Melanocytic naevi of other and unspecified parts of face

CD2_BENIGN_MELANOCYTIC_FACE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.3&
  • Hospital discharge: ICD-9 2163A
  • Cause of death: ICD-10 D22.3&
  • Cause of death: ICD-9 2163A

2 out of 7 registries used, show all original rules.

2707

4. Check minimum number of events

None

2707

5. Include endpoints

None

2707

6. Filter based on genotype QC (FinnGen only)

2451

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) faciei

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 16215 10654 5504
Only index persons 15389 10225 5164
Unadjusted period prevalence (%)
Whole population 0.25 0.31 0.15
Only index persons 0.32 0.38 0.20
Median age at first event (years)
Whole population 44.36 44.13 44.75
Only index persons 44.23 43.97 44.75

-FinnGen-

Key figures

All Female Male
Number of individuals 2451 1725 726
Unadjusted period prevalence (%) 0.53 0.61 0.33
Median age at first event (years) 49.38 46.20 56.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2536
Matched controls
25360
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
5338.6
307.7
2456
145
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
17.6
307.7
1066
1005
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.6
245.5
548
1193
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
8.8
130.4
168
202
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
8.8
129.9
168
203
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
6.7
115.0
190
303
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
3.9
101.4
325
912
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.2
96.2
279
727
2163A
ICD-9 Finland
Benign neoplasm of skin, Skin of other and unspecified parts of face[KASVOJEN IHON BEN KASVAIN,NAEVUS PIGMENTOSUS]
+∞
88.0
84
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.7
82.3
285
839
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.6
81.7
298
908
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.4
81.6
751
3765
L57.0
ICD-10 Finland
Actinic keratosis
3.2
80.8
364
1266
L82
ICD-10 Finland
Seborrhoeic keratosis
2.5
79.9
630
2940
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.6
68.9
243
722
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.5
62.1
123
233
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
27.1
58.3
40
15
QAE00
NOMESCO Finland
Excision of loose skin or fold of skin from head and neck
17.7
57.6
47
27
TQW99
NOMESCO Finland
Other minor procedure on skin
3.7
57.4
195
564
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
5.3
52.4
108
212
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
8.5
49.4
64
77
XQ845
NOMESCO Finland
Dermatoscopy
5.4
47.9
95
180
S82
ICPC
Naevus/mole
2.2
47.2
475
2407
9733
FHL
Excision of skin change in operating room or anesthesia
6.4
44.6
75
121
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
4.2
40.4
109
267
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.7
40.3
94
205
XQ848
NOMESCO Finland
Dermatological photography
3.8
38.4
120
327
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
5.4
38.0
76
145
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
3.6
35.8
120
343
ZZR00
NOMESCO Finland
Flap of skin
4.5
34.9
86
196
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.7
34.5
190
728
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.4
33.0
120
362
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
4.6
32.5
77
170
DHB00
NOMESCO Finland
Excision of lesion of external nose
6.6
32.4
52
80
S18
ICPC
Laceration/cut
1.6
31.5
1181
8812
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
4.5
31.4
77
175
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.8
30.4
95
259
ZXC50
NOMESCO Finland
Cryotherapy
3.4
26.5
95
284
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
9.8
25.9
30
31
Z2221
NOMESCO Finland
Medical doctor
1.6
25.5
704
4808
D22
ICD-10 Finland
Melanocytic naevi
2.4
25.4
191
848
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.5
25.2
86
249
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
6.7
24.7
39
59
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
5.9
23.5
42
72
SPAT1153
SPAT
Removal of sutures
1.6
22.8
725
5099
I78.1
ICD-10 Finland
Naevus, non-neoplastic
3.5
22.4
79
234
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
3.9
21.6
64
168
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
3.8
20.3
63
171
C43.30
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face without histology
26.2
19.1
26
10
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
33.1
18.0
23
7
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
17.8
868
6621
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
3.7
17.1
53
144
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
17.0
554
3877
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
5.6
16.5
31
56
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
6.1
16.4
28
46
S21
ICPC
Skin texture symptom/complaint
1.6
16.2
380
2460
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
4.8
15.4
34
71
DAB00
NOMESCO Finland
Excision of lesion of auricle
4.9
14.7
32
66
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
3.8
14.7
44
117
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
3.9
14.5
42
109
L72.1
ICD-10 Finland
Trichilemmal cyst
1.9
14.2
175
938
J01DB01
ATC
cefalexin; oral
1.5
14.2
2032
18498
ZXA05
NOMESCO Finland
Left side
1.5
14.1
510
3636
F16
ICPC
Eyelid symptom/complaint
2.0
14.1
145
730
Z94.0
ICD-10 Finland
Kidney transplant status
4.4
14.0
35
81
D22.1
ICD-10 Finland
Melanocytic naevi of eyelid, including canthus
5.9
14.0
25
43
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
13.7
907
7231
127
Kela drug reimbursment
Transplant complication
3.7
13.6
43
119
Z71.8
ICD-10 Finland
Other specified counselling
1.4
13.5
857
6775
S77
ICPC
Malignant neoplasm of skin
4.2
13.4
35
84
D23.9
ICD-10 Finland
Benign neoplasm: Skin, unspecified
2.6
13.0
73
283
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
13.0
626
4711
C43.32
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face 'superficial spreading' type
22.6
12.9
18
8
ZXA00
NOMESCO Finland
Right side
1.5
12.8
547
4020
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
12.6
781
6135
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
15.5
12.6
20
13
ZXE00
NOMESCO Finland
One hour or less
1.4
12.5
887
7123
L04AA01
ATC
[U] ciclosporin
3.6
12.3
40
113
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
12.0
591
4452
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
11.9
226
1380
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.5
11.7
72
292
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
11.6
732
5753
S29
ICPC
Skin symptom/complaint other
1.5
11.3
478
3501
B03XA01
ATC
erythropoietin; parenteral
4.8
11.2
25
53
L01BC02
ATC
fluorouracil; systemic, topical
5.0
11.0
23
46
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.6
10.9
277
1821
D06BB10
ATC
imiquimod; topical
1.9
10.9
127
669
J02AC01
ATC
fluconazole; systemic
1.3
10.8
975
8078
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
4.0
10.8
30
76
D22.0
ICD-10 Finland
Melanocytic naevi of lip
9.6
10.7
21
22
CBA10
NOMESCO Finland
Biopsy of eyelid
3.9
10.6
30
77
D22.2
ICD-10 Finland
Melanocytic naevi of ear and external auricular canal
