No definition available.
Benign neoplasm: Pituitary gland, craniopharyngeal duct
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_PITUITARY_CRANIPHAR
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2308 |
4. Check minimum number of eventsNone |
2308 |
5. Include endpointsNone |
2308 |
6. Filter based on genotype QC (FinnGen only) |
2080 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Pituitary gland, craniopharyngeal duct
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and unspecified endocrine glands
- Benign neoplasms
- Used for control exclusion in common control thyroid runs
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10221 | 5749 | 4361 |
| Only index persons | 9206 | 5345 | 3861 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.16 | 0.12 |
| Only index persons | 0.18 | 0.20 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 50.74 | 47.54 | 55.24 |
| Only index persons | 49.72 | 46.32 | 54.42 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2080 | 1216 | 864 |
| Unadjusted period prevalence (%) | 0.42 | 0.43 | 0.40 |
| Median age at first event (years) | 51.67 | 48.10 | 56.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2162
- Matched controls
- 21620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D35.31
ICD-10 Finland
Cyst in Rathke's pocket
+∞
307.9
288
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
305.1
307.7
906
51
E22.1
ICD-10 Finland
Hyperprolactinaemia
141.2
307.7
466
42
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
2383.6
307.7
654
*
E23.00
ICD-10 Finland
Panhypopituitarism
591.9
307.7
391
8
ZXC86
NOMESCO Finland
Use of endoscopic device
119.7
307.7
206
19
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
292.8
307.7
258
10
H02AB09
ATC
hydrocortisone; systemic
58.7
307.7
740
190
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
4503599627370496.0
307.7
1857
*
N04BC06
ATC
cabergoline; oral
284.2
307.7
414
18
101
Kela drug reimbursment
Anterior pituitary hypofunction
126.4
307.7
402
39
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
563.3
302.7
294
6
G02CB01
ATC
bromocriptine; systemic
17.2
261.8
223
144
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
8.0
257.1
388
576
E23.05
ICD-10 Finland
Lack of TSH
90.6
244.0
128
15
XCK00
NOMESCO Finland
Perimetry
7.8
242.0
370
556
G02CB03
ATC
cabergoline; oral
48.4
226.0
132
29
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
14.3
221.3
208
160
H03AA01
ATC
levothyroxine sodium; systemic
4.2
220.5
905
3196
H53.4
ICD-10 Finland
Visual field defects
13.7
217.5
210
169
E23.2
ICD-10 Finland
Diabetes insipidus
98.2
180.8
94
10
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
592.7
168.6
165
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
7.3
154.0
240
363
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
16.4
151.6
130
84
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
7.8
149.5
219
309
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
507.5
145.2
143
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.5
144.4
218
318
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.4
137.3
396
1045
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.4
135.9
647
2406
ZXC95
NOMESCO Finland
Use of surgical navigator
13.8
131.4
124
95
102
Kela drug reimbursment
Diabetes insipidus
162.4
130.9
137
9
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
156.1
125.8
132
9
H01AC01
ATC
somatropin; parenteral
36.1
111.6
70
20
E23.03
ICD-10 Finland
Lack of ACTH
48.3
104.4
61
13
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
31.4
102.5
67
22
2273A
ICD-9 Finland
Benign neoplasm of other endocrine glands and related structures, Pituitary gland and craniopharyngeal duct (pouch)
+∞
101.9
97
*
D35.30
ICD-10 Finland
Craniopharyngoma
+∞
90.2
86
*
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
9.2
86.4
107
122
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
14.2
84.7
78
57
H01CB02
ATC
octreotide; parenteral
40.2
83.6
51
13
H01CB03
ATC
lanreotide; parenteral
45.6
82.7
49
11
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
11.2
79.5
85
79
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
74.2
476
2018
CS494
NOMESCO Finland
Other visual field testing
6.3
74.2
128
213
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
138.2
63.2
67
5
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
12.0
62.9
64
55
2542
FHL
Transasal hypophysectomy
+∞
60.7
58
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.0
59.9
298
1094
AA1AD
NOMESCO Finland
CT of head and brain
2.1
53.8
706
4027
301
Kela drug reimbursment
Growth hormone
117.0
53.0
57
5
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
51.7
301
1198
H47.2
ICD-10 Finland
Optic atrophy
16.0
51.3
44
28
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
8.6
50.3
65
78
Y28
ICPC
Limited function/disability (Y)
15.6
49.5
43
28
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
7.3
47.2
70
99
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
88.8
47.0
52
6
R51.80
ICD-10 Finland
Headache
2.2
46.7
457
2304
22620
ICD-8 Finland
Benign neoplasm of endocrine glands, Pituitary gland and craniopharyngeal duct (pouch)
+∞
46.0
44
*
WX882
NOMESCO Finland
High dependency care
4.8
45.1
104
225
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
45.0
630
3638
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
229.7
44.1
45
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.5
41.7
299
1312
T99
ICPC
Endocr/metab/nutrit disease other
5.9
41.6
75
130
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
11.9
40.4
41
35
9350/1-C75.2
ICD-O-3
Craniopharyngioma, NOS, of craniopharyngeal duct
+∞
39.7
38
*
E23.6
ICD-10 Finland
Other disorders of pituitary gland
87.8
38.9
43
5
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.6
38.8
136
401
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
38.6
275
1201
N91.1
ICD-10 Finland
Secondary amenorrhoea
5.7
37.8
71
128
