erythema infectiosum: usually a benign childhood condition characterized by a classic slapped-cheek appearance (see the image below) and lacy exanthem.It results from infection with human parvovirus (PV) B19, an erythrovirus.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1270 |
4. Check minimum number of eventsNone |
1270 |
5. Include endpointsNone |
1270 |
6. Filter based on genotype QC (FinnGen only) |
1140 |
Control definitions (FinnGen only)
- Control exclude
- L12_URTICARIAERYTHEMA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L50-L54
- Name in latin
- Erythema nodosum
Similar endpoints
↥List of similar endpoints to
Erythema nodosum
based on the number of shared cases.
Similar with more cases:
- Urticaria and erythema
- Diseases of the skin and subcutaneous tissue
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9004 | 6843 | 2116 |
| Only index persons | 7799 | 5941 | 1858 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.20 | 0.06 |
| Only index persons | 0.18 | 0.22 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 40.55 | 41.91 | 36.01 |
| Only index persons | 37.81 | 38.86 | 34.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1140 | 903 | 237 |
| Unadjusted period prevalence (%) | 0.28 | 0.32 | 0.11 |
| Median age at first event (years) | 39.33 | 38.87 | 41.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1182
- Matched controls
- 11820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L52
ICD-10 Finland
Erythema nodosum
1133.5
307.7
716
16
69520
ICD-8 Finland
Erythematous condition, Erythema nodosum
+∞
293.3
269
*
6952A
ICD-9 Finland
Erythematous conditions, Erythema nodosum[ERYTHEMA NODOSUM ACUTUM]
+∞
111.2
105
*
M79.3
ICD-10 Finland
Panniculitis, unspecified
56.5
95.2
54
10
M148, L529,
ICD-10 Finland
+∞
90.8
86
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.5
77.9
215
551
L04AX01
ATC
azathioprine; systemic
6.2
67.8
122
214
D86.0
ICD-10 Finland
Sarcoidosis of lung
12.9
66.3
65
53
H02AB06
ATC
prednisolone; systemic
2.8
65.7
716
4150
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
17.3
63.7
53
32
A46
ICD-10 Finland
Erysipelas
3.2
51.8
248
909
M14.8*L52
ICD-10 Finland
Arthropathy in erythema: nodosum
+∞
43.0
41
*
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
11.4
40.8
43
39
L529, ,
ICD-10 Finland
+∞
39.8
38
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.4
38.7
102
248
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
34.7
618
4028
A07EC02
ATC
mesalazine; oral, rectal
3.7
31.1
105
305
13597
ICD-8 Finland
Sarcoidosis, Suspecta
42.3
30.1
37
9
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
11.8
29.2
30
26
K50.8
ICD-10 Finland
Other Crohn disease
6.8
29.1
46
70
132
Kela drug reimbursment
Sarcoidosis
11.0
28.8
31
29
R50.9
ICD-10 Finland
Fever, unspecified
2.4
27.4
230
1095
H02AB07
ATC
prednisone; oral
2.4
25.3
201
931
J01FF01
ATC
clindamycin; systemic
2.0
23.7
359
2135
R60.0
ICD-10 Finland
Localized oedema
2.4
23.4
186
860
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
8.3
22.7
30
37
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.1
22.7
63
159
K51.5
ICD-10 Finland
Left sided colitis
4.4
22.2
56
131
K50.1
ICD-10 Finland
Crohn disease of large intestine
7.2
22.1
33
47
A02BC02
ATC
pantoprazole; systemic
1.9
21.7
845
6713
TGC00
NOMESCO Finland
Bronchial lavation
4.7
21.6
50
109
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
21.6
172
795
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
21.4
298
1714
J01MA02
ATC
ciprofloxacin; systemic
1.8
21.2
463
3078
M13.9
ICD-10 Finland
Arthritis, unspecified
2.7
21.0
121
480
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
20.2
181
879
UJF32
NOMESCO Finland
Coloscopy
1.9
19.7
328
1995
K50.9
ICD-10 Finland
Crohn disease, unspecified
5.2
19.4
40
79
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
19.3
142
633
L04AA06
ATC
mycophenolic acid; systemic
5.3
19.0
38
73
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.1
18.6
80
270
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
18.4