11.3
10.5
19
17
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
4.4
10.5
26
60
L91.0
ICD-10 Finland
Hypertrophic scar
3.1
10.5
43
141
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
10.2
812
6590
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
3.6
10.2
33
93
ZXC15
NOMESCO Finland
Use of photodynamic technique
3.5
10.2
34
98
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
4.1
10.2
27
66
EMB10
NOMESCO Finland
Tonsillectomy
1.8
10.1
149
846
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
7.9
10.1
22
28
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
4.8
10.0
22
46
ZXD20
NOMESCO Finland
Day surgery
1.5
10.0
286
1931
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
2.4
9.9
66
279
8720/3-C44.3
ICD-O-3
Malignant melanoma, NOS, of skin of other and unspecified parts of face
16.8
9.9
15
9
D17.0
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
2.9
9.9
45
157
UJF32
NOMESCO Finland
Coloscopy
1.4
9.8
540
4132
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
2.7
9.7
50
186
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
8.4
9.5
20
24
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
15.1
9.5
15
10
Z01.7
ICD-10 Finland
Laboratory examination
1.4
9.4
392
2853
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
9.4
263
1765
A98
ICPC
Health maint/preventive medicine
2.0
9.4
2445
23626
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
9.4
389
2831
E0000UV, ,
ATC
1.3
9.3
978
8227
D18.0
ICD-10 Finland
Haemangioma, any site
2.3
9.3
65
281
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
3.5
9.2
31
90
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
4.3
9.1
23
54
-59
ICPC
Other therap proced/minor surg NEC
2.4
9.1
61
259
A02BC05
ATC
esomeprazole; systemic
1.3
9.1
899
7497
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
9.0
363
2625
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
8.0
8.8
19
24
L04AA06
ATC
mycophenolic acid; systemic
2.7
8.8
45
167
Z3231
NOMESCO Finland
Registered nurse
1.4
8.8
573
4495
G04CA02
ATC
tamsulosin; oral
1.5
8.8
337
2415
ZXA10
NOMESCO Finland
Bilateral
1.4
8.8
380
2786
M54.5
ICD-10 Finland
Low back pain
1.3
8.7
870
7251
S04
ICPC
Lump/swelling localized
1.5
8.6
265
1815
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
8.6
299
2101
ZQZ00
NOMESCO Finland
Treatment of several skin areas
6.9
8.5
20
29
R42
ICD-10 Finland
Dizziness and giddiness
1.4
8.5
493
3794
Z01.2
ICD-10 Finland
Dental examination
1.3
8.5
1120
9671
M79.6
ICD-10 Finland
Pain in limb
1.3
8.4
1030
8805
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
8.4
534
4174
D03.30
ICD-10 Finland
Melanoma in situ on the lip
+∞
8.3
8
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
8.3
1739
15893
S08
ICPC
Skin colour change
1.8
8.3
119
672
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
10.8
8.3
15
14
K07.60
ICD-10 Finland
Snapping jaw
1.7
8.1
139
826
A02BC02
ATC
pantoprazole; systemic
1.3
8.1
1561
14091
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
8.1
1225
10737
L13
ICPC
Hip symptom/complaint
1.4
8.1
416
3140
J01FA10
ATC
azithromycin; systemic
1.3
8.0
1385
12330
ZXC20
NOMESCO Finland
Use of chemical agents
2.6
7.8
42
161
S59
ICPC
Skin, Other therap proced/minor surg NEC
2.3
7.8
58
259
I73.0
ICD-10 Finland
Raynaud syndrome
2.5
7.8
45
179
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.7
1748
16047
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
6.4
7.7
19
30
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.7
795
6634
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.1
7.5
20
49
-, ,
ICD-10 Finland
2.4
7.5
51
219
N02BE01
ATC
paracetamol; systemic, rectal
1.4
7.4
2159
20445
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
7.3
599
4841
TQW40, ,
SPAT
1.5
7.3
222
1517
I49.1
ICD-10 Finland
Atrial premature depolarization
2.0
7.3
81
421
WX402
NOMESCO Finland
General anaesthesia
1.3
7.3
496
3906
9734
FHL
Excision and local plastic or associated free skin grafting
4.2
7.3
19
46
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.9
7.2
85
451
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
7.2
659
5407
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.1
839
7105
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
7.1
140
867
J20
ICD-10 Finland
Acute bronchitis
1.5
7.0
230
1599
SCA01
NOMESCO Finland
Preventive oral health care, short
1.3
7.0
678
5601
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
3.4
7.0
24
71
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
3.3
7.0
25
76
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
7.0
629
5148
D07AC01
ATC
betamethasone; topical
1.3
7.0
792
6673
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.0
226
1567
J01EA01
ATC
trimethoprim; systemic
1.3
6.9
573
4634
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
6.9
475
3742
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.0
6.9
70
354
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
2.0
6.8
75
389
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
6.8
579
4700
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.8
908
7793
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.5
6.8
42
173
N02AX02
ATC
tramadol; systemic, rectal
1.3
6.8
898
7701
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
3.6
6.7
21
58
T78.4
ICD-10 Finland
Allergy, unspecified
1.7
6.7
109
640
J01FA09
ATC
clarithromycin; systemic
1.3
6.7
690
5737
R4110
NOMESCO Finland
Physiotherapy
1.3
6.7
576
4682
TQW80
NOMESCO Finland
Local dermatologic skincare
2.1
6.7
57
270
J39.9
ICD-10 Finland
Disease of upper respiratory tract, unspecified
4.0
6.6
18
45
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
5.5
6.6
18
33
J35.0
ICD-10 Finland
Chronic tonsillitis
1.6
6.6
130
805
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.3
6.6
512
4106
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.6
6.5
36
140
J05AB11
ATC
valaciclovir; oral
1.4
6.5
322
2414
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
5.7
6.4
17
30
J01DA01
ATC
[U] cefalexin
1.2
6.4
1392
12571
A12AA04
ATC
calcium carbonate; oral
2.7
6.4
33
124
A02BC03
ATC
lansoprazole; oral
1.3
6.4
574
4687
WX002
NOMESCO Finland
Sedation and analgesia
1.3
6.4
380
2929
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.4
6.4
41
172
N63
ICD-10 Finland
Unspecified lump in breast
1.6
6.3
160
1053
H00.1
ICD-10 Finland
Chalazion
1.8
6.3
91
517
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
6.0
6.3
16
27
J01AA02
ATC
doxycycline; systemic
1.3
6.3
1778
16514
QAE15
NOMESCO Finland
Excision of other superficial lesion of skin from head and neck
11.0
6.3
11
10
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
9.3
6.3
12
13
N76.0
ICD-10 Finland
Acute vaginitis
1.5
6.2
175
1177
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.5
6.2
176
1186
R01AD09
ATC
mometasone; nasal
1.2
6.2
1060
9320
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
1.4
6.1
240
1725
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.1
1621
14922
D06BX02
ATC
ingenol mebutate; topical
3.0
6.1
26
88
R60.0
ICD-10 Finland
Localized oedema
1.4
6.1
245
1770
PAW37
NOMESCO Finland
Biopsy of temporal artery
4.1
6.1
16
39
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
2.7
6.0
30
111
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
5.2
6.0
17
33