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.6
37.6
72
132
G02CB04
ATC
quinagolide; oral
363.2
36.1
36
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
64.4
33.1
38
6
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
6.4
33.0
55
88
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.2
32.4
327
1651
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.8
32.2
176
673
UDM02
NOMESCO Finland
Sinoscopy
4.2
31.8
86
211
Z3231
NOMESCO Finland
Registered nurse
1.8
31.2
611
3862
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
10.1
31.0
35
35
2370A
ICD-9 Finland
Neoplasm of uncertain behaviour of endocrine glands and nervous system, Pituitary gland and craniopharyngeal duct
+∞
30.3
29
*
E22.9
ICD-10 Finland
Hyperfunction of pituitary gland, unspecified
+∞
29.2
28
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
28.4
310
1607
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.3
28.1
74
178
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
6.8
27.6
43
64
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.9
27.5
81
212
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
26.4
754
5250
E23
ICD-10 Finland
Hypofunction and other disorders of pituitary gland
94.6
25.7
28
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
21.5
24.8
36
17
H02AA02
ATC
fludrocortisone; oral
7.6
24.6
35
47
WVA30, ,
SPAT
2.4
23.8
172
751
E23.0
ICD-10 Finland
Hypopituitarism
87.8
23.7
26
*
G47.3
ICD-10 Finland
Sleep apnoea
1.7
23.5
523
3388
R42
ICD-10 Finland
Dizziness and giddiness
1.7
23.2
493
3152
E23.08
ICD-10 Finland
Hypopituitarism
84.4
22.7
25
*
WX402
NOMESCO Finland
General anaesthesia
1.7
22.4
516
3368
25320
ICD-8 Finland
Diseases of pituitary gland, Chromophobe adenoma, pituitary
+∞
21.9
21
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
21.9
204
992
G44.2
ICD-10 Finland
Tension-type headache
1.9
21.8
327
1881
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.5
21.2
72
208
TAB00
NOMESCO Finland
Lumbar puncture
2.6
21.1
125
497
D352, E221,
ICD-10 Finland
+∞
20.9
20
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
20.9
1564
13386
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
20.6
158
708
ZXA10
NOMESCO Finland
Bilateral
1.8
20.2
376
2306
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
19.9
968
7499
2530A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Acromegaly and gigantism[ACROMEGALIA]
+∞
19.8
19
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
29.2
19.6
26
9
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
40.5
19.5
24
6
T73
ICPC
Neoplasm endocrine other/unspecified
34.6
18.9
24
7
E27.2
ICD-10 Finland
Addisonian crisis
70.5
18.7
21
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
23.9
18.6
26
11
V04CD01
ATC
metyrapone; oral
100.9
18.6
20
*
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
16.3
18.3
29
18
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
18.3
426
2771
A02BC02
ATC
pantoprazole; systemic
1.5
18.2
1423
12076
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
33.2
18.0
23
7
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
6.7
17.9
28
42
E23.7
ICD-10 Finland
Disorder of pituitary gland, unspecified
67.2
17.7
20
*
AA4DM
NOMESCO Finland
Very extensive MRI examination of sella turcica with 3 Tesla magnet
+∞
17.7
17
*
D35.9
ICD-10 Finland
Benign neoplasm: Endocrine gland, unspecified
181.4
17.5
18
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
3.5
17.2
59
172
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.3
17.1
64
197
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
17.1
747
5611
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
19.4
16.9
25
13
A55
ICPC
General and Unspecified, Local injection/infiltration
4.2
16.8
44
106
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
16.8
404
2647
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
16.3
155
758
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
16.2
141
667
N02BE01
ATC
paracetamol; systemic, rectal
1.7
16.1
1891
17299
N75
ICPC
Benign neoplasm nervous system
47.9
16.0
19
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
6.9
15.7
24
35
D35.3
ICD-10 Finland
Benign neoplasm: Craniopharyngeal duct
+∞
15.6
15
*
E66.8
ICD-10 Finland
Other obesity
2.2
15.6
139
663
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
15.1
14.9
24
16
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
14.8
169
884
N04BC01
ATC
bromocriptine; oral
57.1
14.8
17
*
E21.0
ICD-10 Finland
Primary hyperparathyroidism
3.5
14.7
51
150
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
25.2
14.7
20
8
-50
ICPC
Medication/prescr/renewal
2.5
14.6
93
384
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
14.5
861
6807
H47.4
ICD-10 Finland
Disorders of optic chiasm
151.0
14.5
15
*
UJF32
NOMESCO Finland
Coloscopy
1.5
14.2
506
3615
E29.1
ICD-10 Finland
Testicular hypofunction
3.9
14.1
41
107
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
6.1
13.9
24
40
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
13.8
373
2504
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
3.7
13.7
43
118
H53.1
ICD-10 Finland
Subjective visual disturbances
2.0
13.7
154
801
2159
FHL
Other measure in this category
75.6
13.6
15
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.8
13.6
195
1102
D35.50
ICD-10 Finland
Carotid body
+∞
13.6
13
*
2532A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Panhypopituitarism[PANHYPOPITUITARISMUS]
140.9
13.5
14
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.7
13.4
41
111
R55
ICD-10 Finland
Syncope and collapse
1.8
13.1
210
1227
R53
ICD-10 Finland
Malaise and fatigue
1.5
13.1
526
3846
2531A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Other and unspecified anterior pituitary hyperfunction[HYPERPROLACTINAEMIA]
50.3
12.8
15
*
H53.2
ICD-10 Finland
Diplopia
2.5
12.8
79
321
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
3.4
12.8
45
134
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
12.7
566
4219
