Pustulosis palmaris et plantaris

L12_PSORI_PUSTUPALM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L40.3
  • Hospital discharge: ICD-9 6961D
  • Hospital discharge: ICD-8 68693
  • Cause of death: ICD-10 L40.3
  • Cause of death: ICD-9 6961D
  • Cause of death: ICD-8 68693

2 out of 7 registries used, show all original rules.

1834

4. Check minimum number of events

None

1834

5. Include endpoints

None

1834

6. Filter based on genotype QC (FinnGen only)

1658

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L40
Name in latin
Pustulosis palmaris et plantaris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9805 6825 2953
Only index persons 9263 6578 2685
Unadjusted period prevalence (%)
Whole population 0.16 0.20 0.08
Only index persons 0.20 0.24 0.10
Median age at first event (years)
Whole population 51.84 53.06 49.05
Only index persons 51.55 52.89 48.26

-FinnGen-

Key figures

All Female Male
Number of individuals 1658 1199 459
Unadjusted period prevalence (%) 0.37 0.43 0.21
Median age at first event (years) 53.77 53.83 53.60

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1726
Matched controls
17260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D07AC01
ATC
betamethasone; topical
6.5
313.3
1194
4407
D07AD01
ATC
clobetasol; topical
23.2
307.7
1251
1757
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
11642.7
307.7
1656
35
D05AX02
ATC
calcipotriol; topical
36.1
307.7
341
117
D05BB02
ATC
acitretin; oral
116.6
307.7
456
53
L40.0
ICD-10 Finland
Psoriasis vulgaris
77.0
307.7
336
54
D05AX52
ATC
calcipotriol, combinations; topical
34.9
307.7
524
213
D07XC01
ATC
betamethasone; topical
9.7
307.7
646
1007
E0000UV, ,
ATC
6.9
301.5
1297
5265
L04AX03
ATC
methotrexate; systemic
7.4
276.9
485
862
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
129.9
261.6
132
11
D05AX03
ATC
calcitriol; topical
76.1
260.2
140
20
E000003, ,
ATC
10.8
249.4
293
321
D07BC01
ATC
betamethasone and antiseptics; topical
6.3
247.6
527
1128
D07AC13
ATC
mometasone; topical
5.0
244.3
954
3407
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
378.7
201.2
199
6
TQW80
NOMESCO Finland
Local dermatologic skincare
12.8
179.1
181
157
L40.9
ICD-10 Finland
Psoriasis, unspecified
43.8
172.2
103
25
E000001, ,
ATC
4.2
166.6
623
2048
D02AE01
ATC
carbamide; topical
6.5
158.3
289
520
L40.8
ICD-10 Finland
Other psoriasis
79.2
155.2
83
11
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.8
149.6
663
2425
L40.5
ICD-10 Finland
Arthropathic psoriasis
325.6
148.1
148
5
L04AB04
ATC
adalimumab; parenteral
9.3
104.5
130
150
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.8
101.8
256
605
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.7
101.1
148
208
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
7.8
98.5
142
196
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.2
97.1
290
783
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.8
94.9
338
1034
E000002, ,
ATC
3.8
92.3
326
990
S91
ICPC
Psoriasis
47.7
87.0
51
11
L30.3
ICD-10 Finland
Infective dermatitis
6.2
86.4
156
273
L04AD01
ATC
ciclosporin; systemic
10.3
84.4
96
98
A07EC01
ATC
sulfasalazine; oral, rectal
4.0
79.4
248
687
M07.3
ICD-10 Finland
Other psoriatic arthropathies
212.3
79.0
81
*
E000006, ,
ATC
4.2
77.4
227
600
L01BA01
ATC
methotrexate; systemic
6.0
76.5
142
255
L04AA01
ATC
[U] ciclosporin
11.3
76.1
81
75
N07BA03
ATC
varenicline; oral
4.7
73.2
183
427
D07CC01
ATC
betamethasone and antibiotics; topical
3.2
72.0
350
1288
H02AB06
ATC
prednisolone; systemic
2.3
63.9
988
6279
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
12.5
63.6
63
52
L04AA13
ATC
[U] leflunomide
6.9
63.4
101
155
L40
ICD-10 Finland
Psoriasis
11.6
63.3
66
59
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.0
63.1
342
1331
E000004, ,
ATC
7.2
61.8
94
137
J01AA07
ATC
tetracycline; systemic
2.8
61.8
386
1619
J01AA04
ATC
lymecycline; systemic
2.9
61.5
341
1343
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
+∞
58.7
56
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
57.1
200
595
D09AB01
ATC
zinc bandage without supplements; topical
7.3
54.1
81
116
XQ802
NOMESCO Finland
Epicutan test
4.4
53.0
142
348
XQ848
NOMESCO Finland
Dermatological photography
5.3
52.3
109
217
L04AB01
ATC
etanercept; parenteral
7.8
50.8
71
94
68693
ICD-8 Finland
Other local infections of skin and subcutaneous tissue, Pustulosis palmo-plantaris
+∞
47.1
45
*
K05.31
ICD-10 Finland
Periodontitis pronounced
2.7
44.9
286
1197
6961D
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PUSTULOSIS PALMOPLANTARIS]
+∞
43.9
42
*
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
43.6
612
3588
D07AB08
ATC
desonide; topical
2.7
41.7
250
1012
Z72.0
ICD-10 Finland
Tobacco use
4.9
41.7
95
204
L04AC10
ATC
secukinumab; parenteral
56.0
41.6
49
9
L88
ICPC
Rheumatoid/seropositive arthritis
3.9
40.2
125
341
M13.9
ICD-10 Finland
Arthritis, unspecified
3.0
39.3
193
702
D02AX
ATC
Other emollients and protectives
4.8
38.4
89
194
E000007, ,
ATC
3.5
38.2
139
422
J01FF01
ATC
clindamycin; systemic
2.0
37.4
550
3245
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.9
37.3
193
722
S29
ICPC
Skin symptom/complaint other
2.1
37.0
431
2331
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
36.0
465
2613
L04AB06
ATC
golimumab; parenteral
9.1
34.3
42
47
J01DB01
ATC
cefalexin; oral
2.4
33.4
1488
12542
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
5.1
33.3
71
144
L43.0
ICD-10 Finland
Hypertrophic lichen planus
75.7
33.0
37
5
S21
ICPC
Skin texture symptom/complaint
2.2
32.6
328
1667
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
31.4
458
2667
377
Kela drug reimbursment
Apremilast and dimethyl fumarate (psoriasis)
+∞
31.3
30
*
L43.8
ICD-10 Finland
Other lichen planus
10.8
30.5
33
31
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
30.5
474
2818
T90
ICPC
Diabetes non-insulin dependent
2.0
30.4
456
2678
B35.3
ICD-10 Finland
Tinea pedis
3.4
30.3
116
363
N02AX02
ATC
tramadol; systemic, rectal
1.8
30.0
792
5548
D07AC14
ATC
methylprednisolone aceponate; topical
3.2
29.9
121
392
L04AC13
ATC
ixekizumab; parenteral
84.2
29.8
33
*
A10BA02
ATC
metformin; oral
1.9
29.3
508
3124
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.4
28.9
221
998
P17
ICPC
Tobacco abuse
6.0
28.8
51
87
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
28.1
830
5967
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.9
27.9
135
485
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.4
27.5
212
960
EBA00
NOMESCO Finland
Extraction of tooth
1.8
27.3
670
4557
L04AA32
ATC
apremilast; oral
+∞
27.2
26
*
L30.0
ICD-10 Finland
Nummular dermatitis
3.5
27.1
97
291
L08.0
ICD-10 Finland
Pyoderma
7.7
25.1
35
46
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
24.7
415
2506
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
6.5
24.4
40
63
S99
ICPC
Skin disease other
4.2
24.2
64
155
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.2
23.8
97
315
L40.1
ICD-10 Finland
Generalized pustular psoriasis
243.2
23.7
24
*
J01DA01
ATC
[U] cefalexin
1.7
23.3
1099
8784
P01AB01
ATC
metronidazole; oral, rectal
1.7
22.6
769
5633
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.7
22.5
72
200
R95
ICPC
Chron obstructive pulmonary disease
3.7
22.3
71
197
L30.1
ICD-10 Finland
Dyshidrosis [pompholyx]
9.1
22.1
27
30
WZA10
NOMESCO Finland
Extensive medical or dental certificate
5.4
21.9
43
81
L04AX01
ATC
azathioprine; systemic
3.1
21.7
94
317
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
5.1
21.7
46
93
D11AH04
ATC
alitretinoin; oral
31.6
21.5
28
9
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.9
21.2
285
1593
L04AC05
ATC
ustekinumab; parenteral
21.8
20.8
30
14
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
20.7
422
2682
A10BH01
ATC
sitagliptin; oral
2.2
20.5
176
831
SPAT1263
SPAT
Sampling
1.6
20.5
698
5080
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
20.4
729
5367
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
20.2
785
5893
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
20.1
409
2595
R03AC02
ATC
salbutamol; inhalant
1.6
19.9
991
7878
A46
ICD-10 Finland
Erysipelas
2.0
19.9
251
1371
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
5.9
19.7
35
60
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
19.6
165
773
D01BA02
ATC
terbinafine; oral
1.7
19.3
448
2946
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
19.2
191
955
D05AA
ATC
Tars
18.4
19.1
29
16
M54.5
ICD-10 Finland
Low back pain
1.6
19.0
676
4946
M073, L403,
ICD-10 Finland
+∞
18.8
18
*
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
18.8
18
*
SPAT1262
SPAT
Handing over of treatment supplies
1.9
18.7
284
1646
L43.9
ICD-10 Finland
Lichen planus, unspecified
6.0
18.7
33
56
L04AC16
ATC
guselkumab; systemic
192.0
18.6
19
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.4
18.4
131
570
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.1
17.8
75
249
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
17.2
355
2250
L17
ICPC
Foot/toe symptom/complaint
1.6
17.1
555
3951
ZY010
NOMESCO Finland
Hospital outpatient
2.6
17.0
104
421
R03BB04
ATC
tiotropium bromide; inhalant
2.1
17.0
176
893
R06AE07
ATC
cetirizine; oral
1.5
16.9
790
6103
A02BC02
ATC
pantoprazole; systemic
1.6
16.9
1203
10202
S97
ICPC
Chronic ulcer skin
2.4
16.8
115
491
D07AC03
ATC
desoximetasone; topical
4.3
16.7
43
102
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.1
16.5
173
882
D01AE15
ATC
terbinafine; topical
2.3
16.4
129
586
H02AB07
ATC
prednisone; oral
1.9
16.3
243
1397
K50.0
ICD-10 Finland
Crohn disease of small intestine
4.4
16.2
40
92
SPAT1283
SPAT
Restricted health certificate
1.8
16.0
282