152
712
D07AC01
ATC
betamethasone; topical
1.8
18.4
449
3055
SPAT1255
SPAT
Intravenous administration of medicine
2.8
18.3
93
345
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
18.2
447
3044
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
3.3
17.9
70
223
E0000UV, ,
ATC
1.7
17.8
531
3811
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
17.7
364
2352
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
7.0
17.0
26
38
TQW80
NOMESCO Finland
Local dermatologic skincare
4.2
16.7
45
111
C03CA01
ATC
furosemide; systemic
1.8
16.6
332
2121
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
16.0
103
431
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.5
15.9
56
167
L04AX03
ATC
methotrexate; systemic
2.2
15.6
141
684
ZX120
NOMESCO Finland
Intravenous
2.3
15.6
130
610
K51.8
ICD-10 Finland
Other ulcerative colitis
5.0
15.5
33
67
M04AA01
ATC
allopurinol; systemic
2.2
15.1
135
652
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
4.3
14.9
39
94
M14.8
ICD-10 Finland
Arthropathies in other specified diseases classified elsewhere
81.1
14.6
16
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.4
14.3
108
485
H02AB04
ATC
methylprednisolone; systemic
2.0
14.2
180
989
J01DA01
ATC
[U] cefalexin
1.6
14.0
735
5948
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
14.0
264
1646
A07EA06
ATC
budesonide; oral, local oral
3.0
14.0
62
213
R60.9
ICD-10 Finland
Oedema, unspecified
2.6
13.9
84
340
127
Kela drug reimbursment
Transplant complication
5.6
13.9
26
47
1350A
ICD-9 Finland
Sarcoidosis[SARCOIDOSIS]
18.5
13.4
20
11
P01BA02
ATC
hydroxychloroquine; oral
2.2
13.4
120
580
A07EA02
ATC
hydrocortisone; rectal
4.1
13.2
36
90
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
13.0
71
274
H02AB09
ATC
hydrocortisone; systemic
3.6
12.9
42
119
SPAT1263
SPAT
Sampling
1.6
12.9
490
3650
M14.8*D86.8
ICD-10 Finland
Arthropathy in sarcoidosis
70.6
12.6
14
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
12.3
100
464
J01MA12
ATC
levofloxacin; systemic
1.8
12.1
205
1233
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
12.1
73
296
J01DB01
ATC
cefalexin; oral
1.7
11.7
970
8575
L04AA01
ATC
[U] ciclosporin
5.6
11.7
22
40
K50.0
ICD-10 Finland
Crohn disease of small intestine
4.0
11.5
32
81
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
11.0
229
1459
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.5
11.0
69
285
S97
ICPC
Chronic ulcer skin
2.3
10.8
80
357
L04AB04
ATC
adalimumab; parenteral
3.4
10.7
39
119
D86.3
ICD-10 Finland
Sarcoidosis of skin
18.0
10.7
16
9
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
10.5
140
780
L17
ICPC
Foot/toe symptom/complaint
1.6
10.4
369
2674
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.7
10.3
55
210
13599
ICD-8 Finland
Sarcoidosis, Unspecified
13.2
10.2
17
13
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.7
10.1
32
89
D07AD01
ATC
clobetasol; topical
1.7
10.0
200
1258
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
10.0
269
1828
S01
ICPC
Pain/tenderness of skin
2.5
9.8
63
263
M30.0
ICD-10 Finland
Polyarteritis nodosa
20.2
9.8
14
7
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.0
9.8
105
543
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
9.7
70
309
S18
ICPC
Laceration/cut
1.5
9.7
531
4203
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.6
436
3320
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.2
9.6
83
395
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
9.2
9.5
19
21
A07EC01
ATC
sulfasalazine; oral, rectal
2.0
9.3
100
517
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
9.3
139
803
C03DA01
ATC
spironolactone; oral
1.8
9.3
135
774
XG410
NOMESCO Finland
Flow-volume spirometry
2.6
9.2
51
199
SPAT1262
SPAT
Handing over of treatment supplies
1.7
9.2
183
1150
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.1
310
2216
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
3.7
9.0
28
77
J01AA02
ATC
doxycycline; systemic
1.5
9.0
884
7795
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.1
9.0
37
122
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