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
17.4
12.5
19
11
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
12.5
459
3290
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
12.5
778
6160
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.3
12.5
46
141
AA4AD
NOMESCO Finland
CT of sella turcica
130.7
12.4
13
*
WF099
NOMESCO Finland
Other radiotherapy
5.7
12.4
23
41
E03.89
ICD-10 Finland
Other specified hypothyroidism
2.3
12.3
89
390
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
3.9
12.3
35
90
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
5.8
12.3
22
38
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
12.2
322
2143
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
37.8
12.2
15
*
E24.8
ICD-10 Finland
Other Cushing syndrome
21.4
12.0
17
8
G03DB01
ATC
dydrogesterone; oral
1.7
12.0
246
1540
ZX050
NOMESCO Finland
Stereotactic radiotherapy
4.7
11.9
27
58
J01DB01
ATC
cefalexin; oral
1.5
11.8
1730
15779
AA4BD
NOMESCO Finland
Extensive CT of sella turcica
+∞
11.5
11
*
AA4BM
NOMESCO Finland
MRI examination of sella turcica with 3 Tesla magnet
+∞
11.5
11
*
N06AB10
ATC
escitalopram; oral
1.5
11.4
425
3048
R11
ICD-10 Finland
Nausea and vomiting
1.8
10.9
183
1082
SPAT1254
SPAT
Administration of medicine
1.6
10.7
272
1792
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
10.7
204
1251
E89.39
ICD-10 Finland
Postprocedural hypopituitarism, other or several procedures
60.3
10.6
12
*
R5140
NOMESCO Finland
Monitoring the use of the aid
1.6
10.5
225
1423
R51
ICD-10 Finland
Headache
1.9
10.5
129
694
H01AX01
ATC
pegvisomant; parenteral
+∞
10.4
10
*
M14.5*E22.0
ICD-10 Finland
Arthropathy associated with acromegaly
+∞
10.4
10
*
E22
ICD-10 Finland
Hyperfunction of pituitary gland
+∞
10.4
10
*
N64.3
ICD-10 Finland
Galactorrhoea not associated with childbirth
5.4
10.4
20
37
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
5.4
10.4
20
37
XA800
NOMESCO Finland
Neuropsychological investigation
2.1
10.2
93
449
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
10.1
596
4638
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
5.3
10.1
20
38
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
7.9
10.1
22
28
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
10.1
237
1533
N06AX21
ATC
duloxetine; oral
1.6
10.0
247
1618
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
9.8
728
5878
UKC02
NOMESCO Finland
Cystoscopy
1.6
9.7
275
1857
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.0
9.7
100
506
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
9.7
183
1120
WF002
NOMESCO Finland
Radical radiotherapy
2.0
9.6
105
542
T28
ICPC
Limited function/disability (T)
3.9
9.6
27
69
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.7
9.6
50
188
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
9.4
180
1104
9350/1-C75.1
ICD-O-3
Craniopharyngioma, NOS, of pituitary gland
+∞
9.4
9
*
D352, E220,
ICD-10 Finland
+∞
9.4
9
*
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
21.8
9.3
13
6
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
9.3
1103
9518
S10
ICPC
Boil/carbuncle
1.8
9.2
126
701
N03AX14
ATC
levetiracetam; systemic
2.4
9.1
60
253
R93.0
ICD-10 Finland
Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
11.5
9.1
16
14
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
9.0
129
728
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.3
8.9
66
293
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
8.9
250
1686
R06.0
ICD-10 Finland
Dyspnoea
1.4
8.8
509
3936
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
8.7
148
880
L28
ICPC
Limited function/disability (L)
1.5
8.7
333
2395
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
4.0
8.6
24
61
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.1
8.6
84
417
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
8.6
118
658
A02BC05
ATC
esomeprazole; systemic
1.3
8.6
765
6317
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
8.5
260
1783
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
8.5
90
460
SPAT1240
SPAT
Therapeutic discussion
1.6
8.5
211
1382
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
2.5
8.4
52
213
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
7.9
8.4
18
23
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
8.3
1098
9553
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.7
8.3
136
799
E22.88
ICD-10 Finland
Other hyperfunction of pituitary gland
+∞
8.3
8
*
25300
ICD-8 Finland
Diseases of pituitary gland, Aeromegalia
+∞
8.3
8
*
25310
ICD-8 Finland
Diseases of pituitary gland, Panhypopituitarismus
+∞
8.3
8
*
2550C
ICD-9 Finland
Disorders of adrenal glands, Cushing's syndrome[SYNDROMA CUSHING E HYPERSECRETIO HYPOFYSEOS]
+∞
8.3
8
*
2549, ,
FHL
+∞
8.3
8
*
E2300, D352,
ICD-10 Finland
+∞
8.3
8
*
C10AA07
ATC
rosuvastatin; oral
1.3
8.3
613
4919
XX9XW, ,
NOMESCO Finland
4.1
8.3
22
54
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
8.2
167
1041
183
Kela drug reimbursment
Lamotrigin and topiramate
3.9
8.2
23
59
R01AD08
ATC
fluticasone; nasal
1.4
8.1
555
4400
XCH00
NOMESCO Finland
Eye pressure measurement
2.0
8.0
90
470
C08CA01
ATC
amlodipine; oral
1.3
8.0
661
5386
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
22.1
8.0
11
5
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.2
8.0
65
301
G43.9
ICD-10 Finland
Migraine, unspecified
1.7
7.9
134
796
R01AD09
ATC
mometasone; nasal
1.3
7.9
903
7690
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.2
7.9
65
303
N03AX11
ATC
topiramate; oral
2.3
7.8
55
239
A02BC01
ATC
omeprazole; systemic
1.4
7.7
482
3763
R04
ICPC
Breathing problem other
2.0
7.7
78
393
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
7.7
585
4708
N17
ICPC
Vertigo/dizziness
1.5
7.7
237
1630
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.6
702
5805
E22.2
ICD-10 Finland
Syndrome of inappropriate secretion of antidiuretic hormone
11.9
7.6
13
11
2397A
ICD-9 Finland
Neoplasm of unspecified nature, Endocrine glands and other parts of nervous system
25.1
7.6