1705
134
Kela drug reimbursment
General erythroderma
48.0
16.0
19
*
R02
ICPC
Shortness of breath/dyspnoea
1.9
16.0
242
1398
L04AC21
ATC
bimekizumab; systemic
+∞
15.6
15
*
L04AC18
ATC
risankizumab; parenteral
+∞
15.6
15
*
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
15.5
221
1252
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
15.5
630
4695
S76
ICPC
Skin infection other
2.4
15.4
107
460
M25.5
ICD-10 Finland
Pain in joint
1.5
15.3
626
4667
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
15.3
516
3686
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
15.3
638
4781
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
15.2
208
1164
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.7
15.0
84
326
L03
ICPC
Low back symptom/complaint
1.6
15.0
530
3826
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.2
14.9
128
603
L73.2
ICD-10 Finland
Hidradenitis suppurativa
4.4
14.8
37
86
M03BX02
ATC
tizanidine; oral
1.5
14.7
1112
9392
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
+∞
14.6
14
*
L40.2
ICD-10 Finland
Acrodermatitis continua
+∞
14.6
14
*
L40.4
ICD-10 Finland
Guttate psoriasis
36.4
14.4
18
5
A10BK03
ATC
empagliflozin; oral
1.9
14.3
188
1036
SPAT1301
SPAT
No procedures
1.6
14.2
482
3437
L30.8
ICD-10 Finland
Other specified dermatitis
2.9
14.2
66
232
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
14.1
130
630
M79.6
ICD-10 Finland
Pain in limb
1.5
14.1
779
6157
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.6
14.1
84
337
L20.0
ICD-10 Finland
Besnier prurigo
2.1
14.0
136
674
L04AK01
ATC
leflunomide; oral
6.1
13.9
24
40
P01BA02
ATC
hydroxychloroquine; oral
2.0
13.9
160
844
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.9
13.8
177
967
S87
ICPC
Dermatitis/atopic eczema
3.2
13.8
54
172
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.2
13.7
119
564
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.8
13.7
69
254
S10
ICPC
Boil/carbuncle
2.2
13.5
116
547
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
13.3
1240
10812
A10BJ06
ATC
semaglutide; parenteral
2.2
13.3
113
531
D07AA02
ATC
hydrocortisone; topical
1.8
13.3
230
1381
A10AE04
ATC
insulin glargine; parenteral
2.0
13.1
152
802
L30.4
ICD-10 Finland
Erythema intertrigo
3.9
13.1
38
99
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.8
13.1
218
1294
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.9
13.0
164
892
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.4
12.9
45
133
D05AX05
ATC
tazarotene; topical
50.4
12.8
15
*
SPAT1312
SPAT
General health counselling
1.5
12.7
489
3572
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.0
12.7
57
197
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
6.0
12.6
22
37
M07.0
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
12.5
12
*
L04AA11
ATC
[U] etanercept
11.7
12.3
22
19
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.0
12.3
132
678
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
3.2
12.3
49
158
L20
ICPC
Joint symptom/complaint NOS
2.5
12.2
78
323
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.6
12.2
71
281
N03AX16
ATC
[U] pregabalin
1.5
12.1
394
2770
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.7
12.1
64
242
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
12.0
393
2765
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
12.0
123
621
S18
ICPC
Laceration/cut
1.4
11.8
777
6274
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.2
11.8
97
449
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
11.8
1221
10719
K02.1
ICD-10 Finland
Caries of dentine
1.4
11.8
988
8338
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
4.8
11.7
26
55
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
11.6
582
4465
XQ800
NOMESCO Finland
Prick test
1.9
11.6
139
742
SPAT1260
SPAT
Consultation of another employee
1.6
11.6
275
1793
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
11.6
731
5851
R4180
NOMESCO Finland
Podiatric therapy
4.1
11.6
31
76
N05CD07
ATC
temazepam; oral
1.8
11.6
181
1053
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
11.6
186
1091
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
+∞
11.5
11
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
11.4
216
1327
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.6
11.4
67
267
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
3.3
11.4
42
129
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.1
11.4
47
155
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
11.3
393
2797
N02BE01
ATC
paracetamol; systemic, rectal
1.7
11.3
1536
14223
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
11.3
450
3298
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
11.2
937
7869
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
11.2
1126
9776
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
11.2
222
1383
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
11.2
473
3508
N05AH02
ATC
clozapine; systemic
3.5
11.1
38
111
S01
ICPC
Pain/tenderness of skin
2.3
11.1
87
396
N05BA04
ATC
oxazepam; oral
1.5
11.1
435
3177
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
11.0
329
2267
R05
ICPC
Cough
1.5
11.0
429
3129
F17.2
ICD-10 Finland
Mental and behavioural disorders due to use of tobacco, dependence syndrome
4.6
10.7
25
55
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
10.7
867
7219
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
5.6
10.7
20
36
D01AC02
ATC
miconazole; topical
2.0
10.7
120
627
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
10.5
328
2277
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.5
10.5
501
3792
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.7
10.5
54
201
A07EA06
ATC
budesonide; oral, local oral
2.4
10.5
69
290
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.3
10.5
78
347
L43.3
ICD-10 Finland
Subacute (active) lichen planus
32.7
10.3
13
*
K05.3
ICD-10 Finland
Chronic periodontitis
2.2
10.3
89
421
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
10.3
222
1411
SPAT1310
SPAT
Counselling related to known health issue
1.5
10.3
484
3652
N05AH04
ATC
quetiapine; oral
1.6
10.3
288
1951
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.2
10.3
39
122
M10.9
ICD-10 Finland
Gout, unspecified
2.1
10.2
97
476
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
10.2
608
4787
N05CF01
ATC
zopiclone; oral
1.4
10.2
518
3964
A01
ICPC
Pain general/multiple sites
1.7
10.2
181
1092
J01DA09
ATC
[U] cefadroxil
1.5
10.2
439
3257
K05.30
ICD-10 Finland
Periodontitis complex
1.6
10.2
263
1749
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
3.7
10.2
31
84
N05BA01
ATC
diazepam; systemic, rectal
1.7
10.1
217
1378
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
10.1
463
3475
Z3231
NOMESCO Finland
Registered nurse
1.5
10.1
416
3059
N06AX21
ATC
duloxetine; oral
1.6
10.1
221
1411
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
10.0
189
1159
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
3.9
10.0
29
76
A10BK01
ATC
dapagliflozin; oral
1.9
9.9
128
701
N06AB04
ATC
citalopram; systemic
1.5
9.9
346
2460
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
9.9
184
1125
R21
ICPC
Throat symptom/complaint
1.5
9.9
336
2375
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.3
9.9
37
115
R06AE09
ATC
levocetirizine; oral
1.6
9.8
248
1639
L85.1
ICD-10 Finland
Acquired keratosis [keratoderma] palmaris et plantaris
26.2
9.8
13
5
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.0
9.7
41
137
N03AX09
ATC
lamotrigine; oral
2.1
9.7
87
418
N05BB01
ATC
hydroxyzine; systemic
2.0
9.6
105
543
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
9.6
392
2873
N06AA09
ATC
amitriptyline; systemic
1.7
9.6
168
1011
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
9.5
150
874
L12
ICPC
Hand/finger symptom/complaint
1.5
9.5
293
2026
A10AB05
ATC
insulin aspart; parenteral
1.9
9.5
112
595
H01
ICPC
Ear pain/earache
1.7
9.5
199
1255
G47.3
ICD-10 Finland
Sleep apnoea
1.5
9.5
377
2748
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
2.9
9.5
43
150
K50.8
ICD-10 Finland
Other Crohn disease
3.4
9.5
33
98
J01FA06
ATC
roxithromycin; oral
1.4
9.5
661
5334
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
9.4
88
430
C10AA01
ATC
simvastatin; oral
1.4
9.4
584
4619
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.7
9.4
171
1039
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
9.4
9
*
N06AX11
ATC
mirtazapine; oral
1.4
9.4
568
4473
SFA10
NOMESCO Finland
One-surface restoration
1.4
9.4
917
7809
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
9.3
438
3296
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
2.5
9.3
58
239
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
9.3
212
1368
J01CF05
ATC
flucloxacillin; systemic
1.9
9.2
120
659
SFA30
NOMESCO Finland
Three-surface restoration
1.4
9.2
729
5996
M01AH01
ATC
celecoxib; oral
1.5
9.2
297
2074
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.4
9.2
63
271
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.3
9.2
71
322
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
4.3
9.1
23
54
J01AA02
ATC
doxycycline; systemic
1.4
9.1
1326
12031
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.7
9.1
47
176
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
9.1
295
2062
R60.0
ICD-10 Finland
Localized oedema
1.6
9.1
198
1262
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
9.1
106
562
R50.9
ICD-10 Finland
Fever, unspecified
1.6
9.0
235
1564
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
9.0
203
1305
M01AB05
ATC
diclofenac; systemic, rectal
1.4
9.0
1116
9842
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
4.2
8.9
23
55
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