9.0
74
345
R03AC02
ATC
salbutamol; inhalant
1.5
9.0
655
5445
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
8.9
60
257
J01DA09
ATC
[U] cefadroxil
1.5
8.9
304
2176
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
4.7
8.8
20
43
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
8.8
267
1859
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
3.6
8.7
28
79
L04AD01
ATC
ciclosporin; systemic
3.8
8.5
25
66
L50.9
ICD-10 Finland
Urticaria, unspecified
3.5
8.5
29
85
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.4
8.5
30
90
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
8.5
199
1302
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.5
458
3587
WZC00, ,
SPAT
1.7
8.4
177
1126
L95.8
ICD-10 Finland
Other vasculitis limited to skin
12.9
8.4
14
11
B01AB05
ATC
enoxaparin; parenteral
1.5
8.2
349
2605
L01BB02
ATC
mercaptopurine; oral
4.4
8.2
20
46
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.0
8.0
85
438
M79.6
ICD-10 Finland
Pain in limb
1.4
8.0
518
4184
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
7.9
146
896
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.9
475
3780
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.7
7.8
136
821
D07AC13
ATC
mometasone; topical
1.5
7.8
318
2351
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.7
7.8
41
156
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
7.7
59
267
SPAT1260
SPAT
Consultation of another employee
1.6
7.7
192
1273
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
7.7
45
180
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.5
478
3833
D94
ICPC
Chronic enteritis/ulcerative colitis
7.2
7.5
17
24
L01BA01
ATC
methotrexate; systemic
2.5
7.5
46
189
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
7.4
224
1552
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
7.4
136
834
S29
ICPC
Skin symptom/complaint other
1.5
7.4
232
1623
J01FA06
ATC
roxithromycin; oral
1.4
7.4
445
3534
6952C
ICD-9 Finland
Erythematous conditions, Erythema nodosum[VASCULITIS NODULARIS,ERYTHEMA INDURATUM NONTUBERCUL]
+∞
7.3
7
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.3
7.3
52
229
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.2
136
839
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
15.9
7.2
11
7
A08
ICPC
Swelling
2.0
7.1
71
358
L50.8
ICD-10 Finland
Other urticaria
8.0
7.1
15
19
K51
ICD-10 Finland
Ulcerative colitis
4.1
7.1
19
47
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.5
7.1
44
182
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
7.0
253
1821
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
3.4
7.0
24
71
T90
ICPC
Diabetes non-insulin dependent
1.5
7.0
242
1728
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
6.9
144
912
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.4
6.9
44
184
D86
ICD-10 Finland
Sarcoidosis
13.9
6.9
11
8
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.4
6.9
24
72
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
6.8
108
636
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.3
6.8
48
211
XW000
NOMESCO Finland
Bone marrow biopsy
2.4
6.8
44
186
03992
ICD-8 Finland
Other bacterial diseases, Infectio Yersinia (Pasteurella) enterocolitica
40.3
6.8
8
*
R05
ICD-10 Finland
Cough
1.5
6.7
249
1800
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
6.7
105
616
J02AC01
ATC
fluconazole; systemic
1.4
6.7
480
3910
S76
ICPC
Skin infection other
2.1
6.6
63
312
E000001, ,
ATC
1.5
6.6
216
1520
J04BA02
ATC
dapsone; oral
7.9
6.6
14
18
XQ848
NOMESCO Finland
Dermatological photography
2.6
6.6
36
140
M25.5
ICD-10 Finland
Pain in joint
1.4
6.5
392
3096
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
6.5
60
294
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
6.5
236
1699
B01AB10
ATC
tinzaparin; parenteral
1.7
6.5
126
785
L04AD02
ATC
tacrolimus; systemic
5.7
6.5
17
30
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.0
6.5
18
46
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
4.0
6.5
18
46
A18.4
ICD-10 Finland
Tuberculosis of skin and subcutaneous tissue
