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Erythema nodosum

DOID EFO Endpoint Browser PheWeb

L12_ERYTHEMANODOSUM

erythema infectiosum: usually a benign childhood condition characterized by a classic slapped-cheek appearance (see the image below) and lacy exanthem.It results from infection with human parvovirus (PV) B19, an erythrovirus.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519870

1. Apply sex-specific rule

None

519870

2. Check conditions

None

519870

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L52
  • Hospital discharge: ICD-9 — 6952
  • Hospital discharge: ICD-8 — 69520
  • Cause of death: ICD-10 — L52
  • Cause of death: ICD-9 — 6952
  • Cause of death: ICD-8 — 69520

2 out of 7 registries used, show all original rules.

1182

4. Check minimum number of events

None

1182

5. Include endpoints

None

1182

6. Filter based on genotype QC (FinnGen only)

1140

Control definitions (FinnGen only)

Control exclude
L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L50-L54
Name in latin
Erythema nodosum

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9004 6843 2116
Only index persons 7799 5941 1858
Unadjusted period prevalence (%)
Whole population 0.16 0.20 0.06
Only index persons 0.18 0.22 0.07
Median age at first event (years)
Whole population 40.55 41.91 36.01
Only index persons 37.81 38.86 34.46

-FinnGen-

Key figures

All Female Male
Number of individuals 1140 903 237
Unadjusted period prevalence (%) 0.28 0.32 0.11
Median age at first event (years) 39.33 38.87 41.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1182
Matched controls
11820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L52
ICD-10 Finland
Erythema nodosum
1133.5
307.7
716
16
69520
ICD-8 Finland
Erythematous condition, Erythema nodosum
+∞
293.3
269
*
6952A
ICD-9 Finland
Erythematous conditions, Erythema nodosum[ERYTHEMA NODOSUM ACUTUM]
+∞
111.2
105
*
M79.3
ICD-10 Finland
Panniculitis, unspecified
56.5
95.2
54
10
M148, L529,
ICD-10 Finland
+∞
90.8
86
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.5
77.9
215
551
L04AX01
ATC
azathioprine; systemic
6.2
67.8
122
214
D86.0
ICD-10 Finland
Sarcoidosis of lung
12.9
66.3
65
53
H02AB06
ATC
prednisolone; systemic
2.8
65.7
716
4150
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
17.3
63.7
53
32
A46
ICD-10 Finland
Erysipelas
3.2
51.8
248
909
M14.8*L52
ICD-10 Finland
Arthropathy in erythema: nodosum
+∞
43.0
41
*
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
11.4
40.8
43
39
L529, ,
ICD-10 Finland
+∞
39.8
38
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.4
38.7
102
248
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
34.7
618
4028
A07EC02
ATC
mesalazine; oral, rectal
3.7
31.1
105
305
13597
ICD-8 Finland
Sarcoidosis, Suspecta
42.3
30.1
37
9
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
11.8
29.2
30
26
K50.8
ICD-10 Finland
Other Crohn disease
6.8
29.1
46
70
132
Kela drug reimbursment
Sarcoidosis
11.0
28.8
31
29
R50.9
ICD-10 Finland
Fever, unspecified
2.4
27.4
230
1095
H02AB07
ATC
prednisone; oral
2.4
25.3
201
931
J01FF01
ATC
clindamycin; systemic
2.0
23.7
359
2135
R60.0
ICD-10 Finland
Localized oedema
2.4
23.4
186
860
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
8.3
22.7
30
37
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.1
22.7
63
159
K51.5
ICD-10 Finland
Left sided colitis
4.4
22.2
56
131
K50.1
ICD-10 Finland
Crohn disease of large intestine
7.2
22.1
33
47
A02BC02
ATC
pantoprazole; systemic
1.9
21.7
845
6713
TGC00
NOMESCO Finland
Bronchial lavation
4.7
21.6
50
109
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
21.6
172
795
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
21.4
298
1714
J01MA02
ATC
ciprofloxacin; systemic
1.8
21.2
463
3078
M13.9
ICD-10 Finland
Arthritis, unspecified
2.7
21.0
121
480
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
20.2
181
879
UJF32
NOMESCO Finland
Coloscopy
1.9
19.7
328
1995
K50.9
ICD-10 Finland
Crohn disease, unspecified
5.2
19.4
40
79
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
19.3
142
633
L04AA06
ATC
mycophenolic acid; systemic
5.3
19.0
38
73
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.1
18.6
80
270
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
18.4
152
712
D07AC01
ATC
betamethasone; topical
1.8
18.4
449
3055
SPAT1255
SPAT
Intravenous administration of medicine
2.8
18.3
93
345
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
18.2
447
3044
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
3.3
17.9
70
223
E0000UV, ,
ATC
1.7
17.8
531
3811
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
17.7
364
2352
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
7.0
17.0
26
38
TQW80
NOMESCO Finland
Local dermatologic skincare
4.2
16.7
45
111
C03CA01
ATC
furosemide; systemic
1.8
16.6
332
2121
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
16.0
103
431
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.5
15.9
56
167
L04AX03
ATC
methotrexate; systemic
2.2
15.6
141
684
ZX120
NOMESCO Finland
Intravenous
2.3
15.6
130
610
K51.8
ICD-10 Finland
Other ulcerative colitis
5.0
15.5
33
67
M04AA01
ATC
allopurinol; systemic
2.2
15.1
135
652
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
4.3
14.9
39
94
M14.8
ICD-10 Finland
Arthropathies in other specified diseases classified elsewhere
81.1
14.6
16
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.4
14.3
108
485
H02AB04
ATC
methylprednisolone; systemic
2.0
14.2
180
989
J01DA01
ATC
[U] cefalexin
1.6
14.0
735
5948
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
14.0
264
1646
A07EA06
ATC
budesonide; oral, local oral
3.0
14.0
62
213
R60.9
ICD-10 Finland
Oedema, unspecified
2.6
13.9
84
340
127
Kela drug reimbursment
Transplant complication
5.6
13.9
26
47
1350A
ICD-9 Finland
Sarcoidosis[SARCOIDOSIS]
18.5
13.4
20
11
P01BA02
ATC
hydroxychloroquine; oral
2.2
13.4
120
580
A07EA02
ATC
hydrocortisone; rectal
4.1
13.2
36
90
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
13.0
71
274
H02AB09
ATC
hydrocortisone; systemic
3.6
12.9
42
119
SPAT1263
SPAT
Sampling
1.6
12.9
490
3650
M14.8*D86.8
ICD-10 Finland
Arthropathy in sarcoidosis
70.6
12.6
14
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
12.3
100
464
J01MA12
ATC
levofloxacin; systemic
1.8
12.1
205
1233
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
12.1
73
296
J01DB01
ATC
cefalexin; oral
1.7
11.7
970
8575
L04AA01
ATC
[U] ciclosporin
5.6
11.7
22
40
K50.0
ICD-10 Finland
Crohn disease of small intestine
4.0
11.5
32
81
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
11.0
229
1459
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.5
11.0
69
285
S97
ICPC
Chronic ulcer skin
2.3
10.8
80
357
L04AB04
ATC
adalimumab; parenteral
3.4
10.7
39
119
D86.3
ICD-10 Finland
Sarcoidosis of skin
18.0
10.7
16
9
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
10.5
140
780
L17
ICPC
Foot/toe symptom/complaint
1.6
10.4
369
2674
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.7
10.3
55
210
13599
ICD-8 Finland
Sarcoidosis, Unspecified
13.2
10.2
17
13
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.7
10.1
32
89
D07AD01
ATC
clobetasol; topical
1.7
10.0
200
1258
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
10.0
269
1828
S01
ICPC
Pain/tenderness of skin
2.5
9.8
63
263
M30.0
ICD-10 Finland
Polyarteritis nodosa
20.2
9.8
14
7
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.0
9.8
105
543
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
9.7
70
309
S18
ICPC
Laceration/cut
1.5
9.7
531
4203
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.6
436
3320
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.2
9.6
83
395
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
9.2
9.5
19
21
A07EC01
ATC
sulfasalazine; oral, rectal
2.0
9.3
100
517
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
9.3
139
803
C03DA01
ATC
spironolactone; oral
1.8
9.3
135
774
XG410
NOMESCO Finland
Flow-volume spirometry
2.6
9.2
51
199
SPAT1262
SPAT
Handing over of treatment supplies
1.7
9.2
183
1150
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.1
310
2216
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
3.7
9.0
28
77
J01AA02
ATC
doxycycline; systemic
1.5
9.0
884
7795
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.1
9.0
37
122
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
9.0
74
345
R03AC02
ATC
salbutamol; inhalant
1.5
9.0
655
5445
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
8.9
60
257
J01DA09
ATC
[U] cefadroxil
1.5
8.9
304
2176
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
4.7
8.8
20
43
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
8.8
267
1859
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
3.6
8.7
28
79
L04AD01
ATC
ciclosporin; systemic
3.8
8.5
25
66
L50.9
ICD-10 Finland
Urticaria, unspecified
3.5
8.5
29
85
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.4
8.5
30
90
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
8.5
199
1302
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.5
458
3587
WZC00, ,
SPAT
1.7
8.4
177
1126
L95.8
ICD-10 Finland
Other vasculitis limited to skin
12.9
8.4
14
11
B01AB05
ATC
enoxaparin; parenteral
1.5
8.2
349
2605
L01BB02
ATC
mercaptopurine; oral
4.4
8.2
20
46
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.0
8.0
85
438
M79.6
ICD-10 Finland
Pain in limb
1.4
8.0
518
4184
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
7.9
146
896
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.9
475
3780
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.7
7.8
136
821
D07AC13
ATC
mometasone; topical
1.5
7.8
318
2351
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.7
7.8
41
156
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
7.7
59
267
SPAT1260
SPAT
Consultation of another employee
1.6
7.7
192
1273
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
7.7
45
180
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.5
478
3833
D94
ICPC
Chronic enteritis/ulcerative colitis
7.2
7.5
17
24
L01BA01
ATC
methotrexate; systemic
2.5
7.5
46
189
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
7.4
224
1552
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
7.4
136
834
S29
ICPC
Skin symptom/complaint other
1.5
7.4
232
1623
J01FA06
ATC
roxithromycin; oral
1.4
7.4
445
3534
6952C
ICD-9 Finland
Erythematous conditions, Erythema nodosum[VASCULITIS NODULARIS,ERYTHEMA INDURATUM NONTUBERCUL]
+∞
7.3
7
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.3
7.3
52
229
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.2
136
839
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
15.9
7.2
11
7
A08
ICPC
Swelling
2.0
7.1
71
358
L50.8
ICD-10 Finland
Other urticaria
8.0
7.1
15
19
K51
ICD-10 Finland
Ulcerative colitis
4.1
7.1
19
47
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.5
7.1
44
182
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
7.0
253
1821
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
3.4
7.0
24
71
T90
ICPC
Diabetes non-insulin dependent
1.5
7.0
242
1728
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
6.9
144
912
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.4
6.9
44
184
D86
ICD-10 Finland
Sarcoidosis
13.9
6.9
11
8
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.4
6.9
24
72
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
6.8
108
636
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.3
6.8
48
211
XW000
NOMESCO Finland
Bone marrow biopsy
2.4
6.8
44
186
03992
ICD-8 Finland
Other bacterial diseases, Infectio Yersinia (Pasteurella) enterocolitica
40.3
6.8
8
*
R05
ICD-10 Finland
Cough
1.5
6.7
249
1800
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
6.7
105
616
J02AC01
ATC
fluconazole; systemic
1.4
6.7
480
3910
S76
ICPC
Skin infection other
2.1
6.6
63
312
E000001, ,
ATC
1.5
6.6
216
1520
J04BA02
ATC
dapsone; oral
7.9
6.6
14
18
XQ848
NOMESCO Finland
Dermatological photography
2.6
6.6
36
140
M25.5
ICD-10 Finland
Pain in joint
1.4
6.5
392
3096
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
6.5
60
294
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
6.5
236
1699
B01AB10
ATC
tinzaparin; parenteral
1.7
6.5
126
785
L04AD02
ATC
tacrolimus; systemic
5.7
6.5
17
30
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
4.0
6.5
18
46
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.0
6.5
18
46
A18.4
ICD-10 Finland
Tuberculosis of skin and subcutaneous tissue
70.2
6.4
7
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.5
6.4
38
154
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
6.3
133
845
H15.1
ICD-10 Finland
Episcleritis
3.2
6.3
24
76
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.5
6.2
39
162
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
6.2
43
187
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
7.1
6.2
14
20
R06AE07
ATC
cetirizine; oral
1.4
6.2
498
4114
SPAT1229
SPAT
Assessment of need for aid
1.9
6.2
78
427
M05BA04
ATC
alendronic acid; oral
1.7
6.2
103
615
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
6.2
238
1733
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
6.1
121
758
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
6.1
105
634
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.4
6.0
38
159