8.9
121
674
SDA03
NOMESCO Finland
Periodontal treatment
1.4
8.9
693
5677
R52.9
ICD-10 Finland
Pain, unspecified
1.7
8.9
176
1095
S22.3
ICD-10 Finland
Fracture of rib
1.8
8.8
121
676
Z01.2
ICD-10 Finland
Dental examination
1.4
8.8
776
6475
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.3
8.8
66
295
A02BC01
ATC
omeprazole; systemic
1.4
8.8
415
3121
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
2.6
8.8
51
203
L03.9
ICD-10 Finland
Cellulitis, unspecified
2.9
8.7
39
135
D06AX01
ATC
fusidic acid; topical
1.7
8.7
145
860
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
50.2
8.7
10
*
L08
ICPC
Shoulder symptom/complaint
1.4
8.7
394
2942
EBA30
NOMESCO Finland
Extraction of root of tooth
2.0
8.7
98
514
SPAT1254
SPAT
Administration of medicine
1.6
8.6
195
1253
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
3.4
8.6
30
89
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
8.6
152
916
M01CB03
ATC
auranofin; oral
4.8
8.6
19
40
8511
FHL
Cervical dilation and drainage with suction
2.1
8.6
77
371
L28
ICPC
Limited function/disability (L)
1.5
8.6
284
1993
K50.1
ICD-10 Finland
Crohn disease of large intestine
3.7
8.5
26
71
C03CA01
ATC
furosemide; systemic
1.4
8.5
385
2874
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
3.1
8.4
35
116
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.7
8.4
43
160
L04AB05
ATC
certolizumab pegol; parenteral
7.4
8.4
19
26
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.1
8.4
75
360
WQ031, ,
NOMESCO Finland
90.5
8.4
9
*
N06AG02
ATC
moclobemide; oral
2.1
8.4
76
368
M45
ICD-10 Finland
Ankylosing spondylitis
2.8
8.4
40
144
N03AX12
ATC
[U] gabapentin; oral
1.5
8.3
265
1843
K04.7
ICD-10 Finland
Periapical abscess without sinus
1.9
8.3
100
537
K08.3
ICD-10 Finland
Retained dental root
1.8
8.2
121
691
S02
ICPC
Pruritus
2.3
8.2
62
278
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
8.2
440
3378
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.3
8.2
61
272
GD1AD
NOMESCO Finland
Thorax CT examination
1.9
8.2
102
553
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
8.2
573
4599
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
3.9
8.2
23
59
H29
ICPC
Ear symptom/complaint other
1.6
8.2
196
1279
-1, ,
NOMESCO Finland
1.4
8.1
513
4048
J01MA12
ATC
levofloxacin; systemic
1.5
8.1
275
1939
OAB50, ,
SPAT
1.7
8.1
133
786
D11
ICPC
Diarrhoea
1.6
8.1
192
1250
C07AB07
ATC
bisoprolol; oral
1.3
8.0
728
6075
EBA00, ,
SPAT
2.5
8.0
50
206
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
8.0
167
1052
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
3.9
8.0
23
60
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
8.0
177
1133
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.8
8.0
128
751
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
3.0
7.9
34
115
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
7.9
151
929
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.9
822
6998
D82
ICPC
Teeth/gum disease
1.4
7.8
607
4945
A07EC02
ATC
mesalazine; oral, rectal
2.0
7.8
85
441
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.8
757
6374
D07CB01
ATC
triamcinolone and antibiotics; topical
2.8
7.8
37
133
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
7.8
305
2212
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.9
7.7
96
520
TNG10
NOMESCO Finland
Puncture of knee
3.5
7.7
26
76
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.8
7.6
111
632
H02AB04
ATC
methylprednisolone; systemic
1.5
7.6
229
1574
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.6
612
5009
A03
ICPC
Fever
1.5
7.6
264
1870
NG1DA
NOMESCO Finland
X-ray of knees
2.8
7.5
36
130
A10BJ02
ATC
liraglutide; parenteral
2.3
7.5
57
257
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
7.5
153
959
SDA05
NOMESCO Finland
Very demanding periodontal treatment
1.7
7.3
119
701
299, ,
Kela drug reimbursment
+∞
7.3
7
*
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
3.9
7.3
21
55
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
7.2
136
834
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
7.2
614
5057
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
7.2
1538
14525
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.4
7.2
49
211
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.2
573
4673
EKA10
NOMESCO Finland
iopsy of buccal mucosa
2.6
7.1
39
151
K50.9
ICD-10 Finland
Crohn disease, unspecified
3.0
7.1
31
106
WQ021, ,
NOMESCO Finland
20.1
7.1
10
5
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
3.3
7.1
26
80
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
7.1
196
1320
S17
ICPC
Abrasion/scratch/blister
2.7
7.1
36
134
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
7.1
179
1181
N05AA02
ATC
levomepromazine; systemic
2.1
7.1
66
323
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
7.1
109
632
NDL52
NOMESCO Finland
Tenosynovectomy of hand
4.1
7.1
19
47
M04AA01
ATC
allopurinol; systemic
1.6
7.1
156
997
WX290
NOMESCO Finland
Other blockage of nerve
1.3
7.0
771
6570
NH1AD
NOMESCO Finland
Ankle and foot CT
2.5
7.0
42
170
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.4
7.0
347
2621
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.2
7.0
59
278
N02AA05
ATC
oxycodone; systemic
1.5
7.0
258
1847
SPAT1153
SPAT
Removal of sutures
1.4
7.0
466
3696
Z2446
NOMESCO Finland
Social worker
1.8
7.0
98
553
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
6.9
277
2012
A02BC03
ATC
lansoprazole; oral
1.4
6.9
454
3590
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.9
6.9
78
410
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
6.9
169
1108
N05AX12
ATC
aripiprazole; systemic
2.1
6.9
62
300
L84
ICD-10 Finland
Corns and callosities
2.1
6.9
59
280
A28
ICPC
Limited function/disability NOS
1.5
6.8
240
1700
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
6.8
152
974
L60.0
ICD-10 Finland
Ingrowing nail
1.9
6.8
81
434
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
6.8
445
3518
J45.1
ICD-10 Finland
Nonallergic asthma
1.7
6.8
111
656
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
6.8
94
529
C10AC01
ATC
colestyramine; oral
2.3
6.8
49
217
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
3.1
6.7
27
88
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
6.7
118
711
SPAT1281
SPAT
Other administrative function
1.7
6.7
110
650
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
3.4
6.7
23
68
N05AH03
ATC
olanzapine; systemic
1.8
6.7
102
590
WQ020, ,
NOMESCO Finland
22.6
6.7
9
*
N05AB03
ATC
perphenazine; systemic, rectal
2.1
6.6
59
284
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
2.3
6.6
50
225
R29
ICPC
Respiratory symptom/complaint other
1.7
6.6
113
675
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.5
6.6
40
163
L02.8
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of other sites
2.7
6.6
33
122
S04
ICPC
Lump/swelling localized
1.6
6.6
175
1168
D07XB01
ATC
flumetasone; topical
5.9
6.6
17
29
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
6.6
197
1350
UJF92
NOMESCO Finland
Capsular endoscopy
2.6
6.6
36
140
SPAT1229
SPAT
Assessment of need for aid
1.8
6.5
101
587
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
6.5
194
1328
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.8
6.5
94
535
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
1.8
6.5
88
491
SPAT1202
SPAT
Intra-articular injection
2.3
6.5
46
202
J02AC02
ATC
itraconazole; systemic
1.4
6.4
285
2109
L02
ICPC
Back symptom/complaint
1.6
6.4
169
1126
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.3
6.4
47
209
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.4
965
8537
L04
ICPC
Chest symptom/complaint
1.7
6.4
107
636
L88
ICD-10 Finland
Pyoderma gangrenosum
14.4
6.4
10
7
L16
ICPC
Ankle symptom/complaint
1.5
6.4
193
1326
EB1VA, ,
NOMESCO Finland
1.4
6.4
301
2252
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
6.4
213
1494
L14
ICPC
Leg/thigh symptom/complaint
1.6
6.4
132
831
S22
ICPC
Nail symptom/complaint
1.7
6.4
110
660
N05AX08
ATC
risperidone; systemic
1.7
6.4
114
691
M01AH05
ATC
etoricoxib; oral
1.3
6.3
1065
9553
SPAT1104
SPAT
Monitoring of emergency patient
1.8
6.3
87
488
S06
ICPC
Rash localized
1.8
6.3
86
481
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
3.1
6.3
25
81
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.3
6.3
435
3459
SPAT1211
SPAT
Application of soft bandage
1.7
6.3
121
747
J04BA02
ATC
dapsone; oral
6.0
6.3
16
27
H70
ICPC
Otitis externa
2.5
6.3
37
149
ZYC01
NOMESCO Finland
Remote contact by phone
1.7
6.3
101
594
A02BC05
ATC
esomeprazole; systemic
1.3
6.3
656
5530
WZC00, ,
SPAT
1.5
6.3
228
1626
J01FA09
ATC
clarithromycin; systemic
1.3
6.3
500
4062
SPD00
NOMESCO Finland
Mucosa borne complete denture
3.7
6.2
19
52
SPAT1240
SPAT
Therapeutic discussion
1.6
6.2
153
1005
UJF32
NOMESCO Finland
Coloscopy
1.4
6.2
389
3050
R06.0
ICD-10 Finland
Dyspnoea
1.3
6.2
406
3205
SPC35
NOMESCO Finland
Production and attachment of fibre-reinforced dental bridge
2.9
6.2
27
93
SPA02
NOMESCO Finland
Preparation for dental prosthetics
2.0
6.2
59
293
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.1
410
3244
SPAT1216
SPAT
Assessment of functional ability
1.5
6.1
205
1438
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
6.1
288
2153
R60.9
ICD-10 Finland
Oedema, unspecified
1.8
6.1
87
494
A10BB12
ATC
glimepiride; oral
1.8
6.1
81
450
H02BX01
ATC
methylprednisolone, combinations; systemic
1.9
6.1
71
378
256, ,
Kela drug reimbursment
12.6
6.1
10
8
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.7
6.0
103
616
N05BE01
ATC
buspirone; oral
2.2
6.0
49
228
L86
ICPC
Back syndrome with radiating pain
1.7
6.0
101
601

