29
2.38
5.5
5.0
0.87
0.93
%
0.11
60
374
8
22
3.65
2.36
1.8
1.3
—
—
—
0
0
192
1556
1.26
2.35
1.2
1.2
—
—
—
0
0
727
6657
1.15
2.33
3.5
3.2
6.46
6.20
ph
7.48
418
3800
34
201
1.70
2.25
3.3
3.7
1.26
1.53
%
0.19
29
186
82
593
1.40
2.22
2.3
1.7
—
—
—
0
0
19
93
2.05
2.21
1.2
1.4
225871.54
24133.43
e6/l
0.79
13
51
76
543
1.42
2.20
1.7
1.7
1.14
1.19
g/l
0.57
67
514
287
2450
1.20
2.16
1.7
1.7
—
—
—
0
0
78
1065
0.72
2.15
1.4
1.6
—
—
—
0
0
34
204
1.68
2.15
1.6
1.6
—
—
—
0
0
437
3876
1.17
2.11
1.5
1.5
2.31
2.18
g/l
0.49
254
2474
83
608
1.38
2.10
2.4
2.3
—
—
—
0
0
91
677
1.36
2.09
1.3
1.2
0.20
1.31
u/ml
—
6
49
44
285
1.56
2.07
3.1
3.6
1.83
2.53
ratio
0.43
22
161
29
169
1.73
2.04
2.1
3.5
—
—
—
0
0
6
15
4.01
2.04
1.0
1.2
—
—
—
0
0
879
8208
1.14
2.03
4.2
3.6
0.00
0.20
estimate
0.54
177
1577
26
147
1.78
2.03
3.7
4.0
—
—
—
0
0
29
170
1.72
2.00
7.1
6.1
10.82
10.77
mg/l
0.02
24
157
26
148
1.77
1.99
1.4
2.2
—
—
—
0
0
150
1207
1.26
1.98
3.5
2.2
6.32
6.14
ph
1.48
102
777
152
1226
1.26
1.97
5.3
4.8
0.65
0.65
%
0.01
59
356
212
1774
1.22
1.96
2.6
3.5
5.58
7.26
umol/l
1.12
177
1533
42
273
1.55
1.96
4.1
4.0
—
—
—
0
0
152
1864
0.80
1.93
1.3
1.3
—
—
—
0
0
13
58
2.25
1.91
1.9
1.3
—
—
—
0
0
92
698
1.34
1.89
2.0
2.1
0.07
1.02
estimate
0.46
29
249
5
12
4.18
1.82
1.6
1.1
45.98
39.86
nmol/l
—
5
12
5
12
4.18
1.82
1.2
1.2
—
—
—
0
0
159
1309
1.24
1.74
3.1
3.0
10.92
10.36
g/l
0.93
151
1228
525
5742
0.88
1.73
2.1
2.0
—
—
—
0
0
22
125
1.77
1.72
4.1
3.5
15.00
13.86
index
0.10
15
94
17
89
1.92
1.70
1.1
1.4
—
—
—
0
0
1014
9624
1.12
1.67
3.7
3.4
—
29431.21
—
0
14
170
1417
1.22
1.67
1.3
1.3
129.41
138.00
u/ml
0.10
60
548
42
286
1.48
1.63
1.9
1.6
619.57
353.02
mu/l
1.20
35
241
83
637
1.32
1.61
3.2
3.0
1.02
1.02
ratio
0.75
71
590
860
8097
1.12
1.61
4.2
3.6
0.00
0.00
estimate
0.50
186
1645
150
1241
1.23
1.59
5.7
5.4
0.16
0.41
%
0.43
43
297
148
1223
1.23
1.59
5.8
5.1
0.23
0.11
%
0.48
48
319
1657
16816
0.81
1.56
30.4
20.3
6.73
6.76
e9/l
0.18
1629
16486
295
3333
0.86
1.55
3.9
4.7
1.67
2.13
ug/l
1.57
268
3035
64
476
1.36
1.54
1.1
1.4
80.00
90.18
titre
—
5
55
751
7032
1.12
1.53
3.1
2.8
—
—
estimate
—
0
0
1658
16819
0.81