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1420
9145
2.26
85.75
2.8
2.1
—
—
—
0
0
516
2974
1.92
35.01
1.5
1.3
—
—
—
0
0
2067
18845
1.52
14.74
21.9
18.9
331.97
332.12
g/l
0.31
2054
18742
2231
20787
1.61
13.41
5.2
4.8
5.78
5.82
mmol/l
0.81
2107
19308
1372
11741
1.37
13.15
6.7
6.3
0.04
0.04
e9/l
0.93
1192
10184
1368
11717
1.36
12.95
6.7
6.3
0.55
0.56
e9/l
1.20
1189
10164
2320
21904
1.69
12.31
16.3
14.9
22.05
22.40
mg/l
0.20
1920
18044
1402
12108
1.35
12.29
7.0
6.6
0.19
0.19
e9/l
0.09
1239
10670
1158
9744
1.35
11.91
5.2
4.9
36.65
36.08
g/l
3.42
1090
9188
852
6865
1.36
11.53
6.4
6.1
—
—
—
0
0
1858
16852
1.38
11.41
9.0
8.0
76.78
77.33
u/l
0.20
1775
16066
721
5675
1.38
11.25
4.5
4.0
92.08
92.12
%
0.02
705
5545
1381
12000
1.33
11.10
6.8
6.4
2.00
1.93
e9/l
0.57
1229
10673
2304
21803
1.62
11.00
6.0
5.4
2.74
2.75
mmol/l
0.25
2210
20516
1488
13081
1.33
10.97
10.0
9.5
3.86
4.05
e9/l
2.95
1295
11429
1833
16628
1.37
10.95
4.7
4.3
10.58
11.33
mm/h
1.68
1737
15640
2318
21972
1.64
10.94
18.6
16.9
139.73
139.64
mmol/l
1.03
2281
21560
2402
23002
1.84
10.74
13.0
11.6
25.77
25.42
u/l
0.37
2355
22464
2320
22018
1.63
10.61
18.9
17.0
3.93
3.95
mmol/l
2.49
2280
21559
872
7145
1.34
10.29
3.6
3.3
30.40
81.66
e6/l
2.53
666
5391
166
972
1.76
10.19
1.2
1.2
—
—
—
0
0
2409
23130
1.83
10.09
20.9
18.7
74.13
73.74
umol/l
0.27
2387
22895
2468
23894
2.23
10.04
25.5
22.7
90.63
90.81
fl
1.16
2451
23696
2468
23896
2.22
10.01
25.5
22.7
30.17
30.22
pg
0.83
2451
23697
2468
23896
2.22
10.01
26.1
23.2
40.36
40.36
%
0.02
2450
23686
2468
23897
2.22
9.99
25.6
22.7
4.50
4.48
e12/l
1.53
2424
23443
2161
20248
1.45
9.98
6.4
5.9
38.14
38.58
mmol/mol
1.82
2075
19126
2468
23902
2.21
9.90
25.6
22.8
6.66
6.72
e9/l
0.51
2425
23440
2468
23905
2.21
9.85
25.8
22.9
135.03
134.53
g/l
1.10
2449
23709
2276
21571
1.54
9.70
5.2
4.8
4.68
4.69
mmol/l
0.29
2180
20375
1124
9606
1.31
9.63
2.2
2.1
102.02
96.91
pmol/l
2.98
589
5093
2266
21462
1.52
9.62
5.0
4.7
1.49
1.49
mmol/l
0.03
2155
20156
373
2684
1.46
9.54
1.5
1.7
—
—
—
0
0
997
8393
1.31
9.52
4.4
3.9
55.19
94.47
e6/l
1.99
695
5752
2465
23891
2.13
9.38
25.6
22.8
257.32
256.95
e9/l
0.11
2430
23495
532
4092
1.38
9.32
3.5
3.7
221.86
437.57
ng/l
1.03
373
2922
2199
20770
1.44
8.78
6.6
5.6
1.81
1.86
mu/l
0.55
2104
19515
816
6741
1.31
8.76
3.1
2.9
0.20
0.03
—
10
129
755
6182
1.32
8.62
3.4
3.1
0.37
0.40
e6/l
0.16
545
4475
1235
10786
1.28
8.59
7.0
6.5
0.68
0.68
%
0.07
1169
10137
499
3845
1.37
8.57
3.0
2.8
1.81
1.08
e6/l
0.33
261
1984
1233
10782
1.28
8.43
6.9
6.4
2.84
2.80
%
0.26
1167
10143
1234
10799
1.28
8.36
7.0
6.5
8.61
8.63
%
0.06
1168
10170
360
2635
1.43
8.36
3.2
2.7
8.28
7.24
umol/l
0.34
309
2309
553
4358
1.34
8.18
2.8
2.8
2.44
2.44
mmol/l
0.50
481
3930
460
3536
1.37
7.97
3.1
2.9
3.71
3.01
e6/l
0.54
222
1674
2008
18765
1.34
7.89
20.8
18.3
13.45
13.53
%
2.26
1991
18532
1375
12290
1.26
7.44
4.3
3.8
0.00
0.13
estimate
0.56
234
2450
1935
18034
1.31
7.42
5.4
4.6
14.59
14.64
pmol/l
0.46
1830
16782
369
2767
1.39
7.42
1.5
1.4
—
—
—
0
0
688
5664
1.29
7.34
2.9
2.6
330.06
329.60
umol/l
0.04
617
5055
1253
11105
1.25
7.20
6.8
6.4
29.11
28.35
%
1.77
1195
10572
303
2211
1.42
7.12
2.7
2.4
34.08
59.75
u/l
0.62
249
1874
242
1693
1.47
7.12
4.8
3.7
84.96
83.90
ng/l
0.08
222
1480
1622
14830
1.26
7.01
5.2
4.6
1546.87
1789.75
e6/l
0.07
16
197
1297
11565
1.25
6.97
6.9
6.3
11.06
11.06
umol/l
0.00
1232
11041
1318
11793
1.24
6.80
3.7
3.2
97.31
101.69
ug/l
0.21
1260
11117
2148
20386
1.35
6.77
4.3
4.1
1.24
1.26
mmol/l
0.79
2023
18992
1358
12207
1.24
6.65
4.2
3.8
0.00
4.27
estimate
2.07
244
2578
26
84
3.12
6.59
39.5
28.2
85.06
122.52
ug/l
4.78
26
71
1228
10927
1.24
6.57
6.8
6.3
56.28
57.00
%
1.52
1182
10470
1058
9293
1.24
6.29
2.0
1.9
1.36
1.35
mmol/l
0.12
950
7964
702
5920
1.26
5.95
3.4
3.1
—
0.00
estimate
—
0
18
660
5527
1.26
5.94
4.4
3.7
2.40
0.24
—
5
51
809
6940
1.24
5.88
3.3
3.1
—
—
—
0
0
1335
12072
1.22
5.85
4.2
3.8
0.00
0.00
estimate
0.37
240
2531
1186
10608
1.22
5.75
2.7
2.5
77.03
76.57
nmol/l
0.23
1107
9756
770
6588
1.24
5.70
5.3
4.0
7.40
7.40
ph
0.50
563
4715
415
3295
1.31
5.66
2.4
2.5
85.50
117.25
ug/g
3.26
334
2637
226
1640
1.42
5.49
3.9
3.5
4.50
4.53
pmol/l
0.21
203
1473
890
7760
1.23
5.47
3.5
3.4
2.36
2.35
mmol/l
0.22
810
7116
591
4931
1.26
5.43
3.0
2.6
5.05
6.84