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1217
7961
2.79
82.31
10.8
6.1
0.05
0.04
e9/l
14.93
1094
6867
1214
7939
2.78
82.02
10.8
6.1
0.62
0.56
e9/l
18.84
1094
6854
1238
8224
2.79
80.19
11.0
6.3
0.21
0.19
e9/l
8.50
1133
7202
1225
8122
2.75
79.15
10.9
6.1
2.14
1.96
e9/l
4.58
1123
7188
897
5171
2.53
77.06
9.6
6.0
—
—
—
0
0
1129
7295
2.58
75.11
10.9
6.3
8.49
8.71
%
2.06
1084
6853
458
1923
2.88
74.68
1.5
1.4
—
—
—
0
0
1125
7283
2.56
74.11
10.8
6.2
2.87
2.84
%
0.24
1081
6834
1124
7283
2.56
73.74
11.0
6.3
0.74
0.70
%
2.08
1080
6825
1136
7485
2.51
70.43
10.8
6.2
28.33
28.45
%
0.16
1099
7114
1118
7359
2.47
68.72
10.7
6.1
57.50
56.65
%
1.82
1091
7042
1274
8984
2.60
66.11
14.2
9.7
4.46
3.96
e9/l
14.51
1147
7863
46
34
13.87
49.47
1.4
1.4
9.41
9.45
ug/l
0.01
46
34
182
638
3.07
39.53
1.2
1.2
—
—
—
0
0
427
2350
2.09
34.77
1.4
1.3
531.69
535.70
titre
0.01
89
502
961
6945
1.87
34.48
16.2
11.0
0.00
0.00
e9/l
0.93
794
5691
284
1341
2.34
33.79
4.9
4.4
0.39
0.74
%
3.09
93
396
284
1364
2.30
32.38
5.8
4.8
0.00
0.31
%
0.72
88
335
281
1348
2.30
32.11
5.4
4.6
0.06
0.13
%
1.67
86
359
289
1412
2.26
31.58
5.3
4.5
0.49
1.11
%
6.43
95
424
1430
12017
2.11
29.87
11.0
8.3
79.48
78.34
u/l
0.40
1365
11445
330
1772
2.07
28.08
1.7
1.7
—
—
—
0
0
1385
11664
1.95
26.44
7.7
4.3
15.34
11.84
mm/h
13.35
1314
10973
118
408
3.03
26.08
1.7
1.3
—
—
—
0
0
163
685
2.52
24.78
1.6
1.9
7.32
8.09
iu/ml
0.13
29
172
35
49
7.27
23.78
1.8
2.1
6.99
9.55
mg/l
1.80
30
41
1047
8245
1.69
23.66
4.7
3.8
0.00
0.00
estimate
0.80
232
1663
1061
8412
1.68
23.10
4.8
3.8
4.48
0.20
estimate
0.47
223
1613
1053
8335
1.68
23.04
4.7
3.8
5.95
5.49
estimate
0.03
238
1712
54
121
4.57
22.51
1.7
1.4
27.73
33.91
%
0.44
32
73
1254
10445
1.73
22.21
5.8
4.5
—
2.94
—
0
16
473
3055
1.76
22.17
1.4
1.3
14.03
11.47
u/ml
0.32
176
1217
578
3957
1.69
21.87
4.5
4.3
—
—
—
0
0
108
393
2.86
21.77
2.0
1.6
11855.21
10275.23
e6/l
0.23
81
274
535
3600
1.70
21.52
7.4
4.6
—
—
—
0
0
62
161
3.96
21.35
1.7
1.5
54.26
60.36
%
0.46
39
102
139
582
2.51
21.25
1.1
1.1
—
—
—
0
0
903
6966
1.62
21.05
5.2
5.0
35.47
36.05
g/l
2.64
847
6574
357
2153
1.83
20.95
2.2
2.0
—
—
—
0
0
725
5311
1.63
20.80
4.0
3.3
7.21
7.36
mmol/l
0.39
604
4552
576
3995
1.66
20.45
3.1
2.6
337.25
330.14
umol/l
0.92
499
3567
340
2053
1.82
19.76
4.2
3.1
4.46
4.72
e9/l
0.34
304
1817
977
7815
1.58
18.54
7.1
7.2
1.22
1.22
mmol/l
0.64
850
6814
748
5644
1.57
18.21
4.7
3.8
69.43
97.05
e6/l
0.80
522
3896
484
3303
1.65
17.85
1.5
1.3
38.33
31.18
iu/ml
0.41
139
1037
684
5107
1.56
17.14
4.9
4.0
8.01
8.05
mg/mmol
0.01
427
3072
87
327
2.75
16.52
3.8
3.3
55.43
58.30
%
1.27
87
327
656
4882
1.55
16.52
3.8
3.2
33.99
92.15
e6/l
1.87
505
3677
669
5018
1.54
16.16
4.0
3.4
52.24
43.92
mg/l
0.49
428
3064
67
224
3.07
15.72
1.9
3.6
2.04
1.74
%
0.15
58
207
206
1143
1.91
15.41
1.3
1.5
—
—
—
0
0
571
4188
1.54
15.01
3.7
3.1
0.50
0.43
e6/l
0.20
425
3013
873
7001
1.50
15.01
6.4
6.5
1.22
1.21
mmol/l
0.39
816
6489
999
8303
1.48
13.93
6.3
6.8
9.30
10.92
umol/l
7.39
944
7939
323
2104
1.66
13.87
3.3
2.3
178.02
115.10
ug/g
1.63
259
1680
913
7466
1.47
13.75
3.0
2.5
75.16
77.94
nmol/l
2.45
838
6810
273
1713
1.71
13.48
1.4
1.6
—
—
—
0
0
467
3353
1.54
13.22
2.9
2.6
6.19
6.61
e6/l
0.22
426
3041
824
6641
1.46
13.15
4.3
3.3
6.21
6.21
ph
0.00
416
3775
841
6812
1.46
13.03
11.1
12.9
1.21
1.20
inr
0.08
693
5635
1061
8986
1.47
13.00
5.5
5.0
6.82
6.60
mmol/l
2.73
1019
8535
597
4535
1.48
12.82
5.0
3.9
0.00
0.01
estimate
1.74
217
1587
402
2812
1.56
12.73
2.9
2.8
526.03
519.17
mosm/kgh2o
0.22
350
2455
1156
9982
1.48
12.63
5.2
4.5
162.67
1747.29
e6/l
3.39
15
146
646
4997
1.47
12.60
3.2
2.6
55.61
61.01
u/l
1.06
586
4644
633
4902
1.46
12.17
8.3
6.1
—
—
—
0
0
622
4814
1.46
11.94
2.4
2.2
204.03
207.99
u/l
0.04
573
4583
612
4741
1.45
11.61
4.4
4.2
7.40
7.40
ph
0.57
434
3399
510
3837
1.47
11.19
1.3
1.3
1.79
1.44
u/ml
0.14
125
1064
21
38
5.58
11.18
2.4
2.8
—
41.11
—
0
9
1605
15072
1.93
11.07
22.6
15.0
21.53
22.31
mg/l
0.48
1442
12309
242
1547
1.66
11.03
2.3
2.1
380.36
379.60
nmol/l
0.01
222
1443
828
6819
1.41
11.01
2.3
2.1
93.95
98.26
pmol/l
1.97
460
3483
23
46
5.05
11.00
2.8
3.4
8.63
8.56
mg/l
0.01
16
41
367
2611
1.52
10.53
3.8
3.6
0.79
0.82
mmol/l
6.04
341
2479
204
1262
1.70
10.51
2.2
2.9
10.85
10.55
g/l
0.47
185
1166
838
6955
1.40
10.45
2.4
1.9
1.64
1.37
mmol/l
10.56
696
5926
446
3307
1.47
10.42
1.5
1.5
2.79
2.37
g/l
4.02
254
2069
316
2191
1.54
10.19
1.5
1.6
—
—
—
0
0
507
3901
1.42
9.59
2.4
2.3
2.93
2.82
mg/l
0.41
443
3373
356
2566
1.49
9.49
2.2
2.5
12.64
13.43
umol/l
1.19
335
2391
363
2627
1.48
9.48
3.4
2.8
1.25
1.02
e6/l
0.64
187
1346
26
66
3.98
9.33
1.2
1.1
391.70
222.20
iu/ml