1.49
30.5
20.4
134.29
136.35
g/l
7.85
1647
16689
36
243
1.49
1.47
1.6
2.0
—
1010.91
—
0
11
89
1122
0.78
1.47
1.4
1.4
—
—
—
0
0
22
354
0.62
1.46
1.2
1.3
—
—
—
0
0
220
1904
1.18
1.46
1.3
1.2
—
—
—
0
0
9
38
2.38
1.45
5.4
2.1
1.09
1.23
umol/l
—
9
28
131
1080
1.23
1.45
2.9
3.7
4.51
4.67
pmol/l
1.23
116
977
115
935
1.25
1.45
1.3
1.2
—
—
—
0
0
1658
16812
0.82
1.42
30.3
20.3
4.45
4.56
e12/l
15.79
1630
16494
1658
16811
0.82
1.41
30.8
20.8
39.92
41.18
%
2.89
1648
16672
1658
16811
0.82
1.41
30.2
20.2
30.35
30.10
pg
6.77
1648
16682
1623
15939
1.19
1.39
22.1
15.8
70.26
72.96
umol/l
2.08
1606
15773
13
67
1.95
1.38
4.5
2.6
2.96
2.67
mmol/l
0.27
13
59
1658
16808
0.82
1.38
30.2
20.2
90.48
90.07
fl
3.10
1648
16681
6
23
2.61
1.37
1.0
1.0
64.00
72.35
titre
—
6
23
402
3652
1.13
1.36
2.5
2.4
—
—
—
0
0
5
17
2.95
1.36
2.2
3.3
0.30
0.20
%
—
5
17
78
611
1.29
1.35
1.5
1.3
—
—
—
0
0
1658
16803
0.83
1.33
30.4
20.3
249.69
257.28
e9/l
5.46
1631
16518
12
61
1.97
1.33
1.4
1.7
—
—
—
0
0
40
283
1.42
1.32
1.1
1.3
2.38
5.34
u/ml
1.87
16
134
6
24
2.50
1.30
1.0
1.1
—
—
—
0
0
9
43
2.10
1.30
1.0
1.1
—
—
—
0
0
9
43
2.10
1.30
1.0
1.1
—
—
—
0
0
9
43
2.10
1.30
1.0
1.1
—
—
—
0
0
420
3838
1.12
1.29
5.3
4.7
—
—
—
0
0
8
34
2.36
1.29
2.3
1.5
41.25
41.32
g/l
—
8
34
13
69
1.89
1.28
3.4
1.7
107.88
105.30
ng/l
0.04
13
69
35
243
1.45
1.28
1.2
1.6
50.03
23.67
ng/l
0.49
35
243
8
35
2.29
1.27
1.4
1.4
6.62
11.45
mmol/l
—
8
35
85
681
1.26
1.25
2.0
3.3
20.67
20.89
s
0.23
79
619
21
131
1.61
1.23
1.1
1.2
—
—
—
0
0
9
45
2.00
1.23
2.8
2.2
—
—
—
0
0
20
124
1.62
1.21
1.1
1.0
—
—
—
0
0
39
281
1.40
1.19
6.0
3.6
19.33
26.24
mg/l
1.20
28
200
12
64
1.88
1.18
1.1
1.2
—
—
—
0
0
16
94
1.71
1.17
1.6
1.2
—
105.80
—
0
5
28
190
1.48
1.16
1.0
1.2
2.00
4.08
u/ml
—
10
88
67
527
1.28
1.15
1.3
1.3
—
—
—
0
0
18
110
1.64
1.15
1.2
1.3
—
—
—
0
0
8
39
2.06
1.15
7.4
7.9
4.42
5.09
kpa
—
8
39
5
20
2.50
1.15
1.2
3.1
—
—
—
0
0
5
20
2.50
1.15
1.6
1.9
—
—
—
0
0
30
208
1.45
1.13
2.0
2.4
—
—
—
0
0
7
30
2.34
1.12
2.7
3.3
11.57
5.86
ug/l
—
7
30
21
135
1.56
1.11
1.0
1.0
—
—
—
0
0
502
4671
1.10
1.10
3.3
2.8
0.00
0.03
0.49
14
71
52
398
1.32
1.10
1.4
1.3
—
6.90
—