e6/l
2.26
543
4465
1097
9787
1.21
5.31
3.9
3.4
6.26
6.24
ph
0.28
612
5581
537
4448
1.26
5.23
6.1
5.3
2.32
2.53
ug/l
0.29
482
4009
846
7380
1.22
5.09
3.5
3.4
7.63
7.49
mmol/l
0.35
749
6339
342
2683
1.32
5.07
3.3
3.1
0.73
0.75
ug/l
0.10
216
1685
1206
10923
1.20
4.81
7.9
6.9
1.22
1.21
mmol/l
1.26
1088
9496
327
2575
1.31
4.72
1.4
1.4
—
—
—
0
0
233
1756
1.36
4.54
2.6
2.4
0.21
0.49
e6/l
2.30
218
1666
254
1942
1.34
4.51
1.4
1.2
108.51
143.45
u/ml
1.06
110
742
774
6761
1.21
4.48
4.1
4.1
11.08
8.45
mg/mmol
0.47
477
4196
1183
10746
1.19
4.44
3.0
2.8
—
—
estimate
—
0
0
887
7857
1.20
4.41
3.7
3.2
30.53
32.13
u/l
0.58
847
7465
760
6646
1.20
4.32
3.6
3.5
52.84
47.20
mg/l
0.24
493
4182
1400
12941
1.18
4.18
5.0
4.9
6.48
6.56
mmol/l
0.64
1308
12179
19
68
2.81
4.12
2.0
2.7
0.61
0.62
mmol/l
0.11
19
68
100
658
1.54
4.05
1.2
1.2
—
—
—
0
0
751
6605
1.19
3.95
2.1
2.2
144.55
196.75
u/l
2.17
719
6286
29
131
2.23
3.93
2.1
1.5
121.32
90.78
ng/l
0.58
29
131
1075
9756
1.18
3.91
7.2
6.3
1.21
1.21
mmol/l
0.32
1017
9060
347
2824
1.27
3.88
6.5
5.7
1.06
1.04
mmol/l
0.44
326
2621
96
634
1.53
3.84
3.9
3.3
1.49
1.48
mg/l
0.01
90
580
1663
15653
1.18
3.82
3.4
3.2
47.26
43.14
u/l
0.69
1589
14868
624
5415
1.20
3.78
4.6
3.9
1.02
1.57
kg/l
0.80
426
3617
149
1085
1.40
3.63
2.5
2.3
—
—
—
0
0
187
1413
1.35
3.63
2.4
3.3
75.97
58.28
u/ml
0.24
180
1367
190
1440
1.35
3.61
2.6
2.3
11.87
12.26
nmol/l
0.24
182
1307
114
796
1.45
3.51
1.2
1.2
—
—
—
0
0
697
6158
1.18
3.41
1.8
1.7
20.10
20.49
nmol/l
0.32
618
5274
379
3167
1.23
3.35
1.2
1.2
—
—
—
0
0
99
685
1.46
3.22
2.3
2.6
—
—
—
0
0
133
972
1.39
3.21
1.4
1.3
226.30
227.36
miu/ml
0.01
61
472
159
1207
1.34
3.03
1.1
1.1
—
—
—
0
0
68
441
1.56
3.02
1.3
1.4
2.74
3.94
ug/l
1.06
56
403
535
4668
1.19
3.00
1.4
1.3
30.58
28.64
iu/ml
0.08
149
1403
284
2331
1.25
2.97
2.9
2.8
1.69
1.81
%
1.61
257
2096
1036
9520
1.15
2.95
12.3
13.3
1.18
1.21
inr
1.09
861
7930
267
2178
1.25
2.95
2.4
2.0
0.00
0.02
estimate
1.06
55
466
103
732
1.42
2.94
2.1
2.2
27.08
11.25
iu/l
0.27
37
319
422
3611
1.20
2.94
3.4
3.3
0.82
0.82
mmol/l
0.16
403
3417
54
334
1.63
2.92
1.6
1.6
347.22
342.83
mu/l
0.05
46
268
71
469
1.53
2.92
1.1
1.1
23.02
19.68
au/ml
0.12
21
125
1101
10166
1.15
2.92
10.7
10.9
0.00
0.00
e9/l
0.19
884
8314
154
1174
1.33
2.87
7.6
11.0
16.19
15.99
%
0.45
149
1132
199
1572
1.29
2.87
1.3
1.4
23.15
26.77
iu/l
0.90
176
1334
407
3482
1.20
2.84
1.5
1.4
736.00
485.06
titre
0.93
90
727
106
767
1.40
2.75
1.5
1.4
8.30
11.09
u/l
2.01
86
617
43
256
1.69
2.71
1.6
1.6
—
—
—
0
0
62
405
1.54
2.70
1.2
1.2
—
—
—
0
0
659
5904
1.16
2.62
1.4
1.3
0.83
1.42
u/ml
2.32
155
1631
32
177
1.82
2.60
1.2
1.2
—
—
—
0
0
241
1977
1.24
2.56
7.1
9.0
123.14
121.23
g/l
0.84
236
1936
27
143
1.90
2.51
7.6
7.3
1.60
144.72
ug/l
0.66
16
93
494
4346
1.17
2.49
1.4
1.3
6.23
10.00
u/ml
0.81
181
1722
433
3771
1.18
2.47
3.0
2.5
58.89
13.46
umol/l
0.49
415
3520
217
1767
1.25
2.47
2.8
2.7
68.43
70.82
e9/l
0.44
154
1285
404
3499
1.18
2.46
2.9
2.5
2.38
2.36
g/l
0.25
382
3244
40
242
1.66
2.41
6.3
5.1
291.56
76.22
u/ml
0.56
14
72
187
1503
1.26
2.39
2.8
2.9
100.12
181.30
ng/l
7.56
169
1364
774
7056
1.14
2.37
2.8
2.6
59.00
70.99
u/l
0.49
725
6571
377
3258
1.18
2.36
2.7
2.1
29.81
29.28
s
0.81
365
3160
62
420
1.49
2.33
4.8
8.6
10.75
11.37
mmol/l
0.87
55
383
567
5066
1.15
2.32
1.6
1.5
2.08
2.31
g/l
2.68
344
3214
32
184
1.75
2.32
1.0
1.1
2.51
8.60
iu/ml
2.68
11
53
25
447
0.55
2.31
3.7
3.7
41.61
24.75
mg/l
0.64
17
307
62
421
1.48
2.30
4.8
8.6
105.18
105.23
mmol/l
0.03
55
384
584
5236
1.15
2.28
2.1
1.8
1.08
1.07
mg/l
0.00
459
4028
197
1604
1.25
2.26
1.3
1.2
—
—
—
0
0
27
149
1.82
2.24
2.6
2.5
163.71
215.92
e6/l
1.15
21
128
86
625
1.39
2.23
4.3
7.0
1.13
1.29
mmol/l
1.09
76
547
81
583
1.40
2.23
2.6
3.2
3.44
2.33
index
0.45
39
305
129
999
1.31
2.22
1.4
1.3
1.11
0.99
u/ml
0.04
14
70
20
102
1.97
2.10
3.2
2.9
—
—
—
0
0
37
229
1.62
2.08
1.1
1.1
—
—
—
0
0
476
4236
1.15
2.06
2.9
2.8
525.57
523.56
mosm/kgh2o
0.07
426
3707
98
741
1.34
2.02
2.2
1.7
0.23
0.23
g/l
0.45
93
705
199
1650
1.22
1.96
2.4
2.4
32.95
19.91
au/ml
0.94
20
194
42
273
1.55
1.95
2.3
2.3
—
—
—
0
0
242
2047
1.20
1.95
1.2
1.2
—
—
—
0
0
277
2374
1.19
1.93
6.6
8.2
7.42
7.41
ph
0.51
147
1314
216
1810
1.21
1.92
8.3
7.4
10.05
9.19
mmol/l
0.85
199
1747
137
1705
0.79
1.92
3.2
3.5
1.23
1.23