70.2
6.4
7
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.5
6.4
38
154
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
6.3
133
845
H15.1
ICD-10 Finland
Episcleritis
3.2
6.3
24
76
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.5
6.2
39
162
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
6.2
43
187
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
7.1
6.2
14
20
R06AE07
ATC
cetirizine; oral
1.4
6.2
498
4114
SPAT1229
SPAT
Assessment of need for aid
1.9
6.2
78
427
M05BA04
ATC
alendronic acid; oral
1.7
6.2
103
615
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
6.2
238
1733
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
6.1
121
758
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
6.1
105
634
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.4
6.0
38
159
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
272
444
7.66
167.00
2.9
2.1
40.70
39.32
u/l
0.47
254
404
209
268
9.26
157.46
2.9
2.3
11.98
11.97
mg/l
0.01
197
255
146
359
4.50
54.99
1.5
1.5
0.26
0.06
iu/ml
0.37
32
59
297
1492
2.32
31.69
4.3
2.4
135.20
119.98
ug/g
0.36
252
1174
72
173
4.37
27.63
1.5
1.2
388.89
147.27
titre
—
9
11
99
302
3.49
27.17
2.1
1.7
0.24
0.24
g/l
0.03
94
288
101
317
3.39
26.51
1.9
1.6
1.22
1.21
g/l
0.13
96
299
73
191
4.01
25.02
6.2
5.3
570.31
323.76
iu/ml
0.22
13
21
803
6141
1.96
24.93
14.4
9.3
4.24
4.06
e9/l
1.56
739
5353
72
188
4.01
24.74
1.3
1.3
266.37
242.06
u/ml
0.28
46
110
76
208
3.84
24.46
1.8
2.0
4.51
5.03
mmol/24h
0.76
69
185
36
51
7.25
24.26
1.2
1.1
175.59
186.54
iu/ml
0.09
36
51
118
451
2.80
21.98
1.9
1.7
3.98
7.26
iu/ml
1.36
27
104
638
4646
1.81
21.78
7.1
4.7
35.51
36.01
g/l
1.50
609
4385
214
1084
2.19
21.60
5.5
4.2
251.46
247.56
u/l
0.10
204
1031
698
5234
1.81
21.48
9.6
6.7
1.22
1.22
mmol/l
0.13
608
4531
635
4662
1.78
20.66
8.3
6.1
1.21
1.22
mmol/l
0.41
599
4304
940
7822
1.99
19.86
7.7
4.3
16.09
11.98
mm/h
10.90
895
7329
171
832
2.23
18.92
4.1
2.8
10.73
10.45
g/l
0.33
160
767
394
2564
1.80
18.91
3.3
2.5
327.18
328.08
umol/l
0.06
353
2274
159
751
2.29
18.89
1.6
1.6
—
—
—
0
0
203
1065
2.09
18.53
2.5
2.1
346.58
382.33
nmol/l
1.75
192
992
377
2440
1.80
18.32
2.1
1.7
1.14
1.08
mg/l
0.15
295
1883
343
2182
1.81
17.52
1.8
1.6
—
—
—
0
0
943
7977
1.90
17.29
12.8
7.8
78.27
78.15
u/l
0.04
909
7576
468
3290
1.70
16.61
4.2
3.2
83.19
81.85
e6/l
0.01
368
2491
277
1675
1.85
16.57
2.2
1.9
—
—
—
0
0
53
151
3.63
16.11
2.9
3.0
—
2541.36
—
0
11
722
5719
1.67
15.97
5.2
3.9
0.00
4.01
estimate
1.07
177
1227
715
5666
1.66
15.63
5.2
3.9
0.00
0.00
estimate
0.50
173
1196
349
2298
1.74
15.52
3.2
2.6
6.04
7.04
e6/l
0.74
317
2107
247
1480
1.85
15.06
3.3
2.4
19.65
22.29
%
3.04
228
1386
721
5769
1.64
14.77
5.2
4.0
0.00
0.26
estimate
0.51
175
1159
278
1737
1.79
14.73
3.4
2.4
11.56
12.98
umol/l
3.31
264
1616
694
5513
1.63
14.53
8.0
6.1
10.01
11.09
umol/l
3.15
674
5261
158
823
2.06
14.52
3.2
2.6
74.18
72.76
e9/l
0.14
113
591
651
5095
1.62
14.45
3.3
2.5
76.91
77.60
nmol/l
0.26
612
4636
101
440
2.42
14.34
1.3
1.3
0.24
1.15
u/ml
0.79
15
29
836
6985
1.67
14.06
6.2
4.7
317.50
1658.61
e6/l
—
8
100
404
2826
1.65
14.06
3.9
3.1
0.27
0.42
e6/l
1.77
305
2056
133
659
2.15
13.92
2.2
1.8
1.01
1.40
g/l
2.54
123
609
399
2811
1.63
13.35
3.1
2.2
3.24
2.82
mg/l
2.21
352
2421
152
811
2.00
13.03
3.0
3.0
67.33
67.00
g/l
0.23
143
748
80
327
2.55
13.01
1.3
1.2
2.38
2.44
u/ml
—
8
32
605
4726
1.57
12.98
17.5
11.0
0.00
0.00
e9/l
0.18
518
3893
256
1615
1.75
12.94
3.3
2.4
2.36
2.35
g/l
0.18
236
1494
74
294
2.62
12.76
2.8
2.7
—
—
—
0
0
79
328
2.51
12.45
1.3
1.2
4.07
10.63
u/ml
0.84
11
55
62
230
2.79
12.21
2.8
1.6
—
—
—
0
0
340
2348
1.63
12.11
1.9
1.5
2.66
2.30
g/l
1.50
217
1453
428
3124
1.58
12.09
5.7
4.0
0.02
0.00
estimate
0.34
171
1142
68
268
2.63
11.92
1.6
1.5
—
—
—
0
0
579
4545
1.54
11.70
15.6
13.2
1.23
1.21
inr
0.44
471
3772
69
278
2.57
11.58
1.7
1.5
—
—
—
0
0
50
173
2.97
11.18
1.7
1.6
—
—
—
0
0
71
299
2.46
10.87
2.9
2.2
3.68
3.66
g/l
0.03
66
286
50
183
2.81
10.13
1.9
1.4
—
—
—
0
0
391
2906
1.52
9.71
4.2
3.1
1870.19
1108.11
ng/l
0.68