10
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
7.5
113
648
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
7.5
842
7138
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
7.5
188
1234
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
7.5
260
1830
SPAT1153
SPAT
Removal of sutures
1.3
7.5
558
4472
SPAT1301
SPAT
No procedures
1.3
7.5
556
4456
ZXE30
NOMESCO Finland
More than five and less than seven hours
1.9
7.4
84
440
BCA41
NOMESCO Finland
Endoscopic bilateral adrenalectomy
80.4
7.4
8
*
D35.6
ICD-10 Finland
Benign neoplasm: Aortic body and other paraganglia
80.4
7.4
8
*
E24
ICD-10 Finland
Cushing syndrome
80.4
7.4
8
*
Z71.8
ICD-10 Finland
Other specified counselling
1.3
7.4
678
5595
M79.6
ICD-10 Finland
Pain in limb
1.3
7.4
862
7344
N03AX09
ATC
lamotrigine; oral
1.8
7.4
101
564
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
8.4
7.3
15
18
D44.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Craniopharyngeal duct
+∞
7.3
7
*
23990
ICD-8 Finland
Neoplasm of unspecified nature of other and unspecified organs, Glandulae pituitariae et ductus craniopharyngice
+∞
7.3
7
*
E23.3
ICD-10 Finland
Hypothalamic dysfunction, not elsewhere classified
+∞
7.3
7
*
E24.1
ICD-10 Finland
Nelson syndrome
+∞
7.3
7
*
8272/3-C75.1
ICD-O-3
Pituitary carcinoma, NOS, of pituitary gland
+∞
7.3
7
*
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
7.3
7
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
3.5
7.3
24
69
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
7.2
278
1997
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.6
7.2
39
150
Z2445
NOMESCO Finland
Psychologist
2.0
7.2
80
417
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
2.5
7.2
43
174
AA4WT
NOMESCO Finland
Selective blood sample from sinus petrosus inferior
30.1
7.1
9
*
R41.3
ICD-10 Finland
Other amnesia
2.3
7.1
54
243
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
7.1
194
1298
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
2.8
7.1
35
128
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
6.0
7.1
18
30
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
7.0
128
776
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
7.0
252
1786
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.4
7.0
44
182
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
2.5
7.0
41
164
G93.0
ICD-10 Finland
Cerebral cysts
5.8
6.9
18
31
Y99
ICPC
Genital disease male other
7.5
6.9
15
20
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.9
497
3960
C09CA06
ATC
candesartan; oral
1.3
6.9
449
3525
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.8
497
3966
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.8
1036
9091
XLA10, ,
NOMESCO Finland
1.9
6.8
84
455
D35.59
ICD-10 Finland
Other paragangliom
40.2
6.8
8
*
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
40.2
6.8
8
*
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
16.7
6.7
10
6
BCA30
NOMESCO Finland
Unilateral adrenalectomy
16.7
6.7
10
6
N76
ICPC
Neoplasm nervous system unspecified
16.7
6.7
10
6
ZXE00
NOMESCO Finland
One hour or less
1.3
6.7
717
6019
A04
ICPC
Weakness/tiredness general
1.4
6.7
302
2231
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.3
6.7
48
211
S50
ICPC
Skin, Medication/prescr/renewal
3.9
6.7
19
49
C07AA05
ATC
propranolol; systemic
1.4
6.7
385
2963
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.8
6.7
88
486
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.7
501
4013
H93.1
ICD-10 Finland
Tinnitus
1.7
6.7
129
796
D06
ICPC
Abdominal pain localized other
1.6
6.6
170
1124
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
6.6
461
3655
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
6.5
271
1973
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.5
839
7203
N01
ICPC
Headache
1.5
6.5
228
1611
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
2.7
6.4
32
118
P20
ICPC
Memory disturbance
1.5
6.4
211
1469
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.5
6.4
21
60
C03DA01
ATC
spironolactone; oral
1.5
6.4
201
1386
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
6.4
541
4403
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
6.3
282
2079
SPAT1263
SPAT
Sampling
1.3
6.3
768
6541
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
6.3
252
1822
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
6.3
172
1152
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
6.3
232
1652
C08CA13
ATC
lercanidipine; oral
1.4
6.3
240
1721
PA2AD
NOMESCO Finland
CT angiography of brain
3.3
6.3
23
71
DFF00
NOMESCO Finland
Pure tone audiometry
1.5
6.3
182
1236
C75.1
ICD-10 Finland
Malignant neoplasm: Pituitary gland
+∞
6.3
6
*
E220, D352,
ICD-10 Finland
+∞
6.3
6
*
D352, E2300,
ICD-10 Finland
+∞
6.3
6
*
AA4CD
NOMESCO Finland
Very extensive CT of sella turcica
+∞
6.3
6
*
E22.80
ICD-10 Finland
Central precocious puberty
+∞
6.3
6
*
8240/3-C25.9
ICD-O-3
Neuroendocrine tumor, NOS, of pancreas, NOS
26.7
6.2
8
*
2250A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
26.7
6.2
8
*
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.2
1191
10688
104
Kela drug reimbursment
Thyroid insufficiency
1.7
6.2
119
733
N97.0
ICD-10 Finland
Female infertility associated with anovulation
2.5
6.2
38
156
A28
ICPC
Limited function/disability NOS
1.4
6.1
280
2073
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
6.1
397
3108
ZZC00
NOMESCO Finland
Graft of fascia
12.6
6.1
10
8
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
12.6
6.1
10
8
ZXD05
NOMESCO Finland
Urgent procedure
1.3
6.0
550
4514
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
614
1213
6.67
313.51
2.0
1.4
19.77
25.07
iu/l
3.44
502
1034
1156
131
188.50
307.65
3.4
1.6
16.97
21.17
nmol/l
4.67
1142
120
1611
1924
29.93
307.65
6.0
2.1
358.07
380.33
nmol/l
2.60
1574
1786
405
256
19.24
307.65
4.4
1.4
460.97
336.43
mu/l
1.28
385
204
708
654
15.61
307.65
2.2
1.4
7.30
9.60
u/l
3.26
577
530
1293
838
36.90
307.65
5.0
1.4
381.31
288.85
mu/l
3.53
1271
763
771