mmol/l
0.17
116
1466
248
2107
1.20
1.91
3.6
4.2
24.53
18.91
ug/l
0.11
188
1676
211
2504
0.83
1.88
4.7
4.6
33.38
32.51
%
0.55
142
1738
274
2357
1.18
1.84
6.6
8.2
0.76
0.89
mmol/l
0.20
214
1925
13
59
2.21
1.84
1.2
1.3
8.39
7.81
mmol/l
0.10
13
59
19
337
0.56
1.77
7.9
6.0
370.26
363.97
umol/l
0.09
19
298
36
232
1.56
1.76
3.4
3.3
2.33
28.34
nmol/l
0.57
36
226
38
248
1.54
1.76
1.5
2.4
0.82
1.07
g/24h
0.44
23
144
161
1323
1.23
1.76
2.2
2.2
3875.52
6687.37
u/l
0.67
64
546
361
3189
1.15
1.74
3.2
2.5
22.31
22.93
%
0.43
344
2978
28
170
1.65
1.73
2.4
3.1
17.21
36.33
mg/l
0.70
22
122
20
110
1.82
1.73
2.3
2.7
18.11
91.81
ug/l
0.51
20
97
275
2382
1.17
1.71
6.6
8.2
5.12
5.09
kpa
0.22
265
2294
584
5332
1.12
1.70
2.2
2.0
—
—
—
0
0
182
1522
1.21
1.68
1.3
1.3
59.11
48.91
au/ml
—
9
97
658
6055
1.12
1.67
2.5
2.3
2.60
2.74
mg/l
0.66
588
5264
214
1822
1.19
1.64
9.2
9.0
—
—
—
0
0
274
2383
1.17
1.63
6.6
8.2
12.60
12.65
kpa
0.06
264
2294
220
1880
1.19
1.62
2.7
2.5
6.04
6.14
ph
0.67
141
1265
193
1632
1.20
1.60
2.0
2.3
4.76
6.94
ug/l
1.75
166
1444
798
7443
1.11
1.56
2.6
2.4
—
—
—
0
0
203
1729
1.19
1.56
1.3
1.3
150.20
238.37
u/ml
0.91
195
1599
621
5717
1.11
1.56
4.2
4.3
—
—
—
0
0
17
92
1.85
1.56
3.5
3.0
—
—
—
0
0
595
5466
1.12
1.55
4.1
4.6
—
—
—
0
0
12
57
2.11
1.55
1.0
1.1
15.34
37.39
iu/ml
1.81
12
57
24
145
1.66
1.54
2.6
2.5
494.00
543.18
e6/l
0.17
17
118
14
71
1.98
1.54
1.4
1.2
—
—
—
0
0
25
153
1.64
1.53
1.4
1.5
81.36
77.24
umol/l
0.41
25
153
28
177
1.59
1.51
1.1
1.1
—
—
—
0
0
65
486
1.35
1.51
1.6
1.4
—
—
—
0
0
55
744
0.73
1.49
1.6
1.5
—
—
—
0
0
243
2111
1.17
1.49
6.9
8.7
95.77
95.71
%
0.05
232
2050
13
65
2.01
1.48
1.5
2.0
0.15
0.15
e9/l
—
5
29
50
680
0.73
1.41
3.5
3.4
7.41
7.41
ph
0.03
50
674
9
40
2.25
1.40
1.2
1.7
—
—
—
0
0
19
313
0.60
1.40
1.9
1.8
1.62
1.67
mmol/l
0.14
19
308
221
1917
1.17
1.39
1.3
1.4
—
—
—
0
0
67
511
1.32
1.38
1.1
1.1
1.59
1.72
u/ml
0.04
37
259
24
150
1.61
1.38
1.0
1.0
—
—
—
0
0
30
198
1.52
1.37
1.2
1.1
105.27
112.40
pmol/l
0.51
30
198
157
1325
1.20
1.36
1.4
1.2
—
—
—
0
0
79
618
1.29
1.36
2.0
2.2
11.62
11.79
mg/l
0.07
74
581
55
732
0.75
1.36
1.6
1.5
1.24
1.26
mm
0.12
40
532
45
324
1.40
1.34
1.7
1.5
22.32
65.91
mu/l
1.77
39
294
9
42
2.15
1.33
1.2
1.0
—
—
—
0
0
9
42
2.15
1.33
1.2
1.0
—
—
—
0
0
9
42
2.15
1.33
1.2
1.0
—
—
—
0
0
9
42
2.15
1.33
1.8
1.1
5.56
5.56
nmol/l
—
9
42
971
9200
1.09
1.33
4.0
3.7
0.05
0.10
estimate
0.39
190
2090
52
385
1.36
1.32
1.2
1.2
—
—
—
0
0
76
595
1.29
1.31
1.3
1.3
—
8.13
—
0
12
26
168
1.55
1.31
1.3
1.4
—
—
—
0
0
42
300
1.41
1.31
1.5
1.4
295.19
323.50
pmol/l
0.31
37
258
606
5622
1.10
1.31
2.6
2.3
—
—
—
0
0
28
415
0.67
1.30
3.0
2.5
16.81
16.42
%
0.34
28
407
49
360
1.37
1.30
1.2
1.2
—
—
—
0
0
68
527
1.30
1.27
1.2
1.1
0.75
1.24
u/ml
0.42
38
224
93
750
1.25
1.27
3.0
3.7
532.15
5393.93
u/ml
0.74
76
653
261
2315
1.14
1.23
2.4
2.2
393.29
382.19
nmol/l
0.45
244
2153
46
338
1.37
1.23
1.3
1.3
—
0.39
nmol/l
—
0
19
55
715
0.76
1.19
4.5
4.0
24.45
24.89
mmol/l
0.81
50
661
8
38
2.11
1.18
1.1
1.7
—
—
—
0
0
69
543
1.28
1.17
1.2
1.1
5.81
4.93
u/ml
0.19
48
294
415
4523
0.90
1.17
1.6
1.7
429.71
30836171.50
pmol/l
3.92
360
3817
29
198
1.47
1.17
1.1
1.1
11.44
15.47
u/ml
0.83
12
91
347
3151
1.12
1.14
2.1
2.0
—
—
—
0
0
73
582
1.26
1.13
1.1
1.1
—
—
—
0
0
28
192
1.46
1.11
2.3
2.5
16.92
28.43
mg/l
1.63
18
138
15
88
1.71
1.11
1.7
2.1
6.07
9.81
%
1.07
15
83
60
762
0.78
1.10
1.6
1.6
—
—
—
0
0
55
425
1.30
1.09
1.7
1.7
—
—
—
0
0
51
390
1.31
1.09
1.1
1.1
0.62
0.29
u/ml
0.31
17
121
101
840
1.21
1.07
4.0
5.8
0.85
0.89
%
0.54
95
794
111
932
1.20
1.07
1.8
1.6
20.05
11.58
u/ml
0.54
32
234
51
391
1.31
1.07
1.2
1.3
4.30
4.21
u/ml
0.03
23
174
30
211
1.43
1.06
1.2
1.1
—
—
—
0
0
350
3195
1.11
1.05
1.8
1.8
—
—
—
0
0
73
900
0.81
1.05
4.1
3.8
—
—
—
0
0
53
411
1.30
1.03
1.1
1.1
4.42
5.15
u/ml
0.10
26
185
13
75
1.74
1.02
3.5
3.3
—
—
—
0
0
79
645
1.23
1.01
3.8
3.8
139.21
61.20
mg/l
0.69
63
562
77
627
1.24
1.01
1.2
1.1
0.89
2.51
u/ml
2.64
44
329
29
205
1.42
1.00
2.5
2.4
1168.05
1256.19
e6/l
0.23
22
182
79
646
1.23
1.00
3.8
3.8
29.72
63.03
mg/l
1.10
63
564
38
282
1.35
1.00
1.3
1.3
—
—
nmol/l
—
0
0
31
223
1.39
0.98
1.4
1.4
7.71
8.36
mmol/l
0.38
31
215
109
923
1.19
0.98
2.8
1.9
1.30
1.53
g/l
2.21
95
815
0
29
0.00
0.97
0.0
2.2
—
3.04
—
0
12
128
1100
1.17
0.97
1.9
1.6
298.49