332
2463
70
309
2.35
9.68
3.0
4.1
54.43
49.43
mg/l
0.09
64
263
70
309
2.35
9.68
3.1
4.1
42.26
62.64
mg/l
0.51
64
263
85
410
2.16
9.52
1.9
1.9
1.50
1.53
g/l
0.09
76
364
291
2047
1.56
9.23
1.4
1.3
6.95
11.11
u/ml
0.60
112
774
39
131
3.04
9.22
1.6
1.5
—
—
—
0
0
196
1255
1.67
9.14
2.1
1.8
—
—
—
0
0
25
63
4.03
9.08
2.4
2.2
—
—
—
0
0
569
4604
1.45
9.03
2.3
2.1
94.98
97.24
pmol/l
0.52
320
2387
129
735
1.85
9.02
2.6
2.4
25.46
20.26
au/ml
0.29
14
74
654
5444
1.45
8.87
4.1
3.0
113.34
97.99
ug/l
0.97
627
5097
203
1324
1.64
8.80
8.8
5.0
1.04
1.03
mmol/l
0.28
190
1228
119
668
1.87
8.72
1.4
1.3
48.20
38.92
au/ml
—
5
53
713
6073
1.44
8.28
6.1
4.8
6.76
6.57
mmol/l
1.34
679
5724
244
1693
1.56
8.11
1.9
1.7
1220.94
1202.69
nmol/l
0.11
203
1269
58
256
2.33
8.06
1.6
1.4
—
—
—
0
0
128
754
1.78
8.02
1.6
1.3
199.87
207.57
u/ml
0.04
119
694
301
2191
1.50
8.00
1.4
1.3
38.01
32.02
iu/ml
0.26
96
672
1092
10225
1.89
7.90
26.7
14.7
23.92
22.15
mg/l
1.05
978
8396
18
39
4.67
7.89
4.2
2.8
35.20
241.76
ug/l
0.45
18
32
184
1202
1.63
7.88
2.1
1.8
—
—
—
0
0
427
3337
1.44
7.85
3.0
2.5
64.89
61.73
u/l
0.19
405
3085
533
4339
1.42
7.79
5.2
3.8
0.00
0.04
estimate
3.63
143
998
20
48
4.22
7.75
1.5
1.6
—
—
—
0
0
20
48
4.22
7.75
1.5
1.6
—
—
—
0
0
19
30
6.42
7.72
2.8
2.9
150.75
39.33
au/ml
—
6
6
477
3824
1.41
7.53
4.6
3.6
31.04
58.31
ng/l
0.80
332
2559
244
1719
1.53
7.53
3.5
2.8
0.99
1.10
e6/l
0.25
131
873
155
981
1.67
7.51
2.7
2.2
0.22
0.21
g/l
0.29
140
915
244
1722
1.53
7.46
4.9
3.2
0.82
0.82
mmol/l
0.20
234
1632
60
279
2.21
7.40
3.2
3.9
1.47
3.43
ratio
0.84
40
159
58
266
2.24
7.39
1.5
1.5
—
—
—
0
0
54
243
2.28
7.20
1.5
1.3
—
—
—
0
0
293
2167
1.47
7.09
1.9
1.7
426.58
33407276.05
pmol/l
2.39
249
1814
469
3783
1.40
7.01
3.5
3.4
2.36
2.36
mmol/l
0.32
427
3456
48
208
2.36
6.98
1.3
1.6
—
—
—
0
0
35
130
2.74
6.97
1.7
1.5
—
—
—
0
0
219
1532
1.53
6.94
2.7
2.0
29.55
29.18
s
0.37
212
1482
355
2736
1.43
6.86
1.4
1.3
1.85
1.69
u/ml
0.07
93
756
26
84
3.14
6.61
1.0
1.1
15.85
14.42
u/ml
—
6
42
21
59
3.61
6.61
2.2
2.1
447.73
501.32
e6/l
0.21
15
47
43
182
2.41
6.60
1.6
1.3
125.13
161.97
au/ml
—
8
51
45
195
2.36
6.56
1.5
1.4
—
—
—
0
0
437
3516
1.39
6.50
4.0
3.3
7.16
7.28
mmol/l
0.22
371
3002
40
165
2.47
6.49
1.3
1.4
—
—
—
0
0
61
303
2.07
6.40
1.4
1.3
—
—
—
0
0
68
354
1.98
6.28
2.0
1.9
—
—
—
0
0
193
1342
1.52
6.26
7.5
6.2
104.51
104.29
mmol/l
0.30
193
1342
62
313
2.04
6.23
1.3
1.2
—
—
—
0
0
57
282
2.07
6.05
1.3
1.2
44.52
44.42
u/ml
—
6
30
63
324
2.00
6.03
1.7
1.8
—
—
—
0
0
1093
10353
1.74
5.98
26.0
17.2
3.94
3.95
mmol/l
0.27
1075
10133
130
834
1.63
5.96
3.2
2.3
0.26
0.45
e6/l
0.68
124
793
217
1566
1.47
5.85
3.8
3.0
5.89
3.55
e6/l
1.24
104
722
88
511
1.78
5.82
4.5
3.6
1.85
1.81
mmol/l
0.03
69
383
26
91
2.90
5.80
1.3
1.1
111.31
111.67
pmol/l
0.01
26
91
1091
10341
1.71
5.79
25.7
17.0
139.60
139.64
mmol/l
0.26
1074
10144
178
1238
1.52
5.75
3.9
2.5
6.24
7.41
umol/l
0.56
153
1072
28
105
2.71
5.52
1.5
1.5
—
—
—
0
0
63
335
1.93
5.50
1.2
1.3
—
—
—
0
0
54
272
2.03
5.49
1.3
1.1
2.42
4.47
—
6
40
376
3024
1.36
5.40
1.8
1.7
18.84
21.03
nmol/l
2.27
328
2572
440
3633
1.34
5.28
3.9
3.1
29.49
30.00
u/l
0.16
414
3438
65
355
1.88
5.25
2.9
2.4
0.46
0.89
g/l
0.66
58
309
330
2612
1.37
5.22
5.8
3.8
93.32
92.73
%
0.15
323
2553
922
8502
1.38
5.01
5.4
4.7
14.68
14.68
pmol/l
0.01
852
7872
1040
9802
1.51
5.00
22.2
14.2
83.32
82.96
ml/min/173m2
0.19
970
9057
403
3309
1.33
4.95
5.1
4.1
7.28
8.04
mg/mmol
0.13
253
2003
23
83
2.81
4.89
2.2
1.4
—
—
—
0
0
140
958
1.52
4.87
5.4
3.4
2.00
2.01
mmol/l
0.01
124
831
39
183
2.17
4.79
1.5
1.4
—
—
—
0
0
39
183
2.17
4.79
1.5
1.4
—
—
—
0
0
27
108
2.54
4.73
1.3
1.2
—
—
—
0
0
155
1093
1.48
4.67
7.3
7.6
1.09
1.05
mmol/l
0.05
138
906
37
173
2.18
4.60
1.4
1.2
4.63
3.96
u/ml
0.08
19
54
23
86
2.71
4.60
1.3
1.2
—
—
—
0
0
112
739
1.57
4.59
2.9
3.7
4.52
4.53
pmol/l
0.04
106
658
24
92
2.64
4.58
1.5
1.6
—
—
—
0
0
48
249
1.97
4.55
1.7
1.6
13064.30
12666.40
e6/l
0.03
40
176
126
856
1.53
4.54
4.9
3.4
84.45
81.28
ng/l
0.16
113
740
42
208
2.06
4.52
1.3
1.4
—
—
—
0
0
23
87
2.68
4.50
1.3
1.2
—
—
—
0
0
11
19