0
6
16
96
1.67
1.10
2.4
2.5
—
—
—
0
0
41
303
1.36
1.09
1.0
1.1
—
—
—
0
0
42
313
1.35
1.07
1.1
1.1
—
—
—
0
0
16
254
0.63
1.06
1.5
1.6
—
—
—
0
0
65
516
1.27
1.06
1.4
1.3
—
—
—
0
0
69
553
1.26
1.04
2.6
5.1
358.94
327.79
mg/l
0.11
34
286
5
22
2.28
1.03
2.2
2.0
—
—
—
0
0
461
4295
1.10
0.99
4.3
3.6
0.00
0.01
estimate
1.94
171
1555
42
318
1.33
0.98
1.1
1.1
2.59
2.35
eliau/ml
0.11
16
142
10
54
1.86
0.96
1.0
1.5
67.00
82.44
nmol/24h
—
10
54
12
69
1.74
0.96
1.5
3.9
88.80
49.95
umol/l
—
5
13
41
311
1.33
0.95
1.1
1.1
52.00
1665.93
iu/ml
—
8
81
408
3786
1.10
0.95
1.8
1.8
—
—
—
0
0
13
77
1.69
0.95
1.1
1.5
147.85
143.22
nmol/l
0.10
13
77
17
109
1.56
0.93
1.1
1.0
—
—
—
0
0
37
278
1.34
0.92
2.9
3.5
9.39
7.71
pmol/l
0.27
37
278
62
500
1.25
0.92
1.9
2.2
2.54
3.96
iu/l
2.80
20
219
114
978
1.18
0.91
1.7
1.7
307.83
294.68
mu/l
0.22
102
887
15
94
1.60
0.90
4.8
3.9
0.33
0.84
index
2.73
15
94
11
63
1.75
0.90
3.9
3.2
15.12
16.51
%
1.07
11
63
651
6183
1.08
0.89
4.2
3.4
0.02
0.05
estimate
0.46
153
1381
56
694
0.80
0.88
1.4
1.5
1.20
1.27
mm
0.54
42
506
496
4660
1.09
0.88
3.6
2.9
0.02
0.07
estimate
0.50
145
1345
408
3801
1.09
0.88
3.9
3.6
73.50
57.38
mg/l
0.62
287
2531
54
432
1.26
0.86
1.3
1.4
291.25
302.22
ug/g
0.16
32
245
11
64
1.72
0.86
1.2
1.2
—
—
—
0
0
182
1625
1.13
0.86
1.5
1.5
—
—
—
0
0
6
112
0.53
0.83
1.3
1.4
185.50
162.62
pmol/l
—
6
112
26
188
1.39
0.83
1.2
1.3
0.57
9.96
nmol/l
0.50
26
181
21
146
1.44
0.82
1.7
2.1
1.18
0.91
%
0.82
13
86
413
3863
1.09
0.82
4.6
4.3
13.22
14.01
mg/mmol
0.05
281
2521
58
708
0.81
0.81
1.3
1.5
—
—
—
0
0
1308
13362
0.92
0.81
6.1
5.3
38.30
38.05
mmol/mol
0.38
1232
12750
143
1613
0.88
0.79
1.5
1.6
1083.12
999.40
mu/l
0.40
122
1366
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
17.88
—
0
8
0
26
0.00
0.78
0.0
1.2
—
26.71
—
0
7
1368
13410
1.08
0.77
24.6
16.4
13.28
13.39
%
3.22
1354
13246
20
140
1.43
0.77
1.9
2.8
1.34
1.34
g/24h
—
10
92
121
1061
1.15
0.76
1.2
1.2
—
—
—
0
0
23
166
1.39
0.75
1.2
1.4
2.82
3.95
u/ml
0.23
13
98
12
75
1.60
0.75
2.3
3.3
—
—
—
0
0
23
167
1.38
0.73
1.0
1.1
0.06
4.85
u/ml
—
7
56
23
167
1.38
0.73
1.2
1.3
—
—
nmol/l
—
0
0
5
25
2.00
0.72