297.74
mu/l
0.01
119
997
20
132
1.52
0.97
1.8
1.4
10.95
12.95
u/l
0.88
20
125
57
451
1.27
0.97
1.6
1.4
155.00
148.55
au/ml
—
9
125
332
3038
1.11
0.97
1.9
1.6
—
—
—
0
0
626
5897
1.08
0.96
2.9
3.1
1091.09
1160.82
ng/l
0.16
510
5002
61
490
1.25
0.92
1.9
1.9
—
—
—
0
0
113
967
1.18
0.91
1.1
1.1
—
—
—
0
0
38
287
1.33
0.91
1.3
1.3
0.15
0.24
nmol/l
0.83
27
219
53
420
1.27
0.90
1.4
1.4
18.00
26.53
u/l
1.58
45
353
21
144
1.46
0.87
2.5
2.3
695.81
628.04
ml
0.44
16
98
20
136
1.47
0.86
2.9
2.8
43.60
43.37
%
—
10
73
52
414
1.26
0.86
1.3
1.1
—
—
—
0
0
11
64
1.72
0.86
5.3
4.2
—
—
—
0
0
107
918
1.17
0.85
3.8
5.6
1.64
1.57
%
0.31
101
870
8
45
1.78
0.84
1.4
1.3
—
—
—
0
0
27
196
1.38
0.84
1.1
1.1
—
—
—
0
0
81
960
0.84
0.83
1.5
1.5
66.28
59.02
ug/l
0.70
70
809
18
261
0.69
0.82
3.1
2.6
—
—
—
0
0
25
180
1.39
0.82
1.1
1.5
41.01
34.06
nmol/l
0.51
19
159
104
896
1.17
0.80
3.2
2.2
20.73
20.50
s
0.29
86
784
10
58
1.73
0.79
1.1
1.1
—
—
—
0
0
16
106
1.51
0.79
2.2
1.4
228.15
157.30
pmol/l
0.68
16
106
8
48
1.67
0.78
1.1
1.0
—
—
—
0
0
27
200
1.35
0.76
1.6
2.2
—
—
—
0
0
222
2020
1.11
0.76
4.9
3.6
1.48
1.84
mmol/l
0.98
197
1755
10
59
1.70
0.75
1.0
1.0
—
—
—
0
0
15
99
1.52
0.75
1.7
2.0
—
—
—
0
0
15
99
1.52
0.75
1.3
1.1
154.53
183.14
iu/ml
0.36
15
99
72
605
1.20
0.75
1.3
1.2
27.13
47.46
u/ml
—
8
54
148
1316
1.13
0.75
8.6
10.2
0.63
0.64
%
0.10
148
1308
180
1995
0.89
0.74
4.6
4.0
7.35
7.35
ph
0.05
130
1445
231
2110
1.10
0.73
1.7
1.7
3.34
3.46
mmol/l
0.91
169
1444
32
413
0.77
0.73
3.5
3.9
4.95
5.05
kpa
0.34
32
407
478
4507
1.07
0.73
1.8
1.7
—
—
—
0
0
32
412
0.77
0.72
3.5
3.9
2.84
2.55
mmol/l
0.20
19
277
32
412
0.77
0.72
3.5
3.9
8.89
8.68
kpa
0.31
32
406
11
68
1.62
0.71
1.2
1.4
—
—
—
0
0
9
57
1.58
0.71
1.0
1.1
—
—
—
0
0
31
238
1.31
0.70
1.5
1.3
—
—
—
0
0
80
684
1.18
0.70
1.1
1.1
3.25
5.10
eliau/ml
0.29
14
94
9
142
0.63
0.69
24.7
15.9
989.67
851.12
nmol/l
—
9
137
119
1051
1.14
0.68
2.4
1.9
4.99
7.47
iu/ml
1.03
33
250
5
27
1.85
0.68
9.0
11.6
5.26
5.88
mmol/l
—
5
27
228
2091
1.10
0.68
4.9
3.6
7.38
7.38
ph
0.22
139
1181
703
6732
1.06
0.68
3.2
3.2
0.05
0.18
estimate
0.51
182
2033
114
1290
0.88
0.68
3.8
3.7
7.42
7.42
ph
0.06
94
1093
226
2073
1.10
0.67
2.2
2.3
0.22
0.22
g/l
0.71
209
1948
53
439
1.21
0.66
1.1
1.1
2.01
4.00
u/ml
1.09
29
217
123
1092
1.13
0.66
2.2
2.1
0.03
0.72
estimate
0.49
38
355
158
1425
1.12
0.66
2.1
1.9
1.80
1.35
g/l
0.54
142
1317
44
358
1.23
0.65
2.4
1.9
—
8.14
—
0
7
24
180
1.34
0.65
1.1
1.2
—
—
—
0
0
56
667
0.84
0.64
3.2
3.6
1.31
1.37
mmol/l
0.18
56
658
8
129
0.62
0.63
1.6
2.3
7.76
8.13
mmol/l
—
8
129
41
332
1.24
0.63
2.0
1.6
—
—
—
0
0
124
1105
1.13
0.63
1.4
1.5
—
—
—
0
0
66
561
1.18
0.63
1.5
1.4
202.42
1311.32
e6/l
1.34
53
442
18
129
1.40
0.63
1.5
1.2
—
—
—
0
0
139
1248
1.12
0.63
5.2
7.0
24.52
24.38
mmol/l
0.17
134
1195
23
173
1.33
0.61
1.5
1.5
2098.00
1969.78
ml
0.26
23
168
65
554
1.18
0.61
1.5
1.4
20.70
47.29
e6/l
0.80
50
410
50
416
1.21
0.61
1.2
1.1
—
—
—
0
0
223
2057
1.09
0.61
1.7
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
173.56
—
0
9
0
22
0.00
0.59
0.0
1.4
—
5.93
—
0
12
151
1370
1.11
0.58
7.7
8.3
24.55
24.81
mmol/l
0.44
151
1363
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
6
35
1.72
0.57
1.3
1.3
55.50
65.86
ug/l
—
6
35
138
1249
1.11
0.56
8.8
10.0
24.03
24.22
mmol/l
0.35
133
1224
5
88
0.57
0.56
2.4
1.6
86.00
400.22
nmol/24h
—
5
88
323
3039
1.07
0.55
1.5
1.5
—
—
—
0
0
44
366
1.21
0.55
1.1
1.1
2.00
2.27
eliau/ml
0.15
23
175
14
194
0.72
0.54
1.1
1.1
—
—
—
0
0
12
82
1.47
0.54
3.1
2.9
—
—
—
0
0
149
1358
1.10
0.54
8.7
10.0
93.96
94.03
%
0.04
149
1351
66
573
1.16
0.52
3.9
3.6
13.46
2.89
ratio
0.64
34
328
55
639
0.86
0.51
1.3
1.3
—
—
—
0
0
120
1324
0.90
0.51
3.7
3.6
5.03
5.17
kpa
1.49
112
1273
47
398
1.18
0.50
2.0
1.5
0.86
0.72
g/l
0.25
39
310
14
189
0.74
0.48
1.5
1.4
13268.75
90238.03
e6/l
—
8
101
103
928
1.11
0.48
1.9
2.0
—
—
—
0
0
183
1697
1.08
0.47
3.3
2.8
67.00
66.70
g/l
0.23
174
1570
7
49
1.43
0.46
1.0
1.1
0.09
6.86
u/ml
—
7
41
118
1075
1.10
0.45
1.8
2.1
—
—
—
0
0
82
733
1.12
0.44
1.3
1.3
2.00
2.36
u/ml
—
6
67
37
438
0.84
0.44
4.2
3.6
—
—
—
0
0
12
86
1.40
0.44
1.4
1.6
12.39
14.19
pmol/l
0.78
12
71
223
2094
1.07
0.43
4.9
3.6
5.83
5.82
kpa
0.08
216
2040
9
129
0.70
0.43
1.2
1.1
—
10.40
—
0
15
58
660
0.88
0.43
15.0
9.2
—
—
—
0
0
14
185
0.76
0.43