5.83
4.44
1.4
1.1
104.45
102.32
%
0.10
11
19
30
132
2.31
4.31
1.2
1.3
—
—
—
0
0
30
132
2.31
4.31
1.2
1.3
—
—
—
0
0
384
3186
1.30
4.25
4.5
3.3
0.01
0.10
estimate
0.94
148
983
144
1020
1.47
4.25
2.4
2.3
35.37
38.21
u/l
0.15
114
847
23
90
2.59
4.23
1.3
1.2
—
—
—
0
0
23
90
2.59
4.23
1.3
1.2
—
—
—
0
0
124
853
1.51
4.22
4.6
3.7
1.22
1.23
mmol/l
0.62
109
727
757
6853
1.29
4.21
3.5
3.3
—
—
—
0
0
141
997
1.47
4.20
5.5
3.4
5.91
5.82
kpa
0.57
134
969
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
47
250
1.92
4.16
5.2
2.7
0.38
0.38
iu/ml
0.01
28
135
271
2153
1.34
4.07
2.7
2.7
2.45
2.45
mmol/l
0.06
252
1945
114
777
1.52
4.06
1.6
1.4
—
—
—
0
0
50
274
1.86
4.06
4.4
3.3
2.50
2.43
index
0.03
24
147
19
69
2.78
4.03
1.4
1.2
—
—
—
0
0
311
2525
1.31
4.00
5.4
4.0
1.02
1.61
kg/l
0.50
211
1691
54
305
1.81
3.99
2.4
2.2
0.00
0.00
g/l
-0.00
49
267
29
131
2.24
3.95
1.2
1.2
—
—
—
0
0
60
352
1.74
3.91
1.4
1.3
—
—
—
0
0
1118
10791
1.67
3.90
30.3
19.0
75.11
72.40
umol/l
1.80
1105
10674
1112
10724
1.62
3.82
18.4
11.6
24.75
24.88
u/l
0.11
1081
10443
35
174
2.04
3.77
1.2
1.3
—
—
—
0
0
23
96
2.42
3.74
1.3
1.1
—
—
—
0
0
142
1030
1.43
3.71
3.5
3.3
—
—
—
0
0
377
3171
1.28
3.66
2.5
2.1
112.72
193.38
u/l
3.25
361
3032
80
518
1.58
3.60
1.5
1.5
—
—
—
0
0
312
2569
1.29
3.57
3.6
2.2
—
—
—
0
0
27
124
2.20
3.56
1.3
1.3
—
—
—
0
0
27
124
2.20
3.56
1.3
1.3
—
—
—
0
0
6
6
10.04
3.50
2.8
1.7
2.27
3.15
mg/l
—
6
6
6
6
10.04
3.50
1.7
1.2
—
—
—
0
0
27
125
2.19
3.50
1.3
1.3
—
—
—
0
0
122
875
1.44
3.40
1.3
1.2
196.93
143.85
u/ml
0.65
52
351
1024
9765
1.36
3.27
6.7
5.8
1.91
1.88
mu/l
0.35
965
9142
30
149
2.04
3.27
1.0
1.1
—
0.87
—
0
7
84
564
1.53
3.25
1.9
1.7
—
—
—
0
0
20
84
2.40
3.24
1.4
1.4
—
—
—
0
0
20
84
2.40
3.24
1.4
1.4
—
—
—
0
0
20
84
2.40
3.24
1.4
1.4
—
—
—
0
0
30
150
2.03
3.22
1.2
1.3
—
—
—
0
0
11
29
3.82
3.19
1.1
1.1
—
—
—
0
0
172
1324
1.35
3.16
2.2
2.0
—
—
—
0
0
19
80
2.40
3.07
1.1
1.0
—
—
—
0
0
7
12
5.86
3.02
2.4
1.8
—
—
—
0
0
26
127
2.07
2.98
1.2
1.2
—
—
—
0
0
33
176
1.90
2.98
1.4
1.2
2.63
4.72
u/ml
0.75
19
72
184
1445
1.32
2.96
2.5
2.2
—
—
—
0
0
31
163
1.93
2.92
1.1
1.1
—
—
—
0
0
11
32
3.46
2.90
2.3
1.4
—
—
—
0
0
24
115
2.11
2.90
2.0
1.7
65.18
59.70
%
0.32
17
77
14
52
2.71
2.89
1.4
1.2
—
—
—
0
0
146
1112
1.36
2.88
9.0
6.5
—
—
—
0
0
125
932
1.38
2.82
7.1
8.1
117.75
120.36
g/l
0.82
125
912
18
78
2.33
2.75
1.3
1.5
—
—
—
0
0
31
168
1.87
2.69
1.0
1.1
3.20
1.90
eliau/ml
0.66
11
81
34
191
1.80
2.64
1.0
1.1
4.17
16.49
au/ml
—
7
58
41
245
1.70
2.59
1.2
1.5
329.29
7.83
e6/l
0.67
34
179
41
245
1.70
2.59
1.3
1.5
2380.26
187.37
e6/l
0.65
35
187
104
764
1.40
2.58
2.2
1.9
—
—
—
0
0
11
36
3.07
2.56
1.2
1.1
—
—
—
0
0
108
804
1.38
2.48
2.8
2.4
64.94
67.91
ml/min/173m2
0.37
50
347
23
116
2.00
2.46
2.0
2.4
14.50
24.44
mg/l
—
6
51
112
841
1.37
2.44
5.1
3.0
4.36
4.47
kpa
0.22
106
815
550
4980
1.20
2.41
3.9
2.7
—
—
estimate
—
0
0
6
12
5.02
2.40
1.0
2.8
0.50
0.67
u/field
—
6
12
6
12
5.02
2.40
2.2
1.3
—
—
—
0
0
71
494
1.47
2.38
5.6
3.9
47.58
47.24
%
0.04
71
483
916
8703
1.23
2.36
28.9
18.5
13.90
13.57
%
9.19
905
8597
12
46
2.63
2.36
1.5
1.4
—
—
—
0
0
12
46
2.63
2.36
1.5
1.4
—
—
—
0
0
12
46
2.63
2.36
1.5
1.4
—
—
—
0
0
12
46
2.63
2.36
1.5
1.4
—
—
—
0
0
232
1937
1.25
2.30
4.4
3.7
533.85
344.78
ng/l
0.28
174
1406
13
53
2.47
2.28
2.8
1.4
9.33
6.48
ug/l
0.33
13
45
98
729
1.38
2.28
2.9
3.0
208.84
185.16
ng/l
0.18
83
670
16
73
2.21
2.21
1.4
1.3
3426.25
146136.08
e6/l
—
8
36
74
527
1.43
2.21
9.8
9.5
15.51
15.77
%
0.45
74
507
14
61
2.31
2.15
1.4
1.2
—
—
—
0
0
48
315
1.55
2.14
1.2
1.1
—
—
—
0
0
5
10
5.02
2.07
1.2
1.0
50.34
95.26
ng/l
—
5
5
5
10
5.02
2.07
4.6
4.8
—
—
—
0
0
23
125
1.86
2.03
2.3
1.6
46.45
25.15
ng/l
0.42
23
125
98
745
1.34
2.01
3.5
2.3
4.75
6.59
ug/l
0.94
78
665
14
63
2.24
2.01
1.4
1.3
—
—
—
0
0
22
388
0.56
2.00
1.2
1.1
0.73
0.63
ratio
—
5
54
28
164
1.72
1.96
1.1
1.1
—
—
—
0
0
25
422
0.58
1.95
1.2
1.1
1.45
1.58
g/l
2.24
25
422
59
414
1.45
1.94
1.6
1.6
15.91
9.27
u/ml
—
8
87
47
315
1.51
1.93
1.2
1.1
—
—
—
0
0
17
85
2.01
1.90
2.3
2.1
—
—
—
0
0
22
121
1.83
1.89
1.0
1.1
—
—
—
0
0
9
34
2.66