1.4
2.2
1.90
2.66
%
—
5
25
9
56
1.61
0.72
4.8
2.3
27.11
29.36
%
—
9
56
10
60
1.67
0.72
1.2
1.3
—
—
—
0
0
17
240
0.71
0.70
2.0
1.4
—
—
—
0
0
115
1013
1.14
0.69
1.6
1.9
1.51
1.28
g/l
0.68
106
953
39
310
1.26
0.69
1.4
1.3
14.79
19.96
u/l
0.65
26
266
14
93
1.51
0.69
35.9
45.4
7.18
7.10
ug/l
0.05
14
83
36
453
0.79
0.69
2.7
3.7
87.85
3302.25
u/ml
0.84
30
390
32
248
1.30
0.69
1.4
2.0
4.49
5.19
mmol/24h
0.64
26
225
61
723
0.84
0.67
1.4
1.6
—
—
—
0
0
7
43
1.63
0.67
1.3
1.2
—
—
—
0
0
78
905
0.86
0.66
1.1
1.1
—
—
—
0
0
183
2007
0.90
0.66
1.8
1.9
—
—
—
0
0
5
28
1.79
0.66
1.4
3.5
—
—
—
0
0
18
129
1.40
0.63
2.2
1.7
55.00
58.00
%
0.12
12
89
17
121
1.41
0.62
3.2
1.7
12.05
23.91
umol/l
4.38
17
113
387
3655
1.07
0.62
3.9
3.5
0.00
0.20
—
7
30
139
1253
1.12
0.61
1.4
1.5
24.08
22.07
iu/l
0.34
118
1033
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
2.7
—
3586.00
—
0
22
12
174
0.69
0.59
1.1
1.2
—
—
—
0
0
8
54
1.48
0.57
1.0
2.9
66.25
93.66
ug/l
—
8
54
295
2769
1.08
0.56
1.3
1.3
9.42
10.05
u/ml
0.06
103
1135
11
73
1.51
0.56
1.1
1.5
0.12
2.00
u/ml
2.76
11
73
12
171
0.70
0.54
3.6
4.8
167.62
53.13
u/ml
—
6
56
54
459
1.18
0.54
1.2
1.2
—
—
—
0
0
281
2989
0.93
0.53
2.0
1.9
—
—
—
0
0
48
405
1.19
0.53
2.2
3.1
5.62
6.91
umol/l
0.44
40
308
6
39
1.54
0.53
1.2
1.0
6.21
6.56
mg/g
—
6
39
23
178
1.30
0.53
1.3
1.3
—
—
—
0
0
23
179
1.29
0.51
1.3
1.3
2.89
2.87
g/l
0.02
17
133
23
179
1.29
0.51
1.3
1.3
0.36
0.40
g/l
0.36
17
133
23
179
1.29
0.51
1.3
1.3
8.73
6.38
g/l
1.10
17
135
318
3007
1.07
0.50
1.3
1.3
24.76
25.10
iu/ml
0.02
99
864
492
5123
0.95
0.49
1.6
1.7
—
—
—
0
0
19
145
1.31
0.48
3.0
2.2
33.53
32.60
pg
0.55
19
145
372
3545
1.06
0.47
2.6
2.7
319.45
332.06
umol/l
1.59
325
3226
21
164
1.28
0.46
1.1
1.3
0.17
0.29
nmol/l
0.46
15
121
94
1040
0.90
0.44
1.5
1.5
—
—
—
0
0
5
31
1.61
0.43
1.0
1.1
0.25
2.07
u/ml
—
5
21
160
1486
1.08
0.42
4.6
4.1
32.52
31.37
%
0.62
116
1075
74
827
0.89
0.42
1.4
1.3
282.15
225.11
miu/ml
0.74
36
409
12
87
1.38
0.42
2.4
1.6
37.29
32.78
%
—
7
55
8
57
1.41
0.42
1.1
1.4
29.13
28.26
s
—
8
57
47
407
1.16
0.41
1.1
1.1
0.13
0.29
u/ml
0.96
16
149
83
919
0.90
0.41
1.4
1.6
61.47
60.38