1.1
1.5
1.67
1.11
promille
—
9
152
43
500
0.86
0.42
2.8
2.6
—
—
—
0
0
15
113
1.33
0.42
1.0
1.1
—
—
—
0
0
33
276
1.20
0.42
1.1
1.2
—
—
—
0
0
6
93
0.64
0.42
2.3
2.3
126.33
150.40
nmol/l
—
6
82
12
87
1.38
0.42
3.1
2.1
1.40
1.04
ug/l
0.35
12
82
23
185
1.25
0.41
1.1
1.2
—
—
—
0
0
22
272
0.81
0.41
1.5
2.0
0.85
0.90
%
0.21
15
181
59
668
0.88
0.41
1.4
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.05
—
0
6
0
16
0.00
0.41
0.0
1.1
—
1.16
—
0
9
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
174
1863
0.93
0.41
3.8
3.8
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
33.46
—
0
17
5
34
1.47
0.40
1.0
1.7
7.10
316005.28
nmol/l
—
5
25
20
159
1.26
0.40
1.4
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
14
107
1.31
0.37
2.4
1.3
146.71
164.66
mmol/24h
0.36
14
107
5
37
1.35
0.37
1.6
1.3
30.20
22.41
%
—
5
29
40
461
0.87
0.37
4.3
4.3
—
—
—
0
0
59
525
1.13
0.37
1.5
1.4
0.42
0.42
nmol/l
0.01
50
412
16
202
0.79
0.36
1.2
1.4
23578.00
122974.81
e6/l
—
9
134
9
70
1.29
0.36
1.6
1.9
—
—
—
0
0
72
649
1.11
0.36
1.1
1.2
—
—
—
0
0
48
545
0.88
0.36
3.4
3.8
3.90
3.86
mmol/l
0.33
48
539
81
736
1.10
0.35
1.3
1.3
2.54
8.11
u/ml
—
7
114
681
6626
1.04
0.35
4.6
3.9
0.01
0.00
estimate
0.22
225
2395
108
996
1.09
0.35
1.3
1.2
0.83
0.88
g/l
1.63
108
996
95
872
1.09
0.34
1.4
1.2
—
—
—
0
0
146
1365
1.07
0.34
8.8
9.9
1.29
1.32
%
0.13
146
1356
18
145
1.24
0.33
1.2
1.4
4.69
6.12
u/l
1.35
13
124
16
199
0.80
0.33
1.0
1.1
—
—
—
0
0
6
46
1.31
0.33
1.8
1.8
3.61
3.25
mmol/l
—
6
40
6
46
1.31
0.33
1.3
3.1
8.17
5.30
ug/l
—
6
46
29
247
1.18
0.32
1.3
1.3
—
—
—
0
0
18
220
0.82
0.32
1.6
1.4
1285.69
1929.73
e6/l
0.62
13
147
42
370
1.14
0.31
1.2
1.2
—
—
—
0
0
22
183
1.20
0.31
1.0
1.0
—
—
—
0
0
22
183
1.20
0.31
1.3
1.6
34.08
36.33
%
0.09
13
111
185
1952
0.94
0.31
3.7
4.3
0.47
0.67
%
0.75
55
543
354
3411
1.04
0.31
1.6
1.7
1100.84
1180.25
nmol/l
0.97
263
2622
56
505
1.11
0.30
1.5
1.2
218.03
250.69
u/ml
0.65
37
316
11
141
0.78
0.29
1.1
1.3
6.27
9.11
mm/h
1.09
11
141
38
335
1.14
0.29
1.6
1.4
6.76
7.17
mmol/l
0.46
33
297
8
108
0.74
0.29
1.6
2.5
1758.00
1935.94
ml
—
8
98
16
130
1.23
0.28
1.5
1.2
14.81
11.22
u/l
0.57
16
117
8
64
1.25
0.27
1.3
1.4
—
—
—
0
0
17
204
0.83
0.27
1.2
1.2
35.10
40.90
mg/l
0.31
17
174
188
1971
0.95
0.26
3.9
4.5
0.02
0.11
%
2.38
43
494
46
414
1.11
0.26
2.0
2.2
6.38
4.77
umol/l
0.54
39
301
902
9177
0.97
0.26
2.8
2.9
—
—
—
0
0
21
178
1.18
0.26
1.4
1.9
5.75
3.88
mg/l
0.51
21
172
99
926
1.07
0.25
1.8
1.9
—
—
—
0
0
23
197
1.17
0.25
1.3
1.1
70.00
156.22
titre
—
6
37
23
197
1.17
0.25
1.3
1.1
—
290.00
—
0
5
20
169
1.18
0.25
1.1
1.1
—
—
—
0
0
32
283
1.13
0.24
2.5
2.3
—
—
—
0
0
7
93
0.75
0.22
1.0
1.0
—
—
—
0
0
190
1824
1.05
0.22
2.9
2.9
10.35
10.71
g/l
0.46
176
1685
117
1109
1.06
0.22
4.1
2.7
1.26
1.26
%
0.00
117
1102
13
107
1.22
0.21
1.4
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
373.27
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
3.28
—
0
12
8
103
0.78
0.21
2.8
2.0
—
—
—
0
0
5
43
1.16
0.21
1.2
3.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
64.87
—
0
8
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
90
848
1.06
0.20
2.6
2.8
—
—
—
0
0
136
1424
0.95
0.20
1.8
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
0.16
—
0
14
0
14
0.00
0.20
0.0
1.5
—
20.00
—
0
9
183
1760
1.04
0.20
3.8
3.0
4.55
4.55
kpa
0.00
177
1713
191
1983
0.96
0.20
4.3
4.8
0.09
0.28
%
0.55
47
452
9
113
0.80
0.20
2.2
1.6
0.53
0.47
e9/l
—
9
113
60
558
1.08
0.19
1.4
1.7
22278.26
11058.82
e6/l
0.42
39
393
123
1173
1.05
0.19
1.8
2.0
—
—
—
0
0
59
633
0.93
0.19
1.3
1.3
—
—
—
0
0
16
137
1.17
0.18
1.1
1.1
1349.06
1576.15
miu/ml
0.42
16
137
73
686
1.07
0.18
1.3
1.2
84.55
90.31
titre
0.09
11
64
288
2801
1.03
0.18
2.0
1.9
3.37
3.42
ratio
0.25
219
2111
122
1166
1.05
0.18
1.8
2.0
—
—
—
0
0
17
195
0.87
0.17
1.1
1.1
246.76
250.11
mg/l
0.02
17
172
27
299
0.90
0.17
1.4
1.2
—
—
—
0
0
26
288
0.90
0.16
2.0
2.9
—
—
—
0
0
14
120
1.17
0.16
1.1
1.1
—
—
—
0
0
48
514
0.93
0.15
1.4
1.4
—
—
—
0
0
6
76
0.79
0.15
3.7
1.9
42.65
40.44
g/l
—
6
76
51
477
1.07
0.15
1.2
1.1
—
—
—
0
0
6
80
0.75
0.15
1.7
1.7
0.00
0.04
estimate
—
6
80
109
1045
1.04
0.15
2.0
1.9
—
—
—
0
0
51
478
1.07
0.15
1.2
1.1
—
—
—
0
0
120
1154
1.04
0.15
1.9
2.0
—
—
—
0
0
23
207
1.11
0.15
4.0
3.4
54.94
55.48
%
0.04
17
188
99
1033
0.96
0.14