TimeCodeWAS

↥

TODO / Current known limitations:

  • Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
  • Legend / how to read the glyphs.
  • Proper column names.
  • Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
  • Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
  • Download CSV not working.
  • No filters and sorters.
  • Limited amount of endpoints with TimeCodeWAS data.
  • Cross-links to Risteys lab test pages for lab test codes.
OMOP Concept
ln(OR) -5y
ln(OR) -1y
ln(OR) -1m
ln(OR) d0
ln(OR) +1m
ln(OR) +1y
ln(OR) +5y
MCC -5y
MCC -1y
MCC -1m
MCC d0
MCC +1m
MCC +1y
MCC +5y
Arthropathies in other specified diseases classified elsewhere and NA
M14.8*L52.9 (2000504082)
Erythema nodosum
L52 (45552985)
Panniculitis, unspecified
M79.3 (45577357)
Arthropathy in erythema: nodosum
M14.8*L52 (2000503036)
Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
31374-2 (3007080)
Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
5159-9 (3007844)
Lysozyme [Mass/volume] in Serum or Plasma
2589-0 (3012110)
Body height measure
50373000 (4177340)
Body mass index
60621009 (4245997)
Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
89640-7 (1175715)
Erythematous conditions, Erythema nodosum[ERYTHEMA NODOSUM ACUTUM]
6952A (2000405502)
Biopsy of skin and subcutaneous tissue
TQX10 (2001310152)
SMOKING - SMOKE2: no - SMOKE3: former - SMOKE5: Unspecified
SMOKING-2-2-0 (2002330110)
SMOKING - SMOKE2: no - SMOKE3: never - SMOKE5: Unspecified
SMOKING-2-3-0 (2002330113)
Proteinase 3 Ab [Units/volume] in Serum
6968-2 (3009445)
Calcium [Moles/time] in 24 hour Urine
14637-3 (3010838)
Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
2742-5 (3034780)
Chlamydophila sp Ab [Presence] in Serum
46179-8 (3047007)
Epstein Barr virus Ab [Presence] in Serum
49178-7 (3048929)
Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
88518-6 (36304997)
Sarcoidosis of lung
D86.0 (45576422)
Ulcerative colitis, unspecified
K51.9 (45605941)
Erythematous condition, Erythema nodosum
69520 (2000304351)
Joint ultrasound examination not elsewhere classified
NK4XE (2001308469)
Medical doctor
Z2221 (2001311556)
Sarcoidosis
132 (2001600129)
SMOKING - SMOKE2: no - SMOKE3: never - SMOKE5: never
SMOKING-2-3-5 (2002330114)
SMOKING - SMOKE2: yes - SMOKE3: current - SMOKE5: Unspecified
SMOKING-1-1-0 (2002330116)
Complement C3 [Mass/volume] in Serum or Plasma
4485-9 (3000620)
Epithelial cells [#/volume] in Urine
30383-4 (3000850)
Neutrophil cytoplasmic Ab [Units/volume] in Serum
5128-4 (3001334)
Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
14278-6 (3003284)
Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
14277-8 (3004383)
Mycobacterium sp identified in Specimen by Organism specific culture
543-9 (3005702)
Complement C4 [Mass/volume] in Serum or Plasma
4498-2 (3017766)
Hepatitis B virus core Ab [Presence] in Serum
16933-4 (3021879)
Bacteria identified in Blood by Culture
600-7 (3023368)
DNA double strand Ab [Units/volume] in Serum
5130-0 (3023420)
Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
546-2 (3024135)
Osmolality of Urine
2695-5 (3026782)
Epithelial cells.squamous [#/volume] in Urine by Automated count
51486-9 (3029879)
Epithelial cells.non-squamous [#/volume] in Urine by Automated count
51485-1 (3030306)
Casts [#/volume] in Urine by Automated count
51483-6 (3030467)
Staphylolysin Ab [Units/volume] in Serum
5366-0 (3035947)
Salmonella sp Ab [Titer] in Serum
22527-6 (3036071)
Nuclear Ab [Titer] in Serum
29953-7 (3037522)
Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
40982-1 (3038288)
Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
40987-0 (3043924)
Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
34487-9 (3044938)
Calprotectin [Mass/mass] in Stool
38445-3 (3048689)
Myeloperoxidase IgG Ab [Units/volume] in Serum
48404-8 (3049804)
Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
48065-7 (3051714)
Bacteria [Presence] in Urine
87829-8 (36304419)
Clinical & Laboratory Dermatological Immunology Physician
207NI0002X (38003841)
Infectious Disease
44 (38004484)
Hematology
82 (38004501)
Skin Pathology biopsy report
65754-4 (40768443)
Other Crohn disease
K50.8 (45533599)
Arthritis, unspecified
M13.9 (45567463)
Dermatitis, unspecified
L30.9 (45572271)
Fever, unspecified
R50.9 (45582716)
Office Visit
OMOP4822458 (581477)
Internal Medicine
11 (38004456)
Emergency Room Visit
ER (9203)
azathioprine; oral, parenteral
L04AX01 (21603927)
Neutrophils [#/volume] in Blood by Automated count
751-8 (3013650)
Metamyelocytes/Leukocytes in Blood
28541-1 (3002179)
Inpatient Hospital
21 (8717)
Rheumatology
66 (38004491)
Myelocytes/Leukocytes in Blood
26498-6 (3017181)
prednisolone
A07EA01 (21600653)
prednisolone; oral, parenteral
H02AB06 (21602734)
C reactive protein [Mass/volume] in Serum or Plasma
1988-5 (3020460)
Blasts/Leukocytes in Blood
26446-5 (3025159)
prednisone
A07EA03 (21600655)
prednisone; oral
H02AB07 (21602735)
Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
6768-6 (3035995)
Promyelocytes/Leukocytes in Blood
26524-9 (3021440)
mesalazine; oral, rectal
A07EC02 (21600664)
Normoblasts [#/volume] in Blood
715-3 (3021589)
Emergency Medicine
93 (38004510)
Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
14804-9 (3022250)
Gastroenterology
10 (38004455)
Erysipelas
A46 (45561706)
Differential panel, method unspecified - Blood
69738-3 (42870588)
CBC W Ordered Manual Differential panel - Blood
57782-5 (40760892)
Outpatient Visit
OP (9202)
Pulmonary Disease
29 (38004472)
Intravenous
ZX120 (2001311495)
Basophils [#/volume] in Blood