0.35
26
66
325
2317
1.50
9.11
1.8
1.7
1013.49
1198.58
nmol/l
3.89
251
1771
42
148
2.88
9.10
1.5
1.3
40062.73
156389.79
e6/l
0.92
26
101
199
1270
1.64
9.08
2.4
3.1
67.30
66.99
g/l
0.24
186
1178
73
341
2.19
8.78
1.2
1.2
—
—
—
0
0
331
2386
1.48
8.76
3.5
2.9
5.45
2.82
e6/l
1.34
151
1109
195
1250
1.63
8.73
2.4
2.4
0.38
0.54
e6/l
0.59
180
1190
591
4736
1.38
8.62
3.3
3.1
—
—
—
0
0
346
2534
1.46
8.41
1.5
1.8
—
—
—
0
0
286
2022
1.50
8.30
4.8
5.9
1.03
1.03
mmol/l
0.00
264
1871
118
671
1.81
8.15
1.3
1.2
0.22
1.06
u/ml
—
10
46
1538
14459
1.58
8.10
7.9
6.1
40.95
38.97
mmol/mol
13.05
1437
13627
750
6295
1.34
7.92
4.8
3.6
2.59
0.13
estimate
0.47
194
1347
182
1180
1.61
7.78
1.3
1.3
488.44
201.73
u/ml
1.72
177
1088
92
492
1.92
7.71
3.2
2.5
25.34
24.82
mmol/l
0.64
92
486
37
134
2.80
7.67
2.0
3.8
55.97
56.37
%
0.04
32
121
663
5484
1.34
7.65
3.7
3.3
32.13
31.33
u/l
0.12
616
5202
197
1311
1.57
7.54
1.2
1.2
—
—
—
0
0
126
751
1.73
7.43
2.0
2.2
0.10
1.05
estimate
0.43
48
239
319
2358
1.43
7.30
2.2
2.5
2.45
2.36
g/l
2.04
296
2185
560
4553
1.34
7.15
3.5
2.9
0.13
0.02
—
8
84
219
1512
1.51
7.08
2.1
2.2
0.23
0.21
g/l
1.32
203
1430
217
1496
1.52
7.07
2.0
2.1
0.02
0.02
estimate
0.07
50
314
532
4311
1.34
6.90
3.1
3.0
1414.05
983.87
ng/l
1.26
441
3681
156
1004
1.61
6.88
1.5
1.8
1.15
1.39
g/l
1.49
141
929
553
4515
1.33
6.79
3.9
3.2
0.26
0.23
estimate
0.04
192
1319
160
1040
1.59
6.77
2.2
2.6
—
—
—
0
0
1178
10672
1.33
6.76
4.1
3.3
51.71
45.88
u/l
1.01
1093
10084
86
476
1.85
6.53
1.6
1.4
259.67
296.33
ug/g
0.76
48
273
88
492
1.83
6.47
1.6
1.8
0.25
0.24
g/l
0.51
83
473
1341
12413
1.36
6.45
5.4
4.7
14.83
14.71
pmol/l
1.06
1246
11534
10
7
14.36
6.40
2.3
2.6
2.37
3.46
mg/l
—
10
7
291
2166
1.41
6.35
2.2
2.6
19.76
22.83
%
3.78
269
2022
1613
15472
1.65
6.22
22.4
17.3
139.66
139.78
mmol/l
1.13
1584
15212
666
5633
1.30
6.19
3.0
3.6
2.36
2.36
mmol/l
0.58
602
5166
399
3146
1.35
6.10
1.8
1.7
81515576.35
35924968.40
pmol/l
0.42
330
2650
1517
14373
1.46
6.06
6.6
5.7
1.73
1.89
mu/l
7.36
1420
13433
88
505
1.78
5.96
1.3
1.3
10.11
10.02
u/ml
—
7
82
116
1805
0.62
5.95
1.9
2.0
3.65
3.42
ratio
1.33
91
1422
235
1707
1.44
5.86
6.9
8.7
11.51
12.62
kpa
3.03
227
1653
235
1707
1.44
5.86
6.9
8.7
5.27
5.11
kpa
1.65
228
1653
51
245
2.11
5.82
1.2
1.1
12466.04
115.46
iu/ml
—
10
50
1653
15990
1.80
5.77
19.7
12.0
26.11
25.63
u/l
0.61
1628
15608
92
542
1.74
5.71
2.3
2.5
10.34
10.28
g/l
0.04
83
497
1591
15250
1.55
5.68
6.4
5.2
4.64
4.77
mmol/l
6.33
1507
14360
525
4342
1.30
5.68
1.8
1.7
19.68
20.86
nmol/l
0.96
440
3686
232
1691
1.43
5.68
6.9
8.7
1.21
1.05
mmol/l
0.22
199
1404
1612
15501
1.60
5.63
22.6
17.5
3.98
3.96
mmol/l
3.69
1584
15210
44
203
2.20
5.56
1.4
1.2
—
—
—
0
0
88
516
1.74
5.56
2.4
2.2
490.69
363.53
ug/l
0.22
83
489
1550
14789
1.47
5.53
6.0
5.1
6.21
5.87
mmol/l
16.35
1430
13720
179
1251
1.48
5.46
3.4
3.6
74.98
81.63
ng/l
0.75
152
1094
1659
16086
1.81
5.43
28.5
19.3
72.13
73.37
umol/l
1.06
1650
15930
160
1095
1.51
5.40
4.3
3.7
4.57
4.52
pmol/l
0.28
151
979
62
329
1.92
5.40
2.1
2.4
77.44
100.01
ug/min
0.24
30
201
232
1709
1.41
5.35
6.9
8.7
7.40
7.42
ph
1.66
125
933
484
3987
1.30
5.34
4.2
3.9
95.00
93.21
%
0.89
462
3894
221
1616
1.42
5.31
2.1
2.9
1.82
1.84
%
0.11
204
1455
65
354
1.87
5.25
2.6
1.4
—
—
—
0
0
200
1441
1.44
5.21
3.8
3.4
7.37
7.38
ph
1.55
112
778
172
1205
1.47
5.19
4.7
3.8
—
—
—
0
0
81
1325
0.59
5.10
1.7
1.8
3.58
3.52
mmol/l
0.20
57
946
1580
15173
1.49
5.02
5.8
5.1
1.43
1.52
mmol/l
13.57
1475
14213
198
1435
1.43
5.00
3.8
3.4
5.97
5.82
kpa
1.05
192
1394
46
226
2.06
4.99
6.5
6.3
389.83
368.63
umol/l
0.41
36
207
192
1387
1.43
4.93
3.7
3.4
1.91
1.82
mmol/l
0.10
170
1209
21
72
2.94
4.88
2.0
1.5
—
—
—
0
0
1360
12767
1.31
4.87
28.1
18.5
13.88
13.58
%
13.18
1341
12593
1601
15428
1.52
4.87
6.8
5.9
2.70
2.80
mmol/l
4.29
1499
14479
139
952
1.50
4.70
3.3
3.3
5.31
5.14
kpa
1.29
133
924
39
185
2.13
4.65
3.7
1.6
—
—
—
0
0
172
1237
1.43
4.54
2.0
2.9
71.35
72.68
e9/l
0.21
116
901
438
3631
1.28
4.49
1.7
1.8
1.06
1.15
mg/l
0.37
351
2792
30
131
2.31
4.37
2.3
4.2
—
—
—
0
0
72
431
1.70
4.29
2.6
1.4
—
—
—
0
0
56
960
0.57
4.24
1.6
1.8
—
—
—
0
0
23
90
2.58
4.22
1.2
1.5
1.20
1.24
nmol/l
0.06
15
64
15
46
3.28
4.19
1.5
1.5
6.47
7.74
mmol/l
0.64
15
46
102
676
1.54
4.05
4.2
4.2
36.91
36.91
°c
0.09
102
671
122
841
1.48
4.03
1.3
1.2
—
—
—
0
0
87
557
1.59
4.01
2.2
2.0
1.63
1.88
ug/l
0.13
78
503
37
184
2.03
3.95
1.5
1.5
21.75
23.58
ng/l
0.23
37
184
51
284
1.82
3.92
4.4
2.5
15.98
16.33
%
0.42
51
279
654
5744
1.22
3.91
4.1
3.5
37.12
49.00
ng/l
0.40
437
3854
435
3657
1.25
3.91
5.1
3.9
1.02
1.02
kg/l
0.04
304
2426
357
2933
1.27
3.89
4.5
3.6
216.78
382.77
ng/l
0.81
252
2155
134
949