1.6
1.7
0.27
0.33
mg/l
0.47
39
470
70
737
0.95
0.14
3.4
3.4
224.81
389.15
mg/l
0.99
37
312
101
969
1.04
0.14
1.2
1.1
1.54
1.56
g/l
0.33
101
969
28
256
1.09
0.14
1.3
1.5
—
—
—
0
0
10
84
1.19
0.14
1.6
2.0
30.80
28.96
%
—
10
84
47
441
1.07
0.13
2.8
2.4
46.60
90.32
ug/min
1.35
32
273
10
117
0.85
0.13
1.5
2.5
15.95
16.33
%
—
10
117
34
365
0.93
0.12
3.2
3.5
0.76
0.82
nmol/l
0.43
25
305
200
2050
0.97
0.12
3.8
4.5
0.81
0.96
%
0.30
55
574
23
210
1.10
0.12
2.3
3.2
14.23
12.53
index
0.19
13
129
12
137
0.88
0.12
1.2
1.4
149.77
133.84
nmol/l
0.93
12
137
10
116
0.86
0.12
1.0
1.2
—
—
—
0
0
54
513
1.05
0.11
3.1
3.3
55.96
58.11
%
0.68
54
513
14
157
0.89
0.11
1.1
1.2
0.61
0.60
ratio
—
9
93
94
909
1.04
0.10
1.1
1.1
0.46
0.63
ratio
1.99
13
112
291
2958
0.98
0.10
3.5
3.1
4.16
4.61
e9/l
1.01
253
2610
11
97
1.13
0.09
1.8
1.7
—
—
—
0
0
18
196
0.92
0.09
2.9
2.7
—
—
—
0
0
6
55
1.09
0.09
4.3
7.1
27.72
25.24
mmol/l
—
6
50
702
6962
1.01
0.08
1.6
1.6
—
—
—
0
0
6
57
1.05
0.08
1.0
1.1
—
—
—
0
0
32
302
1.06
0.08
1.6
1.4
—
—
—
0
0
32
302
1.06
0.08
1.6
1.4
—
—
—
0
0
32
302
1.06
0.08
1.6
1.4
—
—
—
0
0
32
302
1.06
0.08
1.6
1.4
—
—
—
0
0
5
64
0.78
0.08
1.6
2.3
16.34
17.56
umol/l
—
5
64
7
65
1.08
0.08
1.0
1.3
—
—
—
0
0
8
75
1.07
0.07
1.4
1.3
28.75
27.89
s
—
8
75
119
1164
1.02
0.07
1.9
2.0
—
—
—
0
0
24
255
0.94
0.07
1.4
1.7
61.50
58.31
%
0.11
12
164
30
316
0.95
0.07
3.8
3.7
1.76
1.38
%
0.29
25
290
47
452
1.04
0.07
3.1
2.3
0.74
0.88
nmol/l
1.21
40
382
112
1096
1.02
0.06
3.7
3.2
1.02
1.02
ratio
0.18
100
993
802
7976
1.01
0.06
3.5
3.6
21.61
60.70
ng/l
2.37
481
5150
23
218
1.06
0.05
1.3
1.2
—
—
—
0
0
166
1682
0.99
0.05
1.5
1.6
1022.07
1005.03
mu/l
0.08
143
1419
24
252
0.95
0.05
1.0
1.1
—
—
—
0
0
18
191
0.94
0.04
1.4
1.4
—
—
—
0
0
19
200
0.95
0.03
6.8
3.8
—
—
—
0
0
49
502
0.98
0.03
2.2
2.2
128.74
129.68
g/l
0.10
38
408
40
389
1.03
0.03
1.1
1.1
69.17
1558.86
iu/ml
—
6
86
16
152
1.05
0.02
1.1
1.0
0.11
2.72
u/ml
—
5
31
78
791
0.99
0.02
1.8
1.9
0.82
1.66
ug/l
0.96
68
698
68
670
1.02
0.02
1.4
1.4
294.63
291.68
ug/g
0.04
38
372
13
137
0.95
0.01
1.0
1.0
287.14
309.51
ng/l
—
7
94
26
267
0.97
0.01
1.2
1.1
—
—
—
0
0
13
136
0.96
0.00
1.0
1.0
736.57
718.75
ng/l
—
7
92
10
99
1.01
0.00
1.9
2.1
1.22
2.27
ug/l
—
10
83
17
166
1.02
0.00
1.1
1.1
391.06
395.77
nmol/l
0.03
17
150
26
264
0.98
0.00
1.3
1.4
—
—
—
0
0
22
218
1.01
0.00
1.4
2.3
—
—
—
0
0
238
2384
1.00
0.00
1.4
1.3
—
—
—
0
0
40
403
0.99
0.00
1.6
1.3
63.73
63.38
mmol/l
0.02
33
329
19
187
1.02
0.00
1.4
1.6
—
—
—
0
0
5
57
0.88
0.00
1.2
1.3
47.28
48.46
%
—
5
51
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
114.83
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
67
0.90
-0.00
2.8
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
40.14
—
0
5
0
7
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.42
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
168.33
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
66.87
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
1234.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.0
—
402.80
—
0
5
18
180
1.00
-0.00
1.4
1.4
—
—
—
0
0
9
90
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
8861.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
0.03
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
75
0.93
-0.00
1.7
1.6
—
—
—
0
0
5
51
0.98
-0.00
2.0
1.1
338.20
295.08
pmol/l
—
5
37

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_FACE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_FACE 0.859 [0.77, 0.96] 0.009
Birth year 0.997 [0.99, 1.01] 0.513

During the follow-up period (1.1.1998 — 31.12.2019), 755 out of 8978 females with CD2_BENIGN_MELANOCYTIC_FACE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_FACE 0.856 [0.76, 0.97] 0.013
Birth year 0.993 [0.98, 1.0] 0.108

During the follow-up period (1.1.1998 — 31.12.2019), 590 out of 4616 males with CD2_BENIGN_MELANOCYTIC_FACE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_FACE.

N-year risk Females Males
1 0.072% 0.191%
5 0.436% 1.109%
10 1.176% 2.921%
15 2.395% 5.773%
20 4.597% 9.912%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_FACE – Melanocytic naevi of other and unspecified parts of face

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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