1686
6.55
307.65
6.0
2.3
12.29
13.14
nmol/l
2.02
745
1535
180
114
17.13
212.79
1.4
1.7
—
—
—
0
0
167
100
18.01
202.91
2.8
1.7
3.00
3.98
nmol/l
0.20
143
82
273
383
8.01
188.20
2.0
1.5
0.31
0.39
nmol/l
1.28
195
311
310
517
6.83
182.28
3.3
1.9
169.20
207.54
pmol/l
6.32
295
489
497
1278
4.75
181.23
3.5
3.6
4.37
4.55
pmol/l
2.90
473
1146
195
222
9.56
158.79
2.5
1.4
286.22
279.68
mosm/kgh2o
2.48
179
168
2006
14944
5.74
117.93
8.9
4.5
14.94
14.67
pmol/l
5.34
1968
13876
99
67
15.44
112.35
3.4
1.4
162.60
487.45
nmol/24h
0.36
99
67
1442
9377
2.61
94.86
8.3
7.3
1.21
1.21
mmol/l
0.01
1260
8150
1333
8382
2.54
93.72
7.5
6.7
1.21
1.21
mmol/l
0.01
1261
7776
1520
11152
2.22
61.26
6.4
5.2
6.44
6.63
mmol/l
3.62
1466
10535
459
2169
2.42
55.50
7.4
8.6
5.11
5.09
kpa
0.16
438
2083
459
2170
2.42
55.44
7.4
8.6
14.98
12.35
kpa
12.13
437
2087
456
2152
2.42
55.28
7.3
8.5
0.74
0.87
mmol/l
0.37
337
1753
132
324
4.27
48.90
2.2
1.3
16.26
23.78
u/l
2.37
122
269
2023
17510
3.42
47.11
8.5
5.4
1.54
1.88
mu/l
33.74
1928
16392
159
473
3.55
44.86
1.5
1.4
140.88
44.43
e6/l
0.53
116
353
160
479
3.53
44.70
1.5
1.5
1229.34
1091.58
e6/l
0.08
125
374
54
68
8.12
40.16
1.6
1.5
14.26
14.23
pmol/l
0.01
49
56
1193
8809
1.79
37.58
3.1
2.5
76.64
76.34
nmol/l
0.15
1117
8046
2080
18794
3.81
35.25
25.8
17.7
139.97
139.65
mmol/l
8.99
2071
18455
87
203
4.42
34.36
1.7
1.7
—
—
—
0
0
1136
8402
1.74
34.33
5.3
5.2
36.02
36.01
g/l
0.02
1084
7924
2080
18834
3.75
34.28
25.8
17.9
3.92
3.96
mmol/l
14.73
2068
18468
842
5828
1.73
31.44
2.3
2.2
190.43
208.51
u/l
0.27
803
5546
152
545
2.92
31.34
1.3
1.3
529.58
530.23
mg/l
0.01
146
518
737
4923
1.75
31.18
4.1
4.2
92.98
90.69
%
1.66
719
4819
139
485
2.99
30.08
1.2
1.3
3.41
3.76
mmol/l
5.08
128
459
90
251
3.70
27.90
1.4
1.4
1443.00
350.34
pmol/l
0.48
79
216
87
238
3.77
27.73
1.7
1.3
0.18
0.25
nmol/l
0.42
67
185
1105
8408
1.64
27.59
13.0
14.0
1.19
1.22
inr
1.19
943
7014
1989
17933
2.36
26.71
20.0
14.6
84.26
84.03
ml/min/173m2
0.20
1895
16557
1659
14115
1.75
26.06
4.7
4.4
11.31
11.36
mm/h
0.05
1593
13274
1694
14527
1.77
25.53
8.8
8.3
76.03
77.79
u/l
0.93
1630
13850
48
87
5.62
25.42
2.0
1.9
—
—
—
0
0
474
2932
1.79
25.30
1.8
2.2
29.01
29.46
s
1.12
462
2847
323
1812
1.92
23.40
9.2
9.4
126.34
122.04
g/l
3.72
311
1767
1249
10061
1.57
22.60
6.1
6.6
10.52
11.38
umol/l
3.08
1193
9615
240
1243
2.05
21.80
8.4
10.6
94.90
93.96
%
1.46
240
1237
234
1201
2.06
21.78
8.5
10.8
0.70
0.64
%
1.76
234
1195
268
1445
1.98
21.74
3.8
3.8
1.23
1.23
mmol/l
0.05
243
1245
335
1945
1.85
21.72
8.8
8.9
96.42
95.72
%
1.12
322
1884
410
2536
1.76
21.52
5.4
6.2
1.00
1.04
mmol/l
2.96
397
2354
239
1247
2.03
21.25
8.4
10.4
1.16
1.30
%
2.01
239
1241
97
337
2.97
21.15
2.0
2.0
4.69
5.15
mmol/24h
0.73
91
302
1092
8700
1.52
19.56
13.8
11.2
0.00
0.00
e9/l
0.59
928
7128
1340
11168
1.53
19.22
8.7
9.7
4.08
4.09
e9/l
0.06
1185
9730
2014
18643
2.17
18.86
18.7
15.5
20.87
23.21
mg/l
3.35
1757
15366
2095
19769
2.93
18.07
26.6
19.5
77.31
76.23
umol/l
0.83
2087
19582
1914
17477
1.83
17.71
7.0
6.1
38.58
38.86
mmol/mol
0.73
1834
16492
420
2764
1.64
17.15
2.4
2.6
22.73
23.18
%
0.29
398
2580
449
3019
1.61
16.78
2.4
2.6
2.30
2.34
g/l
0.71
419
2802
1246
10392
1.47
16.57
6.3
6.7
0.19
0.19
e9/l
0.26
1106
9136
692
5152
1.50
16.33
2.4
2.3
2.78
2.77
mg/l
0.07
614
4459
1173
9700
1.46
16.10
3.5
3.2
112.18
113.91
ug/l
0.14
1110
9137
1934
17838
1.80
15.60
5.7
4.9
5.76
5.88
mmol/l
5.09
1850
16519
471
3259
1.57
15.44
2.5
2.6
12.83
13.48
umol/l
1.20
449
3040
1228
10289
1.45
15.43
6.2
6.5
1.96
1.95
e9/l
0.08
1102
9123
465
3224
1.56
15.07
3.7
3.5
0.83
0.82
mmol/l
0.57
445
3060
838
6569
1.45
14.89
3.4
3.5
2.35
2.35
mmol/l
0.57
770
6009
792
6154
1.45
14.69
3.5
3.4
80.22
64.40
e6/l
0.31
615
4698
785
6095
1.45
14.60
2.8
2.7
59.58
72.95
u/l
0.50
720
5671
644
4815
1.48
14.54
2.7
2.4
—
—
—
0
0
1023
8347
1.43
14.48
2.2
2.1
95.50
96.50
pmol/l
0.28
573
4538
37
88
4.26
14.35
1.2
1.4
140.46
170.77
mmol/24h
1.59
37
88
697
5312
1.46
14.20
3.5
3.2
0.32
0.40
e6/l
0.52
524
3893
24
18
13.47
14.20
1.8
1.3
4.24
13.03
pmol/l
1.44
19
18
1094
9109
1.41
13.41
3.1
2.8
—
—
estimate
—
0
0
872
6983
1.42
13.36
3.8
3.7
28.18
53.55
ng/l
1.64
588
4691
61
215
2.89
13.05
1.1
1.1
—
—
—
0
0
635
4822
1.45
12.95
1.4
1.3
1.41
1.60
u/ml
0.14
175
1338
275
1746
1.66
12.68
8.0
8.1
1.26
1.32
mmol/l
0.38
266
1710
1417
12402
1.41
12.62
5.1
4.6
3455.52
1804.73
e6/l
0.34
21
171
974
8063
1.38
11.78
2.0
1.9
1.46
1.37
mmol/l
2.62
850
6887
564
4257
1.44
11.67
2.8
2.7
5.16
6.01
e6/l
0.98
518
3887
231
1433
1.69
11.61
4.4
4.0
76.78
87.56
ng/l
1.38
203
1264
670
5236
1.41
11.35
2.7
3.1
1150.17
1160.57
ng/l
0.02
567
4442
1203
10342
1.37
11.29
4.0
3.8
0.00
0.16
estimate
0.53
303
2043
432
3132
1.47
10.96
1.9
1.9
—
—
—
0
0
1183
10171
1.36
10.94
4.0
3.8
0.00
0.00
estimate
0.50
312
2144
1731
15866
1.46
10.75
24.7
18.9
13.57
13.55
%
0.28
1720
15672
1193
10291
1.36
10.69
4.0
3.8
3.85
5.26
estimate
0.13
313
2179
679
5367
1.39
10.61
1.8
1.7
19.50
20.23
nmol/l
0.68
601
4594
278
1886
1.54
9.62
3.6
3.2
—
—
—
0
0
544
4210
1.39
9.47
1.5
1.5
2.28
2.39
g/l
0.74
346
2676
1873
17543
1.51
9.41
4.8
4.2
1.39
1.28
mmol/l
4.99
1767
16311
198
1261
1.63
8.97
3.2
3.7
5.01
5.17
kpa
2.51
188
1211
182
1143
1.65
8.71
8.7
7.1
24.41
24.43
mmol/l
0.03
170
1089
2104
20368
2.23
8.68
31.1
23.4
254.69
252.83
e9/l
0.65
2083
20016
2104
20374
2.22
8.57
30.9
23.3
90.61
90.88
fl
2.30
2097
20195
43
159
2.74
8.53
1.1
1.1
—
—
—
0
0
2104
20377
2.21
8.52
31.6
23.9
40.79
40.51
%
2.39
2097
20187
2104
20377
2.21
8.52
31.0
23.4
4.53
4.51
e12/l
1.02
2079
19975
2104
20381
2.21
8.44
31.1
23.5
6.82
6.76
e9/l
0.34
2080
19972
2104
20384
2.20
8.39
31.3
23.6
135.68
135.73
g/l
0.05
2096
20207
1942
18422
1.53
8.18
5.6
4.9
1.39
1.45
mmol/l
9.99
1850
17279
44
170
2.62
8.03
1.2
1.1
34.72
39.91
mg/l
0.64
38
135
37
133
2.81
7.76
1.2
1.2
0.57
0.57
ratio
0.01
18
74
104
582
1.83
7.53
2.2
2.1
2.35
4.16
iu/l
3.26
47
243
1945
18511
1.51
7.47
5.7
4.9
4.61
4.65
mmol/l
0.95
1857
17473
1963
18725
1.53
7.38
6.3
5.5