1.86
1.9
2.8
0.56
0.62
mmol/l
—
9
34
1134
11129
1.47
1.86
36.7
22.7
90.74
90.90
fl
0.51
1123
11024
17
86
1.99
1.85
1.5
1.3
2174.45
1992.60
e6/l
0.05
11
57
1134
11130
1.46
1.85
37.5
23.1
39.69
40.01
%
1.54
1122
11019
1134
11130
1.46
1.85
36.8
22.8
4.42
4.45
e12/l
1.49
1116
10892
6
17
3.54
1.84
1.0
1.1
—
—
—
0
0
6
17
3.54
1.84
2.5
1.3
—
—
—
0
0
1134
11132
1.46
1.82
36.9
22.8
6.87
6.67
e9/l
2.27
1116
10885
15
73
2.07
1.81
1.3
1.2
—
88.20
—
0
5
1134
11135
1.45
1.78
37.2
22.9
131.36
133.65
g/l
6.14
1123
11029
1133
11124
1.45
1.78
36.9
22.8
263.70
257.18
e9/l
2.38
1117
10912
14
67
2.10
1.76
1.1
1.4
—
—
—
0
0
18
95
1.91
1.76
26.5
7.9
6.79
6.99
mmol/l
0.14
13
74
10
40
2.51
1.66
3.6
4.7
—
—
—
0
0
23
135
1.72
1.63
7.4
5.3
12.84
12.12
mg/l
0.29
23
124
79
603
1.33
1.62
1.3
1.4
—
—
—
0
0
8
32
2.51
1.60
1.9
1.4
14.79
8.36
ug/l
—
8
32
19
106
1.81
1.59
3.4
3.6
—
—
—
0
0
56
407
1.39
1.56
1.3
1.3
182.84
231.38
miu/ml
0.43
24
191
16
85
1.89
1.55
2.1
1.7
—
—
—
0
0
8
33
2.43
1.54
1.8
1.5
—
—
—
0
0
8
33
2.43
1.54
1.8
1.5
—
—
—
0
0
752
7131
1.15
1.53
3.8
3.2
43.57
43.89
u/l
0.05
708
6735
982
9505
1.20
1.53
7.2
6.1
39.97
38.88
mmol/mol
3.24
927
8947
99
1233
0.78
1.53
1.8
1.9
3.40
3.39
ratio
0.02
71
958
5
15
3.34
1.52
1.2
1.0
—
—
—
0
0
26
162
1.62
1.50
1.0
1.1
0.79
6.85
u/ml
2.68
16
67
31
202
1.55
1.49
1.1
1.1
4.35
3.30
u/ml
0.27
17
102
14
72
1.96
1.49
1.4
1.2
—
—
—
0
0
13
65
2.01
1.49
1.3
1.1
—
—
—
0
0
78
605
1.31
1.45
7.6
7.6
24.47
24.47
mmol/l
0.00
78
583
9
38
2.38
1.45
1.3
1.9
80.27
802.16
nmol/24h
—
9
38
29
433
0.66
1.40
1.2
1.2
0.90
0.88
g/l
0.15
29
433
45
322
1.41
1.40
1.4
1.4
260.60
283.92
ug/g
0.33
25
193
14
74
1.90
1.39
1.0
1.1
1.17
1.11
u/l
—
6
34
10
47
2.14
1.34
1.7
1.4
133.80
168.59
mmol/24h
—
10
47
8
34
2.36
1.29
1.6
1.5
—
—
—
0
0
5
18
2.78
1.28
1.0
1.2
—
—
—
0
0
86
691
1.26
1.25
1.5
1.3
24.98
27.40
iu/l
0.28
74
600
35
245
1.44
1.24
1.2
1.1
1.93
2.81
u/ml
0.31
20
132
15
85
1.77
1.23
1.0
1.4
—
—
—
0
0
36
254
1.43
1.23
1.2
1.3
3.63
3.73
mmol/l
0.17
36
236
17
101
1.69
1.20
1.1
1.9
—
—
—
0
0
111
924
1.22
1.19
2.5
2.0
—
—
—
0
0
29
198
1.48
1.17
1.1
1.1
0.22
1.96
u/ml
2.41
17
100
20
126
1.60
1.15
1.6
2.0
33.65
32.21
pg
0.64
20
126
12
65
1.85
1.13
1.0
1.1
—
—
—
0
0
27
185
1.47
1.09
4.1
3.5
0.76
0.86
nmol/l
0.78
21
152
32
229
1.41
1.04
1.8
1.7
47.84
43.04
nmol/l
0.20
32
220
15
90
1.68
1.04
1.3
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
60
1.84
1.03
1.0
1.2
—
—
—
0
0
42
316
1.34
1.02
1.6
1.3
12.37
10.21
u/l
0.47
34
255
25
357
0.69
1.02
1.4
1.4
0.94
1.22
ratio
1.18
13
218
25
357
0.69
1.02
1.4
1.4
0.92
0.93
ratio
0.04
13
218
25
357
0.69
1.02
1.4
1.4
1.07
1.16
ratio
0.12
13
218
10
53
1.89
1.01
1.2
1.2
—
—
—
0
0
33
239
1.39
1.01
2.7
2.1
118.09
129.48
g/l
0.84
21
197
12
68
1.77
1.00
1.2
1.4
—
418.57
—
0
7
17
107
1.60
1.00
4.5
3.3
15.42
11.86
index
0.77
12
70
0
29
0.00
0.97
0.0
1.2
—
—
—
0
0
25
353
0.70
0.97
1.3
1.4
—
—
—
0
0
61
489
1.26
0.95
1.6
1.4
—
—
—
0
0
53
418
1.28
0.94
1.9
1.6
—
—
—
0
0
12
70
1.72
0.92
5.2
3.5
0.83
0.87
index
0.06
12
70
120
1035
1.18
0.92
3.8
4.1
35.36
19.50
ug/l
0.28
91
848
10
55
1.83
0.92
1.1
1.3
—
1743.52
—
0
9
6
30
2.00
0.87
1.0
1.1
109.00
106.79
%
—
6
24
23
161
1.44
0.87
1.7
1.4
0.54
11.66
nmol/l
0.50
23
154
25
178
1.41
0.86
1.0
1.1
0.50
4.21
u/ml
3.72
16
88
22
153
1.45
0.86
1.0
1.0
0.01
0.26
u/ml
—
10
49
8
44
1.82
0.86
3.9
3.0
2.94
1.17
%
—
8
44
21
145
1.46
0.85
1.7
1.4
0.19
0.32
nmol/l
0.41
16
105
10
57
1.76
0.83
1.0
1.2
—
—
—
0
0
8
46
1.74
0.82
1.0
1.2
—
—
—
0
0
11
65
1.70
0.82
1.2
1.4
—
60.00
—
0
5
13
81
1.61
0.81
1.2
1.1
—
—
—
0
0
45
356
1.27
0.81
2.0
2.1
4.79
18.89
iu/l
0.46
17
156
0
26
0.00
0.78
0.0
1.2
—
67.96
—
0
26
9
53
1.70
0.75
1.2
1.2
—
—
—
0
0
16
232
0.69
0.75
3.7
4.0
47.96
32.87
u/ml
0.26
16
227
11
67
1.65
0.75
2.0
1.6
100.35
104.67
ng/l
0.04
11
67
7
39
1.80
0.72
1.3
1.1
—
—
—
0
0
7
39
1.80
0.72
1.3
1.1
—
—
—
0
0
7
40
1.75
0.71
2.0
2.2
—
—
—
0
0
15
101
1.49
0.70
1.6
1.2
—
—
—
0
0
80
929
0.85
0.70
1.6
1.7
3.57
3.45
mmol/l
0.34
51
656
30
231
1.31
0.68
1.4
1.6
53.17
56.32
ug/l
0.19
30
231
15
103
1.46