ug/l
0.08
69
780
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
8
61
1.31
0.39
1.0
1.1
43.63
41.48
iu/ml
—
8
61
7
104
0.67
0.39
1.1
1.1
—
1.31
—
0
17
65
579
1.13
0.39
1.1
1.1
4.88
6.27
u/ml
0.31
32
356
9
67
1.34
0.38
1.3
1.4
—
—
—
0
0
9
67
1.34
0.38
1.3
2.5
—
—
—
0
0
141
1312
1.08
0.37
1.4
1.3
143.64
236.38
u/ml
1.41
122
1222
24
198
1.21
0.36
1.8
2.0
—
—
—
0
0
23
189
1.22
0.36
1.0
1.3
0.94
3.71
u/ml
—
6
74
6
42
1.43
0.35
1.2
1.0
—
—
—
0
0
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
65
584
1.12
0.35
1.3
1.2
—
—
—
0
0
36
310
1.16
0.35
1.7
2.1
—
19.33
—
0
6
5
80
0.62
0.35
2.4
4.3
—
36.45
—
0
16
86
785
1.10
0.35
1.4
1.6
8.29
8.44
u/l
0.04
69
608
14
108
1.30
0.35
2.0
3.3
29.43
27.22
umol/l
0.59
14
99
29
246
1.18
0.34
1.3
1.6
—
—
—
0
0
29
246
1.18
0.34
1.3
1.6
—
—
—
0
0
29
246
1.18
0.34
1.3
1.6
—
—
—
0
0
29
246
1.18
0.34
1.3
1.6
—
—
—
0
0
47
415
1.14
0.34
1.4
1.6
—
—
—
0
0
18
145
1.24
0.33
1.1
1.4
1.81
1.49
nmol/l
0.82
18
133
6
46
1.31
0.33
2.7
2.3
11.95
1.97
ug/l
—
6
38
6
90
0.67
0.32
1.3
1.1
111.67
199.95
iu/ml
—
6
90
31
266
1.17
0.32
5.7
4.0
4.25
4.06
e9/l
0.15
31
266
25
295
0.85
0.32
1.3
1.1
—
—
—
0
0
17
137
1.24
0.32
3.8
2.2
23.08
31.98
mg/l
0.47
12
89
20
241
0.83
0.31
1.0
1.1
—
—
—
0
0
14
110
1.27
0.31
1.1
1.2
—
—
—
0
0
17
138
1.23
0.30
1.2
1.2
—
—
—
0
0
133
1251
1.07
0.29
3.8
3.5
—
—
—
0
0
17
205
0.83
0.28
1.2
1.1
21.10
17.07
u/ml
—
8
78
134
1419
0.94
0.27
2.6
2.3
11.13
12.67
nmol/l
1.34
117
1312
42
468
0.89
0.26
1.1
1.1
—
—
—
0
0
42
468
0.89
0.26
1.1
1.1
—
—
—
0
0
44
395
1.12
0.26
1.5
1.6
108.89
139.33
au/ml
—
9
126
34
300
1.14
0.26
1.5
1.7
0.74
0.77
g/l
0.07
25
241
13
104
1.25
0.26
1.1
1.1
1662.08
1528.81
miu/ml
0.17
13
104
29
253
1.15
0.26
1.2
1.2
—
—
—
0
0
47
424
1.11
0.26
1.1
1.1
4.65
6.87
u/ml
0.28
23
204
26
225
1.16
0.26
1.2
1.3
—
—
—
0
0
61
561
1.09
0.24
1.1
1.1
0.37
1.18
u/ml
1.94
29
284
16
134
1.20
0.23
1.1
1.1
119.75
110.74
pmol/l
0.26
16
134
84
788
1.07
0.21
1.0
1.1
—
—
—
0
0
5
42
1.19
0.21
1.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
162.09
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
595
6061
0.97
0.21
2.0
1.9