26444-0 (3006315)
Monocytes [#/volume] in Blood
26484-6 (3001604)
Monocytes/Leukocytes in Blood
26485-3 (3019069)
Basophils/Leukocytes in Blood
30180-4 (3022096)
Eosinophils/Leukocytes in Blood
26450-7 (3006504)
Eosinophils [#/volume] in Blood
26449-9 (3013115)
Neutrophils/Leukocytes in Blood
26511-6 (3018010)
Lymphocytes [#/volume] in Blood
26474-7 (3019198)
Cyclic citrullinated peptide Ab [Units/volume] in Serum
53027-9 (3041942)
Predominantly allergic asthma
J45.0 (45557624)
Lymphocytes/Leukocytes in Blood
26478-8 (3002030)
ciprofloxacin; oral, parenteral
J01MA02 (21603009)
Thorax X-ray examination
GD1AA (2001303617)
Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method
4537-7 (3013707)
Supplier / Service Provider
OMOP5117446 (33004)
Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M
62238-1 (40764999)
Erythrocyte [DistWidth] in Red Blood Cells
30385-9 (3002385)
Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
1742-6 (3006923)
Creatinine [Moles/volume] in Serum or Plasma
14682-9 (3020564)
Potassium [Moles/volume] in Serum or Plasma
2823-3 (3023103)
Sodium [Moles/volume] in Serum or Plasma
2951-2 (3019550)
Platelets [#/volume] in Blood
26515-7 (3007461)
cefalexin; oral
J01DB01 (21602870)
Leukocytes [#/volume] in Blood
26464-8 (3010813)
MCH [Entitic mass]
28539-5 (3035941)
Erythrocytes [#/volume] in Blood
26453-1 (3026361)
MCV [Entitic mean volume] in Red Blood Cells
30428-7 (3024731)
Hematocrit [Volume Fraction] of Blood by calculation
20570-8 (3009542)
Hemoglobin [Mass/volume] in Blood
718-7 (3000963)
MCHC [Entitic Mass/volume] in Red Blood Cells
28540-3 (3003338)
pH of Serum or Plasma
2753-2 (3018418)
Hepatitis B virus surface Ag [Presence] in Serum
5195-3 (3019284)
CBC panel - Blood by Automated count
58410-2 (40761511)
Albumin [Mass/volume] in Serum or Plasma
1751-7 (3024561)
Urinalysis microscopic panel [#/volume] - Urine by Automated count
50554-5 (3029287)
Calcium.ionized [Moles/volume] in Serum or Plasma
1995-0 (3021347)
Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
19072-8 (3016431)
betamethasone
A07EA04 (21600656)
betamethasone
C05AA05 (21601610)
betamethasone
D07AC01 (21602120)
betamethasone
S02BA07 (21605169)
Erythrocytes [#/volume] in Urine
30391-7 (3002582)
Urate [Moles/volume] in Serum or Plasma
14933-6 (3026493)
Phosphate [Moles/volume] in Serum or Plasma
14879-1 (3003458)
Laceration/cut
S18 (2002000983)
HIV 1 and 2 tests - Meaningful Use set
75622-1 (46235355)
Leukocytes [#/volume] in Urine
30405-5 (3018095)
Albumin [Presence] in Urine by Test strip
50949-7 (3029937)
Laboratory Visit
OMOP4822461 (32036)
FEV1/FVC
19926-5 (3011505)
Forced vital capacity [Volume] Respiratory system
19870-5 (3020158)
FEV1
20150-9 (3024653)
methotrexate
L01BA01 (21601423)
methotrexate; oral, parenteral
L04AX03 (21603929)
Erythrocytes [Presence] in Urine by Automated
53292-9 (3041096)
hydrocortisone
S02BA01 (21605166)
Nitrite [Presence] in Urine by Test strip
5802-4 (3021601)
Bilirubin.total [Moles/volume] in Serum or Plasma
14631-6 (3006140)
Forced vital capacity [Volume] Respiratory system --post bronchodilation
19875-4 (3001668)
FEV1 --post bronchodilation
20155-8 (3023550)
FEV1/FVC --post bronchodilation
69970-2 (42868459)
FVC percent change Respiratory system
69982-7 (42868471)
FEV1 percent change
69983-5 (42868472)
Glucose [Presence] in Urine by Test strip
25428-4 (3009261)
Rheumatoid factor [Units/volume] in Serum or Plasma
11572-5 (3021614)
Urinalysis macro (dipstick) panel - Urine
24357-6 (3037467)
Ketones [Presence] in Urine by Test strip
2514-8 (3035350)
hydrocortisone
D07AA02 (21602102)
hydrocortisone butyrate
D07AB02 (21602106)
hydrocortisone buteprate
D07AB11 (21602115)
hydrocortisone aceponate
D07AC16 (21602135)
Short blood count panel - Blood
55429-5 (40758558)
Leukocyte esterase [Presence] in Urine by Automated test strip
60026-2 (40763086)
25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
68438-1 (40771025)
hydrocortisone
A07EA02 (21600654)
hydrocortisone
C05AA01 (21601608)
Ultrasound examination of lower leg veins
PH2AE (2001309451)
IgG [Mass/volume] in Serum or Plasma
2465-3 (3005719)
oxycodone; oral, parenteral
N02AA05 (21604260)
pH of Urine
2756-5 (3015736)
Reticulocytes [#/volume] in Blood
14196-0 (3023520)
pantoprazole; oral, parenteral
A02BC02 (21600097)
phenoxymethylpenicillin; oral
J01CE02 (21602842)
benzathine phenoxymethylpenicillin; oral
J01CE10 (21602850)
Pharmacy visit
OMOP4822462 (581458)
Bacteria [#/volume] in Urine by Automated count
51480-2 (3031040)
Physiotherapy
R4110 (2001310233)
Outpatient Hospital
22 (8756)
Inpatient Visit
IP (9201)
IgM [Mass/volume] in Serum or Plasma
2472-9 (3028026)
Case Management Agency
251B00000X (38004193)
Otolaryngology
4 (38004449)
General Practice
1 (38004446)
doxycycline; oral, parenteral
J01AA02 (21602800)
Glucose [Moles/volume] in Serum or Plasma
14749-6 (3013826)
calcium (different salts in combination); oral
A12AA20 (21600872)
General Surgery
2 (38004447)
Hepatitis C virus Ab [Presence] in Serum
16128-1 (3017143)
Essential (primary) hypertension
I10 (45591453)
Spirometry for bronchospasm with prolonged evaluation after bronchodilator
113016006 (4010399)
Immunohistochemistry procedure
117617002 (4035726)
Lumbar spine X-ray examination without contrast
NA3AA (2001307026)
ibuprofen
R02AX02 (1588667)
ibuprofen; oral, parenteral, rectal
M01AE01 (21603967)
paracetamol; oral, parenteral, rectal
N02BE01 (21604344)
Ophthalmology
18 (38004463)
diclofenac; oral, parenteral, rectal
M01AB05 (21603945)
salbutamol; inhalant
R03AC02 (21603256)