1.45
3.87
7.1
8.5
25.19
25.07
mmol/l
0.14
134
944
1510
14490
1.34
3.86
5.3
4.3
1.52
1.29
mmol/l
18.86
1400
13451
162
1188
1.40
3.85
3.2
2.8
4.59
4.50
kpa
0.25
156
1149
245
1923
1.32
3.78
1.5
1.3
—
—
—
0
0
79
507
1.58
3.64
2.2
2.1
4.03
15.66
iu/l
0.51
32
204
130
928
1.43
3.61
3.4
3.3
7.41
7.42
ph
0.64
108
779
40
212
1.91
3.60
2.3
1.8
1.78
1.69
mmol/l
0.26
40
206
74
473
1.59
3.48
2.6
1.4
—
—
—
0
0
69
434
1.61
3.46
2.3
2.2
12.47
11.96
mg/l
0.18
61
406
107
1511
0.69
3.46
1.2
1.4
—
—
—
0
0
562
6376
0.82
3.46
3.8
3.1
—
—
—
0
0
54
320
1.71
3.40
3.6
1.8
—
—
—
0
0
156
1163
1.38
3.39
2.3
2.4
19.68
21.19
au/ml
—
10
117
163
1224
1.37
3.38
3.8
3.9
1.23
1.23
mmol/l
0.55
140
1058
73
469
1.58
3.37
2.6
1.4
—
—
—
0
0
73
469
1.58
3.37
2.6
1.4
—
—
—
0
0
52
310
1.70
3.22
1.3
2.0
0.93
0.88
nmol/l
0.15
46
265
40
221
1.83
3.20
1.2
1.4
0.15
0.26
nmol/l
0.66
25
166
46
266
1.75
3.18
1.3
1.6
0.68
0.76
g/l
0.25
36
214
72
469
1.56
3.15
2.6
1.4
—
—
—
0
0
91
624
1.48
3.14
1.3
1.9
1.83
1.59
g/l
1.29
77
551
11
30
3.68
3.08
1.0
1.3
—
—
—
0
0
69
449
1.56
3.04
3.3
3.6
1.75
3.14
ratio
0.88
40
249
38
211
1.82
3.01
1.2
1.4
—
—
nmol/l
—
0
0
36
197
1.85
2.99
2.1
2.5
—
—
—
0
0
19
82
2.33
2.91
1.0
1.3
12.36
10.86
u/l
0.26
14
73
569
5046
1.19
2.88
2.5
2.3
—
—
—
0
0
25
123
2.05
2.82
1.1
1.2
2.00
2.02
mmol/l
0.05
25
116
93
657
1.44
2.79
1.4
1.6
0.40
0.34
mg/l
0.41
38
291
795
7272
1.17
2.75
2.9
2.7
—
—
estimate
—
0
0
193
1536
1.29
2.71
3.3
2.4
38.56
41.60
u/l
0.16
157
1297
73
495
1.50
2.70
3.3
3.9
50.79
66.48
mg/l
0.37
64
430
73
495
1.50
2.70
3.3
3.9
26.64
44.43
mg/l
1.51
63
431
38
633
0.59
2.68
1.1
1.2
0.91
0.89
g/l
0.14
38
633
14
55
2.56
2.61
1.2
1.6
58.46
573.25
nmol/24h
0.51
14
55
25
127
1.98
2.61
3.4
2.9
38.07
28.50
mg/l
0.20
17
90
165
1296
1.30
2.57
6.3
7.6
9.81
8.94
mmol/l
0.76
158
1249
163
1280
1.30
2.55
7.9
9.2
—
—
—
0
0
37
611
0.60
2.54
1.1
1.2
1.57
1.58
g/l
0.09
37
611
160
1255
1.30
2.52
1.3
1.2
126.60
153.93
u/ml
0.38
53
499
48
301
1.61
2.52
4.3
2.6
90.18
89.99
%
0.08
48
292
48
303
1.60
2.46
4.9
3.5
—
—
—
0
0
1671
16438
1.52
2.45
34.7
22.9
275.20
257.00
e9/l
23.28
1639
16154
1671
16441
1.51
2.41
34.6
22.8
91.89
91.07
fl
10.94
1657
16296
29
160
1.83
2.40
1.1
1.5
0.40
0.37
g/l
0.22
22
120
29
160
1.83
2.40
1.1
1.5
3.85
2.97
g/l
1.02
22
120
29
160
1.83
2.40
1.1
1.5
6.63
6.78
g/l
0.11
22
121
44
274
1.62
2.39
4.9
3.9
2.31
2.65
mmol/l
0.47
35
192
5
8
6.26
2.37
1.0
1.0
—
—
—
0
0
1671
16444
1.51
2.37
34.6
22.9
4.44
4.48
e12/l
2.99
1635
16107
1671
16444
1.51
2.37
34.5
22.8
30.40
30.28
pg
1.91
1657
16298
1671
16444
1.51
2.37
35.1
23.4
40.36
40.29
%
0.24
1657
16291
225
1856
1.24
2.36
2.9
2.8
6.43
7.28
umol/l
0.43
190
1636
13
52
2.51
2.36
1.2
1.1
—
—
—
0
0
23
118
1.96
2.35
1.1
1.1
—
—
—
0
0
1671
16446
1.50
2.34
34.7
23.0
7.54
6.62
e9/l
41.26
1636
16106
43
268
1.62
2.33
1.3
1.3
—
18.43
u/ml
—
0
7
1671
16448
1.50
2.32
35.0
23.0
134.03
134.74
g/l
1.32
1657
16304
50
324
1.56
2.31
2.1
2.2
4.83
5.23
mmol/24h
0.42
45
284
33
192
1.73
2.31
1.7
2.5
0.84
0.94
%
0.53
22
129
368
3197
1.19
2.30
2.9
2.9
2.47
2.45
mmol/l
3.94
325
2885
78
556
1.42
2.28
1.3
1.2
—
—
—
0
0
19
92
2.08
2.27
2.2
2.8
15.71
16.57
%
0.67
19
92
65
448
1.47
2.27
3.0
3.2
1.62
1.50
mg/l
0.50
60
412
117
894
1.33
2.24
2.7
2.9
131.40
129.49
g/l
0.40
112
866
51
335
1.54
2.23
1.4
1.8
—
—
—
0
0
28
158
1.78
2.18
1.1
1.5
—
—
—
0
0
168
1355
1.27
2.16
7.1
8.0
1.27
1.30
mmol/l
0.13
163
1331
42
266
1.59
2.16
1.0
1.1
—
—
—
0
0
39
245
1.61
2.08
1.2
1.4
30.42
30.70
u/l
0.02
31
205
14
62
2.27
2.08
2.2
3.4
339.00
150.46
umol/l
—
9
37
20
103
1.95
2.05
3.8
1.5
7.10
6.73
mmol/l
—
10
66
6
15
4.01
2.04
15.7
4.3
0.27
0.17
%
—
6
15
25
140
1.80
2.01
1.0
1.1
117.76
111.96
pmol/l
0.22
25
140
10
38
2.64
2.00
1.7
1.2
—
—
—
0
0
177
1454
1.24
1.96
3.9
4.0
7.38
7.35
ph
2.27
137
1049
27
157
1.73
1.93
1.0
1.1
—
—
—
0
0
52
356
1.47
1.92
3.6
2.1
129.89
130.21
g/l
0.03
44
283
17
85
2.01
1.90
1.9
1.8
2.55
4.14
nmol/l
0.29
17
70
52
357
1.47
1.89
4.3
2.6
8.35
8.12
kpa
0.47
52
351
64
458
1.41
1.88
1.8
2.1
118.61
3984.79
u/l
2.97
27
189
84
630
1.35
1.87
1.5
1.6
11.01
14.34
u/ml
0.28
15
145
810
7561
1.13
1.86
3.3
3.0
119.65
112.64
ug/l
0.15
750
7109
98
755
1.32
1.82
3.0
2.5
0.61
0.63
%
0.24
98
749
99
771
1.30
1.72
2.3
2.3
—
—
—
0
0
153
1258
1.24
1.71
3.4
2.4
6.04
6.06
ph
0.10
108
831
32
491
0.65
1.69
1.6
1.6
897.59
1010.25
mu/l
0.27
25
407
267
2319
1.18
1.68
1.3
1.2
—
—
—
0
0
6
19
3.17
1.66
1.0
3.8
—
19.27
—
0
7
7
25
2.81
1.65
1.3
1.1
0.08
0.02
u/ml
—
7
25
5
14
3.58
1.61
1.0
1.0
—
—
—
0
0
69
517
1.35
1.58
2.5
3.5
225.39
262.95
mg/l
0.27
31
222
19
107
1.78
1.55
1.8
1.5
72.74
77.16
umol/l
0.34
19
107
21
122
1.73
1.54
1.4
1.7