2.75
2.73
mmol/l
0.46
1874
17597
244
1706
1.48
7.29
6.1
7.9
8.09
9.43
mmol/l
2.90
236
1645
458
3582
1.35
7.22
3.5
3.8
226.62
446.85
ng/l
0.83
321
2647
675
5585
1.30
7.17
4.1
4.0
0.01
0.00
estimate
0.29
302
2015
391
2987
1.38
7.15
1.8
1.7
1092.09
1177.14
nmol/l
1.18
312
2290
230
1598
1.49
7.08
2.9
2.9
10.44
10.79
g/l
0.62
204
1473
104
594
1.79
7.06
3.0
3.9
1.39
1.48
mg/l
0.71
97
542
685
5692
1.30
7.02
3.6
3.2
0.02
0.06
estimate
0.65
252
1728
219
1511
1.50
6.98
1.2
1.2
146.31
146.11
u/ml
0.00
83
586
2039
19654
1.66
6.92
13.6
11.9
28.04
26.32
u/l
1.53
2002
19175
166
1080
1.58
6.91
10.6
11.3
16.58
16.01
%
1.77
157
1034
794
6738
1.28
6.88
3.2
3.3
35.38
31.56
u/l
0.58
754
6376
260
1865
1.45
6.80
2.4
2.3
0.22
0.21
g/l
0.19
247
1743
204
1397
1.51
6.74
2.7
2.4
14.53
21.97
au/ml
0.79
12
153
36
138
2.64
6.72
1.1
1.0
1.33
1.10
u/l
0.40
15
63
74
386
1.95
6.67
3.1
2.6
17.11
16.51
%
0.95
74
377
231
1626
1.47
6.67
2.5
2.9
70.96
70.69
e9/l
0.04
169
1200
190
1286
1.52
6.63
1.4
1.3
67.82
53.36
au/ml
0.28
12
91
26
84
3.12
6.59
1.1
1.1
12.67
249.13
ng/l
—
6
22
117
706
1.69
6.57
1.6
1.7
—
—
—
0
0
140
886
1.62
6.54
1.9
2.0
37.65
39.69
u/l
0.56
130
796
673
5629
1.28
6.45
6.2
5.3
1.71
2.46
ug/l
3.25
619
5103
164
1084
1.56
6.38
3.2
3.5
1.76
1.76
mmol/l
0.01
111
815
30
108
2.80
6.32
1.1
1.1
—
—
—
0
0
390
3043
1.34
6.17
3.2
3.1
2.59
2.43
e6/l
0.12
182
1477
15
24
6.29
6.16
1.2
1.7
—
—
—
0
0
217
1535
1.46
6.11
2.7
2.9
66.29
66.75
g/l
0.41
208
1428
310
2345
1.38
5.97
1.8
1.8
—
—
—
0
0
208
1478
1.45
5.73
2.6
2.8
72.95
69.37
ml/min/173m2
0.63
85
617
888
7760
1.24
5.69
3.9
3.7
0.01
0.03
estimate
0.96
271
1792
461
3723
1.30
5.69
3.1
2.9
2.44
2.44
mmol/l
0.09
418
3346
1383
12695
1.25
5.61
3.4
3.2
—
—
—
0
0
140
928
1.54
5.41
2.4
2.3
12083.91
5622.38
u/l
0.66
33
372
1449
13406
1.25
5.31
3.8
3.4
46.29
46.29
u/l
0.00
1381
12711
342
2676
1.33
5.27
2.0
2.6
88.43
123.39
ug/g
2.16
266
2147
5
0
+∞
5.21
1.0
0.0
327.80
—
nmol/l
—
5
0
15
40
3.77
5.09
1.1
1.3
—
—
—
0
0
13
23
5.68
5.06
2.1
1.0
5.44
5.59
nmol/l
0.05
13
23
411
3318
1.29
5.04
3.1
2.9
1.08
0.97
e6/l
0.18
205
1754
194
1395
1.43
5.03
1.8
1.7
—
—
—
0
0
102
642
1.62
4.94
1.9
1.8
—
—
—
0
0
89
544
1.66
4.84
1.5
1.3
—
—
—
0
0
110
709
1.58
4.84
2.1
1.9
—
—
—
0
0
113
733
1.57
4.83
2.8
2.5
3.71
3.68
g/l
0.05
106
678
113
733
1.57
4.83
2.8
2.5
4.11
4.25
g/l
1.28
106
678
113
733
1.57
4.83
2.8
2.5
7.14
7.29
g/l
0.42
105
678
144
986
1.49
4.81
1.4
1.5
—
—
—
0
0
287
2224
1.33
4.72
1.8
1.9
—
—
—
0
0
296
2310
1.33
4.63
2.4
2.8
5.83
7.86
umol/l
2.17
253
2044
107
693
1.57
4.62
2.8
2.5
2.69
2.92
g/l
1.73
99
639
533
4486
1.25
4.60
1.8
1.8
1.02
1.15
mg/l
0.43
410
3419
8
8
10.03
4.52
2.0
1.1
2.04
2.26
nmol/l
—
8
8
250
1912
1.35
4.49
4.0
3.6
5.82
5.83
kpa
0.08
243
1852
280
2179
1.33
4.47
4.0
4.4
227.08
245.95
u/l
1.76
267
2079
253
1944
1.34
4.40
2.2
2.5
128.07
40.90
u/l
0.45
218
1629
20
71
2.83
4.39
1.2
1.2
108.80
105.38
%
0.22
20
60
48
252
1.93
4.36
1.3
1.4
—
—
—
0
0
17
55
3.11
4.36
1.2
1.1
—
—
—
0
0
17
55
3.11
4.36
1.2
1.1
—
—
—
0
0
32
144
2.24
4.35
1.0
1.1
1.62
3.29
nmol/l
—
10
25
123
837
1.50
4.27
8.8
5.6
1.46
1.59
%
1.21
113
785
21
78
2.71
4.25
1.2
1.1
0.33
0.29
g/l
0.97
14
65
9
13
6.95
4.16
1.0
1.2
—
—
—
0
0
96
623
1.57
4.14
1.5
1.8
0.25
0.23
g/l
0.78
89
590
17
58
2.95
4.01
1.1
1.2
—
—
—
0
0
37
183
2.04
3.99
6.2
4.0
49.69
54.88
%
0.60
27
165
97
638
1.54
3.96
2.9
2.5
9.42
10.40
g/l
1.79
88
580
84
536
1.59
3.91
1.9
2.2
9.65
11.45
mg/l
1.81
78
503
9
15
6.02
3.81
1.0
1.1
—
—
—
0
0
238
1852
1.32
3.81
4.2
3.7
1.95
1.81
mmol/l
0.24
201
1601
97
645
1.53
3.78
1.5
1.8
1.26
1.19
g/l
1.87
91
611
82
528
1.57
3.69
1.8
1.7
—
—
—
0
0
156
1144
1.39
3.67
1.7
1.7
—
—
—
0
0
16
56
2.87
3.63
1.1
1.1
—
—
—
0
0
169
1259
1.37
3.62
1.8
1.9
1.26
1.37
g/l
0.37
159
1163
409
3435
1.24
3.53
3.6
3.2
0.78
0.74
ug/l
0.17
288
2154
527
4543
1.21
3.52
4.7
4.3
22.04
21.34
%
0.51
246
2115
84
551
1.55
3.51
3.0
2.4
0.00
0.02
g/l
1.12
76
501
68
425
1.62
3.48
1.8
2.2
0.91
0.90
nmol/l
0.07
62
364
456
3886
1.22
3.41
1.7
1.7
442.26
31389061.62
pmol/l
3.47
384
3291
95
645
1.49
3.39
3.0
2.6
0.33
1.15
g/l
3.21
84
566
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
24
107
2.26
3.39
1.1
1.1
—
—
—
0
0
117
829
1.43
3.37
1.3
1.2
0.21
1.17
u/ml
—
9
62
206
1610
1.31
3.22
3.5
3.1
4.48
4.57
kpa
0.33
200
1559
19
78
2.45
3.21
1.0
1.1
—
—
—
0
0
12
34
3.54
3.19
1.3
1.1
—
—
—
0
0
81
541
1.52
3.15
2.9
2.4
0.00
0.00
g/l
-0.00
73
477
76
505
1.52
3.04
2.8
3.3
2.08
1.97
index
0.08
37
266
14
51
2.76
2.98
2.0
2.2
19.51
16.68
umol/l
0.36
14
51
10
26
3.86
2.98
1.0
1.0
—
—
—
0
0
8
17
4.72
2.92
1.0
1.1
—
—
—
0
0
14
52
2.70
2.89
1.2
1.1
—
—
—
0
0
24
115
2.10
2.88
1.3
1.5
1.51
1.29
nmol/l
0.38
18
85
565
4983
1.18
2.87
2.5
2.8
339.51
338.84
umol/l
0.06
496
4431
92
644
1.45
2.87
2.0
2.3
90.94
93.12
%
0.38
87
624
22
103
2.15
2.80
1.4
1.3
—
—
—
0
0
47
284
1.67
2.80
5.6
4.1
0.95
1.43
%
0.70
38
262
64
418
1.55
2.79
3.1
3.1
32.27
33.35
umol/l
0.14
59
380
97
692
1.42
2.74
3.1
3.8
24.85
24.84
mmol/l
0.00
85
642
29
153
1.91
2.70
1.8
1.5
38.70
31.01
%
0.49
23
93
14
54
2.60
2.70
1.1
1.1
—
—
—
0
0
9
24
3.76
2.67
1.2
1.3
—
—
—
0
0
9
25
3.61
2.57
1.1
1.2
—
—
—
0
0
109
805
1.37
2.54
3.2
3.3
24.78
25.26
mmol/l
0.93
102
769
305
2575
1.21
2.50
1.6
1.8
1.45
1.47
%
0.24
275
2260
19
89
2.14
2.45
1.2
1.2
—
—
—
0
0
83
590
1.42
2.43
1.4
1.5
264.97
281.79
ug/g
0.39
45
339
53
345
1.55
2.39
2.3
3.2
455.29
1730.11
u/ml
—
7
27
77
543
1.43
2.36
1.1
1.1
6.01
5.53
eliau/ml
—
9
66
97
713
1.38
2.35
1.5
1.4
—
—
—
0
0
402
3516
1.18
2.23
1.3
1.3
5.91
10.70
u/ml
1.55
162
1410
17
80
2.13
2.18
1.1
1.1
96.08
94.65
%
0.06
12
60
9
30
3.01
2.14
1.0
2.3
—
9070.00
—
0
5
16
74
2.17
2.14
1.4
1.3
—
—
—
0
0
16
74
2.17
2.14
1.4
1.3
—
—
—
0
0
5
150
0.33
2.14
1.2
1.5
—
—
—
0
0
20
102
1.97
2.10
1.5
1.3
—
—
—
0
0
22
117
1.89
2.06
1.1
1.1
1.12
1.05
ratio
0.58
17
100
47
310
1.53
2.04
1.1
1.1
125.15
115.77
%
1.16
41
285
36
223
1.62
2.03
1.5
1.4
—
—
—
0
0
8
26
3.08
2.01
1.1
1.2
—
—
—
0
0
91
682
1.35
2.00
2.2
2.2
621.96