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
209
268
9.26
157.46
2.9
2.3
11.98
11.97
mg/l
0.01
197
255
138
342
4.44
51.36
1.5
1.2
—
—
—
0
0
311
1557
2.35
33.70
1.5
1.3
571.67
527.04
titre
0.17
72
341
297
1492
2.32
31.69
4.3
2.4
135.20
119.98
ug/g
0.36
252
1174
747
5437
2.02
28.68
11.8
6.0
0.57
0.56
e9/l
0.93
680
4702
765
5630
2.02
28.27
12.1
6.3
0.18
0.18
e9/l
0.08
696
4933
746
5444
2.00
28.21
11.8
6.1
0.04
0.04
e9/l
0.00
678
4705
754
5556
1.99
27.32
11.9
6.1
1.89
1.91
e9/l
0.13
694
4922
99
302
3.49
27.17
2.1
1.7
0.24
0.24
g/l
0.03
94
288
101
317
3.39
26.51
1.9
1.6
1.22
1.21
g/l
0.13
96
299
532
3529
1.92
25.92
11.4
5.9
—
—
—
0
0
431
2674
1.96
25.55
5.4
4.1
—
—
—
0
0
803
6141
1.96
24.93
14.4
9.3
4.24
4.06
e9/l
1.56
739
5353
72
188
4.01
24.74
1.3
1.3
266.37
242.06
u/ml
0.28
46
110
125
464
2.89
24.64
1.3
1.2
—
—
—
0
0
76
208
3.84
24.46
1.8
2.0
4.51
5.03
mmol/24h
0.76
69
185
36
51
7.25
24.26
1.2
1.1
175.59
186.54
iu/ml
0.09
36
51
684
5013
1.87
23.62
12.3
6.2
8.50
8.63
%
0.55
652
4708
102
358
3.02
22.19
1.5
1.2
—
—
—
0
0
677
5004
1.83
22.14
12.3
6.1
2.66
2.76
%
0.53
645
4691
63
162
4.05
22.10
1.2
1.2
—
—
—
0
0
682
5055
1.83
22.07
11.8
6.0
58.74
57.08
%
2.95
658
4833
118
451
2.80
21.98
1.9
1.7
3.98
7.26
iu/ml
1.36
27
104
638
4646
1.81
21.78
7.1
4.7
35.51
36.01
g/l
1.50
609
4385
674
4996
1.81
21.62
12.4
6.2
0.67
0.69
%
0.38
641
4674
688
5135
1.81
21.53
12.2
6.1
27.10
28.26
%
1.94
660
4879
698
5234
1.81
21.48
9.6
6.7
1.22
1.22
mmol/l
0.13
608
4531
635
4662
1.78
20.66
8.3
6.1
1.21
1.22
mmol/l
0.41
599
4304
27
35
7.87
19.60
1.3
1.0
—
—
—
0
0
171
832
2.23
18.92
4.1
2.8
10.73
10.45
g/l
0.33
160
767
394
2564
1.80
18.91
3.3
2.5
327.18
328.08
umol/l
0.06
353
2274
203
1065
2.09
18.53
2.5
2.1
346.58
382.33
nmol/l
1.75
192
992
377
2440
1.80
18.32
2.1
1.7
1.14
1.08
mg/l
0.15
295
1883
463
3195
1.74
17.93
5.5
4.0
7.40
7.40
ph
0.87
349
2294
943
7977
1.90
17.29
12.8
7.8
78.27
78.15
u/l
0.04
909
7576
468
3290
1.70
16.61
4.2
3.2
83.19
81.85
e6/l
0.01
368
2491
722
5719
1.67
15.97
5.2
3.9
0.00
4.01
estimate
1.07
177
1227
215
1213
1.94
15.84
2.0
1.6
—
—
—
0
0
222
1270
1.92
15.69
1.7
1.5
—
—
—
0
0
715
5666
1.66
15.63
5.2
3.9
0.00
0.00
estimate
0.50
173
1196
349
2298
1.74
15.52
3.2
2.6
6.04
7.04
e6/l
0.74
317
2107
247
1480
1.85
15.06
3.3
2.4
19.65
22.29
%
3.04
228
1386
721
5769
1.64
14.77
5.2
4.0
0.00
0.26
estimate
0.51
175
1159
278
1737
1.79
14.73
3.4
2.4
11.56
12.98
umol/l
3.31
264
1616
39
95
4.21
14.73
1.8
1.4
—
—
—
0
0
694
5513
1.63
14.53
8.0
6.1
10.01
11.09
umol/l
3.15
674
5261
158
823
2.06
14.52
3.2
2.6
74.18
72.76
e9/l
0.14
113
591
651
5095
1.62
14.45
3.3
2.5
76.91
77.60
nmol/l
0.26
612
4636
194
1090
1.93
14.38
4.1
2.5
1.89
1.87
%
0.11
179
972
101
440
2.42
14.34
1.3
1.3
0.24
1.15
u/ml
0.79
15
29
44
121
3.74
14.10
1.2
1.2
—
—
—
0
0
836
6985
1.67
14.06
6.2
4.7
317.50
1658.61
e6/l
—
8
100
404
2826
1.65
14.06
3.9
3.1
0.27
0.42
e6/l
1.77
305
2056
519
3867
1.61
13.96
5.1
3.8
61.46
87.93
e6/l
1.01
386
2660
133
659
2.15
13.92
2.2
1.8
1.01
1.40
g/l
2.54
123
609
368
2519
1.67
13.90
8.1
4.6
—
—
—
0
0
38
97
4.01
13.50
1.7
1.4
7.32
6.90
g/l
0.16
27
73
38
97
4.01
13.50
1.7
1.4
0.36
0.36
g/l
0.03
27
73
38
97
4.01
13.50
1.7
1.4
2.70
2.84
g/l
0.17
27
71
399
2811
1.63
13.35
3.1
2.2
3.24
2.82
mg/l
2.21
352
2421
167
915
1.96
13.28
7.1
4.1
0.47
0.71
%
1.18
66
252
387
2717
1.63
13.08
3.7
3.0
—
0.00
estimate
—
0
8
152
811
2.00
13.03
3.0
3.0
67.33
67.00
g/l
0.23
143
748
80
327
2.55
13.01
1.3
1.2
2.38
2.44
u/ml
—
8
32
605
4726
1.57
12.98
17.5
11.0
0.00
0.00
e9/l
0.18
518
3893
256
1615
1.75
12.94
3.3
2.4
2.36
2.35
g/l
0.18
236
1494
134
685
2.08
12.91
2.6
2.6
—
—
—
0
0
324
2185
1.67
12.79
2.1
2.0
—
—
—
0
0
171
957
1.92
12.75
7.5
4.3
0.96
1.04
%
0.16
68
269
79
328
2.51
12.45
1.3
1.2
4.07
10.63
u/ml
0.84
11
55
340
2348
1.63
12.11
1.9
1.5
2.66
2.30
g/l
1.50
217
1453
428
3124
1.58
12.09
5.7
4.0
0.02
0.00
estimate
0.34
171
1142
581
4564
1.54
11.70
4.5
3.5
6.21
6.25
ph
0.33
313
2591
579
4545
1.54
11.70
15.6
13.2
1.23
1.21
inr
0.44
471
3772
160
912
1.87
11.23
7.5
4.4
0.12
0.13
%
0.05
57
225
279
1874
1.64
10.96