—
—
—
0
0
0
42
0.00
1.52
0.0
1.2
—
—
—
0
0
12
232
0.51
1.52
1.7
1.6
—
—
—
0
0
0
43
0.00
1.52
0.0
1.0
—
—
—
0
0
21
123
1.72
1.51
1.3
1.4
4760.00
133315.58
e6/l
—
7
60
6
21
2.86
1.50
1.8
1.4
—
—
—
0
0
11
51
2.16
1.50
1.1
1.3
27.82
27.84
s
0.01
11
51
12
58
2.08
1.49
1.4
1.9
35.97
51.23
ug/l
1.18
12
58
7
28
2.51
1.45
1.0
1.0
—
—
—
0
0
96
765
1.27
1.44
3.1
2.5
1.73
1.23
%
2.48
96
758
6
22
2.73
1.43
1.0
1.1
0.01
0.07
u/ml
—
6
22
19
110
1.74
1.43
1.5
2.4
800.00
612.20
ml
—
10
79
41
288
1.43
1.39
1.4
1.4
66.33
59.20
mmol/l
0.34
30
241
19
111
1.72
1.39
2.7
1.7
92.01
95.57
ng/l
0.07
19
111
12
224
0.53
1.38
1.7
1.5
—
—
—
0
0
419
3815
1.13
1.38
2.5
2.3
—
—
—
0
0
47
340
1.39
1.36
3.0
2.6
1.60
1.56
mmol/l
0.10
47
327
82
648
1.28
1.33
2.7
3.4
—
—
—
0
0
19
113
1.69
1.32
1.1
1.0
—
—
—
0
0
5
18
2.78
1.28
1.6
1.4
231.80
123.28
ug/l
—
5
18
10
48
2.09
1.27
1.2
1.2
6.28
7.41
pmol/l
—
5
17
21
130
1.62
1.27
1.1
1.1
—
—
—
0
0
28
186
1.51
1.26
1.4
1.4
275.00
278.19
mosm/kgh2o
0.21
16
148
28
186
1.51
1.26
2.1
2.5
0.89
1.05
g/24h
0.18
15
116
214
1874
1.16
1.25
4.9
4.9
31.16
32.53
%
1.15
161
1251
53
399
1.34
1.23
2.7
3.5
1.78
2.14
index
0.22
23
213
24
155
1.56
1.23
1.9
2.3
—
—
—
0
0
33
467
0.70
1.23
1.4
1.6
109.94
216.68
pmol/l
1.34
33
457
12
63
1.91
1.23
1.8
1.9
40.00
30.94
%
0.98
12
63
22
140
1.58
1.20
1.3
1.4
4879.60
2934.03
e6/l
—
10
88
162
1874
0.85
1.19
3.2
3.2
0.60
0.74
ug/l
2.88
111
1164
38
273
1.40
1.18
1.0
1.0
—
—
—
0
0
22
141
1.57
1.17
1.1
1.1
—
—
—
0
0
693
6542
1.10
1.15
2.1
2.1
—
—
—
0
0
11
197
0.56
1.14
1.4
1.7
—
—
—
0
0
28
191
1.47
1.14
1.1
1.8
—
1552.00
—
0
5
0
36
0.00
1.14
0.0
1.3
—
69.81
—
0
36
23
153
1.51
1.06
1.3
1.2
—
—
—
0
0
201
1778
1.15
1.05
1.6
1.6
—
—
—
0
0
15
90
1.67
1.04
1.0
1.2
—
—
—
0
0
7
34
2.06
1.03
1.1
1.1
—
—
—
0
0
19
122
1.56
1.02
1.3
1.4
—
—
—
0
0
19
122
1.56
1.02
1.4
1.4
—
—
—
0
0
34
247
1.38
1.02
1.7
1.2
—
—
—
0
0
14
84
1.67
0.98
1.4
1.2
—
—
—
0
0
0
29
0.00
0.97
0.0
3.3
—
—
—
0
0
89
741
1.21
0.97
3.6
3.0
1.02
1.02
ratio
0.08
82
671
1576
15546
1.16
0.97
18.0
13.3
—
—
—
0
0
10
54
1.86
0.96
9.5
3.3
—
—
—
0
0
0
31
0.00
0.96
0.0
3.4
—
—
—
0
0
13
77
1.69
0.95
2.3
2.9
737.85
892.56
u/ml
0.32
13
77
11
62
1.78
0.94
8.7
3.0
—
—
—
0
0
6
27
2.23
0.93
1.0
1.0
—
—
—
0
0
9
52
1.73
0.92
2.9
2.5
—
—
—
0
0
9
52
1.73
0.92
2.4
1.9
0.11
0.00
estimate
—
9
52
87
728
1.21
0.91
2.1
1.9
—
—
—
0
0
248
2251
1.12
0.89
1.9
2.2
30.48
29.27
s
1.98
241
2193
121
1046
1.17
0.89
3.1
3.1
153.19
165.15
ng/l
0.18
113
961
1255
12842
0.92
0.88
29.5
19.1
330.55
331.81
g/l
5.67
1247
12779
8
44
1.82
0.86
1.0
1.2
58.75
62.49
%
—
8
35
41
317
1.30
0.85
3.8
3.8
—
—
—
0
0
26
189
1.38
0.81
2.1
2.4
—
—
—
0
0
8
47
1.71
0.80
2.0
1.3
—
—
—
0
0
17
114
1.50
0.79
1.2
1.4
—
—
—
0
0
6
33
1.82
0.79
1.0
1.2
—
—
—
0
0
7
122
0.57
0.78
1.1
1.5
13.49
12.05
umol/l
—
7
113
33
252
1.32
0.77
1.2
1.2
—
—
—
0
0
26
348
0.74
0.76
3.3
4.0
15.69
30.79
u/ml
2.93
26
339
16
107
1.50
0.76
1.6
2.1
11.81
14.69
%
0.64
16
102
61
509
1.21
0.70
2.7
3.4
24.74
24.94
mmol/l
0.19
56
477
131
1166
1.13
0.68
1.3
1.3
—
—
—
0
0
60
503
1.20
0.67
2.5
1.7
250.19
311.06
mu/l
1.60
53
459
59
494
1.20
0.66
3.0
2.6
—
—
—
0
0
21
283
0.74
0.66
1.8
1.5
0.45
0.38
nmol/l
0.10
13
209
26
197
1.32
0.66
1.2
1.2
—
—
—
0
0
78
898
0.86
0.62
2.5
2.3
10.20
12.57
nmol/l
1.94
70
824
40
489
0.81
0.61
10.1
9.2
—
—
—
0
0
16
113
1.42
0.61
1.8
2.0
80.00
74.37
%
1.20
16
105
8
51
1.57
0.60
1.0
1.3
—
—
—
0
0
71
612
1.17
0.59
2.5
3.5
769.09
2453.54
u/ml
0.49
59
533
0
22
0.00
0.59
0.0
4.5
—
39.60
—
0
16
21
157
1.34
0.59
3.3
2.7
—
—
—
0
0
6
35
1.72
0.57
1.2
2.0
—
—
—
0
0
33
265
1.25
0.57
1.2
1.3
2.71
5.44
u/ml
1.18
14
107
6
37
1.62
0.55
1.0
1.2
0.33
3.70
%
—
6
30
6
38
1.58
0.54
1.2
1.1
—
—
—
0
0
151
1650
0.91
0.53
1.3
1.4
—
—
—
0
0
231
2153
1.08
0.53
1.3
1.3
—
—
—
0
0
22
169
1.31
0.53
1.1
1.2
—
—
—
0
0
52
442
1.18
0.53
1.2
1.2
—
—
—
0
0
38
457
0.83
0.52
1.0
1.1
—
—
—
0
0
12
84
1.43
0.49
1.1
1.1
1733.75
1650.12
miu/ml
0.10
12
84
34
281
1.21
0.47
3.0
2.7
9.55
7.39
mmol/l
0.83
34
270
24
299
0.80
0.47
1.2
1.2
326.62
275.55
u/ml
0.20
13
176
26
209
1.25
0.46
2.5
2.5
—
—
—
0
0
27
219
1.24
0.45
2.9
2.3
—
—
—
0
0
31
257
1.21
0.43
1.1
1.2
—
—
—
0
0
25
305
0.82
0.41
1.1
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
18
141
1.28
0.40
1.1
1.2
0.19
0.72
u/ml
0.98
12
72
0
18
0.00
0.40
0.0
8.1
—
8.22
—
0
18
0
18
0.00
0.40
0.0
4.1
—
44.61
—
0
18
25
303
0.82
0.39
1.1
1.1
—
—
—
0
0
7
103
0.68
0.39
1.1
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
5.0
—
7.39
—
0
19
43
372
1.16
0.39
1.7
1.3
11.72
11.35
u/l
0.05
33
297
15
115
1.31
0.39
1.5
2.0
0.88
2.27
u/field
—
8
64
69
620
1.12
0.37
1.6
2.0
19.60
20.68
s
1.59
58