405.82
ug/l
0.40
85
644
147
1178
1.27
1.98
4.1
3.0
132.01
129.98
g/l
0.53
140
1143
24
134
1.80
1.95
1.7
1.4
112.13
159.93
pmol/l
1.31
24
134
171
1398
1.24
1.95
1.9
2.0
—
—
—
0
0
86
1138
0.75
1.94
1.6
1.6
966.60
1014.71
mu/l
0.16
74
944
36
226
1.60
1.94
1.5
1.4
—
—
—
0
0
81
601
1.36
1.91
3.3
3.8
45.70
57.44
mg/l
0.43
69
511
36
227
1.60
1.91
1.5
1.4
—
—
—
0
0
13
58
2.25
1.91
1.2
1.2
17.61
16.32
umol/l
0.40
13
51
26
152
1.72
1.83
1.1
1.1
—
—
—
0
0
5
12
4.17
1.82
1.0
1.2
—
—
—
0
0
15
73
2.06
1.80
1.0
1.0
—
—
—
0
0
9
35
2.58
1.80
1.1
1.1
123.00
96.09
%
—
9
35
13
60
2.17
1.77
1.4
1.3
—
—
—
0
0
238
2032
1.19
1.77
8.1
6.7
—
—
—
0
0
62
446
1.40
1.77
2.6
2.3
133.12
130.66
g/l
0.37
49
361
80
601
1.34
1.76
3.3
3.8
34.30
66.93
mg/l
0.89
69
512
19
102
1.87
1.76
1.5
1.5
—
1269855.44
—
0
9
200
1683
1.21
1.74
2.0
2.1
—
—
—
0
0
6
18
3.34
1.74
1.3
1.1
—
—
—
0
0
6
18
3.34
1.74
1.2
1.2
—
—
—
0
0
21
117
1.80
1.74
1.9
2.4
7.21
8.49
mmol/l
1.12
21
117
39
257
1.53
1.74
1.2
1.7
—
—
—
0
0
115
911
1.28
1.73
3.9
3.9
45.26
48.49
%
0.68
110
891
20
110
1.83
1.73
1.4
2.9
716.45
936.50
u/ml
0.41
20
110
7
24
2.92
1.72
9.1
11.3
5.00
6.00
mmol/l
—
7
24
26
156
1.67
1.69
1.1
1.1
—
—
—
0
0
424
3808
1.14
1.65
1.4
1.3
21.28
29.62
iu/ml
1.56
116
1145
171
1428
1.21
1.63
1.3
1.3
112.99
230.79
u/ml
3.71
166
1326
70
524
1.35
1.60
1.4
1.6
—
—
—
0
0
703
6523
1.12
1.60
3.3
3.5
7.91
7.81
mmol/l
0.21
607
5588
27
167
1.62
1.58
1.1
1.1
—
—
—
0
0
59
796
0.73
1.57
1.1
1.1
0.65
0.65
ratio
—
10
87
26
160
1.63
1.56
1.1
1.1
—
—
—
0
0
26
160
1.63
1.56
1.1
1.1
—
—
—
0
0
36
240
1.51
1.55
1.2
1.2
—
—
—
0
0
106
846
1.27
1.53
1.5
1.9
1.37
1.50
g/l
0.70
93
743
74
563
1.33
1.53
1.3
1.3
—
—
—
0
0
25
153
1.64
1.53
1.2
1.6
—
—
—
0
0
94
740
1.28
1.52
1.3
1.3
241.95
221.98
miu/ml
0.20
39
358
64
848
0.75
1.51
1.2
1.1
1.55
1.53
g/l
0.22
64
848
33
217
1.53
1.51
1.5
1.4
—
—
—
0
0
38
258
1.48
1.51
1.2
1.7
—
—
—
0
0
71
539
1.33
1.50
1.5
1.6
—
—
—
0
0
284
2500
1.16
1.48
2.2
2.1
—
—
—
0
0
53
385
1.39
1.48
15.4
8.3
10.74
11.34
mmol/l
0.99
43
344
27
171
1.59
1.46
1.3
1.1
124.33
108.14
pmol/l
0.93
27
171
53
386
1.38
1.46
15.4
8.3
106.19
105.26
mmol/l
0.68
43
345
59
438
1.36
1.45
1.4
1.6
—
—
—
0
0
20
117
1.72
1.45
6.5
6.9
5.64
176.86
ug/l
0.61
11
74
17
95
1.80
1.43
2.2
3.3
141.89
136.91
umol/l
—
9
55
309
2749
1.14
1.40
2.2
2.2
—
—
—
0
0
251
2200
1.16
1.40
5.1
4.8
31.09
32.01
%
0.68
193
1518
95
759
1.26
1.39
1.5
1.7
11.60
16.03
u/ml
0.36
13
189
29
190
1.53
1.37
1.1
1.1
—
—
—
0
0
50
366
1.37
1.35
1.2
1.3
—
—
—
0
0
50
366
1.37
1.35
1.2
1.3
—
—
—
0
0
48
349
1.38
1.35
1.5
1.7
—
—
—
0
0
30
199
1.51
1.35
9.3
5.8
8.52
7.20
mmol/l
0.39
24
163
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
76
593
1.29
1.34
3.1
3.3
0.39
0.35
iu/ml
0.37
47
324
32
216
1.49
1.33
1.5
1.4
—
—
—
0
0
32
216
1.49
1.33
1.5
1.4
—
—
—
0
0
69
535
1.30
1.29
3.4
3.6
7.33
3.93
ratio
0.28
38
302
64
492
1.31
1.27
1.2
1.2
18.14
50.24
u/ml
—
7
48
29
195
1.49
1.24
5.0
4.9
327.42
85.45
u/ml
—
8
60
58
752
0.76
1.22
1.5
1.4
—
—
—
0
0
13
71
1.84
1.19
1.4
1.3
—
—
—
0
0
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
91
740
1.24
1.18
2.3
2.0
2.08
1.65
ug/l
0.21
78
657
24
157
1.53
1.17
1.3
1.2
—
88.20
—
0
5
22
142
1.55
1.14
1.2
1.1
—
—
—
0
0
28
191
1.47
1.14
1.7
1.7
—
—
—
0
0
44
327
1.35
1.12
1.1
1.1
—
—
—
0
0
114
955
1.20
1.12
1.6
1.7
0.29
0.31
mg/l
0.13
47
461
27
184
1.47
1.11
1.1
1.1
309.56
287.05
mg/l
0.80
27
167
7
31
2.26
1.10
1.1
1.2
—
—
—
0
0
16
96
1.67
1.10
1.1
1.1
—
—
—
0
0
18
113
1.60
1.05
1.0
1.2
—
—
—
0
0
18
113
1.60
1.05
1.1
1.3
129.61
141.29
nmol/l
0.75
18
113
20
300
0.66
1.03
5.2
4.1
37.10
28.65
u/ml
0.17
20
294
21
138
1.53
1.03
1.2
1.2
—
—
—
0
0
30
213
1.41
1.02
1.8
1.8
16.74
21.19
ug/l
1.08
30
208
74
601
1.24
1.00
1.3
1.3
1.83
2.35
u/ml
—
6
54
17
107
1.59
0.99
3.5
3.7
0.76
0.86
index
0.27
17
107
37
275
1.35
0.97
3.6
2.8
244.50
63.13
u/ml
0.34
37
269
7
36
1.95
0.97
1.0
1.1
—
—
—
0
0
74
604
1.23
0.97
1.2
1.3
10.57
10.36
u/ml
—
9
89
6
118
0.51
0.94
1.5
1.3
—
—
—
0
0
155
1363
1.15
0.89
3.0
2.9
120.48
190.98
ng/l
2.97
141
1234
19
127
1.50
0.88
1.3
1.2
—
—
—
0
0
29
211
1.38
0.88
1.8
2.2
12.88
23.42
mg/l
—
8
81
54
431
1.26
0.88
1.0
1.1
4.24
5.40
u/ml
0.17
27
241
51
406
1.26
0.85
1.4
1.5
141.27
156.74
au/ml
0.48
11
115
15
96
1.57
0.84
1.1
1.1
—
—
—
0
0
20
137
1.46
0.84
1.3
1.2
—
—
—
0
0
10
57
1.76
0.83
1.1
1.3
—
—
—
0
0
210
2322
0.89
0.82
1.8
1.9
3.49
3.49
ratio
0.03
157
1791
44
346
1.28
0.82
1.1
1.2
8.57
1733.93
iu/ml
0.54
12
77
6
32
1.88
0.81
1.0
2.3
—
—
—
0
0
34
258
1.32
0.81
1.3
1.1
—
—
—
0
0
48
597
0.80
0.80
1.5
1.5
1.06
1.14
ratio
0.22
27
365
48
597
0.80
0.80
1.5
1.5
0.89
0.95
ratio
0.61
27
365
48
597
0.80
0.80
1.5
1.5
0.98
1.18
ratio
1.47
27
365
6
33
1.82
0.79
1.0
1.3
—
—
—
0
0
0
26
0.00
0.78
0.0
2.8
—
0.77
—
0
26
12
74
1.63
0.78
1.1
1.5
111.60
90.61
%
—
5
41
28
208
1.35
0.77
1.7
1.6
—
—
—
0
0
27
200
1.35
0.76
1.1
1.3
—
—
—
0
0
42
333
1.27
0.75
1.5
1.2
1.88
4.12
u/ml
1.28
16
121
39
492
0.79
0.74
1.4
1.2
—
—
—
0
0
60
497
1.21
0.73
1.3
1.3
—
10.92
—
0
5
5
25
2.00
0.72
1.0
2.5
—
—
—
0
0
42
335
1.26
0.72
1.0
1.1
2.18
5.06
u/ml
1.55
13
148
48
588
0.81
0.72
1.5
1.5
—
—
—
0
0
51
417
1.23
0.71
1.0
1.1
1.77
1.49
u/ml
0.07
22
182
40
318
1.26
0.70
1.0
1.1
0.09
0.26
u/ml
—
8
107
123
1089
1.14
0.69
1.0
1.1
—
—
—
0
0
157
1742
0.89
0.68
1.6
1.7
3.42
3.47
mmol/l
0.18
104
1216
66
557
1.19
0.68
1.1
1.1
3.69
3.80
—
9
79
33
418
0.79
0.67
1.2
1.5
59.94
59.44
ug/l
0.03
33
418
168
1520
1.11
0.66
2.4
2.5
0.24
0.46
e6/l
1.35
159
1450
60
504
1.20
0.65
1.5
1.4
—
—
—
0
0
101
886
1.15
0.65
1.8
1.9
9.12
7.96
iu/ml
0.14
21
215
44
537
0.82
0.65
1.3
1.6
—
—
—
0
0
7
44
1.59
0.65
1.1
1.0
25.26
52.43
iu/ml
—
7
44
21
154
1.37
0.65
4.5
2.4
25.86
35.23
mg/l
0.82
14
110
20
146
1.37
0.63
1.1
1.5
—
—
—
0
0
13
87
1.50
0.63
2.2
2.5
—
—
—
0
0
160
1449
1.11
0.63
1.5
1.5
—
—
—
0
0
23
173
1.33
0.61
3.5
3.3
12.59
13.20
index
0.14
17
107
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
53
445
1.20
0.59
1.2
1.3
153.50
256.16
u/ml
4.83
28