1.8
1.7
—
—
—
0
0
227
1461
1.69
10.47
2.2
1.9
—
—
—
0
0
48
170
2.90
10.32
1.8
1.7
0.73
0.77
g/l
0.07
35
139
159
936
1.81
10.03
8.2
4.6
0.59
0.16
%
0.46
56
212
28
72
3.96
9.89
2.1
1.9
38.18
39.89
%
0.22
28
72
214
1376
1.68
9.87
3.7
3.2
4.36
5.11
e9/l
0.82
188
1220
192
1201
1.71
9.80
1.6
1.3
—
—
—
0
0
391
2906
1.52
9.71
4.2
3.1
1870.19
1108.11
ng/l
0.68
332
2463
70
309
2.35
9.68
3.1
4.1
42.26
62.64
mg/l
0.51
64
263
70
309
2.35
9.68
3.0
4.1
54.43
49.43
mg/l
0.09
64
263
85
410
2.16
9.52
1.9
1.9
1.50
1.53
g/l
0.09
76
364
283
1972
1.57
9.37
3.5
2.8
521.07
512.83
mosm/kgh2o
0.26
244
1745
26
66
4.01
9.35
2.2
2.1
73.69
73.02
%
0.06
26
61
452
3487
1.48
9.25
3.7
3.1
—
—
—
0
0
291
2047
1.56
9.23
1.4
1.3
6.95
11.11
u/ml
0.60
112
774
569
4604
1.45
9.03
2.3
2.1
94.98
97.24
pmol/l
0.52
320
2387
129
735
1.85
9.02
2.6
2.4
25.46
20.26
au/ml
0.29
14
74
654
5444
1.45
8.87
4.1
3.0
113.34
97.99
ug/l
0.97
627
5097
203
1324
1.64
8.80
8.8
5.0
1.04
1.03
mmol/l
0.28
190
1228
119
668
1.87
8.72
1.4
1.3
48.20
38.92
au/ml
—
5
53
713
6073
1.44
8.28
6.1
4.8
6.76
6.57
mmol/l
1.34
679
5724
108
598
1.89
8.26
1.3
1.2
—
—
—
0
0
143
864
1.75
8.22
1.5
1.4
—
—
—
0
0
39
141
2.83
8.13
1.7
1.4
—
—
—
0
0
39
141
2.83
8.13
1.7
1.4
—
—
—
0
0
39
141
2.83
8.13
1.7
1.4
—
—
—
0
0
39
141
2.83
8.13
1.7
1.4
—
—
—
0
0
244
1693
1.56
8.11
1.9
1.7
1220.94
1202.69
nmol/l
0.11
203
1269
128
754
1.78
8.02
1.6
1.3
199.87
207.57
u/ml
0.04
119
694
301
2191
1.50
8.00
1.4
1.3
38.01
32.02
iu/ml
0.26
96
672
47
189
2.55
7.98
4.3
3.9
4.26
4.20
e9/l
0.08
47
189
1092
10225
1.89
7.90
26.7
14.7
23.92
22.15
mg/l
1.05
978
8396
18
39
4.67
7.89
4.2
2.8
35.20
241.76
ug/l
0.45
18
32
427
3337
1.44
7.85
3.0
2.5
64.89
61.73
u/l
0.19
405
3085
533
4339
1.42
7.79
5.2
3.8
0.00
0.04
estimate
3.63
143
998
19
30
6.42
7.72
2.8
2.9
150.75
39.33
au/ml
—
6
6
477
3824
1.41
7.53
4.6
3.6
31.04
58.31
ng/l
0.80
332
2559
244
1719
1.53
7.53
3.5
2.8
0.99
1.10
e6/l
0.25
131
873
155
981
1.67
7.51
2.7
2.2
0.22
0.21
g/l
0.29
140
915
244
1722
1.53
7.46
4.9
3.2
0.82
0.82
mmol/l
0.20
234
1632
60
279
2.21
7.40
3.2
3.9
1.47
3.43
ratio
0.84
40
159
293
2167
1.47
7.09
1.9
1.7
426.58
33407276.05
pmol/l
2.39
249
1814
469
3783
1.40
7.01
3.5
3.4
2.36
2.36
mmol/l
0.32
427
3456
219
1532
1.53
6.94
2.7
2.0
29.55
29.18
s
0.37
212
1482
355
2736
1.43
6.86
1.4
1.3
1.85
1.69
u/ml
0.07
93
756
65
325
2.06
6.69
3.4
3.1
229.89
305.26
mg/l
0.52
36
126
52
239
2.23
6.62
4.7
3.6
60.71
58.61
%
0.63
52
239
26
84
3.14
6.61
1.0
1.1
15.85
14.42
u/ml
—
6
42
21
59
3.61
6.61
2.2
2.1
447.73
501.32
e6/l
0.21
15
47
43
182
2.41
6.60
1.6
1.3
125.13
161.97
au/ml
—
8
51
437
3516
1.39
6.50
4.0
3.3
7.16
7.28
mmol/l
0.22
371
3002
193
1342
1.52
6.26
7.5
6.2
104.51
104.29
mmol/l
0.30
193
1342
130
826
1.64
6.19
8.9
7.5
—
—
—
0
0
1093
10353
1.74
5.98
26.0
17.2
3.94
3.95
mmol/l
0.27
1075
10133
130
834
1.63
5.96
3.2
2.3
0.26
0.45
e6/l
0.68
124
793
17
34
5.06
5.88
2.1
1.8
35.59
28.38
%
1.14
17
34
217
1566
1.47
5.85
3.8
3.0
5.89
3.55
e6/l
1.24
104
722
26
91
2.90
5.80
1.3
1.1
111.31
111.67
pmol/l
0.01
26
91
1091
10341
1.71
5.79
25.7
17.0
139.60
139.64
mmol/l
0.26
1074
10144
178
1238
1.52
5.75
3.9
2.5
6.24
7.41
umol/l
0.56
153
1072
44
202
2.22
5.65
1.5
1.3
—
—
—
0
0
141
935
1.58
5.64
6.4
3.7
7.35
7.36
ph
0.06
116
670
16
32
5.05
5.57
2.0
1.3
—
—
—
0
0
71
395
1.85
5.41
2.8
1.8
21.03
20.58
s
0.51
65
353
376
3024
1.36
5.40
1.8
1.7
18.84
21.03
nmol/l
2.27
328
2572
440
3633
1.34
5.28
3.9
3.1
29.49
30.00
u/l
0.16
414
3438
330
2612
1.37
5.22
5.8
3.8
93.32
92.73
%
0.15
323
2553
96
590
1.68
5.21
4.8
3.7
7.42
7.42
ph
0.59
85
486
20
64
3.16
5.20
1.1
1.0
—
—
—
0
0
922
8502
1.38
5.01
5.4
4.7
14.68
14.68
pmol/l
0.01
852
7872
130
870
1.56
5.00
5.0
4.0
—
—
—
0
0
73
421
1.78
4.97
4.8
3.8
—
—
—
0
0
396
3242
1.33
4.97
4.3
3.4
35.31
39.92
mg/l
0.27
251
2007
403
3309
1.33
4.95
5.1
4.1
7.28
8.04
mg/mmol
0.13
253
2003
140
958
1.52
4.87
5.4
3.4
2.00
2.01
mmol/l
0.01
124
831
23
84
2.77
4.79
1.3
1.2
—
—
—
0
0
50
258
1.98
4.79
1.3
1.2
—
—
—
0
0
43
210
2.09
4.78
1.9
1.7
—
—
—
0
0
176
1269
1.45
4.74
1.7
1.4
—
—
—
0
0
56
302
1.90
4.73
1.3
1.2
260.00