0.65
1.0
1.1
—
—
—
0
0
167
1523
1.11
0.61
5.3
5.2
2.72
2.24
ug/l
0.38
148
1375
140
1264
1.12
0.61
1.5
1.8
1.45
1.42
%
0.15
121
1120
12
80
1.51
0.60
1.2
1.1
—
—
—
0
0
35
431
0.81
0.59
1.5
1.4
—
—
—
0
0
6
35
1.72
0.57
1.2
1.1
—
—
—
0
0
6
35
1.72
0.57
1.0
1.1
26.93
32.01
u/ml
—
6
35
6
36
1.67
0.56
1.0
1.0
—
—
—
0
0
11
73
1.51
0.56
1.2
1.2
0.49
0.53
ratio
—
5
40
6
37
1.62
0.55
1.2
1.2
—
—
—
0
0
6
37
1.62
0.55
1.0
1.2
76.28
170.71
pmol/l
—
6
37
6
37
1.62
0.55
1.0
1.3
—
—
—
0
0
134
1220
1.11
0.53
5.2
4.7
32.37
32.82
%
0.21
102
811
83
734
1.14
0.52
2.3
3.2
52.26
77.51
u/ml
0.41
78
709
11
75
1.47
0.50
1.3
1.5
12.33
11.51
umol/l
0.13
11
68
23
180
1.28
0.50
1.8
1.6
—
—
—
0
0
60
521
1.16
0.49
2.3
2.1
8715.82
5969.21
u/l
0.25
20
222
34
280
1.22
0.49
1.9
1.8
—
—
—
0
0
239
2247
1.08
0.48
1.5
1.5
—
—
—
0
0
10
69
1.45
0.44
1.6
1.3
86.40
75.45
umol/l
—
10
69
27
220
1.23
0.44
2.0
2.4
47.60
117.22
ug/min
0.96
14
133
53
461
1.16
0.44
4.6
5.9
1.50
1.57
%
0.33
53
438
5
31
1.62
0.43
2.8
1.8
40.56
41.36
g/l
—
5
31
8
57
1.41
0.42
1.0
1.1
2066.75
1642.21
miu/ml
—
8
57
37
314
1.18
0.41
1.6
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
43
371
1.17
0.40
2.8
3.2
95.79
910.95
u/ml
1.39
34
323
59
665
0.88
0.40
1.5
1.6
903.91
990.95
mu/l
0.25
49
557
991
9793
1.07
0.39
5.6
4.9
5.96
5.86
mmol/l
1.59
922
9040
6
43
1.40
0.35
1.3
1.5
—
—
—
0
0
131
1223
1.08
0.34
4.1
4.5
23.89
21.51
%
0.64
59
542
6
46
1.31
0.33
1.0
1.1
—
—
—
0
0
11
83
1.33
0.32
1.0
1.1
—
—
—
0
0
14
114
1.23
0.25
1.3
1.1
—
—
—
0
0
15
179
0.84
0.23
1.1
1.2
—
—
—
0
0
17
144
1.18
0.22
1.3
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
1.34
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
53
1.13
0.18
1.0
1.2
14.17
9.60
mm/h
—
6
53
32
290
1.11
0.18
1.1
1.2
—
—
—
0
0
1026
10201
1.04
0.18
6.0
5.6
2.69
2.76
mmol/l
1.57
965
9552
5
67
0.75
0.17
1.0
1.3
—
—
—
0
0
8
71
1.13
0.16
1.4
1.9
—
—
—
0
0
56
526
1.07
0.15
3.3
2.2
11.31
12.02
nmol/l
0.28
51
486
952
9571
0.97
0.13
4.5
4.1
1.31
1.26
mmol/l
1.25
884
8842
19
209
0.91
0.11
6.1
9.3
104.32
105.35
mmol/l
0.47
19
190
447
4420
1.02
0.10
2.1
1.9
1.39
1.33
mmol/l
0.81
368
3798
1000
10038
0.98
0.10
5.2
4.9
1.47
1.52
mmol/l
2.75
938
9379
5
47
1.06
0.09
1.0
2.2
—
—
—
0
0
63
606
1.04
0.09
1.1
1.0
—
—
—
0
0
6
57
1.05
0.08
1.3
1.2
33.52
32.61
nmol/l
—
6
49
872
8680
1.02
0.08
30.6
19.1
329.91
331.72
g/l
6.86
865
8625
46
441
1.04
0.07
3.0
1.8
3.99
3.67
mg/l
0.12
37
325
47
451
1.04
0.07
1.5
1.4
—
—
—
0
0
8
77
1.04
0.07
15.4
13.1
0.56
0.63
mmol/l
—
8
69
21
196
1.07
0.07
1.3
1.5
—
—
—
0
0
1010
10073
1.02
0.06
5.3
5.0
4.63
4.72
mmol/l
2.28
947
9465
47
453
1.04
0.06
1.5
1.5
0.30
0.32
mg/l
0.10
18
186
21
221
0.95
0.04
1.7
1.4
0.21
0.38
nmol/l
2.00
14
186
12
118
1.02
0.00
1.6
1.9
90.11
90.47
%
0.11
12
118
91
911
1.00
0.00
3.0
3.1
0.90
0.71
ug/l
0.79
55
565
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
11.00
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
2.83
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
1.4
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
2.18
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_ERYTHEMANODOSUM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ERYTHEMANODOSUM | 1.225 [1.06, 1.41] | 0.005 |
| Birth year | 0.99 [0.98, 1.0] | 0.027 |
During the follow-up period (1.1.1998 — 31.12.2019), 380 out of 3301 females with L12_ERYTHEMANODOSUM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ERYTHEMANODOSUM | 1.581 [1.26, 1.98] | < 0.001 |
| Birth year | 0.984 [0.97, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 148 out of 1122 males with L12_ERYTHEMANODOSUM died.
Mortality risk
Mortality risk for people of age
years, who have L12_ERYTHEMANODOSUM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.106% | 0.252% |
| 5 | 0.531% | 1.652% |
| 10 | 1.452% | 4.087% |
| 15 | 2.738% | 7.634% |
| 20 | 5.092% | 12.892% |
Relationships between endpoints
↥Index endpoint: L12_ERYTHEMANODOSUM – Erythema nodosum
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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