272
40
327
1.23
0.58
1.5
1.2
11.94
4.89
u/ml
0.70
16
152
25
320
0.78
0.57
3.0
3.4
0.84
0.83
nmol/l
0.05
18
264
55
646
0.85
0.56
1.5
1.5
59.13
60.04
ug/l
0.05
49
533
631
6067
1.06
0.55
4.0
4.3
7.22
8.99
mg/mmol
0.43
386
3858
72
627
1.15
0.54
1.2
1.3
—
—
—
0
0
415
3950
1.06
0.52
1.8
1.6
—
—
—
0
0
23
179
1.29
0.51
2.4
2.5
—
—
—
0
0
48
407
1.18
0.51
2.1
1.6
—
—
—
0
0
163
1499
1.09
0.50
2.2
2.4
6.21
7.21
ug/l
0.31
138
1351
43
361
1.20
0.50
1.0
1.1
1.03
3.26
u/ml
2.46
15
182
9
65
1.39
0.50
2.9
2.8
27.44
30.81
umol/l
—
9
44
22
171
1.29
0.49
1.2
1.5
0.87
1.10
promille
0.39
16
139
19
145
1.31
0.48
1.1
1.9
—
—
—
0
0
28
229
1.23
0.44
1.1
1.1
—
—
—
0
0
13
174
0.75
0.43
1.5
1.4
63202.43
95265.69
e6/l
—
7
97
11
150
0.73
0.41
1.0
1.5
—
—
—
0
0
21
168
1.25
0.40
1.0
1.1
9.38
16.60
u/ml
—
6
74
42
486
0.86
0.40
1.6
1.7
—
—
—
0
0
9
66
1.37
0.38
2.3
1.4
11.65
8.94
ug/l
—
9
66
83
753
1.11
0.37
1.4
1.5
—
—
—
0
0
13
99
1.32
0.35
1.0
1.7
0.87
4.32
u/field
—
8
77
26
308
0.84
0.34
1.2
1.2
—
—
—
0
0
11
82
1.34
0.34
3.1
4.4
—
—
—
0
0
17
136
1.25
0.33
1.9
1.4
88.53
79.25
umol/l
0.50
17
136
6
46
1.31
0.33
1.2
1.2
—
—
—
0
0
110
1020
1.08
0.33
2.7
3.1
307.03
69.98
u/ml
0.40
103
989
10
74
1.35
0.32
1.9
1.8
40.81
40.79
g/l
—
10
74
62
685
0.90
0.31
3.7
3.5
363.96
2305.07
u/ml
0.74
49
593
7
55
1.27
0.30
6.3
2.6
1.48
2.20
ratio
—
7
49
75
688
1.09
0.29
1.5
1.6
0.13
0.13
iu/ml
0.01
11
107
7
56
1.25
0.29
3.1
2.6
8.74
10.20
kpa
—
7
56
7
56
1.25
0.29
3.1
2.6
5.00
4.85
kpa
—
7
56
46
412
1.12
0.28
1.0
1.1
0.30
1.58
u/ml
4.11
18
210
17
205
0.83
0.28
1.4
1.4
1915.25
1883.65
e6/l
0.02
12
143
9
121
0.74
0.27
1.2
1.1
1241.78
1502.73
miu/ml
—
9
121
28
243
1.15
0.27
1.2
1.2
—
—
—
0
0
34
300
1.14
0.26
1.1
1.1
1.50
2.49
eliau/ml
0.82
19
134
462
4498
1.03
0.25
3.8
3.9
1.02
1.35
kg/l
0.50
311
3002
15
124
1.21
0.24
1.2
1.4
11.40
13.63
u/l
1.37
15
118
11
88
1.25
0.22
1.0
1.1
174.46
204.79
iu/ml
0.24
11
88
75
803
0.93
0.22
1.7
1.7
3.92
4.92
mg/l
0.48
59
586
0
11
0.00
0.21
0.0
1.6
—
11.80
—
0
5
0
12
0.00
0.21
0.0
2.6
—
2.99
—
0
12
8
105
0.76
0.21
1.1
1.5
34.50
28.67
umol/l
—
8
97
8
105
0.76
0.21
1.4
1.2
14.00
8.61
mm/h
—
8
105
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
13
0.00
0.21
0.0
1.2
—
4782.71
—
0
7
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
14
117
1.20
0.20
1.2
1.6
—
—
—
0
0
62
665
0.93
0.20
1.5
1.5
—
—
—
0
0
24
212
1.13
0.19
1.1
1.4
1.59
1.44
nmol/l
0.26
19
193
21
184
1.14
0.19
1.2
1.3
0.25
0.71
u/ml
0.94
12
97
53
492
1.08
0.18
1.1
1.1
0.91
2.74
u/ml
2.11
25
262
50
463
1.08
0.18
1.2
1.5
—
—
—
0
0
37
339
1.09
0.17
1.6
1.7
—
—
—
0
0
95
905
1.05
0.16
2.8
3.2
1.02
1.02
ratio
0.13
83
835
12
101
1.19
0.16
1.0
1.9
—
—
—
0
0
12
101
1.19
0.16
1.0
1.9
—
—
—
0
0
15
171
0.88
0.14
1.0
1.8
—
—
—
0
0
38
409
0.93
0.14
2.7
2.4
172.28
121.55
ug/min
0.25
16
250
13
112
1.16
0.14
1.2
1.6
—
—
—
0
0
52
489
1.06
0.14
1.9
1.7
15833.34
11961.01
e6/l
0.27
38
349
14
160
0.87
0.14
1.3
1.7
—
—
—
0
0
16
141
1.14
0.14
1.4
2.1
0.88
1.86
u/field
—
8
86
19
170
1.12
0.13
1.8
1.4
—
—
—
0
0
19
170
1.12
0.13
1.8
1.4
—
—
—
0
0
19
170
1.12
0.13
1.8
1.4
—
—
—
0
0
36
387
0.93
0.13
1.1
1.5
—
—
—
0
0
34
315
1.08
0.13
1.1
1.5
—
—
—
0
0
13
113
1.15
0.13
2.2
1.9
88.78
107.65
ng/l
0.41
13
113
67
638
1.05
0.13
2.4
2.8
—
—
—
0
0
11
96
1.15
0.10
2.4
1.5
—
—
—
0
0
11
96
1.15
0.10
2.4
1.5
—
—
—
0
0
11
96
1.15
0.10
2.4
1.5
—
—
—
0
0
11
96
1.15
0.10
2.4
1.5
—
—
—
0
0
98
1010
0.97
0.09
1.3
1.4
—
—
—
0
0
32
302
1.06
0.08
1.6
1.5
—
—
—
0
0
7
64
1.09
0.08
3.6
2.6
0.62
0.62
mmol/l
—
7
64
7
68
1.03
0.07
2.3
3.5
—
90.18
—
0
17
12
133
0.90
0.07
2.2
2.3
550.57
633.10
ml
—
7
84
6
72
0.83
0.07
1.0
1.7
0.52
0.46
e9/l
—
6
72
8
75
1.07
0.07
3.0
1.6
—
—
—
0
0
8
75
1.07
0.07
2.9
1.6
—
—
—
0
0
8
75
1.07
0.07
2.9
1.6
—
—
—
0
0
12
108
1.11
0.07
1.2
1.5
22.78
33.01
nmol/l
0.84
12
89
7
83
0.84
0.07
1.0
1.1
—
—
—
0
0
9
85
1.06
0.07
1.4
3.0
14.11
117.98
ug/l
—
9
71
15
163
0.92
0.07
1.3
1.3
321.00
370.64
u/l
0.14
15
157
17
183
0.93
0.06
4.1
3.9
—
—
—
0
0
36
376
0.96
0.06
1.0
1.1
8.39
20.08
au/ml
—
10
107
180
1826
0.98
0.06
4.0
4.3
82.07
22.57
ug/l
0.57
136
1477
28
293
0.96
0.05
2.9
2.1
10.75
4.99
umol/l
0.60
23
211
11
120
0.92
0.05
1.3
1.1
—
—
—
0
0
20
189
1.06
0.04
1.1
1.0
—
—
—
0
0
330
3325
0.99
0.04
1.5
1.5
—
—
—
0
0
1595
15979
0.99
0.04
25.2
19.5
332.46
332.62
g/l
0.29
1585
15896
39
401
0.97
0.03
1.2
1.5
—
—
—
0
0
54
549
0.98
0.02
1.2
1.2
—
—
—
0
0
12
113
1.06
0.01
1.3
1.3
—
885.56
—
0
9
38
373
1.02
0.01
3.2
3.6
28.57
26.44
mg/l
0.17
26
257
13
129
1.01
0.00
1.2
1.6
—
—
—
0
0
30
305
0.98
0.00
1.1
1.1
3.22
2.17
—
5
52
38
375
1.01
0.00
1.2
1.6
—
—
—
0
0
15
152
0.99
0.00
1.2
1.1
10.82
9.84
iu/ml
—
6
43
55
547
1.01
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
7
74
0.95
-0.00
1.1
2.6
—
40734.00
—
0
11
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
26.50
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
84
0.95
-0.00
2.4
3.5
2.63
1.32
%
—
8
84
0
7
0.00
-0.00
0.0
1.0
—
1296.71
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_PITUITARY_CRANIPHAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PITUITARY_CRANIPHAR | 1.615 [1.4, 1.86] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.242 |
During the follow-up period (1.1.1998 — 31.12.2019), 512 out of 4286 females with CD2_BENIGN_PITUITARY_CRANIPHAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PITUITARY_CRANIPHAR | 1.312 [1.15, 1.5] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 610 out of 3161 males with CD2_BENIGN_PITUITARY_CRANIPHAR died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_PITUITARY_CRANIPHAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.146% | 0.276% |
| 5 | 0.905% | 1.452% |
| 10 | 2.203% | 3.392% |
| 15 | 4.48% | 6.597% |
| 20 | 7.905% | 11.263% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_PITUITARY_CRANIPHAR – Benign neoplasm: Pituitary gland, craniopharyngeal duct
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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