92.90
titre
—
7
31
155
1093
1.48
4.67
7.3
7.6
1.09
1.05
mmol/l
0.05
138
906
393
3237
1.32
4.67
10.0
6.1
—
—
—
0
0
112
739
1.57
4.59
2.9
3.7
4.52
4.53
pmol/l
0.04
106
658
28
116
2.45
4.57
1.8
2.8
—
—
—
0
0
48
249
1.97
4.55
1.7
1.6
13064.30
12666.40
e6/l
0.03
40
176
126
856
1.53
4.54
4.9
3.4
84.45
81.28
ng/l
0.16
113
740
17
54
3.18
4.49
1.1
1.0
—
—
—
0
0
145
1017
1.49
4.49
2.5
2.1
0.00
0.02
estimate
0.78
25
224
25
101
2.51
4.31
1.4
1.1
—
—
—
0
0
384
3186
1.30
4.25
4.5
3.3
0.01
0.10
estimate
0.94
148
983
144
1020
1.47
4.25
2.4
2.3
35.37
38.21
u/l
0.15
114
847
23
90
2.59
4.23
1.3
1.2
—
—
—
0
0
124
853
1.51
4.22
4.6
3.7
1.22
1.23
mmol/l
0.62
109
727
55
307
1.83
4.20
16.1
9.6
—
—
—
0
0
141
997
1.47
4.20
5.5
3.4
5.91
5.82
kpa
0.57
134
969
25
103
2.46
4.15
1.3
1.3
—
—
—
0
0
140
993
1.46
4.10
5.6
3.5
7.37
7.38
ph
0.66
85
568
271
2153
1.34
4.07
2.7
2.7
2.45
2.45
mmol/l
0.06
252
1945
50
274
1.86
4.06
4.4
3.3
2.50
2.43
index
0.03
24
147
311
2525
1.31
4.00
5.4
4.0
1.02
1.61
kg/l
0.50
211
1691
500
4319
1.27
3.98
2.4
2.1
—
—
—
0
0
406
3418
1.29
3.97
3.9
2.2
—
—
—
0
0
81
514
1.62
3.94
2.9
2.1
0.15
1.43
estimate
0.43
20
175
198
1506
1.38
3.93
1.3
1.2
—
—
—
0
0
25
106
2.39
3.92
1.1
1.1
—
—
—
0
0
25
106
2.39
3.92
2.0
2.8
0.86
1.08
g/24h
0.33
11
64
1118
10791
1.67
3.90
30.3
19.0
75.11
72.40
umol/l
1.80
1105
10674
152
1106
1.43
3.90
7.4
7.7
7.43
7.42
ph
1.61
83
638
10
19
5.30
3.83
1.3
1.2
—
—
—
0
0
1112
10724
1.62
3.82
18.4
11.6
24.75
24.88
u/l
0.11
1081
10443
34
167
2.07
3.78
1.2
1.0
—
—
—
0
0
31
147
2.14
3.77
1.3
1.2
—
73.85
—
0
8
26
115
2.29
3.73
2.5
2.2
—
—
—
0
0
12
29
4.17
3.71
1.8
1.4
—
—
—
0
0
10
20
5.03
3.69
1.0
1.0
—
—
—
0
0
377
3171
1.28
3.66
2.5
2.1
112.72
193.38
u/l
3.25
361
3032
32
159
2.04
3.47
1.1
1.2
—
—
—
0
0
776
7126
1.26
3.45
4.5
3.9
—
6313.81
—
0
16
122
875
1.44
3.40
1.3
1.2
196.93
143.85
u/ml
0.65
52
351
1024
9765
1.36
3.27
6.7
5.8
1.91
1.88
mu/l
0.35
965
9142
122
883
1.43
3.24
1.5
1.4
—
—
—
0
0
8
16
5.03
3.05
1.0
1.1
—
—
—
0
0
33
176
1.90
2.98
1.4
1.2
2.63
4.72
u/ml
0.75
19
72
18
75
2.42
2.98
1.3
1.1
—
—
—
0
0
24
115
2.11
2.90
2.0
1.7
65.18
59.70
%
0.32
17
77
24
116
2.09
2.84
1.2
1.3
—
—
—
0
0
125
932
1.38
2.82
7.1
8.1
117.75
120.36
g/l
0.82
125
912
165
1285
1.33
2.81
1.7
1.5
—
—
—
0
0
124
925
1.38
2.79
1.2
1.2
—
—
—
0
0
50
309
1.65
2.77
2.2
2.5
—
—
—
0
0
31
167
1.88
2.73
1.2
1.1
—
—
—
0
0
31
168
1.87
2.69
1.0
1.1
3.20
1.90
eliau/ml
0.66
11
81
34
191
1.80
2.64
1.0
1.1
4.17
16.49
au/ml
—
7
58
10
30
3.35
2.60
1.2
1.3
29.40
28.73
s
—
10
30
10
30
3.35
2.60
1.3
1.3
—
—
—
0
0
41
245
1.70
2.59
1.3
1.5
2380.26
187.37
e6/l
0.65
35
187
41
245
1.70
2.59
1.2
1.5
329.29
7.83
e6/l
0.67
34
179
7
16
4.39
2.47
1.4
1.3
—
—
—
0
0
24
123
1.97
2.46
2.3
2.7
—
38.81
—
0
14
112
841
1.37
2.44
5.1
3.0
4.36
4.47
kpa
0.22
106
815
550
4980
1.20
2.41
3.9
2.7
—
—
estimate
—
0
0
6
12
5.02
2.40
1.0
2.8
0.50
0.67
u/field
—
6
12
17
77
2.23
2.38
1.4
1.4
—
—
—
0
0
916
8703
1.23
2.36
28.9
18.5
13.90
13.57
%
9.19
905
8597
8
22
3.65
2.36
6.8
2.7
—
—
—
0
0
232
1937
1.25
2.30
4.4
3.7
533.85
344.78
ng/l
0.28
174
1406
13
53
2.47
2.28
2.8
1.4
9.33
6.48
ug/l
0.33
13
45
98
729
1.38
2.28
2.9
3.0
208.84
185.16
ng/l
0.18
83
670
16
73
2.21
2.21
1.4
1.3
3426.25
146136.08
e6/l
—
8
36
74
527
1.43
2.21
9.8
9.5
15.51
15.77
%
0.45
74
507
5
10
5.02
2.07
1.2
1.0
50.34
95.26
ng/l
—
5
5
7
20
3.51
2.05
2.1
1.7
—
—
—
0
0
23
125
1.86
2.03
2.3
1.6
46.45
25.15
ng/l
0.42
23
125
11
44
2.51
2.01
1.7
1.7
—
—
—
0
0
98
745
1.34
2.01
3.5
2.3
4.75
6.59
ug/l
0.94
78
665
22
388
0.56
2.00
1.2
1.1
0.73
0.63
ratio
—
5
54
25
422
0.58
1.95
1.2
1.1
1.45
1.58
g/l
2.24
25
422
59
414
1.45
1.94
1.6
1.6
15.91
9.27
u/ml
—
8
87
1085
10569
1.32
1.91
20.0
13.3
—
—
—
0
0
9
34
2.66
1.86
1.9
2.8
0.56
0.62
mmol/l
—
9
34
1134
11129
1.47
1.86
36.7
22.7
90.74
90.90
fl
0.51
1123
11024
384
3431
1.18
1.85
4.1
3.4
—
0.80
—
0
10
17
86
1.99
1.85
1.5
1.3
2174.45
1992.60
e6/l
0.05
11
57
1134
11130
1.46
1.85
36.8
22.8
4.42
4.45
e12/l
1.49
1116
10892
1134
11130
1.46
1.85
36.7
22.7
29.99
30.22
pg
3.85
1123
11024
1134
11130
1.46
1.85
37.5
23.1
39.69
40.01
%
1.54
1122
11019