1.44
1.37
mmol/l
0.98
519
5332
0
12
0.00
0.21
0.0
2.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
11.00
—
0
7
49
450
1.09
0.21
1.1
1.1
4.12
5.91
u/ml
0.22
29
242
0
13
0.00
0.21
0.0
10.5
—
70.13
—
0
8
1367
13766
0.97
0.20
4.7
4.2
5.78
5.76
mmol/l
0.18
1281
12899
6
48
1.25
0.20
1.5
1.1
—
—
—
0
0
11
133
0.83
0.19
1.0
1.6
9.62
11.45
umol/l
0.44
11
122
6
51
1.18
0.19
1.2
2.0
—
—
—
0
0
6
52
1.15
0.19
1.0
1.5
16.33
18.06
umol/l
—
6
44
37
405
0.91
0.18
1.1
1.1
12.81
15.01
au/ml
—
7
103
13
109
1.19
0.18
1.2
1.2
—
—
—
0
0
7
61
1.15
0.17
1.0
1.6
0.00
0.05
estimate
—
7
61
37
339
1.09
0.17
1.3
1.2
—
—
—
0
0
41
378
1.09
0.17
5.1
3.6
58.02
56.69
%
0.24
41
378
13
111
1.17
0.15
2.2
1.5
0.48
0.50
e9/l
0.07
13
111
255
2489
1.03
0.14
2.1
2.9
122.51
107.01
ug/g
0.28
200
2015
17
151
1.13
0.13
2.8
3.2
—
—
—
0
0
17
190
0.89
0.13
1.2
1.2
—
—
—
0
0
41
437
0.94
0.12
1.3
1.5
0.33
0.43
nmol/l
0.33
33
355
12
137
0.88
0.12
1.0
1.0
—
—
—
0
0
108
1117
0.96
0.11
4.4
4.5
14.75
21.07
ug/l
0.27
87
889
66
631
1.05
0.11
1.7
1.7
10.49
7.91
u/ml
0.22
13
162
30
322
0.93
0.11
1.2
1.2
—
—
—
0
0
14
157
0.89
0.11
1.1
1.1
—
—
—
0
0
40
378
1.06
0.10
1.9
2.5
—
—
—
0
0
58
556
1.04
0.09
1.2
1.1
2.46
2.03
u/ml
0.09
30
317
38
360
1.06
0.09
2.7
2.4
1.10
0.83
nmol/l
1.19
33
312
6
56
1.07
0.08
1.3
2.7
—
—
—
0
0
12
107
1.12
0.08
1.2
1.1
—
—
—
0
0
7
66
1.06
0.08
4.4
4.0
—
—
—
0
0
6
70
0.86
0.07
8.3
5.7
12.67
8.33
%
—
6
70
6
70
0.86
0.07
4.2
2.8
41.67
44.13
%
—
6
70
19
176
1.08
0.07
2.0
2.2
—
—
—
0
0
16
147
1.09
0.07
1.2
1.2
—
—
—
0
0
9
85
1.06
0.07
1.4
1.1
—
—
—
0
0
57
551
1.04
0.07
1.2
1.1
—
—
—
0
0
33
345
0.96
0.06
2.0
1.8
—
—
—
0
0
840
8360
1.01
0.06
3.4
3.3
113.34
94.48
ug/l
1.02
795
7974
65
632
1.03
0.06
1.2
1.2
2.33
2.60
u/ml
0.09
34
363
11
121
0.91
0.06
1.2
1.1
—
—
—
0
0
466
4633
1.01
0.04
2.4
2.2
—
—
—
0
0
17
160
1.06
0.04
1.2
1.4
—
—
—
0
0
12
129
0.93
0.03
1.2
1.2
—
—
—
0
0
16
152
1.05
0.02
1.9
3.3
160.70
205.37
e6/l
—
10
119
88
869
1.01
0.02
1.4
1.4
—
—
—
0
0
11
103
1.07
0.02
1.5
1.6
—
—
—
0
0
165
1641
1.01
0.01
1.3
1.4
—
—
—
0
0
32
327
0.98
0.01
1.9
1.7
7646.61
11475.58
e6/l
0.59
23
231
16
166
0.96
0.00