551
33
382
0.86
0.33
1.2
1.4
3.26
41.40
e6/l
1.39
23
277
6
47
1.28
0.32
1.3
2.6
0.62
0.61
mmol/l
—
6
47
113
1213
0.93
0.31
1.6
1.7
—
—
—
0
0
12
93
1.29
0.30
1.9
2.5
8.71
8.62
mmol/l
0.03
12
93
31
269
1.16
0.29
1.1
1.8
—
—
—
0
0
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
8
64
1.25
0.27
2.9
2.2
147.00
153.72
nmol/l
—
8
58
34
385
0.88
0.27
1.3
1.4
593.84
1535.60
e6/l
0.48
25
295
16
131
1.22
0.27
1.1
1.0
—
—
—
0
0
9
74
1.22
0.25
1.9
1.3
198.56
391.94
u/l
—
9
68
26
298
0.87
0.25
5.9
3.8
19.44
23.21
mg/l
0.40
18
201
25
287
0.87
0.24
1.4
1.4
157.63
162.12
au/ml
—
8
71
19
162
1.17
0.23
1.2
1.1
—
—
—
0
0
5
42
1.19
0.21
1.4
3.1
6.20
5.19
ug/l
—
5
42
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.13
—
0
7
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
427
4368
0.97
0.20
1.4
1.4
—
—
—
0
0
51
470
1.09
0.20
1.2
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
208.80
—
0
5
0
14
0.00
0.20
0.0
2.0
—
37.29
—
0
14
120
1143
1.05
0.20
2.5
2.3
3.40
7.15
ug/l
7.48
101
1026
21
238
0.88
0.18
1.0
1.1
2.22
2.89
u/ml
0.21
13
112
172
1659
1.04
0.18
2.6
4.5
51.16
19.65
ug/l
0.46
135
1341
20
226
0.88
0.17
1.0
1.1
1.60
4.61
u/ml
1.47
12
94
22
196
1.12
0.16
1.1
1.3
—
—
—
0
0
18
158
1.14
0.16
3.4
2.0
4.29
7.28
umol/l
1.01
13
111
33
360
0.92
0.16
1.2
1.4
—
—
—
0
0
6
76
0.79
0.15
2.0
1.8
—
—
—
0
0
9
82
1.10
0.15
1.8
1.4
206.44
159.67
mmol/24h
—
9
82
29
316
0.92
0.14
1.4
1.4
—
—
—
0
0
10
84
1.19
0.14
1.6
1.5
26.60
31.53
umol/l
—
10
76
149
1444
1.03
0.13
1.4
1.4
—
—
—
0
0
82
856
0.96
0.13
1.1
1.1
—
—
—
0
0
19
171
1.11
0.12
4.1
5.4
18.78
51.83
u/ml
—
6
60
10
85
1.18
0.12
1.9
1.9
—
—
—
0
0
25
272
0.92
0.12
1.1
1.2
—
—
—
0
0
31
288
1.08
0.11
1.1
1.1
4.79
4.80
u/ml
0.00
19
147
13
147
0.88
0.11
1.0
1.2
—
—
—
0
0
14
124
1.13
0.11
1.3
1.2
—
—
—
0
0
13
146
0.89
0.10
5.1
3.5
12.25
12.09
index
—
8
91
32
341
0.94
0.10
1.1
1.1
0.74
1.93
u/ml
1.43
20
187
6
54
1.11
0.09
1.2
1.0
—
—
—
0
0
6
54
1.11
0.09
1.2
1.0
—
—
—
0
0
6
54
1.11
0.09
1.2
1.0
—
—
—
0
0
20
216
0.93
0.08
1.1
1.1
—
—
—
0
0
5
64
0.78
0.08
1.0
1.3
81.16
153.65
pmol/l
—
5
64
89
916
0.97
0.08
1.5
1.4
33.43
32.81
iu/l
0.06
68
788
7
65
1.08
0.08
1.0
1.0
—
9.31
—
0
12
80
776
1.03
0.08
1.1
1.1
—
90.61
—
0
18
11
98
1.12
0.07
1.1
1.3
151.36
134.25
nmol/l
0.28
11
98
8
91
0.88
0.06
5.6
3.8
0.75
0.81
index
—
8
91
27
284
0.95
0.06
2.4
2.0
—
—
—
0
0
26
272
0.96
0.04
1.0
1.1
1.32
1.70
u/ml
0.14
19
134
50
512
0.98
0.03
1.3
1.3
—
—
—
0
0
19
198
0.96
0.02
1.2
1.2
—
—
—
0
0
12
127
0.94
0.01
1.1
1.1
—
—
—
0
0
22
214
1.03
0.00
1.4
1.4
—
—
—
0
0
22
214
1.03
0.00
1.4
1.4
—
—
—
0
0
22
214
1.03
0.00
1.4
1.4
—
—
—
0
0
22
214
1.03
0.00
1.4
1.4
—
—
—
0
0
28
279
1.00
0.00
1.1
1.1
0.30
1.46
u/ml
1.61
19
118
16
156
1.03
0.00
1.5
2.2
—
—
—
0
0
35
346
1.01
0.00
1.8
1.8
43.20
40.85
nmol/l
0.15
35
334
19
187
1.02
0.00
1.4
1.6
—
—
—
0
0
20
203
0.99
0.00
1.0
1.1
0.03
0.30
u/ml
1.16
11
63
33
327
1.01
0.00
1.6
1.7
—
—
—
0
0
51
513
0.99
0.00
1.6
1.3
162.74
221.17
miu/ml
0.69
22
246
0
6
0.00
-0.00
0.0
1.2
—
84.00
—
0
6
0
9
0.00
-0.00
0.0
2.8
—
—
—
0
0
307
3070
1.00
-0.00
4.8
5.3
1.85
2.48
ug/l
1.39
272
2788
0
7
0.00
-0.00
0.0
5.3
—
378.00
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
42
420
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.8
—
104.67
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
27.72
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
3.39
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
2.62
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.2
2.2
16.80
27.68
%
—
5
44
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.2
—
844.44
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
0.79
—
0
5
6
64
0.94
-0.00
1.2
1.9
40.45
41.19
g/l
—
6
64
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_PSORI_PUSTUPALM and mortality.

Females

Parameter HR [95% CI] p-value
L12_PSORI_PUSTUPALM 1.24 [1.1, 1.4] < 0.001
Birth year 0.998 [0.99, 1.01] 0.688

During the follow-up period (1.1.1998 — 31.12.2019), 556 out of 5683 females with L12_PSORI_PUSTUPALM died.

Males

Parameter HR [95% CI] p-value
L12_PSORI_PUSTUPALM 1.432 [1.25, 1.64] < 0.001
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 387 out of 2303 males with L12_PSORI_PUSTUPALM died.

Mortality risk

Mortality risk for people of age

years, who have L12_PSORI_PUSTUPALM.

N-year risk Females Males
1 0.121% 0.28%
5 0.713% 1.631%
10 1.761% 4.463%
15 3.768% 8.079%
20 7.043% 14.014%

Relationships between endpoints

Index endpoint: L12_PSORI_PUSTUPALM – Pustulosis palmaris et plantaris

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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