6
17
3.54
1.84
2.3
1.2
—
—
—
0
0
1134
11132
1.46
1.82
36.9
22.8
6.87
6.67
e9/l
2.27
1116
10885
47
320
1.49
1.81
1.2
1.2
—
—
—
0
0
1134
11135
1.45
1.78
37.2
22.9
131.36
133.65
g/l
6.14
1123
11029
1133
11124
1.45
1.78
36.9
22.8
263.70
257.18
e9/l
2.38
1117
10912
18
95
1.91
1.76
26.5
7.9
6.79
6.99
mmol/l
0.14
13
74
21
117
1.81
1.75
1.0
1.1
—
—
—
0
0
6
18
3.34
1.75
1.3
1.3
—
—
—
0
0
32
203
1.59
1.69
3.6
3.4
—
—
—
0
0
20
111
1.82
1.69
1.2
1.6
—
—
—
0
0
31
196
1.60
1.67
1.1
1.1
0.19
0.79
u/ml
2.29
18
78
35
228
1.55
1.66
1.6
1.8
—
—
—
0
0
34
220
1.56
1.66
1.1
1.5
—
—
—
0
0
23
135
1.72
1.63
7.4
5.3
12.84
12.12
mg/l
0.29
23
124
25
151
1.67
1.60
1.2
1.2
—
—
—
0
0
6
20
3.01
1.58
2.3
1.7
—
—
—
0
0
56
407
1.39
1.56
1.3
1.3
182.84
231.38
miu/ml
0.43
24
191
16
85
1.89
1.55
3.1
2.7
—
—
—
0
0
66
494
1.36
1.55
2.8
2.3
—
—
—
0
0
13
64
2.04
1.54
1.6
2.6
54.17
42.99
%
—
6
37
752
7131
1.15
1.53
3.8
3.2
43.57
43.89
u/l
0.05
708
6735
982
9505
1.20
1.53
7.2
6.1
39.97
38.88
mmol/mol
3.24
927
8947
99
1233
0.78
1.53
1.8
1.9
3.40
3.39
ratio
0.02
71
958
26
162
1.62
1.50
1.0
1.1
0.79
6.85
u/ml
2.68
16
67
31
202
1.55
1.49
1.1
1.1
4.35
3.30
u/ml
0.27
17
102
78
605
1.31
1.45
7.6
7.6
24.47
24.47
mmol/l
0.00
78
583
9
38
2.38
1.45
1.3
1.9
80.27
802.16
nmol/24h
—
9
38
11
52
2.13
1.44
1.1
1.7
—
—
—
0
0
5
16
3.13
1.44
1.2
1.1
—
—
—
0
0
6
22
2.74
1.43
1.0
1.5
—
—
—
0
0
60
450
1.35
1.41
1.1
1.1
—
—
—
0
0
29
433
0.66
1.40
1.2
1.2
0.90
0.88
g/l
0.15
29
433
45
322
1.41
1.40
1.4
1.4
260.60
283.92
ug/g
0.33
25
193
10
47
2.14
1.34
1.7
1.4
133.80
168.59
mmol/24h
—
10
47
28
184
1.53
1.32
1.5
1.4
—
—
—
0
0
39
276
1.43
1.30
1.4
1.2
—
—
—
0
0
86
691
1.26
1.25
1.5
1.3
24.98
27.40
iu/l
0.28
74
600
14
77
1.83
1.25
1.4
1.3
—
—
—
0
0
64
495
1.31
1.25
2.0
2.0
—
—
—
0
0
35
245
1.44
1.24
1.2
1.1
1.93
2.81
u/ml
0.31
20
132
36
254
1.43
1.23
1.2
1.3
3.63
3.73
mmol/l
0.17
36
236
5
19
2.64
1.21
1.2
1.2
—
—
—
0
0
16
93
1.73
1.21
1.0
1.1
—
—
—
0
0
14
78
1.80
1.21
1.3
1.4
—
—
—
0
0
159
1368
1.19
1.21
1.4
1.3
—
—
—
0
0
22
140
1.58
1.20
1.8
2.1
0.80
0.93
%
0.60
17
89
337
3071
1.14
1.19
1.5
1.5
—
—
—
0
0
29
198
1.48
1.17
1.1
1.1
0.22
1.96
u/ml
2.41
17
100
20
126
1.60
1.15
1.6
2.0
33.65
32.21
pg
0.64
20
126
27
185
1.47
1.09
4.1
3.5
0.76
0.86
nmol/l
0.78
21
152
15
89
1.69
1.08
1.2
1.1
—
—
—
0
0
20
129
1.56
1.06
4.7
3.0
—
—
—
0
0
32
229
1.41
1.04
1.8
1.7
47.84
43.04
nmol/l
0.20
32
220
11
60
1.84
1.03
1.0
1.1
0.06
1.00
u/ml
—
5
22
42
316
1.34
1.02
1.6
1.3
12.37
10.21
u/l
0.47
34
255
33
239
1.39
1.01
2.7
2.1
118.09
129.48
g/l
0.84
21
197
25
172
1.46
1.00
1.3
1.2
—
—
—
0
0
17
107
1.60
1.00
4.5
3.3
15.42
11.86
index
0.77
12
70
9
50
1.81
0.96
1.0
1.4
134.44
146.40
nmol/l
—
9
50
20
293
0.68
0.95
1.3
1.4
—
—
—
0
0
15
93
1.62
0.94
2.2
2.3
—
—
—
0
0
12
70
1.72
0.92
5.2
3.5
0.83
0.87
index
0.06
12
70
120
1035
1.18
0.92
3.8
4.1
35.36
19.50
ug/l
0.28
91
848
21
301
0.69
0.90
1.3
1.5
—
—
—
0
0
13
79
1.65
0.88
1.2
1.2
—
—
—
0
0
13
79
1.65
0.88
1.3
1.7
—
—
—
0
0
20
288
0.69
0.88
1.3
1.4
1.35
1.24
mm
0.26
14
208
28
203
1.39
0.88
3.4
3.5
2.98
2.63
mmol/l
0.21
19
137
23
161
1.44
0.87
1.7
1.4
0.54
11.66
nmol/l
0.50
23
154
25
178
1.41
0.86
1.0
1.1
0.50
4.21
u/ml
3.72
16
88
22
153
1.45
0.86
1.0
1.0
0.01
0.26
u/ml
—
10
49
21
145
1.46
0.85
1.7
1.4
0.19
0.32
nmol/l
0.41
16
105
6
31
1.94
0.84
1.0
1.2
—
—
—
0
0
45
356
1.27
0.81
2.0
2.1
4.79
18.89
iu/l
0.46
17
156
39
304
1.29
0.79
1.3
1.2
—
—
—
0
0
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
16
232
0.69
0.75
3.7
4.0
47.96
32.87
u/ml
0.26
16
227
11
67
1.65
0.75
2.0
1.6
100.35
104.67
ng/l
0.04
11
67
5
25
2.00
0.72
6.0
3.4
58.10
51.36
%
—
5
25
10
60
1.67
0.72
1.1
1.3
—
—
—
0
0
396
4187
0.92
0.70
3.2
3.1
—
—
—
0
0
80
929
0.85
0.70
1.6
1.7
3.57
3.45
mmol/l
0.34
51
656
11
70
1.58
0.65
1.2
1.2
—
—
—
0
0
16
112
1.43
0.63
1.1
1.5
—
—
—
0
0
167
1523
1.11
0.61
5.3
5.2
2.72
2.24
ug/l
0.38
148
1375
9
141
0.64
0.60
1.4
1.1
—
—
—
0
0
19
141
1.35
0.56
1.3
1.4
—
—
nmol/l
—
0
0
11
73
1.51
0.56
1.2
1.2
0.49
0.53
ratio
—
5
40
8
55
1.46
0.56
1.3
3.1
16.06
16.03
%
—
8
55
6
37
1.62
0.55
1.0
1.2
76.28
170.71
pmol/l
—
6
37
83