1.3
1.6
601.68
811.33
pmol/l
—
5
22
35
344
1.02
0.00
1.0
1.1
—
—
—
0
0
10
105
0.95
0.00
2.3
2.8
43.00
44.60
%
—
5
54
10
105
0.95
0.00
1.4
1.4
66.10
75.72
umol/l
—
10
105
11
109
1.01
0.00
1.1
1.1
—
—
—
0
0
15
151
0.99
0.00
2.1
3.2
330.44
512.39
e6/l
—
9
113
42
415
1.01
0.00
9.7
9.3
—
—
—
0
0
11
106
1.04
0.00
3.1
2.6
—
—
—
0
0
26
264
0.98
0.00
2.7
2.4
73.53
113.38
ug/min
0.31
15
166
12
122
0.98
0.00
1.9
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
0.57
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
1300.40
—
0
5
0
9
0.00
-0.00
0.0
2.4
—
195.33
—
0
9
9
94
0.96
-0.00
2.8
1.4
8.67
6.98
u/l
—
9
79
0
5
0.00
-0.00
0.0
3.0
—
2.02
—
0
5
6
62
0.97
-0.00
1.2
1.1
—
—
—
0
0
7
74
0.95
-0.00
1.1
1.3
171.79
176.88
mmol/24h
—
7
74
6
63
0.95
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
0.55
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.0
—
407.86
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
3.46
—
0
6
6
66
0.91
-0.00
1.2
1.3
—
96.00
—
0
47
0
7
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
48
480
1.00
-0.00
1.3
1.5
265.38
222.01
u/ml
0.39
24
277
20
200
1.00
-0.00
3.4
4.2
5100.70
308.00
u/ml
0.45
20
186
0
6
0.00
-0.00
0.0
1.0
—
1585.83
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
77
0.91
-0.00
1.1
2.0
—
—
—
0
0
9
94
0.96
-0.00
1.0
1.0
7.35
8.95
mu/l
—
9
85
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint GE and mortality.

Females

Parameter HR [95% CI] p-value
GE 3.087 [2.71, 3.52] < 0.001
Birth year 0.994 [0.99, 1.0] 0.17

During the follow-up period (1.1.1998 — 31.12.2019), 687 out of 6796 females with GE died.

Males

Parameter HR [95% CI] p-value
GE 2.745 [2.43, 3.11] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 870 out of 5793 males with GE died.

Mortality risk

Mortality risk for people of age

years, who have GE.

N-year risk Females Males
1 0.297% 0.461%
5 1.675% 3.273%
10 4.035% 7.686%
15 8.089% 14.45%
20 13.76% 22.713%

Relationships between endpoints

Index endpoint: GE – Generalized epilepsy

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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