734
1.14
0.52
2.3
3.2
52.26
77.51
u/ml
0.41
78
709
11
75
1.47
0.50
1.3
1.5
12.33
11.51
umol/l
0.13
11
68
55
637
0.86
0.50
1.5
1.7
—
—
—
0
0
24
189
1.28
0.49
1.3
1.7
—
—
—
0
0
60
521
1.16
0.49
2.3
2.1
8715.82
5969.21
u/l
0.25
20
222
142
1308
1.10
0.46
2.0
1.7
—
—
—
0
0
10
69
1.45
0.44
1.6
1.3
86.40
75.45
umol/l
—
10
69
27
220
1.23
0.44
2.0
2.4
47.60
117.22
ug/min
0.96
14
133
53
461
1.16
0.44
4.6
5.9
1.50
1.57
%
0.33
53
438
48
415
1.16
0.43
4.8
6.3
0.81
0.90
%
0.98
48
390
5
31
1.62
0.43
2.8
1.8
40.56
41.36
g/l
—
5
31
8
57
1.41
0.42
1.0
1.1
2066.75
1642.21
miu/ml
—
8
57
91
1003
0.90
0.42
1.4
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
43
371
1.17
0.40
2.8
3.2
95.79
910.95
u/ml
1.39
34
323
59
665
0.88
0.40
1.5
1.6
903.91
990.95
mu/l
0.25
49
557
991
9793
1.07
0.39
5.6
4.9
5.96
5.86
mmol/l
1.59
922
9040
133
1234
1.09
0.38
1.7
1.7
—
—
—
0
0
49
431
1.14
0.37
1.3
1.5
—
—
—
0
0
52
461
1.13
0.35
1.3
1.5
—
—
—
0
0
9
124
0.72
0.35
2.0
2.3
—
—
—
0
0
85
778
1.10
0.34
1.2
1.3
—
—
—
0
0
24
200
1.20
0.34
1.4
1.4
45.44
61.31
mmol/l
2.14
16
166
52
463
1.13
0.33
1.3
1.5
—
—
—
0
0
42
371
1.14
0.31
2.1
1.8
—
—
—
0
0
7
53
1.32
0.31
1.1
1.2
—
—
—
0
0
7
99
0.71
0.30
1.0
1.6
—
—
—
0
0
8
65
1.23
0.27
1.9
2.9
7.75
8.42
mmol/l
—
8
65
5
38
1.32
0.23
1.6
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
208.80
—
0
5
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
7.3
—
10.42
—
0
12
0
12
0.00
0.21
0.0
3.7
—
41.92
—
0
12
50
460
1.09
0.21
1.3
1.5
—
—
—
0
0
100
1056
0.94
0.21
2.0
1.5
—
—
—
0
0
50
462
1.09
0.19
1.3
1.5
—
—
—
0
0
6
53
1.13
0.18
1.0
1.2
14.17
9.60
mm/h
—
6
53
1026
10201
1.04
0.18
6.0
5.6
2.69
2.76
mmol/l
1.57
965
9552
56
526
1.07
0.15
3.3
2.2
11.31
12.02
nmol/l
0.28
51
486
9
80
1.13
0.15
1.0
1.0
—
—
—
0
0
952
9571
0.97
0.13
4.5
4.1
1.31
1.26
mmol/l
1.25
884
8842
19
209
0.91
0.11
6.1
9.3
104.32
105.35
mmol/l
0.47
19
190
32
342
0.93
0.11
1.3
1.3
—
—
—
0
0
19
208
0.91
0.10
6.1
9.3
10.89
11.27
mmol/l
0.31
19
189
447
4420
1.02
0.10
2.1
1.9
1.39
1.33
mmol/l
0.81
368
3798
1000
10038
0.98
0.10
5.2
4.9
1.47
1.52
mmol/l
2.75
938
9379
23
213
1.08
0.09
1.0
1.1
—
—
—
0
0
23
213
1.08
0.09
1.0
1.1
—
—
—
0
0
6
57
1.05
0.08
1.3
1.2
33.52
32.61
nmol/l
—
6
49
872
8680
1.02
0.08
30.6
19.1
329.91
331.72
g/l
6.86
865
8625
8
75
1.07
0.07
1.3
1.2
42.25
35.84
mmol/l
—
8
70
8
77
1.04
0.07
15.4
13.1
0.56
0.63
mmol/l
—
8
69
1010
10073
1.02
0.06
5.3
5.0
4.63
4.72
mmol/l
2.28
947
9465
47
453
1.04
0.06
1.5
1.5
0.30
0.32
mg/l
0.10
18
186
31
296
1.05
0.06
5.0
7.9
1.14
1.31
mmol/l
1.01
31
260
25
237
1.06
0.05
4.8
4.4
—
—
—
0
0
21
221
0.95
0.04
1.7
1.4
0.21
0.38
nmol/l
2.00
14
186
88
864
1.02
0.04
2.8
2.5
6.15
6.07
ph
0.41
61
562
53
537
0.99
0.01
1.1
1.1
—
—
—
0
0
12
118
1.02
0.00
1.6
1.9
90.11
90.47
%
0.11
12
118
91
911
1.00
0.00
3.0
3.1
0.90
0.71
ug/l
0.79
55
565
0
7
0.00
0.00
0.0
1.1
—
17.11
—
0
7
8
82
0.98
0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
376.43
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
172.33
—
0
6
0
6
0.00
-0.00
0.0
2.3
—
0.50
—
0
6
8
79
1.01
-0.00
3.0
1.8
9.63
6.69
mmol/l
—
8
54

Mortality – FinRegistry

↥

Association

Association between endpoint L12_ERYTHEMANODOSUM and mortality.

Females

Parameter HR [95% CI] p-value
L12_ERYTHEMANODOSUM 1.225 [1.06, 1.41] 0.005
Birth year 0.99 [0.98, 1.0] 0.027

During the follow-up period (1.1.1998 — 31.12.2019), 380 out of 3301 females with L12_ERYTHEMANODOSUM died.

Males

Parameter HR [95% CI] p-value
L12_ERYTHEMANODOSUM 1.581 [1.26, 1.98] < 0.001
Birth year 0.984 [0.97, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 148 out of 1122 males with L12_ERYTHEMANODOSUM died.

Mortality risk

Mortality risk for people of age

years, who have L12_ERYTHEMANODOSUM.

N-year risk Females Males
1 0.106% 0.252%
5 0.531% 1.652%
10 1.452% 4.087%
15 2.738% 7.634%
20 5.092% 12.892%

Relationships between endpoints

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Index endpoint: L12_ERYTHEMANODOSUM – Erythema nodosum

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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